DK125021B - Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds. - Google Patents

Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds.

Info

Publication number: DK125021B
Authority: DK; Denmark
Prior art keywords: tetrahydro; phenyl; preparation; acid addition; addition salts
Prior art date: 1970-01-06

Application number

DK2571AA

Other languages

Danish (da)

Inventor

A Rheiner

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-01-06

Filing date

1971-01-05

Publication date

1972-12-18

1971-01-05 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1972-12-18 Publication of DK125021B publication Critical patent/DK125021B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK2571AA 1970-01-06 1971-01-05 Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds. DK125021B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH10370A CH527194A (en)	1970-01-06	1970-01-06	Process for the preparation of isoquinoline derivatives

Publications (1)

Publication Number	Publication Date
DK125021B true DK125021B (en)	1972-12-18

Family

ID=4179328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK2571AA DK125021B (en)	1970-01-06	1971-01-05	Analogous process for the preparation of 1,2,3,4-tetrahydro-4-phenyl-isoquinoline derivatives or acid addition salts thereof or the corresponding optically active compounds.

Country Status (19)

Country	Link
JP (1)	JPS5515476B1 (en)
AT (1)	AT303041B (en)
BE (1)	BE761219A (en)
CA (1)	CA999866A (en)
CH (2)	CH527194A (en)
DE (1)	DE2062001C2 (en)
DK (1)	DK125021B (en)
ES (1)	ES387016A1 (en)
FI (1)	FI49503C (en)
FR (1)	FR2081412B1 (en)
GB (1)	GB1335261A (en)
IE (1)	IE34859B1 (en)
IL (1)	IL35916A (en)
NL (1)	NL171444C (en)
NO (1)	NO135315C (en)
PH (1)	PH9682A (en)
SE (3)	SE386672B (en)
YU (1)	YU33660B (en)
ZA (1)	ZA708590B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4595688A (en) *	1983-06-23	1986-06-17	Mcneilab, Inc.	Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) *	1983-06-23	1986-01-29	Mcneil Pharmaceutical	Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) *	1983-06-23	1988-01-12	Mcneilab, Inc.	Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) *	1992-10-14	1994-04-20	Merck & Co Inc	HIV integrase inhibitors
CA2389300C (en) *	1999-11-03	2010-06-08	Albany Molecular Research, Inc.	4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
PT1246806E (en)	1999-11-03	2008-04-03	Amr Technology Inc	Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) *	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1113007A1 (en) *	1999-12-24	2001-07-04	Pfizer Inc.	Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
EP1299393A2 (en) *	2000-07-11	2003-04-09	Bristol-Myers Squibb Pharma Company	4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
RU2388751C2 (en)	2004-07-15	2010-05-10	Амр Текнолоджи, Инк.	Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof for inhibiting norepinephrine, dopamine and serotonin reuptake
DE602006002894D1 (en)	2005-06-17	2008-11-06	Janssen Pharmaceutica Nv	naphthyridine
KR101594898B1 (en)	2005-07-15	2016-02-18	알바니 몰레큘라 리써치, 인크.	Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (en)	2008-06-04	2010-07-28	Bristol Myers Squibb Co	CRYSTAL FORM OF 6 - ((4S) -2-METHYL-4- (2-NAFTIL) -1,2,3,4-TETRAHYDROISOQUINOLIN-7-IL) PIRIDAZIN-3-AMINA
JP5739415B2 (en)	2009-05-12	2015-06-24	ブリストル−マイヤーズスクウィブカンパニー	(S) -7-([1,2,4] triazolo [1,5-a] pyridin-6-yl) -4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydroisoquinoline Crystal forms and uses thereof
CN102458123A (en)	2009-05-12	2012-05-16	阿尔巴尼分子研究公司	Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
CN102595902B (en)	2009-05-12	2015-04-29	阿尔巴尼分子研究公司	7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670694B2 (en) *	1966-05-05	1976-07-22	Hoechst Ag, 6000 Frankfurt	METHOD FOR MANUFACTURING TETRAHYDROISOCHINOLINES

1970
- 1970-01-06 CH CH10370A patent/CH527194A/en not_active IP Right Cessation
- 1970-01-06 CH CH1011872A patent/CH538477A/en not_active IP Right Cessation
- 1970-12-16 DE DE2062001A patent/DE2062001C2/en not_active Expired
- 1970-12-16 SE SE7313623A patent/SE386672B/en unknown
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/en unknown
- 1970-12-28 IL IL35916A patent/IL35916A/en unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/en not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/en active
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/en unknown
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-05 AT AT4571A patent/AT303041B/en not_active IP Right Cessation
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-05 BE BE761219A patent/BE761219A/en not_active IP Right Cessation
- 1971-01-05 DK DK2571AA patent/DK125021B/en not_active IP Right Cessation
- 1971-01-05 ES ES387016A patent/ES387016A1/en not_active Expired
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-06 YU YU19/71A patent/YU33660B/en unknown
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/en unknown

Also Published As

Publication number	Publication date
IL35916A (en)	1973-11-28
CH527194A (en)	1972-08-31
NL171444C (en)	1983-04-05
ZA708590B (en)	1971-09-29
JPS5515476B1 (en)	1980-04-23
CA999866A (en)	1976-11-16
DE2062001A1 (en)	1971-07-15
AT303041B (en)	1972-11-10
PH9682A (en)	1976-02-10
SE368401B (en)	1974-07-01
ES387016A1 (en)	1976-05-01
FI49503C (en)	1975-07-10
SE386672B (en)	1976-08-16
YU33660B (en)	1977-12-31
YU1971A (en)	1977-06-30
DE2062001C2 (en)	1986-10-16
NL7018956A (en)	1971-07-08
IL35916A0 (en)	1971-02-25
NO135315B (en)	1976-12-13
FI49503B (en)	1975-04-01
FR2081412A1 (en)	1971-12-03
NO135315C (en)	1977-03-23
IE34859B1 (en)	1975-09-03
IE34859L (en)	1971-07-06
BE761219A (en)	1971-07-05
FR2081412B1 (en)	1974-04-12
NL171444B (en)	1982-11-01
CH538477A (en)	1973-06-30
GB1335261A (en)	1973-10-24
SE399879B (en)	1978-03-06

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Legal Events

Date	Code	Title	Description
1988-09-19	PBP	Patent lapsed