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DK1034173T3 - Fremgangsmåde til fremstilling af 8-methoxy-quinoloncarboxylsyrer - Google Patents

Fremgangsmåde til fremstilling af 8-methoxy-quinoloncarboxylsyrer

Info

Publication number
DK1034173T3
DK1034173T3 DK98959874T DK98959874T DK1034173T3 DK 1034173 T3 DK1034173 T3 DK 1034173T3 DK 98959874 T DK98959874 T DK 98959874T DK 98959874 T DK98959874 T DK 98959874T DK 1034173 T3 DK1034173 T3 DK 1034173T3
Authority
DK
Denmark
Prior art keywords
methoxy
preparation
carboxylic acids
quinolone carboxylic
quinolone
Prior art date
Application number
DK98959874T
Other languages
Danish (da)
English (en)
Inventor
Reinhold Gehring
Klaus Mohrs
Werner Heilmann
Herbert Diehl
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1034173T3 publication Critical patent/DK1034173T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK98959874T 1997-11-24 1998-11-12 Fremgangsmåde til fremstilling af 8-methoxy-quinoloncarboxylsyrer DK1034173T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19751948A DE19751948A1 (de) 1997-11-24 1997-11-24 Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
EP98959874A EP1034173B1 (de) 1997-11-24 1998-11-12 Verfahren zur herstellung von 8-methoxy-chinoloncarbonsäuren
PCT/EP1998/007237 WO1999026940A2 (de) 1997-11-24 1998-11-12 Verfahren zur herstellung von 8-methoxy-chinoloncarbonsäuren

Publications (1)

Publication Number Publication Date
DK1034173T3 true DK1034173T3 (da) 2005-07-25

Family

ID=7849617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98959874T DK1034173T3 (da) 1997-11-24 1998-11-12 Fremgangsmåde til fremstilling af 8-methoxy-quinoloncarboxylsyrer

Country Status (41)

Country Link
US (2) US6897315B2 (ko)
EP (1) EP1034173B1 (ko)
JP (1) JP4445667B2 (ko)
KR (1) KR100589549B1 (ko)
CN (2) CN1151151C (ko)
AR (1) AR016694A1 (ko)
AT (1) ATE294169T1 (ko)
AU (1) AU732977B2 (ko)
BG (1) BG64532B1 (ko)
BR (1) BRPI9814894B8 (ko)
CA (2) CA2711645C (ko)
CO (1) CO5011069A1 (ko)
CU (1) CU22953A3 (ko)
CZ (1) CZ297212B6 (ko)
DE (2) DE19751948A1 (ko)
DK (1) DK1034173T3 (ko)
EE (1) EE04281B1 (ko)
ES (1) ES2241185T3 (ko)
HK (2) HK1034080A1 (ko)
HN (1) HN1998000179A (ko)
HR (1) HRP20000332B1 (ko)
HU (1) HU228337B1 (ko)
ID (1) ID26840A (ko)
IL (1) IL135866A0 (ko)
IN (1) IN189753B (ko)
MY (1) MY129324A (ko)
NO (1) NO315748B1 (ko)
NZ (1) NZ504657A (ko)
PE (1) PE20000007A1 (ko)
PL (1) PL192461B1 (ko)
PT (1) PT1034173E (ko)
RU (1) RU2219175C2 (ko)
SI (1) SI1034173T1 (ko)
SK (1) SK285492B6 (ko)
SV (1) SV1998000139A (ko)
TR (1) TR200001472T2 (ko)
TW (1) TW513427B (ko)
UA (1) UA56286C2 (ko)
UY (1) UY25265A1 (ko)
WO (1) WO1999026940A2 (ko)
ZA (1) ZA9810669B (ko)

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US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
WO2003099815A1 (en) 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
WO2004091619A1 (en) * 2003-04-09 2004-10-28 Dr. Reddy's Laboratories Limited A crystalline form iii of anhydrous moxifloxacin hydrochloride and a process for preparation thereof
EP1651630A1 (en) * 2003-08-05 2006-05-03 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
JP5255183B2 (ja) 2003-09-04 2013-08-07 ウォックハート リミテッド ベンゾキノリジン−2−カルボン酸アルギニン塩四水和物
ITMI20032259A1 (it) * 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
US7759362B2 (en) * 2004-04-21 2010-07-20 Institut Of Medicinal Biotechnology Chinese Academy Of Medical Sciences Quinolonecarboxylic acid compounds, preparation methods and pharmaceutical uses thereof
WO2006134491A2 (en) * 2005-06-14 2006-12-21 Aurobindo Pharma Limited New crystalline form of moxifloxacin hydrochloride and process for its preparation
ES2311391B1 (es) * 2007-02-07 2009-12-22 Quimica Sintetica, S.A. Forma cristalina de moxifloxacino base.
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
IT1393337B1 (it) 2009-03-06 2012-04-20 Italiana Sint Spa Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
IT1398952B1 (it) * 2010-03-19 2013-03-28 F S I Fabbrica Italiana Sint Processo di preparazione della moxifloxacina e suoi sali
CN102030751B (zh) * 2010-12-01 2012-11-21 上虞京新药业有限公司 一种盐酸莫西沙星的结晶工艺
CN104370906A (zh) * 2014-11-17 2015-02-25 安徽美诺华药物化学有限公司 氟喹诺酮衍生物的制备方法
CN104370907A (zh) * 2014-11-17 2015-02-25 安徽美诺华药物化学有限公司 喹诺酮衍生物的制备方法
CN104447742A (zh) * 2014-11-17 2015-03-25 安徽美诺华药物化学有限公司 一种喹诺酮衍生物的制备方法
CN104447741A (zh) * 2014-11-17 2015-03-25 安徽美诺华药物化学有限公司 一种氟喹诺酮衍生物的制备方法

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PT77267B (en) * 1982-09-07 1986-03-21 Lilly Co Eli Improved process for preparing novel octahydrobenz <f> isoquinolines or compounds relating thereto
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd 8位置換キノロンカルボン酸誘導体
FI871419A (fi) * 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
EP0342675B1 (en) * 1988-05-19 1995-01-25 Chugai Seiyaku Kabushiki Kaisha Novel quinolonecarboxylic acid derivatives
DE3906365A1 (de) 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
CA1336090C (en) 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
WO1990006305A1 (en) 1988-12-09 1990-06-14 Dainippon Pharmaceutical Co., Ltd. Quinolonecarboxylic acid derivatives, process for their preparation and medicinal composition containing same
JP2761566B2 (ja) 1989-03-10 1998-06-04 吉富製薬株式会社 ピリドンカルボン酸化合物
WO1992009579A1 (en) 1990-11-30 1992-06-11 Yoshitomi Pharmaceutical Industries, Ltd. Quinolonecarboxylic acid compound and its use
JPH05117238A (ja) 1991-10-23 1993-05-14 Chugai Pharmaceut Co Ltd キノロンカルボン酸誘導体の製造方法及びその合成中間体
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NO304832B1 (no) * 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
DE4230804A1 (de) 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4232172A1 (de) 1992-09-25 1994-03-31 Bayer Ag 7-(Aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)chinolon- und Naphthyridoncarbonsäure-Derivate
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
DE4234330A1 (de) * 1992-10-12 1994-04-14 Bayer Ag Chinoloncarbonsäuren
EP0677522A4 (en) * 1992-12-28 1995-12-27 Yoshitomi Pharmaceutical 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE.
CA2114981A1 (en) * 1993-02-09 1994-08-10 Kazumi Ogata Quinolonecarboxylic acid derivatives
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
US5631266A (en) * 1993-04-26 1997-05-20 Korea Research Institute Of Chemical Technology Quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
GB2289674A (en) 1994-05-23 1995-11-29 Pfizer Antibacterial naphthyridine
DE4435479A1 (de) 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
AU713704B2 (en) * 1996-01-31 1999-12-09 Sankyo Company Limited Agents for the treatment and prevention of aids

Also Published As

Publication number Publication date
EP1034173B1 (de) 2005-04-27
UA56286C2 (uk) 2003-05-15
HRP20000332A2 (en) 2001-04-30
AU732977B2 (en) 2001-05-03
SI1034173T1 (en) 2005-10-31
AR016694A1 (es) 2001-07-25
NO315748B1 (no) 2003-10-20
TW513427B (en) 2002-12-11
US20050209276A1 (en) 2005-09-22
US20030208069A1 (en) 2003-11-06
SK7482000A3 (en) 2000-10-09
NZ504657A (en) 2001-04-27
CN1200938C (zh) 2005-05-11
CA2311540C (en) 2011-06-14
CN1279683A (zh) 2001-01-10
CA2711645A1 (en) 1999-06-03
BRPI9814894B1 (pt) 2011-10-18
SK285492B6 (sk) 2007-02-01
AU1561999A (en) 1999-06-15
WO1999026940A3 (de) 1999-08-12
ID26840A (id) 2001-02-15
CU22953A3 (es) 2004-06-21
UY25265A1 (es) 1999-07-19
HUP0004337A3 (en) 2004-07-28
MY129324A (en) 2007-03-30
PL341088A1 (en) 2001-03-26
ZA9810669B (en) 1999-05-26
CZ297212B6 (cs) 2006-10-11
BG104467A (en) 2001-08-31
US6897315B2 (en) 2005-05-24
EP1034173A2 (de) 2000-09-13
IN189753B (ko) 2003-04-19
DE19751948A1 (de) 1999-05-27
CN1418879A (zh) 2003-05-21
CA2711645C (en) 2016-04-26
HRP20000332B1 (en) 2009-01-31
PL192461B1 (pl) 2006-10-31
ATE294169T1 (de) 2005-05-15
CA2311540A1 (en) 1999-06-03
CO5011069A1 (es) 2001-02-28
KR100589549B1 (ko) 2006-06-14
TR200001472T2 (tr) 2002-06-21
NO20002637L (no) 2000-05-23
HN1998000179A (es) 1999-02-09
SV1998000139A (es) 1999-04-13
CZ20001926A3 (cs) 2000-11-15
HK1034080A1 (en) 2001-10-12
PT1034173E (pt) 2005-08-31
HUP0004337A2 (hu) 2001-10-28
BRPI9814894B8 (pt) 2021-07-06
JP4445667B2 (ja) 2010-04-07
US7115744B2 (en) 2006-10-03
JP2001524477A (ja) 2001-12-04
NO20002637D0 (no) 2000-05-23
PE20000007A1 (es) 2000-03-05
BG64532B1 (bg) 2005-06-30
HK1056169A1 (en) 2004-02-06
HU228337B1 (en) 2013-03-28
ES2241185T3 (es) 2005-10-16
DE59812758D1 (de) 2005-06-02
CN1151151C (zh) 2004-05-26
WO1999026940A2 (de) 1999-06-03
RU2219175C2 (ru) 2003-12-20
EE04281B1 (et) 2004-04-15
EE200000241A (et) 2001-06-15
IL135866A0 (en) 2001-05-20
KR20010032361A (ko) 2001-04-16
BRPI9814894A (pt) 2000-10-03

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