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DK0831877T3 - Metabolske virkninger af visse glutathionanaloge - Google Patents

Metabolske virkninger af visse glutathionanaloge

Info

Publication number
DK0831877T3
DK0831877T3 DK96918156T DK96918156T DK0831877T3 DK 0831877 T3 DK0831877 T3 DK 0831877T3 DK 96918156 T DK96918156 T DK 96918156T DK 96918156 T DK96918156 T DK 96918156T DK 0831877 T3 DK0831877 T3 DK 0831877T3
Authority
DK
Denmark
Prior art keywords
metabolic effects
esters
certain
glutathione analogues
analogues
Prior art date
Application number
DK96918156T
Other languages
English (en)
Inventor
Richard F Borch
Matthew H Lyttle
Lawrence M Kauvar
Amy S Morgan
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/482,645 external-priority patent/US5767086A/en
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DK0831877T3 publication Critical patent/DK0831877T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK96918156T 1995-06-07 1996-06-05 Metabolske virkninger af visse glutathionanaloge DK0831877T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/482,645 US5767086A (en) 1992-04-03 1995-06-07 Bone marrow stimulation by certain glutathione analogs
US63651696A 1996-04-19 1996-04-19
PCT/US1996/009057 WO1996040205A1 (en) 1995-06-07 1996-06-05 Metabolic effects of certain glutathione analogs

Publications (1)

Publication Number Publication Date
DK0831877T3 true DK0831877T3 (da) 2005-02-14

Family

ID=27047352

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96918156T DK0831877T3 (da) 1995-06-07 1996-06-05 Metabolske virkninger af visse glutathionanaloge

Country Status (10)

Country Link
EP (1) EP0831877B1 (da)
JP (2) JPH11507056A (da)
AT (1) ATE280582T1 (da)
AU (1) AU715524B2 (da)
CA (1) CA2221568C (da)
DE (1) DE69633722T2 (da)
DK (1) DK0831877T3 (da)
ES (1) ES2231814T3 (da)
PT (1) PT831877E (da)
WO (1) WO1996040205A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2089179C1 (ru) * 1995-12-14 1997-09-10 Закрытое акционерное общество "ВАМ" Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования
US6251857B1 (en) 1995-12-14 2001-06-26 Novelos Therapeutics, Inc. Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof
DE69925824D1 (de) 1998-04-16 2005-07-21 Teijin Ltd Glutathionderivate und dazugehörige dosisformen
US20070142267A1 (en) 1998-11-23 2007-06-21 Novelos Therapeutics, Inc. Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
RU2144374C1 (ru) 1998-11-23 2000-01-20 Закрытое акционерное общество "ВАМ" Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток
CN1185008C (zh) * 1999-01-27 2005-01-19 泰立克公司 含有谷胱甘肽类似物的治疗用组合物
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
TW200538149A (en) 2004-05-20 2005-12-01 Telik Inc Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
TWI317739B (en) * 2005-01-06 2009-12-01 Telik Inc Tripeptide and tetrapeptide sulfones
US20120251496A1 (en) * 2011-03-31 2012-10-04 Telik, Inc. Ezatiostat for treating multiple myeloma
CA2841203C (en) * 2011-06-21 2019-01-22 Nitto Denko Corporation Apoptosis-inducing agent
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
US10093931B2 (en) 2014-06-17 2018-10-09 Nitto Denko Corporation Apoptosis inducer
US10264976B2 (en) 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
EP4365289A3 (en) 2018-11-16 2024-07-10 Nitto Denko Corporation Rna interference delivery formulation and methods for malignant tumors
EP3973991A4 (en) 2019-05-14 2023-07-05 Keio University ANTI-TUMORS AND COMPOUNDING AGENTS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE469132B (sv) * 1989-06-16 1993-05-17 Kabigen Ab Polypeptider och farmaceutisk komposition innehaallande denna
BR9106114A (pt) * 1990-03-02 1993-03-09 Autoimmune Inc Metodo para tratar ou prevenir uma doenca auto-imune (ad) e formulacao farmaceutica
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
JP3253127B2 (ja) * 1991-06-07 2002-02-04 帝國製薬株式会社 生理活性ポリペプチド含有製剤

Also Published As

Publication number Publication date
DE69633722T2 (de) 2005-11-03
AU715524B2 (en) 2000-02-03
EP0831877A1 (en) 1998-04-01
EP0831877B1 (en) 2004-10-27
JP2006348048A (ja) 2006-12-28
JPH11507056A (ja) 1999-06-22
PT831877E (pt) 2005-03-31
CA2221568A1 (en) 1996-12-19
ES2231814T3 (es) 2005-05-16
AU6048196A (en) 1996-12-30
DE69633722D1 (de) 2004-12-02
JP4520443B2 (ja) 2010-08-04
WO1996040205A1 (en) 1996-12-19
ATE280582T1 (de) 2004-11-15
CA2221568C (en) 2010-05-04

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