DK0742795T3 - Immunstimulerende monoklonale antistoffer - Google Patents

Immunstimulerende monoklonale antistoffer

Info

Publication number: DK0742795T3
Authority: DK; Denmark
Prior art keywords: immunostimulating; monoclonal antibodies; tumor; elicts; immuno
Prior art date: 1994-01-31

Application number

DK95910891T

Other languages

English (en)

Inventor

Britta Hardy

Avraham Novogrodsky

Original Assignee

Mor Research Applic Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1995-01-30

Publication date

1999-06-14

1995-01-30 Application filed by Mor Research Applic Ltd filed Critical Mor Research Applic Ltd

1999-06-14 Application granted granted Critical

1999-06-14 Publication of DK0742795T3 publication Critical patent/DK0742795T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Zoology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Detergent Compositions (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

DK95910891T 1994-01-31 1995-01-30 Immunstimulerende monoklonale antistoffer DK0742795T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL10850194A IL108501A (en)	1994-01-31	1994-01-31	Antibodies and pharmaceutical compositions containing them
PCT/US1995/001137 WO1995020605A1 (en)	1994-01-31	1995-01-30	Immuno-stimulatory monoclonal antibodies

Publications (1)

Publication Number	Publication Date
DK0742795T3 true DK0742795T3 (da)	1999-06-14

Family

ID=11065761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95910891T DK0742795T3 (da)	1994-01-31	1995-01-30	Immunstimulerende monoklonale antistoffer

Country Status (20)

Country	Link
US (1)	US5897862A (da)
EP (1)	EP0742795B1 (da)
JP (1)	JP3478398B2 (da)
CN (1)	CN1052733C (da)
AT (1)	ATE171461T1 (da)
AU (1)	AU693526B2 (da)
CA (1)	CA2182289C (da)
DE (1)	DE69504955T2 (da)
DK (1)	DK0742795T3 (da)
EE (1)	EE03285B1 (da)
ES (1)	ES2124533T3 (da)
FI (1)	FI963004A (da)
IL (1)	IL108501A (da)
LT (1)	LT4225B (da)
LV (1)	LV11624B (da)
MD (1)	MD1374G2 (da)
MX (1)	MX9603080A (da)
NO (1)	NO317020B1 (da)
RU (1)	RU2155190C2 (da)
WO (1)	WO1995020605A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL129299A0 (en) *	1999-03-31	2000-02-17	Mor Research Applic Ltd	Monoclonal antibodies antigens and diagnosis of malignant diseases
IL145926A0 (en)	2001-10-15	2002-07-25	Mor Research Applic Ltd	Peptide epitopes of mimotopes useful in immunomodulation
IL149820A0 (en)	2002-05-23	2002-11-10	Curetech Ltd	Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
EP1537878B1 (en)	2002-07-03	2010-09-22	Ono Pharmaceutical Co., Ltd.	Immunopotentiating compositions
DE10311248A1 (de) *	2003-03-14	2004-09-30	Müller-Hermelink, Hans Konrad, Prof. Dr.	Humaner monoklonaler Antikörper
WO2006021955A2 (en) *	2004-08-23	2006-03-02	Mor Research Applications Ltd.	Use of bat monoclonal antibody for immunotherapy
EP3530736A3 (en)	2005-05-09	2019-11-06	ONO Pharmaceutical Co., Ltd.	Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
SG163554A1 (en)	2005-07-01	2010-08-30	Medarex Inc	Human monoclonal antibodies to programmed death ligand 1 (pd-l1)
US8354509B2 (en)	2007-06-18	2013-01-15	Msd Oss B.V.	Antibodies to human programmed death receptor PD-1
DK2242773T3 (da)	2008-02-11	2017-09-25	Cure Tech Ltd	Monoklonale antistoffer til tumorbehandling
MD3972C2 (ro) *	2009-03-11	2010-07-31	Ион МЕРЕУЦЭ	Remediu şi metodă de tratament al stărilor precanceroase
WO2013014668A1 (en)	2011-07-24	2013-01-31	Curetech Ltd.	Variants of humanized immunomodulatory monoclonal antibodies
US10570204B2 (en)	2013-09-26	2020-02-25	The Medical College Of Wisconsin, Inc.	Methods for treating hematologic cancers
US9580504B1 (en)	2013-11-07	2017-02-28	Curetech Ltd.	Pidilizumab monoclonal antibody therapy following stem cell transplantation
JOP20200094A1 (ar)	2014-01-24	2017-06-16	Dana Farber Cancer Inst Inc	جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar)	2014-01-31	2017-06-16	Children’S Medical Center Corp	جزيئات جسم مضاد لـ tim-3 واستخداماتها
TWI693232B (zh)	2014-06-26	2020-05-11	美商宏觀基因股份有限公司	與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
EP3191127A1 (en)	2014-09-13	2017-07-19	Novartis AG	Combination therapies of egfr inhibitors
TWI773646B (zh)	2015-06-08	2022-08-11	美商宏觀基因股份有限公司	結合lag-3的分子和其使用方法
MD3328419T2 (ro)	2015-07-30	2022-01-31	Macrogenics Inc	Molecule de legare la PD-1 şi procedee de utilizare a acestora
BR112018003186A2 (pt)	2015-09-01	2018-09-25	Agenus Inc.	anticorpos anti-pd-1 e seus métodos de uso
MX2018003689A (es)	2015-09-29	2018-04-30	Celgene Corp	Proteinas de union a pd-1 y metodos para usarlas.
CA3004138A1 (en)	2015-11-03	2017-05-11	Janssen Biotech, Inc.	Antibodies specifically binding pd-1 and tim-3 and their uses
EP3389714A4 (en)	2015-12-14	2019-11-13	MacroGenics, Inc.	BISPECIFIC MOLECULES HAVING IMMUNOREACTIVITY TO PD-1 AND CTLA-4 AND METHODS OF USE
BR112018076260A2 (pt)	2016-06-20	2019-03-26	Kymab Limited	anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina
SG11201901950TA (en)	2016-09-19	2019-04-29	Celgene Corp	Methods of treating immune disorders using pd-1 binding proteins
EP3515943A4 (en)	2016-09-19	2020-05-06	Celgene Corporation	METHODS OF TREATING VITILIGO WITH PD-1 BINDING PROTEINS
EP3551225A1 (en)	2016-12-07	2019-10-16	Agenus Inc.	Antibodies and methods of use thereof
GB202107994D0 (en)	2021-06-04	2021-07-21	Kymab Ltd	Treatment of cancer
WO2024160721A1 (en)	2023-01-30	2024-08-08	Kymab Limited	Antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5182368A (en) *	1986-06-13	1993-01-26	Ledbetter Jeffrey A	Ligands and methods for augmenting B-cell proliferation

1994
- 1994-01-31 IL IL10850194A patent/IL108501A/en not_active IP Right Cessation
1995
- 1995-01-30 EP EP95910891A patent/EP0742795B1/en not_active Expired - Lifetime
- 1995-01-30 AU AU18686/95A patent/AU693526B2/en not_active Expired
- 1995-01-30 DE DE69504955T patent/DE69504955T2/de not_active Expired - Lifetime
- 1995-01-30 WO PCT/US1995/001137 patent/WO1995020605A1/en not_active Application Discontinuation
- 1995-01-30 JP JP52021095A patent/JP3478398B2/ja not_active Expired - Lifetime
- 1995-01-30 CA CA002182289A patent/CA2182289C/en not_active Expired - Lifetime
- 1995-01-30 AT AT95910891T patent/ATE171461T1/de active
- 1995-01-30 ES ES95910891T patent/ES2124533T3/es not_active Expired - Lifetime
- 1995-01-30 MD MD96-0296A patent/MD1374G2/ro unknown
- 1995-01-30 DK DK95910891T patent/DK0742795T3/da active
- 1995-01-30 RU RU96116984/13A patent/RU2155190C2/ru active
- 1995-01-30 CN CN95192406A patent/CN1052733C/zh not_active Expired - Lifetime
- 1995-01-30 US US08/380,857 patent/US5897862A/en not_active Expired - Lifetime
- 1995-01-30 EE EE9600107A patent/EE03285B1/xx unknown
1996
- 1996-07-29 NO NO19963168A patent/NO317020B1/no not_active IP Right Cessation
- 1996-07-29 MX MX9603080A patent/MX9603080A/es not_active IP Right Cessation
- 1996-07-29 FI FI963004A patent/FI963004A/fi unknown
- 1996-07-30 LT LT96-115A patent/LT4225B/lt not_active IP Right Cessation
- 1996-09-06 LV LVP-96-317A patent/LV11624B/en unknown

Also Published As

Publication number	Publication date
AU693526B2 (en)	1998-07-02
NO963168L (no)	1996-09-27
NO317020B1 (no)	2004-07-26
ES2124533T3 (es)	1999-02-01
JPH09508390A (ja)	1997-08-26
IL108501A0 (en)	1994-05-30
US5897862A (en)	1999-04-27
MX9603080A (es)	1998-01-31
NO963168D0 (no)	1996-07-29
RU2155190C2 (ru)	2000-08-27
EE03285B1 (et)	2000-08-15
MD1374G2 (ro)	2000-09-30
FI963004A0 (fi)	1996-07-29
CA2182289C (en)	2003-10-21
AU1868695A (en)	1995-08-15
LT96115A (en)	1997-05-26
JP3478398B2 (ja)	2003-12-15
LV11624A (en)	1996-12-20
DE69504955T2 (de)	1999-05-27
CN1145077A (zh)	1997-03-12
EP0742795A1 (en)	1996-11-20
FI963004A (fi)	1996-09-27
CA2182289A1 (en)	1995-08-03
LV11624B (en)	1997-06-20
ATE171461T1 (de)	1998-10-15
MD1374F2 (en)	1999-12-31
EP0742795B1 (en)	1998-09-23
DE69504955D1 (de)	1998-10-29
LT4225B (en)	1997-10-27
WO1995020605A1 (en)	1995-08-03
IL108501A (en)	1998-10-30
CN1052733C (zh)	2000-05-24

Publication	Publication Date	Title
DK0742795T3 (da)	1999-06-14	Immunstimulerende monoklonale antistoffer
DE69221147D1 (de)	1997-09-04	Nicht glycosylierter Anti-CD3-IgG-Antikörper
DE69319662D1 (de)	1998-08-20	Monoklonale Antikörper gegen GP130-Protein
EP0597829A4 (en)	1992-02-27	NEW MONOCLONAL ANTIBODY DRESSES AGAINST A NEW ANTIGEN ASSOCIATED WITH HUMAN TUMORS.
DK666389D0 (da)	1989-12-22	Monoklonalt antistof
KR970702882A (ko)	1997-06-10	암치료 및 암탐지를 위한 종양세포 생성 단백질의 모노클로날 항체(monoclonal antibody to oncofetal protein for treating and detecting cancer)
DE68914244D1 (de)	1994-05-05	Monoklonaler Antikörper.
ATE71411T1 (de)	1992-01-15	Monoklonale antikoerper mit spezifitaet fuer membran-assoziierte antigene.
FI973484A (fi)	1997-10-24	Menetelmä immuunivasteen stimuloimiseksi
DE3586216D1 (de)	1992-07-23	Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
NO177311C (no)	1995-08-23	Anti-fucosylceramid monoklonalt antistoff
DE3785795D1 (de)	1993-06-17	Monoklonale anti-menschliche magenkrebs-antikoerper.
DK49291A (da)	1991-05-17	Gramnegativ-bakterieendotoxinblokerende, monoklonale antistoffer
DE3580482D1 (de)	1990-12-13	Monoklonale antikoerper und immunisierung damit.
DK69590D0 (da)	1990-03-16	Humane anti-rh(d) monoklonale antistoffer
DK474189A (da)	1990-03-28	Monoklonalt antistof
NO890116L (no)	1989-07-13	Monoklonale antistoffer.
DK413389A (da)	1990-02-25	Monoklonale antistoffer
AU4668889A (en)	1990-06-12	Monoclonal antibodies specific for tumor antigens
DE68916088D1 (de)	1994-07-21	Anti-CPBII-monoklonaler Antikörper.
NO903788D0 (no)	1990-08-29	Monoklonalt antistoff mot protein c.
DK220688D0 (da)	1988-04-22	Monoklonalt antistof
ATE58173T1 (de)	1990-11-15	Monoklonale antikoerper und immunisierung damit.