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DK0679154T3 - Ny krystallinsk form af en d-vitamininanalog - Google Patents

Ny krystallinsk form af en d-vitamininanalog

Info

Publication number
DK0679154T3
DK0679154T3 DK94904583.5T DK94904583T DK0679154T3 DK 0679154 T3 DK0679154 T3 DK 0679154T3 DK 94904583 T DK94904583 T DK 94904583T DK 0679154 T3 DK0679154 T3 DK 0679154T3
Authority
DK
Denmark
Prior art keywords
crystalline form
vitamin
analog
new crystalline
calcipotriol
Prior art date
Application number
DK94904583.5T
Other languages
English (en)
Inventor
Erik Torngaard Hansen
Andersen Niels Smidt Rastrup
Lene Hoffmeyer Ringborg
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10728784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0679154(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of DK0679154T3 publication Critical patent/DK0679154T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/02Apparatus characterised by being constructed of material selected for its chemically-resistant properties
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/321Catalytic processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/327Formation of non-aromatic carbon-to-carbon double bonds only
    • C07C5/333Catalytic processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/327Formation of non-aromatic carbon-to-carbon double bonds only
    • C07C5/333Catalytic processes
    • C07C5/3335Catalytic processes with metals
    • C07C5/3337Catalytic processes with metals of the platinum group
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02Apparatus characterised by their chemically-resistant properties
    • B01J2219/0204Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02Apparatus characterised by their chemically-resistant properties
    • B01J2219/0204Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
    • B01J2219/0236Metal based
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02Apparatus characterised by their chemically-resistant properties
    • B01J2219/025Apparatus characterised by their chemically-resistant properties characterised by the construction materials of the reactor vessel proper
    • B01J2219/0277Metal based
    • B01J2219/0286Steel
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
    • C07C2523/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
    • C07C2523/42Platinum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94904583.5T 1993-01-15 1994-01-07 Ny krystallinsk form af en d-vitamininanalog DK0679154T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300763A GB9300763D0 (en) 1993-01-15 1993-01-15 Chemical compound

Publications (1)

Publication Number Publication Date
DK0679154T3 true DK0679154T3 (da) 1998-03-30

Family

ID=10728784

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94904583.5T DK0679154T3 (da) 1993-01-15 1994-01-07 Ny krystallinsk form af en d-vitamininanalog

Country Status (17)

Country Link
US (2) US5763426A (da)
EP (1) EP0679154B1 (da)
JP (1) JP3729847B2 (da)
KR (1) KR100309751B1 (da)
CN (1) CN1040746C (da)
AT (1) ATE159717T1 (da)
AU (1) AU663249B2 (da)
CA (1) CA2151730C (da)
DE (1) DE69406529T2 (da)
DK (1) DK0679154T3 (da)
ES (1) ES2111287T3 (da)
FI (1) FI108638B (da)
GB (1) GB9300763D0 (da)
GR (1) GR3025668T3 (da)
NZ (1) NZ259679A (da)
RU (1) RU2128646C1 (da)
WO (1) WO1994015912A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU710931B2 (en) * 1996-02-28 1999-09-30 Sumitomo Pharmaceuticals Company, Limited Crystalline vitamin D derivative
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
LT2915534T (lt) * 1999-04-23 2018-06-25 Leo Pharma A/S Farmacinė kompozicija, vartojimui ant odos, apimanti vitaminą d ir kortikosteroidą, psoriazės gydymui
US20090098065A1 (en) * 2000-01-11 2009-04-16 Avikam Harel Composition and methods for the treatment of skin disorders
WO2004046097A1 (en) * 2002-11-18 2004-06-03 Teva Pharmaceutical Industries Ltd. A crystallization method for purification of calcipotriene
US8362287B2 (en) * 2004-03-18 2013-01-29 Leo Pharma A/S Stereoselective synthesis of vitamin D analogues
FR2871696B1 (fr) * 2004-06-17 2006-11-10 Galderma Sa Composition topique pour le traitement du psoriasis
TWI318203B (en) * 2004-09-01 2009-12-11 Leo Pharma As Epimerization of allylic alcohols
EP1917072B1 (en) * 2005-06-01 2013-02-27 Stiefel Research Australia Pty Ltd Vitamin formulation
DE602007010734D1 (de) * 2006-02-10 2011-01-05 Amgen Inc Hydratformen von amg706
WO2007082533A1 (en) * 2006-03-17 2007-07-26 Leo Pharma A/S Isomerisation of pharmaceutical intermediates
WO2008027532A2 (en) * 2006-08-29 2008-03-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions including vitamin d and corticosteroid
US20100056644A1 (en) * 2006-11-29 2010-03-04 Nilendu Sen Pharmaceutical compositions containing anhydrous calcipotriene
ES2272198B1 (es) * 2006-12-28 2008-06-01 Laboratorios Viñas S.A. Procedimiento para la obtencion de hidrato de calcipotriol.
EP1970048A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D
US10265265B2 (en) * 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP2008651A1 (en) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
EP2300408B1 (en) * 2008-05-08 2016-04-13 United Therapeutics Corporation Process for the preparation of treprostinil monohydrate and its use for storage and shipping
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same
MX2012007229A (es) 2009-12-22 2012-07-30 Leo Pharma As Composicion cutanea que comprende analogo de vitamina d y mezcla de solvente y tensioactivos.
US9254296B2 (en) 2009-12-22 2016-02-09 Leo Pharma A/S Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture
US20130023501A1 (en) * 2009-12-22 2013-01-24 Leo Pharma A/S Pharmaceutical composition comprising solvent mixture and a vitamin d derivative or analogue
CA2785253A1 (en) * 2009-12-22 2011-06-30 Leo Pharma A/S Calcipotriol monohydrate nanocrystals
EP2515912A4 (en) * 2009-12-22 2013-12-25 Leo Pharma As PHARMACEUTICAL COMPOSITION WITH VITAMIN D ANALOGON AND COLOSTERS-TENSID MIXTURE
EP2579852B1 (en) 2010-06-11 2014-12-31 Leo Pharma A/S A pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid
SI2686017T1 (sl) 2011-03-14 2019-11-29 Drug Delivery Solutions Ltd Očesna sestava
WO2012127037A2 (en) 2011-03-24 2012-09-27 Leo Pharma A/S A composition comprising lipid nanoparticles and a corticosteroid or vitamin d derivative
JP5652723B2 (ja) * 2012-08-17 2015-01-14 フォーモサ・ラボラトリーズ・インコーポレーテッド マキサカルシトールの新しい結晶形態
CN103724162A (zh) * 2014-01-07 2014-04-16 成都医路康医学技术服务有限公司 一种银屑病治疗药物卡泊三醇溶剂化物的制备方法
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457282A1 (fr) * 1979-05-23 1980-12-19 Roussel Uclaf Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
JPS59104358A (ja) 1982-12-03 1984-06-16 Teijin Ltd 1α,24−ジヒドロキシコレカルシフエロ−ルの一水塩及びその製造法
KR940010767B1 (ko) * 1985-08-02 1994-11-11 레오 파마슈티칼스 프로덕츠 리미티드 에이/에스(레벤스 케미스케 파브리크 프로덕션 사크티에셀스카브) 신규 비타민 d 동족체
GB9004544D0 (en) * 1990-03-01 1990-04-25 Leo Pharm Prod Ltd Novel treatment ii

Also Published As

Publication number Publication date
EP0679154A1 (en) 1995-11-02
FI108638B (fi) 2002-02-28
USRE39706E1 (en) 2007-06-26
FI952797A0 (fi) 1995-06-07
GB9300763D0 (en) 1993-03-03
AU663249B2 (en) 1995-09-28
RU2128646C1 (ru) 1999-04-10
KR950704249A (ko) 1995-11-17
CA2151730A1 (en) 1994-07-21
DE69406529D1 (de) 1997-12-04
NZ259679A (en) 1996-11-26
EP0679154B1 (en) 1997-10-29
AU5857394A (en) 1994-08-15
RU95116650A (ru) 1997-06-10
WO1994015912A1 (en) 1994-07-21
CA2151730C (en) 2005-01-04
FI952797A (fi) 1995-06-07
GR3025668T3 (en) 1998-03-31
US5763426A (en) 1998-06-09
DE69406529T2 (de) 1998-05-28
JP3729847B2 (ja) 2005-12-21
CN1040746C (zh) 1998-11-18
KR100309751B1 (ko) 2002-11-08
ES2111287T3 (es) 1998-03-01
ATE159717T1 (de) 1997-11-15
CN1115979A (zh) 1996-01-31
JPH08505612A (ja) 1996-06-18

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