Nothing Special   »   [go: up one dir, main page]

DE69102659D1 - Synthese von LH-RH-Analogen unter Anwendung eines zeitlich begrenzten minimalen Schutzes. - Google Patents

Synthese von LH-RH-Analogen unter Anwendung eines zeitlich begrenzten minimalen Schutzes.

Info

Publication number
DE69102659D1
DE69102659D1 DE69102659T DE69102659T DE69102659D1 DE 69102659 D1 DE69102659 D1 DE 69102659D1 DE 69102659 T DE69102659 T DE 69102659T DE 69102659 T DE69102659 T DE 69102659T DE 69102659 D1 DE69102659 D1 DE 69102659D1
Authority
DE
Germany
Prior art keywords
synthesis
analogues
limited time
minimal protection
minimal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69102659T
Other languages
English (en)
Other versions
DE69102659T2 (de
Inventor
John J Nestor
Natalie L Mcclure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE69102659D1 publication Critical patent/DE69102659D1/de
Application granted granted Critical
Publication of DE69102659T2 publication Critical patent/DE69102659T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/065—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for hydroxy functions, not being part of carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bipolar Integrated Circuits (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Amplifiers (AREA)
  • Escalators And Moving Walkways (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Golf Clubs (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Variable-Direction Aerials And Aerial Arrays (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Fuses (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Semiconductor Integrated Circuits (AREA)
DE69102659T 1990-02-20 1991-02-19 Synthese von LH-RH-Analogen unter Anwendung eines zeitlich begrenzten minimalen Schutzes. Expired - Lifetime DE69102659T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48242890A 1990-02-20 1990-02-20

Publications (2)

Publication Number Publication Date
DE69102659D1 true DE69102659D1 (de) 1994-08-04
DE69102659T2 DE69102659T2 (de) 1995-02-23

Family

ID=23916033

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69102659T Expired - Lifetime DE69102659T2 (de) 1990-02-20 1991-02-19 Synthese von LH-RH-Analogen unter Anwendung eines zeitlich begrenzten minimalen Schutzes.

Country Status (18)

Country Link
EP (1) EP0443532B1 (de)
JP (1) JP2927978B2 (de)
KR (1) KR0152276B1 (de)
AT (1) ATE107931T1 (de)
AU (1) AU639751B2 (de)
CA (1) CA2036657C (de)
DE (1) DE69102659T2 (de)
DK (1) DK0443532T3 (de)
ES (1) ES2057624T3 (de)
FI (1) FI102538B1 (de)
HK (1) HK43097A (de)
HU (1) HU208158B (de)
IE (1) IE71945B1 (de)
NO (1) NO309428B1 (de)
NZ (1) NZ237159A (de)
PH (1) PH31062A (de)
PT (1) PT96807B (de)
ZA (1) ZA911233B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104231055A (zh) 2013-06-18 2014-12-24 深圳翰宇药业股份有限公司 加尼瑞克前体以及由其制备醋酸加尼瑞克的方法
KR101971418B1 (ko) * 2017-06-30 2019-04-24 애니젠 주식회사 고세렐린의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301066A (en) * 1980-05-08 1981-11-17 American Home Products Corp. Preparation of (D-Trp 6)-LH-RH via the heptapeptide H-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists

Also Published As

Publication number Publication date
ATE107931T1 (de) 1994-07-15
CA2036657A1 (en) 1991-08-21
AU639751B2 (en) 1993-08-05
NZ237159A (en) 1992-11-25
HK43097A (en) 1997-04-11
JPH04211096A (ja) 1992-08-03
HU910543D0 (en) 1991-09-30
KR0152276B1 (ko) 1998-10-01
DK0443532T3 (da) 1994-07-25
PT96807A (pt) 1991-10-31
PT96807B (pt) 1998-07-31
JP2927978B2 (ja) 1999-07-28
IE910556A1 (en) 1991-08-28
EP0443532A2 (de) 1991-08-28
ES2057624T3 (es) 1994-10-16
EP0443532A3 (en) 1992-02-26
HUT57234A (en) 1991-11-28
FI102538B (fi) 1998-12-31
AU7117691A (en) 1991-08-22
IE71945B1 (en) 1997-03-12
HU208158B (en) 1993-08-30
FI102538B1 (fi) 1998-12-31
ZA911233B (en) 1992-10-28
CA2036657C (en) 2003-02-11
NO309428B1 (no) 2001-01-29
PH31062A (en) 1998-02-05
NO910664L (no) 1991-08-21
FI910788A (fi) 1991-08-21
KR910021411A (ko) 1991-12-20
NO910664D0 (no) 1991-02-19
FI910788A0 (fi) 1991-02-19
DE69102659T2 (de) 1995-02-23
EP0443532B1 (de) 1994-06-29

Similar Documents

Publication Publication Date Title
DK172089D0 (da) 1,3-dioxolanderivater samt fremgangsmaade til fremstilling deraf
MA22476A1 (fr) Bis-naphtalimides contenant des linkers derives d'acides amines comme agents anti-cancer
ATE236981T1 (de) Von menschlichen t-zellen immunodominante epiropen des virus der c-hepatitis
MC2040A1 (fr) Derives d'acides amines
ES2094888T3 (es) Procedimiento de preparacion de un aposito con matriz.
NO178665C (no) Fosfopeptider og sammensetning for kosmetiske formål
DE68922405D1 (de) Deletionsanaloga von magaininpeptiden.
ATE171708T1 (de) Flüssigphasensynthese von peptiden und peptidderivaten
DK0553016T3 (da) Hidtil ukendte naphtalenamider og -sulfonamider, fremgangsmåder til deres fremstilling samt farmaceutiske midler indeholdende dem
DE69102659D1 (de) Synthese von LH-RH-Analogen unter Anwendung eines zeitlich begrenzten minimalen Schutzes.
KR830004223A (ko) 싸이클 헥사펩티드 소마토스테틴 유사체의 제조방법
PT90504A (pt) Processo para a preparacao de alcoois peptidicos com actividade anticoagulante
AT365926B (de) Verfahren zum stabilisieren von pharmakologisch aktiven prostacyclinverbindungen
DK0378432T3 (da) Peptider, deres anvendelse til inhibering af modningen af T-lymfocytter og aktiviteten af makrofager samt fremgangsmåder til deres fremstilling
DE68912809D1 (de) Verfahren zur Herstellung von Bis(2,2,6,6-tetramethyl-4-piperidyl)amin.
ES2104688T3 (es) Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido.
DK134587A (da) Phenylurinstoffer
FI922184A (fi) Flytande diskmedelskomposition.
ES2054175T3 (es) Composicion de tinte para fibras de queratina.
BE820707A (fr) Compositions detergentes a base de polyphosphates d'amines
ES2085833B1 (es) Derivados de carboximetilidencicloheptimidazol y metodo para prepararlos.
DE68908958D1 (de) Peptide.
DE69015646D1 (de) Mittel zur anregung des haarwuchses.
KR860009040A (ko) 디펩티드와 아민과의 부가 화합물의 제조방법
IT1253878B (it) Derivati mono-, bi- o tricarbociclici di acidi fosfinici o fosfonici

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN