DE69027217D1 - TREATMENT OF INSULIN RESISTANT DIABETES - Google Patents
TREATMENT OF INSULIN RESISTANT DIABETESInfo
- Publication number
- DE69027217D1 DE69027217D1 DE69027217T DE69027217T DE69027217D1 DE 69027217 D1 DE69027217 D1 DE 69027217D1 DE 69027217 T DE69027217 T DE 69027217T DE 69027217 T DE69027217 T DE 69027217T DE 69027217 D1 DE69027217 D1 DE 69027217D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- resistant diabetes
- insulin resistant
- insulin
- diabetes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010022491 Insulin resistant diabetes Diseases 0.000 title abstract 2
- 201000005948 Donohue syndrome Diseases 0.000 abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 2
- 102000013275 Somatomedins Human genes 0.000 abstract 2
- 206010053547 Congenital generalised lipodystrophy Diseases 0.000 abstract 1
- 201000006705 Congenital generalized lipodystrophy Diseases 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 208000035369 Leprechaunism Diseases 0.000 abstract 1
- 206010024604 Lipoatrophy Diseases 0.000 abstract 1
- 201000011032 Werner Syndrome Diseases 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 208000022215 lipoatrophic diabetes Diseases 0.000 abstract 1
- 201000009099 lipoatrophic diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Insulin-like growth factor (IGF) is used for treatment of type A insulin-resistant diabetes by reduction of glucose levels. The treatment is applicable to Mendenhall's Syndrome, Werner Syndrome, leprechaunism, lipoatrophic diabetes, and other lipoatrophies.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898920381A GB8920381D0 (en) | 1989-09-08 | 1989-09-08 | Treatment of insulin-resistant diabetes |
PCT/GB1990/001399 WO1991003253A1 (en) | 1989-09-08 | 1990-09-10 | Treatment of insulin-resistant diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69027217D1 true DE69027217D1 (en) | 1996-07-04 |
DE69027217T2 DE69027217T2 (en) | 1996-10-02 |
Family
ID=10662782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69027217T Expired - Lifetime DE69027217T2 (en) | 1989-09-08 | 1990-09-10 | TREATMENT OF INSULIN RESISTANT DIABETES |
Country Status (11)
Country | Link |
---|---|
US (1) | US5674845A (en) |
EP (1) | EP0490955B1 (en) |
JP (1) | JP2513360B2 (en) |
AT (1) | ATE138578T1 (en) |
AU (1) | AU642665B2 (en) |
CA (1) | CA2066227A1 (en) |
DE (1) | DE69027217T2 (en) |
DK (1) | DK0490955T3 (en) |
ES (1) | ES2087162T3 (en) |
GB (1) | GB8920381D0 (en) |
WO (1) | WO1991003253A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
SE9201573D0 (en) * | 1992-05-19 | 1992-05-19 | Kabi Pharmacia Ab | USE OF IGF-1 |
EP0602210A1 (en) * | 1992-06-08 | 1994-06-22 | Pharmacia AB (reg.number 556131-9608) | Use of growth factor igf-i and/or igf-ii |
JPH08500123A (en) * | 1993-01-25 | 1996-01-09 | ザ ベス イスラエル ホスピタル アソシエイション | Method for modifying barrier properties of IGF-I sensitive cells, diagnostic method and screening method |
SE9402370D0 (en) | 1994-07-04 | 1994-07-04 | Pharmacia Ab | Use of IGF-I |
US5741776A (en) * | 1995-05-22 | 1998-04-21 | Genentech, Inc. | Method of administration of IGF-I |
US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
US5783556A (en) * | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
WO1998027813A1 (en) * | 1996-12-24 | 1998-07-02 | Amur Pharmaceuticals, Inc. | Methods for treating insulin resistance and identifying patients at risk for the disease |
US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
US6627746B1 (en) | 1998-04-17 | 2003-09-30 | Exelixis, Inc. | Nucleic acids and proteins of C. elegans insulin-like genes and uses thereof |
CZ300931B6 (en) * | 1998-07-08 | 2009-09-16 | Kirin-Amgen Inc. | Preparation in powder form for mucosal administration |
JP3141107B2 (en) * | 1998-11-16 | 2001-03-05 | 工業技術院長 | Human-derived bradion protein, DNA encoding the same, and uses thereof |
US6902898B2 (en) * | 1998-11-16 | 2005-06-07 | National Institute Of Advanced Industrial Science And Technology | Human derived bradeion proteins, DNA coding for the proteins, and uses thereof |
WO2000040613A1 (en) | 1999-01-06 | 2000-07-13 | Genentech, Inc. | Insulin-like growth factor (igf) i mutant variants |
PT1165119E (en) | 1999-04-08 | 2004-02-27 | Genentech Inc | COMPOSITION BASED ON POLIPEPTIDES WITH OPPOSED LOADS |
US6040292A (en) * | 1999-06-04 | 2000-03-21 | Celtrix Pharmaceuticals, Inc. | Methods for treating diabetes |
DK1282437T3 (en) | 2000-05-16 | 2008-06-30 | Genentech Inc | Treatment of cartilage disorders |
NZ526672A (en) | 2001-02-09 | 2006-10-27 | Genentech Inc | Process for forming crystalline human insulin-like growth factor-1 |
CA2702192A1 (en) | 2001-03-14 | 2002-09-19 | Genentech, Inc. | Igf antagonist peptides |
US20040138116A1 (en) * | 2002-08-30 | 2004-07-15 | Vincent Geenen | Tolerogenic approach for type 1 diabetes |
EP3609522A4 (en) * | 2017-04-10 | 2021-05-05 | Yoram Palti | Methods and compounds for treating diabetes |
CA3198225A1 (en) * | 2020-10-13 | 2022-04-21 | Betavive Ltd. | Method and compounds for treating diabetes and associated metabolic diseases |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU624596B2 (en) * | 1987-12-16 | 1992-06-18 | Genesis Systems Corporation | Method and system for detection and treatment of premenstrual syndrome |
US4988675A (en) * | 1988-02-05 | 1991-01-29 | Ciba-Geigy Corporation | Method for preventing secondary effects |
GB8819826D0 (en) * | 1988-08-20 | 1988-09-21 | Kabivitrum Ab | Glycosylated igf-1 |
-
1989
- 1989-09-08 GB GB898920381A patent/GB8920381D0/en active Pending
-
1990
- 1990-09-10 DE DE69027217T patent/DE69027217T2/en not_active Expired - Lifetime
- 1990-09-10 EP EP90913512A patent/EP0490955B1/en not_active Expired - Lifetime
- 1990-09-10 WO PCT/GB1990/001399 patent/WO1991003253A1/en active IP Right Grant
- 1990-09-10 JP JP2512643A patent/JP2513360B2/en not_active Expired - Lifetime
- 1990-09-10 CA CA002066227A patent/CA2066227A1/en not_active Abandoned
- 1990-09-10 DK DK90913512.1T patent/DK0490955T3/en active
- 1990-09-10 ES ES90913512T patent/ES2087162T3/en not_active Expired - Lifetime
- 1990-09-10 AT AT90913512T patent/ATE138578T1/en not_active IP Right Cessation
- 1990-09-10 AU AU63580/90A patent/AU642665B2/en not_active Ceased
-
1995
- 1995-03-27 US US08/412,222 patent/US5674845A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0490955B1 (en) | 1996-05-29 |
DE69027217T2 (en) | 1996-10-02 |
GB8920381D0 (en) | 1989-10-25 |
EP0490955A1 (en) | 1992-06-24 |
JPH05504547A (en) | 1993-07-15 |
CA2066227A1 (en) | 1991-03-09 |
WO1991003253A1 (en) | 1991-03-21 |
DK0490955T3 (en) | 1996-06-24 |
AU6358090A (en) | 1991-04-08 |
ATE138578T1 (en) | 1996-06-15 |
AU642665B2 (en) | 1993-10-28 |
ES2087162T3 (en) | 1996-07-16 |
JP2513360B2 (en) | 1996-07-03 |
US5674845A (en) | 1997-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ASTELLAS PHARMA INC., TOKIO/TOKYO, JP |