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DE69016531D1 - 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. - Google Patents

2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel.

Info

Publication number
DE69016531D1
DE69016531D1 DE69016531T DE69016531T DE69016531D1 DE 69016531 D1 DE69016531 D1 DE 69016531D1 DE 69016531 T DE69016531 T DE 69016531T DE 69016531 T DE69016531 T DE 69016531T DE 69016531 D1 DE69016531 D1 DE 69016531D1
Authority
DE
Germany
Prior art keywords
loweralkyl
aryl
pyridinylamino
indoles
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69016531T
Other languages
English (en)
Other versions
DE69016531T2 (de
Inventor
Richard Charles Dr Effland
David Gordon Dr Wettlaufer
Joseph Thomas Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69016531D1 publication Critical patent/DE69016531D1/de
Publication of DE69016531T2 publication Critical patent/DE69016531T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE69016531T 1989-08-02 1990-07-31 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. Expired - Fee Related DE69016531T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38841589A 1989-08-02 1989-08-02

Publications (2)

Publication Number Publication Date
DE69016531D1 true DE69016531D1 (de) 1995-03-16
DE69016531T2 DE69016531T2 (de) 1995-07-06

Family

ID=23534038

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69016531T Expired - Fee Related DE69016531T2 (de) 1989-08-02 1990-07-31 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel.

Country Status (17)

Country Link
EP (1) EP0415103B1 (de)
JP (1) JPH0674266B2 (de)
KR (1) KR0164595B1 (de)
AT (1) ATE118002T1 (de)
AU (1) AU628201B2 (de)
CA (1) CA2022488C (de)
DE (1) DE69016531T2 (de)
DK (1) DK0415103T3 (de)
ES (1) ES2068294T3 (de)
FI (1) FI95466C (de)
GR (1) GR3015228T3 (de)
IE (1) IE66601B1 (de)
IL (1) IL95251A (de)
NO (1) NO176398C (de)
NZ (1) NZ234726A (de)
PT (1) PT94880B (de)
ZA (1) ZA906048B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868190A (en) * 1988-12-27 1989-09-19 Hoechst-Roussel Pharmaceuticals, Inc. N-pyridinyl-9H-carbazol-9-amines
US5214038A (en) * 1991-04-15 1993-05-25 Hoechst-Roussel Pharmaceuticals Inc. 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the preparation thereof
US5202319A (en) * 1991-09-23 1993-04-13 Hoechst-Roussel Pharmaceuticals Inc. Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5459274A (en) * 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
US6100276A (en) * 1996-04-12 2000-08-08 Aventis Pharmaceuticals Inc. Isatin derivatives as acetylcholinesterase inhibitors and analgesics
IL130642A0 (en) * 1996-12-27 2000-06-01 Hoechst Marion Roussel Ltd N-(pyridinylamino)isoindolines and related compounds
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions
KR20230062160A (ko) 2021-10-29 2023-05-09 대우조선해양 주식회사 극지용 선박의 공조 시스템 및 상기 극지용 선박의 외기 흡입구조
KR20230062159A (ko) 2021-10-29 2023-05-09 대우조선해양 주식회사 극지용 선박의 발전기 엔진의 외기 흡입구조 및 상기 외기 흡입구조를 포함하는 극지용 선박
KR20230062158A (ko) 2021-10-29 2023-05-09 대우조선해양 주식회사 극지용 선박의 발전기 엔진의 외기 흡입구조 및 상기 외기 흡입구조를 포함하는 극지용 선박

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US4868190A (en) * 1988-12-27 1989-09-19 Hoechst-Roussel Pharmaceuticals, Inc. N-pyridinyl-9H-carbazol-9-amines
US4983615A (en) * 1989-06-28 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders

Also Published As

Publication number Publication date
FI95466C (fi) 1996-02-12
FI95466B (fi) 1995-10-31
NO903390L (no) 1991-02-04
NZ234726A (en) 1992-01-29
AU6000390A (en) 1991-02-07
NO176398C (no) 1995-03-29
ATE118002T1 (de) 1995-02-15
ES2068294T3 (es) 1995-04-16
PT94880B (pt) 1997-12-31
KR910004598A (ko) 1991-03-29
AU628201B2 (en) 1992-09-10
EP0415103A1 (de) 1991-03-06
GR3015228T3 (en) 1995-05-31
DK0415103T3 (da) 1995-06-19
IL95251A (en) 1996-08-04
KR0164595B1 (ko) 1999-01-15
ZA906048B (en) 1991-05-29
FI903820A0 (fi) 1990-07-31
DE69016531T2 (de) 1995-07-06
JPH0674266B2 (ja) 1994-09-21
CA2022488C (en) 2000-11-07
CA2022488A1 (en) 1991-02-03
PT94880A (pt) 1991-04-18
JPH03118378A (ja) 1991-05-20
EP0415103B1 (de) 1995-02-01
IL95251A0 (en) 1991-06-10
NO903390D0 (no) 1990-08-01
NO176398B (no) 1994-12-19
IE66601B1 (en) 1996-01-24
IE902788A1 (en) 1991-02-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee