DE69004455D1 - Alpha-adrenergene Rezeptor-Antagonisten. - Google Patents

Alpha-adrenergene Rezeptor-Antagonisten.

Info

Publication number: DE69004455D1
Authority: DE; Germany
Prior art keywords: receptor antagonists; adrenergic receptor; alpha adrenergic; alpha; antagonists
Prior art date: 1989-02-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE90301741T

Other languages

English (en)

Other versions

DE69004455T2 (de

Inventor

Thomas Wen-Fu Ku

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

GlaxoSmithKline LLC

SmithKline Beecham Corp

Original Assignee

GlaxoSmithKline LLC

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1990-02-19

Publication date

1993-12-16

1990-02-19 Application filed by GlaxoSmithKline LLC, SmithKline Beecham Corp filed Critical GlaxoSmithKline LLC

1993-12-16 Application granted granted Critical

1993-12-16 Publication of DE69004455D1 publication Critical patent/DE69004455D1/de

1994-03-10 Publication of DE69004455T2 publication Critical patent/DE69004455T2/de

2010-02-20 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DE90301741T 1989-02-23 1990-02-19 Alpha-adrenergene Rezeptor-Antagonisten. Expired - Fee Related DE69004455T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/315,370 US4981849A (en)	1989-02-23	1989-02-23	Alpha-adrenergic receptor antagonists

Publications (2)

Publication Number	Publication Date
DE69004455D1 true DE69004455D1 (de)	1993-12-16
DE69004455T2 DE69004455T2 (de)	1994-03-10

Family

ID=23224088

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE90301741T Expired - Fee Related DE69004455T2 (de)	1989-02-23	1990-02-19	Alpha-adrenergene Rezeptor-Antagonisten.

Country Status (4)

Country	Link
US (1)	US4981849A (de)
EP (1)	EP0384676B1 (de)
JP (1)	JPH02240085A (de)
DE (1)	DE69004455T2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5458883A (en) *	1994-01-12	1995-10-17	Duke University	Method of treating disorders of the eye
US20090253654A1 (en)	2005-09-22	2009-10-08	Galantos Pharma Gmbh	Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
EP1777222A1 (de)	2005-09-22	2007-04-25	Galantos Pharma GmbH	Cholinesterase Inhibitoren mit erhöter Blut Hirn Schranke Permeabilität zur Behandlung von kognitiven Störungen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE795451A (fr) *	1972-02-23	1973-08-16	Pfizer	Agents hypoglycemiants aza indoliques tricycliques
US3904645A (en) *	1972-02-23	1975-09-09	Pfizer	Tricyclicazaindole derivatives
US3906000A (en) *	1972-02-23	1975-09-16	Pfizer	Tricyclicazaindole derivatives
JPS5630176A (en) *	1979-08-22	1981-03-26	Hitachi Ltd	Character generator
US4469634A (en) *	1982-07-29	1984-09-04	Smithkline Beckman Corporation	Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines
DE3471308D1 (en) *	1983-10-17	1988-06-23	Synthelabo	Imidazoline derivatives, their preparation and therapeutical use
DE3525564A1 (de) *	1985-07-15	1987-02-05	Schering Ag	Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4769368A (en) *	1986-02-10	1988-09-06	Smithkline Beckman Corporation	2,3,4,8,9,9A-Hexahydro-4-aryl-1H-indeno(1,7-CD)azepines

1989
- 1989-02-23 US US07/315,370 patent/US4981849A/en not_active Expired - Fee Related
1990
- 1990-02-19 EP EP90301741A patent/EP0384676B1/de not_active Expired - Lifetime
- 1990-02-19 DE DE90301741T patent/DE69004455T2/de not_active Expired - Fee Related
- 1990-02-20 JP JP2039544A patent/JPH02240085A/ja active Pending

Also Published As

Publication number	Publication date
JPH02240085A (ja)	1990-09-25
EP0384676B1 (de)	1993-11-10
US4981849A (en)	1991-01-01
EP0384676A1 (de)	1990-08-29
DE69004455T2 (de)	1994-03-10

Publication	Publication Date	Title
ATE82273T1 (de)	1992-11-15	Leucotrien-antagonisten.
DE58908506D1 (de)	1994-11-17	Netzwerkschnittstelle.
DE69207351D1 (de)	1996-02-15	Fibrinogen-Rezeptor-Antagoniste
NO905436D0 (no)	1990-12-17	Alkyleringsfremgangsmaate.
TR970073A2 (tr)	1997-02-21	Alfa adrenerjik resentör antagonistleri olarak pirimidindion pirimidintrion,triazindion, tetrahidrokinazolindion türevleri.
FI902054A0 (fi)	1990-04-24	Ergonomisk sits.
DE59005551D1 (de)	1994-06-01	Alkalistabile antischaummittel.
MX9101311A (es)	1992-05-04	Antagonistas receptores de fibrinogeno
DE68914151D1 (de)	1994-04-28	Netzwerk-Sender-Empfänger.
IT1244575B (it)	1994-07-28	Basamento antisismico.
KR960700722A (ko)	1996-02-24	피브리노겐 수용체 길항제(Fibrinogen receptor antagonists)
TR199501389A2 (tr)	1996-07-21	Adesyon reseptörü antagonistleri (karsitlari).
DE69011732D1 (de)	1994-09-29	Serotonin-Antagonist.
NO902133L (no)	1990-11-16	Toveis stereomikroskop.
FI920987A0 (fi)	1992-03-06	Interleukin-4-receptor.
DE59000678D1 (de)	1993-02-11	Verlegbare bruecke.
DE69004455D1 (de)	1993-12-16	Alpha-adrenergene Rezeptor-Antagonisten.
DE3875030D1 (de)	1992-11-05	Leukotrien-antagonisten.
DE69015745D1 (de)	1995-02-16	NMDA-Antagonisten.
DE69004827D1 (de)	1994-01-13	Alpha-adrenergene Rezeptor-Antagonisten.
ATE111466T1 (de)	1994-09-15	Selektive adenosinrezeptor-verbindungen.
DE68916800D1 (de)	1994-08-18	Verbinder.
MX9203754A (es)	1992-09-30	Antagonistas de leucotrieno.
FI930108A0 (fi)	1993-01-12	Imidazopyridin-paf-antagonister
DE69008674D1 (de)	1994-06-09	Irreversible bombesin-antagonisten.

Legal Events

Date	Code	Title	Description
1994-12-08	8364	No opposition during term of opposition
2001-03-22	8339	Ceased/non-payment of the annual fee