Nothing Special   »   [go: up one dir, main page]

DE69942564D1 - Methoden und zusammensetzungen für die produktion von viruspartikeln - Google Patents

Methoden und zusammensetzungen für die produktion von viruspartikeln

Info

Publication number
DE69942564D1
DE69942564D1 DE69942564T DE69942564T DE69942564D1 DE 69942564 D1 DE69942564 D1 DE 69942564D1 DE 69942564 T DE69942564 T DE 69942564T DE 69942564 T DE69942564 T DE 69942564T DE 69942564 D1 DE69942564 D1 DE 69942564D1
Authority
DE
Germany
Prior art keywords
methods
compositions
production
virus particles
retroviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69942564T
Other languages
English (en)
Inventor
Christophe Torrent
Patrice Yeh
Michel Perricaudet
David Klatzmann
Jean-Loup Salzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Genopoietic SARL
Original Assignee
Aventis Pharma SA
Genopoietic SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA, Genopoietic SARL filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE69942564D1 publication Critical patent/DE69942564D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69942564T 1998-05-18 1999-05-18 Methoden und zusammensetzungen für die produktion von viruspartikeln Expired - Lifetime DE69942564D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9806258A FR2778670B1 (fr) 1998-05-18 1998-05-18 Methodes et compositions pour la production de particules virales
PCT/FR1999/001184 WO1999060144A1 (fr) 1998-05-18 1999-05-18 Methodes et compositions pour la production de particules virales

Publications (1)

Publication Number Publication Date
DE69942564D1 true DE69942564D1 (de) 2010-08-19

Family

ID=9526464

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69942564T Expired - Lifetime DE69942564D1 (de) 1998-05-18 1999-05-18 Methoden und zusammensetzungen für die produktion von viruspartikeln

Country Status (10)

Country Link
US (1) US6489142B1 (de)
EP (1) EP1078094B1 (de)
JP (1) JP2002539758A (de)
AT (1) ATE473282T1 (de)
AU (1) AU762973B2 (de)
CA (1) CA2332639A1 (de)
DE (1) DE69942564D1 (de)
FR (1) FR2778670B1 (de)
NZ (1) NZ508791A (de)
WO (1) WO1999060144A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE424114T1 (de) * 1998-10-01 2009-03-15 Univ Southern California Retrovirales genübertragungssystem und entsprechendes verwendungverfahren
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
EP1201750A1 (de) 2000-10-26 2002-05-02 Genopoietic Synthetische Viren und ihre Verwendungen
DE102007020895B3 (de) * 2007-05-04 2008-08-07 Dräger Safety AG & Co. KGaA Vorrichtung zur Aufnahme von Flüssigkeitsproben
CN103717240A (zh) * 2011-06-10 2014-04-09 蓝鸟生物公司 用于肾上腺脑白质营养不良症和肾上腺脊髓神经病的基因治疗载体
EP2568289A3 (de) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
US9347065B2 (en) 2012-03-29 2016-05-24 International Aids Vaccine Initiative Methods to improve vector expression and genetic stability
CN104884627A (zh) 2012-10-25 2015-09-02 托卡根公司 具有小型启动子盒的逆转录病毒载体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9508664A (pt) * 1994-09-02 1998-01-06 Gsf Forschungszentrum Umwelt Vetores retrovirais visados poe expressão de não auto-inativação
WO1997032481A1 (en) * 1996-03-07 1997-09-12 The Regents Of The University Of California Helper-free, totally defective adenovirus for gene therapy
AU728610B2 (en) * 1996-11-19 2001-01-11 University Of Alabama At Birmingham Research Foundation Chimeric retrovirus/adenovirus system

Also Published As

Publication number Publication date
EP1078094B1 (de) 2010-07-07
AU3829399A (en) 1999-12-06
FR2778670A1 (fr) 1999-11-19
NZ508791A (en) 2003-09-26
US6489142B1 (en) 2002-12-03
ATE473282T1 (de) 2010-07-15
WO1999060144A1 (fr) 1999-11-25
CA2332639A1 (fr) 1999-11-25
AU762973B2 (en) 2003-07-10
JP2002539758A (ja) 2002-11-26
FR2778670B1 (fr) 2002-12-13
EP1078094A1 (de) 2001-02-28

Similar Documents

Publication Publication Date Title
DE60024302D1 (de) Zelllinien und konstrukte für die herstellung von e1-deletierten adenoviren in abwesenheit von replikationskompetentem adenovirus
WO1999011764A3 (en) Methods for generating high titer helper-free preparations of recombinant aav vectors
IL193758A0 (en) Genetically engineered duckweed
ATE291633T1 (de) Rekombinante adenovirale vektoren, die chimäre fiberproteine exprimieren, für die zellspezifische infektion und genomische integration
DE59913833D1 (de) Strukturprotein von aav, seine herstellung und verwendung
DE69932599D1 (de) Künstliche chromosomen, die die genetische information für die bildung von rekombinantem virus enthalten
ATE473282T1 (de) Methoden und zusammensetzungen für die produktion von viruspartikeln
WO1999021976A3 (en) Rapid generation of stable mammalian cell lines producing high levels of recombinant proteins
WO2001004282A3 (en) Replication-competent anti-cancer vectors
WO1997026322A3 (en) Methods and compositions for inhibiting hexokinase
ATE386130T1 (de) Adenovirale vektoren für die gentherapie
DE69716581D1 (de) Retroviraler vektor und dessen verwendung in gentherapie
DE69535024D1 (de) Verpackungszellinie zur transkomplementierung von defektiven retroviren-vektoren
ATE355385T1 (de) Herstellung von rekombinanten adenoviren und von adenovirus-genbanken
WO2001040257A3 (en) Modified il-12 subunits and nucleic acids encoding them
CO4790179A1 (es) Procedimiento para la fabricacion de proteinas humanas por activacion genica endogena
WO2000053759A8 (en) Expression of human alpha-fetoprotein in mammalian cells
EP0843006A3 (de) Rekombinante prostataspezifische Antigen-Vektoren und diese verwendende Assays
AU4216599A (en) Hematopoietic progenitor cell gene transduction