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DE69938579D1 - Extrazelluläre Matrixproteine mit modifizierten Aminosäuren - Google Patents

Extrazelluläre Matrixproteine mit modifizierten Aminosäuren

Info

Publication number
DE69938579D1
DE69938579D1 DE69938579T DE69938579T DE69938579D1 DE 69938579 D1 DE69938579 D1 DE 69938579D1 DE 69938579 T DE69938579 T DE 69938579T DE 69938579 T DE69938579 T DE 69938579T DE 69938579 D1 DE69938579 D1 DE 69938579D1
Authority
DE
Germany
Prior art keywords
amino acids
extracellular matrix
modified amino
matrix proteins
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69938579T
Other languages
English (en)
Other versions
DE69938579T2 (de
Inventor
Elliott A Gruskin
Douglas D Buechter
Guanghui Zhang
Kevin Connolly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Surgical Corp
Original Assignee
United States Surgical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Surgical Corp filed Critical United States Surgical Corp
Application granted granted Critical
Publication of DE69938579D1 publication Critical patent/DE69938579D1/de
Publication of DE69938579T2 publication Critical patent/DE69938579T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69938579T 1998-10-09 1999-10-07 Extrazelluläre Matrixproteine mit modifizierten Aminosäuren Expired - Lifetime DE69938579T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/169,768 US6492508B1 (en) 1996-06-03 1998-10-09 Nucleic acids encoding extracellular matrix proteins
US169768 1998-10-09

Publications (2)

Publication Number Publication Date
DE69938579D1 true DE69938579D1 (de) 2008-06-05
DE69938579T2 DE69938579T2 (de) 2009-06-04

Family

ID=22617093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69938579T Expired - Lifetime DE69938579T2 (de) 1998-10-09 1999-10-07 Extrazelluläre Matrixproteine mit modifizierten Aminosäuren

Country Status (5)

Country Link
US (3) US6492508B1 (de)
EP (2) EP0992586B1 (de)
CA (4) CA2639620A1 (de)
DE (1) DE69938579T2 (de)
ES (1) ES2303364T3 (de)

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US6927287B1 (en) * 1996-06-03 2005-08-09 United States Surgical Corporation Nucleic acid encoding extracellular matrix protein or fragment thereof
DK1149111T3 (da) 1999-01-06 2009-12-14 Univ Southern California Fremgangsmåde og sammensætning til inhibering af angiogenese
ES2327812T3 (es) 1999-07-13 2009-11-04 University Of Southern California Nuevos metodos y composiciones para inhibir la angiogenesis utilizando bases antagonistas de mmp-9 y/o integrinas beta-1.
FR2807436B1 (fr) * 2000-04-10 2002-05-24 Meristem Therapeutics Methode d'obtention de fibres d'un polypeptide collagenique recombinant non-hydroxyle, et fibres de polypeptide collagenique recombinant non-hydroxyle ainsi obtenues
WO2003035692A2 (en) * 2001-10-23 2003-05-01 The Victoria University Of Manchester Modified peptides and their uses
US7390885B2 (en) 2001-11-26 2008-06-24 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7365167B2 (en) 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
US7491691B2 (en) * 2002-05-03 2009-02-17 Sindrey Dennis R Connective tissue stimulating peptides
WO2006130190A2 (en) * 2005-02-07 2006-12-07 Dickman Martin B Proline suppresses apoptosis
US10183986B2 (en) 2005-12-15 2019-01-22 Industrial Technology Research Institute Trimeric collagen scaffold antibodies
BRPI0915574A2 (pt) * 2008-07-09 2016-07-26 Profibrix Bv sequência nucleotídica, construção nucleotídica, célula ou linhagem celular, método para produção de fibrinogênio em um sistema de cultura de célula eucariótica, preparação de fibrinogênio, uso da preparação de fibrinogênio, método para seleção de célula ou linhagem celular
WO2010071938A1 (en) * 2008-12-24 2010-07-01 Commonwealth Scientific And Industrial Research Organisation Novel collagen constructs
WO2011065940A1 (en) 2009-11-24 2011-06-03 Biogen Idec Ma Inc. Method of supplementing culture media to prevent undesirable amino acid substitutions
EP2876165A1 (de) 2013-11-22 2015-05-27 ACIB GmbH Verbessertes Verfahren zur Herstellung modifizierter Target-Polypeptide

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Also Published As

Publication number Publication date
US6958223B2 (en) 2005-10-25
CA2284397A1 (en) 2000-04-09
EP0992586B1 (de) 2008-04-23
CA2284397C (en) 2008-12-16
ES2303364T3 (es) 2008-08-01
US6492508B1 (en) 2002-12-10
CA2639637A1 (en) 2000-04-09
US20040086961A1 (en) 2004-05-06
US20050196830A1 (en) 2005-09-08
EP1914311A1 (de) 2008-04-23
EP0992586A2 (de) 2000-04-12
DE69938579T2 (de) 2009-06-04
CA2639620A1 (en) 2000-04-09
CA2639757A1 (en) 2000-04-09
EP0992586A3 (de) 2004-04-21

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Legal Events

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8364 No opposition during term of opposition