DE69804273D1 - 5h-Thiazolo[3,2-a]pyrimidinderivate - Google Patents

5h-Thiazolo[3,2-a]pyrimidinderivate

Info

Publication number: DE69804273D1
Authority: DE; Germany
Prior art keywords: thiazolo; pyrimidine derivatives; pyrimidine; derivatives
Prior art date: 1997-07-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69804273T

Other languages

English (en)

Other versions

DE69804273T2 (de

Inventor

Geo Adam

Sabine Kolczewski

Vincent Mutel

Juergen Wichmann

Thomas Johannes Woltering

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-18

Filing date

1998-07-11

Publication date

2002-04-25

1998-07-11 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2002-04-25 Application granted granted Critical

2002-04-25 Publication of DE69804273D1 publication Critical patent/DE69804273D1/de

2002-10-31 Publication of DE69804273T2 publication Critical patent/DE69804273T2/de

2018-07-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
- C07D239/40—One sulfur atom as doubly bound sulfur atom or as unsubstituted mercapto radical

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Addiction (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE69804273T 1997-07-18 1998-07-11 5h-Thiazolo[3,2-a]pyrimidinderivate Expired - Fee Related DE69804273T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP97112324		1997-07-18

Publications (2)

Publication Number	Publication Date
DE69804273D1 true DE69804273D1 (de)	2002-04-25
DE69804273T2 DE69804273T2 (de)	2002-10-31

Family

ID=8227080

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69804273T Expired - Fee Related DE69804273T2 (de)	1997-07-18	1998-07-11	5h-Thiazolo[3,2-a]pyrimidinderivate

Country Status (33)

Country	Link
US (1)	US5958931A (de)
EP (1)	EP0891978B1 (de)
JP (1)	JP3100573B2 (de)
KR (1)	KR100296837B1 (de)
CN (1)	CN1102596C (de)
AR (1)	AR016129A1 (de)
AT (1)	ATE214704T1 (de)
AU (1)	AU738207B2 (de)
BR (1)	BR9802482A (de)
CA (1)	CA2243234C (de)
CO (1)	CO5210884A1 (de)
CZ (1)	CZ288944B6 (de)
DE (1)	DE69804273T2 (de)
DK (1)	DK0891978T3 (de)
ES (1)	ES2172840T3 (de)
HK (1)	HK1018439A1 (de)
HR (1)	HRP980398B1 (de)
HU (1)	HUP9801587A3 (de)
ID (1)	ID21824A (de)
IL (1)	IL125358A (de)
MA (1)	MA26520A1 (de)
NO (1)	NO310512B1 (de)
NZ (1)	NZ330988A (de)
PE (1)	PE97499A1 (de)
PL (1)	PL190218B1 (de)
PT (1)	PT891978E (de)
RU (1)	RU2197493C2 (de)
SI (1)	SI0891978T1 (de)
TR (1)	TR199801367A2 (de)
TW (1)	TW523518B (de)
UY (1)	UY25095A1 (de)
YU (1)	YU29798A (de)
ZA (1)	ZA986250B (de)

Families Citing this family (32)

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EP1074549B1 (de) *	1999-08-06	2003-11-19	F. Hoffmann-La Roche Ag	Tetrahydro-benzo(d)azepine und deren Verwendung als metabotrope Glutamatrezeptor-Antagonisten
CA2672805A1 (en) *	2001-01-31	2002-08-08	H. Lundbeck A/S	Pyrimidine derivatives
CA2451057A1 (en) *	2001-06-14	2002-12-27	Banyu Pharmaceutical Co., Ltd.	Novel isoxazolopyridone derivatives and use thereof
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine
RU2378277C2 (ru) *	2004-06-21	2010-01-10	Ф. Хоффманн-Ля Рош Аг	Производные пиразолпиримидина
KR100847160B1 (ko) *	2004-06-21	2008-07-17	에프. 호프만-라 로슈 아게	피라졸로 피리미딘 유도체
ES2365406T3 (es)	2005-02-11	2011-10-04	F. Hoffmann-La Roche Ag	Derivados de pirazolo-pirimidina como antagonistas de mglur2.
DK1863818T3 (da)	2005-03-23	2010-05-10	Hoffmann La Roche	Acetylenyl-pyrazolo-pyrimidinderivater som mglur2-antagonister
BRPI0616571A2 (pt)	2005-09-27	2011-06-21	Hoffmann La Roche	oxadiazolil pirazol-piridiminas como antagonistas de mglur2, processo para sua preparação, composição farmacêutica que os contém e uso dos mesmo
AR059898A1 (es)	2006-03-15	2008-05-07	Janssen Pharmaceutica Nv	Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en)	2007-03-07	2009-01-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
TW200845978A (en) *	2007-03-07	2008-12-01	Janssen Pharmaceutica Nv	3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
PL2203439T3 (pl)	2007-09-14	2011-06-30	Addex Pharmaceuticals Sa	1',3'-dipodstawione-4-fenylo-3,4,5,6-tetrahydro-2H, 1'H-[1, 4']bipirydynylo-2'-ketony
CN101848893B (zh)	2007-09-14	2012-06-06	奥梅-杨森制药有限公司	1,3-二取代的4-(芳基-x-苯基)-1h-吡啶-2-酮
NZ584148A (en) *	2007-09-14	2011-05-27	Ortho Mcneil Janssen Pharm	1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones
CN101861316B (zh) *	2007-11-14	2013-08-21	奥梅-杨森制药有限公司	咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
ES2439291T3 (es)	2008-09-02	2014-01-22	Janssen Pharmaceuticals, Inc.	Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos
EP2346505B1 (de)	2008-10-16	2014-04-23	Janssen Pharmaceuticals, Inc.	Indol- und benzomorpholinderivate als modulatoren von metabotropen glutamatrezeptoren
WO2010060589A1 (en)	2008-11-28	2010-06-03	Ortho-Mcneil-Janssen Pharmaceuticals, Inc.	Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
CN101503414B (zh) *	2009-03-04	2013-10-30	沈阳药科大学	噻唑并[3,2-b]-1,2,4-三嗪衍生物及其应用
MY153913A (en)	2009-05-12	2015-04-15	Janssen Pharmaceuticals Inc	7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
NZ596053A (en)	2009-05-12	2013-05-31	Janssen Pharmaceuticals Inc	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
PT2430022E (pt)	2009-05-12	2013-12-26	Janssen Pharmaceuticals Inc	Derivados de 1,2,3-triazolo[4,3-a]piridina e a sua utilização para o tratamento ou prevenção de doenças neurológicas e psiquiátricas
CA2814998C (en)	2010-11-08	2019-10-29	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
EP2649069B1 (de)	2010-11-08	2015-08-26	Janssen Pharmaceuticals, Inc.	1,2,4-triazol[4,3-a]pyridinderivate und ihre verwendung als positive allosterische mglur2-rezeptormodulatoren
US8993591B2 (en)	2010-11-08	2015-03-31	Janssen Pharmaceuticals, Inc.	1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors
JO3368B1 (ar)	2013-06-04	2019-03-13	Janssen Pharmaceutica Nv	مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
EP3055315B1 (de) *	2013-10-11	2018-07-25	F. Hoffmann-La Roche AG	Thiazolopyrimidinone als modulatoren der nmda rezeptoraktivität
RS61334B1 (sr)	2014-01-21	2021-02-26	Janssen Pharmaceutica Nv	Kombinacije koje obuhvataju pozitivne alosterične modulatore metabotropnog glutamatergičnog receptora podtipa 2 i njihova upotreba
HUE053734T2 (hu)	2014-01-21	2021-07-28	Janssen Pharmaceutica Nv	2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait tartalmazó kombinációk és alkalmazásuk
US11578083B2 (en) *	2017-03-31	2023-02-14	Basf Se	Pyrimidinium compounds and their mixtures for combating animal pests

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US3660418A (en) *	1970-03-16	1972-05-02	Sandoz Ag	Certain 2 3 5 6-tetrahydroimidazo(2 1-b)thiazoles
EP0524055A1 (de) *	1991-07-19	1993-01-20	Synthelabo	Imidazo(2,1-b)benzothiazolderivate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung
PL182285B1 (pl) *	1994-08-12	2001-12-31	Lilly Co Eli	Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL
GB9609976D0 (en) *	1996-05-13	1996-07-17	Lilly Industries Ltd	Pharmaceutical compounds
AU3783497A (en) *	1996-08-09	1998-03-06	Yamanouchi Pharmaceutical Co., Ltd.	Metabotropic glutamate receptor agonists

1998
- 1998-07-11 PT PT98112915T patent/PT891978E/pt unknown
- 1998-07-11 DE DE69804273T patent/DE69804273T2/de not_active Expired - Fee Related
- 1998-07-11 ES ES98112915T patent/ES2172840T3/es not_active Expired - Lifetime
- 1998-07-11 AT AT98112915T patent/ATE214704T1/de not_active IP Right Cessation
- 1998-07-11 EP EP98112915A patent/EP0891978B1/de not_active Expired - Lifetime
- 1998-07-11 SI SI9830130T patent/SI0891978T1/xx unknown
- 1998-07-11 DK DK98112915T patent/DK0891978T3/da active
- 1998-07-14 TR TR1998/01367A patent/TR199801367A2/xx unknown
- 1998-07-14 NO NO19983244A patent/NO310512B1/no not_active IP Right Cessation
- 1998-07-14 ID IDP981000A patent/ID21824A/id unknown
- 1998-07-14 NZ NZ330988A patent/NZ330988A/xx unknown
- 1998-07-14 MA MA25167A patent/MA26520A1/fr unknown
- 1998-07-14 ZA ZA986250A patent/ZA986250B/xx unknown
- 1998-07-14 US US09/115,191 patent/US5958931A/en not_active Expired - Fee Related
- 1998-07-15 PE PE1998000625A patent/PE97499A1/es not_active Application Discontinuation
- 1998-07-15 JP JP10199363A patent/JP3100573B2/ja not_active Expired - Fee Related
- 1998-07-15 YU YU29798A patent/YU29798A/sh unknown
- 1998-07-15 CA CA002243234A patent/CA2243234C/en not_active Expired - Fee Related
- 1998-07-15 CN CN98116063A patent/CN1102596C/zh not_active Expired - Fee Related
- 1998-07-15 IL IL12535898A patent/IL125358A/en not_active IP Right Cessation
- 1998-07-15 HU HU9801587A patent/HUP9801587A3/hu unknown
- 1998-07-16 HR HR980398A patent/HRP980398B1/xx not_active IP Right Cessation
- 1998-07-16 AR ARP980103469A patent/AR016129A1/es not_active Application Discontinuation
- 1998-07-16 CZ CZ19982239A patent/CZ288944B6/cs not_active IP Right Cessation
- 1998-07-16 CO CO98040510A patent/CO5210884A1/es not_active Application Discontinuation
- 1998-07-16 PL PL98327532A patent/PL190218B1/pl unknown
- 1998-07-16 KR KR1019980028788A patent/KR100296837B1/ko not_active IP Right Cessation
- 1998-07-16 UY UY25095A patent/UY25095A1/es unknown
- 1998-07-16 BR BR9802482-5A patent/BR9802482A/pt not_active Application Discontinuation
- 1998-07-17 AU AU77302/98A patent/AU738207B2/en not_active Ceased
- 1998-07-17 RU RU98114683/04A patent/RU2197493C2/ru not_active IP Right Cessation
- 1998-07-21 TW TW087111834A patent/TW523518B/zh not_active IP Right Cessation
1999
- 1999-07-14 HK HK99103032A patent/HK1018439A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CO5210884A1 (es)	2002-10-30
ID21824A (id)	1999-07-29
PL327532A1 (en)	1999-02-01
PL190218B1 (pl)	2005-11-30
CN1102596C (zh)	2003-03-05
EP0891978A3 (de)	1999-02-03
CZ223998A3 (cs)	1999-02-17
NO983244D0 (no)	1998-07-14
EP0891978B1 (de)	2002-03-20
MA26520A1 (fr)	2004-12-20
TW523518B (en)	2003-03-11
EP0891978A2 (de)	1999-01-20
AR016129A1 (es)	2001-06-20
CA2243234A1 (en)	1999-01-18
IL125358A0 (en)	1999-03-12
NO310512B1 (no)	2001-07-16
HRP980398B1 (en)	2002-06-30
TR199801367A3 (tr)	1999-02-22
CN1206010A (zh)	1999-01-27
YU29798A (sh)	2001-12-26
DE69804273T2 (de)	2002-10-31
DK0891978T3 (da)	2002-07-01
RU2197493C2 (ru)	2003-01-27
HUP9801587A2 (hu)	1999-11-29
UY25095A1 (es)	2001-01-31
TR199801367A2 (xx)	1999-02-22
JP3100573B2 (ja)	2000-10-16
KR100296837B1 (ko)	2001-10-26
US5958931A (en)	1999-09-28
IL125358A (en)	2002-09-12
ES2172840T3 (es)	2002-10-01
NZ330988A (en)	1999-03-29
KR19990013919A (ko)	1999-02-25
ZA986250B (en)	1999-01-22
ATE214704T1 (de)	2002-04-15
NO983244L (no)	1999-01-19
HK1018439A1 (en)	1999-12-24
HRP980398A2 (en)	1999-04-30
PT891978E (pt)	2002-07-31
CZ288944B6 (cs)	2001-10-17
AU7730298A (en)	1999-01-28
JPH1171380A (ja)	1999-03-16
PE97499A1 (es)	1999-10-12
BR9802482A (pt)	2000-03-14
CA2243234C (en)	2007-09-18
HUP9801587A3 (en)	2001-09-28
SI0891978T1 (en)	2002-06-30
AU738207B2 (en)	2001-09-13
HU9801587D0 (en)	1998-09-28

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DE69804273D1 (de)	2002-04-25	5h-Thiazolo[3,2-a]pyrimidinderivate
DK1220856T3 (da)	2005-03-14	Pyrazolo[4,3-d]pyrimidinderivater
IS5721A (is)	2000-11-21	Pýróló [2,3-dl]pírimídín efnasambönd
DE69915675D1 (de)	2004-04-22	Triazolo[4,5-d]pyrimidin-derivate
ID26698A (id)	2001-02-01	SENYAWA-SENYAWA PIROLO [2,3-d] PIRIMIDINA
MA26851A1 (fr)	2004-12-20	Derives de pyrrolo [2,3-d] pyrimidine
ATE256123T1 (de)	2003-12-15	Pyrimidonderivate
PT1005446E (pt)	2004-06-30	Derivados de n-aroilfenilalanina
PT915088E (pt)	2003-01-31	Derivados de d-prolina
PT1003719E (pt)	2002-10-31	Derivados microbicidas de n-sulfonil-glicinalquiniloxifenemetilamida
BR9507666A (pt)	1997-09-23	Novos derivados de pirimidina
PT1027362E (pt)	2005-08-31	Derivados de cetolidos 2-halogeno-6-o-substituidos
DE50001191D1 (de)	2003-03-06	Pyrazolo[4, 3-d]pyrimidine
DE69716901D1 (de)	2002-12-12	2,4-diaminopyrimidin-derivate
PT966437E (pt)	2002-11-29	Derivados de 5-aroilnaftaleno
NO995033D0 (no)	1999-10-15	6,7-disubstituerte-4-aminopyrido[2,3-D]pyrimidinforbindelser
NO995035D0 (no)	1999-10-15	5,6,7-trisubstituerte-4-aminopyrido[2,3-D]pyrimidinforbindelser
PT1010699E (pt)	2005-08-31	Derivados de 3-oxadiazolil-1,6-naftiridina-2(h)-ona substituido em 5
EP0954316A4 (de)	2002-02-13	Pyrimidine derivaten

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