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DE69611251D1 - Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges - Google Patents

Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges

Info

Publication number
DE69611251D1
DE69611251D1 DE69611251T DE69611251T DE69611251D1 DE 69611251 D1 DE69611251 D1 DE 69611251D1 DE 69611251 T DE69611251 T DE 69611251T DE 69611251 T DE69611251 T DE 69611251T DE 69611251 D1 DE69611251 D1 DE 69611251D1
Authority
DE
Germany
Prior art keywords
compositions containing
treating
hydroperoxeicosatetraic
dry eye
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69611251T
Other languages
English (en)
Other versions
DE69611251T2 (de
Inventor
M Yanni
A Gamache
T Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of DE69611251D1 publication Critical patent/DE69611251D1/de
Application granted granted Critical
Publication of DE69611251T2 publication Critical patent/DE69611251T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69611251T 1995-10-31 1996-08-19 Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges Expired - Fee Related DE69611251T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/551,021 US5696166A (en) 1995-10-31 1995-10-31 Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
PCT/US1996/013441 WO1997016179A1 (en) 1995-10-31 1996-08-19 Compositions containing hydroperoxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders

Publications (2)

Publication Number Publication Date
DE69611251D1 true DE69611251D1 (de) 2001-01-18
DE69611251T2 DE69611251T2 (de) 2001-04-05

Family

ID=24199512

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69611251T Expired - Fee Related DE69611251T2 (de) 1995-10-31 1996-08-19 Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges

Country Status (13)

Country Link
US (1) US5696166A (de)
EP (1) EP0858330B1 (de)
JP (1) JPH11515024A (de)
AT (1) ATE198044T1 (de)
AU (1) AU706373B2 (de)
CA (1) CA2234367C (de)
DE (1) DE69611251T2 (de)
DK (1) DK0858330T3 (de)
ES (1) ES2152556T3 (de)
GR (1) GR3035438T3 (de)
HK (1) HK1013194A1 (de)
PT (1) PT858330E (de)
WO (1) WO1997016179A1 (de)

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DK1330246T3 (da) * 2000-10-23 2005-08-08 Alcon Inc Anvendelse af hydroxyicosatetraensyrederivater ved intraokulær kirurgi
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CN1239161C (zh) * 2001-05-21 2006-02-01 爱尔康公司 可用于治疗干眼疾病的类固醇
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US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US6750250B1 (en) * 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
WO2003030892A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US20030109508A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
WO2003030893A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye by a combination of an antiinflammatory steroid and a muc-1 secretagogue
US20040002514A1 (en) * 2002-06-14 2004-01-01 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
US6825232B2 (en) * 2002-06-14 2004-11-30 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
FR2843026B1 (fr) * 2002-08-02 2006-01-06 Goemar Lab Sa Nouveau medicament
US7026296B2 (en) * 2002-09-20 2006-04-11 Alcon, Inc. Methods of treating dry eye disorders
WO2004060274A2 (en) * 2002-12-20 2004-07-22 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
WO2004093878A1 (en) 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
US8455016B2 (en) 2004-03-12 2013-06-04 Melbj Holdings, Llc Treatment for meibomian gland dysfunction or obstruction
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
EP1744736B1 (de) * 2004-05-14 2009-11-18 Alcon, Inc. Methode zur behandlung trockener augen und uveitis
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WO2006022291A1 (ja) * 2004-08-27 2006-03-02 Senju Pharmaceutical Co, .Ltd. ドライアイ治療用点眼液
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JP5421272B2 (ja) * 2007-10-12 2014-02-19 リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド 眼病治療のための組成物及び方法
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Also Published As

Publication number Publication date
CA2234367C (en) 2002-06-04
HK1013194A1 (en) 1999-08-20
US5696166A (en) 1997-12-09
DE69611251T2 (de) 2001-04-05
WO1997016179A1 (en) 1997-05-09
DK0858330T3 (da) 2001-01-02
GR3035438T3 (en) 2001-05-31
CA2234367A1 (en) 1997-05-09
AU706373B2 (en) 1999-06-17
ATE198044T1 (de) 2000-12-15
AU6851696A (en) 1997-05-22
EP0858330A1 (de) 1998-08-19
JPH11515024A (ja) 1999-12-21
ES2152556T3 (es) 2001-02-01
PT858330E (pt) 2001-03-30
EP0858330B1 (de) 2000-12-13

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