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DE69531502D1 - Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen - Google Patents

Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen

Info

Publication number
DE69531502D1
DE69531502D1 DE69531502T DE69531502T DE69531502D1 DE 69531502 D1 DE69531502 D1 DE 69531502D1 DE 69531502 T DE69531502 T DE 69531502T DE 69531502 T DE69531502 T DE 69531502T DE 69531502 D1 DE69531502 D1 DE 69531502D1
Authority
DE
Germany
Prior art keywords
monoamide
diamide
containing metal
sup
thiol containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69531502T
Other languages
English (en)
Other versions
DE69531502T2 (de
Inventor
William Mcbride
T Dean
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22962421&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69531502(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Diatide Inc filed Critical Diatide Inc
Application granted granted Critical
Publication of DE69531502D1 publication Critical patent/DE69531502D1/de
Publication of DE69531502T2 publication Critical patent/DE69531502T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Solid Fuels And Fuel-Associated Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Sealing Material Composition (AREA)
DE69531502T 1994-06-03 1995-06-01 Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen Expired - Fee Related DE69531502T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US253973 1994-06-03
US08/253,973 US7238340B1 (en) 1991-11-27 1994-06-03 Monoamine, diamide, thiol-containing metal chelating agents
PCT/US1995/006914 WO1995033497A1 (en) 1994-06-03 1995-06-01 Monoamine, diamide, thiol-containing metal chelating agents

Publications (2)

Publication Number Publication Date
DE69531502D1 true DE69531502D1 (de) 2003-09-18
DE69531502T2 DE69531502T2 (de) 2004-06-24

Family

ID=22962421

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69531502T Expired - Fee Related DE69531502T2 (de) 1994-06-03 1995-06-01 Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen

Country Status (14)

Country Link
US (2) US7238340B1 (de)
EP (1) EP0804252B1 (de)
JP (1) JP3727342B2 (de)
KR (1) KR100235137B1 (de)
CN (1) CN1093424C (de)
AT (1) ATE246939T1 (de)
BR (1) BR9507917A (de)
CA (1) CA2191951C (de)
DE (1) DE69531502T2 (de)
DK (1) DK0804252T3 (de)
ES (1) ES2204954T3 (de)
PT (1) PT804252E (de)
WO (1) WO1995033497A1 (de)
ZA (1) ZA954548B (de)

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US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
ES2141102T3 (es) * 1991-02-08 2000-03-16 Diatide Inc Polipeptidos marcados con tecnecio-99m para la generacion de imagenes.
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
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CA2257856A1 (en) * 1996-06-10 1997-12-18 G.D. Searle & Co. Radiopharmaceutical compositions capable of localizing at sites of thrombus
US6083480A (en) 1997-05-01 2000-07-04 Diatide, Inc. Calcitonin receptor binding reagents
US6334996B1 (en) 1997-12-24 2002-01-01 Resolution Pharmaceuticals Inc. Chelators that predominantely form a single stereoisomeric species upon coordination to a metal center
ATE374206T1 (de) * 1997-12-24 2007-10-15 Bracco Int Bv Peptide chelatoren die nach der koordination mit einem metall zu einem vorherrschenden einzel- stereoisomeren führen
US6358491B1 (en) * 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
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US7906103B2 (en) * 2000-03-08 2011-03-15 Gerhard Graupner Methods and compositions for targeted drug delivery
US7122172B1 (en) 2000-03-08 2006-10-17 Gerhart Graupner Methods and compositions for targeted drug delivery
US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
AU2002327180A1 (en) * 2001-06-04 2003-01-21 The General Hospital Corporation Detection and therapy of vulnerable plaque with photodynamic compounds
JP2005507244A (ja) * 2001-08-10 2005-03-17 ノバルティス アクチエンゲゼルシャフト アテローム硬化性病変に結合するペプチド
US7943577B2 (en) * 2001-11-20 2011-05-17 Albany Medical College Alpha-fetoprotein peptides and uses thereof
US7220402B1 (en) * 2001-11-20 2007-05-22 Ordway Research Institute, Inc. Alpha-fetoprotein peptides and uses for imaging
US7199255B2 (en) 2001-12-18 2007-04-03 Univation Technologies, Llc Imino-amide catalysts for olefin polymerization
US6864205B2 (en) 2001-12-18 2005-03-08 Univation Technologies, Llc Heterocyclic-amide catalyst compositions for the polymerization of olefins
US7001863B2 (en) 2001-12-18 2006-02-21 Univation Technologies, Llc Monoamide based catalyst compositions for the polymerization of olefins
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AU2003259172A1 (en) * 2002-07-24 2004-02-09 The Salk Institute For Biological Studies Receptor (sstr4)- selective somatostatin analogs
WO2006049599A1 (en) * 2004-10-28 2006-05-11 The General Hospital Corporation Methods of detection and therapy for atheromatous plaques using immune modulation
US20080260650A1 (en) * 2004-10-28 2008-10-23 The General Hospital Corporation Methods of Detection and Therapy of Inflamed Tissues Using Immune Modulation
US7560227B2 (en) * 2005-02-28 2009-07-14 University Of Massachusetts Biomarkers of vulnerable atherosclerotic plaques and methods of use
WO2006114324A1 (en) * 2005-04-28 2006-11-02 Schering Ag Compounds comprising cyclized somatostatin receptor binding peptides
EP1717247A1 (de) * 2005-04-28 2006-11-02 Schering AG Zyklische Peptide, die sich am Somatostatinrezeptor binden
US7874975B2 (en) * 2005-07-20 2011-01-25 Clear Vascular, Inc. Methods and compositions for treating luminal inflammatory disease
US9623129B2 (en) * 2005-09-26 2017-04-18 Snip Holdings, Inc. Methods and therapies for treating inflammatory conditions with exposed collagen
US8691761B2 (en) * 2006-10-16 2014-04-08 Jean E. F. Rivier Somatostatin receptor 2 antagonists
ES2526292T3 (es) * 2006-10-16 2015-01-09 The Salk Institute For Biological Studies Antagonistas de la somatostatina selectivos para receptor (SSTR2)
US20100196264A1 (en) * 2007-05-18 2010-08-05 The Brigham And Women's Hospital, Inc. Use of somatostatin analogs in myocardial perfusion imaging
CN102088991A (zh) 2008-05-13 2011-06-08 堪萨斯大学 金属提取肽标签和相关方法
JP5604680B2 (ja) * 2009-04-28 2014-10-15 国立大学法人 千葉大学 放射性標識薬剤
WO2011107870A2 (en) * 2010-03-05 2011-09-09 Mahesh Kandula Compounds and compositions and their use in the treatment of diseases related to copper retention
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity

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Also Published As

Publication number Publication date
CN1093424C (zh) 2002-10-30
BR9507917A (pt) 1997-08-12
PT804252E (pt) 2003-12-31
KR100235137B1 (ko) 1999-12-15
CA2191951C (en) 2009-01-27
JP3727342B2 (ja) 2005-12-14
US7238340B1 (en) 2007-07-03
WO1995033497A1 (en) 1995-12-14
KR970703172A (ko) 1997-07-03
JPH10501531A (ja) 1998-02-10
ATE246939T1 (de) 2003-08-15
DE69531502T2 (de) 2004-06-24
CA2191951A1 (en) 1995-12-14
EP0804252B1 (de) 2003-08-13
ES2204954T3 (es) 2004-05-01
US5976496A (en) 1999-11-02
ZA954548B (en) 1996-03-15
DK0804252T3 (da) 2003-10-06
EP0804252A2 (de) 1997-11-05
CN1158090A (zh) 1997-08-27

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