DE69527355D1 - Herstellung von nukleinsaeurekopien - Google Patents
Herstellung von nukleinsaeurekopienInfo
- Publication number
- DE69527355D1 DE69527355D1 DE69527355T DE69527355T DE69527355D1 DE 69527355 D1 DE69527355 D1 DE 69527355D1 DE 69527355 T DE69527355 T DE 69527355T DE 69527355 T DE69527355 T DE 69527355T DE 69527355 D1 DE69527355 D1 DE 69527355D1
- Authority
- DE
- Germany
- Prior art keywords
- strands
- target
- copy target
- oligonucleotides
- copy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9410804A GB9410804D0 (en) | 1994-05-28 | 1994-05-28 | Producing copies of nucleic acids |
| GBGB9502079.8A GB9502079D0 (en) | 1995-02-02 | 1995-02-02 | Producing copies of nucleic acids |
| PCT/GB1995/001237 WO1995033073A1 (en) | 1994-05-28 | 1995-05-30 | Producing copies of nucleic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69527355D1 true DE69527355D1 (de) | 2002-08-14 |
| DE69527355T2 DE69527355T2 (de) | 2003-03-06 |
Family
ID=26304963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69527355T Expired - Lifetime DE69527355T2 (de) | 1994-05-28 | 1995-05-30 | Herstellung von nukleinsaeurekopien |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5922574A (de) |
| EP (1) | EP0763135B1 (de) |
| JP (1) | JPH10500862A (de) |
| CN (1) | CN1152946A (de) |
| AT (1) | ATE220424T1 (de) |
| AU (1) | AU707391B2 (de) |
| CA (1) | CA2191426A1 (de) |
| DE (1) | DE69527355T2 (de) |
| FI (1) | FI964735A (de) |
| NZ (1) | NZ287118A (de) |
| WO (1) | WO1995033073A1 (de) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| GB9503808D0 (en) * | 1995-02-24 | 1995-04-12 | Univ Nottingham | Detection assay |
| GB2308188A (en) * | 1995-12-14 | 1997-06-18 | Tepnel Medical Ltd | Assaying immobilised nucleic acid by primer extension |
| ATE545710T1 (de) | 1997-04-01 | 2012-03-15 | Illumina Cambridge Ltd | Verfahren zur vervielfältigung von nukleinsäuren |
| GB9707980D0 (en) | 1997-04-21 | 1997-06-11 | Brax Genomics Ltd | Characterising DNA |
| CA2291180A1 (en) | 1997-05-23 | 1998-11-26 | Lynx Therapeutics, Inc. | System and apparatus for sequential processing of analytes |
| JP2001511415A (ja) | 1997-07-22 | 2001-08-14 | ラピジーン，インコーポレイテッド | 固体支持体上に溶液をアレイ化するための装置および方法 |
| JP2001511361A (ja) | 1997-07-22 | 2001-08-14 | ラピジーン，インコーポレイテッド | 核酸アレイ上で行われる増幅および他の酵素反応 |
| US5916776A (en) * | 1997-08-27 | 1999-06-29 | Sarnoff Corporation | Amplification method for a polynucleotide |
| WO1999067641A2 (en) | 1998-06-24 | 1999-12-29 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US20040157256A1 (en) * | 1998-09-17 | 2004-08-12 | Taisho Pharmaceutical Co., Ltd. | Immobilized cDNA libraries |
| AR021833A1 (es) * | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| WO2000058516A2 (en) * | 1999-03-26 | 2000-10-05 | Whitehead Institute For Biomedical Research | Universal arrays |
| DK1471926T3 (da) | 1999-06-01 | 2011-02-28 | Baylor College Medicine | Sammensætninger og fremgangsmåder til terapeutisk anvendelse af en atonal-associeret sekvens |
| AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
| GB2377220B (en) * | 2001-04-02 | 2004-08-25 | Brendan James Hamill | Polynucleotide analysis using combinatorial PCR |
| EP2213292B2 (de) | 2002-02-01 | 2016-06-22 | Life Technologies Corporation | Doppelsträngige Oligonukleotide |
| US20060009409A1 (en) | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
| US20030166282A1 (en) | 2002-02-01 | 2003-09-04 | David Brown | High potency siRNAS for reducing the expression of target genes |
| US7211382B2 (en) * | 2002-04-09 | 2007-05-01 | Orchid Cellmark Inc. | Primer extension using modified nucleotides |
| EP1636561B1 (de) | 2002-07-15 | 2011-02-09 | Board Of Regents, The University Of Texas System | Screening kombinatorischer proteinbibliotheken mittels periplasmatischer expression |
| CN1754002B (zh) | 2002-08-12 | 2010-09-08 | 杰能斯有限公司 | 涉及痘病毒和癌的组合物及制备方法 |
| JP4871722B2 (ja) | 2003-07-25 | 2012-02-08 | アプライド バイオシステムズ リミテッド ライアビリティー カンパニー | 固定試料からｒｎａを調製するための方法および組成物 |
| US20050059024A1 (en) | 2003-07-25 | 2005-03-17 | Ambion, Inc. | Methods and compositions for isolating small RNA molecules |
| JP4933435B2 (ja) | 2004-09-14 | 2012-05-16 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド，ア・ボディー・コーポレイト | 遺伝子ターゲティングに基づくブシンドロール処置方法 |
| GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
| GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
| US8980246B2 (en) | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
| CA2621982C (en) * | 2005-09-07 | 2017-11-28 | Jennerex Biotherapeutics Ulc | Systemic treatment of metastatic and/or systemically-disseminated cancers using gm-csf-expressing poxviruses |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| GB0524069D0 (en) | 2005-11-25 | 2006-01-04 | Solexa Ltd | Preparation of templates for solid phase amplification |
| EP2368570A3 (de) | 2006-01-18 | 2012-05-02 | University Of Chicago | Zusammensetzungen und Verfahren in Verbindung mit Stayphylokokken-Bakterienproteinen |
| EP1987159B2 (de) | 2006-02-08 | 2020-08-12 | Illumina Cambridge Limited | Verfahren zur sequenzierung einer polynukleotidmatrize |
| JP5606067B2 (ja) | 2006-09-15 | 2014-10-15 | オタワ ホスピタル リサーチ インスティテュート | 腫瘍崩壊性ラブドウイルス |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| EP2102239B1 (de) | 2006-11-30 | 2012-04-25 | Research Development Foundation | Verbesserte immunglobulin-bibliotheken |
| WO2008093098A2 (en) | 2007-02-02 | 2008-08-07 | Illumina Cambridge Limited | Methods for indexing samples and sequencing multiple nucleotide templates |
| WO2008137475A2 (en) | 2007-05-01 | 2008-11-13 | Research Development Foundation | Immunoglobulin fc libraries |
| EP2191011B1 (de) * | 2007-08-29 | 2017-03-29 | Illumina Cambridge Limited | Verfahren zur sequenzierung einer polynukleotidmatrize |
| US12060554B2 (en) | 2008-03-10 | 2024-08-13 | Illumina, Inc. | Method for selecting and amplifying polynucleotides |
| WO2010038042A1 (en) | 2008-10-02 | 2010-04-08 | Illumina Cambridge Ltd. | Nucleic acid sample enrichment for sequencing applications |
| US20110262477A1 (en) | 2008-10-06 | 2011-10-27 | University Of Chicago | Compositions and Methods Related to Bacterial EAP, EMP, and/or ADSA Proteins |
| WO2011127032A1 (en) | 2010-04-05 | 2011-10-13 | University Of Chicago | Compositions and methods related to protein a (spa) antibodies as an enhancer of immune response |
| KR101773368B1 (ko) | 2009-04-03 | 2017-08-31 | 유니버시티 오브 시카고 | 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법 |
| US9587270B2 (en) | 2009-06-29 | 2017-03-07 | Luminex Corporation | Chimeric primers with hairpin conformations and methods of using same |
| US9409983B2 (en) | 2009-07-23 | 2016-08-09 | The Board Of Trustess Of The University Of Illinois | Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases |
| CN102597256B (zh) | 2009-08-25 | 2014-12-03 | 伊鲁米那股份有限公司 | 选择和扩增多核苷酸的方法 |
| WO2011032088A1 (en) | 2009-09-11 | 2011-03-17 | Arca Biopharma, Inc. | Polymorphisms in the pde3a gene |
| WO2011032180A1 (en) | 2009-09-14 | 2011-03-17 | Jennerex, Inc. | Oncolytic vaccinia virus combination cancer therapy |
| US8182994B2 (en) | 2009-09-15 | 2012-05-22 | Illumina Cambridge Limited | Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing |
| JP6025255B2 (ja) | 2009-12-10 | 2016-11-16 | ターンストーン リミテッド パートナーシップ | 腫瘍退縮性ラブドウイルス |
| DK2515899T3 (en) | 2009-12-23 | 2016-08-15 | Arca Biopharma Inc | METHODS AND COMPOSITIONS FOR CARDIOVASCULAR DISEASES AND CONDITIONS |
| AU2011274367B2 (en) | 2010-07-02 | 2015-04-23 | The University Of Chicago | Compositions and methods related to protein A (SpA) variants |
| US9095540B2 (en) | 2010-09-09 | 2015-08-04 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens |
| CN103429258B (zh) | 2011-01-04 | 2016-03-09 | 新罗杰公司 | 通过施用溶瘤痘苗病毒生成针对肿瘤抗原的抗体和生成肿瘤特异性补体依赖性细胞毒性 |
| US8952132B2 (en) | 2011-02-07 | 2015-02-10 | Research Development Foundation | Engineered immunoglobulin FC polypeptides |
| CA2828532A1 (en) | 2011-02-28 | 2012-11-22 | University Of Iowa Research Foundation | Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender |
| CA2829300A1 (en) | 2011-03-08 | 2012-09-13 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
| US9085631B2 (en) | 2011-04-08 | 2015-07-21 | Nov Vac APS | Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| CA2872045A1 (en) | 2011-06-08 | 2012-12-13 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Compositions and methods for glioblastoma treatment |
| US10040853B2 (en) | 2011-09-09 | 2018-08-07 | Fred Hutchinson Cancer Research Center | Methods and compositions involving NKG2D inhibitors and cancer |
| EP2766388A1 (de) | 2011-10-12 | 2014-08-20 | Møller, Niels Iversen | Peptide aus campylobacter jejuni und ihre verwendung bei der impfung |
| US20140349858A1 (en) | 2011-12-22 | 2014-11-27 | Ibis Bioscience, Inc. | Amplification of a sequence from a ribonucleic acid |
| US9701959B2 (en) | 2012-02-02 | 2017-07-11 | Invenra Inc. | High throughput screen for biologically active polypeptides |
| BR112014026861A2 (pt) | 2012-04-26 | 2018-05-15 | Univ Chicago | antígenos de estafilococos coagulase e métodos de seu uso |
| US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
| CN105658790A (zh) | 2013-02-21 | 2016-06-08 | 东安大略研究所儿童医院有限公司 | 疫苗组合物 |
| BR112016007391A2 (pt) | 2013-10-03 | 2017-08-01 | Oklahoma Med Res Found | biomarcadores da atividade, da intensidade e da fase aguda da doença lúpus eritematoso sistêmico |
| US20160368952A1 (en) | 2013-12-03 | 2016-12-22 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| US20180169211A1 (en) | 2014-11-13 | 2018-06-21 | Evaxion Biotech Aps | Peptides derived from acinetobacter baumannii and their use in vaccination |
| WO2016086227A2 (en) | 2014-11-26 | 2016-06-02 | The Regents Of The University Of California | Therapeutic compositions comprising transcription factors and methods of making and using the same |
| WO2016113252A2 (en) | 2015-01-12 | 2016-07-21 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting klebsiella pneumoniae |
| WO2016130516A1 (en) | 2015-02-09 | 2016-08-18 | Research Development Foundation | Engineered immunoglobulin fc polypeptides displaying improved complement activation |
| EP3070178B1 (de) | 2015-03-20 | 2020-02-12 | Albert-Ludwigs-Universität Freiburg | Verfahren zur diagnose von brustkrebs |
| WO2017005670A1 (en) | 2015-07-04 | 2017-01-12 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa |
| US10526408B2 (en) | 2015-08-28 | 2020-01-07 | Research Development Foundation | Engineered antibody FC variants |
| WO2017144523A1 (en) | 2016-02-22 | 2017-08-31 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| US11718648B2 (en) | 2017-01-05 | 2023-08-08 | Evaxion Biotech A/S | Vaccines targeting Pseudomonas aeruginosa |
| CA3049778C (en) | 2017-01-26 | 2024-06-18 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
| US12140592B2 (en) | 2017-06-16 | 2024-11-12 | Oklahoma Medical Research Foundation | Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis |
| AU2019360758B2 (en) | 2018-10-18 | 2024-08-08 | Oklahoma Medical Research Foundation | Biomarkers for a Systemic Lupus Erythematosus (SLE) disease activity immune index that characterizes disease activity |
| WO2020083904A1 (en) | 2018-10-22 | 2020-04-30 | Evaxion Biotech Aps | Vaccines targeting m. catharrhalis |
| EP3931206A1 (de) | 2019-02-27 | 2022-01-05 | Evaxion Biotech ApS | Impfstoffe gegen h. influenzae |
| EP3772543B1 (de) | 2019-08-09 | 2023-09-27 | Albert-Ludwigs-Universität Freiburg | Verfahren zur diagnose von brustkrebs |
| WO2021140123A1 (en) | 2020-01-06 | 2021-07-15 | Evaxion Biotech Aps | Vaccines targeting neisseria gonorrhoeae |
| JP2024526293A (ja) | 2021-07-05 | 2024-07-17 | エヴァクシオン・バイオテック・アクティエセルスカブ | 淋菌を標的とするワクチン |
| US20240010742A1 (en) | 2022-06-10 | 2024-01-11 | Research Development Foundation | Engineered fcriib selective igg1 fc variants and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4734363A (en) * | 1984-11-27 | 1988-03-29 | Molecular Diagnostics, Inc. | Large scale production of DNA probes |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| CH663728A5 (fr) * | 1985-06-10 | 1988-01-15 | Battelle Memorial Institute | Procede de purification de substances bioactives par adsorption biospecifique. |
| US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| CA1317535C (en) * | 1987-06-30 | 1993-05-11 | Nanibhushan Dattagupta | Assay of sequences using amplified genes |
| AU2735988A (en) * | 1987-12-21 | 1989-07-13 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| SE8801070D0 (sv) * | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| US5153166A (en) * | 1988-08-18 | 1992-10-06 | Trustees Of At Biochem | Chromatographic stationary supports |
| US5066584A (en) * | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
| GB8827160D0 (en) * | 1988-11-21 | 1988-12-29 | Apothekernes Lab | Detection & quantitative determination of rna & dna |
| DK175170B1 (da) * | 1988-11-29 | 2004-06-21 | Sangtec Molecular Diagnostics | Fremgangsmåde og reagenskombination til bestemmmelse af nukleotidsekvenser |
| CA2004326A1 (en) * | 1988-12-23 | 1990-06-23 | Nanibushan Dattagupta | Assay of sequences using amplified genes |
| IE66572B1 (en) * | 1989-02-13 | 1996-01-24 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| CA2011818A1 (en) * | 1989-03-17 | 1990-09-17 | Fred T. Oakes | Methods for purification, amplification and detection of a nucleic acid |
| US5219727A (en) * | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| EP0519016A1 (de) * | 1990-03-07 | 1992-12-23 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Verfahren zur diagnose der lyme-krankheit |
| EP0745689A3 (de) * | 1990-05-11 | 1996-12-11 | Microprobe Corporation | Teststab für einen Nukleinsäure-Hybridisierungstest |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| CA2055755A1 (en) * | 1990-11-22 | 1992-05-23 | Toshihiko Kishimoto | Method of immobilizing single-stranded dna on carrier at terminal |
| US5437976A (en) * | 1991-08-08 | 1995-08-01 | Arizona Board Of Regents, The University Of Arizona | Multi-domain DNA ligands bound to a solid matrix for protein and nucleic acid affinity chromatography and processing of solid-phase DNA |
| WO1993004199A2 (en) * | 1991-08-20 | 1993-03-04 | Scientific Generics Limited | Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids |
| BR9206705A (pt) * | 1991-11-01 | 1995-11-21 | Adelaide Children S Hospital | Processo de amplificação de fase sólida |
| CA2126748A1 (en) * | 1991-12-24 | 1993-06-25 | Stephen Minter | Manipulating nucleic acid sequences |
| MX9300492A (es) * | 1992-01-29 | 1994-07-29 | Hitachi Chemical Co Ltd | Soporte inmovilizado de nucleotido y metodo para su produccion. |
| AU5298393A (en) * | 1992-10-08 | 1994-05-09 | Regents Of The University Of California, The | Pcr assays to determine the presence and concentration of a target |
| GB9322723D0 (en) * | 1993-11-04 | 1993-12-22 | Tepnel Medical Ltd | Determining nucleic acids |
| US5641658A (en) * | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
-
1995
- 1995-05-30 CN CN95194205A patent/CN1152946A/zh active Pending
- 1995-05-30 WO PCT/GB1995/001237 patent/WO1995033073A1/en active IP Right Grant
- 1995-05-30 AT AT95920168T patent/ATE220424T1/de not_active IP Right Cessation
- 1995-05-30 JP JP8500512A patent/JPH10500862A/ja not_active Ceased
- 1995-05-30 NZ NZ287118A patent/NZ287118A/xx unknown
- 1995-05-30 CA CA002191426A patent/CA2191426A1/en not_active Abandoned
- 1995-05-30 AU AU25728/95A patent/AU707391B2/en not_active Ceased
- 1995-05-30 DE DE69527355T patent/DE69527355T2/de not_active Expired - Lifetime
- 1995-05-30 EP EP95920168A patent/EP0763135B1/de not_active Expired - Lifetime
- 1995-11-22 US US08/562,075 patent/US5922574A/en not_active Expired - Lifetime
-
1996
- 1996-11-27 FI FI964735A patent/FI964735A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1152946A (zh) | 1997-06-25 |
| FI964735A0 (fi) | 1996-11-27 |
| CA2191426A1 (en) | 1995-12-07 |
| AU707391B2 (en) | 1999-07-08 |
| ATE220424T1 (de) | 2002-07-15 |
| EP0763135A1 (de) | 1997-03-19 |
| WO1995033073A1 (en) | 1995-12-07 |
| AU2572895A (en) | 1995-12-21 |
| DE69527355T2 (de) | 2003-03-06 |
| NZ287118A (en) | 1999-01-28 |
| EP0763135B1 (de) | 2002-07-10 |
| JPH10500862A (ja) | 1998-01-27 |
| US5922574A (en) | 1999-07-13 |
| FI964735A (fi) | 1997-01-27 |
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