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DE69502179D1 - Verfahren zur trocknung eines materials aus einer lösung - Google Patents

Verfahren zur trocknung eines materials aus einer lösung

Info

Publication number
DE69502179D1
DE69502179D1 DE69502179T DE69502179T DE69502179D1 DE 69502179 D1 DE69502179 D1 DE 69502179D1 DE 69502179 T DE69502179 T DE 69502179T DE 69502179 T DE69502179 T DE 69502179T DE 69502179 D1 DE69502179 D1 DE 69502179D1
Authority
DE
Germany
Prior art keywords
chamber
solution
pressure
pct
frozen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69502179T
Other languages
English (en)
Inventor
Michael Folan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kinerton Ltd
Original Assignee
Kinerton Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinerton Ltd filed Critical Kinerton Ltd
Application granted granted Critical
Publication of DE69502179D1 publication Critical patent/DE69502179D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Formation And Processing Of Food Products (AREA)
  • General Preparation And Processing Of Foods (AREA)
DE69502179T 1994-02-09 1995-01-31 Verfahren zur trocknung eines materials aus einer lösung Expired - Lifetime DE69502179D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE940116 1994-02-09
PCT/IE1995/000013 WO1995022036A1 (en) 1994-02-09 1995-01-31 Process for drying a material from solution

Publications (1)

Publication Number Publication Date
DE69502179D1 true DE69502179D1 (de) 1998-05-28

Family

ID=11040293

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69502179T Expired - Lifetime DE69502179D1 (de) 1994-02-09 1995-01-31 Verfahren zur trocknung eines materials aus einer lösung

Country Status (12)

Country Link
US (1) US5727333A (de)
EP (1) EP0742888B1 (de)
JP (1) JPH09508695A (de)
AT (1) ATE165438T1 (de)
AU (1) AU680727B2 (de)
CA (1) CA2182988A1 (de)
DE (1) DE69502179D1 (de)
IL (1) IL112582A0 (de)
NZ (1) NZ279549A (de)
TW (1) TW288985B (de)
WO (1) WO1995022036A1 (de)
ZA (1) ZA95816B (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
NO311164B1 (no) * 1998-06-02 2001-10-22 Leiv Eiriksson Nyfotek As Fremgangsmåte for frysetörking av lösninger
AU773556B2 (en) * 1999-04-05 2004-05-27 Mannkind Corporation Methods for fine powder formation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE19936281C2 (de) * 1999-08-02 2002-04-04 Bayer Ag Verfahren zur Gefriertrocknung
SE9903236D0 (sv) * 1999-09-10 1999-09-10 Astra Ab Method to obtain microparticles
US6284283B1 (en) 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6605438B1 (en) * 2001-03-26 2003-08-12 Louis Dischler Lyophilizing of liquid drops having arbitrary edges and application thereof to microarrays of biological reagents
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
DE10234165B4 (de) * 2002-07-26 2008-01-03 Advanced Micro Devices, Inc., Sunnyvale Verfahren zum Füllen eines Grabens, der in einem Substrat gebildet ist, mit einem isolierenden Material
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
JP4808970B2 (ja) * 2002-12-30 2011-11-02 ネクター セラピューティクス 噴霧乾燥システム
EP1589948A1 (de) * 2003-01-15 2005-11-02 Dow Global Technologies Inc. Arzneimittelpartikel gewonnen durch anfrieren auf eine kalte oberfläche
US6931888B2 (en) 2003-02-07 2005-08-23 Ferro Corporation Lyophilization method and apparatus for producing particles
US7083748B2 (en) * 2003-02-07 2006-08-01 Ferro Corporation Method and apparatus for continuous particle production using supercritical fluid
EP1631496B1 (de) * 2003-04-28 2014-02-26 Medical Instill Technologies, Inc. Behälter mit ventilanordnung zum füllen und abgeben von stoffen und vorrichtung und verfahren zum füllen
US20060008531A1 (en) * 2003-05-08 2006-01-12 Ferro Corporation Method for producing solid-lipid composite drug particles
JP5183068B2 (ja) * 2003-12-22 2013-04-17 フィンレイ,ウォーレン,エイチ 大気噴出凍結乾燥法による粉末形成
DK1794524T3 (da) 2004-07-23 2012-04-16 Bayer Technology Services Gmbh Fremgangsmåde til frysning, tørring, lagring, analysering og fyldning (SFD-SAF-fremgangsmåde) (fremgangsmåde til frysetørring af piller til parenterale biologiske lægemidler)
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
CN104324366B (zh) 2005-09-14 2016-10-05 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
US9453675B2 (en) 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material
CN101379357B (zh) * 2006-02-10 2012-08-29 普莱克斯技术有限公司 冷冻干燥系统和方法
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
WO2007127286A2 (en) * 2006-04-24 2007-11-08 Medical Instill Technologies, Inc. Needle penetrable and laser resealable lyophilization device and related method
EP1870649A1 (de) * 2006-06-20 2007-12-26 Octapharma AG Gefriertocknung zum Erzielen einer bestimmte Restfeuchte durch beschränkte Desorptionsenergiepegeln.
EP2107934B1 (de) * 2006-12-07 2019-11-20 FrieslandCampina Nederland B.V. Verfahren und vorrichtung zum sprühtrocknen
US8240065B2 (en) 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
DK2293833T3 (en) 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
JP2012523414A (ja) 2009-04-09 2012-10-04 エンテグリオン、インコーポレイテッド 噴霧乾燥した血液製剤とその製造方法
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
BRPI1011220B1 (pt) 2009-05-29 2020-03-10 Pearl Therapeutics, Inc. Composição farmacêutica administrável a partir de um inalador de dose medida compreendendo um meio de suspensão compreendendo um propelente, duas ou mais espécies diferentes de partículas de agente ativo e uma ou mais espécies de partículas respiráveis em suspensão
SG176738A1 (en) 2009-06-12 2012-01-30 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011035062A2 (en) 2009-09-16 2011-03-24 Velico Medical, Inc. Spray dried human plasma
US8407912B2 (en) * 2010-09-16 2013-04-02 Velico Medical, Inc. Spray dried human plasma
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
US9945611B2 (en) 2010-08-04 2018-04-17 Ima Life North America Inc. Bulk freeze drying using spray freezing and agitated drying
BR112013002675B1 (pt) * 2010-08-04 2020-11-24 Ima Life North America Inc. sistemas e método de liofilização para liofilizar produto a granel
US8966782B2 (en) 2010-09-28 2015-03-03 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
ES2621017T3 (es) 2010-09-28 2017-06-30 Baxter International Inc Optimización de la nucleación y cristalización en la liofilización utilizando una congelación con intersticios
EP2745923A3 (de) 2010-10-29 2014-10-01 Velico Medical, Inc. System und Verfahren zum Sprühtrocknen einer Flüssigkeit
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
US8549768B2 (en) * 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5827178B2 (ja) * 2012-06-05 2015-12-02 北越紀州製紙株式会社 セルロース多孔質体及びその製造方法
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
KR101272785B1 (ko) * 2012-12-18 2013-06-11 포항공과대학교 산학협력단 고속 입자 빔을 이용한 액막 제거 방법
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
CA2905542C (en) 2013-03-15 2022-05-03 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
PL3177359T3 (pl) * 2014-08-04 2020-09-21 F. Hoffmann-La Roche Ag Urządzenie i sposoby do uszczelniania lekarstwa w obrębie medycznego urządzenia dostarczającego
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN106889058B (zh) * 2017-02-20 2019-07-19 徐小杨 一种细胞冻干系统和方法
GB2564481B (en) 2017-07-14 2019-10-23 4D Pharma Leon S L U Process
FR3086739B1 (fr) * 2018-09-27 2021-02-12 Maat Pharma Recipient de lyophilisation
US11744257B1 (en) 2018-10-19 2023-09-05 Harvest Right, LLC Freeze-drying methods including vacuum freezing
US20220125078A1 (en) * 2018-10-19 2022-04-28 Harvest Right, LLC Freeze Drying Methods
US12055346B1 (en) * 2021-05-27 2024-08-06 Robert Stumbo Dryer for portable electronic devices
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2471035A (en) * 1943-10-02 1949-05-24 Frank E Hurd Apparatus for the desiccation of organic substances
US3362835A (en) * 1964-01-15 1968-01-09 Fmc Corp Spray freeze drying system
FR1449444A (fr) * 1965-10-09 1966-08-12 Atlas Soc As Procédé de congélation-dessiccation, et appareil pour la mise en oeuvre du procédé
US3319344A (en) * 1965-10-22 1967-05-16 Battelle Development Corp Freeze drying liquid foods
US3313032A (en) * 1966-07-28 1967-04-11 George J Malecki Freeze-drying process and apparatus
US3633283A (en) * 1967-07-06 1972-01-11 Nestle Sa Soc Ass Tech Prod Drying apparatus
FR2016600A1 (en) * 1968-08-29 1970-05-08 Leybold Heraeus Verwaltung Frozen granules for freeze drying
US3616542A (en) * 1969-02-24 1971-11-02 Earl L Rader Apparatus and processes for producing freeze dried products
US3621587A (en) * 1970-08-06 1971-11-23 Smitherm Industries Freeze drying apparatus
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
US3909957A (en) * 1971-07-14 1975-10-07 Arjun Dev Passey Apparatus for freeze-drying
US4033048A (en) * 1976-01-12 1977-07-05 Clayton Van Ike Freeze drying apparatus
DE3105623A1 (de) * 1981-02-16 1982-09-02 Erhard Dipl.-Ing.agr. 8000 München Grolitsch Verfahren zur schonenden gefriertrocknung und pulverisierung von empfindlichen trocknungsguetern wie wasserhaltigen lebensmitteln
US4823478A (en) * 1987-11-30 1989-04-25 Fts Systems, Inc. Freeze dryer for unattended operation
US4848094A (en) * 1988-04-29 1989-07-18 Union Carbide Corporation Droplet freezing method and apparatus
US5257657A (en) * 1990-07-11 1993-11-02 Incre, Inc. Method for producing a free-form solid-phase object from a material in the liquid phase
US5248905A (en) * 1990-12-28 1993-09-28 National Semiconductor Corporation High speed, master/slave latch transceiver having a directly-driven slave stage
US5208998A (en) * 1991-02-25 1993-05-11 Oyler Jr James R Liquid substances freeze-drying systems and methods
DE4113512C2 (de) * 1991-04-25 1995-04-20 Grolitsch Lisbeth Verfahren und Vorrichtung zur Gefriertrocknung und Pulverisierung von Lebensmitteln
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation

Also Published As

Publication number Publication date
AU1671095A (en) 1995-08-29
WO1995022036A1 (en) 1995-08-17
JPH09508695A (ja) 1997-09-02
US5727333A (en) 1998-03-17
TW288985B (de) 1996-10-21
IL112582A0 (en) 1995-05-26
ZA95816B (en) 1995-10-09
EP0742888B1 (de) 1998-04-22
NZ279549A (en) 1996-11-26
EP0742888A1 (de) 1996-11-20
ATE165438T1 (de) 1998-05-15
CA2182988A1 (en) 1995-08-17
AU680727B2 (en) 1997-08-07

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Legal Events

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8332 No legal effect for de