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DE69435215D1 - Perfluorkohlenstoffe als entzündungshemmendes Mittel - Google Patents

Perfluorkohlenstoffe als entzündungshemmendes Mittel

Info

Publication number
DE69435215D1
DE69435215D1 DE69435215T DE69435215T DE69435215D1 DE 69435215 D1 DE69435215 D1 DE 69435215D1 DE 69435215 T DE69435215 T DE 69435215T DE 69435215 T DE69435215 T DE 69435215T DE 69435215 D1 DE69435215 D1 DE 69435215D1
Authority
DE
Germany
Prior art keywords
perfluorocarbons
inflammatory agent
tissue
reducing
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69435215T
Other languages
English (en)
Inventor
Bradley Phillip Fuhrman
Stephen F Flaim
Lynn Joanne Hernan
Frances Darey Nesti
Michele Cecile Papo
David Marc Steinhorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
Research Foundation of State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of State University of New York filed Critical Research Foundation of State University of New York
Application granted granted Critical
Publication of DE69435215D1 publication Critical patent/DE69435215D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69435215T 1993-09-29 1994-09-29 Perfluorkohlenstoffe als entzündungshemmendes Mittel Expired - Fee Related DE69435215D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/128,811 US5470885A (en) 1993-09-29 1993-09-29 Fluorocarbons as anti-inflammatory agents
PCT/US1994/011092 WO1995008985A1 (en) 1993-09-29 1994-09-29 Perfluorocarbons as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
DE69435215D1 true DE69435215D1 (de) 2009-08-20

Family

ID=22437089

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69435215T Expired - Fee Related DE69435215D1 (de) 1993-09-29 1994-09-29 Perfluorkohlenstoffe als entzündungshemmendes Mittel

Country Status (8)

Country Link
US (2) US5470885A (de)
EP (1) EP0738142B1 (de)
JP (1) JPH09503211A (de)
AT (1) ATE435646T1 (de)
AU (1) AU691837B2 (de)
CA (1) CA2172601A1 (de)
DE (1) DE69435215D1 (de)
WO (1) WO1995008985A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0583358T3 (da) * 1991-05-03 1999-08-16 Alliance Pharma Partiel væskerespiration af carbonfluorider
US5470885A (en) * 1993-09-29 1995-11-28 The Research Foundation Of The State University Of New York Fluorocarbons as anti-inflammatory agents
US5861175A (en) * 1996-03-15 1999-01-19 Alliance Pharmaceutical Corp. Use of fluorocarbons for diagnosis and treatment of articular disorders
WO1998016210A1 (en) * 1996-10-15 1998-04-23 Sonus Pharmaceuticals, Inc. Fluorocarbon-containing agents for pulmonary lavage and drug delivery
SE507617C2 (sv) * 1996-12-20 1998-06-29 Siemens Elema Ab Anordning avsedd att användas vid ett behandlingssystem för respiratorvård med vätska
US20060025348A1 (en) * 1997-05-28 2006-02-02 Pilon Aprile L Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
US6255281B1 (en) * 1997-05-28 2001-07-03 Claragen, Inc. And U.S. Government Use of recombinant human uteroglobin in treatment of inflammatory and fibrotic conditions
US20060281681A1 (en) * 1997-05-28 2006-12-14 Pilon Aprile L Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
DE19823606C2 (de) * 1998-05-27 2002-02-28 Draeger Medical Ag Verwendung von Perfluorcarbone in einem Atemgasgemisch sowie die Vorrichtung
US6894079B1 (en) 1998-12-01 2005-05-17 Alexandre T. Rotta Method for reducing free-radical induced injury
ES2160534B1 (es) * 1999-12-30 2002-04-16 Vita Invest Sa Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil) fenilo.
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US6235796B1 (en) * 2000-06-26 2001-05-22 Sarfaraz K. Niazi Use of fluorocarbons for the prevention of surgical adhesions
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
CA2468958C (en) 2001-12-19 2012-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
JP4079257B2 (ja) * 2002-10-01 2008-04-23 株式会社リコー 静電荷像現像用トナー
US20050118108A1 (en) * 2003-11-28 2005-06-02 Cowan Ada S. Pulmonary delivery of a liquid medicament aerosol
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
US7566743B2 (en) * 2005-11-18 2009-07-28 Mark Glazman System and method for medical treatment
US8454938B2 (en) * 2005-12-21 2013-06-04 Solaeromed Inc. Treatment of respiratory diseases
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
BRPI0911945A2 (pt) 2008-05-13 2015-10-13 Clarassance Inc cc10 humana recombinante e suas composições para uso no tratamento de rinite nasal
EP2398500B1 (de) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Arzneiabgabesystem auf glutathion-basis
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
NZ599511A (en) 2009-10-15 2014-06-27 Clarassance Inc Recombinant human cc10 protein for treatment of influenza
US9168285B2 (en) 2009-10-15 2015-10-27 Therabron Therapeutics, Inc. Recombinant human CC10 protein for treatment of influenza and ebola
JP2011246396A (ja) * 2010-05-27 2011-12-08 Shiseido Co Ltd 血流促進剤および外用剤
EP2587917A4 (de) * 2010-07-01 2015-05-06 Mtm Res Llc Fluorchemische antifibroblasten-emulsionstherapien
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2023039605A1 (en) * 2021-09-13 2023-03-16 The Board Of Regents Of The University Of Texas System Systemic injection of superheated perfluorocarbon emulsion to improve ventilation and reduce ventilator-induced lung injury

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044121A (en) * 1976-03-11 1977-08-23 Minnesota Mining And Manufacturing Company Hair spray containing fluorocarbon compounds as additives
US4680173A (en) * 1977-04-28 1987-07-14 Norman D. Burger Aerosol dispensing system
US4490351A (en) * 1982-03-15 1984-12-25 Children's Hospital Medical Center Methods of treating disorders of an eye with liquid perfluorocarbons
US4543202A (en) * 1984-03-23 1985-09-24 E. I. Du Pont De Nemours And Company Aerosol propellant compositions
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5284645A (en) * 1987-08-05 1994-02-08 Alliance Pharmaceutical Corp. Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems
US4927623A (en) * 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
AU2807689A (en) * 1986-09-19 1989-03-01 Chemex Pharmaceuticals Inc. Method for the treatment of body tissues and the administration of drugs thereto
US4897262A (en) * 1988-03-22 1990-01-30 Playtex Jhirmack, Inc. Non-aerosol hair spray composition
US5028428A (en) * 1988-08-09 1991-07-02 Estee Lauder Inc. Anti-irritant and desensitizing compositions and methods of their use
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5213570A (en) * 1990-12-14 1993-05-25 Mallinckrodt Medical, Inc. System and method for oxygenation of the pericardium
WO1992019244A2 (en) * 1991-05-01 1992-11-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine A method for treating infectious respiratory diseases
US5437272A (en) * 1991-05-01 1995-08-01 Alliance Pharmaceutical Corp. Perfluorocarbon associated gas exchange
DK0583358T3 (da) * 1991-05-03 1999-08-16 Alliance Pharma Partiel væskerespiration af carbonfluorider
US5470885A (en) * 1993-09-29 1995-11-28 The Research Foundation Of The State University Of New York Fluorocarbons as anti-inflammatory agents

Also Published As

Publication number Publication date
CA2172601A1 (en) 1995-04-06
EP0738142B1 (de) 2009-07-08
JPH09503211A (ja) 1997-03-31
ATE435646T1 (de) 2009-07-15
AU7846994A (en) 1995-04-18
US5733939A (en) 1998-03-31
AU691837B2 (en) 1998-05-28
EP0738142A1 (de) 1996-10-23
WO1995008985A1 (en) 1995-04-06
EP0738142A4 (de) 1997-07-16
US5470885A (en) 1995-11-28

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee