Nothing Special   »   [go: up one dir, main page]

DE60310748D1 - Verfahren zur homogenen masskultivierung von t-lymphozyten - Google Patents

Verfahren zur homogenen masskultivierung von t-lymphozyten

Info

Publication number
DE60310748D1
DE60310748D1 DE60310748T DE60310748T DE60310748D1 DE 60310748 D1 DE60310748 D1 DE 60310748D1 DE 60310748 T DE60310748 T DE 60310748T DE 60310748 T DE60310748 T DE 60310748T DE 60310748 D1 DE60310748 D1 DE 60310748D1
Authority
DE
Germany
Prior art keywords
lymphocytes
homogeneous mass
mass cultivation
refers
lymphocytic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310748T
Other languages
English (en)
Other versions
DE60310748T2 (de
Inventor
Silvia Trasciatti
Luisa Nolli
Luigi Cavenaghi
Bernardi Nadia De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abiogen Pharma SRL
Original Assignee
Abiogen Pharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma SRL filed Critical Abiogen Pharma SRL
Publication of DE60310748D1 publication Critical patent/DE60310748D1/de
Application granted granted Critical
Publication of DE60310748T2 publication Critical patent/DE60310748T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE60310748T 2002-10-04 2003-10-06 Verfahren zur kultivierung von t-lymphozyten in grossem massstab in einem homogenen system Expired - Lifetime DE60310748T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT002118A ITMI20022118A1 (it) 2002-10-04 2002-10-04 Procedimento per la coltura su larga scala di t-linfociti in un sistema omogeneo.
ITMI20022118 2002-10-04
PCT/EP2003/011024 WO2004031370A1 (en) 2002-10-04 2003-10-06 Procedure for the large-scale t-lymphocytes culture in a homogeneous system

Publications (2)

Publication Number Publication Date
DE60310748D1 true DE60310748D1 (de) 2007-02-08
DE60310748T2 DE60310748T2 (de) 2007-10-11

Family

ID=32051228

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310748T Expired - Lifetime DE60310748T2 (de) 2002-10-04 2003-10-06 Verfahren zur kultivierung von t-lymphozyten in grossem massstab in einem homogenen system

Country Status (15)

Country Link
US (1) US7678571B2 (de)
EP (1) EP1554374B1 (de)
JP (1) JP2006500936A (de)
CN (1) CN100535107C (de)
AT (1) ATE349513T1 (de)
AU (1) AU2003286134B2 (de)
CA (1) CA2500408C (de)
DE (1) DE60310748T2 (de)
DK (1) DK1554374T3 (de)
ES (1) ES2279190T3 (de)
HK (1) HK1076294A1 (de)
IT (1) ITMI20022118A1 (de)
PT (1) PT1554374E (de)
SI (1) SI1554374T1 (de)
WO (1) WO2004031370A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101302491B (zh) * 2007-05-09 2011-09-14 王歈 高效扩增活化淋巴细胞的方法和培养系统
IL266209B1 (en) 2016-10-26 2024-10-01 Iovance Biotherapeutics Inc Restimulation of cryopreserved sputum infiltrates lymphocytes
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
EP3635097A1 (de) 2017-06-05 2020-04-15 Iovance Biotherapeutics, Inc. Verfahren zur verwendung von tumorinfiltrierenden lymphozyten in einem doppeltrefraktären melanom
US11713446B2 (en) 2018-01-08 2023-08-01 Iovance Biotherapeutics, Inc. Processes for generating TIL products enriched for tumor antigen-specific T-cells
CA3087771A1 (en) 2018-01-08 2019-07-11 Iovance Biotherapeutics, Inc. Processes for generating til products enriched for tumor antigen-specific t-cells
AU2019257749A1 (en) 2018-04-27 2020-10-22 Iovance Biotherapeutics, Inc. Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2023201369A1 (en) 2022-04-15 2023-10-19 Iovance Biotherapeutics, Inc. Til expansion processes using specific cytokine combinations and/or akti treatment
CN115558641B (zh) * 2022-11-14 2023-05-12 四川新生命干细胞科技股份有限公司 高纯度效应免疫细胞群及其培养方法、试剂组合物和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026284A1 (en) * 1993-05-14 1994-11-24 The Wistar Institute Of Anatomy And Biology Use of modified tall-104 cells to treat cancer and viral diseases
EP0652891A1 (de) * 1992-06-05 1995-05-17 Synergen, Inc. AUS T-ZELLEN MONOZYTEN INDUZIERENDE PROTEINE (TMIPs)
US5789147A (en) * 1994-12-05 1998-08-04 New York Blood Center, Inc. Method for concentrating white cells from whole blood by adding a red cell sedimentation reagent to whole anticoagulated blood
US6022344A (en) * 1997-12-04 2000-02-08 Npbi International B.V. Cryopreservation bag

Also Published As

Publication number Publication date
US20060034802A1 (en) 2006-02-16
EP1554374B1 (de) 2006-12-27
PT1554374E (pt) 2007-03-30
CA2500408C (en) 2015-02-17
JP2006500936A (ja) 2006-01-12
HK1076294A1 (en) 2006-01-13
AU2003286134A1 (en) 2004-04-23
CN1703506A (zh) 2005-11-30
ATE349513T1 (de) 2007-01-15
ES2279190T3 (es) 2007-08-16
DK1554374T3 (da) 2007-05-07
CA2500408A1 (en) 2004-04-15
DE60310748T2 (de) 2007-10-11
SI1554374T1 (sl) 2007-06-30
CN100535107C (zh) 2009-09-02
EP1554374A1 (de) 2005-07-20
WO2004031370A1 (en) 2004-04-15
ITMI20022118A1 (it) 2004-04-05
AU2003286134B2 (en) 2008-10-16
US7678571B2 (en) 2010-03-16

Similar Documents

Publication Publication Date Title
DE60238863D1 (de) Vorrichtung und verfahren zur fermentation in hohen zelldichten
ATE365793T1 (de) Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe
DK1664318T3 (da) L-aminosyre-producerende mikroorganisme og fremgangsmåde til fremstilling af L-aminosyre
DE60323340D1 (de) Verfahren zur herstellung interferierender rna-moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
ATE452664T1 (de) Verfahren und vorrichtung zum züchten von zellen
MX2007005132A (es) Medios libres de proteina animal para cultivo de celulas.
BR122019022434B8 (pt) método para cultivar células de mamífero que secretam proteína heteróloga em um sobrenadante de cultura celular
SG158025A1 (en) Growth medium c. histolyticum without ingredients of mamalian sources
SE0850111L (sv) Förfarande för differentiering av stamceller till celler av den endodermala och pankreatiska utvecklingslinjen
NO20072719L (no) Serumfritt cellekulturmedium for pattedyrceller
ATE414144T1 (de) Kulturen von e1-immortalisierten zellen und verfahren zu deren kultivierung zur erhöhung der produktausbeuten davon
ATE349513T1 (de) Verfahren zur homogenen masskultivierung von t- lymphozyten
DE60307615D1 (de) Zellkulturmedium
EA201000901A1 (ru) Способ культивирования микроорганизмов, относящихся к порядку thraustochytriales
EP1506005A4 (de) Verfahren für die kultur von sporozoea sp. in vitro und ihre anwendungen
MX2012007117A (es) Metodo para cultivar celulas adherentes.
DE50312554D1 (de) Verfahren zur kultivierung von zellen zur produktion von substanzen
EA200702050A1 (ru) Способ микробиального производства ценного соединения
DK1517987T3 (da) Bomuldsrottelungeceller til virusdyrkning
ATE384121T1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
ATE313622T1 (de) Verfahren zur züchtung von haftenden tierischen zellen
ATE334209T1 (de) Inaktivierung von genen des mep-wegs
DE10393303D2 (de) Kultursysteme zur sterilen kontinuierlichen Kultivierung von Zellen
ATE461994T1 (de) Verfahren und vorrichtungen zum kultivieren von stammzellen
DE502005001971D1 (de) Verfahren zur herstellung von rekombinanten proteinen in eukaryontischen wirtszellen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition