DE60234369D1 - Manipulierte matrizen und ihre verwendung bei der single-primer-amplifikation - Google Patents
Manipulierte matrizen und ihre verwendung bei der single-primer-amplifikationInfo
- Publication number
- DE60234369D1 DE60234369D1 DE60234369T DE60234369T DE60234369D1 DE 60234369 D1 DE60234369 D1 DE 60234369D1 DE 60234369 T DE60234369 T DE 60234369T DE 60234369 T DE60234369 T DE 60234369T DE 60234369 D1 DE60234369 D1 DE 60234369D1
- Authority
- DE
- Germany
- Prior art keywords
- polynucleotide
- template
- primer
- anneals
- predetermined sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Control Of Amplification And Gain Control (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Saccharide Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32345501P | 2001-09-19 | 2001-09-19 | |
| PCT/US2002/029889 WO2003025202A2 (en) | 2001-09-19 | 2002-09-19 | Engineered templates and their use in single primer amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60234369D1 true DE60234369D1 (de) | 2009-12-24 |
Family
ID=23259271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60234369T Expired - Lifetime DE60234369D1 (de) | 2001-09-19 | 2002-09-19 | Manipulierte matrizen und ihre verwendung bei der single-primer-amplifikation |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7306906B2 (de) |
| EP (1) | EP1436404B1 (de) |
| JP (2) | JP4439262B2 (de) |
| AT (1) | ATE448320T1 (de) |
| AU (1) | AU2002341752B2 (de) |
| CA (1) | CA2460639C (de) |
| CY (1) | CY1109828T1 (de) |
| DE (1) | DE60234369D1 (de) |
| DK (1) | DK1436404T3 (de) |
| ES (1) | ES2336433T3 (de) |
| PT (1) | PT1436404E (de) |
| WO (1) | WO2003025202A2 (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057651A1 (en) | 2000-12-08 | 2006-03-16 | Bowdish Katherine S | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| US9249229B2 (en) | 2000-12-08 | 2016-02-02 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| EP1341902A2 (de) | 2000-12-08 | 2003-09-10 | Alexion Pharmaceuticals, Inc. | Chronische lymphozytäre leukämiezelllinie und deren verwendung zur herstellung eines antikörpers |
| US7408041B2 (en) | 2000-12-08 | 2008-08-05 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| AU2002230734A1 (en) * | 2000-12-11 | 2002-06-24 | Alexion Pharmaceuticals, Inc. | Nested oligonucleotides containing hairpin for nucleic acid amplification |
| US7393656B2 (en) | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
| US7414111B2 (en) * | 2001-09-19 | 2008-08-19 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
| US7593483B2 (en) * | 2004-05-07 | 2009-09-22 | Broadcom Corporation | Nonlinear mapping in digital-to-analog and analog-to-digital converters |
| EP2290076B1 (de) | 2004-05-28 | 2015-03-25 | Asuragen, Inc. | Verfahren und Zusammensetzungen mit MicroRNA |
| US20060078894A1 (en) * | 2004-10-12 | 2006-04-13 | Winkler Matthew M | Methods and compositions for analyzing nucleic acids |
| ES2507544T3 (es) | 2004-11-12 | 2014-10-15 | Asuragen, Inc. | Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN |
| JP2009506788A (ja) * | 2005-09-06 | 2009-02-19 | ジェン−プローブ・インコーポレーテッド | 核酸の等温増幅のための方法、組成物及びキット |
| ES2586825T3 (es) | 2006-01-12 | 2016-10-19 | Alexion Pharmaceuticals, Inc. | Anticuerpos para OX-2/CD200 y usos de los mismos |
| WO2007130967A2 (en) | 2006-05-01 | 2007-11-15 | Siemens Healthcare Diagnostics Inc. | Novel oligonucleotide primers and methods for dna replication |
| EP2145001A2 (de) * | 2006-09-19 | 2010-01-20 | Asuragen, Inc. | Von mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p regulierte gene und stoffwechselwege als ziele für einen therapeutischen eingriff |
| US20080131878A1 (en) * | 2006-12-05 | 2008-06-05 | Asuragen, Inc. | Compositions and Methods for the Detection of Small RNA |
| EP2104735A2 (de) * | 2006-12-08 | 2009-09-30 | Asuragen, INC. | Mir-21-regulierte gene und pfade als ziele für therapeutische interventionen |
| CN101622348A (zh) * | 2006-12-08 | 2010-01-06 | 奥斯瑞根公司 | 作为治疗性干预靶标的miR-20调节的基因和途径 |
| CA2671194A1 (en) * | 2006-12-08 | 2008-06-19 | Asuragen, Inc. | Mir-20 regulated genes and pathways as targets for therapeutic intervention |
| DK2104737T3 (da) * | 2006-12-08 | 2013-05-27 | Asuragen Inc | Funktioner og formål for let-7 mikro-RNAer |
| US20090175827A1 (en) * | 2006-12-29 | 2009-07-09 | Byrom Mike W | miR-16 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
| US20090232893A1 (en) * | 2007-05-22 | 2009-09-17 | Bader Andreas G | miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
| AU2008261951A1 (en) * | 2007-06-08 | 2008-12-18 | Asuragen, Inc. | miR-34 regulated genes and pathways as targets for therapeutic intervention |
| EP2185593B1 (de) | 2007-07-25 | 2017-12-13 | Alexion Pharmaceuticals, Inc. | Zusammensetzungen zur behandlung von autoimmunkrankheit |
| WO2009036332A1 (en) | 2007-09-14 | 2009-03-19 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
| US20090186015A1 (en) * | 2007-10-18 | 2009-07-23 | Latham Gary J | Micrornas differentially expressed in lung diseases and uses thereof |
| WO2009070805A2 (en) * | 2007-12-01 | 2009-06-04 | Asuragen, Inc. | Mir-124 regulated genes and pathways as targets for therapeutic intervention |
| US20090192114A1 (en) * | 2007-12-21 | 2009-07-30 | Dmitriy Ovcharenko | miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention |
| EP4450642A2 (de) | 2008-01-17 | 2024-10-23 | Sequenom, Inc. | Einzelmolekülnukleinsäurensequenzanalyseverfahren und zusammensetzungen |
| US20090263803A1 (en) * | 2008-02-08 | 2009-10-22 | Sylvie Beaudenon | Mirnas differentially expressed in lymph nodes from cancer patients |
| WO2009154835A2 (en) * | 2008-03-26 | 2009-12-23 | Asuragen, Inc. | Compositions and methods related to mir-16 and therapy of prostate cancer |
| US20090258928A1 (en) * | 2008-04-08 | 2009-10-15 | Asuragen, Inc. | Methods and compositions for diagnosing and modulating human papillomavirus (hpv) |
| EP2990487A1 (de) | 2008-05-08 | 2016-03-02 | Asuragen, INC. | Zusammensetzungen und verfahren in zusammenhang mit der mirna-modulation von neovaskularisation oder angiogenese |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| WO2010053587A2 (en) * | 2008-11-07 | 2010-05-14 | Mlc Dx Incorporated | Methods of monitoring conditions by sequence analysis |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| WO2010056737A2 (en) * | 2008-11-11 | 2010-05-20 | Mirna Therapeutics, Inc. | Methods and compositions involving mirnas in cancer stem cells |
| DK3059337T3 (da) | 2009-01-15 | 2019-07-22 | Adaptive Biotechnologies Corp | Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier |
| CN102459643B (zh) | 2009-06-25 | 2016-06-01 | 弗雷德哈钦森癌症研究中心 | 检测获得性免疫的方法 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| EP2621950A4 (de) * | 2010-09-27 | 2015-09-02 | Janssen Biotech Inc | Antikörper zur bindung von humanem kollagen ii |
| US8906649B2 (en) | 2010-09-27 | 2014-12-09 | Janssen Biotech, Inc. | Antibodies binding human collagen II |
| CA2826043A1 (en) | 2011-02-03 | 2012-08-09 | Mirna Therapeutics, Inc. | Synthetic mimics of mir-124 |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| US9644241B2 (en) | 2011-09-13 | 2017-05-09 | Interpace Diagnostics, Llc | Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease |
| US9279159B2 (en) | 2011-10-21 | 2016-03-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| EP3388535B1 (de) | 2011-12-09 | 2021-03-24 | Adaptive Biotechnologies Corporation | Diagnose von lymphoid-malignomen und nachweis von minimaler resterkrankung |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| EP2823060B1 (de) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Festlegung von gepaarten immunrezeptorketten aus frequenzabgestimmten untereinheiten |
| CN104520440B (zh) | 2012-05-08 | 2017-10-03 | 适应生物技术公司 | 用于测量和校准多重pcr反应中的扩增偏倚的组合物和方法 |
| AR091649A1 (es) | 2012-07-02 | 2015-02-18 | Bristol Myers Squibb Co | Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos |
| ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
| CA2892818A1 (en) * | 2012-11-28 | 2014-06-05 | Abwiz Bio, Inc. | Preparation of gene-specific templates for the use in single primer amplification |
| WO2014144495A1 (en) | 2013-03-15 | 2014-09-18 | Abvitro, Inc. | Single cell bar-coding for antibody discovery |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| DK3508502T5 (da) | 2013-09-20 | 2024-09-02 | Bristol Myers Squibb Co | Kombination af anti-lag-3-antistoffer og anti-pd-1-antistoffer til behandling af tumorer |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| AU2015227054A1 (en) | 2014-03-05 | 2016-09-22 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| WO2015138920A1 (en) | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| EP3212790B1 (de) | 2014-10-29 | 2020-03-25 | Adaptive Biotechnologies Corp. | Hochmultiplexierter gleichzeitiger nachweis von für adaptive gepaarte immunrezeptorheterodimere codierenden nukleinsäuren aus einer vielzahl von proben |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| CA2968543C (en) | 2014-11-25 | 2024-04-02 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| EP3591074B1 (de) | 2015-02-24 | 2024-10-23 | Adaptive Biotechnologies Corp. | Verfahren zur diagnose einer infektionskrankheit und bestimmung des hla-status mittels immunrepertoiresequenzierung |
| EP3277294B1 (de) | 2015-04-01 | 2024-05-15 | Adaptive Biotechnologies Corp. | Verfahren zur identifizierung von menschlichen kompatiblen t-zell-rezeptoren spezifisch für ein antigen-ziel |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| US11723975B2 (en) | 2017-05-30 | 2023-08-15 | Bristol-Myers Squibb Company | Compositions comprising an anti-LAG-3 antibody or an anti-LAG-3 antibody and an anti-PD-1 or anti-PD-L1 antibody |
| SI3631454T1 (sl) | 2017-05-30 | 2023-12-29 | Bristol-Myers Squibb Company | Zdravljenje lag-3 pozitivnih tumorjev |
| US11761963B2 (en) | 2017-09-27 | 2023-09-19 | Alexion Pharmaceuticals, Inc. | Biomarker signature for predicting tumor response to anti-CD200 therapy |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982001011A1 (en) | 1980-09-24 | 1982-04-01 | Corp Cetus | Diagnostic method and probe |
| EP0084796B1 (de) | 1982-01-22 | 1990-05-02 | Cetus Corporation | Verfahren zur Charakterisierung von HLA und die darin benutzten cDNS-Testmittel |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5508178A (en) | 1989-01-19 | 1996-04-16 | Rose; Samuel | Nucleic acid amplification using single primer |
| US6291161B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for tapping the immunological repertiore |
| US6291160B1 (en) | 1989-05-16 | 2001-09-18 | Scripps Research Institute | Method for producing polymers having a preselected activity |
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-
2002
- 2002-09-19 DE DE60234369T patent/DE60234369D1/de not_active Expired - Lifetime
- 2002-09-19 US US10/251,085 patent/US7306906B2/en not_active Expired - Fee Related
- 2002-09-19 EP EP02775901A patent/EP1436404B1/de not_active Expired - Lifetime
- 2002-09-19 JP JP2003529974A patent/JP4439262B2/ja not_active Expired - Fee Related
- 2002-09-19 CA CA2460639A patent/CA2460639C/en not_active Expired - Fee Related
- 2002-09-19 DK DK02775901.8T patent/DK1436404T3/da active
- 2002-09-19 PT PT02775901T patent/PT1436404E/pt unknown
- 2002-09-19 ES ES02775901T patent/ES2336433T3/es not_active Expired - Lifetime
- 2002-09-19 AT AT02775901T patent/ATE448320T1/de active
- 2002-09-19 WO PCT/US2002/029889 patent/WO2003025202A2/en active Application Filing
- 2002-09-19 AU AU2002341752A patent/AU2002341752B2/en not_active Ceased
-
2009
- 2009-01-27 JP JP2009016031A patent/JP5107274B2/ja not_active Expired - Fee Related
-
2010
- 2010-01-18 CY CY20101100051T patent/CY1109828T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5107274B2 (ja) | 2012-12-26 |
| DK1436404T3 (da) | 2010-03-08 |
| PT1436404E (pt) | 2009-12-16 |
| EP1436404A2 (de) | 2004-07-14 |
| WO2003025202A2 (en) | 2003-03-27 |
| US7306906B2 (en) | 2007-12-11 |
| EP1436404B1 (de) | 2009-11-11 |
| JP2005503802A (ja) | 2005-02-10 |
| JP4439262B2 (ja) | 2010-03-24 |
| US20040072164A1 (en) | 2004-04-15 |
| WO2003025202A3 (en) | 2004-02-12 |
| CA2460639C (en) | 2013-07-16 |
| JP2009089716A (ja) | 2009-04-30 |
| AU2002341752B2 (en) | 2008-04-03 |
| ES2336433T3 (es) | 2010-04-13 |
| EP1436404A4 (de) | 2006-07-05 |
| CA2460639A1 (en) | 2003-03-27 |
| ATE448320T1 (de) | 2009-11-15 |
| CY1109828T1 (el) | 2014-09-10 |
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