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DE60233137D1 - Transporter mit beabstandeten arginin-teilchen - Google Patents

Transporter mit beabstandeten arginin-teilchen

Info

Publication number
DE60233137D1
DE60233137D1 DE60233137T DE60233137T DE60233137D1 DE 60233137 D1 DE60233137 D1 DE 60233137D1 DE 60233137 T DE60233137 T DE 60233137T DE 60233137 T DE60233137 T DE 60233137T DE 60233137 D1 DE60233137 D1 DE 60233137D1
Authority
DE
Germany
Prior art keywords
arginine
transport
transporter
filled
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60233137T
Other languages
English (en)
Inventor
Paul A Wender
Jonathan B Rothbard
Lee Wright
Erik L Kreider
Christopher L Vandeusen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CellGate Inc
Original Assignee
CellGate Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CellGate Inc filed Critical CellGate Inc
Application granted granted Critical
Publication of DE60233137D1 publication Critical patent/DE60233137D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
DE60233137T 2001-02-16 2002-02-14 Transporter mit beabstandeten arginin-teilchen Expired - Lifetime DE60233137D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26962701P 2001-02-16 2001-02-16
PCT/US2002/004491 WO2002065986A2 (en) 2001-02-16 2002-02-14 Transporters comprising spaced arginine moieties

Publications (1)

Publication Number Publication Date
DE60233137D1 true DE60233137D1 (de) 2009-09-10

Family

ID=23028023

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60233137T Expired - Lifetime DE60233137D1 (de) 2001-02-16 2002-02-14 Transporter mit beabstandeten arginin-teilchen

Country Status (9)

Country Link
US (3) US7585834B2 (de)
EP (1) EP1401473B1 (de)
JP (1) JP2005508832A (de)
AT (1) ATE437647T1 (de)
AU (1) AU2002306500C1 (de)
CA (1) CA2437983C (de)
DE (1) DE60233137D1 (de)
MX (1) MXPA03007358A (de)
WO (1) WO2002065986A2 (de)

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CA2437983A1 (en) 2002-08-29
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