Nothing Special   »   [go: up one dir, main page]

DE60215195D1 - Derivate morphinähnlicher opioidverbindungen - Google Patents

Derivate morphinähnlicher opioidverbindungen

Info

Publication number
DE60215195D1
DE60215195D1 DE60215195T DE60215195T DE60215195D1 DE 60215195 D1 DE60215195 D1 DE 60215195D1 DE 60215195 T DE60215195 T DE 60215195T DE 60215195 T DE60215195 T DE 60215195T DE 60215195 D1 DE60215195 D1 DE 60215195D1
Authority
DE
Germany
Prior art keywords
derivatives
compounds
morphinary
formula
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60215195T
Other languages
English (en)
Other versions
DE60215195T2 (de
Inventor
Roy Jackson
Rupika Subasinghe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monash University
Neuro Therapeutics Ltd
Original Assignee
Monash University
Neuro Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPR6938A external-priority patent/AUPR693801A0/en
Priority claimed from AUPR9640A external-priority patent/AUPR964001A0/en
Application filed by Monash University, Neuro Therapeutics Ltd filed Critical Monash University
Application granted granted Critical
Publication of DE60215195D1 publication Critical patent/DE60215195D1/de
Publication of DE60215195T2 publication Critical patent/DE60215195T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE60215195T 2001-08-10 2002-08-09 Derivate morphinähnlicher opioidverbindungen Expired - Fee Related DE60215195T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPR6938A AUPR693801A0 (en) 2001-08-10 2001-08-10 Therapeutic compounds
AUPR693801 2001-08-10
AUPR964001 2001-12-19
AUPR9640A AUPR964001A0 (en) 2001-12-19 2001-12-19 Therapeutic compounds
PCT/AU2002/001088 WO2003014122A1 (en) 2001-08-10 2002-08-09 Derivatives of morphine-like opioid compounds

Publications (2)

Publication Number Publication Date
DE60215195D1 true DE60215195D1 (de) 2006-11-16
DE60215195T2 DE60215195T2 (de) 2007-08-23

Family

ID=25646773

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60215195T Expired - Fee Related DE60215195T2 (de) 2001-08-10 2002-08-09 Derivate morphinähnlicher opioidverbindungen

Country Status (7)

Country Link
US (1) US7199129B2 (de)
EP (1) EP1423392B1 (de)
JP (1) JP2005500373A (de)
AT (1) ATE341552T1 (de)
AU (1) AU2002322169B2 (de)
DE (1) DE60215195T2 (de)
WO (1) WO2003014122A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040204862A1 (en) * 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
TWI541246B (zh) 2008-12-08 2016-07-11 歐陸斯迪公司 二氫羥戊甲嗎啡
WO2013043521A1 (en) 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Pyrazolopyridyl compounds as aldosterone synthase inhibitors
EP2757882B1 (de) 2011-09-22 2020-11-04 Merck Sharp & Dohme Corp. Imidazopyridylverbindungen als aldosteronsynthasehemmer
WO2013043520A1 (en) 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Triazolopyridyl compounds as aldosterone synthase inhibitors
JP6397407B2 (ja) 2012-07-19 2018-09-26 ドレクセル ユニバーシティ 細胞タンパク質ホメオスタシスを調節するためのシグマ受容体リガンド
GB201309654D0 (en) 2013-05-30 2013-07-17 Euro Celtique Sa Method
US9920836B2 (en) * 2013-10-18 2018-03-20 Kabushiki Kaisha Riken Piston ring for internal combustion engine
WO2019089902A1 (en) 2017-11-01 2019-05-09 Drexel University Compounds, compositions, and methods for treating diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341538A (en) * 1965-06-18 1967-09-12 Geigy Chem Corp Certain 2, 6-methano-3-benzazocines
EP1053238B1 (de) * 1998-01-29 2005-12-28 Monash University Therapeutische verbindungen
WO2002018348A2 (en) * 2000-08-31 2002-03-07 F. Hoffman-La Roche Ag Quinazoline derivatives as alpha-1 adrenergic antagonists

Also Published As

Publication number Publication date
EP1423392B1 (de) 2006-10-04
US20040242616A1 (en) 2004-12-02
DE60215195T2 (de) 2007-08-23
EP1423392A1 (de) 2004-06-02
US7199129B2 (en) 2007-04-03
EP1423392A4 (de) 2004-11-17
AU2002322169B2 (en) 2008-10-30
JP2005500373A (ja) 2005-01-06
ATE341552T1 (de) 2006-10-15
WO2003014122A1 (en) 2003-02-20

Similar Documents

Publication Publication Date Title
WO2003084938A3 (en) Pyrimidone derivatives useful for the treatment of inflammatin and immunological diseases
MY141559A (en) Triazole derivatives as tachykinin receptor antagonists
MXPA03011638A (es) Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
WO2002071827A3 (en) Retinoid x receptor modulators
WO2001064639A3 (en) Pde iv inhibiting amides, compositions and pharmaceutical use
MXPA02012033A (es) Derivados de 2-aminocarbonil-9h-purina.
GB0112348D0 (en) Compounds
DE60224172D1 (de) Formanilid-derivative als beta2-adrenorezeptor-agonisten
JO2372B1 (en) Source drugs of 4-phenylpyridine derivatives
MX2007005694A (es) Nuevos derivados de betulina, preparacion y uso de los mismos.
MY140057A (en) Novel heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine
ATE465738T1 (de) Neue kristalline formen der krebsbekämpfenden verbindung zd1839
MXPA05011411A (es) 1,4-diazepinas sustituidas y usos de las mismas.
AP1522A (en) Compounds having hypolipedemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them.
MXPA04002338A (es) Derivados de carbazol y su uso como antagonistas receptores del npy5.
MXPA03000161A (es) Compuestos novedosos los cuales tienen actividad antiinflamatoria, proceso para su preparacion y composiciones farmaceuticas que las contienen.
MY195576A (en) Novel Amino-Imidazopyridine Derivatives as Janus Kinase Inhibitors and Pharmaceutical use Thereof
DE60215195D1 (de) Derivate morphinähnlicher opioidverbindungen
MY128241A (en) Substituted tetracyclic pyrroloquinolone derivatives useful as phosphodiesterase inhibitors
MX2023012039A (es) Compuestos bicíclicos fusionados sustituidos como inhibidores de parp y uso de estos.
YU75101A (sh) Supstituisani biciklični heterocikli, postupak njihove izrade i njihova upotreba kao antigojaznih i hipoholesterolemijskih agenasa
MXPA04005426A (es) Derivados de pirazol de anillos fuisionados.
NO20060277L (no) Anvendelse av bisyklo [2.2.1] heptanderivater til fremstilling av nevrobeskyttende farmasoytiske sammensetninger
AU2003223340A8 (en) Certain pharmaceutically useful substituted aminoalkyl heterocycles
EP1179342A4 (de) Medizinische zusammensetzungen zur unmittelbaren freisetzung bei oraler anwendung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee