DE602007008872D1 - Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie - Google Patents
Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrieInfo
- Publication number
- DE602007008872D1 DE602007008872D1 DE602007008872T DE602007008872T DE602007008872D1 DE 602007008872 D1 DE602007008872 D1 DE 602007008872D1 DE 602007008872 T DE602007008872 T DE 602007008872T DE 602007008872 T DE602007008872 T DE 602007008872T DE 602007008872 D1 DE602007008872 D1 DE 602007008872D1
- Authority
- DE
- Germany
- Prior art keywords
- deglycosylation
- proteins
- molecular weight
- mass spectrometry
- microwave
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79733406P | 2006-05-02 | 2006-05-02 | |
PCT/US2007/067714 WO2007130875A2 (en) | 2006-05-02 | 2007-04-27 | Microwave assisted deglycosylation of proteins for molecular weight determination by mass spectrometry |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007008872D1 true DE602007008872D1 (de) | 2010-10-14 |
Family
ID=38648516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007008872T Active DE602007008872D1 (de) | 2006-05-02 | 2007-04-27 | Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie |
Country Status (8)
Country | Link |
---|---|
US (1) | US8163518B2 (de) |
EP (1) | EP2013356B1 (de) |
JP (1) | JP5219998B2 (de) |
AT (1) | ATE479770T1 (de) |
AU (1) | AU2007248253B2 (de) |
CA (1) | CA2650281C (de) |
DE (1) | DE602007008872D1 (de) |
WO (1) | WO2007130875A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010011002A1 (en) * | 2008-07-23 | 2010-01-28 | Industry-Academic Cooperation Foundation Gyeongsang National University | Method and system for diagnosing virus |
ES2802805T3 (es) * | 2013-03-15 | 2021-01-21 | Mayo Found Medical Education & Res | Identificación y seguimiento de inmunoglobulinas monoclonales por la masa molecular |
CA2944767C (en) | 2014-04-04 | 2022-07-12 | Mayo Foundation For Medical Education And Research | Isotyping immunoglobulins using accurate molecular mass |
WO2016018978A1 (en) | 2014-07-29 | 2016-02-04 | Mayo Foundation For Medical Education And Research | Quantifying monoclonal antibody therapeutics by lc-ms/ms |
WO2016174564A1 (en) * | 2015-04-30 | 2016-11-03 | Dh Technologies Development Pte. Ltd. | Identification of glycosylation forms |
WO2017053932A1 (en) | 2015-09-24 | 2017-03-30 | Mayo Foundation For Medical Education And Research | Identification of immunoglobulin free light chains by mass spectrometry |
US10955420B2 (en) | 2016-09-07 | 2021-03-23 | Mayo Foundation For Medical Education And Research | Identification and monitoring of cleaved immunoglobulins by molecular mass |
US11946937B2 (en) | 2017-09-13 | 2024-04-02 | Mayo Foundation For Medical Education And Research | Identification and monitoring of apoptosis inhibitor of macrophage |
EP3681907A4 (de) | 2017-09-13 | 2021-07-07 | Mayo Foundation for Medical Education and Research | Identifizierung und überwachung von immunglobulin-j-ketten |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5350686A (en) * | 1992-04-16 | 1994-09-27 | Pioneer Hi-Bred International, Inc. | Microwave acceleration of enzyme-catalyzed modification of macromolecules |
AUPN694895A0 (en) * | 1995-12-01 | 1996-01-04 | Macquarie Research Limited | Desalting and purification of oligosaccharides and their derivatives |
GB9821198D0 (en) * | 1998-09-30 | 1998-11-25 | Danisco | Enzyme |
US6960562B2 (en) * | 1999-04-23 | 2005-11-01 | Rhode Island Hospital, A Lifespan Partner | Tribonectin polypeptides and uses thereof |
US20030059432A1 (en) * | 2000-02-11 | 2003-03-27 | Dillon Davin C. | Lipophilin complexes for use in cancer diagnosis and therapy |
JP2004524810A (ja) * | 2000-09-18 | 2004-08-19 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Cripto変異体およびその使用 |
US6720165B2 (en) * | 2001-06-14 | 2004-04-13 | Zyomix, Inc. | Methods for making antibody fragments and compositions resulting therefrom |
EP1406089A1 (de) * | 2002-10-02 | 2004-04-07 | Taiwan Unison Biotechnology Co. Ltd. | Eine Methode zur selektiven Färbung wasserlöslicher Proteine unter Verwendung von Reaktivfarbstoffen |
US7112552B2 (en) * | 2002-10-18 | 2006-09-26 | Promega Corporation | Compositions for separating molecules |
US7662936B2 (en) * | 2004-04-07 | 2010-02-16 | Genentech, Inc. | Mass spectrometry of antibody conjugates |
-
2007
- 2007-04-27 AT AT07761533T patent/ATE479770T1/de not_active IP Right Cessation
- 2007-04-27 US US11/741,490 patent/US8163518B2/en active Active
- 2007-04-27 CA CA2650281A patent/CA2650281C/en active Active
- 2007-04-27 EP EP07761533A patent/EP2013356B1/de active Active
- 2007-04-27 DE DE602007008872T patent/DE602007008872D1/de active Active
- 2007-04-27 AU AU2007248253A patent/AU2007248253B2/en active Active
- 2007-04-27 WO PCT/US2007/067714 patent/WO2007130875A2/en active Application Filing
- 2007-04-27 JP JP2009509978A patent/JP5219998B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
US8163518B2 (en) | 2012-04-24 |
AU2007248253B2 (en) | 2010-12-23 |
US20070259398A1 (en) | 2007-11-08 |
WO2007130875A3 (en) | 2008-01-17 |
CA2650281C (en) | 2012-09-11 |
JP5219998B2 (ja) | 2013-06-26 |
WO2007130875A2 (en) | 2007-11-15 |
ATE479770T1 (de) | 2010-09-15 |
JP2009535646A (ja) | 2009-10-01 |
AU2007248253A1 (en) | 2007-11-15 |
CA2650281A1 (en) | 2007-11-15 |
EP2013356A2 (de) | 2009-01-14 |
EP2013356B1 (de) | 2010-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602007008872D1 (de) | Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie | |
CY1121562T1 (el) | Anti-fxi αντισωματα και μεθοδοι χρησης | |
WO2007098184A3 (en) | Methods and compositions for analyte detection | |
EA201100300A1 (ru) | Композиции и способы, предназначенные для направленного воздействия антител на белок c5 системы комплемента | |
CY1113199T1 (el) | Σταθεροποιημενες συνθεσεις γλυκοσερεμπροσιδασης | |
WO2010132453A3 (en) | Methods and compositions for analyte detection | |
EA200802005A1 (ru) | Стабилизированная связывающая молекула на основе стабилизированной молекулы scfv (варианты) и варианты получения и использования вышеназванных стабилизированных молекул | |
CL2008003784A1 (es) | Anticuerpo humanizado anti proteina e2 del virus de la hepatitis c o un fragmento de union; acido nucleico que lo codifica; vector y celula huesped que comprenden dicho acido nucleico; metodo para producir el anticuerpo; composicion farmaceutica que comprende el anticuerpo | |
WO2011047087A3 (en) | Protein detection via nanoreporters | |
CY1119127T1 (el) | Επιτοποι σκληροστινης | |
EP1994142A4 (de) | Verfahren und zusammensetzungen zur schnellen isolierung kleiner rna-moleküle | |
CY1117423T1 (el) | Παραγοντες που επηρεαζουν αποπτωση για τη θεραπεια καρκινου και ανοσων και αυτοανοσων ασθενειων | |
MX2018005512A (es) | Agentes de union de esclerostina. | |
EA201171494A1 (ru) | Миметики белка smac | |
WO2008140493A3 (en) | Anti-egfr family antibodies, bispecific anti-egfr family antibodies and methods of use thereof | |
WO2010045318A3 (en) | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type | |
DE602004025996D1 (de) | Immortalisierte Entezelllinien zur Viruserzeugung | |
EA200801531A1 (ru) | Способы регулирования содержания маннозы в рекомбинантных белках | |
EA201270553A1 (ru) | Ингибиторы тирозинкиназы брутона | |
BRPI0919377A2 (pt) | anticorpo isolado ou um fragmento ligante de antígeno do memso, ácido nucleico isolado, vetor, célula hospedeira, composição farmacêutica, método de produzir o referido anticorpo ou fragmento, uso dos mesmos, e composição compreendendo o referido anticorpo ou fragmento | |
EA200970210A1 (ru) | Prlr-специфическое антитело и его применения | |
EA200901313A1 (ru) | Ингибиторы тирозинкиназы брутона | |
WO2006101387A3 (en) | Method for interfering with blood coagulation by modulating cross-beta structures fibril formation | |
DE602005027258D1 (de) | Humane monoklonale antikörper gegen hendra- und nipah-viren | |
PH12015502849B1 (en) | Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers |