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DE602007008872D1 - Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie - Google Patents

Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie

Info

Publication number
DE602007008872D1
DE602007008872D1 DE602007008872T DE602007008872T DE602007008872D1 DE 602007008872 D1 DE602007008872 D1 DE 602007008872D1 DE 602007008872 T DE602007008872 T DE 602007008872T DE 602007008872 T DE602007008872 T DE 602007008872T DE 602007008872 D1 DE602007008872 D1 DE 602007008872D1
Authority
DE
Germany
Prior art keywords
deglycosylation
proteins
molecular weight
mass spectrometry
microwave
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007008872T
Other languages
English (en)
Inventor
David P Arnott
Jennie Lill
Wendy N Sandoval
Richard L Vandlen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE602007008872D1 publication Critical patent/DE602007008872D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE602007008872T 2006-05-02 2007-04-27 Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie Active DE602007008872D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79733406P 2006-05-02 2006-05-02
PCT/US2007/067714 WO2007130875A2 (en) 2006-05-02 2007-04-27 Microwave assisted deglycosylation of proteins for molecular weight determination by mass spectrometry

Publications (1)

Publication Number Publication Date
DE602007008872D1 true DE602007008872D1 (de) 2010-10-14

Family

ID=38648516

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007008872T Active DE602007008872D1 (de) 2006-05-02 2007-04-27 Mikrowellengestützte deglycosylierung von proteinen zur molekulargewichtsbestimmung durch massenspektrometrie

Country Status (8)

Country Link
US (1) US8163518B2 (de)
EP (1) EP2013356B1 (de)
JP (1) JP5219998B2 (de)
AT (1) ATE479770T1 (de)
AU (1) AU2007248253B2 (de)
CA (1) CA2650281C (de)
DE (1) DE602007008872D1 (de)
WO (1) WO2007130875A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010011002A1 (en) * 2008-07-23 2010-01-28 Industry-Academic Cooperation Foundation Gyeongsang National University Method and system for diagnosing virus
ES2802805T3 (es) * 2013-03-15 2021-01-21 Mayo Found Medical Education & Res Identificación y seguimiento de inmunoglobulinas monoclonales por la masa molecular
CA2944767C (en) 2014-04-04 2022-07-12 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
WO2016018978A1 (en) 2014-07-29 2016-02-04 Mayo Foundation For Medical Education And Research Quantifying monoclonal antibody therapeutics by lc-ms/ms
WO2016174564A1 (en) * 2015-04-30 2016-11-03 Dh Technologies Development Pte. Ltd. Identification of glycosylation forms
WO2017053932A1 (en) 2015-09-24 2017-03-30 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
US10955420B2 (en) 2016-09-07 2021-03-23 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
US11946937B2 (en) 2017-09-13 2024-04-02 Mayo Foundation For Medical Education And Research Identification and monitoring of apoptosis inhibitor of macrophage
EP3681907A4 (de) 2017-09-13 2021-07-07 Mayo Foundation for Medical Education and Research Identifizierung und überwachung von immunglobulin-j-ketten

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350686A (en) * 1992-04-16 1994-09-27 Pioneer Hi-Bred International, Inc. Microwave acceleration of enzyme-catalyzed modification of macromolecules
AUPN694895A0 (en) * 1995-12-01 1996-01-04 Macquarie Research Limited Desalting and purification of oligosaccharides and their derivatives
GB9821198D0 (en) * 1998-09-30 1998-11-25 Danisco Enzyme
US6960562B2 (en) * 1999-04-23 2005-11-01 Rhode Island Hospital, A Lifespan Partner Tribonectin polypeptides and uses thereof
US20030059432A1 (en) * 2000-02-11 2003-03-27 Dillon Davin C. Lipophilin complexes for use in cancer diagnosis and therapy
JP2004524810A (ja) * 2000-09-18 2004-08-19 バイオジェン・アイデック・エムエイ・インコーポレイテッド Cripto変異体およびその使用
US6720165B2 (en) * 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
EP1406089A1 (de) * 2002-10-02 2004-04-07 Taiwan Unison Biotechnology Co. Ltd. Eine Methode zur selektiven Färbung wasserlöslicher Proteine unter Verwendung von Reaktivfarbstoffen
US7112552B2 (en) * 2002-10-18 2006-09-26 Promega Corporation Compositions for separating molecules
US7662936B2 (en) * 2004-04-07 2010-02-16 Genentech, Inc. Mass spectrometry of antibody conjugates

Also Published As

Publication number Publication date
US8163518B2 (en) 2012-04-24
AU2007248253B2 (en) 2010-12-23
US20070259398A1 (en) 2007-11-08
WO2007130875A3 (en) 2008-01-17
CA2650281C (en) 2012-09-11
JP5219998B2 (ja) 2013-06-26
WO2007130875A2 (en) 2007-11-15
ATE479770T1 (de) 2010-09-15
JP2009535646A (ja) 2009-10-01
AU2007248253A1 (en) 2007-11-15
CA2650281A1 (en) 2007-11-15
EP2013356A2 (de) 2009-01-14
EP2013356B1 (de) 2010-09-01

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