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DE60042196D1 - In der e1b-region deletierte, adenovirale shuttle-vektoren - Google Patents

In der e1b-region deletierte, adenovirale shuttle-vektoren

Info

Publication number
DE60042196D1
DE60042196D1 DE60042196T DE60042196T DE60042196D1 DE 60042196 D1 DE60042196 D1 DE 60042196D1 DE 60042196 T DE60042196 T DE 60042196T DE 60042196 T DE60042196 T DE 60042196T DE 60042196 D1 DE60042196 D1 DE 60042196D1
Authority
DE
Germany
Prior art keywords
region
deleted
shuttle vectors
gene
adenoviral shuttle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60042196T
Other languages
English (en)
Inventor
Terry Hermiston
Julie Nye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Onyx Pharmaceuticals Inc
Original Assignee
Onyx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onyx Pharmaceuticals Inc filed Critical Onyx Pharmaceuticals Inc
Application granted granted Critical
Publication of DE60042196D1 publication Critical patent/DE60042196D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Image Generation (AREA)
  • Image Processing (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60042196T 1999-01-28 2000-01-26 In der e1b-region deletierte, adenovirale shuttle-vektoren Expired - Lifetime DE60042196D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11781499P 1999-01-28 1999-01-28
PCT/US2000/002029 WO2000044922A1 (en) 1999-01-28 2000-01-26 E1b-deleted adenoviral shuttle vectors

Publications (1)

Publication Number Publication Date
DE60042196D1 true DE60042196D1 (de) 2009-06-25

Family

ID=22374975

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60042196T Expired - Lifetime DE60042196D1 (de) 1999-01-28 2000-01-26 In der e1b-region deletierte, adenovirale shuttle-vektoren

Country Status (10)

Country Link
EP (1) EP1135514B1 (de)
AT (1) ATE431421T1 (de)
AU (1) AU772544B2 (de)
CA (1) CA2360355A1 (de)
CY (1) CY1109288T1 (de)
DE (1) DE60042196D1 (de)
DK (1) DK1135514T3 (de)
ES (1) ES2325303T3 (de)
PT (1) PT1135514E (de)
WO (1) WO2000044922A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030086903A1 (en) 2001-11-02 2003-05-08 Genvec, Inc. Therapeutic regimen for treating cancer
US20030219410A1 (en) * 2002-02-01 2003-11-27 Transgene S.A. Adenoviral vectors for modulating the cellular activities associated to PODs
EP3029144B1 (de) 2009-03-02 2019-07-10 The Regents of The University of California Tumorselektive adenovirus e1a und e1b mutanten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670488A (en) * 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
US5801029A (en) * 1993-02-16 1998-09-01 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
US5981275A (en) * 1997-04-14 1999-11-09 Genzyme Corporation Transgene expression system for increased persistence

Also Published As

Publication number Publication date
PT1135514E (pt) 2009-07-20
DK1135514T3 (da) 2009-09-07
CA2360355A1 (en) 2000-08-03
ATE431421T1 (de) 2009-05-15
CY1109288T1 (el) 2014-07-02
EP1135514A1 (de) 2001-09-26
AU772544B2 (en) 2004-04-29
AU2861300A (en) 2000-08-18
EP1135514B1 (de) 2009-05-13
ES2325303T3 (es) 2009-09-01
WO2000044922A1 (en) 2000-08-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition