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DE60034110D1 - Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien - Google Patents

Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien

Info

Publication number
DE60034110D1
DE60034110D1 DE60034110T DE60034110T DE60034110D1 DE 60034110 D1 DE60034110 D1 DE 60034110D1 DE 60034110 T DE60034110 T DE 60034110T DE 60034110 T DE60034110 T DE 60034110T DE 60034110 D1 DE60034110 D1 DE 60034110D1
Authority
DE
Germany
Prior art keywords
aminopyridine
treatment
peripheral neuropathies
nervous system
provides methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034110T
Other languages
English (en)
Other versions
DE60034110T2 (de
Inventor
Jay M Meythaler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
Original Assignee
UAB Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation filed Critical UAB Research Foundation
Application granted granted Critical
Publication of DE60034110D1 publication Critical patent/DE60034110D1/de
Publication of DE60034110T2 publication Critical patent/DE60034110T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE60034110T 1999-02-09 2000-02-09 Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien Expired - Lifetime DE60034110T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11927399P 1999-02-09 1999-02-09
US119273P 1999-02-09
PCT/US2000/003396 WO2000047210A1 (en) 1999-02-09 2000-02-09 Use of 4-amino pyridine for treatment of peripheral neuropathies

Publications (2)

Publication Number Publication Date
DE60034110D1 true DE60034110D1 (de) 2007-05-10
DE60034110T2 DE60034110T2 (de) 2007-12-06

Family

ID=22383494

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034110T Expired - Lifetime DE60034110T2 (de) 1999-02-09 2000-02-09 Verwendung von 4-aminopyridin zur behandlung von peripheren neuropathien

Country Status (10)

Country Link
US (1) US6503931B1 (de)
EP (1) EP1152760B1 (de)
JP (1) JP2002536413A (de)
AT (1) ATE357914T1 (de)
AU (1) AU3360000A (de)
CA (1) CA2360326C (de)
DE (1) DE60034110T2 (de)
DK (1) DK1152760T3 (de)
ES (1) ES2284485T3 (de)
WO (1) WO2000047210A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2820423B1 (fr) * 2001-02-05 2005-12-02 Assist Publ Hopitaux De Paris Tartrate et phosphate de 3,4-diaminopyridine, compositions pharmaceutiques et utilisations
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
WO2013003708A1 (en) 2011-06-30 2013-01-03 Biomarin Pharmaceuticals, Inc. Methods of administering 3,4-diaminopyridine
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法
US9993429B2 (en) 2013-03-15 2018-06-12 University Of Rochester Composition and methods for the treatment of peripheral nerve injury
MA35698B1 (fr) * 2013-05-16 2014-12-01 Univ Mohammed V Souissi Nouvelle composition du 3,4-diaminopyridin pour le traitement de la fatigabilité musculaire associée à des troubles neurovégétatifs.
WO2024011220A1 (en) 2022-07-08 2024-01-11 University Of Rochester Potassium channel blockers or derivatives thereof for preventing, alleviating, and/or treating tissue dysfunction caused by toxic insults

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221683A (en) * 1984-03-19 1993-06-22 The Rockefeller University Diaminopyridine compounds and methods of use
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
CA2085785C (en) * 1992-12-18 2005-03-15 Robert R. Hansebout The use of 4-aminopyridine in the treatment of a neurological condition

Also Published As

Publication number Publication date
US6503931B1 (en) 2003-01-07
CA2360326A1 (en) 2000-08-17
DK1152760T3 (da) 2007-07-30
AU3360000A (en) 2000-08-29
ATE357914T1 (de) 2007-04-15
ES2284485T3 (es) 2007-11-16
EP1152760B1 (de) 2007-03-28
JP2002536413A (ja) 2002-10-29
CA2360326C (en) 2011-04-05
EP1152760A4 (de) 2005-03-23
DE60034110T2 (de) 2007-12-06
EP1152760A1 (de) 2001-11-14
WO2000047210A1 (en) 2000-08-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition