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DE3473268D1 - 5-fluorouracilnitroxylderivatives - Google Patents

5-fluorouracilnitroxylderivatives

Info

Publication number
DE3473268D1
DE3473268D1 DE8484901562T DE3473268T DE3473268D1 DE 3473268 D1 DE3473268 D1 DE 3473268D1 DE 8484901562 T DE8484901562 T DE 8484901562T DE 3473268 T DE3473268 T DE 3473268T DE 3473268 D1 DE3473268 D1 DE 3473268D1
Authority
DE
Germany
Prior art keywords
fluorouracilnitroxyl
derivatives
fluorouracilnitroxyl derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484901562T
Other languages
English (en)
Inventor
Nikolai Markovich Emanuel
Albina Nikolaevna Rozenberg
Valery Alexandrovich Golubev
Gennady Nikolaevich Bogdanov
Ljubov Sergeevna Vasilieva
Nina Petrovna Konovalova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST KHIM FIZ AN SSSR
Original Assignee
INST KHIM FIZ AN SSSR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST KHIM FIZ AN SSSR filed Critical INST KHIM FIZ AN SSSR
Application granted granted Critical
Publication of DE3473268D1 publication Critical patent/DE3473268D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8484901562T 1983-03-11 1984-03-07 5-fluorouracilnitroxylderivatives Expired DE3473268D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SU833557801A SU1235864A1 (ru) 1983-03-11 1983-03-11 Нитроксильные производные 5-фторурацила,обладающие противоопухолевой активностью
PCT/SU1984/000013 WO1984003510A1 (en) 1983-03-11 1984-03-07 Nitroxyl derivatives of 5-fluorineuracil having antitumoral activity

Publications (1)

Publication Number Publication Date
DE3473268D1 true DE3473268D1 (de) 1988-09-15

Family

ID=21051504

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484901562T Expired DE3473268D1 (de) 1983-03-11 1984-03-07 5-fluorouracilnitroxylderivatives

Country Status (6)

Country Link
US (1) US4558127A (de)
EP (1) EP0139023B1 (de)
JP (1) JPS60500869A (de)
DE (1) DE3473268D1 (de)
SU (1) SU1235864A1 (de)
WO (1) WO1984003510A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7549977B2 (en) * 2002-12-20 2009-06-23 Medrad, Inc. Front load pressure jacket system with syringe holder and light illumination

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168391A (en) * 1968-01-08 1969-10-22 Inst Organocheskogo Sinteza An Substituted Uracils
SU721439A1 (ru) * 1973-03-06 1980-03-15 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср Способ получени -(2-фуранидил)- 5-замещенных урацилов
JPS5324952B2 (de) * 1973-11-28 1978-07-24
AT344190B (de) * 1976-05-28 1978-07-10 Hoffmann La Roche Verfahren zur herstellung von 1- (2-tetrahydrofuryl)-5-fluoruracil
JPS6052708B2 (ja) * 1976-12-24 1985-11-20 エーザイ株式会社 ５−フルオロウラシル系化合物およびそれを含有する抗腫瘍剤
JPS6011706B2 (ja) * 1977-01-10 1985-03-27 小野薬品工業株式会社 ５−フルオロウラシル誘導体化合物
ES8205399A1 (es) * 1980-01-07 1982-06-01 Nyegaard & Co As Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
JPS591498A (ja) * 1982-06-24 1984-01-06 Chisso Corp １，２：５，６−ジ−０−イソプロピリデン−３−０〔３−（５−フルオロウラシル−１−イル）プロピオノイル〕α−Ｄ−グルコフラノ−ス

Also Published As

Publication number Publication date
EP0139023B1 (de) 1988-08-10
EP0139023A1 (de) 1985-05-02
EP0139023A4 (de) 1985-07-30
WO1984003510A1 (en) 1984-09-13
US4558127A (en) 1985-12-10
JPS60500869A (ja) 1985-06-06
SU1235864A1 (ru) 1986-06-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee