DE202005017053U1 - Nutrient preparation, useful e.g. for nutritive supplement with increase joint stress and joint disease, comprises glucosamine, chondroitin; collagen hydrolysate; and optionally vitamin C - Google Patents

Abstract

Nutrient preparation (I) comprises: (a) glucosamine and/or its enantiomers, diastereomers, derivatives and/or physiologically compatible salts (600 mg - 2 g); (b) chondroitin and/or its enantiomers, diastereomers, derivatives and/or physiologically compatible salts (400 mg - 1.5 g); (c) collagen hydrolysate (5-15 g); and optionally (d) vitamin C (100-500 mg), related to daily dose of (I). Nutrient preparation (I) (preferably suitable for the nutritive supplement with increase joint stress and joint disease) comprises: (a) glucosamine and/or its enantiomers, diastereomers, derivatives and/or physiologically compatible salts (600 mg - 2 g); (b) chondroitin and/or its enantiomers, diastereomers, derivatives and/or physiologically compatible salts (400 mg - 1.5 g); (c) collagen hydrolysate (5-15 g); and optionally (d) vitamin C (100-500 mg), related to daily dose of (I). ACTIVITY : Antirheumatic; Antiinflammatory; Osteopathic; Antiarthritic; Analgesic. MECHANISM OF ACTION : None given.

Description

The The present invention relates to a nutrient preparation, especially for nutritive complement at an elevated Joint stress or joint disease is suitable.

In the joints, as in knees, elbows or fingers, serve the hard but at the same time elastic cartilage, which is the bone ends surrounds, protecting the joints while ensuring the necessary Mobility, softness and joint lubrication.

Progressive end Age and associated long-term wear as well Abrasion of the articular cartilage, but also the joints stressful sports, Deformity, physical Stress, poor posture, nutritional error or overweight can already cause joint problems or arthrosis in adolescence.

One painful wear of the Articular cartilage and degenerative joint diseases are in the population widely used and one of the most common Reasons for Incapacity for work. Not only in everyday life can a nutritive undersupply of articular cartilage cause that the articular cartilage only functions inadequately or not exercise more can. As a result, the cartilage in the joint capsules becomes brittle and shrinks. This erosion of the cartilage layer can cause joint diseases like Osteoarthritis, inflammation of joints, swelling, stiffness, restricted mobility, arthritis, thickening or cause deformation, the common accompanied by pain.

in the The state of the art is medicinal, surgical and physical Therapies for the treatment of diseases of the joints, in particular known from the rheumatic circle. Also means to supplement, to Treatment of osteoarthritis and rheumatoid arthritis affecting the articular cartilage regenerate are known.

One Disadvantage of many products is that this is a holistic Supply of cartilage and bone with basic building materials and trace elements but without taking into account the specific needs of the cartilage to wear.

It There is therefore a need for an instrument specifically designed to strengthen the Cartilage was developed. About that There is also a need for an agent that as such does not harm human health Causes side effects and thus harmless to the precautionary support of articular cartilage.

It is therefore the object of the present invention, a means for disposal to provide, at least one of the aforementioned disadvantages of the prior art technology overcomes. In particular, it is the object of the present invention, a Funds available to provide a comprehensive supply of articular cartilage.

• a. Glucosamin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 600 mg bis ≤ 2 g;
• b. Chondroitin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 400 mg bis ≤ 1,5 g;
• c. Kollagenhydrolysat im Bereich von ≥ 5 g bis ≤ 15 g;
• d. gegebenenfalls Vitamin C im Bereich von ≥ 100 mg bis ≤ 500 mg.

This object is achieved by a nutrient preparation, in particular suitable for nutritive supplementation in the case of increased joint stress and joint diseases, wherein the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active constituents the following substances:

• a. Glucosamine and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 600 mg to ≤ 2 g;
• b. Chondroitin and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 400 mg to ≤ 1.5 g;
• c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g;
• d. optionally vitamin C in the range of ≥ 100 mg to ≤ 500 mg.

Surprised has been shown that by a supplementary diet with the nutrient preparation according to the invention the general joint function can be positively influenced.

Surprised could be found in particular that by the combination according to the invention the contained substances of cartilage degradation or cartilage abrasion delayed or can be reduced, as well as the regeneration of cartilage positive can be influenced. Also a construction or a renewal of the Cartilage can be made possible. A particular advantage of the preparation according to the invention can thereby be realized be that particular relief of joint disease and / or joint wear associated Pain and its intensity can be achieved. In particular, it is advantageous that the function positively affects the joints and preserves the function can be. Overall, by administering the nutrient preparation according to the invention a significant improvement in mobility and pain the affected person.

These advantageous properties of the erfindungemäßen nutrient preparation emerge from the special selection and dosage of the individual substances.

The term "daily dose" in the context of this invention, the amount of the preparation ver which is supplied per day, wherein the amount of substance that should be supplied per day can be within the specified ranges of the respective substances. The term daily dose can be understood as a daily intake.

Under The term "substance" are within the meaning of this invention to understand the substances that the nutrient preparation has, in particular selected from the group comprising glucosamine, preferably glucosamine sulphate, Chondroitin, preferably chondroitin sulfate, vitamin C and / or Collagen hydrolyzate.

• a. Glucosamin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 800 mg bis ≤ 1,5 g, bevorzugt 1,2 g Glucosamin;
• b. Chondroitin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 600 mg bis ≤ 1,2 g, bevorzugt 800 mg Chondroitin;
• c. Kollagenhydrolysat im Bereich von ≥ 9 g bis ≤ 12 g, bevorzugt 10 g Kollagenhydrolysat; und/oder
• d. gegebenenfalls Vitamin C im Bereich von ≥ 120 mg bis ≤ 230 mg, bevorzugt 200 mg Vitamin C.

In advantageous embodiments, the nutrient preparation, based on a daily dose of the preparation, comprises as active ingredients the following substances:

• a. Glucosamine and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g of glucosamine;
• b. Chondroitin and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg of chondroitin;
• c. Collagen hydrolyzate in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or
• d. optionally vitamin C in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C.

In preferred embodiments has the nutrient preparation glucosamine and / or chondroitin in the form of compounds selected from the group comprising their enantiomers, diastereomers, derivatives such as amides or esters, physiologically acceptable salts and / or mixtures of it. Preferably contains the nutritional supplement glucosamine and / or chondroitin in the form of physiologically acceptable Salt.

advantageously, The administration of glucosamine can help reduce the pain in the affected joint.

In preferred embodiments glucosamine is in the form of compounds selected from the group comprising Glucosamine sulfate, glucosamine hydrochloride and / or N-acetyl-glucosamine ago. In particularly preferred embodiments are the physiologically tolerable Salts of glucosamine selected from the group comprising glucosamine sulfate and / or glucosamine hydrochloride. Also usable are sodium and / or potassium salts of Glucosamine. Very particularly preferably usable is glucosamine sulfate.

It It is believed that the use of glucosamine sulfate to a across from other salts may lead to improved bio-availability of glucosamine and thus to a reduction in the amount to be administered Glucosamine can contribute.

In furthermore preferred embodiments are among the physiologically acceptable salts of chondroitin Salts selected from the group comprising chondroitin sulphates and / or chondroitin hydrochloride usable. Very particular preference is given to using chondroitin sulfates, preferably selected from the group comprising chondroitin 4-sulfate and / or chondroitin 6-sulfate.

One particular advantage of chondroitin results from the fact that chondroitin a positive impact on inflammation and swelling as well the resulting stiffness and pain in the joints exercise can.

When Particularly advantageous in the context of the invention has the use the sulfates of chondroitin and glucosamine proved. In preferred embodiments contains the nutritional supplement glucosamine sulfate and chondroitin sulfate.

Preferably is the invention to be used Glucosamine D-glucosamine. Very particularly advantageous used D-glucosamine, D-glucosamine sulfate, D-glucosamine hydrochloride, N-acetyl-D-glucosamine or mixtures thereof.

• a. Glucosaminsulfat im Bereich von ≥ 600 mg bis ≤ 2 g, vorzugsweise im Bereich von ≥ 800 mg bis ≤ 1,5 g, bevorzugt 1,2 g Glucosaminsulfat;
• b. Chondroitinsulfat im Bereich von ≥ 400 mg bis ≤ 1,5 g, vorzugsweise im Bereich von ≥ 600 mg bis ≤ 1,2 g, bevorzugt 800 mg Chondroitinsulfat;
• c. Kollagenhydrolysat im Bereich von ≥ 5 g bis ≤ 15 g, vorzugsweise im Bereich von ≥ 9 g bis ≤ 12 g, bevorzugt 10 g Kollagenhydrolysat; und/oder
• d. gegebenenfalls Vitamin C im Bereich von ≥ 100 mg bis ≤ 500 mg, vorzugsweise im Bereich von ≥ 120 mg bis ≤ 230 mg, bevorzugt 200 mg Vitamin C.

In particularly preferred embodiments, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises the substances as active constituents:

• a. Glucosamine sulfate in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g of glucosamine sulfate;
• b. Chondroitin sulfate in the range of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg of chondroitin sulfate;
• c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or
• d. optionally vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C.

• a. Glucosamin-Hydrochlorid im Bereich von ≥ 600 mg bis ≤ 2 g, vorzugsweise im Bereich von ≥ 800 mg bis ≤ 1,5 g, bevorzugt 1,2 g Glucosaminsulfat;
• b. Chondroitin-Hydrochlorid im Bereich von ≥ 400 mg bis ≤ 1,5 g, vorzugsweise im Bereich von ≥ 600 mg bis ≤ 1,2 g, bevorzugt 800 mg Chondroitinsulfat;
• c. Kollagenhydrolysat im Bereich von ≥ 5 g bis ≤ 15 g, vorzugsweise im Bereich von ≥ 9 g bis ≤ 12 g, bevorzugt 10 g Kollagenhydrolysat; und/oder
• d. gegebenenfalls Vitamin C im Bereich von ≥ 100 mg bis ≤ 500 mg, vorzugsweise im Bereich von ≥ 120 mg bis ≤ 230 mg, bevorzugt 200 mg Vitamin C.

In further preferred embodiments, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. Glucosamine hydrochloride in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g of glucosamine sulfate;
• b. Chondroitin hydrochloride in the range of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg of chondroitin sulfate;
• c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or
• d. optionally vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C.

• a. N-Acetyl-Glucosamin im Bereich von ≥ 600 mg bis ≤ 2 g, vorzugsweise im Bereich von ≥ 800 mg bis ≤ 1,5 g, bevorzugt 1,2 g Glucosaminsulfat;
• b. Chondroitinsulfat im Bereich von ≥ 400 mg bis ≤ 1,5 g, vorzugsweise im Bereich von ≥ 600 mg bis ≤ 1,2 g, bevorzugt 800 mg Chondroitinsulfat;
• c. Kollagenhydrolysat im Bereich von ≥ 5 g bis ≤ 15 g, vorzugsweise im Bereich von ≥ 9 g bis ≤ 12 g, bevorzugt 10 g Kollagenhydrolysat; und/oder
• d. gegebenenfalls Vitamin C im Bereich von ≥ 100 mg bis ≤ 500 mg, vorzugsweise im Bereich von ≥ 120 mg bis ≤ 230 mg, bevorzugt 200 mg Vitamin C.

In even further preferred embodiments, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. N-acetyl-glucosamine in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g of glucosamine sulfate;
• b. Chondroitin sulfate in the range of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg of chondroitin sulfate;
• c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or
• d. optionally vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C.

The Administration of the nutrient preparation according to the invention can especially in people with arthrosis or people whose joints be particularly stressed, for example, by sports or obesity, Complaints such as joint inflammation, Thickening, pain and resulting immobility, Stiffening and movement restrictions significantly reduce. A regular administration of the nutrient preparation can lead to a significant improvement in joint disease.

The advantageous properties of the preparation according to the invention will be apparent from the optimized selection and tuning of each substance specifically for support of the cartilage structure as well as to support the joint functions were selected. Thus, for example, one due to nutritional deficits or high stress as if overweight or sports caused damage of the articular cartilage are positively influenced.

One Another advantage of the nutrient preparation according to the invention is through the administration of collagen hydrolyzate. So can an administration collagen hydrolyzate cause stabilization of the cartilage matrix.

In preferred embodiments contains that Nutrient preparation continues Vitamin C. Vitamin C can realize further advantages of the nutrient preparation, in particular Vitamin C can contribute to the strength of connective tissue and before arthrotic changes protect. In particular, it is conceivable that by adding vitamin C a synergistic effect and the nutrient preparation can have an effect on the articular cartilage and the mobility of the joints can. The nutrient preparation can especially with the addition of vitamin C a comprehensive care of the joints available and stabilize the entire function of the joints or improve.

• a. Glucosamin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 2 g bis ≤ 10 g, vorzugsweise im Bereich von ≥ 5 g bis ≤ 10 g, bevorzugt 7,5 g;
• b. Chondroitin und/oder dessen Enantiomere, Diastereomere, Derivate und/oder physiologisch verträgliche Salze im Bereich von ≥ 2 g bis ≤ 10 g, vorzugsweise im Bereich von ≥ 4 g bis ≤ 8 g, bevorzugt 5,0 g; und/oder
• c. Kollagenhydrolysat im Bereich von ≥ 20 g bis ≤ 80 g, vorzugsweise im Bereich von ≥ 40 g bis ≤ 80 g, bevorzugt 62,5 g.

Preferably, the nutrient preparation, based on 100 g of the nutrient preparation, comprises as active ingredients the following substances:

• a. Glucosamine and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 5 g to ≤ 10 g, preferably 7.5 g;
• b. Chondroitin and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 4 g to ≤ 8 g, preferably 5.0 g; and or
• c. Collagen hydrolyzate in the range of ≥ 20 g to ≤ 80 g, preferably in the range of ≥ 40 g to ≤ 80 g, preferably 62.5 g.

• a. Glucosaminsulfat im Bereich von ≥ 2 g bis ≤ 10 g, vorzugsweise im Bereich von ≥ 5 g bis ≤ 10 g, bevorzugt 7,5 g;
• b. Chondroitinsulfat im Bereich von ≥ 2 g bis ≤ 10 g, vorzugsweise im Bereich von ≥ 4 g bis ≤ 8 g, bevorzugt 5,0 g; und/oder
• c. Kollagenhydrolysat im Bereich von ≥ 20 g bis ≤ 80 g, vorzugsweise im Bereich von ≥ 40 g bis ≤ 80 g, bevorzugt 62,5 g.

The nutrient preparation, based on 100 g of the nutrient preparation, particularly preferably comprises the following substances as active constituents:

• a. Glucosamine sulfate in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 5 g to ≤ 10 g, preferably 7.5 g;
• b. Chondroitin sulfate in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 4 g to ≤ 8 g, preferably 5.0 g; and or
• c. Collagen hydrolyzate in the range of ≥ 20 g to ≤ 80 g, preferably in the range of ≥ 40 g to ≤ 80 g, preferably 62.5 g.

The nutrient preparation may be solid, liquid and / or gel. The preparation is preferably present in preparation forms selected from the group consisting of tablets, capsules, powders, granules, solutions, effervescent tablets and / or spray, particularly preferably in the form of tablets, capsules, effervescent tablets, powders, granules and / or solutions with the same or the same different composition. In particularly preferred embodiments, the nutrient preparation is in the form of 1 to 15 tablets, capsules, effervescent tablets, powders, granules and / or solutions of identical or different composition, preferably in the form of 5 to 12 tablets, 5 to 12 capsules and / or 3 to 5 effervescent tablets with the same or different composition. In very particularly preferred embodiments, the nutrient preparation is in the form of 1 to 5 administration units, for example bags, of granules, preferably 1 to 3 granules, especially before 1 to 2 granules with the same or different composition before. In particularly preferred embodiments, the nutrient preparation is in granular form.

One Another beneficial effect of the preparation may be the possibility result, the substances contained in separate preparation forms, preferably administered separately in several doses. advantageously, can the nutrient preparation in Form of at least one preparation form, preferred in the form of two separate preparation forms, preferably in Form least three separate preparation forms are present, wherein drug forms same or different compositions of substances and / or Can have substance weight levels.

Preferably includes a preparation form the substances and / or the substance weight in the amount of a Daily dose. However, it can also be provided that the daily dose can be distributed over several identical or different preparation forms, the preparation forms also identical or different substances and / or substance weight contents can have.

Farther may be provided that the daily dose to one or more Distributed single doses can be administered, for example, a Daily dose to be divided into two single doses.

• a. 600 mg Glucosaminsulfat;
• b. 400 mg Chondroitinsulfat;
• c. 5 g Kollagenhydrolysat.

In a preferred embodiment, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. 600 mg glucosamine sulfate;
• b. 400 mg chondroitin sulfate;
• c. 5 g collagen hydrolyzate.

• a. 600 mg Glucosaminsulfat;
• b. 400 mg Chondroitinsulfat;
• c. 5 g Kollagenhydrolysat.

In a preferred embodiment, the nutrient preparation, based on a single dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. 600 mg glucosamine sulfate;
• b. 400 mg chondroitin sulfate;
• c. 5 g collagen hydrolyzate.

• a. 1,2 g Glucosaminsulfat;
• b. 800 mg Chondroitinsulfat;
• c. 10 g Kollagenhydrolysat.

In a further preferred embodiment, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active constituents the following substances:

• a. 1.2 g of glucosamine sulfate;
• b. 800 mg chondroitin sulfate;
• c. 10 g collagen hydrolyzate.

• a. 1,2 g Glucosaminsulfat,
• b. 800 mg Chondroitinsulfat,
• c. 10 g Kollagenhydrolysat.

In a further preferred embodiment, the nutrient preparation, based on a single dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. 1.2 g glucosamine sulfate,
• b. 800 mg chondroitin sulfate,
• c. 10 g collagen hydrolyzate.

• a. 1,2 g Glucosaminsulfat,
• b. 800 mg Chondroitinsulfat,
• c. 10 g Kollagenhydrolysat,
• d. 200 mg Vitamin C.

In a still further preferred embodiment, the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. 1.2 g glucosamine sulfate,
• b. 800 mg chondroitin sulfate,
• c. 10 g collagen hydrolyzate,
• d. 200 mg of vitamin C.

• a. 1,2 g Glucosaminsulfat,
• b. 800 mg Chondroitinsulfat,
• c. 10 g Kollagenhydrolysat,
• d. 200 mg Vitamin C.

In a still further preferred embodiment, the nutrient preparation, based on a single dose of the nutrient preparation, comprises as active ingredients the following substances:

• a. 1.2 g glucosamine sulfate,
• b. 800 mg chondroitin sulfate,
• c. 10 g collagen hydrolyzate,
• d. 200 mg of vitamin C.

Under a "single dose" is in the sense of this Sign a delivery unit of the preparation understood. A single dose corresponds, for example, to a bag of granules, a tablet, a capsule or a single unit of administration of another preparation form like powder or solution.

The Nutrient preparation can a dietary supplement, dietetic Food, and / or food in particular a so-called "novel food" be. Under the Term "novel food" are in the sense of this Invention to understand all foods and food ingredients the not before 15.05.1997 to a significant extent in the European Community for the human consumption, such as food and food ingredients with new or specifically modified primary molecular structure, Food and food ingredients derived from microorganisms, fungi or algae are or have been isolated from these foods and food ingredients consisting of plants or of plants have been isolated and food ingredients isolated from animals, except Food or food ingredients with conventional Propagation or breeding methods were obtained and experience has shown that they are harmless Food can apply and / or food and food ingredients, in their manufacture a not usual Method has been applied and in which this method a significant change their composition or the structure of the food or food ingredients what has affected their nutritional value, their metabolism or on the amount of unwanted Substances in the food.

Prefers The nutrient preparation can be considered nutritive complement to accompany or support Administration can be used.

Especially can the nutrient preparation for nutritive supplement, accompanying or supporting Treatment and / or prophylaxis in persons with joint diseases like osteoarthritis, at an elevated level Stress on the joints, for example due to sports or obesity or also for a prophylactic support of the bone and cartilage structure and for support the joint functions be usable. Furthermore, the nutrient preparation for nutritive supplement, accompanying or supporting Treatment and / or prophylaxis in diseases of the rheumatic type, or diseases caused by age-damaged articular cartilage usable.

Especially the nutrient preparation is suitable in case of osteoarthritis, inflammation joints, swelling, stiffness, restricted mobility, arthritis, thickening or deformities of the joints, malposition of the joints, strong physical Load, overload, Osteoporosis, arthritis, degenerative joint disease, injuries the joints and / or lack of cartilage, for example through malnutrition or lack of exercise.

Farther The nutrient preparation can also be used in Form of a food, for example, as a drink. In preferred embodiments is the nutrient preparation as Granules ago, which is soluble, for example, in water. The nutrient preparation can Of course also in other liquids or drinks like juices be solvable or in food.

Examples of nutrient preparations are given below:
It goes without saying that the preparation forms selected from the group comprising tablets, capsules, powders, granules, solutions, effervescent tablets and / or spray have the customary auxiliaries used for formulating the respective preparation forms, so that in the examples only the effective ones contained Components are listed.

example 1

• – 600 mg Glucosaminsulfat;
• – 400 mg Chondroitinsulfat;
• – 5000 mg Kollagenhydrolysat.

Nutrient preparation comprising 1 sachet of granules with the following substances:

• - 600 mg glucosamine sulphate;
• - 400 mg chondroitin sulfate;
• - 5000 mg collagen hydrolyzate.

Example 2

• – 800 mg Glucosaminsulfat;
• – 600 mg Chondroitinsulfat;
• – 5000 mg Kollagenhydrolysat.

Preparation comprising 1 sachet of granules containing the following substances:

• - 800 mg glucosamine sulphate;
• - 600 mg chondroitin sulfate;
• - 5000 mg collagen hydrolyzate.

Example 3

• – 1200 mg Glucosaminsulfat;
• – 800 mg Chondroitinsulfat;
• – 10000 mg Kollagenhydrolysat.

Preparation comprising 1 granules with the following substances:

• - 1200 mg glucosamine sulfate;
• - 800 mg chondroitin sulfate;
• - 10000 mg collagen hydrolyzate.

Example 4

• – 1500 mg Glucosaminsulfat;
• – 1200 mg Chondroitinsulfat;
• – 10000 mg Kollagenhydrolysat.

Nutrient preparation comprising 1 granules with the following substances:

• - 1500 mg glucosamine sulfate;
• - 1200 mg chondroitin sulfate;
• - 10000 mg collagen hydrolyzate.

Example 5

• – 600 mg Glucosaminsulfat;
• – 400 mg Chondroitinsulfat;
• – 5000 mg Kollagenhydrolysat;
• – 100 mg Vitamin C.

Nutrient preparation comprising 1 sachet of granules with the following substances:

• - 600 mg glucosamine sulphate;
• - 400 mg chondroitin sulfate;
• - 5000 mg collagen hydrolyzate;
• - 100 mg of vitamin C.

Example 6

• – 1500 mg Glucosaminsulfat;
• – 1200 mg Chondroitinsulfat;
• – 10000 mg Kollagenhydrolysat;
• – 500 mg Vitamin C.

Preparation comprising 1 sachet of granules containing the following substances:

• - 1500 mg glucosamine sulfate;
• - 1200 mg chondroitin sulfate;
• - 10000 mg collagen hydrolyzate;
• - 500 mg of vitamin C.

Example 7

• – 1200 mg Glucosaminsulfat;
• – 800 mg Chondroitinsulfat;
• – 10000 mg Kollagenhydrolysat;
• – 200 mg Vitamin C.

Nutrient preparation comprising 1 sachet of granules with the following substances:

• - 1200 mg glucosamine sulfate;
• - 800 mg chondroitin sulfate;
• - 10000 mg collagen hydrolyzate;
• - 200 mg of vitamin C.

Example 8

• – 1500 mg Glucosaminsulfat;
• – 1200 mg Chondroitinsulfat;
• – 10000 mg Kollagenhydrolysat;
• – 200 mg Vitamin C.

Preparation comprising 1 sachet of granules containing the following substances:

• - 1500 mg glucosamine sulfate;
• - 1200 mg chondroitin sulfate;
• - 10000 mg collagen hydrolyzate;
• - 200 mg of vitamin C.

Claims (20)

Nutrient preparation, in particular suitable for nutritive supplementation with increased joint stress and joint diseases, characterized in that the nutrient preparation, based on a daily dose of the nutrient preparation, comprises as effective constituents the following substances: a. Glucosamine and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 600 mg to ≤ 2 g; b. hondroitin and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 400 mg to ≤ 1.5 g; c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g; d. optionally vitamin C in the range of ≥ 100 mg to ≤ 500 mg. Nutrient preparation after Claim 1, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise:  a. Glucosamine and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable Salts in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g glucosamine; b. Chondroitin and / or its Enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg chondroitin; c. Collagen hydrolyzate in the range of ≥ 9 g up to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or d. possibly Vitamin C in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C. Nutrient preparation after Claim 1 or 2, characterized in that glucosamine and / or chondroitin selected in the form of compounds the group comprising their enantiomers, diastereomers, derivatives such as amides or esters, physiologically acceptable salts and / or mixtures thereof. Nutrient preparation after one of the preceding claims, characterized in that glucosamine in the form of compounds selected from the group comprising glucosamine sulfate, glucosamine hydrochloride and / or N-acetyl-glucosamine. Nutrient preparation after one of the preceding claims, characterized in that the physiologically acceptable salt selected from chondroitin is selected from the group comprising chondroitin sulfate and / or chondroitin hydrochloride, preferably selected from the group comprising chondroitin 4-sulfate and / or chondroitin 6-sulfate. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise:  a. Glucosamine sulfate in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g glucosamine sulfate; b. Chondroitin sulfate in the area of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg chondroitin sulfate; c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or d. possibly Vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise: a. Glucosamine hydrochloride in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g glucosamine sulfate; b. Chondroitin hydrochloride in the range of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg chondroitin sulfate; c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or d. possibly Vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise: a. N-acetyl-glucosamine in the range of ≥ 600 mg to ≤ 2 g, preferably in the range of ≥ 800 mg to ≤ 1.5 g, preferably 1.2 g glucosamine sulfate; b. Chondroitin sulfate in Range of ≥ 400 mg to ≤ 1.5 g, preferably in the range of ≥ 600 mg to ≤ 1.2 g, preferably 800 mg chondroitin sulfate; c. Collagen hydrolyzate in the range of ≥ 5 g to ≤ 15 g, preferably in the range of ≥ 9 g to ≤ 12 g, preferably 10 g collagen hydrolyzate; and or d. possibly Vitamin C in the range of ≥ 100 mg to ≤ 500 mg, preferably in the range of ≥ 120 mg to ≤ 230 mg, preferably 200 mg of vitamin C. Nutrient preparation according to one of the preceding claims, characterized in that the nutrient preparation, based on 100 g of the nutrient preparation, comprises as effective constituents the following substances: a. Glucosamine and / or its enantiomers, slides tereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 5 g to ≤ 10 g, preferably 7.5 g; b. Chondroitin and / or its enantiomers, diastereomers, derivatives and / or physiologically acceptable salts in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 4 g to ≤ 8 g, preferably 5.0 g; and / or c. Collagen hydrolyzate in the range of ≥ 20 g to ≤ 80 g, preferably in the range of ≥ 40 g to ≤ 80 g, preferably 62.5 g. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on 100 g of the Nutrient preparation, as active constituents the following substances comprise: a. Glucosamine sulfate in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 5 g to ≤ 10 g, preferably 7.5 g; b. Chondroitin sulfate in the range of ≥ 2 g to ≤ 10 g, preferably in the range of ≥ 4 g to ≤ 8 g, preferably 5.0 g; and or c. Collagen hydrolyzate in the range of ≥ 20 g to ≤ 80 g, preferably in the range of ≥ 40 g to ≤ 80 g, preferably 62.5 g. Nutrient preparation after one of the preceding claims, characterized in that the preparation solid, liquid and / or gel is present, preferably the preparation is in preparation forms selected from the group comprising tablets, capsules, powders, granules, solutions, Effervescent tablets and / or spray before, particularly preferably in the form of Tablets, capsules, effervescent tablets, powders, granules and / or solutions with the same or different composition. Nutrient preparation after one of the preceding claims, characterized in that the preparation in the form of at least one Preparation form, preferably at least two separately present preparation forms, preferably in the form of at least three separately present preparation forms with the same or different composition of substances and / or Substance weight contents is present. Nutrient preparation after one of the preceding claims, characterized in that the preparation in the form of granules is present. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise: a. 600 mg glucosamine sulfate; b. 400 mg chondroitin sulfate; c. 5 g collagen hydrolyzate. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a single dose the nutrient preparation, as active constituents the following substances comprise: a. 600 mg glucosamine sulfate; b. 400 mg chondroitin sulfate; c. 5 g collagen hydrolyzate. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise: a. 1.2 g of glucosamine sulfate; b. 800 mg chondroitin sulfate; c. 10 g collagen hydrolyzate. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a single dose the nutrient preparation, as active constituents the following substances comprise: a. 1.2 g of glucosamine sulfate; b. 800 mg chondroitin sulfate; c. 10 g collagen hydrolyzate. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a daily dose the nutrient preparation, as active constituents the following substances comprise: a. 1.2 g of glucosamine sulfate; b. 800 mg chondroitin sulfate; c. 10 g collagen hydrolyzate; d. 200 mg of vitamin C. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation, based on a single dose the nutrient preparation, as active constituents the following substances comprise: a. 1.2 g of glucosamine sulfate; b. 800 mg chondroitin sulfate; c. 10 g collagen hydrolyzate; d. 200 mg of vitamin C. Nutrient preparation after one of the preceding claims, characterized in that the nutrient preparation is a dietary supplement and / or Food is.