DE102017010930A1 - Topical preparations - Google Patents

Abstract

Topical preparations containing (A) at least one type of carbon particles having an average particle size dso = 650 ± 200 nm, process for their preparation, their use, in particular as cosmetics, care products and products for saunas and steam baths and for the care of skin, mucous membranes, Eyes, ears, mouth, lips, fingernails, toenails, cornea, warts and scars, in excretions of noxa, drugs, toxins, drugs, acids and bases through the skin, lesions, itching, burning, infection and redness, for preventive protection in support of healing processes in existing infections, wounds or burns, in cancer therapy, chemotherapy, skin diseases such as: psoriasis, eczema, acne, eczema, atrophic eczema, warts, rosacea, herpes, shingles, measles, mumps, rubella, chickenpox, hand Mouth and Foot Diseases, Hand and Foot Syndrome, in Decorative Cosmetics, in Cosmetic Face Care, in H caring for people and animals and products containing them.

Description

Field of the invention

The present invention relates to topical preparations.

Furthermore, the present invention relates to a process for the preparation of topical preparations.

Furthermore, the present invention relates to the use of the topical preparations.

Last but not least, the present invention relates to cosmetics, care products, products for saunas and steam baths, powders, solids, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, foams, coatings on textile fabrics, face masks, Gauze, patches and medical devices and components of release materials containing or consisting of the topical preparations.

State of the art

The prior art cited in the present application is incorporated by reference into the present application.

Topical medicines or care products are understood in medicine and cosmetics to mean all those medicines or care products that are not taken or injected, but applied locally. Since local application of the drug is brought directly to the site of action, this can often reduce the dose as much as possible and thus reduce the risk of side effects. All superficial organs, ie the skin and mucous membranes of the respiratory tract, the digestive tract and the external eye are accessible to local treatment or care. But also an injection into a joint is a topical (local, intraarticular) treatment.

• • an der Haut: Salben, Cremes und Lotionen
• • an der Nase: Nasentropfen, -sprays und -salben
• • an der Mundschleimhaut: Gurgellösungen und Lutschtabletten
• • an den Atemwegen: Dosieraerosole, Vernebelung mit UV-Licht und Pulverinhalatoren
• • am Darm: Einläufe und Klistiere
• • an den Bindehäuten der Augen: Tropfen, Salben und Sprays

Particularly in dermatology, topical medicines and care products play a major role, as well as in ophthalmology (ophthalmology) and urology. Among others:

• • on the skin: ointments, creams and lotions
• • on the nose: nose drops, sprays and ointments
• • on the oral mucosa: gargles and lozenges
• • in the respiratory tract: metered aerosols, nebulization with UV light and powder inhalers
• • on the intestine: enemas and enemas
• • on the conjunctiva of the eyes: drops, ointments and sprays

Antibiotics can also be used topically, for example for bacterial skin infections. Sulfonamides are mainly used here.

Nowadays there are many different care products. The term "care products" means, for example, products for hair care, for skin care, oral care and / or nail care. A very good example are care products for the sauna. In the Turkish sauna, also called Hamam, a sauna product is used, which is applied to the skin and includes, among other things, black amber. Furthermore, the skin is often rubbed with salt before the sauna session. This is to help the body with the purification.

The list below lists the individual substance components that are known to be included in each product group.

Basic components

• • emulsifiers
• • film-maker
• • gelling agent
• • solvents
• • oil components
• • soap base
• • surfactants
• • Thickener and / or consistency regulator
• • waxes

hair care

• • anti-dandruff agents
• • Hair bleach and / or bleach enhancer
• • hair dyes
• • Hair-setting polymers
• Hair care and / or conditioners

skin care

• • Antibacterial agents
• • antioxidants
• • antiperspirant active substances and / or astringents
• • Deodorizing agents
• • Skin bleaching agents
• • Cooling agents
• • Moisturizer and / or moisturizer
• • Cleaning body, abrasive and / or polish
• • Refatting substances
• • Self-tanning active ingredients
• • Sunscreen and / or UV filters
• • Active ingredients for skin care
• • active ingredients for chemical hair removal and / or depilation

oral care

• • Antibacterial agents
• • bleach for the teeth
• • Cooling agents
• • Cleaning body, abrasive and / or polish
• • Active ingredients against sensitive teeth
• • active ingredients against dental plaque and / or tooth decay

nail care

• • nail hardener
• • Nagelserum

excipients

• • alkalizing agents, acids and / or neutralizing agents
• • antioxidants
• • binder
• • Dyes / color pigments
• • Humectants
• • Resins
• • preservative
• • oxidizing agent
• • Reducing agent
• • stabilizers
• • propellants for sprays
• • opacifiers / pearlescent substances
• • Denaturants
• • plasticizer

Flavors and / or fragrances

• • Essential oils
• • flavors
• • perfume / fragrances

application areas

• • Decorative cosmetics
• • Facial care
• • Hair care
• • Personal hygiene
• • sunscreen
• • Dental and oral care

The uses of coal are broad and no longer limited to agriculture. More and more new fields of application are integrating coal and using its positive properties.

In his article »55 applications of biochar« in the Ithaka Journal, 1/2012, pages 92 to 102, H.-P. Schmidt discusses the benefits of biochar and gives a detailed description of biochar applications. Here it becomes clear that the applications are not limited to 55 applications of biochar, but rather the entire application areas and possibilities are clarified.

The Utility Model DE 20 2014 010 286 U1 discloses cosmetic cleansing preparations for the skin and / or the hair. These products contain surfactants, activated carbon having a particle size of 0.5 to 60 microns, pearlescing agent and / or at least one structurant selected from the group of Acrcylatcopolymere and alkoxylated thickener, and sodium chloride.

From the Chinese patent application CN 1306825A For example, an absorbent burn ointment is known which contains activated carbon powders of particle size <50 μm, an absorbent ointment matrix and an isotonic regulator. For preparation, the activated carbon is added to an aqueous solution of sodium chloride, after which the water is evaporated. The burn ointment can effectively eliminate the burn wound toxins and prevent the growth of harmful bacteria in the wound. It promotes wound healing and cell proliferation in the wound tissue.

From the American patent application US 2013/0259913 A1 For example, non-oral particles of at least two incompatible hydrophilic and lipophilic substances are known to be produced by the PGSS (Particles from Gas Saturated Solutions) process. Paraffin and microcrystalline wax may be considered as lipophilic material in addition to numerous other materials. Further information on the waxes are not made. The particles may be used in the manufacture of consumer products such as shampoos, personal cleansers, laundry detergents, dishwashing detergents, non-aqueous liquid products, soap bars, paper products, cosmetics, lotions or skin-care agents.

From the American patent application US 2012/0258150 A1 Particles are known that are produced by the PGSS process. The particles have a size of 1 nm to 1 mm, preferably 1 nm to 500 microns and contain a water-insoluble polymer and a volatile material, in particular a perfume or a raw material for perfume. As lipophilic material or water-insoluble polymer, paraffin and microcrystalline wax may be considered in addition to numerous other materials. Further information on the waxes are not made. The particles may be used in the manufacture of consumer products such as shampoos, personal cleansers, laundry detergents, dishwashing detergents, non-aqueous liquid products, soap bars, paper products, cosmetics, lotions or skin-care agents.

From the German patent DE 697 04 925 T2 For example, there is known a cosmetic composition containing a combination of a film-forming polymer with a wax microdispersion. The wax particles preferably have average dimensions of less than 1 μm and preferably less than 0.5 μm. Among other things, organic waxes are used. In addition, the cosmetic composition may contain alkali salts of organic bases and alkylsulfuric acids and alkylsulfonic acids as surfactants and organic pigments such as carbon black.

From the German patent DE 699 17 690 T3 the use of a microdispersion of wax in a cosmetic or dermatological composition is known. Among other things, organic waxes are used. The microdispersion of wax is used as an active ingredient for the prevention and / or treatment of the appearance of wrinkles and / or wrinkles.

From the German Offenlegungsschrift 10 2008 021 007 A1 For example, a microdispersion of waxes containing inorganic particles of carbon allotropes, in particular carbon nanotubes, is known. The microdispersion is used in cosmetics, especially nail varnishes.

From the German patent application DE 10 2012 214 662 A1 is a delayed-release cosmetic composition known. The cosmetic composition contains, based in each case on the particle weight, 30 to 90% by weight of polyalphaolefin waxes and 10 to 70% by weight of one or more cosmetic active ingredients.

From the European patent EP 1 235 546 B1 For example, the use of nanoscale waxes with particle diameters of 10 to 300 nm coated with a protective colloid is known for the preparation of surface active preparations such as hair treatment compositions. Protective colloids used are gelatin, casein, gum arabic, lysalbinic acid, starch, polyvinyl alcohols, polyvinylpyrrolidones, polyalkylene glycols and polyacrylates. The cosmetic preparations may also contain sodium chloride. As a wax, beeswax or sunflower wax is used. In the American patent application US 2017/0027168 A1 , which relates to nanocrystalline products containing mixtures of nanocrystalline cellulose, nanocrystalline polymers and nanocrystalline plastics, is cursed to point out that crystalline nanocellulose can be used in antiviral ointments.

From the American patent application US 2015/0367024 A1 For example, it is known to use hydrogels of nanofibrillar cellulose to prevent and control scarring of scars in wound healing or tissue repair.

From the American patent application US 2017/0000903 A1 The use of gels of crystalline cellulose in the field of cosmetics is known. The gels act as surfactants and can stabilize emulsions.

In the American patent application US 2014/0083416 For example, processes for the production of microcrystalline and nanocrystalline cellulose are described. It is only cursory that the products can be used in food, cosmetics or medicine.

Numerous cosmetics and care products still contain microplastics or microbeads that are not biodegraded, for example as exfoliating particles. Microplasticity is released into the environment, especially in rivers, lakes and seas, where it accumulates in the food chain. (See Umweltbundesamt, Texte 32 - 2016 Microplastics - Development of an Environmental Assessment Concept, Federal Environmental Agency, Texts 63 - 2015 Sources of Microplastics Relevant to Marine Conservation). The cosmetic industry is now anxious to find substitutes for microplastics. For example, materials such as alumina, silica or ground nutshells are suggested as alternatives. For example, shampoos containing phyllosilicates are already common products.

Furthermore, in the European patent application EP 0 563 876 A2 biodegradable microbeads for use in cosmetics and pharmaceuticals. These microbeads can be made by the reaction of glyceraldehyde with natural proteins such as gelatin, albumin and casein.

In the American patent application US 2010/0278882 A1 Protein microbeads are also proposed as ingredients of cosmetics.

From the American patent application US 2014/0026916 A1 A method for reducing pollution in aqueous systems is proposed, which proposes the use of polyhydroxyalkanoate microbeads in personal care products. The polyhydroxyalkanoate microbeads are said to rapidly sink in aqueous systems.

Also conceivable is the use of microbeads based on biodegradable, starch-based thermoplastic polymers, as described in the European patent EP 2 493 975 B1 is described. These products are commercially available under the trademark Solanyl®.

• - Akarizide gegen Milben,
• - Algizide gegen Algen,
• - Fungizide gegen Pilze,
• - mikrobiozide Ausrüstung gegen Keime,
• - Natriumhypochlorit für Haut-/Schleimhaut gegen Viren, Keime, Pilze und Bakterien
• - Nematizide gegen Fadenwürmer und
• - Viruzide gegen Viren.

In order to prevent bacteria and thus pathogens from spreading, cleaning agents, disinfectants and personal care products are mixed with biocides. The following biocides are listed by way of example:

• - acaricides against mites,
• - algicides against algae,
• - fungicides against fungi,
• - microbiocidal equipment against germs,
• - Sodium hypochlorite for skin / mucosa against viruses, germs, fungi and bacteria
• - Nematicides against roundworms and
• - Viruzide against viruses.

Examples of known biocides are 10,10'-oxybisphenoxoarsine (OBPA), octylisothiazolinone (OIT), dichloroctylisothiazolinone (DCOIT), butylbenzisothiazolinone (BBIT), iodocarb (3-iodo-2-propynylbutylcabamate), zinc pyrithione (zinc salt of pyridine-2 thiol-1-oxide), trichlosan (polychlorinated phenoxyphenols), silver ions and silver, especially in the form of silver nanoparticles.

The known biocides have disadvantages such as a narrow range of applications, a comparatively high toxicity, the tendency to cause resistance and cross-resistance and a still largely unexplained ecological long-term effect.

Polyoxometalates (POM) are inorganic polyacids with - in contrast to isopolyacids - at least two different central atoms. Heteropolyacids arise from weak, polybasic oxo acids of a metal (usually chromium, molybdenum, vanadium or tungsten) and a nonmetal (Arsenic, iodine, phosphorus, selenium, silicon or tellurium) as partial mixed anhydrides such as H ₃ [PM ₁₂ O ₄₀ ], in particular 12-molybdophosphoric acid (M = Mo) or 12-tungstophosphoric acid (M = W). The second central atom may also be actinide or lanthanide; The tungsten heteropolyacids are thermally much more stable than the analogous molybdenum compounds. Heterocyclic acids of the general formula [(EO ₄ ) M ₁₂ O ₃₆ ] n- ₈ with n = valence of the tetrahedrally coordinated element E (eg boron, silicon, zinc) are sometimes referred to as Keggin acids. With octahedral coordinated heteroatom, the heterohexametallate type [(EO ₆ ) M ₆ O ₁₈ ] n- ₁₂ (Anderson-Evans anions) is frequently found [cf. Römpp Online, Version 3.47 "Heteropolyacids"].

In her article "Fabrication and Characterization of Antibacterial-active Multilayer Films Based on Keggin Polyoxometalates and Methylene Blue", in Z. Naturforsch. 2010, 65b, pages 140-146, describe Dan Chen, Jun Peng, Haijun Pang, Pengpeg Zhang, Yuan Chen, Yan Shen, Chanyung Chen, and Huiyuan Ma, multi-layer films based on kegging polyoxymetalates alpha [SiW ₁₂ O ₄₀ ] ^4- / alpha [PMo ₁₂ O ₄₀ ] ^3- , which show antibacterial activity against Escherichia coli.

In their article "Antibacterial activity of highly negatively charged polyoxotentates, K ₂₇ (KAs ₄ W ₄₀ O ₁₄₀ ) and K ₁₈ (KSb ₉ W ₂₁ O ₈₆ ), and Keggin-structural polyoxotungstates against Helicobacter pylori", in Journal of Inorganic Biochemistry, 99 (2005), pages 1023 to 1031, Miyao Inoue, Keiko Segawa, Sae Matsunaga, Obuhiro Matsmoto, Mayumi Oda and Toshihiro Yamase describe the antibacterial activity of this polyoxymetalate (POM) based on determination of minimum inhibitory concentration (MIC) and fractional inhibitory concentration (FIK), the time of death of the bacteria, the bacterial morphology and the uptake of POM in the bacterial cells.

From the American patent US 6,911,470 B1 POM are known to have antiretroviral activity.

From the American patents US 5,824,706 and US 6,020,369 are the prevention and treatment of respiratory viral infections known in which a POM-containing aerosol spray is applied to the lungs.

From the American patent application US 2008/0187601 A1 and the American patents US 6,723,349 B2 and US Pat. No. 7,097,858 B2 are topical POM-containing compositions are known by means of which pollutants, in particular warfare agents, are removed from the environment. Additionally, the topical compositions may still contain cerium, silver, gold, or platinum compounds. In particular, perfluoropolyethers (PFPE) can be used as the carrier. Thus, the warfare agent 2-chloroethylethyl sulfide (CEES) can be quantitatively oxidized to 2-chloroethylethyl sulfoxide (CEESO). These known topical compositions have the disadvantage that they can not be removed from the skin by water.

From the American patent US 5,904,734 For example, a bleaching agent containing peroxide and an activator is known. The activator may be tungsten silicic acid. The bleach can remove mold and fungus from tiles and curtains.

From the Japanese patent application JP 002005281299 A For example, the use of potassium salt of 12-silicotungstic acid as an antibacterial and antifungal agent for use in furniture coating compositions is known.

In the article by Eunyoung Bae, Jae Won Lee, Byeong Hee Wang, Jiman Yeo, Jecong Yoon, Hyung Joon Cha and Wonyong Choi "Photocatalytic bacterial inactivation by polyoxometalates", in Chemosphere 72 (2008), 174-181, the photocatalytic inactivation becomes of Gram-negative and Gram-positive bacteria. For this purpose, aqueous suspensions of the bacteria containing H ₄ SiW ₁₂ O ₄₀ or H ₃ PW ₁₂ O _{40 were} irradiated with UV light. The authors conclude that the polyoxometalates act as photocatalysts.

From the American patent application US 2009/0004124 A1 For example, cosmetic compositions containing fluidized particles such as H ₃ PW ₁₂ O ₄₀ are known. The fluidization of the particles is carried out by residues of long carbon chains, which are linked to the particles.

From the American patent application US 2009/0012204 A1 For example, polymers functionalized with reactive polyoxometalates are known which serve to decontaminate harmful compounds. As polyoxometalates, those of the Keggin type of the general formula (R ^{m +} ) _y [X ^{n +} M ₁₂ O ₄₀ ] ^{(8-n) -} , wherein m and n are integers, y = (8-n) / m, X = Phosphorus or silicon and M = molybdenum, tungsten, vanadium and mixtures thereof, O = oxygen and R = hydrogen, silver, ammonium, quaternary ammonium and mixtures thereof.

From the American patent application US 2009/0022645 A1 is the use of K ₄ [α-SiW ₁₂ O ₄₀ ] known as an activator for bleaching.

From the German patent application DE 10 2015 000 812 A1 Hydrous cleaning and personal care products with biocidal effect are known to contain polyoxometalates as a biocidal ingredient.

Dis is further from the German patent application DE 10 2015 000 813 A1 A method of destroying drugs and toxins and their metabolites using polyoxometalate micro and / or nanoparticles.

In the publication "Hair follicles as a target structure for nanoparticles" by J. Lademann, F. Knorr, H. Richter, S. Jung, MC Meinke, E. Rühl, U. Alexiev, M. Calderon and A. Patzelt, Journal of Innovative Optical Health Sciences, Vol. 8, No. 4 (2015) 1530004, the authors study the penetration of titanium dioxide nanoparticles into hair follicles. They conclude that titanium dioxide nanoparticles with a mean particle size d ₅₀ of 643 nm have the greatest penetration depth between 1100 μm and 1200 μm.

Object of the present invention

The present invention was based on the object cosmetics, toiletries, products for saunas and steam baths, powders, solids, gels, creams, ointment lotions, drops, sprays, metered aerosols gargles, lozenges, enemas, enemas, suppositories, foams toilet utensils, textile fabrics To provide face masks, envelopes, bandages, tampons, gauze, plasters, medical devices and release materials which function, inter alia, as a moisture regulator and / or as a water reservoir, inorganic and / or organic substances that are on, in and / or under the reside, bind, absorb and / or render harmless to human or animal skin, suppress the formation of unpleasant odors and / or inhibit unhealthy bacteria and promote healthy bacteria.

The aforementioned products are said to be of advantage as medical, especially oncological and dermatological, cosmetics and care products, products for saunas and steam baths and for the care of the skin, mucous membranes, especially mucous membranes in the mouth, on and in the genitals and in the intestine, eyes, ears , Mouth, lips, fingernails, toenails, cornea, warts and scars, in excretions of noxa, drugs, toxins, drugs, acids and bases over the skin, in lesions, itching, burning, intertrigo, infections and redness, for preventive protection, to be used to assist healing processes in existing infections, wounds or burns, in decorative cosmetics, in cosmetic facial care, in hair care and in the personal care of humans and animals.

Furthermore, the above-mentioned products should not harm the environment and in particular do not accumulate in the marine food web in organisms.

In addition, it is an object of the present invention to find a process for the preparation of the aforementioned products.

Inventive solution

1. (A) mindestens einen Typ von Kohlenstoffpartikeln einer mittleren Teilchengröße von d₅₀ = 650 ± 200 nm,

gefunden, die im Folgenden als »erfindungsgemäße topische Zubereitungen« bezeichnet werden. Accordingly, the topical preparations containing

1. (A) at least one type of carbon particles having an average particle size d ₅₀ = 650 ± 200 nm,

which are referred to below as "topical preparations according to the invention".

1. (I) mindestens einen Typ von Partikeln (A) mit mindestens einem weiteren Bestandteil vermischt und die resultierende Mischung homogenisiert und
2. (II) die resultierende homogenisierte Mischung zu Pulvern, Festkörpern, Gelen, Cremes, Salben, Lotionen, Tropfen, Sprays, Dosieraerosolen, Gurgellösungen, Lutschtabletten Einläufen, Klistieren, Zäpfchen oder Schäumen verarbeitet und/oder auf und/oder in textile Gewebe, Gesichtsmasken, Verbandsmull, Umschläge, Binden, Tampons, Pflaster, medizinische Geräte und/oder Releasematerialien appliziert,

und das im Folgenden als »erfindungsgemäßes Verfahren« bezeichnet wird.In addition, the process for the preparation of the topical preparations according to the invention was found in which

1. (I) at least one type of particles (A) mixed with at least one further component and the resulting mixture homogenized and
2. (II) the resulting homogenised mixture is processed into powders, solids, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenge enemas, enemas, suppositories or foams and / or on and / or in textile fabrics, face masks, Applied gauze, envelopes, bandages, tampons, plasters, medical devices and / or release materials,

and which is hereinafter referred to as "inventive method".

Furthermore, the use of the topical preparations according to the invention as medical and decorative cosmetics, care products and products for saunas and steam baths and for the care of skin, mucous membranes, eyes, ears, mouth, lips, fingernails, toenails, cornea, warts and scars, in excretions of noxious substances, drugs, toxins, medicines, acids and bases via the skin, in the case of lesions, itching, burning, intertrigo, infections and redness, for preventive protection, to support healing processes in existing infections, wounds or burns, in decorative cosmetics, in the cosmetic facial care, in the hair care and in the personal care of humans and animals, which is referred to below as "inventive use".

Not least the medical and decorative cosmetics, care products, products for saunas and steam baths, powders, solids, gels, creams, ointments, lotions, drops, sprays, metered aerosols gargles, lozenges, enemas, enemas, suppositories, foams and toilet utensils, textile fabrics , Face masks, envelopes, bandages, tampons, gauze, plasters, medical devices and release materials, which contains or consists of at least one topical preparation according to the invention and the following are referred to as "products according to the invention".

Advantages of the invention

In view of the prior art, it was surprising and unforeseeable for the skilled person that the object underlying the present task could be achieved by means of the topical preparations according to the invention, the method according to the invention, the use according to the invention and the products according to the invention.

In particular, it was surprising that the medical and decorative cosmetics, toiletries, products for saunas and steam baths, powders, solids, gels, creams, ointment lotions, drops, sprays, metered aerosols gargle solutions, lozenges, enemas, enemas, suppositories, foams toilet utensils, textile Tissues, facemasks, envelopes, sanitary napkins, tampons, gauze, plasters, medical devices and release materials have functioned well as moisture regulators and / or water storages, inorganic and / or organic substances located on, in and / or under human or animal skin , bind, absorb and / or render harmless, suppress the formation of unpleasant odors and / or inhibit unhealthy bacteria and promote healthy bacteria.

According to the invention, the products according to the invention could advantageously be used as medical, in particular oncological and dermatological, cosmetics and care products, products for saunas and steam baths and for the care of skin, mucous membranes, in particular mucous membranes in the mouth, on and in the genitals and in the intestine, eyes, ears, Mouth, lips, fingernails, toenails, cornea, warts and scars, in excretions of noxa, drugs, toxins, medicines, acids and bases over the skin, in lesions, itching, burning, intertrigo, infections and redness, for preventive protection, for Assist healing processes in existing infections, wounds or burns, in decorative cosmetics, in cosmetic facial care, in hair care and in the personal care of humans and animals.

Furthermore, the topical preparations according to the invention and the products according to the invention could be prepared in a simple and very reproducible manner by the method according to the invention.

It was particularly surprising that in the production of the products according to the invention and the topical preparations according to the invention, it was possible to use largely or exclusively renewable, compostable, toxicologically acceptable, biodegradable and / or recyclable raw materials, so that the production and use of the topical preparations according to the invention and the products according to the invention were particularly environmentally friendly and could act as a carbon sink.

Particularly surprising was the binding and / or absorption of pollutants from the skin by the topical preparations according to the invention and the products according to the invention. In particular, drugs secreted by the skin and mucous membranes, especially cytostatics, were prevented from reabsorbing and rendering harmless. Thus, the topical preparations according to the invention and the products according to the invention were tolerable for allergy sufferers and / or for all skin types. In addition, they were bacteriostatic and had an antiviral, fungicidal or fungistatic and nematicidal action.

All these advantageous effects of the topical preparations according to the invention and of the products according to the invention were enhanced by their excellent penetration into the skin and into the mucous membranes. They could therefore serve as carriers for drugs.

Furthermore, it was surprising that the preparation of the products according to the invention could be carried out free of polycyclic aromatic compounds (PAH).

Detailed description of the invention

The first essential constituent of the topical preparations according to the invention is at least one type, in particular one type, of carbon particles (OH) having an average particle size d ₅₀ = 650 ± 200 nm, preferably 650 ± 150 nm and in particular 650 ± 100 nm.

The charcoal particles (A) may consist of charcoal and / or their screenings and / or wood ash, activated carbon, hard coal, animal charcoal, animal waste coal, pyrogenic carbon of different pyrolysis degree, functionalized carbon and / or functionalized coal, pretreated coal, washed coal, coal with different degrees of charring, Extracted coal coke, natural coke and incompletely outgassed coke and / or obtained by a pyrolysis process in a mobile or stationary pyrolysis of predominantly lignin-rich, organic materials such as wood, plant stems, leaves, fruit pits, nut shells and / or bones. Bones have the advantage that they are particularly phosphorus-containing.

Preferably, the pyrolysis process is operated under oxygen exclusion at about 1000 ° C. However, the person skilled in the art understands how to adapt the pyrolysis conditions to the particular circumstances, such as the type of pyrolysis plant, the ambient pressure and / or the amount of the type and nature of the pyrolysis product. These materials are common and known and go, for example, from the German patent application DE 10 2015 010 041 A1 Paragraphs [0055] to [0064].

The coal produced by various processes has intramolecular carbon structures, e.g. can be influenced by the pyrolysis conditions. Thereby, the properties of the carbon used for the process according to the invention can be adapted in view of a high nutrient and water storage capacity.

The carbon particles (A) can have a wide variety of morphologies and geometric shapes, so that they can be excellently adapted to the other constituents of the topical preparations according to the invention.

Thus, they can be compact, and have at least one cavity and / or a core-shell structure. In addition, these cavities can be different in size. You can also use different geometric shapes, such as spheres, ellipsoids, cubes, cuboids, pyramids, cones, cylinders, rhombuses, dodecahedra, truncated dodecahedron, meander, fractal, icosahedron, truncated icosahedron, dumbbells, tori, platelets, or needles with circular, oval , elliptical, square, triangular, quadrangular, pentagonal, hexagonal, heptagonal, octagonal, or star-shaped (tri, tetra, pentagonal, or polygonal) outline. If necessary, existing edges and corners can be rounded. It is also possible for two or more carbon particles (A) of different morphology and / or geometric form to be combined. For example, but not by way of limitation, spherical carbon particles (A) may have pointed outgrowths in the form of cones. Furthermore, their surface may have depressions so that the carbon particles (A) have a strawberry or raspberry morphology. Last but not least, the dumbbell, tori, needles or plates can be bent in at least one direction of the room. They can be freely selectable in any form.

The average particle size d _{50 of} the carbon particles (A) varies between the limits given above. The carbon particles (A) may be monodisperse, oligodisperse and / or polydisperse and therefore are excellently adapted to the particular intended use of the topical preparations according to the invention.

The median particle size d ₅₀ can be measured by transmission electron microscopy (TEM), scanning electron microscopy (SEM), scanning transmission electron microscopy (RTEM), atomic force microscopy (AFM), or scanning tunneling microscopy (TRM). It can be set to the desired value using standard and well-known screening methods.

Preferably, the carbon particles (A) have largely free or completely free surfaces.

The amounts of carbon particles (A) used in the topical preparations according to the invention can vary very widely and depend mainly on their intended use. Preferably, the amounts used are from 0.01 to 20 wt .-%, preferably 0.05 to 18 wt .-% and in particular 0.1 to 15 wt .-%, each based on the total amount of a given inventive topical preparations. For special applications, higher dosages can also be used.

Particularly advantageous topical preparations according to the invention comprise particles (B) having an average particle size d ₅₀ equal to 10 nm to <1000 μm, preferably 20 nm to 1000 nm, preferably 30 nm to 800 nm and in particular 40 nm to 600 nm. The particles (B) contain and / or consist of at least one, in particular one, type of nanocrystalline and / or microcrystalline natural waxes and / or semisynthetic waxes based on natural waxes and / or biodegradable microplastics.

The term wax is a phenomenology term for a series of naturally or synthetically or synthetically obtained substances, which generally have the following properties: kneadable at 20 ° C, solid to brittle-hard, coarse to fine crystalline, translucent to opaque, non-glassy, melting above 40 ° C without decomposition, but already slightly above the melting point relatively low viscosity and generally or advantageously not stringy, have a strong temperature-dependent consistency and solubility and are polishable under light pressure. If more than one of the above-mentioned properties is not met, this substance is not wax according to the DGF (German Society for Fat Science) (see DGF unit method M-I 1 (75)). Waxes differ from similar synthetic or natural products such as resins, plastic masses, metal soaps, etc. mainly in that they generally in the molten, low-viscosity state between about 50 ° C and 90 ° C, in exceptional cases up to about 200 ° C. pass over and are virtually free of ash forming compounds. Waxes form pastes or gels and usually burn with a sooting flame.

Further details on the concept of waxes can be found in Römpp Chemielexikon, 10th edition, Volume 6.1999, Georg Thieme Verlag Stuttgart / New York, page 4.9.2006, keyword: "waxes" and the literature reviewed there, especially Cos. Toil. 101, 49 (1986 and DGF standard methods, Department M waxes and wax products, 7th supplement delivery, 05/1999, Stuttgart.

According to the invention, preference is given to using a wax (B) which contains polar functional groups, in particular groups which contain heteroatoms from the group of oxygen, nitrogen and / or sulfur, preferably oxygen, particularly preferably hydroxyl groups, polyether groups, in particular polyethylene oxide groups, and / or carboxyl groups.

Examples of suitable natural waxes are vegetable waxes such as candelilla wax, carnauba wax, Japan wax, esparto wax wax, cork wax, guaruma wax, rice germ oil wax, sugarcane wax, ouricury wax, montan wax, absolute flower waxes, cuba palm wax, cotton wax, flax wax, peat wax, rose wax, jasmine wax, peethawax, myrtle wax and waxy wax ,

Examples of suitable natural waxes are animal waxes such as spermaceti, wool wax, shellac, china wax, beeswax and ragwort wax.

Examples of suitable natural waxes are mineral waxes such as ceresin and ozokerite.

Examples of suitable modified natural waxes are hard waxes, montan ester waxes, Sasol waxes, hydrogenated jojoba waxes, wool wax alcohols (Eucerit), and modified beeswaxes (Cerabellina).

Bees waxes, Cerabellina and absolute flower waxes are particularly preferably used.

Preferably, the wax particles (B) are formed from natural and semi-synthetic waxes by the Gas Antisolvent Recrystallization (GAS) method, the PCA (Precipitation with a Compressed Fluid Antisolvent) method, the Particles from Gas Saturated Solutions (PGSS) method or the RESS Process (Rapid Expansion of Supercritical Solutions) (see, for example, US patent applications US 2012/0258150 A1 and US 2013/0259913 A1 ).

Instead of the wax particles (B) or in addition to these, the topical preparations according to the invention may contain biodegradable and non-degradable microplastics or microbeads, which, however, is less preferred according to the invention. If non-biodegradable microplastics is used, their amount should be kept as low as possible.

Suitable biodegradable microbeads (B) are for example from American Patent Application 2014/0026916 A1 known. They have a mean particle size d ₅₀ <400 microns and consist of polyhydroxyalkanoates. Polyhydroxyalkanoates (PHA) or polyhydroxy-fatty acids (PHF) are naturally occurring water-insoluble and linear polyesters, which are formed by many bacteria as a reserve for carbon and energy. In nature, they are made by fermenting sugar or fats. These biopolymers are biodegradable and are used to make bioplastics. It has the advantage that they sink to the bottom in water and biodegrade.

Further suitable biodegradable microbeads (B) are known, for example, from the American patent application US 2010/0278882 A1 known. They consist of crosslinked proteins such as silk proteins and have a mean particle size d ₅₀ of 0.1 .mu.m to 100 .mu.m.

Further suitable biodegradable microbeads (B) are furthermore from the European patent application EP 0 563 876 A2 known. They are made by cross-linking natural proteins such as gelatin, albumin and casein with glyceraldehyde as a cross-linking agent.

The average particle size d _{50 of} the wax particles (B) and / or of the biodegradable microbeads (B) can vary widely and thus be perfectly adapted to the requirements of the individual case. The mean particle size d ₅₀ is preferably between 1 μm and <1000 μm, preferably 10 μm to 700 μm, particularly preferably 50 μm to 500 μm and in particular 100 μm to 300 μm.

The wax particles (B) and / or the biodegradable microbeads (B) can be protected by protective colloids from aggregation or agglomeration. Protective colloids are usually water-soluble, preferably biodegradable, polymers such as partially saponified polyvinyl acetate, polyvinyl alcohol, polyvinylpyrrolidone, cellulose ethers (Tylose) such as methylcellulose, hydroxyethylcellulose, hydroxypropylmethylcellulose, starch, proteins, alginates, pectins and gelatin.

The content of the topical formulations according to the invention on wax particles and / or biodegradable microbeads (B) can vary widely and can thus be adapted excellently to the respective intended use. Preferably, a given topical preparation according to the invention, based on its total amount, contains 0.1% by weight to 50% by weight, 0.5% to 45% by weight and in particular 1% by weight to 40% by weight of wax particles (B).

Further advantageous topical preparations according to the invention contain particles (C) of an average particle size d ₅₀ of 10 nm to <1000 nm, preferably 300 nm to 900 nm, preferably 650 ± 200 nm and in particular 650 ± 100 nm. They contain at least one type and / or consist of at least one type of nanocrystalline, nanofibrillar, microcrystalline and / or microfibrillar polysaccharides. In particular, cellulose nanofibers (CNF), microfibrillar celluloses (MFC), microcrystalline celluloses (MCC), nanofibrillary polysaccharides (NFP), nanocrystalline celluloses (CNC), bacterial nanocelluloses (BNC) and papermaking paper pulp and fiber paper pulp and fiber debris, and waste textiles particles, used.

The content of the topical preparations according to the invention on particles (C) can vary widely and can be adapted excellently to the respective intended use. Preferably, a given topical preparation according to the invention contains, based on its total amount, from 0.01% by weight to 10% by weight, preferably from 0.02% by weight to 9% by weight and in particular from 0.03 to 8% by weight. -%.

Still further advantageous topical preparations according to the invention contain (D): heteropolyacids and isopolyacids and their isomers, defect structures and partial structures, collectively called polyoxometalates (POM), in the form of their molecules having a largest molecular diameter ≦ 2 nm, preferably ≦ 1.5 nm and in particular ≦ 1 nm, collectively called POM molecules, and in the form of microparticles and nanoparticles having an average particle size of 1 nm to <1000 μm, preferably 2 nm to 500 μm, preferably 5 nm to 250 μm, especially preferably 5 nm to 150 μm and in particular 5 nm to 100 μm. In the following, they will be referred to as "POM microparticles or POM nanoparticles", respectively.

It should be emphasized that the data ≤ 2 nm, ≤ 1.5 nm and ≤ 1 nm do not include a molecular diameter of 0 nm, but that the lower limit of the molecular diameter is equal to the largest diameter of the smallest existing POM molecule.

The mean particle size of the POM microparticles to be used according to the invention and POM nanoparticles measured by transmission electron microscopy (TEM), scanning electron microscopy (SEM), scanning transmission electron microscopy (RTEM), atomic force microscopy (AFM) or scanning tunneling microscopy (TRM) can vary very widely and meet the requirements of the invention To be adjusted individually.

The POM microparticles and POM nanoparticles can have a wide variety of morphologies and geometric shapes, so that they can also be perfectly adapted to the requirements of the individual case in this respect.

Thus, they can be compact and have at least one cavity and / or a core-shell structure, wherein the core and the shell can be constructed of different materials. They may also have different geometric shapes such as spheres, ellipsoids, cubes, cuboids, pyramids, cones, cylinders, rhombuses, dodecahedra, truncated dodecahedra, icosahedra, truncated icosahedra, dumbbells, tori, platelets or needles with circular, oval, elliptical, square, triangular , quadrangular, pentagonal, hexagonal, heptagonal, octagonal, or star-shaped (tri-quad, quadrilateral, pentagonal, or polygonal) outline. If necessary, existing edges and corners can be rounded. It is also possible for two or more POM microparticles and / or POM nanoparticles of different morphology and / or geometric form to assemble together. For example, spherical POM microparticles and / or POM nanoparticles may have pointed outgrowths in the form of cones. Or, two or three cylindrical POM microparticles and / or POM nanoparticles may assemble to form a T-shaped or Y-shaped particle. Furthermore, their surface may have pits so that the POM microparticles and / or POM nanoparticles have a strawberry, raspberry or blackberry morphology. Last but not least, the dumbbells, tori, needles or plates can be bent in at least one direction of the room.

The diameter of the POM microparticles and POM nanoparticles can vary widely and therefore be perfectly adapted to the requirements of the individual case.

In the context of the present invention, the diameter of the POM microparticles and / or POM nanoparticles to be used according to the invention, which have no spherical shape, is equal to the longest distance traveled by the respective POM microparticles and POM nanoparticles.

Preferably, the diameter of preferred nanoparticles according to the invention is 1 nm to <1000 .mu.m, preferably 2 nm to 500 .mu.m, preferably 5 nm to 250 .mu.m, more preferably 5 nm to 150 .mu.m and in particular 5 nm to 100 microns.

The elemental composition and structure of the POM can also vary very widely.

• - das Lindquist-Hexamolybdatanion, M0₆O₁₉ ^2-,
• - das Decavanadatanion, V₁₀O₂₈ ^6-,
• - das Paratungstatanion B, H₂W₁₂O₄₂ ^10-,
• - Mo36-Polymolybdate, Mo₃₆O₁₁₂(H₂O)^8-,
• - die Strandberg-Struktur, HP₂Mo₂O₂₃ ^4-,
• - die Keggin-Struktur, XM₁₂O₄₀ ^n-,
• - die Dawson-Struktur, X₂M₁₈O₆₂ ^n-,
• - die Anderson-Struktur, XM₆O₂₄ ^n-,
• - die Allman-Waugh-Struktur, X₁₂M₁₈O₃₂ ^n-,
• - die Weakley-Yamase- Struktur, XM₁₀O₃₆ ^n-, und
• - die Dexter-Silverton-Struktur, XM₁₂O₄₂ ^n-.

For example, the classification of the POM into the following structures is known:

• the Lindquist hexamolybdate anion, M0 ₆ O ₁₉ ^2- ,
• the decavanadate anion, V ₁₀ O ₂₈ ^6- ,
• the paratization stat B, H ₂ W ₁₂ O ₄₂ ^10- ,
• Mo36 polymolybddate, Mo ₃₆ O ₁₁₂ (H ₂ O) ^8- ,
• - the Strandberg structure, HP ₂ Mo ₂ O ₂₃ ^4- ,
• the Keggin structure, XM ₁₂ O ₄₀ ^n- ,
• the Dawson structure, X ₂ M ₁₈ O ₆₂ ^n- ,
• the Anderson structure, XM ₆ O ₂₄ ^n- ,
• - the Allman Waugh structure, X ₁₂ M ₁₈ O ₃₂ ⁿ ,
• the Weakley-Yamase structure, XM ₁₀ O ₃₆ ⁿ , and
• - the Dexter-Silverton structure, XM ₁₂ O ₄₂ ^n- .

The n-prime number here is an integer from 3 to 20 denoting the valence of an anion that varies depending on the variables X and M.

As a further principle of order for POM the formulas I to XIII can serve:
- (BW ₁₂ O ₄₀ ) ^5- (I), - (W ₁₀ O ₃₂ ) ^4- (II), - (P ₂ W ₁₈ O ₆₂ ) ^6- (III), - (PW ₁₁ O ₃₉ ) ^7- (IV), - (SiW ₁₁ O ₃₉ ) ^8- (V), - (HSiW ₉ O ₃₄ ) ^9- (VI), - (HPW ₉ O ₃₄ ) ^8- (VII), - (TM) ₄ (PW ₉ O ₃₄ ) ^t- (VIII), - (TM) ₄ (P ₂ W ₁₅ O ₅₆ ) ₂ ^t- (IX), - (NaP ₅ W ₃₀ O ₁₁₀ ) ^14- (X), - (TM) ₃ (PW ₉ O ₃₄ ) ₂ ^12- (XI) and - (P ₂ W ₁₈ O ₆ ) ^6- (XII).

In formulas I to XII, TM is a divalent or trivalent transition metal ion such as Mn ²⁺ , Fe ²⁺ , Fe ³⁺ , Co ²⁺ , Co ³⁺ , Ni ²⁺ , Cu ²⁺ and Zn ²⁺ . The superscript t is an integer and denotes the valence of an anion, which varies depending on the significance of the variable TM.

Furthermore, POM of general formula XIII come into consideration: - (A _x Ga _y Nb _a O _b ) ^z- (XIII).

In the formula XIII the variable A stands for phosphorus, silicon or germanium and the index x stands for 0 or for an integer from 1 to 40. The index y stands for an integer from 1 to 10, the index a stands for one integer from 1 to 8 and the index b is an integer from 15 to 150. The z factor varies depending on the nature and the degree of oxidation of the variable A. The aqua complexes and the active fragments of the POM XIII are also suitable.

When the index x is 0, y is preferably 6-a, where the index a is an integer of 1 to 5 and the index b is 19.

When the variable A is silicon or germanium, the index x is 2, the index y is 18, the index a is 6 and the index b is 77.

When the variable A is P, the index x is 2 or 4, the index y is 12, 15, 17 or 30, the index a is 1, 3 or 6 and the index b is 62 or 123.

In addition, the isomers of POM come into consideration. Thus, the keggin structure has five isomers, the alpha, beta, gamma, delta, and epsilon structure. Furthermore, defect structures or lacunary structures as well as partial structures can be considered.

Preferably, the anions I to XIII are applied in the form of salts with cations which are approved for cleansing and personal care and pharmaceutical use.

Examples of suitable cations are

• H ⁺ , Na ⁺ , K ⁺ and NH ₄ ⁺ ,
• Mono-, di-, tri- or tetra- (C ₁ -C ₂₀ -alkylammonium) such as pentadecyldimethylferrocenylmethylammonium, undecyldimethylferrocenylmethylammonium, hexadecyltrimethylammonium, octadecyltrimethylammonium, didodecyldimethylammonium, ditetradecyldimethylammonium, dihexadecyldimethylammonium, dioctadecyldimethylammonium, dioctadecylviologen, trioctadecylmethylammonium and tetrabutylammonium;
• - Mono-, di-, tri- or tetra- (C ₁ -C ₂₀ alkanolammonium) such as ethanolammonium diethanolammonium and triethanolammonium
• Monocations of naturally occurring amino acids such as histidinium (HISH ⁺ ), argininium (ARGH ⁺ ) or lysinium (LYSH ⁺ ) or oligo- or polypeptides having one or more protonated basic amino acid residues.

[See. US 6,020,369, column 3, line 6, to column 4, line 29]

Also included are natural, modified natural and synthetic cationic oligomers and polymers, i.e., oligomers and polymers bearing primary, secondary, tertiary and quaternary ammonium groups, primary, secondary and tertiary sulfonium groups and / or primary, secondary and tertiary phosphonium groups. Synthetic oligomers and polymers are common and well known and are used, for example, in electrodeposition paints. Examples of natural cationic oligomers and polymers are polyamino-saccharides such as polyglucosamines, especially chitosan.

• a) vgl. US 6,020,369 , TABLE 1, Spalten 3 bis 10;
• b) Tierui Zhang, Shaoquin Liu, Dirk G. Kurth und Charl F. J. Faul, »Organized Nanostructured Complexes of Polyoxometalates and Surfactants that Exhibit Photoluminescence and Electrochromism, Advanced Functional Materials, 2009, 19, Seiten 642 bis 652 ;
• n Zahl, insbesondere ganze Zahl, von 1 bis 50.

Examples of suitable POM are shown in Table 1. Table 1: Sum formulas of suitable POM No. Molecular formula family structure 1 [(NMP) ₂ H] ₃ PW ₁₂ O ₄₀ 2 [(DMA) ₂ H] ₃ PMo ₁₂ O ₄₀ 3 (NH ₄ ) ₁₇ Na [NaSb ₉ W ₂₁ O ₈₆ ] Inorganic crypt 4 a- and bH ₅ BW ₁₂ O ₄₀ " 5 a- and bH ₆ ZnW ₁₂ O ₄₀ " 6 a and bH ₆ P ₂ W ₁₈ O ₆₂ " 7 alpha- (NH ₄ ) ₆ P ₂ W ₁₈ O ₆₂ Wells-Dawson structure 8th K ₁₀ Cu ₄ (H ₂ O) ₂ (PW ₉ O ₃₄ ) ₂ .20H ₂ O " 9 K ₁₀ Co ₄ (H ₂ O) ₂ (PW ₉ O ₃₄ ) ₂ .20H ₂ O " 10 Na ₇ PW ₁₁ O ₃₉ " Na ₇ PW ₁₁ O ₃₉ .20H ₂ O + 2 C ₆ H ₅ P (O) (OH) ₂ " 11 [(n-butyl) ₄ N] ₄ H ₃ PW ₁₁ O ₃₉ " 12 b-Na ₈ HPW ₉ O ₃₄ " 13 [(n-butyl) ₄ N] ₃ PMoW ₁₁ O ₃₉ " 14 a - [(n-butyl) ₄ N] ₄ Mo8O26 " 15 [(n-butyl) ₄ N] ₂ W ₆ O ₁₉ " 16 [(n-butyl) ₄ N] ₂ Mo ₆ O ₁₉ " 17 a- (NH ₄ ), H _(4-n) SiW ₁₂ O ₄₀ " 18 a- (NH ₄ ) _n H ( _5-n ) BW ₁₂ O ₄₀ " 19 AK ₅ BW ₁₂ O ₄₀ " 20 K ₄ W ₄ O ₁₀ (O ₂ ) ₆ " 21 b-Na ₉ HSiW ₉ O ₃₄ " 22 Na ₆ H ₂ W ₁₂ O ₄₀ 23 (NH ₄ ) ₁₄ [NaP ₅ W ₃₀ O ₁₁₀ ] Preyssler structure 24 a- (NH ₄ ) ₅ BW ₁₂ O ₄₀ " 25 a-Na ₅ BW ₁₂ O ₄₀ " 26 (NH ₄ ) ₄ W ₁₀ O ₃₂ " 27 (Me ₄ N) ₄ W ₁₀ O ₃₂ " 28 (HISH ⁺ ) _n H _(5-n) BW ₁₂ O ₄₀ " 29 (LYSH ⁺ ) _n H _(5-n) BW ₁₂ O ₄₀ " 30 (ARGH ⁺ ) _n H _(5-n) BW ₁₂ O ₄₀ " 31 (HISH ⁺ ) _n H _(4-n) SiW ₁₂ O ₄₀ " 32 (LYSH ⁺ ) _n H _(4-n) SiW ₁₂ O ₄₀ " 34 (ARGH ⁺ ) _n H _(4-n) SiW ₁₂ O ₄₀ " 35 K ₁₂ [EuP ₅ W ₃₀ O ₁₁₀ ] .22H ₂ O ^b) " 36 AK ₈ SiW ₁₁ O ₃₉ " 37 K ₁₀ (H ₂ W ₁₂ O ₄₂ ) " 38 K ₁₂ Ni ₃ (II) (PW ₉ O ₃₄ ) ₂ .nH ₂ O " 39 (NH ₄ ) ₁₀ CO ₄ (II) (PW ₉ O ₃₄ ) ₂ .nH ₂ O " 40 K ₁₂ Pd ₃ (II) (PW ₉ O ₃₄ ) ₂ . nH ₂ O " 41 Na ₁₂ P ₂ W ₁₅ O ₅₆ .18H ₂ O Lacunare (defective) structure 42 Na ₁₆ Cu ₄ (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O " 43 Na ₁₆ Zn ₄ (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O " 44 Na ₁₆ Co ₄ (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O " 45 Na ₁₆ N _i4 (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O Wells-Dawson sandwich structure 46 Na ₁₆ Mn ₄ (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O " 47 Na ₁₆ Fe ₄ (H ₂ O) ₂ (P ₂ W ₁₅ O ₅₆ ) ₂ .nH ₂ O " 48 K ₁₀ Zn ₄ (H ₂ O) ₂ (PW ₉ O ₃₄ ) ₂ .20H ₂ O Keggin sandwich structure 49 K ₁₀ Ni ₄ (H ₂ O) ₂ (PW ₉ O ₃₄ ) ₂ .nH ₂ O " 50 K ₁₀ Mn ₄ (H ₂ O) ₂ (PWgO ₃₄ ) ₂ .nH ₂ O " 51 K ₁₀ Fe ₄ (H ₂ O) ₂ (PW ₉ O ₃₄ ) ₂ .nH ₂ O " 52 K ₁₂ Cu ₃ (PW ₉ O ₃₄ ) ₂ .nH ₂ O " 53 K ₁₂ (COH ₂ O) ₃ (PW ₉ O ₃₄ ) _2. nH ₂ O " 54 K ₁₂ Zn ₃ (PN ₉ O ₃₄ ) ₂ .15H ₂ O " 55 K ₁₂ Mn ₃ (PW ₉ O ₃₄ ) ₂ .5H ₂ O " 56 K ₁₂ Fe ₃ (PW ₉ O ₃₄ ) ₂ .25H ₂ O " 57 (ARGH ⁺ ) ₁₀ (NH ₄ ) ₇ Na [NaSb ₉ W ₂₁ O ₈₆ ] " 58 (ARGH ⁺ ) ₅ HW ₁₁ O ₃₉ .17H ₂ O " 59 K ₇ Ti ₂ W ₁₀ O ₄₀ " 60 [(CH ₃ ) ₄ N] ₇ Ti ₂ W ₁₀ O ₄₀ " 61 Cs ₇ Ti ₂ W ₁₀ O ₄₀ " 62 [HISH ⁺ ] ₇ Ti ₂ W ₁₀ O ₄₀ " 63 [LYSH ⁺ ] _n Na _7-n PTi ₂ W ₁₀ O ₄₀ " 64 [ARGH ⁺ ] _n Na _7-n PTi ₂ W ₁₀ O ₄₀ " 65 [n-Buty] ₄ N ⁺ ] ₃ H ₃ V ₁₀ O ₂₈ " 66 K ₇ HNb ₆ O ₁₉ .13H2O " 67 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O [SiCH ₂ CH ₂ C (O) OCH ₃ ] ₂ Organically modified structure 68 [(CH ₃ ) ₄ N ⁺ ] ₄ PW ₁₁ O ₃₉ - (SiCH ₂ CH ₂ CH ₂ CN) " 69 [(CH ₃ ) ₄ N ⁺ ] ₄ PW ₁₁ O ₃₉ - (SiCH ₂ CH ₂ CH ₂ Cl) " 70 [(CH ₃ ) ₄ N ⁺ ] ₄ PW ₁₁ O ₃₉ - (SiCH ₂ = CH ₂ ) " 71 CS ₄ [SiW11O ₃₉ - (SiCH ₂ CH ₂ C (O) OCH ₃ ) ₂ ] ₄ " 72 Cs ₄ [SiW11O ₃₉ - (SiCH ₂ CH ₂ CH ₂ CN)] ₄ " 73 Cs ₄ [SiW11O ₃₉ - (CH ₂ CH ₂ CH ₂ C)) _{2] 4} " 74 Cs ₄ [SiW11O ₃₉ - (SiCH ₂ = CH ₂ )] ₄ " 75 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O- (SiCH ₂ CH ₂ CH ₂ Cl) ₂ " 76 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O (SiCH ₂ CH ₂ CH ₂ CN) ₂ " 77 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O (SiCH ₂ = CH ₂ ) ₂ " 78 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O [SiC (CH ₃ )] ₂ " 79 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O [SiCH ₂ CH (CH ₃ )] ₂ " 80 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O [SiCH ₂ CH ₂ C (O) OCH ₃ ] ₂ " 81 K ₅ Mn (II) PW ₁₁ O ₃₉ .nH ₂ O Transition-metal-substituted structure 82 K ₈ Mn (II) P ₂ W ₁₇ O ₆₁ .nH ₂ O " 83 K ₆ Mn (II) SiW ₁₁ O ₃₉ .nH ₂ O " 84 K ₅ PW ₁₁ O ₃₉ [Si (CH ₃ ) ₂ ] .nH ₂ O " 85 K ₃ PW ₁₁ O ₄₁ (PC ₆ H ₅ ) ₂ .nH ₂ O " 86 Na ₃ PW ₁₁ O ₄₁ (PC ₆ H ₅ ) ₂ .nH ₂ O " 87 K ₅ PTiW ₁₁ O ₄₀ " 88 Cs ₅ PTiW ₁₁ O ₃₉ " 89 K ₆ SiW ₁₁ O ₃₉ [Si (CH ₃ ) ₂ ] .nH ₂ O " 90 KSiW ₁₁ O ₃₉ [Si (C ₆ H ₅ ) (tert-C ₄ H ₉ )]. NH ₂ O " 91 K ₆ SiW ₁₁ O ₃₉ [Si (C ₆ H ₅ ) ₂ ] .nH ₂ O " 92 K ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O " 93 Cs ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O " 94 Cs ₈ Si ₂ W ₁₈ Nb ₆ O ₇₇ .nH ₂ O " 95 [(CH ₃ ) ₃ NH ⁺ ] ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O Substituted Keggin structure 96 (CN ₃ H ₆ ) ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O " 97 (CN ₃ H ₆ ) ₈ Si ₂ W ₁₈ Nb ₆ O ₇₇ .nH ₂ O " 98 Rb ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O " 99 Rb ₈ Si ₂ W ₁₈ Nb ₆ O ₇₇ .nH ₂ O " 100 K ₈ Si ₂ W ₁₈ Nb ₆ O ₇₇ .nH ₂ O " 101 K ₆ P ₂ Mo ₁₈ O ₆₂ .nH ₂ O " 102 (C ₅ H ₅ N) ₇ HSi ₂ W ₁₈ Nb ₆ O ₇₇ .nH ₂ O " 103 (C ₅ H ₅ N) ₇ SiW ₉ Nb ₃ O ₄₀ .nH ₂ O " 104 (ARGH ⁺ ) ₈ SiW ₁₈ Nb ₆ O ₇₇ .18H ₂ O " 105 (LYSH ⁺ ) ₇ KSiW ₁₈ Nb ₆ O ₇₇ .18H ₂ O " 106 (HISH ⁺ ) ₆ K ₂ SiW ₁₈ Nb ₆ O ₇₇ .18H ₂ O " 107 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O (SiCH ₂ CH ₃ ) ₂ " 108 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O (SiCH ₃ ) ₂ " 109 [(CH ₃ ) ₄ N ⁺ ] ₄ SiW ₁₁ O ₃₉ -O (SiC ₁₆ H ₃₃ ) ₂ " 110 Li ₉ P ₂ V ₃ (CH ₃ ) ₃ W ₁₂ O ₆₂ " 111 Li ₇ HSi ₂ W _i8 Nb ₆ O ₇₇ " 112 Cs ₉ P ₂ V ₃ CH ₃ W ₁₂ O ₆₂ " 113 Cs ₁₂ P ₂ V ₃ W ₁₂ O ₆₂ " 114 K ₄ H ₂ PV ₄ W ₈ O ₄₀ " 115 Na ₁₂ P ₄ W ₁₄ O ₅₈ " 116 Na ₁₄ H ₆ P ₆ W ₁₈ O ₇₉ " 117 aK ₅ (NbO ₂ ) SiW ₁₁ O ₃₉ " 118 aO ₂ ) SiW ₁₁ O ₃₉ " 119 [(CH ₃ ) ₃ NH ⁺ ) ₅ NbSiW ₁₁ O ₄₀ " 120 [(CH ₃ ) ₃ NH ⁺ ] ₅ TaSiW ₁₁ O ₄₀ " 121 K ₆ Nb ₃ PW ₉ O ₄₀ Peroxo Keggin structure 122 [(CH ₃ ) ₃ NH ⁺ ] ₅ (NbO ₂ ) SiW ₁₁ O ₃₉ " 123 [(CH ₃ ) ₃ NH ⁺ ] ₅ (TaO ₂ ) SiW ₁₁ O ₃₉ " 124 K ₄ (NbO ₂ ) PW ₁₁ O ₃₉ " 125 K ₇ (NbO ₂ ) P ₂ W ₁₂ O ₆₁ " 126 [(CH ₃ ) ₃ NH ⁺ ] ₇ (NbO ₂ ) ₃ SiW ₉ O ₃₇ " 127 Cs ₇ (NbO ₂ ) ₃ SiW ₉ O ₃₇ " 128 K ₆ (NbO ₂ ) ₃ PW ₉ O ₃₇ " 129 Na ₁₀ (H ₂ W ₁₂ O ₄₂ ) " 130 K ₄ NbPW ₁₁ O ₄₀ " 131 [(CH ₃ ) ₃ NH ₊ ] ₄ NbPW ₁₁ O ₄₀ " 132 K ₅ NbSiW ₁₁ O ₄₀ " 133 K ₅ TaSiW ₁₁ O ₄₀ " 134 K ₇ NbP ₂ W ₁₇ O ₆₂ Wells-Dawson structure 135 K ₇ (TiO ₂ ) ₂ PW ₁₀ O ₃₈ " 136 K ₇ (TaO ₂ ) ₃ SiW ₉ O ₃₇ " 137 K ₇ Ta ₃ SiW ₉ O ₄₀ " 138 K ₆ (TaO ₂ ) ₃ PW ₉ O ₃₇ " 139 K ₆ Ta ₃ PW ₉ O ₄₀ " 140 K ₈ CO ₂ W ₁₁ O ₃₉ " 141 H ₂ [(CH ₃ ) ₄ N ⁺ ] 4 (C ₂ H ₅ Si) ₂ CoW ₁₁ O ₄₀ " 142 H ₂ [(CH ₃ ) ₄ N ⁺ ] ₄ (iso-C ₄ H ₉ Si) ₂ CoW ₁₁ O ₄₀ " 143 K ₉ Nb ₃ P ₂ W ₁₅ O ₆₂ " 144 K ₉ (NbO ₂ ) ₃ P ₂ W ₁₅ O ₅₉ " 145 K ₁₂ (NbO ₂ ) ₆ P ₂ W ₁₂ O ₅₆ Well-Dawson peroxo 146 K ₁₂ Nb ₆ P ₂ W ₁₂ O ₆₂ Wells-Dawson structure ff. 147 a ₂ -K ₁₀ P ₂ W ₁₇ O ₆₁ " 148 K ₆ Fe (III) Nb ₃ P ₂ W ₁₅ O ₆₂ " 149 K ₇ Zn (II) Nb ₃ P ₂ W ₁₅ O ₆₂ " 150 (NH ₄ ) ₆ (aP ₂ W ₁₈ O ₆₂ ) .nH ₂ O " 151 K ₁₂ [H ₂ P ₂ W ₁₂ O ₄₈ ] .24H ₂ O " 152 K ₂ Na ₁₅ H ₅ [PtMo ₆ O ₂₄ ] .8H ₂ O " 153 K ₈ [a ₂ -P ₂ W ₁₇ MoO ₆₂ ] .nH ₂ O " 154 KHP ₂ V ₃ W ₁₅ O ₆₂ .34H ₂ O " 155 K ₆ [P ₂ W ₁₂ Nb ₆ O ₆₂ ] .24H ₂ O " 156 Na ₆ [V ₁₀ O ₂₈ ] .H ₂ O " 157 (Guanidinium) ₈ H [PV ₁₄ O ₆₂ ] .3H ₂ O " 158 K8H [PV14O62] " 159 Na ₇ [MnV ₁₃ O ₃₈ ] .18H ₂ O " 160 K ₆ [BW ₁₁ O ₃₉ Ga (OH) ₂ ] .13H ₂ O " 161 K ₇ H [Nb ₆ O ₁₉ ] .13H ₂ O " 162 [(CH ₃ ) ₄ N ⁺ / Na ⁺ / K ⁺ ] ₄ [Nb ₂ W ₄ O ₁₉ ] " 163 [(CH ₃ ) ₄ N ⁺ ] ₉ [P ₂ W ₁₅ Nb ₃ O ₆₂ ] " 164 [(CH ₃ ) ₄ N ⁺ ] ₁₅ [HP ₄ W ₃₀ Nb ₆ O ₁₂₃ ] .16H ₂ O " 165 [Na / K] ₆ [Nb ₄ W ₂ O ₁₉ ] " 166 [(CH _{3) 4} N ⁺ / Na ⁺ / K ^+] 5 _[Nb3W3O19] .6H ₂ O " 167 K ₅ [CpTiSiW ₁₁ O ₃₉ ] .12H ₂ O " 169 b ₂ -K ₈ [SiW ₁₁ O ₃₉ ] .14H ₂ O " 170 aK ₈ [SiW ₁₀ O ₃₆ ] .12H ₂ O " 171 Cs ₇ Na ₂ [PW ₁₀ O ₃₇ ] .8H ₂ O " 172 Cs ₆ [P ₂ W ₅ O ₂₃ ] .7.5H ₂ O " 173 g-Cs ₇ [PW ₁₀ O ₃₆ ] .7H ₂ O " 174 K ₅ [SiNbW ₁₁ O ₄₀ ] .7H ₂ O " 175 K ₄ [PNbW ₁₁ O ₄₀ ] .12H ₂ O " 176 Na ₆ [Nb ₄ W ₂ O ₁₉ ] .13H ₂ O " 177 K ₆ [Nb ₄ W ₂ O ₁₉ ] .7H ₂ O " 180 K ₄ [V ₂ W ₄ O ₁₉ ] .3.5H ₂ O " 181 Na ₅ [V ₃ W ₃ O ₁₉ ] .12H ₂ O " 182 K ₆ [PV ₃ W ₉ O ₄₀ ] .14H ₂ O " 183 Na ₉ [Ab-GeW ₉ O ₃₄ ] .8H ₂ O " 184 Na ₁₀ [Aa-GeW ₉ O ₃₄ ] .9H ₂ O " 185 K ₇ [BV ₂ W ₁₀ O ₄₀ ] .6H ₂ O " 186 Na ₅ [CH ₃ Sn (Nb ₆ O ₁₉ )]. 10H ₂ O " 187 Na ₈ [Pt (P (m-SO ₃ C ₆ H ₅ ) ₃ ) ₃ Cl] .3H ₂ O " 188 [(CH ₃ ) ₃ NH ⁺ ] ₁₀ (H) [Si (H) ₃ W ₁₈ O ₆₈ ] .10H ₂ O " 189 K ₇ [Aa-GeNb ₃ W ₉ O ₄₀ ] .18H ₂ O " 190 K ₇ [Ab-SiNb ₃ W ₉ O ₄₀ ]. 20H ₂ O " 191 [(CH ₃ ) ₃ NH ⁺ ] ₉ [Aa-HGe ₂ Nb ₆ W ₁₈ O ₇₈ " 192 K ₇ (H) [Aa-Ge ₂ Nb ₆ W ₁₈ O ₇₇ ] .18H ₂ O " 193 K ₈ [Ab-Si ₂ Nb ₆ W ₁₈ O ₇₇ ] " 194 [(CH ₃ ) ₃ NH ⁺ ] ₈ [AB-Si ₂ Nb ₆ W ₁₈ O ₇₇ ] "

• a) cf. US 6,020,369 , TABLE 1, columns 3 to 10;
• b) Tierui Zhang, Shaoquin Liu, Dirk G. Kurth and Charl FJ Faul, Organized Nanostructured Complexes of Polyoxometalates and Surfactants that Exhibit Photoluminescence and Electrochromism, Advanced Functional Materials, 2009, 19, 642-652 ;
• n number, in particular integer, from 1 to 50.

Further examples of suitable POM are from the American patent US Pat. No. 7,097,858 B2 , Column 14, line 56, to column 17, line 19, and from TABLE 8a, column 22, line 41, to column 23, line 28, compounds number 1-53, and TABLE 8b, column 23, line 30, to column 25, line 34, compounds number 1 to 150, known.

• - Ammoniumheptamolybdat-Tetrahydrat {(NH₄)₆Mo₇O₂₄] · 4H₂O, CAS-Nr.13106-76-8 (wasserfrei), CAS-Nr. 12054-85-2 (Tetrahydrat), AHMT},
• - Wolframatophosphorsäure-Hydrat {H₃[P(W₃O₁₀)₄] · xH₂O, CAS-Nr. 1343-93-7 (wasserfrei), CAS-Nr. 12067-99-1 (Hydrat), Wo-Pho},
• - Molybdatophosphorsäure-Hydrat, {H₃P(Mo₃O₁₀)4] · xH₂O, CAS-Nr.:12026-57-2 (wasserfrei), CAS-Nr. 51429-74-4 (Hydrat), Mo-Pho} und/oder
• - Wolframatokieselsäure {H₄[Si(W₃O₁₀)₄] · xH₂O, CAS-Nr. 12027-43-9, CAS-Nr. WKS}

und/oder ihre Salze verwendet.Very particularly preferred

• - Ammonium heptamolybdate tetrahydrate {(NH ₄ ) ₆ Mo ₇ O ₂₄ ] · 4H ₂ O, CAS No.13106-76-8 (anhydrous), CAS-No. 12054-85-2 (tetrahydrate), AHMT},
• Tungstophosphoric hydrate {H ₃ [P (W ₃ O ₁₀ ) ₄ ] .xH ₂ O, CAS-No. 1343-93-7 (anhydrous), CAS no. 12067-99-1 (hydrate), Wo-Pho},
• - Molybdatophosphoric acid hydrate, {H ₃ P (Mo ₃ O ₁₀ ) 4] xH ₂ O, CAS No: 1206-57-2 (anhydrous), CAS-No. 51429-74-4 (hydrate), Mo-Pho} and / or
• Tungstosilicic acid {H ₄ [Si (W ₃ O ₁₀ ) ₄ ] .xH ₂ O, CAS no. 12027-43-9, CAS no. WKS}

and / or their salts.

The molecular POMs to be used according to the invention can be prepared by means of customary and known wet-chemical processes, such as, for example, precipitation processes.

The POM microparticles and POM nanoparticles to be used according to the invention can be prepared by customary and known wet-chemical processes. However, it is also possible to dissolve the POM in water and to spray the resulting solution against a warm stream of air. In addition, it is possible to evaporate the solution under vacuum, being irradiated with IR radiation. Furthermore, it is possible to prepare solutions, in particular aqueous, solutions of POM on cold surfaces, such as frozen, smooth metal surfaces, dry ice, cryogenic organic solvents and liquefied gases, such as methane, ethane propane, butane, methylcyclohexane or benzine, liquid nitrogen or liquid helium spray on and evaporate the dry ice or the liquid substances.

The molecular POM, POM microparticles and / or POM nanoparticles described above are unchanged, oxygen-substituted, functionalized, aggregated, agglomerated and / or supported. For example, they may be functionalized, agglomerated and supported. But they can also not be functionalized and not aggregated.

They may be dissolved, suspended, lipophilized and / or fluidized with organic groups and / or in and / or on compact and / or porous as acid, salt, soft oxometalate (SOMS), coating and / or polyoxometalate nanocomposite and / or molecular disperse Particles, films, fibers and / or sponges, in hydrogels, in micelles, in vesicles, in microcapsules, in gels, in powders, in and on coatings, in and on plastics, in and on tablets, in creams, lotions, ointments and / or foams and / or in mixtures and / or in conjunction with functional materials, antibiotics and / or biocidal materials.

In addition, they may be present in the POM preparations as disclosed in the documents described above.

The unaltered POMs are the POMs that arise during their manufacture without further functionalization or modification.

In the oxygen-displaced POM, terminal oxide centers are replaced by other ligands, such as sulfide ions, bromide ions, amino groups, nitrosyl groups, and / or alkoxy groups. The sulfur-containing POM are also called polyoxothiometalates.

The aggregates are loose aggregates of particles that are held together by cohesion and can not be distributed by conventional and known dispersion methods. Their inner surface is smaller than the sum of the surfaces of the primary particles.

The agglomerates are aggregates of primary particles and their aggregates, which are bridged over edges and corners. Their inner surface corresponds approximately to the sum of the surfaces of the primary particles.

The molecular POM, POM microparticles and POM nanoparticles to be used according to the invention can be present "naked". That is, their surface is not surrounded by a shell and / or is not functionalized.

Furthermore, the molecular POM, POM microparticles and POM nanoparticles to be used according to the invention can be surrounded by a shell and / or carry at least one functional group. In this case, the material of the shells may carry the functional groups or else the functional groups may be present directly on the surface of the molecular POM, the POM microparticles and the POM nanoparticles.

The material of the shell and / or the functional groups can be selected so that the molecular POM, POM microparticles and POM nanoparticles to be used according to the invention are particularly rapidly and homogeneously in an organic and / or inorganic, solid or liquid matrix, in particular a distribute and / or modify the physical and / or chemical properties of the molecular POM, POM microparticles, and POM nanoparticles in a particular desired manner, and / or modify the physical and / or chemical properties of the organic and / or inorganic polymeric matrix or inorganic ceramic matrix acting as a support material and / or binder mask.

The shells and / or the functional groups may be attached to the surface of the molecular POM, POM microparticles and POM nanoparticles via covalent and / or ionic bonds and / or electrostatic and / or van der Waals forces.

The bond between the surface of the molecular POM, POM microparticles and POM nanoparticles and the shell and / or the functional groups can be permanently or reversibly, i. be solvable again.

The shells may be constructed of organic, inorganic and organometallic, polymeric, oligomeric and low molecular weight materials or combinations of at least two of these materials.

For further details, see the international patent application WO 2016/116259 A1 , Page 25, line 11, to page 38, page 32, referenced.

In addition, the topical preparations according to the invention may contain at least one ingredient (E) commonly used for topical preparations, selected from the group consisting of water, phyllosilicates, ground clays, Bolus Americus clays, healing earth, nut shells, willow bark, Lapacho crayfish, siliceous earth, pumice stone, geopolymers, amber, precious stones, trace elements and neutral inorganic salts, beta-glucans, glutathione, albumin, xylan, phytates, complexing agents, antioxidants, radical scavengers, menthol, caffeine, teein, papain, esculin hemihydrate, carotenoids, Lecithins, abscinoic acid, cyanidin, guanidine, urea, thiourea, fillers, solvents, humectants, solubilizers, nonionic wetting agents, buffers, thickeners, binders, wraps, disintegrants, disintegrants, lubricants, lubricants, mold release agents, flow control agents, antioxidants, preservatives, sweeteners, flavoring agents Absorption enhancers, alkalizing agents, acidulants, neutralizing agents, foam inhibitors and defoamers, dyes, color pigments, oxidizing agents, reducing agents, stabilizers, propellants, opacifiers, pearlescers , Denaturants, emollients, minerals, vitamins, micelles, superabsorbents, moisturizers, oils, fragrances, flavors, perfumes, moisturizers, moisturizers, skin care ingredients, deodorizing agents, film formers, gelling agents, tannins, tanning agents, tannin extracts, bittering agents, plant extracts, Honeys, colostrum, cytostatics, antibodies, immunoglobulins, essential and non-essential amino acids and fats, hyaluronic acid, aloe vera gel, alkylene glycols, polyalkylene ether glycols, proteins, peptides, carbohydrates, lipids, nucleic acids, nucleic acid fragments, antiviral compounds, antiinflammatory compounds, antibiotics, cell differentiation reagents, Analgesics, narcotics, anesthetics, contrast agents, enzymes, cytokines, antihistamines, immunomodulators, hemostatic agents, hormones, angiogenic and antiangiogenic agents, neurotransmitters, therapeutic oligo nucleotides, viral particles, growth factors, retinoids, cell adhesion factors, extracellular matrix glycoproteins, osteogenic factors, antibodies, antigens, steroids, analgesics, potassium sulfate, royal jelly, propolis, encapsulated fragrances, nutrients hexahydroxycyclohexanehexaphosphoric acid ester salt nanoparticles, especially salts of phytic acid, and surfactants Contain quantities.

Examples of suitable ingredients are, in particular, phyllosilicates which are preferably nanoparticles and / or microparticles having an average particle size d _{50 of} from 1 nm to <1000 μm, preferably from 10 nm to 900 μm, preferably from 300 nm to 1000 nm, particularly preferably 650 ± 200 nm particularly preferably 650 ± 150 nm and in particular 650 ± 100 nm are present

• - Inselsilikate
• - Gruppensilikate
• - Ringsilikate
• - Ketten- und Bandsilikate
• - Übergangsstrukturen zwischen Ketten- und Schichtsilikaten
• - Schichtsilikate
• - Gerüstsilikate

The elemental composition and the structure of the layered silicate micro- and / or nanoparticles can also vary widely. For example, the classification of the silicates into the following structures is known:

• - island silicates
• - group silicates
• - Ring silicates
• - Chain and tape silicates
• - Transition structures between chain and layer silicates
• - phyllosilicates
• - Framework silicates

Phyllosilicates are silicates whose silicates consist of layers of corner-sharing SiO ₄ tetrahedra. These layers and / or bilayers are not further linked to one another. The technically important and in sedimentary rocks widespread clay minerals are also phyllosilicates. The layered structure of these minerals determines the shape and properties of the crystals. They are usually tabular to leafy with good to perfect cleavage parallel to the layers. The number of rings that make up the silicate layers often determines the symmetry and shape of the crystals. Between the layers, water molecules, large cations and / or lipids can be stored.

1. a) vgl. Mineralienatlas, Mineralklasse VIII/H - Schichtsilikate (Phyllosilikate), Strunz 8 Systematik

Examples of suitable sheet silicates are shown in Table 2 below. The list is exemplary and not exhaustive. Table 2: Sum formulas of suitable phyllosilicates ^a) No. Type Molecular formula 1 Martinit (Na, Ca) ₁₁ Ca ₄ (Si, S, B) ₁₄ B ₂ O ₄₀ F ₂ .4 (H ₂ O) 2 Apophyllit- (NaF) NaCa ₄ Si ₈ O ₂₀ F · 8H ₂ O 3 Apophyllit- (KF) (K, Na) Ca ₄ Si ₈ O ₂₀ (F, OH) .8H ₂ O 4 Apophyllit- (KOH) KCa ₄ Si ₈ O ₂₀ (OH, F) · 8H ₂ O 5 Cuprorivait CaCuSi ₄ O ₁₀ 6 Wesselsit (Sr, Ba) Cu [Si ₄ O ₁₀ ] 7 Effenbergerit BaCu [Si ₄ O ₁₀ ] 8th gillespite BaFe ²⁺ Si ₄ O ₁₀ 9 sanbornite BaSi ₂ O ₅ 10 Bigcreekit BaSi ₂ O ₅ · 4H ₂ O 11 Davanit K ₂ TiSi ₆ O ₁₅ 12 Dalyit K ₂ ZrSi ₆ O ₁₅ 13 Fenaksit KNaFe ²⁺ Si ₄ O ₁₀ 14 Manaksit KNaMn ²⁺ [Si ₄ O ₁₀ ] 15 Ershovit K ₃ Na ₄ (Fe, Mn, Ti) ₂ [Si ₈ O ₂₀ (OH) ₄ ] .4H ₂ O 16 Paraershovit Na ₃ K ₃ Fe ₃ ⁺ ₂ Si ₈ O ₂₀ (OH) ₄ .4H ₂ O 17 natrosilite Na ₂ Si ₂ O ₅ 18 kanemite NaSi ₂ O ₅ .3H ₂ O 19 revdite Na ₁₆ Si ₁₆ O ₂₇ (OH) _26. 28H ₂ O 20 Latiumit (Ca, K) ₄ (Si, Al) ₅ O ₁₁ (SO ₄ , CO ₃ ) 21 Tuscanite K (Ca, Na) ₆ (Si, Al) ₁₀ O ₂₂ (SO ₄ , CO ₃ , (OH) ₂ ) .H ₂ O 22 Carletonit KNa ₄ Ca ₄ Si ₈ O ₁₈ (CO ₃ ) ₄ (OH, F) H ₂ O 23 pyrophyllite Al ₂ Si ₄ O ₁₀ (OH) ₂ 24 Ferripyrophyllit Fe ³⁺ Si ₂ O ₅ (OH) 25 Macaulayit (Fe ³⁺ , Al) ₂₄ Si ₄ O ₄₃ (OH) ₂ 26 talc Mg ₃ Si ₄ O ₁₀ (OH) ₂ 27 Minnesotait Fe ²⁺ ₃ Si ₄ O ₁₀ (OH) ₂ 28 Willemseite (Ni, Mg) ₃ Si ₄ O ₁₀ (OH) ₂ 29 Pimelit Ni ₃ Si ₄ O ₁₀ (OH) ₂ .4H ₂ 0 30 Kegelit Pb ₄ Al ₂ Si ₄ O ₁₀ (SO ₄ ) (CO ₃ ) ₂ (OH) ₄ 31 Aluminoseladonit K (Mg, Fe ²⁺ ) Al [(OH) ₂ | Si ₄ O ₁₀ ] 32 Ferroaluminoseladonit K (Fe ²⁺ , Mg) (Al, Fe ³⁺ ) [(OH) ₂ | Si ₄ O ₁₀ ] 33 seladonite K (Mg, Fe ²⁺ ) (Fe ³⁺ , Al) Si ₄ O ₁₀ (OH) ₂ 34 Chromseladonit KMgCr [(OH) ₂ | Si ₄ O ₁₀ ] 35 Ferroseladonit K (Fe ²⁺ Mg) (Fe + ^3, Al) [(OH) ₂ | Si ₄ O ₁₀ | 36 paragonite NaAl ₂ (Si ₃ Al) O ₁₀ (OH) ₂ 37 Boromuskovit KAl ₂ (Si ₃ B) O ₁₀ (OH, F) ₂ 38 mica KAl ₂ (Si ₃ Al) O ₁₀ (OH, F) ₂ 39 Chrome phyllite K (Cr, Al) ₂ [(OH, F) ₂ | AlSi ₃ O ₁₀ ] 40 roscoelite K (V, Al, Mg) ₂ AlSi ₃ O ₁₀ (OH) ₂ 41 Ganterit (Ba, Na, K) (Al, Mg) ₂ [(OH, F) ₂ | (Al, Si) Si ₂ O 10] 42 Tobelith (NH ₄ , K) A) ₂ (Si ₃ A)) O ₁₀ (OH) ₂ 43 Nanpingit CsAl ₂ (Si, Al) ₄ O ₁₀ (OH, F) ₂ 44 Polylithionit KLi ₂ AlSi ₄ O ₁₀ (F, OH) ₂ 45 Tainiolith KLiMg ₂ Si ₄ O ₁₀ F ₂ 46 Norrishit KLiMn ³⁺ ₂ Si ₄ O ₁₂ 47 Shirokshinit CNaMg ₂ [F ₂ | Si ₄ O ₁₀ ] 48 Montdorit KMn _0.5 ²⁺ Fe _1.5 ²⁺ Mg _0.5 [F ₂ | Si ₄ O ₁₀ ] 49 Trilithionite KLi _1.5 Al _1.5 [F ₂ | AlSi ₃ O ₁₀ ] 50 Masutomilith K (Li, Al, Mn ²⁺ ) ₃ (Si, Al) ₄ O ₁₀ (F, OH) ₂ 51 Aspidolite-1 M NaMg ₃ (AlSi ₃ ) O ₁₀ (OH) ₂ 52 fluorophlogopite KMg ₃ (AlSi ₃ ) O ₁₀ F ₂ 53 phlogopite KMg ₃ (Si ₃ Al) O ₁₀ (F, OH) ₂ 54 Tetraferriphlogopit KMg ₃ [(F, OH) ₂ ] (Al, Fe ³⁺ ) Si ₃ O ₁₀ ] 55 Hendricksit K (Zn, Mn) ₃ Si ₃ AlO ₁₀ (OH) ₂ 56 Shirozulith K (Mn ²⁺ , Mg) ₃ [(OH) ₂ | AlSi ₃ O ₁₀ ] 57 Fluorannit Kfe ₃ ²⁺ [(F, OH) ₂ | AlSi ₃ O ₁₀ ] 58 Annite Kfe ²⁺ ₃ (Si ₃ Al) O ₁₀ (OH, F) ₂ 59 Tetraferriannit K Fe ²⁺ ₃ (Si ₃ Fe ³⁺ ) O ₁₀ (OH) ₂ 60 Ephesit NaLiAl ₂ (Al ₂ Si ₂ ) O ₁₀ (OH) ₂ 61 Preiswerkite NaMg ₂ Al ₃ Si ₂ O ₁₀ (OH) ₂ 62 Eastonit KMg ₂ Al [(OH) ₂ | Al ₂ Si ₂ O ₁₀ ] 63 Siderophyllit Kfe ₂ ²⁺ Al (Al ₂ Si ₂ ) O ₁₀ (F, OH) ₂ 64 Anandit (Ba, K) (Fe ²⁺ , Mg) ₃ (Si, Al, Fe) ₄ O ₁₀ (S, OH) ₂ 65 Bityit CaLiAl ₂ (AlBeSi ₂ ) O ₁₀ (OH) ₂ 66 Oxykinoshitalith (Ba, K) (Mg, Fe ²⁺ Ti ⁴⁺ ) ₃ (Si Al) ₄ O ₁₀ O ₂ 67 Kinoshitalith (Ba, K) (Mg, Mn, Al) ₃ Si ₂ Al ₂ O ₁₀ (OH) ₂ 68 Ferrokinoshitalith Ba (Fe ²⁺ , Mg) ₃ [(OH, F) ₂ | Al ₂ Si ₂ O ₁₀ ] 69 Margarit CaAl ₂ (Al ₂ Si ₂ ) O ₁₀ (OH) ₂ 70 Chernykhit BaV ₂ (Si ₂ Al ₂ ) O ₁₀ (OH) ₂ 71 clintonite Ca (Mg, Al) ₃ (Al ₃ Si) O ₁₀ (OH) ₂ 72 Wonesit (Na, K,) (Mg, Fe, Al) ₆ (Si, Al) ₈ O ₂₀ (OH, F) ₄ 73 brammallite (Na, H ₃ O) (Al, Mg, Fe) ₂ (Si, Al) ₄ O ₁₀ [(OH) ₂ , H ₂ O] 74 Illit (K, H ₃ O) Al ₂ (Si ₃ Al) O ₁₀ (H ₂ O, OH) ₂ 75 glauconite (K, Na) (Fe ³⁺ , Al, Mg) ₂ (Si, Al) ₄ O ₁₀ (OH) ₂ 76 agrellite NaCa ₂ Si ₄ O ₁₀ F 77 Glagolevit NaMg ₆ [(OH, O) ₈ | AlSi ₃ O ₁₀ ] H ₂ O 78 Erlianit Fe ²⁺ ₄ Fe ³⁺ ₂ Si ₆ O ₁₅ (OH) ₈ 79 Bannisterit (Ca, K, Na) (Mn ²⁺ , Fe ²⁺ , Mg, Zn) ₁₀ (Si, Al) ₁₆ O ₃₈ (OH) ₈ · nH ₂ O. 80 Bariumbannisterit (K, H ₃ O) (Ba, Ca) (Mn ²⁺ , Fe ²⁺ , Mg) ₂₁ (Si, Al) ₃₂ O ₈₀ (O, OH) ₁₆ x 4-12 H ₂ O. 81 Lennilenapeit K _6-7 (Mg, Mn, Fe ²⁺ , Fe ³⁺ , Zn) ₄₈ (Si, Al) ₇₂ (O, OH) ₂₁₆ · 16H ₂ O. 82 stilpnomelane K (Fe ²⁺ , Mg, Fe ³⁺ , Al) ₈ (Si, Al) ₁₂ (O, OH) ₂₇ · 2H ₂ O. 83 Franklinphilit (K, Na) _1-x (Mn ²⁺ , Mg, Zn, Fe ³⁺ ) ₈ (Si, Al) ₁₂ (O, OH) ₃₆ · H ₂ O. 84 Parsettensite (K, Na, Ca) _7.5 (Mn, Mg) ₄₉ Si ₇₂ O ₁₆₈ (OH) ₅₀ .H ₂ O 85 Middendorfit K ₃ Na ₂ Mn ₅ Si ₁₂ (O, OH) ₃₆ · 2H ₂ O 86 Eggletonit (Na, K, Ca) ₂ (Mn, Fe) ₈ (Si, Al) ₁₂ O ₂₉ (OH) ₇ · 11H ₂ O 87 Ganophyllit (K, Na) _× Mn ²⁺ ₆ (Si, Al) ₁₀ O ₂₄ (OH) ₄ · nH ₂ O {x = 1-2} {n = 7-11} 88 Tamait (Ca, K, Ba, Na) _3-4 Mn ²⁺ ₂₄ [(OH) ₁₂ | {(Si, Al) ₄ (O, OH) ₁₀ } ₁₀ ] · 21H ₂ O 89 Ekmanit (Fe ²⁺ , Mg, Mn, Fe ³⁺ ) ₃ (Si, Al) ₄ O ₁₀ (OH) ₂ .2H ₂ O. 90 Lunijianlait Li _0.7 Al _6.2 (Si ₇ AlO ₂₀₎ (OH, O) ₁₀ 91 Saliotit Na _0.5 Li _0.5 Al ₃ [(OH) ₅ | AlSi ₃ O ₁₀ ] 92 Kulkeit Na _0.35 Mg ₈ Al (AlSi ₇ ) O ₂₀ (OH) ₁₀ 93 Aliettit Ca _0.2 Mg ₆ (Si, Al) ₈ O ₂₀ (OH) ₄ .4H ₂ O 94 rectorite (Na, Ca) Al ₄ (Si, Al) ₃ O ₂₀ (OH) ₄ .2H ₂ O 95 tarasovite (Na, K, H ₃ O, Ca) ₂ Al ₄ [(OH) ₂ ] (Si, Al) ₄ O ₁₀ ] ₂ .H ₂ O 96 tosudite Na _0.5 (Al, Mg) ₆ (Si, Al) ₈ O ₁₈ (OH) ₁₂ .5H ₂ O 97 corrensite (Ca, Na, K) (Mg, Fe, Al) ₉ (Si, Al) ₈ O ₂₀ (OH) ₁₀ .nH ₂ O 98 Brinrobertsit (Na, K, Ca) _0.3 (A), Fe, Mg) ₄ (Si, At) ₈ O ₂₀ (OH) _4. 3.5H ₂ O 99 montmorillonite (Na, Ca) _0.3 (Al, Mg) ₂ Si ₄ O ₁₀ (OH) ₂ .nH ₂ O 100 beidellite (Na, Ca _0.5 ) _0.3 Al ₂ (Si, Al) ₄ O ₁₀ (OH) ₂ .4H ₂ O 101 nontronite Na _0.3 Fe ₂ 3+ (Si, Al) ₄ O ₁₀ (OH) ₂ .4H ₂ O. 102 volkonskoite Ca _0.3 (Cr ³⁺ , Mg, Fe ³⁺ ) ₂ (Si, Al) ₄ O ₁₀ (OH) ₂ .4H ₂ O. 103 Swinefordite (Ca, Na) _0.3 (Al, Li, Mg) ₂ (Si, Al) ₄ O ₁₀ (OH, F) ₂ · 2H ₂ O 104 Yakhontovit (Ca, Na, K) ₀ . ₃ (CuFe ²⁺ Mg) ₂ Si ₄ O ₁₀ (OH) ₂ .3H ₂ O 105 hectorite Na _0.3 (Mg, Li) ₃ Si ₄ O ₁₀ (F, OH) ₂ 106 saponite (Ca ₂ , Na) _0.3 (Mg, Fe ²⁺ ) ₃ (Si, Al) ₄ O ₁₀ (OH) ₂ .4H ₂ O. 107 Ferrosaponite Ca _0.3 (Fe ²⁺ , Mg, Fe ³⁺ ) ₃ [(OH) ₂ ] (Si, Al) Si ₃ O ₁₀ ) 4H ₂ O. 108 Spadait MgSiO ₂ (OH) ₂ H ₂ O 109 stevensite (Ca | ₂ ) _0.3 Mg ₃ Si ₄ O ₁₀ (OH) ₂ 110 sauconite Na _0.3 Zn ₃ (Si, Al) ₄ O ₁₀ (OH) ₂ .4H ₂ O 111 Zinksilit Zn ₃ Si ₄ O ₁₀ (OH) ₂ .4H ₂ O. 112 vermiculite Mg ₀₇ (Mg, Fe, Al) ₆ (Si, Al) ₈ O ₂₀ (OH) ₄ .8H ₂ O 113 Rilandit (Cr ³⁺ , Al) ₆ SiO ₁₁ .5H ₂ O. 114 donbassite Al _2.3 [(OH) ₈ | AlSi ₃ O ₁₀ ] 115 sudoite Mg ₂ Al ₃ (Si ₃ Al) O ₁₀ (OH) ₈ 116 clinochlore (Mg, Fe ²⁺ ) ₅ Al (Si ₃ Al) O ₁₀ (OH) ₈ 117 chamosite (Fe ²⁺ , Mg, Fe ³⁺ ) ₅ Al (Si ₃ Al) O ₁₀ (OH, O) ₈ 118 Orthochamosit (Fe ²⁺ , Mg, Fe ³⁺ ) ₅ Al (Si ₃ Al) O ₁₀ (OH, O) ₈ 119 Baileychlor (Zn, Fe ²⁺ , Al, Mg) ₆ (Si, Al) ₄ O ₁₀ (OH) ₈ 120 Pennantit Mn ²⁺ ₅ Al (Si ₃ Al) O ₁₀ (OH) ₈ 121 Nimit (Ni, Mg, Fe ²⁺ ) ₅ Al (Si ₃ Al) O ₁₀ (OH) ₈ 122 Gonyerit Mn ²⁺ ₅ Fe ³⁺ (Si ₃ Fe ³⁺ O ₁₀ ) (OH) ₈ 123 cookeite LiAl ₄ (Si ₃ Al) O ₁₀ (OH) ₈ 124 Borocookeit Li _1-1.5 Al _4-3.5 [(OH, F) ₈ | (B, Al) Si ₃ O ₁₀ ] 125 Manandonit Li ₂ Al _{4 [} (Si ₂ AlB) O ₁₀ ] (OH) ₈ 126 franklinfurnaceite Ca ₂ (Fe ³⁺ Al) Mn ³⁺ Mn ₃ ²⁺ Zn ₂ Si ₂ O ₁₀ (OH) ₈ 127 Chambermerit (Var.v. Klinochlor) Mg ₅ (Al, Cr) ₂ Si ₃ O ₁₀ (OH) ₈ 128 Niksergievit (Ba, Ca) ₂ Al ₃ [(OH) ₆ | CO ₃ | (Si, Al) ₄ O ₁₀ ] 0.2H ₂ O. 129 Surite Pb ₂ Ca (Al, Mg) ₂ (Si, Al) ₄ O ₁₀ (OH) ₂ (CO ₃ , OH) ₃ .0.5 H ₂ O 130 Ferrisurite (Pb, Ca) _2-3 (Fe ³⁺ , Al) ₂ [(OH, F) _2.5-3 | (CO ₃ ) _1.5-2 | Si ₄ O ₁₀ ] _{0.5H 2} O. 131 kaolinite Al ₂ Si ₂ O ₅ (OH) ₄ 132 dickite Al ₂ Si ₂ O ₅ (OH) ₄ 133 Halloysite 7 Å Al ₂ Si ₂ O ₅ (OH) ₄ 134 Sturtit Fe ³⁺ (Mn ²⁺ , Ca, Mg) Si ₄ O ₁₀ (OH) ₃ · 10H ₂ O. 135 Allophan Al ₂ O ₃ · (SiO ₂ ) _1.3-2 · (H ₂ O) _2.5-3 136 Imogolith Al ₂ SiO ₃ (OH) ₄ 137 Odinit (Fe ³⁺ , Mg, Al, Fe ²⁺ , Ti, Mn) _2.4 (Si _1.8 Al _0.2 ) O ₅ (OH) ₄ 138 hisingerite Fe ₂ ³⁺ Si ₂ O ₅ (OH) ₄ .2H ₂ O. 139 Neotokit (Mn, Fe ²⁺ ) SiO ₃ .H ₂ O 140 chrysotile Mg ₃ Si ₂ O ₅ (OH) ₄ 141 Klinochrysotil Mg ₃ Si ₂ O ₅ (OH) ₄ 142 Maufit (Mg, Ni) Al ₄ Si ₃ O ₁₃ .4H ₂ O 143 Orthochrysotil Mg ₃ Si ₂ O ₅ (OH) ₄ 144 Parachrysotil Mg ₃ Si ₂ O ₅ (OH) ₄ 145 Antigorit (Mg, Fe ²⁺ ) ₃ Si ₂ O ₅ (OH) ₄ 146 lizardite Mg ₃ Si ₂ O ₅ (OH) ₄ 147 Karyopilit Mn ²⁺ ₃ Si ₂ O ₅ (OH) ₄ 148 Greenalith (Fe ²⁺ , Fe ³⁺ ) _2-3 Si ₂ O ₅ (OH) ₄ 149 berthierine (Fe ^2+, Fe ^3+, Al) ₃ (Si, Al) ₂ O ₅ (OH) ₄ 150 fraipontite (Zn, Al) ₃ (Si, Al) ₂ O ₅ (OH) ₄ 151 Zinalsit Zn ₇ Al ₄ (SiO ₄ ) ₆ (OH) ₂ .9H ₂ O 152 Dozyit Mg ₇ (Al, Fe ³⁺ , Cr) ₂ [(OH) ₁₂ | Al ₂ Si ₄ O ₁₅ ] 153 Amesit Mg ₂ Al (SiAl) O ₅ (OH) ₄ 154 Kellyit (Mn ²⁺ , Mg, Al) ₃ (Si, Al) ₂ O5 (OH) ₄ 155 Cronstedtit Fe ₂ ²⁺ Fe ³⁺ (SiFe ³⁺ ) O ₅ (OH) ₄ 156 Karpinskit (Mg, Ni) ₂ Si ₂ O ₅ (OH) ₂ 157 népouite (Ni, Mg) ₃ Si ₂ O ₅ (OH) ₄ 158 Pecorait Ni ₃ Si ₂ O ₅ (OH) ₄ 159 Brindleyit (Ni, Mg, Fe ²⁺ ) ₂ Al (SiAl) O ₅ (OH) ₄ 160 Carlosturanit (Mg, Fe ²⁺ , Ti) ₂₁ (Si, Al) ₁₂ O ₂₈ (OH) ₃₄ · H2O 161 Pyrosmalith- (Fe) (Fe ²⁺ , Mn) ₈ Si ₆ O ₁₅ (Cl, OH) ₁₀ 162 Pyrosmalith- (Mn) (Mn, Fe ²⁺ ) ₈ Si ₆ O ₁₅ (OH, Cl) ₁₀ 163 Brokenhillit (Mn, Fe) ₈ Si ₆ O ₁₅ (OH, Cl) ₁₀ 164 Nelenit (Mn, Fe ²⁺ ) ₁₆ Si ₁₂ As ³⁺ ₃ O ₃₆ (OH) ₁₇ 165 Schallerit (Mn ²⁺ , Fe ²⁺ ) ₁₆ Si ₁₂ As ³⁺ ₃ O ₃₆ (OH) ₁₇ 166 Friedelite Mn ²⁺ ₈ Si ₆ O ₁₅ (OH, Cl) ₁₀ 167 Mcgillit Mn ²⁺ ₈ Si ₆ O ₁₅ (OH) ₈ Cl ₂ 168 Bementit Mn ₇ Si ₆ O ₁₅ (OH) ₈ 169 Varennesit Na ₈ (Mn, Fe ^3+, Ti) ₂ [(OH, Cl) ₂ | (Si ₂ O _{5) 5]} · 12H ₂ O 170 Naujakasit Na ₆ (Fe ²⁺ Mn) Al ₄ Si ₈ O ₂₆ 171 Manganonaujakasit Na ₆ (Mn ²⁺ , Fe ²⁺ ) Al ₄ [Si ₈ O ₂₆ ] 172 Spodiophyllit (Na, K) ₄ (Mg, Fe ²⁺ ) ₃ (Fe ³⁺ , Al) ₂ (Si ₈ O ₂₄ ) 173 Sazhinit- (Ce) Na ₂ CeSi ₆ O ₁₄ (OH) .nH ₂ O 174 Sazhinit- (La) Na ₃ La [Si ₆ O ₁₅ ] .2H ₂ O 175 Burckhardtit Pb ₂ (Fe ³⁺ Te ⁶⁺ ) [AlSi ₃ O ₈ ] O ₆ 176 Tuperssuatsiaite Na ₂ (Fe ³⁺ , Mn ²⁺ ) ₃ Si ₈ O ₂₀ (OH) ₂ .4H ₂ O. 177 palygorskite (Mg, Al) ₂ Si ₄ O ₁₀ (OH) .4H ₂ O. 178 Yofortierit Mn ²⁺ ₅ Si ₈ O ₂₀ (OH) ₂ .7H ₂ O. 179 sepiolite Mg ₄ Si ₆ O ₁₅ (OH) ₂ .6H ₂ O 180 Falcondoit (Ni, Mg) ₄ Si ₆ O ₁₅ (OH) ₂ .6H ₂ O 181 Loughlinit Na ₂ Mg ₃ Si ₆ O ₁₆ .8H ₂ O 182 Kalifersit (K, Na) ₅ Fe ₇ ³⁺ [(OH) ₃ | Si ₁₀ O ₂₅ ] ₂ · 12H ₂ O 183 Minehillit (K, Na) _2-3 Ca ₂₈ (Zn ₄ Al ₄ Si ₄₀ ) O ₁₁₂ (OH) ₁₆ 184 truscottite (Ca, Mn) ₁₄ Si ₂₄ O ₅₈ (OH) ₈ .2H ₂ O 185 Orlymanit Ca ₄ Mn ₃ ²⁺ Si ₈ O ₂₀ (OH) ₆ .2H ₂ O. 186 fedorite (Na, K) _2-3 (Ca, Na) ₇ [Si ₄ O ₈ (F, Cl, OH) 2 | (Si ₄ O ₁₀ ) ₃ ]. 3.5H ₂ O 187 Reyerit (Na, K) ₄ Ca ₁₄ Si ₂₂ Al ₂ O ₅₈ (OH) ₈ .6H ₂ O 188 Gyrolith NaCa ₁₆ Si ₂₃ AlO ₆₀ (OH) ₈ .14H ₂ O 189 Tungusit Ca ₁₄ Feg ²⁺ [(OH) ₂₂ | (Si ₄ O ₁₀ ) ₆ ] 190 Zeophyllit Ca ₄ Si ₃ O ₈ (OH, F) ₄ · 2H ₂ O. 191 Armstrongit CaZr (Si ₆ O ₁₅ ) .3H ₂ O 192 Jagoit Pb ₁₈ Fe ³⁺ ₄ [Si ₄ (Si, Fe ³⁺ ) ₆ ] [Pb ₄ Si ₁₆ (Si, Fe) ₄ ] O ₈₂ Cl ₆ 193 Hyttsjöit Pb ₁₈ Ba ₂ Ca ₅ Mn ₂ ²⁺ Fe ₂ ³⁺ [Cl | (Si ₁₅ O ₄₅ ) ₂ ] .6H ₂ 0 194 Maricopait Ca ₂ Pb ₇ (Si ₃₆ , Al ₁₂ ) (O, OH) ₉₉ · n (H ₂ O, OH) 195 Cavansit Ca (VO) Si ₄ O ₁₀ .4H ₂ O 196 Pentagonit Ca (VO) Si ₄ O ₁₀ .4H ₂ O 197 Weeksit (K, Ba) ₂ [(UO ₂ ) ₂ | Si ₅ O ₁₃ ] .4H ₂ O 198 Coutinhoit Th _0.5 (UO ₂ ) ₂ Si ₅ O ₁₃ .3H ₂ O 199 Haiweeit Ca [(UO _{2) 2} | Si ₅ O ₁₂ (OH) _2] · 6H ₂ O 200 Metahaiweeit Ca (UO ₂ ) ₂ Si ₆ O ₁₅ .nH ₂ O 201 Monteregianit- (Y) KNa ₂ YSi ₈ O ₁₉ · 5H ₂ O 202 Mountainit KNa ₂ Ca ₂ [Si ₈ O ₁₉ (OH)] .6H ₂ O 203 Rhodesit KHCa ₂ Si ₈ O ₁₉ .5H ₂ O 204 Delhayelith K ₇ Na ₃ Ca ₅ Al ₂ Si ₁₄ O ₃₈ F ₄ Cl ₂ 205 Hydrodelhayelith KCa ₂ AlSi ₇ O ₁₇ (OH) ₂ 6H ₂ O 206 Macdonaldit BaCa ₄ Si ₁₆ O ₃₆ (OH) ₂ .10H ₂ O 207 known Cymrite Ba (Si, Al) ₄ (O, OH) ₈ .H ₂ O 208 Kampfit Ba ₁₂ (Si ₁₁ Al ₅ ) O ₃₁ (CO ₃ ) ₈ Cl ₅ 209 Lourenswalsit (K, Ba) ₂ (Ti, Mg, Ca, Fe) ₄ (Si, Al, Fe) ₆ O ₁₄ (OH) ₁₂ 210 Tienshanit (Na, K) _9-10 (Ca, Y) ₂ Ba ₆ (Mn ²⁺ , Fe ²⁺ , Ti ⁴⁺ , Zn) ₆ (Ti, Nb) [(O, F, OH) ₁₁ | B ₂ O ₄ | Si ₆ O ₁₅ ] ₆ 211 Wickenburgit Pb ₃ CaAl [Si ₁₀ O _27] · 3H ₂ O 212 Silhydrit Si ₃ O ₆ .H ₂ O 213 magadiite Na ₂ Si ₁₄ O ₂₉ · 11H ₂ O 214 stratlingite Ca ₂ Al [(OH) ₅ AlSiO ₂ (OH) ₄ ] .2.2 H ₂ O 215 Vertumnit Ca ₄ Al ₄ Si ₄ O ₆ (OH) ₂₄ .3H ₂ O 216 Zussmanit K (Fe ²⁺ , Mg, Mn) ₁₃ (Si, Al) ¹⁸ O ₄₂ (OH) ₁₄ 217 Coombsit K (Mn ²⁺ , Fe ²⁺ , Mg) ₁₃ [(OH) ₇ | (Si, Al) ₃ O ₃ | Si ₆ O ₁₈ ] ₂

1. a) cf. Mineral atlas, mineral class VIII / H - phyllosilicates (phyllosilicates), Strunz 8 classification

Is very particularly preferably bentonite from the group of montmorillonites ((Na, Ca) _0.3 (Al, Mg) ₂ Si ₄ O ₁₀ (OH) ₂ · nH ₂ O). Bentonite is a mixture of various clay minerals and contains montmorillonite as its main constituent. For example, sodium bentonite absorbs water, it can absorb a variety of its own dry weight. Furthermore, calcium bentonite can absorb fats and / or oils.

The layered silicate micro- and / or nanoparticles described above are functionalized, non-functionalized, aggregated, non-aggregated, agglomerated, non-agglomerated, supported and / or unsupported. For example, they may be functionalized, agglomerated and supported. But they can also not be functionalized and aggregated.

Examples of other suitable ingredients (E) are:

• • lactose, cellulose, starches, sucrose (tablets)
• • paraffin (ointments); Hard fat (uvula)
• Polyethylene glycols (macrogols, PEG); Polyethylene oxides (PEO) (tablets, ointments, creams);
• • solvent and / or humectant: vcwater, ethanol, isopropanol (granulation, film spray)
• Emulsifiers: cetylstearyl alcohol, glycerol monostearate, lecithin, fatty acid esters of sorbitan, polyoxyethylene sorbitan (polysorbates), polyoxyethylene, polyoxyethylene fatty alcohol ethers (emulsions, creams), methyl glucose, sesquistearates, stearic acid and derivatives thereof, acrylate-based emulsifiers, e.g. Acrylates / C10-330 Alkyl Acrylate Crosspolymer
• Solubilizers and / or wetting agents: polyethylene glycols (PEG, macrogols), polyethylene oxides (PEO, PolyOx), polysorbates (solutions, suspensions)
• • Buffers: dipotassium hydrogen phosphate, sodium dihydrogen phosphate, sodium bicarbonate, calcium hydrogen phosphate, trometamol (solutions, creams)
• Thickeners and binders: starches, guar gum, xanthan gum, alginate, carrageenan, pectin, tragacanth, polyacrylic acids, polyvinylpyrrolidone (granules, tablets); fumed silica, substituted cellulose ethers (methylcellulose, ethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, Carboxymethylcellulose) (tablets, gels, viscous solutions), Butyrospermum Parkii butter, MAGNESIUM SULFATE
• • wrapping agent: sucrose (sugar dragee); Gelatin (capsules); Gelatin polysuccinate ("soft capsules"), polyacrylates, ethylcellulose, methylcellulose (filmcoating: film capsules, film-coated tablets, pellets)
• • disintegrants and / or disintegrants: starches (tablets, tabs); Croscarmellosis (tablets, capsules, granules); Sodium bicarbonate in combination with citric acid (effervescent tablets)
• Lubricants and / or mold release agents: polyethylene glycols (PEG, macrogols), polyethylene oxides (PEO), talc, magnesium stearate (tableting)
• Flow control agent: fumed silica (powders, granules)
• • Antioxidants: butylhydroxytoluene, all-rac-α-tocopherol
• • Preservatives: PHB esters, benzalkonium chloride, benzyl alcohol, thiomersal
• • Sweeteners, flavoring agents: sucrose, sorbitol, sweeteners such as saccharin sodium and cyclamate
• • flavors
• • absorption accelerator: dimethyl sulphoxide (in topical preparations)

Other aids include

• • ACETIC ACID Essigsäure
• • AMINOMETHYL PROPANOL 2-Amino-2-methylpropanol
• • AMMONIA Ammoniak
• • AMMONIUM BICARBONATE Ammoniumbicarbonat, Ammoniumhydrogencarbonat
• • AMMONIUM CARBONATE Ammoniumcarbonat
• • CITRIC ACID Zitronensäure, Citronensäure
• • DISODIUM PHOSPHATE Dinatriumhydrogenphosphat
• • DISODIUM PYROPHOSPHATE Dinatriumdihydrogenpyrophosphat
• • ETHANOLAMINE Ethanolamin, 2-Aminoethanol
• • HYDROCHLORIC ACID Salzsäure, Chlorwasserstoff
• • PHOSPHORIC ACID Phosphorsäure
• • POTASSIUM CITRATE Kaliumcitrat
• • POTASSIUM PHOSPHATE Kaliumdihydrogenphosphat
• • SODIUM ACETATE Natriumacetat, Natriumsalz der Essigsäure
• • SODIUM BICARBONATE Natriumbicarbonat, Natron, Natriumhydrogencarbonat
• • SODIUM CITRATE Natriumcitrat (Natriumsalz der Citronensäure)
• • SODIUM HYDROXIDE Natriumhydroxid, Natronlauge
• • SODIUM METAPHOSPHATE Natriummetaphosphat
• • SODIUM PHOSPHATE Natriumdihydrogenphosphat
• • SODIUM TRIMETAPHOSPHATE Trinatriumtrimetaphosphat
• • TETRAPOTASSIUM PYROPHOSPHATE Kaliumpyrophosphat
• • TETRASODIUM PYROPHOSPHATE Natriumpyrophosphat
• • TRIETHANOLAMINE Tris(2-hydroxyethyl)amin, Trihydroxytriethylamin Antioxidantien
• • ASCORBIC ACID Vitamin C, Ascorbinsäure
• • ASCORBYL PALMITATE Palmitinsäureascorbylester, L-Ascorbylpalmitat
• • BHT Butylhydroxytoluol, 2,6-Di-t-butyl-p-cresol
• • CAROTENOIDS Carotinoide
• • LYCOPENE Lycopin
• • TOCOPHEROL alpha-Tocopherol, Vitamin E
• • TOCOPHERYL ACETATE alpha-Tocopherylacetat (Vitamin-E-Acetat)
• • UBIQUINONE Q10, Coenzym Q10; Ubichinon-10
• • RUTIN Bindemittel
• • Alkydharze
• • Emulsionen
• • Epoxidharze
• • gebrannter Kalk, Zement, Lehm und Kaliwasserglas
• • Gummi arabicum
• • Harze
• • Honig
• • Kasein
• • Kunststoffdispersionen
• • Pflanzenöle (Leinöl, Avocadoöl, Weizenkeimöl, Mandelöl, Lavendelöl))
• • Polyurethane
• • Rosmarin
• • Silikonharz
• • Wachs
• • Zelluloseleim (Kleister) Farbstoffe/Farbpigmente
• • Natrium-4-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1 H-pyrazol-4-yl)azo]-3-hydroxynaphthalin-1-sulfonat
• • Dihydroxyaluminiumstearat
• • Anthocyane (Cyanidin, Peonidin, Malvidin, Delphinidin, Petunidin, Pelargonidin)
• • Rote Bete; Rote Rübe; Zuckerrübe
• • Bromkresolgrün
• • Bromthymolblau
• • Calciumstearat
• • Paprikaextrakt; Capsanthin, Capsorubin
• • Karamell, Zuckerkulör
• • 1,4-Bis(p-tolylamino)anthrachinon
• • Natrium-1 -amino-4-(cyclohexylamino)-9, 10-dihydro-9, 10-dioxoanthracen-2-sulfonat
• • Indigo; 2-(1,3-Dihydro-3-oxo-2H-indazol-2-yliden)-1,2-dihydro-3H-indol-3-on
• • Dinatrium[29H,31H-phthalocyanindisulfonato(4-)-N29,N30,N31 ,N32]cuprat(2-)
• • Polychlorkupferphthalocyanin
• • Guanin; 2-Amino-6-hydroxypurin; 2-Amino-1,7-dihydro-6H-purin-6-on
• • Kurkumin, Curcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-dien-3,5-dion
• • Karmin; Karminsäure
• • Chlorophyll; Chlorophyll a/b; Trinatrium-(2S-trans)-[18-carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphin-2-propionato(5-) N21, N22,N23,N24]cuprat(3-)
• • Aluminium
• • Aluminiumoxidhydrat; Aluminiumhydroxid
• • Wasserhaltiges Aluminiumsilicat
• • Lazurit; Ultramarin
• • Aluminumsilicat, gefärbt durch Eisen(III)oxid
• • Bariumsulfat
• • Bismutchloridoxid
• • Calciumcarbonat; Kalziumkarbonat; Kreide
• • Calciumsulfat; Kalziumsulfat
• • Kohlenstoff; synthetischer Ruß; „Carbon Black“
• • Kohlenstoff; synthetischer Ruß; „Carbon Black“ (nanoskalig)
• • Knochenkohle
• • Pflanzenkohle
• • Chrom(III)oxid; Chromoxidgrün
• • Chrom(III)oxid-Dihydrat; Chromoxidhydratgrün
• • Kobaltaluminiumoxid; Kobaltblau
• • Kupfer
• • Gold
• • Eisen(II)oxid
• • Eisen(III)oxid
• • Eisen(III)oxid-Hydrat
• • Eisen(II,III)oxid
• • Preußisch Blau, Eisen(III)hexacyanoferrat
• • Magnesiumcarbonat
• • Manganviolett; Ammoniummangan(III)diphosphat
• • Mangan(II)phosphat-Heptahydrat
• • Silber
• • Titandioxid
• • Zinkoxid
• • LACTOFLAVIN Lactoflavin; Riboflavin
• • MAGNESIUM STEARATE Magnesiumdistearat
• • RIBOFLAVIN Riboflavin; Lactoflavin
• • ZINC STEARATE Zinkstearat Feuchthaltemittel
• • CYCLOMETHICONE Cyclomethicon; besteht aus Octamethylcyclotetrasiloxan (D4), Decamethylcyclopentasiloxan (D5) und Dodecamethylcyclohexasiloxan (D6)
• • CYCLOPENTASILOXANE Decamethylcyclopentasiloxan
• • GLYCERIN Glycerin, Glycerol, 1,2,3-Propantriol
• • GLYCOL Glykol, Ethylenglycol, Ethylenglykol
• • LACTIC ACID Milchsäure; 2-Hydroxypropionsäure, 2-Hydroxypropansäure
• • y-6 Polyethylenglycol (durchschnittlich 6 Einheiten -CH2-CH2-O-)
• • SODIUM LACTATE Natriumlactat (Natriumsalz der Milchsäure)
• • SODIUM HYALURONATE
• • SORBITOL Sorbit, Sorbitol, Glucitol
• • PANTHENOL (Provitamin B5)
• • CAMELLIA EURYOIDES LEAF EXTRACT Harze
• • POLYMETHACRYLIC ACID Polymethacrylsäure
• • POLYVINYL ACETATE Polyvinylacetat
• • TOSYLAMIDE/FORMALDEHYDE RESIN Toluolsulfonamid-Formaldehydharz Konservierungsmittel
• • 2-BROMO-2-NITROPROPANE-1,3-DIOL 2-Brom-2-nitropropan-1,3-diol, Bronopol
• • 4-HYDROXYBENZOIC ACID 4-Hydroxybenzoesäure
• • 5-BROMO-5-NITRO-1,3-DIOXANE 5-Brom-5-nitro-1,3-dioxan
• • AMMONIUM BENZOATE Ammoniumbenzoat, Ammoniumsalz der Benzoesäure
• • AMMONIUM BISULFITE Ammoniumbisulfit, Ammoniumhydrogensulfit
• • AMMONIUM PROPIONATE Ammoniumpropionat, Ammoniumsalz der Propionsäure
• • AMMONIUM SULFITE Ammoniumsulfit
• • BENZALKONIUM BROMIDE Benzalkoniumbromid
• • BENZALKONIUM CHLORIDE Benzalkoniumchlorid
• • BENZETHONIUM CHLORIDE Benzethoniumchlorid
• • BENZOIC ACID Benzoesäure
• • BENZYL ALCOHOL Benzylalkohol; Phenylmethanol
• • BROMOCHLOROPHENE Bromchlorophen
• • BUTYL BENZOATE Benzoesäure-Butylester
• • BUTYLPARABEN Butylparaben; 4-Hydroxybenzoesäurebutylester
• • CALCIUM BENZOATE Calciumbenzoat, Calciumsalz der Benzoesäure
• • CALCIUM PARABEN 4-Hydroxybenzoesäure, Calciumsalz
• • CALCIUM PROPIONATE Calciumpropionat, Calciumsalz der Propionsäure
• • CALCIUM SALICYLATE Calciumsalicylat, Calciumsalz der Salicylsäure
• • CALCIUM SORBATE Calciumsorbat, Calciumsalz der Sorbinsäure
• • CETRIMONIUM CHLORIDE Cetrimoniumchlorid
• • CHLORHEXIDINE Chlorhexidin
• • CHLOROACETAMIDE Chloracetamid
• • CHLOROBUTANOL Chlorbutanol
• • CHLOROPHENE Chlorophen, 4-Chlor-2-(phenylmethyl)phenol
• • CHLORPHENESIN Chlorphenesin, 3-(4-Chlorphenoxy)-1,2-propandiol
• • CLIMBAZOLE Climbazol, 1-(4-Chlorphenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl-2-butanon
• • DEHYDROACETIC ACID Dehydracetsäure, 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dion
• • DIAZOLIDINYL UREA Diazolidinylharnstoff
• • DMDM HYDANTOIN 1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidin-2,4-dion
• • ETHYL BENZOATE Benzoesäure-Ethylester
• • ETHYLPARABEN Ethylparaben; 4-Hydroxybenzoesäureethylester
• • FORMALDEHYDE Formaldehyd, Methanal, Formalin
• • FORMIC ACID Ameisensäure
• • GLUTARAL Glutaral, Glutardialdehyd
• • HEXAMIDINE Hexamidin
• • IMIDAZOLIDINYL UREA Imidazolidinyl-Harnstoff
• • IODOPROPYNYL BUTYLCARBAMATE 3-lod-2-propinylbutylcarbamat
• • ISOBUTYL BENZOATE Benzoesäure-Isobutylester
• • ISOPROPYL BENZOATE Benzoesäure-Isopropylester
• • ISOPROPYL CRESOLS 4-Isopropyl-m-cresol
• • MAGNESIUM BENZOATE Magnesiumbenzoat, Magnesiumsalz der Benzoesäure
• • MAGNESIUM PROPIONATE Magnesiumpropionat, Magnesiumsalz der Propionsäure
• • MAGNESIUM SALICYLATE Magnesiumsalicylat, Magnesiumsalz der Salicylsäure
• • MEA-BENZOATE Benzoesäure, (Mono-)Ethanolaminsalz
• • METHYL BENZOATE Benzoesäure-Methylester
• • METHYLCHLOROISOTHIAZOLINONE Chlormethylisothiazolinon, Methylchlorisothiazolinon; 5-Chlor-2-methyl-2H-isothiazol-3-on
• • METHYLISOTHIAZOLINONE Methylisothiazolinon, 2-Methyl-2H-isothiazol-3-on
• • METHYLPARABEN Methylparaben; 4-Hydroxybenzoesäuremethylester
• • O-PHENYLPHENOL o-Phenylphenol
• • P-CHLORO-M-CRESOL 4-Chlor-3-methylphenol, p-Chlor-m-cresol
• • PHENOXYETHANOL 2-Phenoxyethanol
• • PHENOXYISOPROPANOL Phenoxyisopropanol, 1-Phenoxypropan-2-ol
• • PHENYL BENZOATE Benzoesäure-Phenylester
• • PIROCTONE OLAMINE Pirocton-Olamin
• • POTASSIUM BENZOATE Kaliumbenzoat, Kaliumsalz der Benzoesäure
• • POTASSIUM BUTYLPARABEN Butylparaben (Kaliumsalz); 4-Hydroxybenzoesäurebutylester (Kaliumsalz)
• • POTASSIUM ETHYLPARABEN Ethylparaben (Kaliumsalz); 4-Hydroxybenzoesäureethylester (Kaliumsalz)
• • POTASSIUM METABISULFITE Dikaliumdisulfit
• • POTASSIUM METHYLPARABEN Methylparaben (Kaliumsalz); 4-Hydroxybenzoesäuremethylester (Kaliumsalz)
• • POTASSIUM PARABEN 4-Hydroxybenzoesäure, Kaliumsalz
• • POTASSIUM PROPIONATE Kaliumpropionat, Kaliumsalz der Propionsäure
• • POTASSIUM PROPYLPARABEN Propylparaben (Kaliumsalz); 4-Hydroxybenzoesäurepropylester (Kaliumsalz)
• • POTASSIUM SALICYLATE Kaliumsalicylat, Kaliumsalz der Salicylsäure
• • POTASSIUM SORBATE Kaliumsorbat, Kaliumsalz der Sorbinsäure
• • POTASSIUM SULFITE Kaliumsulfit
• • PROPIONIC ACID Propionsäure
• • PROPYL BENZOATE Benzoesäure-Propylester
• • PROPYLPARABEN Propylparaben; 4-Hydroxybenzoesäurepropylester
• • SODIUM BENZOATE Natriumbenzoat, Natriumsalz der Benzoesäure
• • SODIUM BISULFITE Natriumbisulfit, Natriumhydrogensulfit
• • SODIUM BUTYLPARABEN Butylparaben (Natriumsalz); 4-Hydroxybenzoesäurebutylester (Natriumsalz)
• • SODIUM ETHYLPARABEN Ethylparaben (Natriumsalz); 4-Hydroxybenzoesäureethylester (Natriumsalz)
• • SODIUM FORMATE Natriumformiat, Natriumsalz der Ameisensäure
• • SODIUM METABISULFITE Dinatriumdisulfit, Natriummetabisulfit
• • SODIUM METHYLPARABEN Methylparaben (Natriumsalz); 4-Hydroxybenzoesäuremethylester (Natriumsalz)
• • SODIUM PARABEN 4-Hydroxybenzoesäure, Natriumsalz
• • SODIUM PROPIONATE Natriumpropionat, Natriumsalz der Propionsäure
• • SODIUM PROPYLPARABEN Propylparaben (Natriumsalz); 4-Hydroxybenzoesäurepropylester (Natriumsalz)
• • SODIUM SALICYLATE Natriumsalicylat, Natriumsalz der Salicylsäure
• • SODIUM SORBATE Natriumsorbat, Natriumsalz der Sorbinsäure
• • SODIUM SULFITE Natriumsulfit
• • SORBIC ACID Sorbinsäure, 2,4-Hexadiensäure
• • STEARALKONIUM CHLORIDE Stearalkoniumchlorid
• • TRICLOCARBAN Triclocarban, 1-(4-Chlorphenyl)-3-(3,4-dichlorphenyl)harnstoff
• • TRICLOSAN Triclosan, 5-Chlor-2-(2,4-dichlorphenoxy)phenol Oxidationsmittel
• • AMMONIUM PERSULFATE Ammoniumperoxodisulfat, Ammoniumpersulfat
• • HYDROGEN PEROXIDE Wasserstoffperoxid
• • POTASSIUM PERSULFATE Kaliumpersulfat, Kaliumperoxodisulfat
• • SODIUM PERSULFATE Natriumpersulfat, Natriumperoxodisulfat Reduktionsmittel
• • AMMONIUM BISULFITE Ammoniumbisulfit, Ammoniumhydrogensulfit
• • AMMONIUM THIOGLYCOLATE Ammoniumthioglycolat, Ammoniummercaptoacetat
• • SODIUM METABISULFITE Dinatriumdisulfit, Natriummetabisulfit
• • THIOGLYCOLIC ACID Thioglykolsäure, Thioglycolsäure; Mercaptoessigsäure
• • THIOLACTIC ACID Thiomlichsäure, 2-Mercaptopropionsäure Stabilisatoren
• • ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER Polymer aus Acrylsäurealkylestern (C10-C30), Acrylsäure, Methacrylsäure und/oder anderen Alkylacrylaten; kreuzverknpüft mit Propenyl-(allyl-)modifizierten Zuckern
• • ASCORBYL PALMITATE Palmitinsäureascorbylester, L-Ascorbylpalmitat
• • BENTONITE Bentonit (Tonmineral)
• • BHT Butylhydroxytoluol, 2,6-Di-t-butyl-p-cresol
• • CARBOMER Polyacrylsäure
• • CETEARYL ALCOHOL Cetearylalkohol, Mischung aus 1-Hexadecanol (Cetylalkohol) und 1-Octadecanol (Stearylalkohol)
• • CETYL HYDROXYETHYLCELLULOSE 2-Hydroxyethylcellulose-Cetyl-Ether
• • COCAMIDE MEA N-(Hydroxyethyl)-Kokosfettsäureamid
• • DISODIUM EDTA Ethylendiamintetraessigsäure, Dinatriumsalz
• • EDTA Ethylendiamintetraessigsäure
• • ETIDRONIC ACID Etidronsäure, 1-Hydroxyethyliden-bis-phosphonsäure
• • HYDROXYETHYLCELLULOSE Hydroxyethylcellulose
• • MICROCRYSTALLINE CELLULOSE Cellulose (mikrokristallin)
• • PENTASODIUM PENTETATE Pentanatrium(carboxylatomethyl)iminobis(ethylennitrilo)tetraacetat
• • POTASSIUM ALGINATE Kaliumalginat (Kaliumsalz der Alginsäure)
• • PVP Polyvinylpyrrolidon
• • SODIUM CARBOMER Polyacrylsäure (Natriumsalze)
• • SODIUM CITRATE Natriumcitrat (Natriumsalz der Citronensäure)
• • SODIUM GLUCONATE Natriumgluconat (Natriumsalz der Gluconsäure)
• • TETRASODIUM EDTA Ethylendiamintetraessigsäure, Tetranatriumsalz
• • TOCOPHEROL alpha-Tocopherol, Vitamin E
• • TRISODIUM EDTA Ethylendiamintetraessigsäure, Trinatriumsalz
• • Polysaccharide Treibgase für Sprays
• • Butan
• • Kohlendioxid
• • Dimethylether
• • Isobutan, 2-Methylpropan
• • Stickstoff
• • Propan

Alkalizing / acids / neutralizing agent

• • ACETIC ACID acetic acid
• • AMINOMETHYL PROPANOL 2-amino-2-methylpropanol
• • AMMONIA ammonia
• • AMMONIUM BICARBONATE Ammonium bicarbonate, ammonium bicarbonate
• • AMMONIUM CARBONATE ammonium carbonate
• • CITRIC ACID citric acid, citric acid
• • DISODIUM PHOSPHATE disodium hydrogen phosphate
• • DISODIUM PYROPHOSPHATE disodium dihydrogen pyrophosphate
• • ETHANOLAMINE Ethanolamine, 2-aminoethanol
• • HYDROCHLORIC ACID hydrochloric acid, hydrogen chloride
• • PHOSPHORIC ACID phosphoric acid
• • POTASSIUM CITRATE potassium citrate
• • POTASSIUM PHOSPHATE potassium dihydrogen phosphate
• • SODIUM ACETATE sodium acetate, sodium salt of acetic acid
• • SODIUM BICARBONATE Sodium bicarbonate, sodium bicarbonate, sodium bicarbonate
• SODIUM CITRATE Sodium citrate (sodium salt of citric acid)
• • SODIUM HYDROXIDE sodium hydroxide, caustic soda
• • SODIUM METAPHOSPHATE Sodium metaphosphate
• • SODIUM PHOSPHATE Sodium dihydrogen phosphate
• • SODIUM TRIMETAPHOSPHATE trisodium trimetaphosphate
• • TETRAPOTASSIUM PYROPHOSPHATE Potassium pyrophosphate
• • TETRASODIUM PYROPHOSPHATE Sodium pyrophosphate
• • TRIETHANOLAMINE tris (2-hydroxyethyl) amine, trihydroxytriethylamine antioxidants
• • ASCORBIC ACID Vitamin C, ascorbic acid
• • ASCORBYL PALMITATE Ascorbyl palmitate, L-ascorbyl palmitate
• BHT butylhydroxytoluene, 2,6-di-t-butyl-p-cresol
• • CAROTENOIDS carotenoids
• • LYCOPENE lycopene
• • TOCOPHEROL alpha tocopherol, vitamin E
• TOCOPHERYL ACETATE alpha tocopheryl acetate (vitamin E acetate)
• • UBIQUINONE Q10, Coenzyme Q10; Coenzyme Q10
• • RUTIN binder
• • Alkyd resins
• • emulsions
• • epoxy resins
• • burned lime, cement, clay and potash water
• • Gum arabic
• • Resins
• • honey
• • Casein
• • plastic dispersions
• • vegetable oils (linseed oil, avocado oil, wheat germ oil, almond oil, lavender oil))
• • Polyurethanes
• • rosemary
• • silicone resin
• • Wax
• • Cellulose glue (paste) dyes / color pigments
• Sodium 4 - [(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl) azo] -3-hydroxynaphthalene-1-sulfonate
• • Dihydroxyaluminum stearate
• • anthocyanins (cyanidin, peonidin, malvidin, delphinidin, petunidin, pelargonidin)
• • Beetroot; Red beet; sugar beet
• • Bromocresol green
• • Bromothymol blue
• • calcium stearate
• • paprika extract; Capsanthin, Capsorubin
• • caramel, caramel
• • 1,4-bis (p-tolylamino) anthraquinone
• Sodium 1-amino-4- (cyclohexylamino) -9,10-dihydro-9,10-dioxoanthracene-2-sulfonate
• • Indigo; 2- (1,3-dihydro-3-oxo-2H-indazol-2-ylidene) -1,2-dihydro-3H-indol-3-one
• Disodium [29H, 31H-phthalocyaninedisulfonato (4 -) - N29, N30, N31, N32] cuprate (2-)
• • Polychloroprole phthalocyanine
• • Guanine; 2-amino-6-hydroxypurine; 2-amino-1,7-dihydro-6H-purin-6-one
• Curcumin, curcumin; 1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-dien-3,5-dione
• • Carmine; carminic
• • chlorophyll; Chlorophyll a / b; Trisodium (2S-trans) - [18-carboxy-20- (carboxymethyl) -13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H, 23H-porphine-2 Propionato (5-) N21, N22, N23, N24] cuprate (3-)
• • aluminum
• • alumina hydrate; aluminum hydroxide
• • hydrous aluminum silicate
• • Lazurite; ultramarine
• • Aluminosilicate stained by ferric oxide
• • Barium sulphate
• • bismuth chloride oxide
• Calcium carbonate; Calcium carbonate; chalk
• Calcium sulfate; calcium sulphate
• • carbon; synthetic carbon black; "Carbon Black"
• • carbon; synthetic carbon black; "Carbon Black" (nanoscale)
• • Bone coal
• • biochar
• Chromium (III) oxide; Chrome Oxide
• Chromium (III) oxide dihydrate; Viridian
• Cobalt-aluminum oxide; cobalt blue
• • copper
• • Gold
• • Iron (II) oxide
• • iron (III) oxide
• • Iron (III) oxide hydrate
• • Iron (II, III) oxide
• • Prussian blue, ferric hexacyanoferrate
• • Magnesium carbonate
• • manganese violet; diphosphate ammonium manganese (III)
• • Manganese (II) phosphate heptahydrate
• • silver
• • titanium dioxide
• • zinc oxide
• • LACTOFLAVIN lactoflavin; riboflavin
• • MAGNESIUM STEARATE magnesium distearate
• • RIBOFLAVIN Riboflavin; lactoflavin
• • ZINC STEARATE zinc stearate humectant
• CYCLOMETHICONE cyclomethicone; Composed of octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5) and dodecamethylcyclohexasiloxane (D6)
• • CYCLOPENE-AOXANE decamethylcyclopentasiloxane
• • GLYCERINE Glycerol, glycerol, 1,2,3-propanetriol
• • GLYCOL glycol, ethylene glycol, ethylene glycol
• • LACTIC ACID Lactic Acid; 2-hydroxypropionic acid, 2-hydroxypropanoic acid
• Y-6 polyethylene glycol (average 6 units -CH 2 -CH 2 -O-)
• SODIUM LACTATE Sodium lactate (sodium salt of lactic acid)
• • SODIUM HYALURONATES
• • Sorbitol sorbitol, sorbitol, glucitol
• • PANTHENOL (provitamin B5)
• • CAMELLIA EURYOIDES LEAF EXTRACT Resins
• • POLYMETHACRYLIC ACID polymethacrylic acid
• • POLYVINYL ACETATE polyvinyl acetate
• • TOSYLAMIDE / FORMALDEHYDE RESIN Toluene sulfonamide formaldehyde resin preservative
• 2-BROMO-2-NITROPROPANE-1,3-DIOL 2-bromo-2-nitropropane-1,3-diol, Bronopol
• 4-HYDROXYBENZOIC ACID 4-hydroxybenzoic acid
• • 5-BROMO-5-NITRO-1,3-DIOXANE 5-bromo-5-nitro-1,3-dioxane
• • AMMONIUM BENZOATE Ammonium benzoate, ammonium salt of benzoic acid
• • AMMONIUM BISULFITE Ammonium bisulfite, ammonium bisulfite
• • AMMONIUM PROPIONATE ammonium propionate, ammonium salt of propionic acid
• • AMMONIUM SULFITE ammonium sulfite
• BENZALKONIUM BROMIDE Benzalkonium bromide
• • BENZALKONIUM CHLORIDE Benzalkonium chloride
• • BENZETHONIUM CHLORIDE Benzethonium chloride
• • BENZOIC ACID benzoic acid
• • BENZYL ALCOHOL Benzyl Alcohol; phenylmethanol
• • BROMOCHLOROPHENE Bromochlorophen
• • BUTYL BENZOATE Benzoic acid butyl ester
• • BUTYLPARABENES Butylparaben; 4-hydroxybenzoate
• • CALCIUM BENZOATE calcium benzoate, calcium salt of benzoic acid
• • CALCIUM PARABEN 4-hydroxybenzoic acid, calcium salt
• • CALCIUM PROPIONATE calcium propionate, calcium salt of propionic acid
• • CALCIUM SALICYLATE calcium salicylate, calcium salt of salicylic acid
• • CALCIUM SORBATE calcium sorbate, calcium salt of sorbic acid
• • CETRIMONIUM CHLORIDE Cetrimonium chloride
• • CHLORHEXIDINE chlorhexidine
• • CHLOROACETAMIDE Chloroacetamide
• • CHLOROBUTANOL Chlorobutanol
• • CHLOROPHENE Chlorophen, 4-chloro-2- (phenylmethyl) phenol
• • CHLOROPHENESINE Chlorphenesin, 3- (4-chlorophenoxy) -1,2-propanediol
• Climazole, 1- (4-chlorophenoxy) -1- (1H-imidazol-1-yl) -3,3-dimethyl-2-butanone
• • DEHYDROACETIC ACID dehydroacetic acid, 3-acetyl-6-methyl-2H-pyran-2,4 (3H) -dione
• • DIAZOLIDINYL UREA Diazolidinyl urea
• DMDM HYDANTOIN 1,3-bis (hydroxymethyl) -5,5-dimethylimidazolidine-2,4-dione
• • ETHYL BENZOATE benzoic acid ethyl ester
• • ETHYLPARABLES Ethylparaben; 4-hydroxybenzoate
• • FORMALDEHYDE formaldehyde, methanal, formalin
• • FORMIC ACID formic acid
• • GLUTARAL glutaral, glutaraldehyde
• • HEXAMIDINE hexamidine
• • IMIDAZOLIDINYL UREA Imidazolidinyl urea
• IOPOPROPYNYL BUTYL CARBAMATE 3-iodo-2-propynyl butyl carbamate
• • ISOBUTYL BENZOATE benzoic acid isobutyl ester
• • ISOPROPYL BENZOATE benzoic acid isopropyl ester
• ISOPROPYL CRESOLS 4-isopropyl-m-cresol
• • MAGNESIUM BENZOATE Magnesium benzoate, magnesium salt of benzoic acid
• • MAGNESIUM PROPIONATE Magnesium Propionate, magnesium salt of propionic acid
• • MAGNESIUM SALICYLATE Magnesium salicylate, magnesium salt of salicylic acid
• • MEA BENZOATE benzoic acid, (mono) ethanolamine salt
• • METHYL BENZOATE benzoic acid methyl ester
• • METHYLCHLOROISOTHIAZOLINONE Chloromethylisothiazolinone, methylchloroisothiazolinone; 5-chloro-2-methyl-2H-isothiazol-3-one
• • METHYLISOTHIAZOLINONE Methylisothiazolinone, 2-methyl-2H-isothiazol-3-one
• • METHYLPARABEN Methylparaben; 4-hydroxybenzoate
• O-PHENYLPHENOL o-phenylphenol
• P-CHLORO-M-CRESOL 4-chloro-3-methylphenol, p-chloro-m-cresol
• PHENOXYETHANOL 2-phenoxyethanol
• • PHENOXYISOPROPANOL Phenoxyisopropanol, 1-phenoxypropan-2-ol
• • PHENYL BENZOATE benzoic acid phenyl ester
• • PIROCTONE OLAMINE Piroctone-Olamin
• • POTASSIUM BENZOATE Potassium benzoate, potassium salt of benzoic acid
• • POTASSIUM BUTYLPARABEN Butylparaben (potassium salt); 4-hydroxybenzoic acid butyl ester (potassium salt)
• • POTASSIUM ETHYLPARABES Ethyl paraben (potassium salt); 4-hydroxybenzoic acid ethyl ester (potassium salt)
• • POTASSIUM METABISULFITE dipotassium disulfite
• • POTASSIUM METHYLPARABEN Methylparaben (potassium salt); 4-hydroxybenzoic acid methyl ester (potassium salt)
• • POTASSIUM PARABEN 4-hydroxybenzoic acid, potassium salt
• • POTASSIUM PROPIONATE potassium propionate, potassium salt of propionic acid
• • POTASSIUM PROPYLPARABEN Propylparaben (potassium salt); 4-hydroxybenzoic acid propyl ester (potassium salt)
• • POTASSIUM SALICYLATE potassium salicylate, potassium salt of salicylic acid
• • POTASSIUM SORBATE potassium sorbate, potassium salt of sorbic acid
• • POTASSIUM SULFITE Potassium sulfite
• • PROPIONIC ACID Propionic Acid
• • PROPYL BENZOATE benzoic acid propyl ester
• • PROPYLPARABLES Propylparaben; 4-hydroxybenzoate
• • SODIUM BENZOATE sodium benzoate, sodium salt of benzoic acid
• • SODIUM BISULFITE sodium bisulfite, sodium hydrogensulfite
• • SODIUM BUTYLPARABEN Butylparaben (sodium salt); 4-hydroxybenzoic acid butyl ester (sodium salt)
• • SODIUM ETHYLPARABES Ethyl paraben (sodium salt); 4-hydroxybenzoic acid ethyl ester (sodium salt)
• • SODIUM FORMATE sodium formate, sodium salt of formic acid
• • SODIUM METABISULFITE disodium disulfite, sodium metabisulfite
• • SODIUM METHYLPARABEN Methylparaben (sodium salt); 4-hydroxybenzoic acid methyl ester (sodium salt)
• • SODIUM PARABEN 4-hydroxybenzoic acid, sodium salt
• • SODIUM PROPIONATE sodium propionate, sodium salt of propionic acid
• • SODIUM PROPYLPARABEN Propylparaben (sodium salt); 4-hydroxybenzoic acid propyl ester (sodium salt)
• • SODIUM SALICYLATE Sodium salicylate, sodium salt of salicylic acid
• • SODIUM SORBATE sodium sorbate, sodium salt of sorbic acid
• • SODIUM SULFITE sodium sulfite
• • SORBIC ACID sorbic acid, 2,4-hexadienoic acid
• • STEARAL CONCENTRATE CHLORIDE Stearalkonium chloride
• Triclocarban, 1- (4-chlorophenyl) -3- (3,4-dichlorophenyl) urea
• TRICLOSAN triclosan, 5-chloro-2- (2,4-dichlorophenoxy) phenol oxidizing agent
• • AMMONIUM PERSULFATE Ammonium peroxodisulfate, ammonium persulfate
• • HYDROGEN PEROXIDE hydrogen peroxide
• • POTASSIUM PERSULFATE potassium persulfate, potassium peroxodisulfate
• • SODIUM PERSULFATE Sodium persulfate, sodium peroxodisulfate reducing agent
• • AMMONIUM BISULFITE Ammonium bisulfite, ammonium bisulfite
• • AMMONIUM THIOGLYCOLATE Ammonium thioglycolate, ammonium mercaptoacetate
• • SODIUM METABISULFITE disodium disulfite, sodium metabisulfite
• • THIOGLYCOLIC ACID Thioglycolic acid, thioglycolic acid; mercaptoacetic
• • THIOLACTIC ACID thiomic acid, 2-mercaptopropionic acid stabilizers
• • ACRYLATES / C10-30 ALKYL ACRYLATE CROSSPOLYMER Polymer of acrylic acid alkyl esters (C10-C30), acrylic acid, methacrylic acid and / or other alkyl acrylates; cross-linked with propenyl (allyl) modified sugars
• • ASCORBYL PALMITATE Ascorbyl palmitate, L-ascorbyl palmitate
• • BENTONITE bentonite (clay mineral)
• BHT butylhydroxytoluene, 2,6-di-t-butyl-p-cresol
• • CARBOMER polyacrylic acid
• • CETEARYL ALCOHOL Cetearyl alcohol, mixture of 1-hexadecanol (cetyl alcohol) and 1-octadecanol (stearyl alcohol)
• • CETYL HYDROXYETHYL CELLULOSE 2-hydroxyethyl cellulose cetyl ether
• COCAMIDE MEA N- (hydroxyethyl) coconut fatty acid amide
• • DISODIUM EDTA Ethylenediaminetetraacetic acid, disodium salt
• • EDTA ethylenediaminetetraacetic acid
• • ETIDRONIC ACID Etidronic acid, 1-hydroxyethylidene bisphosphonic acid
• HYDROXYETHYL CELLULOSE Hydroxyethylcellulose
• • MICROCRYSTALLINE CELLULOSE cellulose (microcrystalline)
• PENTASODIUM PENTETATE Pentasodium (carboxylatomethyl) iminobis (ethylenitrilo) tetraacetate
• • POTASSIUM ALGINATE potassium alginate (potassium salt of alginic acid)
• • PVP polyvinylpyrrolidone
• • SODIUM CARBOMER polyacrylic acid (sodium salts)
• SODIUM CITRATE Sodium citrate (sodium salt of citric acid)
• SODIUM GLUCONATE sodium gluconate (sodium salt of gluconic acid)
• • TETRASODIUM EDTA Ethylenediaminetetraacetic acid, tetrasodium salt
• • TOCOPHEROL alpha tocopherol, vitamin E
• • TRISODIUM EDTA Ethylenediaminetetraacetic acid, trisodium salt
• • Polysaccharides Propellants for sprays
• • butane
• • carbon dioxide
• • dimethyl ether
• Isobutane, 2-methylpropane
• Nitrogen
• • Propane

Opacifiers / nacreous

• • calcium sulfate
• • cellulose
• • GLYCOL PALMITATE Palmitic acid glycol esters; 2-Hydroxyethylpalmitat
• • MICA Mica (a silicate mineral)
• • PEG-2 STEARATE 2- (2-hydroxyethoxy) ethyl stearate; Esters of stearic acid and diethylene glycol (1: 1)
• • PROPYLENE GLYCOL DISTEARATE Propylene glycol distearate; Esters of stearic acid and propylene glycol (2: 1)
• • PROPYLENE GLYCOL STEARATE SE Propylene glycol stearate; Ester of stearic acid and propylene glycol (1: 1) containing sodium or potassium stearate denaturant softener
• • BUTYL STEARATE Butyl stearate, stearic acid butyl ester
• • CAMPHOR Fighter
• • CETEARYL ISONONANOATE Cetearyl isononanoate, esters of isononanoic acid and cetearyl alcohol
• • DIBUTYL SEBACATE Dibutyl sebacate, Sebacic acid dibutyl ester
• • DICAPRYLYL ETHER Dicaprylyl ether, dioctyl ether
• • DIISODECYL ADIPATE Diisodecyl adipate, adipic acid diisodecyl ester
• • ISOPROPYL CITRATE Isopropyl citrate, citric acid isopropyl ester
• • ISOPROPYL MYRISTATE Isopropyl myristate, myristic-isopropyl ester
• • ISOPROPYL PALMITATE Isopropyl palmitate, palmitic acid isopropyl ester
• • OCTYLDODECANOL 2-Octyldodecan-1-ol
• • SORBITOL Sorbitol, sorbitol, glucitol
• • TOSYLAMIDE / FORMALDEHYDE RESIN
• • toluenesulfonamide-formaldehyde resin
• • minerals
• • Sand
• • Essential trace elements: cobalt, iron, iodine, copper, manganese, molybdenum, selenium, silicon, zinc, arsenic, nickel, rubidium, tin, vanadium
• • Vitamins: Vitamin A, Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B4, Vitamin B5, Vitamin B6, Vitamin B7, Vitamin B8, Vitamin B9, Vitamin B12, Vitamin C, Vitamin D, Vitamin E, Vitamin K
• • Salt: table salt, Himalayan salt, Hawaiian salt, Dead Sea salt
• • micelles

Refatting substances:

• • SQUALANE 2,6,10,15,19,23-Hexamethyltetracosan
• • SQUALENE 2,6,10,15,19,23-Hexamethyl-2,6,10,14, 18,22-tetracosahexaen
• • STEARETH-10 Polyethylenglycolether des Stearylakohols (durchschnittlich 10 Einheiten -CH2-CH2-O-)
• • STEARYL ALCOHOL Stearylalkohol, 1-Octadecanol
• • TRIMYRISTIN Glyceryl-Trimyristat; Veresterungsprodukt von Glycerin und Myristinsäure (1:3)
• • TRIPALMITIN
• • Eucerit, Wollwachsalkohole Glyceryl-Tripalmitat; Veresterungsprodukt von Glycerin und Palmitinsäure (1:3)
• • WHEAT GERM GLYCERIDES Veresterungsprodukt von Glycerin und Fettsäuren aus Weizenkeimöl

Substances that are usually added to surfactant preparations in order to counteract their degreasing character are substances which are also called moisturizers and / or moisturizers. For this purpose, the following moisturizing substances are used. The list below is exemplary and not exhaustive. The person skilled in the art, on the basis of his general knowledge, can easily name further possible refatting substances.

• SQUALANE 2,6,10,15,19,23-hexamethyltetracosane
• SQUALENE 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene
• • STEARETH-10 polyethylene glycol ethers of stearyl alcohol (average 10 units -CH2-CH2-O-)
• • STEARYL ALCOHOL stearyl alcohol, 1-octadecanol
• TRIMYRISTINE glyceryl trimyristate; Esterification product of glycerine and myristic acid (1: 3)
• • TRIPALMITINE
• • Eucerit, wool wax alcohols glyceryl tripalmitate; Esterification product of glycerol and palmitic acid (1: 3)
• • WHEAT GERM GLYCERIDES esterification product of glycerine and fatty acids from wheat germ oil

oils:

• • BETULA ALBA BARK EXTRACT (Birke)
• • CAPRYLIC/CAPRIC TRIGLYCERIDE Veresterungsprodukt von Glycerin und Caprinsäure sowie Caprylsäure (1:3)
• • CETEARYL ALCOHOL Cetearylalkohol, Mischung aus 1-Hexadecanol (Cetylalkohol) und 1-Octadecanol (Stearylalkohol)
• • CYCLOMETHICONE Cyclomethicon; besteht aus Octamethylcyclotetrasiloxan (D4), Decamethylcyclopentasiloxan (D5) und Dodecamethylcyclohexasiloxan (D6)
• • DIBUTYL SEBACATE Dibutylsebacat, Sebacinsäuredibutylester
• • DICAPRYLYL ETHER Dicaprylylether, Dioctylether
• • DIISODECYL ADIPATE Diisodecyladipat, Adipinsäure-Diisodecylester
• • DIMETHICONE Polydimethylsiloxan
• • GLYCERYL STEARATE Glycerinstearat, Glycerinmonostearat, Stearinsäure-Glycerinester
• • ISOPROPYL MYRISTATE Isopropylmyristat, Myristinsäure-Isopropylester
• • ISOPROPYL PALMITATE Isopropylpalmitat, Palmitinsäure-Isopropylester
• • KAKAO-BUTTER
• • MACADAMIA INTEGRIFOLIA SEED OIL Macadamia; Macadamianuss, echte; Macadamianussöl
• • MACADAMIA TERNIFOLIA SEED OIL Macadamia, dreiblättrige; Macadamianussöl
• • OCTYLDODECANOL 2-Octyldodecan-l-ol
• • PARAFFIN Hartparaffin, Mikrokristallines Wachs, Ozokerit, Ceresin, Vaselin
• • PARAFFINUM LIQUIDUM Flüssiges Paraffin, Paraffinöl, Mineralöl
• • PERSEA GRATISSIMA OIL Avocado; Avocadoöl
• • SHEA-BUTTER
• • SIMMONDSIA CHINENSIS SEED OIL Jojobastrauch; Jojobaöl
• • STEARIC ACID n-Octadecansäure, Octadecansäure, Stearinsäure Duft- und/oder Aromastoffe

Oils are a collective term for different liquid fatty substances. These include, inter alia, mineral oils, silicone oils and / or oils of natural origin, such as vegetable oils and / or essential oils. These are often characterized by monounsaturated and / or polyunsaturated fatty acids. Oils of animal origin are usually referred to as fats. In addition, many oil components used in cosmetics are synthesized based on natural raw materials. Just like the lubricating substances, oil components prevent the premature drying of the skin and / or hair. In the list below, the oils are listed by example and not by definition. The person skilled in the art, on the basis of his general knowledge, can easily name further possible oils.

• • BETULA ALBA BARK EXTRACT (birch)
• • CAPRYLIC / CAPRIC TRIGLYCERIDE esterification product of glycerol and capric acid as well as caprylic acid (1: 3)
• • CETEARYL ALCOHOL Cetearyl alcohol, mixture of 1-hexadecanol (cetyl alcohol) and 1-octadecanol (stearyl alcohol)
• • CYCLOMETHICONE cyclomethicone; Composed of octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5) and dodecamethylcyclohexasiloxane (D6)
• • DIBUTYL SEBACATE dibutyl sebacate, dibasic sebacate
• • DICAPRYLYL ETHER Dicaprylyl ether, dioctyl ether
• • DIISODECYL ADIPATE Diisodecyl adipate, adipic acid diisodecyl ester
• • DIMETHICONE polydimethylsiloxane
• • GLYCERYL STEARATE Glycerine stearate, glycerol monostearate, stearic acid glycerol ester
• ISOPROPYL MYRISTATE isopropyl myristate, myristic isopropyl ester
• • ISOPROPYL PALMITATE Isopropyl palmitate, palmitic acid isopropyl ester
• • COCOA BUTTER
• • MACADAMIA INTEGRIFOLIA SEED OIL Macadamia; Macadamia nut, genuine; macadamia nut oil
• • MACADAMIA TERNIFOLIA SEED OIL Macadamia, trifoliate; macadamia nut oil
• OCTYLDODECANOL 2-octyldodecan-1-ol
• • PARAFFIN hard paraffin, microcrystalline wax, ozokerite, ceresin, vaseline
• • PARAFFINUM LIQUIDUM Liquid paraffin, paraffin oil, mineral oil
• • PERSEA GRATISSIMA OIL avocado; avocado oil
• • SHEA BUTTER
• • SIMMONDSIA CHINENSIS SEED OIL Jojoba smoke; jojoba oil
• • STEARIC ACID n-octadecanoic acid, octadecanoic acid, stearic acid fragrances and / or flavorings

Essential oils, flavors, fragrances and perfumes:

Essential oils are volatile, intense-smelling mixtures of oily consistency that are sparingly soluble in water. They are usually obtained from vegetable raw materials by steam distillation. They can also be obtained by synthesis, extraction or by squeezing. Herbal substances such as menthol, cineole, vanillin and / or thymol are also referred to as essential oils. In medicine, they are used depending on the oil for the treatment of numerous complaints, u. a. Muscle and joint pain, infectious diseases, colds and discomfort in the gastrointestinal tract. Furthermore, they are used in cosmetics especially for perfuming.

Flavors are products that are added to foods, for example, to give them a special smell and / or taste. An aroma can consist of numerous flavors, aroma extracts, thermally derived reaction aromas, smoke flavors and / or aroma precursors. Most flavors are used industrially in food production, and some flavors are also available in retail stores. Flavorings are chemically defined substances with flavor Properties (aroma properties), which are used for the production of aromas. There are different natural, nature-identical and / or artificial flavorings.

On the one hand, fragrances used in cosmetics are organic compounds from the animal and plant kingdoms. Furthermore, fragrances are compounds that can be synthesized. The purpose of the fragrances in cosmetic products is to mask the odor of a drug and continue to trigger pleasant sensations in the consumer. Perfumes in the narrower sense are fragrances and fragrance mixtures that are supposed to change or mask the body odor.

The following list of essential oils, flavors, fragrances and perfumes is exemplary and not fully listed. The person skilled in the art, on the basis of his general knowledge, can easily name further possible essential oils, flavors and / or fragrances and / or perfume.

Essential oils:

• • CAMPHOR Fighter
• • CINNAMOMUM ZEYLANICUM LEAF OIL Cinnamomum verum; Zimtlorbeerbaum
• • CITRUS LIMON PEEL OIL Lemon Tree; lemon
• • EUCALYPTOL eucalyptol; 3,3-trimethyl-2-oxabicyclo [2.2.2] octane, 1,8-cineole
• • JASMINUM OFFICINAL FLOWER EXTRACT jasmine
• • LAVANDULA ANGUSTIFOLIA OIL Lavender, real
• • ALMOND OIL (Sweet Almond oil)
• • MENTHOL Menthol; 5-methyl-2- (1-methylethyl) cyclohexanol
• • PINUS SYLVESTRIS LEAF OIL Pine, mean
• • VANILLIN vanillin

flavorings

• • AROMA Flavoring, Flavor Blend
• • MENTHOL Menthol; 5-methyl-2- (1-methylethyl) cyclohexanol
• • VANILLIN vanillin

Perfumes and / or fragrances

• • ANISE ALCOHOL anisalcohol; Anisyl alcohol, 4-methoxybenzyl alcohol
• • BENZYL ALCOHOL benzyl alcohol; phenylmethanol
• • CINNAMOMUM ZEYLANICUM LEAF OIL cinnamon; Zimtlorbeerbaum
• • CITRUS LIMON PEEL OIL Lemon Tree; lemon
• • EUCALYPTOL eucalyptol; 3,3-trimethyl-2-oxabicyclo [2.2.2] octane, 1,8-cineole
• • JASMINUM OFFICINAL FLOWER EXTRACT jasmine
• • METHYL PHENYLBUTANOL 2-methyl-4-phenyl-butan-2-ol
• • OCTYLDODECANOL 2-Octyldodecan-1-ol
• • PERFUME

Perfumes, fragrances and perfume mixtures

• • PINK INDICA FLOWER EXTRACT tea rose
• • PINK CENTIFOLIA Rose water
• • LIMONENE Limonene, carvene, p-mentha-1,8-diene, 1-methyl-4-prop-1-en-2-ylcyclohexene, 1-methyl-4-isopropenyl-1-cyclohexene

Moisturizer / moisturizer:

• • ALOE BARBADENSIS LEAF JUICE Aloe vera; Gel / Juice
• • ALOE BARBADENSIS LEAF JUICE POWDER Aloe vera
• • collages
• • GLYCERINE glycerin
• • HYALURONIC ACID hyaluronic acid
• • LACTIC ACID Lactic acid; 2-hydroxypropionic acid, 2-hydroxypropanoic acid
• • SODIUM HYALURONATES Sodium hyaluronate (sodium salt of hyaluronic acid)
• • SODIUM LACTATE Sodium lactate (sodium salt of lactic acid)
• • UREA urea
• • ALGAE (algae)
• • ECHINACEA PURPUREA EXTRACT

Active ingredients for skin care:

• • ALLANTOIN Glyoxylic acid diureide, 5-ureidohydantoin, N- (2,5-dioxo-4-imidazolidinyl) urea
• • ALOE BARBADENSIS LEAF JUICE Aloe vera; Gel / Juice
• • ASCORBIC ACID Vitamin C, ascorbic acid
• • BISABOLOL alpha-bisabolol, ®-6-methyl-2- (®-4-methylcyclohex-3-enyl) hept-5-en-2-ol
• • C12-15 ALKYL BENZOATE Esters of benzoic acid and fatty alcohols of chain length C12 to C15
• • CAPRYLIC / CAPRIC TRIGLYCERIDE Esterification product of glycerol with capric acid and caprylic acid (1: 3)
• • CHAMOMILLA RECUTITA FLOWER EXTRACT Chamomile, real
• • DECYL OLEATE oleate; Esterification product of oleic acid with decyl alcohol
• • DIETHYLHEXYL SYRINGYLIDENE MONALATE [(4-Hydroxy-3,5-dimethoxyphenyl) methylene] -propanedioic acid, bis (2-ethylhexyl) ester
• • ETHYLHEXYL COCOATE Esterification product of 2-ethylhexanol and coconut fatty acids
• • ETHYLHEXYLSTEARATE Stearic acid 2-ethylhexyl
• • ETHYLHEXYLGLYCERINE Ethylhexylglycerin; 3- (2-ethylhexyloxy) -1,2-propanediol
• • FAGUS SILVATICA (beech)
• • HYALURONIC ACID hyaluronic acid
• • Niacinamide Niacinamide, 3-pyridinecarboxamide, pyridine-3-carboxylic acid amide, nicotinic acid amide, nicotinamide
• • PANTHENOL Dexpanthenol, provitamin B5
• • PERSEA GRATISSIMA OIL Avocado; avocado oil
• • PPG-15 STEARYL ETHER Stearyl alcohol, etherified with polypropylene glycol (average 15 units of propylene glycol)
• • PROPYLHEPTYL CAPRYLATE Esterification product of 2-propylheptanol with caprylic acid
• • SIMMONDSIA CHINENSIS SEED OIL Jojoba; jojoba oil
• • SODIUM HYALURONATES Sodium hyaluronate (sodium salt of hyaluronic acid)
• • STEARYL DIMETHICONE Poly (dimethyl-methylstearyl) siloxane
• • SUCROSE LAURATE Esterification product of lauric acid with sucrose (cane sugar)
• • TOCOPHEROL alpha-tocopherol, vitamin E
• • UBIQUINONE Q10, Coenzyme Q10; Coenzyme Q10
• • HELIANTHUS ANNUUS HYBRID OIL
• • ECHIUM PLANTAGINEUM SEED OIL
• • CARDIOSPERMUM HALICACABUM FLOWER / LEAF / VINE EXTRACT
• • RUTIN
• • ARGININE

Deodorising agents:

• • FARNESOL Farnesol, 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
• • PERFUME Perfume; Perfumes and perfume mixtures
• • TRICLOSAN Triclosan, 5-chloro-2- (2,4-dichlorophenoxy) phenol
• • TRIETHYL CITRATE triethylcitrate; Citric acid triethyl
• • ZINC LACTATE Zinc lactate (zinc salt of lactic acid)
• • ZINC RICINOLEATE ricinoleate

Solvent:

• • 1,2-HEXANEDIOL 1,2-hexanediol; 1,2-dihydroxyhexane
• • ACETONE Acetone, propanone
• • ALCOHOL Alcohol, ethanol, ethanol, ethyl alcohol
• • ALCOHOL DENAT denatured alcohol, denatured alcohol
• • AQUA water
• • BUTYL ACETATE Butyl acetate, butyl acetate
• • BUTYLENE GLYCOL 1,3-butanediol, butylene glycol
• • CYCLOPENTASILOXANE decamethylcyclopentasiloxane
• • ETHYL ACETATE Ethyl acetate, ethyl acetate
• • GLYCERINE Glycerol, glycerol, 1,2,3-propanetriol
• • GLYCOL Glycol, ethylene glycol, ethylene glycol
• • ISOPROPYL ALCOHOL Isopropyl alcohol, isopropanol, 2-propanol
• • METHYLPROPANEDIOL 2-methyl-1,3-propanediol
• • PROPYLENE GLYCOL 1,2-propanediol, propylene glycol
• • ECHIUM PLANTAGINEUM SEED OIL

film formers:

• • ACRYLATES COPOLYMER Polymer of methacrylic acid, ethyl acrylate and methyl methacrylate
• • ACRYLATES / HYDROXYESTERS ACRYLATES COPOLYMER Copolymer of acrylic acid / methacrylic acid and its esters and hydroxyacrylates
• • ACRYLATES / STEARETH-20 METHACRYLATE CROSSPOLYMER Copolymer of steareth-20-methacrylate and acrylic acid / methacrylic acid and their esters cross-linked with pentaerythritol allyl ether. Steareth-20-methacrylate is an ester of methacrylic acid with polyethylene glycol (avg. 20 units -CH ₂ -CH ₂ -O-)
• • DIBUTYL SEBACATE Dibutyl sebacate, Sebacic acid dibutyl ester
• • NITROCELLULOSE Nitrocellulose, cellulose nitrate, gun cotton
• • PVP polyvinylpyrrolidone
• • SODIUM CARBOMER Polyacrylic acid (sodium salts)
• • TOSYLAMIDE / FORMALDEHYDE RESIN Toluene sulfonamide-formaldehyde resin
• • PHTHALIC ANHYDRIDE / TRIMELLITIC ANHYDRIDE / GLYCOLS COPOLYMER

gelling agent:

• • AGAR Agar, agar-agar
• • ALGIN Sodium alginate (sodium salt of alginic acid)
• • ALGINIC ACID alginic acid
• • CARBOMER polyacrylic acid
• • CARRAGEENAN Moss, Irish; carrageenan
• • HECTORITE Hectorite (clay mineral)
• • HYDROXYETHYL CELLULOSE hydroxyethyl
• • HYDROXYPROPYLCELLULOSE hydroxypropyl
• • POLYVINYL ALCOHOL polyvinyl alcohol
• • PVP polyvinylpyrrolidone
• • SODIUM CARBOMER Polyacrylic acid (sodium salts)
• • STEARAL KONG HECTORITE

Tanning agents, tanning agents and / or tannin extracts:

There is a distinction between tannins, tannins and / or tannin extracts. Tannins are chemicals used to tan animal skins. By treating with tannins the animal skins are converted into leather, which among other things prevents the rot. Furthermore, there are naturally occurring, ie natural, as well as artificially produced, ie synthetic tannins. Tanning agents are plant parts and / or mixtures containing one and / or more tannins. The terms tanning agent and / or tanning agent are often used as synonyms. A tannin extract is an extract of a tanning agent. After extraction, the tanning agent is in a higher concentration, without any interfering constituents of the starting material. Vegetable tannins, also called tannins, are also used in medicine. Furthermore, tannins are known as taste components of wine and tea.

Examples of suitable tannins:

• • Gallotannins
• • catechols
• • Catechin
• • mineral tannins,
• • aldehydes,
• • aliphatic paraffin sulphochlorides,
• • Synthetic tanning agents (Syntans) based on phenol derivatives,
• • polymer tanning agents (resin tanning agents)

Bitter substances:

Bittern refers to all chemical compounds that have a bitter taste. They are not a chemically unified group, but are characterized only by the fact that they taste bitter. The following bitter substances are only exemplary and not fully listed. The person skilled in the art, on the basis of his general knowledge, can easily name other possible bitter substances.

Examples of suitable bitter substances:

• • Lactucopikrin occurs in the common chicory and all lattices.
• • Cynarin is found in artichokes.
• • Glucosinolates occur in rapeseed oil.
• • Lactucin occurs in iceberg lettuce.
• • premarubiin and marrubiin
• • Naringin in grapefruit and pomelos

Color pigments:

Dyes, colored pigments, white pigments, fluorescent pigments and phosphorescent pigments (phosphorus) can be added in many different ways to the topical preparations according to the invention. Preference is given to chalk, talc, montmorillonite, clay minerals, papers, paper-like materials and / or titanium dioxide, also black titanium dioxide.

Plant extracts:

Plant extracts are extracts of plants used in cosmetics. The following list of plant extracts is exemplary and not exhaustive. The person skilled in the art can easily name further possible plant extracts.

Examples of suitable plant extracts:

• • African Copal bark CO ₂ -sextract
• • Angelica root CO ₂ -sextract
• • Antimicrobial blend
• • Arnica flowers CO ₂ -to extract, 4% sesquiterpene lactones
• • Beard lichen CO ₂ -to extract, water-dispersible, 4% usnic acids
• • Borage-rich CO ₂ -to extract
• • Butter CO ₂ -sextract, Dest. Type
• • Butter CO ₂ -sextract, Krist. Type
• • Chili CO ₂ -to extract, 10% capsaicinoids
• • Chili CO ₂ -to extract, 5% capsaicinoids
• • Curcuma Xanthorrhiza CO ₂ -sextract
• • Dillseed CO ₂ -sextract, carvone type
• • Dillseed CO ₂ -sextract, dillapiol type
• • Peanut CO ₂ -sextract
• • Fennel CO ₂ -sextract, Bitter type
• • Flavoxan 14, rosemary antioxidant formulation

Foam inhibitors and defoamers:

• • Silicone oils with silica particles
• • mono and diglycerides of fatty acids
• Polydimethylsiloxane (Simethicone®, E900)
• • Tri-n-butyl phosphate
• • tri-isobutyl phosphate
• • Thermooxidized soybean oil esterified with MDG (mono- and diglycerides)

• - der amerikanischen Patentanmeldung US 2012/0258150 A1 , Seiten 4 bis 6, TABLE 1, Seite 7, Absatz [0071], bis Seite 9, Absatz [00 88] Ende,
• - der deutschen Patentanmeldung DE 10 2012 214 622 A1 , Seite 4, Absatz [0016], bis Seite 16, Absatz [0039], sowie aus
• - dem europäischen Patent EP 1 235 546 B1 , Seite 7, Absatz [0016], bis Seite 9, Absatz [0025] Ende, Seite 9, Absätze [0027] bis [0030], Seite 9, Absatz [0033], bis Seite 14, [0055],

bekannt.Examples of further suitable ingredients (E) for the topical preparations according to the invention are from

• - the American patent application US 2012/0258150 A1 , Pages 4 to 6, TABLE 1, page 7, paragraph [0071], to page 9, paragraph [00 88] end,
• - the German patent application DE 10 2012 214 622 A1 , Page 4, paragraph [0016], to page 16, paragraph [0039], as well as from
• - the European patent EP 1 235 546 B1 , Page 7, paragraph [0016], to page 9, paragraph [0025] end, page 9, paragraphs [0027] to [0030], page 9, paragraph [0033], to page 14, [0055],

known.

The topical preparations according to the invention may contain customary and known ionic and / or nonionic surfactants as ingredients (E) (cf., Rompp Lexikon Lacke and Druckfarben, Georg Thieme Verlag, Stuttgart, 1998, keyword "surfactants"). However, it is a particular advantage of the topical preparations according to the invention that in the vast majority of cases they manage without surfactants, in particular without ionic surfactants.

The proportion of the ingredients (E) in the topical preparations according to the invention can vary very widely and are thus perfectly adapted to the respective intended use. Preferably, a given topical preparation contains, based on its total amount, from 0.01% to 70%, preferably from 0.01% to 60%, and most preferably 0.01%, by weight % By weight of ingredients (E).

The topical preparations according to the invention preferably have a pH of between 3 and 7, preferably between 4.5 and 6.5 and in particular between 5 and 5.5, in particular in order not to damage the acidity of the skin. In special cases, the topical preparations according to the invention may also have a pH of> 7.

The topical preparations according to the invention are preferably in the form of powders, solids, granules, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, and coatings on and components of toilet utensils, textile fabrics, face masks, envelopes, sanitary napkins , Tampons, gauze, plasters, medical devices and release materials. This list is only an example and not exhaustive and there are, in particular for special applications, other dosage forms into consideration.

The topical preparations according to the invention are preferably prepared by the process according to the invention. In this case, at least one type of particles (A) with at least one type of particles (B) and / or at least one type of particles (C) are mixed together and the resulting mixture homogenized. Subsequently, the resulting homogenized mixture (AB), (AC) or (ABC) is preferably processed into powders, solids, granules, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enema, suppositories or foams and / or applied to and / or in textile fabrics, face masks, gauze, envelopes, bandages, tampons, plasters, medical devices and / or release materials.

In a preferred embodiment, at least one type of particle (A) is associated with at least one type of particle (B) and / or at least one type of particle (C), at least one polyoxometalate (D) and / or at least one ingredient (E) and homogenize the resulting mixture (ABC), (ABD), (ABE), (ACD), (ACE), (ADE), (ABCD), (ABCE) or (ABCDE), followed by the homogenized mixture as described above , is processed.

If aqueous topical preparations according to the invention are prepared by the process according to the invention, it proves to be an advantage if carbon dioxide-containing water is used, because in this way the carbon particles (A) are better wetted. The carbon dioxide can be present dissolved in water, which is optionally carried out at overpressure, or blown through the water or bubbled.

The process according to the invention uses the customary and known systems, aggregates, apparatuses, metering techniques and measuring techniques commonly used in the fields of the production of cosmetics, care products, pharmaceuticals and medical aids and equipment.

The topical preparations according to the invention are versatile in use. Thus, they can be used as cosmetics, care products and products for saunas and steam baths and for the care of skin, in particular overlaps on chest, abdomen and groin, mucous membranes, eyes, ears, mouth, lips, fingernails, toenails, cornea, warts and scars Excretions of noxa, drugs, toxins, medicines, acids, bases and odorants through the skin, lesions, itching, intertrigo, burning, infections and redness, in cancer therapy, chemotherapy, chondrocalcinosis, skin diseases such as: psoriasis, atopic dermatitis, acne, eczema , atrophic eczema, warts, rosacea, herpes, shingles, measles, mumps, rubella, chickenpox, hand-foot-and-mouth disease, hand and foot syndrome, for preventative protection, to aid in the healing of existing infections, wounds or burns , are used in the decorative cosmetics, in the cosmetic facial care, in the hair care and in the personal care of humans and animals

Preferably, the products according to the invention in the dosage form of decorative cosmetics, care products, products for saunas and steam baths, powders, solids, granules, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, suppositories , Foams and toilet utensils, textile fabrics, face masks, envelopes, sanitary napkins, tampons, gauze, plasters, medical devices and release materials. Again, this list is not exhaustive, but exemplary. In particular, in special cases, other product forms may also be used.

• • zur Hygiene
• • zur Desinfektion
• • bei Infektionsgefahr
• • bei Pilzinfektion, auch im Genitalbereich
• • bei Bindehautentzündungen
• • beim Gerstenkorn
• • bei trockenen Augen
• • bei Hautausschlag
• • bei Juckreiz, wie z.B. Neurodermitis, Schuppenflächte, Gürtelrose usw.
• • zur Geruchsbeseitigung (wie bspw. Schweiß)
• • zur Belebung der Haut
• • zur Beruhigung der Haut
• • zur Kühlung der Haut
• • bei geröteter, juckender, brennender oder geschwollener Haut
• • bei rissiger, spröder Haut (Schrunden)
• • zum Infektionsschutz vor Bakterien, Viren, Pilzen etc
• • nach jeder Rasur
• • nach Insektenstichen
• • vorbeugend
• • zur Unterstützung des Heilungsprozesses bei bestehenden Infektionen, Wunden oder Verbrennungen
• • für Schleimhäute, Augen, Ohren und Mund

For example, the products of the invention in the appropriate dosage form

• • for hygiene
• • for disinfection
• • at risk of infection
• • in fungal infections, even in the genital area
• • in conjunctivitis
• • with barley grain
• • with dry eyes
• • with rash
• • itching, such as eczema, scale, shingles, etc.
• • for odor removal (such as sweat)
• • to invigorate the skin
• • to soothe the skin
• • to cool the skin
• • with reddened, itchy, burning or swollen skin
• • with cracked, rough skin (Schrunden)
• • for infection protection against bacteria, viruses, fungi etc
• • after every shave
• • after insect bites
• • preventive
• • to support the healing process of existing infections, wounds or burns
• • for mucous membranes, eyes, ears and mouth

As a decorative cosmetics

• • as cover products
• • as eye make-up products (other)
• • as eyeliner
• • as a kohl pencil
• • as body colors
• • as eye shadow
• • as lip make-up products (other)
• • as a lipstick sealer
• • as lipsticks
• • as a make-up
• • as a make-up remover
• • as a nail bleach
• • as a cuticle care / remover
• • as a nail hardener
• • as nail glue remover
• • as a nail polish remover
• • as a nail polish thinner
• • as nail polish / nail make-up
• • as a nail modeling agent
• • as mascara
• • as after- and pre-shave products
• • as eye care products
• • as face masks
• • as facial care products
• • as lip care products
• • as exfoliating products (chemical)
• • as exfoliating products (mechanical)
• • as exfoliating products (enzymatic)
• As a shaving agent (wet and dry shave)
• • as rinse-off products

For hair care

• • as anti-dandruff products
• • as a bleaching agent for body hair
• • as permanent wave products
• As a hair bleaching / decolorizing agent
• • as hair colors (not oxidative)
• • as hair colors (oxidative)
• • as a hair conditioner (care)
• • as a hairstylist (styling)
• • hair straightener
• • as hair cleansing and hair care products (other)
• • as hairstyling products (other)
• • as products against hair loss
• • as products for the care of scalp and hair roots
• • as shampoos
• • as sunscreen products for the hair

For body care

• • as antiperspirants
• • as bath and shower products, as well as a moor bath
• • as a bleaching agent for body hair
• • as depilation products
• • as deodorants (deodorants)
• • as fragrance products (other)
• • as epilation products
• • as foot care products
• • as hand care products
• • as a skin bleaching agent
• • as skin care products (other)
• • as skin cleansing products (other)
• • as personal care products
• • as personal care products
• • as nail care products
• • as perfumes and perfume waters
• • as exfoliating products (chemical)
• • as exfoliating products (mechanical)
• • as pre and aftersun products
• As a shaving agent (wet and dry shave)
• • as soaps and syndets
• • as a self-tanning agent
• • as massage oil
• • as an alternative to perfume
• • as a self-tanning agent
• • as sunscreen products
• • as sunscreen products for the hair

For dental and oral care

• • Mundsprays
• • Mundwässer
• • Zahn-Bleichmittel
• • Zahncremes

verwendet werden.

• • mouth sprays
• • mouthwashes
• • tooth bleach
• • toothpastes

be used.

A further field of application according to the invention are applications in the case of skin problems such as oxidative stress caused by radicals. Furthermore, different creams can be produced, which are enriched during the day with, for example, a UV filter and at night with lipids. In addition, a regeneration balm can be made. In addition, mucosal care and / or scalp nonwoven can be made. Particular preference is given to using sauna creams. Furthermore, creams are particularly preferred that can be used in chemotherapy. Furthermore, the products according to the invention do not trigger allergies and can even reduce existing allergies. In addition, the skin can be rejuvenated by the products according to the invention or the aging process of the skin can be slowed down.

In the following the invention will be explained in more detail by means of examples. The examples are not limiting but are intended to make the feasibility of the invention believable.

Examples

example 1

Preparation and use of an ointment for the absorption and / or decomposition of chemotherapeutic agents deposited via the skin

• - 1 Gewichtsteil molekulardisperser Wolframatophosphorsäure-Hydrat {H₃[P(W₃O₁₀)₄]0· xH₂O, CAS-Nr. 1343-93-7 (D),
• - 0,5 Gewichtsteile Dikaliumhydrogenphosphat als Puffer (D) und
• - 0,05 Gewichtsteile Simethicone® E900 Schauminhibitor (D)

in 52,45 Gewichtsteilen Wasser (E) unter sterilen Bedingungen und Durchperlen von Kohlendioxid dispergierte. Die resultierende pastöse Salbe wurde unter leichtem Rühren und Unterdruck entgast und in sterile Spender abgefüllt.An ointment for oncological application was prepared by

• 1 part by weight of molecularly dispersed tungstophosphoric acid hydrate {H ₃ [P (W ₃ O ₁₀ ) ₄ ] 0 .xH ₂ O, CAS no. 1343-93-7 (D),
• - 0.5 parts by weight of dipotassium hydrogen phosphate as buffer (D) and
• - 0.05 parts by weight of Simethicone® E900 foam inhibitor (D)

in 52.45 parts by weight of water (E) under sterile conditions and bubbled with carbon dioxide. The resulting pasty ointment was degassed with gentle stirring and reduced pressure and filled into sterile dispensers.

In cancer patients who had to undergo chemotherapy, very strong drugs were absorbed into the body. Some of these drugs and their metabolites were excreted. This happened, among other things, via the skin. This meant that not only the skin of the cancer patients, but also their environment and the nursing staff were damaged.

• Chemotherapeutika auf der Basis von Platin:
  • Carboplatin
  • Cisplatin
• Alkylierende Chemotherapeutika auf der Basis von Senfgas:
• Nitrosoharnstoffderivate:
  • Carmustin (BCNU)
• Antimetabolite:
  • Methotrexat
• Purinanaloge Metabolite
• Pyrimidinanaloge Antimetabolite:
  • Fluorouracil (5-FU)
  • Gemcitabin
• Hormonale antineoplastische Verbindungen:
  • Goselerin
  • Leuprolid
  • Temoxifen
• Natürliche antineoplastische Verbindungen:
  • Taxane
  • Doclitaxel
  • Paclitaxel
• Leukine:
  • Aldesleukin
  • Interleukin-2
  • Etoposid (VP-16)
  • Interferon alfa
  • Tretinoin (ATRA)
• Antibiotische natürliche neoplastische Verbindungen:
  • Bleomycin
  • Dactinomycin
  • Daunarubicin
  • Doxorubicin
  • Mitomycin
• Vinca alkaloid natural antineoplasics:
  • Vinblastin
  • Vincristin
• Weitere Medikamente:
  • Daunarubicin HCl
  • Docetaxel
  • Doxorubicin HCl
  • Epoetin alpha
  • Ganciclovir Natrium
  • Gentamicinsulfat
  • Interferon alpha
  • Leuprolidacetat
  • Meperidin HCl (Phetidin)
  • Methadon HCl
  • Ranitidin HCl
  • Vinblastinsulfat
  • Zidovudin (AZT)
  • Fluorouracil + Epinephrin + Bovinecollagen.

wurde mit der Salbe behandelt. Nach einer Einwirkung der Salbe von jeweils 10 Stunden, wurde sie abgewaschen. Es zeigte sich, dass die Haut der Krebspatienten nicht gereizt oder geschädigt worden war und dass keine Medikamente und Metaboliten mehr auf der Haut nachgewiesen werden konnten.The skin of cancer patients treated with at least one of the following chemotherapeutic agents:

• Chemotherapeutic agents based on platinum:
  • carboplatin
  • cisplatin
• Alkylating chemotherapeutic agents based on mustard gas:
• nitrosourea derivatives:
  • Carmustine (BCNU)
• Antimetabolites:
  • methotrexate
• Purine-analogous metabolites
• Pyrimidine analog antimetabolites:
  • Fluorouracil (5-FU)
  • gemcitabine
• Hormonal antineoplastic compounds:
  • Goselerin
  • leuprolide
  • Temoxifen
• Natural antineoplastic compounds:
  • taxanes
  • Doclitaxel
  • paclitaxel
• Leukine:
  • aldesleukin
  • Interleukin-2
  • Etoposide (VP-16)
  • Interferon alfa
  • Tretinoin (ATRA)
• Antibiotic natural neoplastic compounds:
  • bleomycin
  • dactinomycin
  • Daunarubicin
  • doxorubicin
  • mitomycin
• Vinca alkaloid natural antineoplasics:
  • vinblastine
  • vincristine
• Other medicines:
  • Daunarubicin HCl
  • docetaxel
  • Doxorubicin HCl
  • Epoetin alpha
  • Ganciclovir sodium
  • Gentamicin sulfate
  • Interferon alpha
  • leuprolide acetate
  • Meperidine HCl (Phetidine)
  • Methadone HCl
  • Ranitidine HCl
  • vinblastine
  • Zidovudine (AZT)
  • Fluorouracil + epinephrine + bovine collagen.

was treated with the ointment. After an ointment action of 10 hours each, it was washed off. It turned out that the skin of cancer patients had not been irritated or damaged and that no more drugs and metabolites could be detected on the skin.

Example 2

The production and application of a sauna paste for purification of the body

• - 100 Gewichtsteile von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 50 Gewichtsteile von Himalayasalz (D) einer mittleren Teilchengröße d₅₀ von 100 µm und
• - 20 Gewichtsteile Bienenwachs (B) einer mittleren Teilchengröße von 100 µm

unter sterilen Bedingungen bei 10 °C in einer Kugelmühle innig vermahlen. Das resultierende Pulver wurde von den Mahlkugeln abgetrennt.For the preparation of the sauna paste were initially

• 100 parts by weight of particles (A) of fumed carbon having an average particle size d ₅₀ of 650 ± 50 nm,
• - 50 parts by weight of Himalayasalz (D) of an average particle size d ₅₀ of 100 microns and
• 20 parts by weight of beeswax (B) having an average particle size of 100 μm

Milled intimately under sterile conditions at 10 ° C in a ball mill. The resulting powder was separated from the grinding balls.

• - 300 Gewichtsteilen Eucerit (B),
• - 300 Gewichtsteile Bienenwachs (B) einer mittleren Teilchengröße von 100 µm und
• - 100 Gewichtsteile Wasser (E)

hergestellt. Die Emulsion war in der Lage größere Mengen an Wasser aufzunehmen.It was under sterile conditions, a water-in-oil emulsion

• - 300 parts by weight of Eucerit (B),
• 300 parts by weight of beeswax (B) having an average particle size of 100 μm and
• - 100 parts by weight of water (E)

manufactured. The emulsion was able to absorb larger amounts of water.

The powder was now incorporated into the water-in-oil emulsion so that it was uniformly dispersed therein.

For use, the sauna paste is massaged before, during and / or after a sauna session in the dry or sweaty skin and allowed to act on the skin during the resting phase. The paste quickly absorbed sweat and other body deposits. Before the next sauna session the sauna paste could be washed off. The process could be repeated several times during a sauna visit and caused a lasting purification of the body, and the skin seemed rejuvenated and wrinkle-free and was odor-neutralized.

Example 3

The preparation and application of a peeling paste

• - 50 Gewichtsteile von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 50 Gewichtsteile von Himalayasalz (E) einer mittleren Teilchengröße d₅₀ von 100 µm
• - 50 Gewichtsteile Koridonkristalle einer mittleren Teilchengröße d₅₀ von 50 µm

unter sterilen Bedingungen bei 10 °C in einer Kugelmühle innig vermahlen. Das resultierende Pulver wurde von den Mahlkugeln abgetrennt.To prepare the exfoliating paste were

• 50 parts by weight of particles (A) of pyrogenic carbon having an average particle size d ₅₀ of 650 ± 50 nm,
• - 50 parts by weight of Himalayasalz (E) of an average particle size d ₅₀ of 100 microns
• - 50 parts by weight of Koridonkristalle a mean particle size d ₅₀ of 50 microns

Milled intimately under sterile conditions at 10 ° C in a ball mill. The resulting powder was separated from the grinding balls.

• - 50 Gewichtsteilen Eucerit (B),
• - 50 Gewichtsteile Bienenwachs (B) einer mittleren Teilchengröße von 100 µm und
• - 20 Gewichtsteile Wasser (E)

hergestellt. Die Emulsion war in der Lage größere Mengen an Wasser aufzunehmen.It became a sterile water-in-oil emulsion

• - 50 parts by weight of Eucerit (B),
• 50 parts by weight of beeswax (B) having an average particle size of 100 μm and
• - 20 parts by weight of water (E)

manufactured. The emulsion was able to absorb larger amounts of water.

The powder was now incorporated into the water-in-oil emulsion so that it was uniformly dispersed therein.

The resulting exfoliating paste was massaged into the facial skin and into the décolleté and allowed to act for 30 minutes. Subsequently, the peeling paste was washed off with a lukewarm cleaning solution. The soothing effect of the peeling was clearly visible. The skin looked fresher and smoother after exfoliation. The particles (A) also caused a rapid uptake of waste products of the skin.

Example 4

The production and application of a non-greasy moisturizing and cleansing cream

• - 5 Gewichtsteile von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 10 Gewichtsteile nanokristalliner Cellulose (CNC) (C) einer mittleren Teilchengröße d₅₀ von 650 ± 100 nm,
• - 5 Gewichtsteile beta-Glucan (D) und
• - 10 Gewichtsteile Harnstoff (D)

in 150 Gewichtsteilen Wasser (E) dispergierte. Dabei bildet sich ein leicht zu verreibendes Gel.A fat-free moisturizing and cleansing cream was prepared by adding

• 5 parts by weight of particles (A) of pyrogenic carbon of an average particle size d ₅₀ of 650 ± 50 nm,
• 10 parts by weight of nanocrystalline cellulose (CNC) (C) having an average particle size d ₅₀ of 650 ± 100 nm,
• - 5 parts by weight of beta-glucan (D) and
• - 10 parts by weight of urea (D)

in 150 parts by weight of water (E) dispersed. This forms an easy-to-rub gel.

The gel was quickly absorbed by the skin and kept the skin permanently moist. The particles (A) of fumed carbon caused no discoloration of the skin because of their low dosage.

Example 5

The production of a shower gel for the cleaning and regeneration of stressed skin

It is known that in heavy smokers the skin is poorly supplied with blood and therefore looks gray. In addition, the skin is contaminated by excreta due to smoke.

• - 10 Gewichtsteilen von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 10 Gewichtsteilen nanokristalliner Cellulose (CNC) (C) einer mittleren Teilchengröße d₅₀ von 650 ± 100 nm,
• - 5 Gewichtsteilen beta-Glucan (D) und
• - 10 Gewichtsteilen Harnstoff (D),
• - 40 Gewichtsteilen Cerabellina (B) einer mittleren Teilchengröße d₅₀ von 50 µm,
• - 40 Gewichtsteilen Eucerit (B),
• - 0,5 Gewichtsteilen Pflanzenfarbstoffen und Farbpigmenten (D),
• - 0,5 Gewichtsteilen natürlicher Duftstoffen (D)
• - 10 Gewichtsteilen Bentonit (D),
• - 0,5 Gewichtsteilen eines Gemischs aus verschiedenen Vitaminen und Spurenelementen und
• - 250 Gewichtsteilen Wasser

hergestellt. Der pyrogene Kohlenstoff bewirkte eine rasche Aufnahme und den Abtransport von Schadstoffen aus der Haut. Die Nanocellulose besaß zusammen mit Cerabellina und Eucerit eine grenzflächenaktive Wirkung, sodass sich bei der Anwendung Schaum bildete. Das hautgängige beta-Glucan und die Vitamine und Spurenelemente trugen zur Ernährung und Regeneration der Haut bei. Cerabellina und Eucerit hatten eine einfettende Wirkung. Die Pflanzenfarbstoffe und Farbpigmente dienten der Tönung der Haut. Die Bentonit-Partikel hatten einen Peeling-Effekt. Die Duftstoffe überdeckten nachhaltig den typischen Rauchergeruch und der Harnstoff hielt die Haut länger feucht.For cleaning and better blood circulation of the skin was therefore a shower gel

• 10 parts by weight of particles (A) of pyrogenic carbon of an average particle size d ₅₀ of 650 ± 50 nm,
• 10 parts by weight of nanocrystalline cellulose (CNC) (C) having an average particle size d ₅₀ of 650 ± 100 nm,
• - 5 parts by weight of beta-glucan (D) and
• 10 parts by weight of urea (D),
• 40 parts by weight of Cerabellina (B) having an average particle size d ₅₀ of 50 μm,
• - 40 parts by weight of Eucerit (B),
• - 0.5 parts by weight of vegetable dyes and color pigments (D),
• - 0.5 parts by weight of natural fragrances (D)
• - 10 parts by weight of bentonite (D),
• - 0,5 parts by weight of a mixture of different vitamins and trace elements and
• - 250 parts by weight of water

manufactured. The pyrogenic carbon caused a rapid uptake and the removal of pollutants from the skin. The nanocellulose, along with Cerabellina and Eucerit, had a surfactant effect, causing foam to form during use. The skin-friendly beta-glucan and the vitamins and trace elements contributed to the nutrition and regeneration of the skin. Cerabellina and Eucerit had a lipid effect. The plant dyes and color pigments served to tint the skin. The bentonite particles had a peeling effect. The fragrances lastingly covered the typical smell of smokers and the urea kept the skin moist for longer.

Example 6

The preparation of a protective product for the nursing staff, which comes into contact with chemotherapeutic agents.

The cleansing / protective paste served to protect the skin from chemicals such as chemotherapeutic agents to absorb them so that they could not penetrate the skin barrier.

• - 6 Gewichtsteile von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 50 Gewichtsteile von Bienenwachspartikeln (D) einer mittleren Teilchengröße d₅₀ von 200 µm,
• - 2 Gewichtsteile nanokristalliner Cellulose (CNC) (C) einer mittleren Teilchengröße d₅₀ von 650 ± 100 nm,
• - 1 Gewichtsteil molekulardisperser Wolframatophosphorsäure-Hydrat {H₃[P(W₃O₁₀)₄]0· xH₂O, CAS-Nr. 1343-93-7 (D),
• - 0,5 Gewichtsteile Dikaliumhydrogenphosphat als Puffer (D) und
• - 0,05 Gewichtsteile Simethicone® E900 Schauminhibitor (D)

in 40,45 Gewichtsteilen Wasser (E) unter sterilen Bedingungen und Durchperlen von Kohlendioxid dispergierte. Die resultierende pastöse Salbe wurde unter leichtem Rühren und Unterdruck entgast und in sterile Spender abgefüllt.It was prepared a pasty ointment as a protective film by

• 6 parts by weight of particles (A) of pyrogenic carbon of an average particle size d ₅₀ of 650 ± 50 nm,
• 50 parts by weight of beeswax particles (D) having an average particle size d ₅₀ of 200 μm,
• 2 parts by weight of nanocrystalline cellulose (CNC) (C) having an average particle size d ₅₀ of 650 ± 100 nm,
• 1 part by weight of molecularly dispersed tungstophosphoric acid hydrate {H ₃ [P (W ₃ O ₁₀ ) ₄ ] 0 .xH ₂ O, CAS no. 1343-93-7 (D),
• - 0.5 parts by weight of dipotassium hydrogen phosphate as buffer (D) and
• - 0.05 parts by weight of Simethicone® E900 foam inhibitor (D)

in 40.45 parts by weight of water (E) under sterile conditions and bubbled with carbon dioxide. The resulting pasty ointment was degassed with gentle stirring and reduced pressure and filled into sterile dispensers.

In cancer patients who had to undergo chemotherapy as described in Example 1, very strong drugs were absorbed into the body. Some of these drugs and their metabolites were excreted. This happened, among other things, via the skin. This meant that the environment of the cancer patients and especially the nursing staff were damaged in contact. Before and / or during the therapeutic intervention and during the care of the patients, the hands of the nursing staff were treated with the ointment. The ointment forms a protective film that absorbs drugs and metabolites. After the care and / or interruption of the care she was washed off. It turned out that the skin of the nursing staff had not been irritated or damaged and that no more drugs and metabolites could be detected on the skin.

Example 7

Provision and topical application of an ointment in the treatment of Calcinosis Cutis.

Calcinosis cutis refers to deposits within the skin consisting of calcium phosphate with the formation of calcium salt crystals. The resulting swelling may be associated with local inflammation, pain and / or plaque breakthroughs. As a treatment, the plaques are surgically removed.

• - 6 Gewichtsteilen von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 50 Gewichtsteilen von Bienenwachspartikeln (D) einer mittleren Teilchengröße d₅₀ von 200 µm,
• - 2 Gewichtsteilen nanokristalliner Cellulose (CNC) (C) einer mittleren Teilchengröße d₅₀ von 650 ± 100 nm,
• - 1 Gewichtsteil molekulardisperser Wolframatophosphorsäure-Hydrat {H₃[P(W₃O₁₀)₄]0· xH₂O, CAS-Nr. 1343-93-7 (D),
• - 0,5 Gewichtsteilen Dikaliumhydrogenphosphat als Puffer (D),
• - 0,05 Gewichtsteilen Simethicone® E900 Schauminhibitor (D),
• - 10 Gewichtsteilen Hexahydroxycyclohexanhexaphosphorsäureestersalz-Nanopartikel (E) (Natriumsalz der Phytinsäure) einer mittleren Teilchengröße von 650 ± 150 nm und
• - 1 Gewichtsteil Polyethylenglykol (PEG) zur Öffnung der Hautporen

in 40,0 Gewichtsteilen Wasser (E) unter sterilen Bedingungen und Durchperlen von Kohlendioxid dispergierte. Die resultierende pastöse Salbe wurde unter leichtem Rühren und Unterdruck entgast und in sterile Spender abgefüllt.To prevent inflammation and against further deposits was an ointment

• 6 parts by weight of particles (A) of pyrogenic carbon of a mean particle size d ₅₀ of 650 ± 50 nm,
• 50 parts by weight of beeswax particles (D) having an average particle size d ₅₀ of 200 μm,
• 2 parts by weight of nanocrystalline cellulose (CNC) (C) having an average particle size d ₅₀ of 650 ± 100 nm,
• 1 part by weight of molecularly dispersed tungstophosphoric acid hydrate {H ₃ [P (W ₃ O ₁₀ ) ₄ ] 0 .xH ₂ O, CAS no. 1343-93-7 (D),
• 0.5 part by weight of dipotassium hydrogen phosphate as buffer (D),
• - 0.05 part by weight of Simethicone® E900 foam inhibitor (D),
• Hexahydroxycyclohexanhexaphosphorsäureestersalz nanoparticles (E) (sodium salt of phytic acid) of an average particle size of 650 ± 150 nm and
• - 1 part by weight of polyethylene glycol (PEG) to open the skin pores

in 40.0 parts by weight of water (E) under sterile conditions and bubbled with carbon dioxide. The resulting pasty ointment was degassed with gentle stirring and reduced pressure and filled into sterile dispensers.

The ointment was applied to patients with calcinosis cutis on and around affected areas and effectively prevented inflammation and other deposits in the skin.

Example 8

The preparation and use of a lotion for the care of the scalp and hair roots

• - 4 Gewichtsteilen von Partikeln (A) aus pyrogenem Kohlenstoff einer mittleren Teilchengröße d₅₀ von 650 ± 50 nm,
• - 10 Gewichtsteilen von Cerabellina (B) einer mittleren Teilchengröße d₅₀ von 200 µm,
• - 1 Gewichtsteil nanokristalliner Cellulose (CNC) (C) einer mittleren Teilchengröße d₅₀ von 650 ± 100 nm,
• - 15 Gewichtsteilen Ethanol (E),
• - 5 Gewichtsteilen Panethol,
• - 0,5 Gewichtsteile Cinnamomum Zeylanicum Leaf Oil,
• - 0,1 Gewichtsteile Polyethylenglykol (PEG) und
• - 100 Gewichtsteilen Wasser

unter sterilen Bedingungen hergestellt und in Flaschen abgefüllt. Zur Anwendung wurde die Lotion in die behaarte Kopfhaut einmassiert und 15 Minuten lang einwirken gelassen. Danach wurde die Lotion mit lauwarmem Wasser abgespült. Die Behandlung wurde während einer Woche einmal täglich wiederholt. Dadurch wurde die Behaarung sichtbar dichter, weil auch kleinere Härchen durch den Reinigungseffekt wieder stärker wuchsen und noch funktionsfähige Haarwuchsfollikel wieder zum Haarwachstum angeregt wurden.To care for the scalp and hair roots, an aqueous lotion was made

• 4 parts by weight of particles (A) of pyrogenic carbon of an average particle size d ₅₀ of 650 ± 50 nm,
• 10 parts by weight of Cerabellina (B) having an average particle size d ₅₀ of 200 μm,
• 1 part by weight of nanocrystalline cellulose (CNC) (C) having an average particle size d ₅₀ of 650 ± 100 nm,
• 15 parts by weight of ethanol (E),
• - 5 parts by weight of Panethol,
• 0.5 part by weight of Cinnamomum Zeylanicum Leaf Oil,
• - 0.1 parts by weight of polyethylene glycol (PEG) and
• - 100 parts by weight of water

prepared under sterile conditions and bottled. For application, the lotion was massaged into the hairy scalp and allowed to act for 15 minutes. Thereafter, the lotion was rinsed with lukewarm water. The treatment was repeated once a day for one week. As a result, the hair became visibly denser, because even smaller hairs grew stronger again by the cleaning effect and still functional hair follicles were stimulated to hair growth again.

QUOTES INCLUDE IN THE DESCRIPTION

This list of the documents listed by the applicant has been generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.

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Claims (17)

Topical preparations containing (A) at least one type of carbon particles having an average particle size d ₅₀ = 650 ± 200 nm. Topical preparations after Claim 1 , characterized in that the average particle size d ₅₀ of (A) is 650 ± 200 nm. Topical preparations after Claim 1 or 2 characterized in that said at least one type of carbon particle (A) is selected from the group consisting of particles of biochar, pyrogenic carbon, biochar, charcoal, sifting residue of charcoal, lumber ashes, activated charcoal, coal, animal charcoal, animal carcass, pyrogenic carbon of different pyrolysis degree, functionalized coals, pretreated coals, washed coals, extracted coals, coke, natural coke, and incompletely outgassed coke. Topical preparations according to one of Claims 1 to 3 , characterized in that the topical preparations, the carbon particles (A), based on the respective total amount of a topical preparations, in an amount of 0.01 wt .-% to 10 wt .-%. Topical preparations according to one of Claims 1 to 5 , characterized in that it additionally (B) particles of an average particle size d ₅₀ of 10 nm to <1000 .mu.m, containing at least one type and / or consisting of at least one type of nanocrystalline and / or microcrystalline natural waxes and / or semisynthetic waxes the basis of natural waxes and / or biodegradable microplastics. Topical preparations after Claim 5 , characterized in that the particles (B) of natural and semisynthetic waxes using the gas antisolvent recrystallization (GAS) method, the PCA (Precipitation with a Compressed Fluid Antisolvent) method, the PGSS method (Particles from Gas Saturated Solutions) or the RESS process (Rapid Expansion of Supercritical Solutions) can be produced. Topical preparations according to one of Claims 1 to 6 characterized in that they additionally contain (C) particles of average particle size d ₅₀ from 10 nm to <1000 nm, containing at least one type and / or consisting of at least one type of nanocrystalline, nanofibrillar, microcrystalline and / or microfibrillar polysaccharides. Topical preparations after Claim 7 characterized in that the particles (C) are selected from the group consisting of cellulose nanofibers (CNF), microfibrillar celluloses (MFC), microcrystalline celluloses (MCC), nanofibrillar polysaccharides (NFP), nanocrystalline celluloses (CNC) and bacterial nanocelluloses (BNC) , Paper pulp waste from paper making and fibers, as well as particles from waste textiles, are selected. Topical preparations after Claim 7 or 8th , characterized in that the particles (C) have an average particle size d ₅₀ = 650 ± 200 nm. Topical preparations according to one of Claims 1 to 9 Characterized in that it additionally comprises (D) at least one polyoxometalate from the group consisting of unmodified sauerstoffersetzten, functionalized coated, grafted, aggregated, agglomerated, and supported Polyoxometallatmolekülen a largest molecular diameter ≤2 nm and Polyoxometallatnanopartikeln and Polyoxometallatmikropartikeln a mean particle size d ₅₀ from 1 nm to <1000 microns. Topical preparations according to one of Claims 1 to 10 characterized by further comprising (E) at least one ingredient selected from the group consisting of water, phyllosilicates, ground clays, bolus americus clays, healing earth, nutshells, willow bark, lapacho cuttings, siliceous earth, pumice stone, geopolymer, amber, Gemstones, trace elements and neutral inorganic salts, beta-glucans, glutathione, albumin, xylan, phytates, complexing agents, antioxidants, Radical scavengers, menthol, caffeine, teein, papain, esculin hemihydrate, carotenoids, lecithins, absc acid, cyanidin, guanidine, urea, thiourea, fillers, solvents, humectants, solubilizers, nonionic wetting agents, buffers, thickeners, binders, wraps, disintegrants, disintegrants, lubricants , Lubricants, mold release agents, flow control agents, antioxidants, preservatives, sweeteners, flavoring agents, absorption accelerators, alkalizing agents, acidulants, neutralizing agents, foam inhibitors and defoamers, dyes, color pigments, oxidizing agents, reducing agents, stabilizers, propellants, opacifiers, pearlescers, denaturants, plasticizers, minerals, Vitamins, micelles, superabsorbents, moisturisers, oils, fragrances, flavors, perfumes, moisturizers, moisturizers, active ingredients for the skin care, deodorizing agents, film formers, gelling agents, tannins, tanning agents, tannin extracts, bittering agents, plant extracts, honeys, colostrum, cytostatics, antibodies, immunoglobulins, essential and non-essential amino acids and fats, hyaluronic acid, aloe vera gel, liposomes, alkylene glycols, polyalkylene ether glycols, proteins , Peptides, carbohydrates, lipids, nucleic acids, nucleic acid fragments, antiviral compounds, antiinflammatory compounds, antibiotics, cell differentiation reagents, analgesics, anesthetics, anesthetics, contrast agents, enzymes, cytokines, antihistamines, immunomodulators, hemostatic agents, hormones, angiogenic and antiangiogenic agents, neurotransmitters, therapeutic Oligonucleotides, viral particles, growth factors, retinoids, cell adhesion factors, extracellular matrix glycoproteins, osteogenic factors, antibodies, antigens, steroids, analgesics, potassium sulfate, Royal jelly, propolis, encapsulated perfumes, nutrients, hexahydroxycyclohexane-hexaphosphate ester salt nanoparticles, and surfactants. Topical preparations according to one of Claims 1 to 11 characterized in that they are used as powders, solids, granules gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, and coatings on and / or components of toilet utensils, textile fabrics, face masks, envelopes, sanitary napkins, Tampons, gauze, patches, medical devices and release materials are present. Topical preparations according to one of Claims 1 to 12 , characterized in that its pH is between 3 and 7. Process for the preparation of topical preparations according to one of Claims 1 to 13 characterized in that (I) at least one type of particles (A) with at least one type of particles (B) and / or at least one type of particles (C) are mixed together and the resulting mixture homogenized and (II) the resulting homogenized mixture (AB), (AC) or (ABC) to powders, solids, granules, gels, creams, ointment lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, suppositories or foams and / or processed and / or / or applied in textile fabrics, face masks, gauze, envelopes, bandages, tampons, plasters, medical devices and / or release materials. Method according to Claim 14 , characterized in that (i) at least one type of particles (A) having at least one type of particles (B) and / or at least one type of particles (C) and / or at least one polyoxometalate (D) and / or at least an ingredient (E) and the resulting mixture (ABC), (ABD), (ABE), (ACD), (ACE), (ADE), (ABCD), (ABCE) or (ABCDE) homogenized. Use of the topical preparations according to one of the Claims 1 to 13 and according to the method according to Claim 14 or 15 prepared topical preparations as cosmetics, care products and products for saunas and steam baths and for the care of skin, in particular overlaps on the chest, abdomen and groin, mucous membranes, eyes, ears, mouth, lips, fingernails, toenails, cornea, warts and scars, at Excretions of noxa, drugs, toxins, medicines, acids, bases and odorants through the skin, in case of lesions, itching, intertrigo, burning, infections, in cancer therapy, chemotherapy, chondrocalcinosis, skin diseases such as: psoriasis, eczema, acne, eczema, atrophic Eczema, warts, rosacea, herpes, shingles, measles, mumps, rubella, chickenpox, hand-foot-and-mouth disease, hand and foot syndrome and redness, for preventative protection, to aid in the healing of existing infections, wounds or burns , in the decorative cosmetics, in the cosmetic facial care, in the hair care and in the personal care of humans and animals. Medical and decorative cosmetics, care products, products for saunas and steam baths, powders, solids, gels, creams, ointments, lotions, drops, sprays, metered aerosols, gargles, lozenges, enemas, enemas, suppositories, foams and toilet utensils, textile fabrics, face masks, envelopes , Bandages, tampons, gauze, plasters, medical devices and release materials, characterized in that it comprises at least one topical preparation according to one of the Claims 1 to 13 and / or at least one according to the method according to Claim 14 or 15 prepared, contains or consists of topical preparation.