DE102006016692B4 - Balance for weighing pharmaceutical or chemical products and use of a device with such a balance - Google Patents

Abstract

Balance for weighing pharmaceutical or chemical products, with
A test space (86) bounded downwardly by a test chamber floor (50),
- A force measuring device, which is arranged below the test space (86) in a receiving space (85), and
- A arranged above the force measuring device stamping punch (30), which consists of at least one weighing plate (10) and a punch (20), wherein
- The weighing plate (10) in the test chamber (86) is arranged and on the top of the weighing plate (10) the products to be weighed are placed,
- And the punch (20) through a test chamber in the floor (50) arranged Prüfraumöffnung (40) down from the test room (86) into the receiving space (85) protrudes and the weight of the weigh plate (10) launched products to be weighed in initiates the force measuring device,
characterized in that
in the test chamber (86) on or above the test chamber floor (50) an open-top, annular basin (1) is arranged with an outer edge ...

Description

The The invention relates to a balance for weighing pharmaceutical or chemical products, with a test room, a force measuring device, which below the test room is arranged in a receiving space, and with a above the force measuring device arranged weighing stamp. The invention further relates to the use a device with such a balance for quality control pharmaceutical products.

at the quality control from mass produced solid pharmaceutical, chemical or other technical products, such as, for example, tablets, Pills, oblongs, pellets, electronic components, screws or the same is it usual to take samples from the current production and these, for example according to dimensions, weight, strength, composition and the like to investigate.

From the WO 2004/071659 A1 For example, a device for quality control of solid pharmaceutical products is known, which has one or more testing devices for testing one or more of the above-mentioned properties. The testing of the products by means of the test devices takes place in this known device in a closed and compared to the environment subjected to a negative pressure chamber to prevent leakage of abrasion of the examined pharmaceutical products containing dust into the environment. This is particularly important for the protection of operating personnel, as pharmaceutical products contain active ingredients which, when administered in small doses, have a medicinal, health-promoting effect, but have harmful effects when administered in large quantities or when permanently exposed to the human body. Similar problems are also known from the handling of chemical products and electronic components.

Especially important in such quality control devices is therefore also that they are easy and thorough to clean, for example, to accumulate large quantities To effectively prevent abrasion-containing dust, and to be distorted by a change of the products to be examined by dust from previously examined products containing dust to avoid.

Around Such devices for quality control pharmaceutical Easy to clean products, are largely all components of the test equipment, which are not immediate at the place of the test taking place must be arranged in a receiving space separated by an intermediate floor from the test room arranged. Only the absolutely necessary encoders and sensors extend through, for example, by means of sleeves, protective lenses and the like sealed openings through into the test room.

at one executed as a scale test equipment occurs the problem that a free mechanical connection between force measuring device, and weighing plate is required. These Connection is carried out for example by means of a stamp, wherein the term stamp all conceivable mechanical connections between the Force measuring device and the weighing plate comprises. To a weight measurement to enable The stamp must be free to move and may be due to the very low measured weights and the high clock rate of each other following measurements are not caused by friction, for example by a sliding bearing of the punch, a stamp enclosing and the test room opposite the Receiving space sealing cuff or the like, on his Movement be inhibited.

In order not to interfere with the weighing by friction it is therefore like in 6 shown usual, one from weighing plate 100 and stamp 200 existing weighing punch 300 free through a connection opening 400 in the lower intermediate floor 500 from the top 600 and lower 500 Intermediate floor existing floor 700 to pass, with the upper shelf 600 a weighing opening 800 in which the weighing dish 100 is arranged freely movable, and the weighing plate 100 flush with the surface of the upper, usually removable false floor 600 concludes. To prevent penetration of detergent in the under the lower shelf 500 In addition, to make it difficult to locate the receiving space when cleaning the device is known, one around the connection opening 400 circumferential Süllrand 900 provided.

adversely At this state of the art is that a dustproof seal between the test room and recording room not possible is. Dust from the test room can through the weighing opening between weighing dish and upper shelf on the lower shelf fall and from there through the connection opening in the receiving space get there in big ones Accumulate quantities and open them the receiving space, for example when carrying out maintenance work, escape. This creates for the operator the health risks described above.

• A1 Die Aufgabe wird gelöst durch eine Waage zur Wägung pharmazeutischer oder chemischer Erzeugnisse, mit einem Prüfraum, welcher nach unten durch einen Prüfraumboden begrenzt ist, einer Kraftmesseinrichtung, welche unterhalb des Prüfraums in einem Aufnahmeraum angeordnet ist, sowie einem oberhalb der Kraftmesseinrichtung angeordneten Wiegestempel, welcher wenigstens aus einem Wiegeteller und einen Stempel besteht, wobei der Wiegeteller im Prüfraum angeordnet ist und auf die Oberseite des Wiegetellers die zu wägenden Erzeugnisse auflegbar sind, und der Stempel durch eine im Prüfraumboden angeordnete Prüfraumöffnung hindurch nach unten aus dem Prüfraum in den Aufnahmeraum ragt und die Gewichtskraft der auf den Wiegeteller aufgelegten zu wägenden Erzeugnisse in die Kraftmesseinrichtung einleitet. Im Prüfraum ist auf oder über dem Prüfraumboden ein oben offenes, ringförmiges Becken angeordnet mit einem äußeren Rand und einem inneren Rand, welcher einen oben und unten offenen, über der Prüfraumöffnung angeordneten Innenraum peripher umgibt, wobei das Becken bis zu einem vorgegebenen Niveau mit einer Flüssigkeit gefüllt ist, der Stempel den Innenraum von oben nach unten durchragt, und an dem Wiegestempel ein Eintauchkörper angeordnet ist, welcher von oben her in das Becken und die Flüssigkeit eintaucht und so geformt ist, dass der in die Flüssigkeit eintauchende Teil des Eintauchkörpers den Innenraum ringsum peripher umgibt und der Innenraum und damit auch der Aufnahmeraum durch den Eintauchkörper, den Wiegestempel und die Flüssigkeit staubdicht gegen den Prüfraum abgedichtet sind. Mit einem ringförmigen Becken ist hier ein solches von beliebiger Form gemeint, welches einen nicht zu dem Becken gehörenden, sondern durch den inneren Rand davon abgegrenzten Innenraum rundum peripher umlaufend umgibt. Der äußere Rand kann insbesondere z. B. eine in Draufsicht von oben runde oder eine quadratische Form besitzen; aber auch andere Formen sind im Rahmen der Erfindung möglich. Dasselbe gilt für den inneren Rand. Die horizontale Querschnittsfläche des Beckens braucht nicht notwendigerweise in jeder Höhe gleich groß oder von gleicher Form zu sein. Das Flüssigkeitsniveau ist bevorzugt so gewählt, dass in jedem Belastungszustand der Waage, insbesondere auch bei unbelasteter Waage, der in die Flüssigkeit eintauchende Teil des Eintauchkörpers den Innenraum ringsum peripher umgibt und somit die staubdichte Abdichtung des Prüfraums gegen den Aufnahmeraum gewahrt bleibt.
• A2 Der Eintauchkörper kann insbesondere als Zylindermantel ausgebildet sein, welcher von dem Wiegeteller nach unten absteht.
• A3 Der Eintauchkörper ist bevorzugt von dem inneren Rand durch einen Spalt beabstandet, welcher ausreichend schmal ist, um bei einem Spülen des Beckens oder bei einer Erschütterung desselben ein Aufsteigen der Flüssigkeit in dem Spalt über den inneren Rand hinweg zu verhindern.
• A4 Bevorzugt ist der Eintauchkörper von dem inneren Rand durch einen Spalt beabstandet, welcher ausreichend breit ist, ein durch Kapillarkräfte bedingtes Aufsteigen der Flüssigkeit in dem Spalt über den inneren Rand hinweg zu verhindern.
• A5 Bevorzugt ist der äußere Rand niedriger als der innere Rand ausgeführt, so dass die maximale Höhe des Flüssigkeitsniveaus durch die Höhe des äußeren Randes vorgegeben und ein Überlaufen des Beckens nach innen über den inneren Rand hinweg ausgeschlossen ist.
• A6 In dem äußeren Rand kann sich eine Überlauföffnung befinden, durch welche die maximale Höhe des Flüssigkeitsniveaus vorgegeben und ein Überlaufen des Beckens nach innen über den inneren Rand hinweg ausgeschlossen ist.
• A7 Die Flüssigkeitsoberfläche des Beckens ist bevorzugt so groß, dass durch ein Vergrößern der Eintauchtiefe des Eintauchköpers um einen Millimeter ein Anstieg des Flüssigkeitsniveaus von weniger als 0,1 mm, bevorzugt von weniger als 0,01 mm hervorgerufen wird.
• A8 Der Messfehler der Wägung, welcher durch die veränderliche Eintauchtiefe des Eintauchkörpers und die damit verbundene veränderliche auf diesen wirkende Auftriebskraft hervorgerufenen wird, ist gemäß einer vorteilhaften Variante der Erfindung mittels einer Kompensationseinrichtung mechanisch oder rechnerisch kompensierbar.
• A9 Die Kompensationseinrichtung kann insbesondere eine EDV-Einrichtung umfassen und imstande sein, die vertikale Auslenkung des Eintauchkörpers aus einer Grundstellung zu ermitteln, anhand der Höhe des Flüssigkeitsniveaus, der Dichte der Flüssigkeit und der Form des Eintauchkörpers dessen Auftriebskraft in der Flüssigkeit in Abhängigkeit von seiner vertikalen Auslenkung zu bestimmen und die so ermittelte Auftriebskraft zur rechnerischen Kompensation des Messfehlers heranzuziehen.
• A10 Bevorzugt ist das Becken von dem Prüfraumboden abnehmbar, beispielsweise zu Reinigungszwecken.
• A11 Auf dem Prüfraumboden ist bevorzugt ein um die Prüfraumsöffnung umlaufender Süllrand in Form eines in den Innenraum des Beckens eingreifenden hohlzylinderförmigen Zapfens angeordnet, welcher das Becken auf dem Prüfraumboden positioniert.
• A12 Bevorzugt ist der Süllrand höher als der innere Rand des Beckens.
• A13 Gemäß einer Variante sind das Becken und der Prüfraumboden fest miteinander verbunden.
• A14 Über dem Becken kann vorteilhaft ein in vertikaler Richtung im Wesentlichen bündig mit dem unbelasteten Wiegeteller abschließender, abnehmbarer Zwischenboden angeordnet sein, welcher eine Wiegeöffnung aufweist, in welcher der Wiegeteller in vertikaler Richtung frei beweglich angeordnet ist.
• A15 Die Oberseite des Zwischenbodens schließt bevorzugt bündig mit der Oberseite des unbelasteten Wiegetellers ab.
• A16 Der Wiegeteller oder der Wiegestempel kann abnehmbar sein, was z. B. zu Reinigungszwecken vorteilhaft ist.
• A17 Bevorzugt ist der Wiegestempel einstückig ausgebildet und somit der Wiegeteller nicht von dem Stempel abnehmbar.
• A18 Bevorzugt besitzt der Wiegestempel eine Masse von 120 bis 130 g, vorzugsweise 125 g.
• A19 Der Prüfraum ist gemäß einer bevorzugten Ausführungsform der Erfindung nicht nur gegen den Aufnahmeraum, sondern auch gegen seine gesamte übrige Umgebung staubdicht ausgeführt. Zu diesem Zweck kann z. B. auf den Prüfraumboden ein unten offenes halbschalenartiges Gehäuse aufgesetzt sein, dessen Innenraum den Prüfraum bildet. Auf diese Weise ist mit hoher Sicherheit gewährleistet, dass kein Bruchstück, Abrieb oder Staub des pharmazeutischen oder chemischen Erzeugnisses aus dem Prüfraum austreten und die Umgebung kontaminieren kann.
• A20 Bevorzugt weist eine erfindungsgemäße Waage eine Einrichtung, welche insbesondere z. B. als Nachfülleinrichtung oder als ein Ausgleichsbehälter ausgebildet sein kann, auf, welche ein Absinken des Flüssigkeitsniveaus in dem Becken unter einen vorgegebenen Mindestpegel zu verhindern imstande ist. Auf diese Weise wird einem durch Verdunstung bedingten Absinken des Flüssigkeitsniveaus unter den Mindestpegel verhindert, so dass auf Dauer oder zumindest für längere Zeit ein Versagen der staubdichten Abdichtung des Aufnahmeraums gegen den Prüfraum auf Grund eines zu niedrigen Flüssigkeitsniveaus in dem Becken ausgeschlossen ist. Der Mindestpegel ist bevorzugt so gewählt, dass dann, wenn das Flüssigkeitsniveau auf Höhe des Mindestpegels steht, in jedem Belastungszustand der Waage, insbesondere auch bei unbelasteter Waage, der in die Flüssigkeit eintauchende Teil des Eintauchkörpers den Innenraum ringsum peripher umgibt und somit die staubdichte Abdichtung des Prüfraums gegen den Aufnahmeraum gewahrt bleibt.
• A21 Gemäß einer Variante weist die Waage einen Pegelsensor auf, welcher bei Absinken des Flüssigkeitsniveaus in dem Becken unter einen vorgegebenen Minimalpegel oder unter den Mindestpegel ein Schaltsignal oder ein Alarmsignal auszugeben imstande ist.
• A22 Die Aufgabe wird ferner gelöst durch eine Verwendung einer Vorrichtung zur Qualitätskontrolle pharmazeutischer Erzeugnisse, welche Vorrichtung mindestens eine Prüfeinrichtung mit einererfindungsgemäßen Waage der oben beschriebenen Art umfasst.

The invention is therefore the task ground to develop a balance, which allows a dust-tight seal between a first space in which the force measuring device is arranged, and a second space in which the weighing pan is arranged.

• A1 The object is achieved by a balance for weighing pharmaceutical or chemical products, with a test space, which is bounded below by a test room floor, a force measuring device, which is arranged below the test room in a receiving space, and a above the force measuring device arranged weighing punch, which consists of at least one weighing plate and a stamp, wherein the weighing plate is arranged in the test room and on the top of the weighing plate the products to be weighed can be placed, and the punch protrudes through a test chamber arranged in the test chamber opening down from the test room into the receiving space and the Weight of the launched on the weighing plate to be weighed products in the force measuring device initiates. In the test room is on or above the Prüfraumboden an open-top, annular basin arranged with an outer edge and an inner edge, which surrounds a top and bottom open, arranged above the Prüfraumöffnung interior peripherally, the basin up to a predetermined level with a liquid is filled, the punch penetrates the interior from top to bottom, and on the rocker an immersion body is arranged, which dips from above into the tank and the liquid and is shaped so that the immersed in the liquid part of the immersion body, the interior space around surrounds peripherally and the interior and thus the receiving space are sealed by the immersion body, the stamping die and the liquid dustproof against the test room. With an annular basin here is meant such of any shape, which surrounding a not belonging to the pelvis, but by the inner edge thereof delimited interior circumferentially peripherally circumferentially. The outer edge can in particular z. B. have a top view in plan from above or a square shape; but other forms are possible within the scope of the invention. The same goes for the inner edge. The horizontal cross-sectional area of the basin does not necessarily have to be the same size or the same shape at any height. The liquid level is preferably chosen so that in each load state of the balance, especially in unloaded balance, the immersed in the liquid part of the immersion surrounds the interior peripherally peripherally and thus the dust-tight seal of the test chamber is maintained against the receiving space.
• A2 The immersion body may be formed in particular as a cylinder jacket, which protrudes from the weighing plate down.
• A3 The dip body is preferably spaced from the inner edge by a gap which is sufficiently narrow to prevent the liquid in the gap from rising above the inner edge upon purging or vibration of the pelvis.
• A4 Preferably, the dip body is spaced from the inner edge by a gap which is sufficiently wide to prevent capillary forces caused liquid to rise in the gap across the inner edge.
• A5 Preferably, the outer edge is made lower than the inner edge, so that the maximum height of the liquid level is dictated by the height of the outer edge and the overflow of the pelvis inwardly beyond the inner edge is eliminated.
• A6 There may be an overflow opening in the outer edge, which defines the maximum height of the liquid level and prevents overflow of the basin inwardly beyond the inner edge.
• A7 The liquid surface of the basin is preferably so large that increasing the immersion depth of the immersion body by one millimeter causes an increase in the liquid level of less than 0.1 mm, preferably less than 0.01 mm.
• A8 The measurement error of the weighing, which is caused by the variable depth of immersion of the immersion body and the associated variable acting on this buoyancy force, according to an advantageous variant of the invention by means of a compensation device mechanically or mathematically compensated.
• A9 The compensation device may in particular comprise an EDP device and be able to determine the vertical deflection of the immersion body from a home position, based on the height of the liquid level, the density of the liquid and the shape of the immersion body whose buoyancy force in the liquid as a function of its vertical Determine deflection and use the thus determined buoyancy force for computational compensation of the measurement error.
• A10 Preferably, the basin is removable from the test chamber floor, for example for cleaning purposes.
• A11 On the test chamber floor, a coaming edge circulating around the test chamber opening is preferably arranged in the form of a hollow-cylindrical pin engaging in the interior of the basin, which position the basin on the test chamber floor.
• A12 Preferably, the Süllrand is higher than the inner edge of the basin.
• A13 According to one variant, the pelvis and the test chamber floor are firmly connected to each other.
• A14 Over the basin may advantageously be arranged in the vertical direction substantially flush with the unloaded weighing plate final, removable intermediate bottom, which has a weighing opening in which the weighing plate is arranged to move freely in the vertical direction.
• A15 The top of the false bottom is preferably flush with the top of the unloaded weighing pan.
• A16 The weighing plate or the weighing punch may be removable, which may be for B. is advantageous for cleaning purposes.
• A17 Preferably, the weighing punch is integrally formed and thus the weighing plate can not be removed from the punch.
• A18 Preferably, the weighing punch has a mass of 120 to 130 g, preferably 125 g.
• A19 The test room is executed according to a preferred embodiment of the invention not only against the receiving space, but also dust-tight against its entire rest environment. For this purpose, z. B. be placed on the test room floor a bottom open shell-like housing whose interior forms the test room. In this way it is ensured with great certainty that no fragment, abrasion or dust of the pharmaceutical or chemical product can escape from the test chamber and contaminate the environment.
• A20 Preferably, a balance according to the invention comprises a device which in particular z. B. may be formed as a refill or as a surge tank, which is to prevent a decrease in the liquid level in the tank below a predetermined minimum level is capable. In this way, a decrease in the liquid level below the minimum level caused by evaporation is prevented, so that a failure of the dust-tight seal of the receiving space against the test chamber due to a too low liquid level in the basin is excluded permanently or at least for a long time. The minimum level is preferably chosen so that, when the liquid level is at the minimum level, in each load state of the balance, especially in unloaded balance, immersed in the liquid part of the immersion surrounds the interior circumference peripherally and thus the dust-tight seal of the Test room against the recording room is maintained.
• A21 According to a variant, the balance has a level sensor which is capable of outputting below a predetermined minimum level when the level of liquid in the basin falls or below the minimum level, or an alarm signal is output below the minimum level.
• A22 The object is further achieved by a use of a device for quality control of pharmaceutical products, which device comprises at least one testing device with a scale according to the invention of the type described above.

In Modification of the design of the scale according to claim 1 can the the weighing stamp arranged and from above into the basin and the liquid immersing immersion body be shaped so that the immersed in the liquid part of the Submersible body surrounding at least an upper part of the inner space peripherally peripherally and the interior and thus the receiving space by the immersion body, the Weighing stamp and the liquid dustproof against the test room are sealed.

The Libra preferably comprises one arranged in a first space Force measuring device and a arranged to be movable in the vertical direction Weighing plate and a weighing plate with the force measuring device connecting stamp comprehensive stamping punch, wherein the weighing plate in a second space separated from the first space in vertical Direction is movably arranged and the stamp by an in an intermediate floor separating the first room from the second room arranged connection opening shall pass through. Preferred is on the false floor in the second room in the area the connection opening Cymbal can be arranged, which has an outer edge, as well a circumferential around a arranged in the bottom of the basin central opening, inner edge, wherein the punch through the central opening of the Passing through the pelvis into the second room and the one with the stamp Connected weighing plate is designed so that it over the inner edge of the basin and extends along a closed, around the inner edge encircling circumferential line in one in the basin filled liquid dips, leaving a dust-tight seal between the top and the lower room takes place or arises.

Of the The weighing plate can be concentric with the stamp on its underside arranged, surrounding the central opening of the pelvis inner Border enclosing, down into the liquid contained in the basin, hollow cylindrical shell have, wherein in a horizontal cross section, the inner dimensions of the coat are bigger, as the outside dimensions of the Inner rim.

The gap existing between the jacket and the inner edge is preferably sufficiently small to to prevent the fluid from rising above the inner rim when flushing the pelvis.

Of the Gap between mantle and inner edge is preferably sized so large that the occurrence of capillary forces is prevented.

The filled in the basin Liquid takes prefers a certain, reproducible liquid level.

One certain, reproducible liquid level in the basin can z. B. can be achieved by the outer edge lower than the inner edge is executed. Furthermore, a specific, reproducible liquid level be reached in the basin by arranged in the outer edge of an overflow opening is.

Prefers the basin has a sufficiently large liquid surface, by a level change the fluid level in the basin through the inlet and Dipping the fluid reaching into the liquid Part of the weighing pan neglect too can.

Prefers owns the balance according to the invention Means for compensating the buoyancy of the liquid dipping part of the weighing pan.

The Means for compensating the buoyancy, in particular an evaluation device which determines the vertical displacement of the punch and the level of fluid, the density of the liquid and the geometry of the liquid dipping part of the weighing plate whose buoyancy force in the liquid determined and adds this force to the display of the force measuring device.

The Basin can be removable from the intermediate floor. On the shelf can one around the connection opening circumferential Süllrand in the form of one in the central opening arranged in the pelvis hollow cylindrical pin, which positions the pelvis on the intermediate floor. The Süllrand is preferably higher than the inner edge of the basin.

According to one Variant basin and the intermediate floor are firmly connected.

Above that Basin can be a second, in a vertical direction substantially flush with the unloaded weighing plate final, removable intermediate bottom be arranged, which has a cross-sectional shape of the weighing pan corresponding and in the cross-sectional dimensions slightly larger than the weighing dish executed cradle opening in which the weighing dish is free in the vertical direction is movably arranged. The weighing plate is preferably removable. The weighing plate comprising the weighing plate and the stamp can executed in one piece be. The weighing punch can be removable. The weighing punch weighs preferably 125 g.

A Device for quality control Pharmaceutical products preferably comprises one over the Environment enclosed test room, one at least partially arranged under the test room, and of this through a test room floor separated, opposite the test room and the environment enclosed recording room, as well as at least one test equipment, wherein at least one testing device includes such a balance.

Of the The ram preferably protrudes from the receiving space forming the first space by a in the intermediate floor forming Prüfraumboden arranged connection opening in the the second room testing room into it, being around the connection opening around on the inner edge of the pelvis projecting, a hollow cylindrical pin forming Süllrand is arranged, whose horizontal cross section interior dimensions that are larger, as the cross-sectional dimensions of the punch, and its outer dimensions approximately the internal dimensions of the horizontal cross section of the central opening of the basin correspond, so that the basin by means of the hollow cylindrical pin on the test room floor is positioned.

Of the test chamber may have a first, the connection opening and the first intermediate floor forming lower floor, as well as a second a weighing opening approximately corresponding in size to the weighing dish, comprising the second intermediate floor, removable upper floor, the upper floor being flush Completes with the weighing plate in the unloaded state and the Basin between the upper and the lower floor is arranged.

Of the For example, the first room may be a room in which the force measuring device and optionally required control and evaluation devices, Recording devices for data acquisition and the like arranged could be. The second space may be, for example, the environment, with at the balance according to the invention through the pelvis and along a closed perimeter immersed in the liquid contained in the basin weighing punch the recording room opposite the environment especially during the operation of the balance is sealed dust-tight.

It is also conceivable that the second room a test room, for example, from the WO 2004/071659 A1 known device for quality control of pharmaceutical products. Again, in the balance according to the invention by the basin and along the closed perimeter immersed in the basin filled liquid weighing plate a dust-tight seal in this case the test room reached by the receiving space, for example, the penetration of abrasion of the tested pharmaceutical products containing dust to prevent from the testing room into the receiving space. Occurring dust falls in the balance according to the invention in the preferably larger outer dimensions than the weighing dish having basin and is bound in the liquid contained in the basin.

Of the inner edge of the pelvis is preferably higher than the outer edge trained to overflow of the basin in the area of the central opening and thus in the area the connection opening to prevent. It is also conceivable, an overflow opening in the outer edge at a lower height than that Height of to arrange inner edge, creating a reproducible, uniform liquid level Ensuring the pool is easy in the pool by overflowing either over the lower outer edge away or through the overflow opening filled becomes.

The inventive balance points opposite The prior art has the advantage that a dust-tight seal between the first and the second room during operation of the balance is ensured.

A advantageous embodiment of the invention provides that the weighing plate arranged on its underside a concentric with the stamp, the around the central opening of the pelvis encircling inner edge, down into the in the liquid contained in the basin reaching, hollow cylindrical Sheath has, wherein in a horizontal cross section, the inner dimensions of the coat are bigger, as the outer dimensions of the inner margin, leaving a gap between the mantle and the inner Edge arises. The basin has larger dimensions in the horizontal direction on, as the weighing plate. The term concentric refers to it a symmetry to a common center. For example, any different geometric shapes then concentrically arranged if the individual forms all have the same center of gravity.

A advantageous embodiment of the invention provides that the between Cloak and inner edge existing gap is sufficiently small to with a rinse of the pelvis, for example by means of one from above into the pelvis directed liquid jet an increase of the liquid over the to prevent the inner edge. This will be one over the State of the art achieves considerably improved splash protection, there under the weighing plate splashing and in the gap between mantle and inner edge of oppressive water or detergent similar to that a labyrinth seal acting gap is slowed down.

A advantageous embodiment of the invention provides that the gap between coat and inner edge is so large that the appearance of capillary forces is prevented. By a too small trained gap, which the arising of capillary forces favor would, would create a very thin one liquid film between the opposite the inner edge of the basin movably arranged jacket which due to in the liquid film occurring relatively high boundary layer friction in particular fast consecutive measurements affect measurement accuracy would.

A advantageous embodiment of the invention provides that in the basin filled liquid in the basin a certain, reproducible liquid level occupies. The certain, reproducible level of liquid on the one hand sure that the weighing plate is along a closed perimeter in the filled into the basin liquid dips, and on the other hand, the influence of the buoyancy of in the liquid dipping part of the weighing pan determined as the buoyancy in the liquid dipping part of the weighing pan in unloaded condition always is equal to.

A Another advantageous embodiment of the invention provides that a certain, reproducible level of fluid in the pool is achieved by the outer edge lower than the inner edge is executed. This is to achieve the determined, reproducible liquid level as long as liquid filled in the basin, until the basin over overflows the outer edge.

A Another advantageous embodiment of the invention provides that a certain, reproducible level of fluid in the pool is achieved by the outer edge has an overflow opening. This is to achieve the specific, reproducible liquid level so long liquid filled in the basin, until the basin over the overflow opening overflows.

Another advantageous embodiment of the invention provides that the basin has a sufficiently large, limited by the outer edge and the inner edge liquid surface to a level change of the liquid level in to be able to neglect the basin by the entry and exit of the reaching into the liquid part of the weighing plate.

A additional advantageous embodiment of the invention is characterized by Means for compensating the buoyancy of the submerged in the liquid Part of the weighing plate.

A additional advantageous embodiment of the invention provides that the means include an evaluation device for compensating the buoyancy, which directly or starting from the display of the force measuring device determines the vertical displacement of the punch and based the known liquid level, the density of the liquid and the geometry of the liquid dipping part of the weighing plate whose buoyancy force in the liquid determined and adds this force to the display of the force measuring device. The term display encompasses any kind of output signal of the Force measuring device.

A advantageous embodiment of the invention provides that the pelvis Removable from the false floor and can be placed again and thus slightly outside of the scale range can be cleaned.

A Particularly advantageous embodiment of the invention provides that on the intermediate bottom a circulating around the connection opening Süllrand in Shape one in the central opening the basin is arranged in the hollow cylindrical pin, which positions the pelvis on the intermediate floor. The Süllrand fulfilled thereby a double task: on the one hand it positions the pelvis, for To others, it facilitates the cleaning of the balance by preventing the penetration of liquid in the first space through the connection opening, for example made difficult with removed pelvis. Basically, the pelvis is also conceivable independently from the Süllrand by means arranged on the intermediate bottom pin or the like to position.

A another, particularly advantageous embodiment of the invention sees before, that the Süllrand is higher, as the inner edge of the pelvis. This creates for an intermediate Cloak and inner edge ascending fluid column a sudden, discontinuous Cross-sectional expansion, thereby reducing the risk that between the shell of the weighing plate and the inner edge of the basin possibly ascending fluid through the connection opening penetrates into the receiving space.

A advantageous embodiment of the invention provides that the pelvis and the intermediate floor are firmly connected.

A additional Particularly advantageous embodiment of the invention provides that above the Basin a second, in the vertical direction substantially flush with the unloaded weighing plate final, removable intermediate floor arranged is, which corresponds to a cross-sectional shape of the weighing pan and in the cross-sectional dimensions has slightly larger than the weighing dish executed weighing opening, in which the weighing plate arranged freely movable in the vertical direction is. Occurring dust falls in the execution the balance according to the invention with a second, over arranged the basin and flush with through the unloaded weighing plate final intermediate floor the remaining gap of the weighing opening between weighing dish and second intermediate floor in the preferably larger outer dimensions than the weighing plate having pelvis. Especially when dealing with pharmaceutical Products which are administered in small quantities to humans harmless, but in big ones Amounts harmful Containing active ingredients, it is important to ensure that operators, that constantly with the pharmaceutical products, only a small one Exposure to the active ingredients is exposed. An additional one Advantage of the balance according to the invention is, therefore, that the dust occurring and falling through the weighing opening is bound in the liquid contained in the basin and thus can no longer be inhaled by the operator.

A advantageous embodiment of the invention provides that the weighing plate is removable, for example, to easily remove the basin for cleaning to be able to after first the weighing plate has been removed.

A Another advantageous embodiment of the invention provides that of the weighing plate and the punch comprehensive stamping punch in one piece accomplished is. If the weighing plate has a down-reaching coat, The one-piece stamping die also includes this coat.

A Design provides that the basin has a closable inlet and a lockable Expiration, over which rinsed the pelvis and can be cleaned with it.

A additional advantageous embodiment of the invention provides that the stamping punch is removable. Just like a two- or multi-piece weighing punch allows the removability of the one-piece executed stamping a simple Slimming the pelvis.

A particularly advantageous embodiment The invention provides that the weighing punch weighs 125 g.

A additional advantageous embodiment of the invention provides a device for quality control pharmaceutical products, which have a Environment enclosed test room, one at least partially arranged under the test room, and of this through a test room floor separated, opposite the test room and the environment enclosed recording room, as well as at least one Includes testing equipment, wherein at least one testing device a balance according to one of the claims 1 to 19.

A Particularly advantageous embodiment of the invention provides that the weighing punch from the receiving space forming the first space a in the intermediate floor forming Prüfraumboden arranged connection opening in the the second room testing room protrudes, wherein around the connection opening around a inner edge of the pelvis projecting, a hollow cylindrical pin forming Süllrand is arranged, whose horizontal cross section interior dimensions that are larger, as the cross-sectional dimensions of the punch, and its outer dimensions approximately the inner dimensions of the horizontal cross section of the central opening of the Correspond to the pelvis so that the pelvis by means of the hollow cylindrical pin on the test room floor is positioned. The test room is preferably opposite The environment subjected to a negative pressure to the leakage dust from the abrasion of pharmaceutical products the test room to prevent the environment. By using the balance according to the invention Is it possible, the test room across from the recording room completely seal dust-tight. About that In addition, the allowed along a closed perimeter in the Basin dipping weighing dishes the receiving room with another, preferably higher Pressure as the test room to act on.

A advantageous embodiment of the invention provides that the test chamber floor a first, the connection opening having and the first intermediate floor forming lower floor, and a second one in its dimensions about the weighing plate corresponding weighing opening comprising, the second intermediate bottom forming, removable upper Soil covers, with the top soil flush with the weighing dish in Completes unloaded state and the removable pelvis between the upper and the lower Floor is arranged.

Summary the drawing, in which show schematically:

1 a section through an intermediate floor with a arranged on the intermediate floor basin and a dipping into the basin weighing dish,

2 the cut AA 1 .

3 a perspective view of the basin of the balance according to the invention,

4 a top view of the basin 3 .

5 the same cut as 1 with upper intermediate floor arranged above the basin,

6 the state of the art in one 1 appropriate representation,

7 a weighing punch of a balance according to the invention, with an immersion body arranged thereon, which dips into a liquid in a basin and thereby seals a test area dust-tight against a receiving space, and

8th the basin and the test chamber floor of 7 and a downwardly open surge tank immersed in the basin, which prevents a lowering of the liquid level in the pool below a predetermined minimum level.

All figures except 6 relate to advantageous embodiments of the invention. The 1 and 5 - 8th are cross-sectional representations.

An in 1 illustrated weighing punch 30 includes a weighing plate 10 and a stamp 20 , The stamping punch 30 is part of a not shown, the stamping punch 30 and a force measuring device comprising scale, wherein the force measuring device in a first space 85 is arranged and the weighing plate 10 in one of the first room 85 separate second room 86 is arranged. The stamping punch 30 is freely movable in the vertical direction. The one by one in the first room 85 from the second room 86 separating test room floor 50 arranged test room opening 40 passing stamp 20 connects the force measuring device, such as a load cell, with the weighing plate 10 , On the test room floor 50 is one around the inspection room opening 40 circumferential Süllrand 90 arranged. The Süllrand 90 has the shape of a hollow cylindrical pin. On the test room floor 50 is in the second room 86 in the area of the test chamber opening 40 a basin 1 arranged, which has an outer edge 2 , as well as one in the bottom of the basin 1 arranged, in 4 recognizable, central interior 7 umlau fenden, inner edge 3 having. The Süllrand 90 engages like a pin from below into the central interior 7 of the pelvis 1 , making this on the test room floor 50 positioned and prevented from moving horizontally. The Stamp 20 protrudes through the central interior 7 of the container 1 through from the first room 85 in the second room 86 , The weighing plate 10 of the weighing plate 10 and the stamp 20 comprehensive, one-piece stamping punch 30 protrudes over the inner edge 3 of the pelvis 1 and has a hollow cylindrical, concentric with the punch 20 arranged and between the inner 3 and the outer edge 2 down into the basin 1 protruding immersion body 11 on. The immersion body 11 dives along a closed perimeter into one in the basin 1 filled liquid 5 , This creates a dust-tight seal between the top 86 and the lower room 85 ,

The in the basin 1 filled liquid 5 takes a certain, reproducible level of fluid 6 one. A specific, reproducible liquid level 6 in the basin 1 is achieved by putting in the outer edge 3 an overflow opening 4 is arranged. By filling the basin 1 until it overflows over the overflow opening 4 so can always be the same level of fluid 6 to adjust. Alternatively, an overflow opening 4 be waived, as far as in the 1 . 3 and 5 represented, the outer edge 2 is lower than the inner edge 3 ,

As in the 1 . 2 and 5 shown, remains between the immersion body 11 and the inner edge 3 A gap 12 which is sized so small that a labyrinth seal similar blocking effect for liquid flowing through the gap, so that when flushing the pelvis 1 by means of one in the basin 1 directed liquid jet is prevented from rising of the liquid over the inner edge. The gap 12 However, it is again sized so that the occurrence of capillary forces is prevented. To prevent ingress of liquid 5 over the inner edge 3 away and through the inspection room opening 40 through into the lower room 85 to exclude, is the Süllrand 90 higher than inner edge 3 executed. For a between immersion body 11 and inner edge 3 Ascending fluid column thereby creates a sudden, discontinuous cross-sectional enlargement, similar to a Carnot-Borda orifice, whereby a large part of the kinetic energy of the ascending column of liquid is destroyed.

In 2 is to recognize that stamp 20 , Süllrand 90 , inner edge 3 and immersion body 11 are arranged concentrically with each other. Likewise, the between immersion body 11 and inner edge 3 remaining gap 12 to recognize. The Stamp 20 protrudes through from the Süllrand 90 limited test room opening 40 ,

In the 3 and 4 is the basin 1 shown in more detail. Around the bottom of the pool 1 arranged central interior 7 around is the inner edge 3 arranged. The inner edge 3 is higher than the outer edge 2 , The basin 1 Depending on the installation situation, it can have different external dimensions and geometries and can assume, for example, round, square, rectangular or polygonal shapes, but also irregular geometries. For adaptation to a non-horizontal test room floor 50 may be the bottom of the basin 1 obliquely to the horizontal upper edge of the outer edge 2 run. In the outer edge 2 is the overflow opening 4 arranged. The height of the overflow opening above the bottom of the basin 1 determines the liquid level 6 in the basin. Preferably, the pelvis has 1 a sufficiently large, through the outer 2 and inner edge 3 limited liquid surface, allowing level changes of the liquid level 6 in the basin 1 by immersion and immersion of the immersion body 11 of the weighing plate 10 can be neglected. This makes it easy to increase the buoyancy of the liquid 5 dipping part of the weighing pan 10 to determine, since it is sufficient, the vertical displacement of the stamping punch 30 to investigate. A compensation of the buoyancy of the liquid 5 submerged immersion body 11 can be done for example by means of an evaluation, which the vertical displacement of the stamping punch 30 determined and based on the liquid level 6 , the density of the liquid 5 and the geometry of the liquid 5 dipping part of the weighing pan 10 its buoyancy in the liquid 5 determined and adds this force to the display of the force measuring device. The in the basin 1 filled liquid 5 is water, preferably by detergent or detergent relaxed water. Basically, any liquid medium, both in pure form, as well as a solution in the pelvis 1 be filled.

In 5 it can be seen that above the pelvis 1 a second, in the vertical direction substantially flush with the unloaded weighing plate 10 final, removable upper intermediate floor 60 is arranged, which has a cross-sectional shape of the weighing pan 10 corresponding and in the cross-sectional dimensions slightly larger than the weighing plate 10 executed weighing opening 80 having. In the weighing opening 80 is the weighing plate 10 arranged freely movable in the vertical direction.

The upper intermediate floor 60 can be part of the test room floor 50 be, with upper intermediate bottom 60 and test room floor 50 together a double bottom 70 form. The upper, removable false floor 60 and the lower test room floor 50 then together form the test room floor or double floor 70 , Above the upper intermediate floor 60 For example, a transport star can be arranged, which transports pharmaceutical products from test device to test device. In this type of transport, the pharmaceutical products to be tested are placed above the upper intermediate floor 60 pushed. The products are subject to abrasion in the gap of the weighing opening 80 between weighing dish 10 and upper intermediate floor 60 falls. The falling dust from the abrasion falls into the basin 1 and is from the in the basin 1 filled liquid 5 bound.

To prepare for the use of the balance is first with removed weighing plate 10 or, if that is the weighing dish 10 and the stamp 20 comprehensive weighing punch 30 is executed in one piece, with removed weighing punch 30 , the basin 1 on the test room floor 50 positioned by the pelvis 1 with the central interior 7 on the hollow cylindrical pin forming, around the Prüfraumöffnung 40 circumferential Süllrand 90 is set. Then it becomes liquid 5 until the overflow of the pelvis 1 in the basin 1 filled. The basin 1 runs either over the overflow opening 4 over, or provided no overflow opening 4 in the outer edge 2 of the pelvis 1 is arranged over the lower than the inner edge 3 executed outer edge 2 above. By filling until overflowing, the liquid decreases 5 in the basin 1 reproducible always the same liquid level 6 one. Subsequently, the weighing plate 10 on the stamp 20 put on, or the stamping punch 30 with the stamp 20 ahead through the central interior 7 and the inspection room opening 40 inserted through it. The weighing plate 10 dives along a closed perimeter into the liquid 5 one. The one in the liquid 5 dipping part of the weighing plate 10 displaced liquid 5 flows either over the overflow opening 4 or over the outer edge 2 from the pelvis. Subsequently, the test room floor 50 around the pelvis 1 be dried around for example by means of a cloth or by means of a blower. After that, the upper intermediate floor 60 placed on the pelvis. The balance is now ready for operation.

In the case of an intermediate cleaning of the balance, the upper intermediate floor is first of all 60 lifted. After that is the pelvis 1 accessible and can be ejected and rinsed by means of a liquid jet. The gap 12 as well as the higher than the inner edge 3 executed Süllrand 90 Make sure that there is no liquid 5 through the inspection room opening 40 in the first, lower room 85 arrives. Also, the pelvis can 1 taken out and cleaned outside.

For a complete cleaning of the balance, first the upper intermediate floor 60 lifted off the pelvis. Then the weighing plate 10 or the stamping punch 30 decreased. This reduces the level of the liquid 5 below the liquid level 6 off, because the liquid 5 the previously from a part of the weighing pan 10 occupied space can take again. Subsequently, the pelvis 1 with the liquid contained therein 5 without the risk of liquid 5 to shed from the test room floor 50 be removed. Now the test room floor 50 freely accessible for cleaning. The one above the test room floor 50 towering and around the inspection room opening 40 closed circumferential Süllrand 90 Ensures that detergent penetration through the inspection room opening 40 through into the first, lower room 85 is prevented.

7 schematically shows a punch according to a preferred embodiment 30 a balance according to the invention, wherein the weighing punch from the weighing dish 10 and the stamp 20 consists. On the stamp 20 is a dip 11 ' which is placed in the liquid 5 in which the stamp 20 annularly surrounding basin 1 dips and thereby the test room 86 Dustproof against the underlying recording room 85 seals. The immersion body 11 ' and the stamp 20 are preferably arranged coaxially, wherein the punch 20 the immersion body 11 ' protrudes from top to bottom and the immersion body 11 ' the stamp 20 at least dust-tight, preferably also encloses gas and water-tight.

The test room floor 50 forms according to a preferred embodiment of the invention, the boundary between the test room 86 and recording room 85 , The weighing plate 10 preferably closes horizontally in the unloaded position flush with one through the test room 86 extending upper intermediate floor 60 from. The upper intermediate floor 60 preferably serves as a support surface or underlay during transport of the item to be weighed within the test room 86 on the top of the weighing pan 10 , The Stamp 20 extends through the test chamber floor from top to bottom and this for the introduction of force of gravity on the weighing plate 10 aufgelegenden, not shown test object down into a force measuring device, also not shown.

The immersion body 11 ' is in the example of 7 formed as an upside-down bowl, the bottom of the stamp 20 is penetrated and the stamp 20 encloses at least dust-tight. The edge of the bowl dips peripherally around the stamp 20 circulating in the liquid 5 a, eliminating any dust through the immersion body 11 ' , the stamp 20 and the liquid 5 is detained from the test room 86 over the interior 7 in the recording room 85 to get.

According to another embodiment, the immersion body is as a spout, z. B. rubber grommet, or forms like a spout and z. B. frictionally on the stamp 20 postponed.

The immersion body is preferred 11 ' z. B. frictionally or by means of a clamp on the stamp 20 arranged and adjustable in height relative to the height or displaceable, so that the immersion depth of the immersion body 11 ' in the basin 1 can be changed or adjusted to a certain value.

According to a further embodiment, the immersion body is not on the punch 20 but on the weighing plate 30 arranged; in this case, the immersion body 11 preferably designed as a circumferential cylinder jacket, which the weighing plate 30 with its upper end at least dust-tight encloses, from the weighing plate 30 all around the stamp 20 circumferentially protrudes downwards and with its lower end into the liquid 5 dives in (cf. 1 and 5 ).

For safety reasons or to comply with certain statutory safety regulations, it may be necessary to lower the fluid level 6 below a certain minimum level. Therefore shows 8th the basin 1 with the liquid 5 and the test room floor 50 from 7 , wherein the weighing punch 30 , the immersion body 11 ' and the intermediate floor 60 from 7 in 8th are omitted, and being in the basin 1 a lower open, top closed reservoir 15 dips.

The expansion tank 15 is up to a level 6 ' which is above the liquid level 6 lies with the liquid 5 filled and has z. B. the shape of an upside-down bowl or cup-like vessel, the lower edge 16 all around below the liquid level 6 into the liquid 5 dips. If now z. B. due to evaporation, the liquid level 6 down to the height of the edge 16 decreases, it comes automatically to a subsequent flow of liquid 5 from the expansion tank 15 in the basin 1 , causing the liquid level 6 rises again.

Thus, the liquid level 6 do not sink below the height of the edge while in the expansion tank 15 enough liquid 5 located. The height of the edge 16 above the bottom of the basin 1 thus defines a minimum level below which the liquid level can not drop, at least for a long time. The minimum level is chosen so that even if the liquid level 6 has fallen to the level of the minimum level, at each loading condition of the weighing pan 10 , especially with unloaded weighing plate 10 that in the liquid 5 dipping part of the immersion body 11 surrounds the interior peripherally peripherally and thus the dust-tight seal of the test room 86 against the recording room 85 remains guaranteed.

A such embodiment the balance according to the invention is particularly advantageous, even if only temporarily Failure of the dustproof seal must be prevented should, for. B. because the weighing material is toxic.

For safety reasons, a level sensor may further be provided, which triggers an automatic refill and / or an alarm signal when the liquid level 6 falls below the minimum level.

So when filling the liquid 5 in the basin 1 the liquid level 6 the liquid 5 in the basin 5 does not assume a random value but a defined value that can be reproduced at any time, the basin preferably has an overflow opening 4 on (cf. 1 and 5 ). A defined and always exactly reproducible liquid level 6 is particularly advantageous if the buoyant force of the immersion body in the liquid 5 z. B. computationally or mechanically compensated or be squeezed out.

The overflow opening 4 preferably discharges into a collecting vessel, not shown, so that no overflowing liquid on the test chamber floor 50 arrives. The collecting vessel is preferably removable.

The invention relates to a balance z. B. for quality control of pharmaceutical products, preferably comprising one in a receiving space 85 arranged force measuring device as well as a movably arranged in the vertical direction weighing dish 10 and a weighing plate 10 with the force measuring device connecting stamp 20 comprehensive weighing punch 30 in which the weighing plate 10 in one of the recording room 85 separate test room 86 is arranged to be movable in the vertical direction and the punch 20 through one in one the receiving space 85 from the test room 86 separating test room floor 50 arranged test room opening 40 shall pass through.

On the test room floor 50 in the test room 86 in the area of the test chamber opening 40 is a basin 1 arranged, which has an outer edge 2 , as well as one in the bottom of the basin 1 arranged central interior 7 circumferential, inner edge 3 having, wherein the stamp 20 through the central interior 7 of the pelvis 1 through in the test room 86 sticks out and the weighing plate 10 over the inner edge 3 of the pelvis 1 sticks out and along a closed to the inner edge 3 circumferential line in one in the basin 1 filled liquid 5 dips, leaving a dust-tight seal between the test room 86 and the recording room 85 arises, as well as a device for quality control of pharmaceutical products comprising such a balance.

The Invention is particularly in the field of manufacture and operation of quality control devices of pharmaceutical products.

1

pool

2

outer edge

3

internal edge

4

Overflow opening

5

liquid

6

liquid level

6 '

Level in the expansion tank 15

7

inner space

10 100

weighing plate

11 11 '

Submersible body

12

gap

15

surge tank

16

lower edge of 15

20 200

stamp

30 300

cradle temple

40 400

Prüfraumöffnung

50, 500

test chamber

60 600

upper false floor

70 700

duplicate ground

80 800

cradle opening

85

accommodation space

86

testing room

90, 900

Süllrand

Claims (23)

Balance for weighing pharmaceutical or chemical products, comprising - a test room ( 86 ) which passes down through a test chamber floor ( 50 ), - a force measuring device located below the test area ( 86 ) in a recording room ( 85 ), and - a weighing punch arranged above the force measuring device ( 30 ), which at least from a weighing plate ( 10 ) and a stamp ( 20 ), wherein - the weighing plate ( 10 ) in the test room ( 86 ) is arranged and on the top of the weighing plate ( 10 ) the products to be weighed can be placed, - and the stamp ( 20 ) through one in the test room floor ( 50 ) test space opening ( 40 ) down through the test room ( 86 ) in the reception room ( 85 ) and the weight of the weighing on the ( 10 ) introduces products to be weighed into the force measuring device, characterized in that 86 ) on or above the test chamber floor ( 50 ) an open-top, annular basin ( 1 ) is arranged with an outer edge ( 2 ) and an inner edge ( 3 ), which has an upper and lower open, arranged above the Prüfraumöffnung interior ( 7 ) peripherally surrounds, wherein - the pelvis ( 1 ) up to a predetermined liquid level ( 6 ) with a liquid ( 5 ), - the stamp ( 20 ) the interior ( 7 ) protrudes from top to bottom, - and on the stamping punch ( 30 ) an immersion body ( 11 . 11 ' ), which from above into the basin ( 1 ) and the liquid ( 5 ) is immersed and shaped so that the liquid ( 5 ) immersing part of the immersion body ( 11 ) the interior ( 7 ) surrounds peripherally and the interior ( 7 ) and thus also the receiving space ( 85 ) through the immersion body ( 11 . 11 ' ), the stamping punch ( 30 ) and the liquid ( 5 ) dust-proof against the test room ( 86 ) are sealed. Scales according to claim 1, characterized in that the immersion body ( 11 ) as a cylinder jacket ( 11 ) is formed, which of the weighing plate ( 10 ) protrudes downwards. Scales according to claim 1 or 2, characterized in that the immersion body ( 11 . 11 ' ) from the inner edge ( 3 ) through a gap ( 12 ), which is sufficiently narrow to allow for purging of the pelvis (FIG. 1 ) or, in the event of a vibration thereof, an increase of the liquid ( 5 ) in the gap ( 12 ) over the inner edge ( 3 ) to prevent. Scales according to one of the preceding claims, characterized in that the immersion body ( 11 . 11 ' ) from the inner edge ( 3 ) through a gap ( 12 ), which is sufficiently wide, a rise of the liquid due to capillary forces ( 5 ) in the gap ( 12 ) over the inner edge ( 3 ) to prevent. Scales according to one of the preceding claims, characterized in that the outer edge ( 2 ) lower than the inner edge ( 3 ), so that the maximum level of the liquid level ( 6 ) by the height of the outer edge ( 2 ) and an overflow of the pelvis ( 1 ) inwards over the inner edge ( 3 ) is excluded. Balance according to one of the preceding claims, characterized in that in the outer edge ( 2 ) an overflow opening ( 4 ), by which the maximum level of the liquid level ( 6 ) and an overflow of the pelvis ( 1 ) inward over the inner edge ( 3 ) is excluded. Balance according to one of the preceding claims, characterized in that the liquid surface of the basin ( 1 ) is so large that, by increasing the immersion depth of the immersion body ( 11 . 11 ' ) by one millimeter an increase in the liquid level ( 6 ) of less than 0.1 mm, preferably less than 0.01 mm. Scales according to one of the preceding claims, characterized in that the measurement error of the weighing, which by the variable immersion depth of the immersion body ( 11 . 11 ' ) and the associated variable acting on this buoyancy force is caused by a compensation device mechanically or mathematically compensated. Scales according to claim 9, characterized in that the compensation device comprises a computerized device and is capable of controlling the vertical deflection of the immersion body ( 11 . 11 ' ) from a basic position, based on the level of the liquid level ( 6 ), the density of the liquid ( 5 ) and the shape of the immersion body ( 11 . 11 ' ) its buoyancy in the liquid ( 5 ) in dependence on its vertical deflection and to use the thus determined buoyancy force for the computational compensation of the measurement error. Scales according to one of the preceding claims, characterized in that the basin ( 1 ) from the test chamber floor ( 50 ) is removable. Scales according to claim 10, characterized in that on the test chamber floor ( 50 ) around the inspection room opening ( 40 ) circumferential Süllrand ( 90 ) in the form of an interior ( 7 ) of the basin ( 1 ) is arranged engaging hollow cylindrical pin, which the basin ( 1 ) on the test room floor ( 50 ). Scales according to claim 11, characterized in that the Süllrand ( 90 ) is higher than the inner edge ( 3 ) of the basin ( 1 ). Balance according to one of claims 1 to 10, characterized in that the basin ( 1 ) and the test chamber floor ( 50 ) are firmly connected. Scales according to one of the preceding claims, characterized in that above the basin ( 1 ) in a vertical direction substantially flush with the unloaded weighing plate ( 10 ) final, removable intermediate floor ( 60 ), which has a weighing opening ( 80 ), in which the weighing dish ( 10 ) is arranged freely movable in the vertical direction. Scales according to claim 14, characterized in that the upper side of the intermediate floor ( 60 ) flush with the top of the unloaded weighing pan ( 10 ) completes. Scales according to one of the preceding claims, characterized in that the weighing plate ( 10 ) or the punch ( 30 ) is removable. Balance according to one of the preceding claims, characterized in that the weighing punch ( 30 ) integrally formed and thus the weighing plate ( 10 ) not from the stamp ( 20 ) is removable. Balance according to one of the preceding claims, characterized in that the weighing punch ( 30 ) has a mass of 120 to 130 g. Balance according to one of the preceding claims, characterized in that the test room ( 86 ) not only against the recording room ( 85 ), but also dustproof to its entire rest environment. Scales according to one of the preceding claims, characterized by a device ( 15 ), in particular expansion tanks ( 15 ), which indicate a decrease in the liquid level ( 6 ) in the basin ( 1 ) under a predetermined minimum level is able to prevent. Scales according to one of the preceding claims, characterized by a level sensor which, when the liquid level drops ( 6 ) in the basin ( 1 ) is capable of outputting below a predetermined minimum level or below the minimum level of outputting a switching signal or an alarm signal. Use of a balance according to one of the preceding claims in at least a testing device a Device for quality control pharmaceutical products. Scales according to claim 1, characterized in that on the weighing punch ( 30 ) and from above into the basin ( 1 ) and the liquid ( 5 ) submerged immersion bodies ( 11 . 11 ' ) is shaped so that in the liquid ( 5 ) immersing part of the immersion body ( 11 ) at least an upper part of the interior ( 7 ) surrounds peripherally and the interior ( 7 ) and thus also the receiving space ( 85 ) through the immersion body ( 11 . 11 ' ), the stamping punch ( 30 ) and the liquid ( 5 ) dust-proof against the test room ( 86 ) are sealed.