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DE10085481T1 - Neue Zellwand-Anker-Proteine, die aus Hefe stammen, ihre Gene und Zelloberflächen-Expressionssysteme, in denen sie verwendet werden - Google Patents

Neue Zellwand-Anker-Proteine, die aus Hefe stammen, ihre Gene und Zelloberflächen-Expressionssysteme, in denen sie verwendet werden

Info

Publication number
DE10085481T1
DE10085481T1 DE10085481T DE10085481T DE10085481T1 DE 10085481 T1 DE10085481 T1 DE 10085481T1 DE 10085481 T DE10085481 T DE 10085481T DE 10085481 T DE10085481 T DE 10085481T DE 10085481 T1 DE10085481 T1 DE 10085481T1
Authority
DE
Germany
Prior art keywords
yeast
genes
expression systems
surface expression
proteins derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10085481T
Other languages
English (en)
Inventor
Eui-Sung Choi
Jung-Hoon Sohn
So-Young Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Bioscience and Biotechnology KRIBB
Original Assignee
Korea Research Institute of Bioscience and Biotechnology KRIBB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Bioscience and Biotechnology KRIBB filed Critical Korea Research Institute of Bioscience and Biotechnology KRIBB
Publication of DE10085481T1 publication Critical patent/DE10085481T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE10085481T 2000-07-26 2000-07-27 Neue Zellwand-Anker-Proteine, die aus Hefe stammen, ihre Gene und Zelloberflächen-Expressionssysteme, in denen sie verwendet werden Withdrawn DE10085481T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20000042939 2000-07-26
PCT/KR2000/000819 WO2002012509A1 (en) 2000-07-26 2000-07-27 Novel cell wall anchor proteins derived from yeast, genes thereof and cell surface expression systems using the same

Publications (1)

Publication Number Publication Date
DE10085481T1 true DE10085481T1 (de) 2003-07-31

Family

ID=19679978

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10085481T Withdrawn DE10085481T1 (de) 2000-07-26 2000-07-27 Neue Zellwand-Anker-Proteine, die aus Hefe stammen, ihre Gene und Zelloberflächen-Expressionssysteme, in denen sie verwendet werden

Country Status (7)

Country Link
US (1) US7132273B1 (de)
KR (1) KR100395307B1 (de)
CN (1) CN100365125C (de)
AU (1) AU2000261856A1 (de)
DE (1) DE10085481T1 (de)
GB (1) GB2383045A (de)
WO (1) WO2002012509A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100475133B1 (ko) * 2002-09-13 2005-03-10 한국생명공학연구원 효모 표면 발현 벡터를 이용하여 변이 리파제를스크리닝하는 방법 및 신규 변이 리파제
WO2006088328A1 (en) * 2005-02-18 2006-08-24 Cgk Co., Ltd. Detection system for molecular interactions
KR100743973B1 (ko) 2006-04-27 2007-07-30 한국과학기술원 목적단백질 및 코펙터를 재생시키는 효소를 동시에 세포표면에 표면발현시키는 방법
EP2617827A1 (de) 2007-03-26 2013-07-24 Celexion, LLC Zelloberflächenanzeige, Abtastung und Herstellung von Proteinen von Interesse
US8637435B2 (en) * 2007-11-16 2014-01-28 Merck Sharp & Dohme Corp. Eukaryotic cell display systems
US8877686B2 (en) * 2008-03-03 2014-11-04 Glycofi, Inc. Surface display of recombinant proteins in lower eukaryotes
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
CN101717736B (zh) * 2009-10-23 2013-06-19 中国科学院水生生物研究所 一种超高通透性面包酵母及其制备方法
IL210093A0 (en) * 2010-12-19 2011-06-30 David Helman Membrane bound reporter molecules and their use in cell sorting
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
CN102260329B (zh) * 2011-07-29 2013-09-25 华南理工大学 毕赤酵母壁蛋白Gcw45及其表面展示系统和构建方法
WO2013191369A1 (ko) * 2012-06-19 2013-12-27 한국생명공학연구원 ＨｐＧＡＳ1 유전자 파쇄 효모 균주 및 이를 이용한 재조합 단백질의 생산방법
KR101498012B1 (ko) * 2012-06-19 2015-03-11 한국생명공학연구원 ＨｐＧＡＳ1 유전자 파쇄 효모 균주 및 이를 이용한 재조합 단백질의 생산 방법
KR20170003787U (ko) 2016-04-26 2017-11-03 주식회사 스튜디오오겐 안경의 코받침 구조
WO2018041740A1 (en) 2016-09-01 2018-03-08 Bayer Pharma Aktiengesellschaft Non-covalent display system using fimgt/dsf
CN110637085A (zh) * 2017-03-13 2019-12-31 拉勒曼德匈牙利流动性管理有限责任公司 表达细胞相连的异源蛋白的重组酵母宿主细胞
CN108676811B (zh) * 2018-05-28 2021-07-13 郝志敏 一种基因无痕编辑载体及其在生物体基因编辑中的应用
JP2022502081A (ja) * 2018-09-20 2022-01-11 ワシントン・ユニバーシティWashington University 遺伝子操作された微生物ならびにそれを作製および使用する方法
CN110093404A (zh) * 2019-04-16 2019-08-06 艾美汉信疫苗（大连）有限公司 应用荧光实时定量pcr筛选重组汉逊酵母病毒样颗粒表达株的方法
CN110551644A (zh) * 2019-07-19 2019-12-10 天津科技大学 通过调控细胞壁组成蛋白构建的低产高级醇酿酒酵母菌株
CN111996132A (zh) * 2020-07-21 2020-11-27 郑州大学 一种解脂耶氏酵母表面展示方法
CN115232757B (zh) * 2022-06-22 2023-05-23 首都师范大学 酿酒酵母菌株、发酵菌株及其构建方法和生物乙醇生产方法
CN115160417B (zh) * 2022-06-24 2023-06-02 西南大学 盔形毕赤酵母Glyco_hydro类分泌蛋白及其应用
US20240084243A1 (en) * 2022-06-29 2024-03-14 Clara Foods Co. Surface displayed fusion proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741672A (en) * 1984-07-27 1998-04-21 Unilever Patent Holdings B.V. Expression and production of polypeptides using the promoters of the hansenula polymorpha MOX and DAS genes
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5223408A (en) 1991-07-11 1993-06-29 Genentech, Inc. Method for making variant secreted proteins with altered properties
DE69433279T2 (de) * 1993-02-10 2004-07-15 Unilever N.V. Isolierungsverfahren verwendend immobilisierte proteine mit spezifischen bindungskapazitäten
KR100256023B1 (ko) * 1997-10-24 2000-05-01 박호군 한세눌라 폴리모르파용 다중병렬 도입형 발현벡터
CN100338091C (zh) * 1999-09-25 2007-09-19 伊藤火腿株式会社 编码新的融合蛋白的dna和通过该dna的表达来制备有用的多肽的方法

Also Published As

Publication number Publication date
GB2383045A (en) 2003-06-18
US7132273B1 (en) 2006-11-07
GB0301013D0 (en) 2003-02-19
KR20020010428A (ko) 2002-02-04
CN100365125C (zh) 2008-01-30
KR100395307B1 (ko) 2003-09-06
AU2000261856A1 (en) 2002-02-18
CN1454258A (zh) 2003-11-05
WO2002012509A1 (en) 2002-02-14

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Legal Events

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8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee