US2990331A
(en)
|
1956-11-23 |
1961-06-27 |
Pfizer & Co C |
Stable solutions of salts of tetracyclines for parenteral administration
|
US2980584A
(en)
|
1957-10-29 |
1961-04-18 |
Pfizer & Co C |
Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
|
US3062717A
(en)
|
1958-12-11 |
1962-11-06 |
Pfizer & Co C |
Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
|
FR1003M
(fr)
|
1960-03-09 |
1961-12-18 |
Erba Carlo Spa |
Dérivés d'antibiotiques a base de tétracycline.
|
US3165531A
(en)
|
1962-03-08 |
1965-01-12 |
Pfizer & Co C |
13-substituted-6-deoxytetracyclines and process utilizing the same
|
GB1108310A
(en)
|
1964-04-30 |
1968-04-03 |
Pfizer & Co C |
Derivatives of 6-methylene-tetracycline and process for their preparation
|
US3454697A
(en)
|
1965-06-08 |
1969-07-08 |
American Cyanamid Co |
Tetracycline antibiotic compositions for oral use
|
US3304227A
(en)
|
1965-07-15 |
1967-02-14 |
Loyal E Loveless |
Antibiotic-containing animal feed
|
NL6607516A
(el)
|
1966-05-31 |
1967-12-01 |
|
|
DE1767891C3
(de)
|
1968-06-28 |
1980-10-30 |
Pfizer |
Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
|
NL158172B
(nl)
|
1972-09-18 |
1978-10-16 |
Farmaceutici Italia |
Werkwijze voor het bereiden van tetracyclinederivaten met een substituent op de 7-plaats.
|
US3957980A
(en)
|
1972-10-26 |
1976-05-18 |
Pfizer Inc. |
Doxycycline parenteral compositions
|
JPS5119757A
(ja)
|
1974-06-25 |
1976-02-17 |
Farmaceutici Italia |
Arukirutetorasaikurinjudotainoseizoho
|
DE2442829A1
(de)
|
1974-09-06 |
1976-03-18 |
Merck Patent Gmbh |
Tetracyclische verbindungen und verfahren zu ihrer herstellung
|
US4018889A
(en)
|
1976-01-02 |
1977-04-19 |
Pfizer Inc. |
Oxytetracycline compositions
|
US4126680A
(en)
|
1977-04-27 |
1978-11-21 |
Pfizer Inc. |
Tetracycline antibiotic compositions
|
US4806529A
(en)
|
1982-11-18 |
1989-02-21 |
Trustees Of Tufts College, Tufts University |
Tetracycline activity enhancement
|
US5064821A
(en)
|
1982-11-18 |
1991-11-12 |
Trustees Of Tufts College |
Method and compositions for overcoming tetracycline resistance within living cells
|
US5589470A
(en)
|
1990-02-26 |
1996-12-31 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
US4925833A
(en)
|
1983-12-29 |
1990-05-15 |
The Research Foundation Of State University Of New York |
Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis
|
USRE34656E
(en)
|
1983-12-29 |
1994-07-05 |
The Research Foundation Of State University Of New York |
Use of tetracycline to enhance bone protein synthesis and/or treatment of bone deficiency
|
US4704383A
(en)
|
1983-12-29 |
1987-11-03 |
The Research Foundation Of State University Of New York |
Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
|
US4935412A
(en)
|
1983-12-29 |
1990-06-19 |
The Research Foundation Of State University Of New York |
Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
|
US4666897A
(en)
|
1983-12-29 |
1987-05-19 |
Research Foundation Of State University |
Inhibition of mammalian collagenolytic enzymes by tetracyclines
|
US4806372A
(en)
|
1985-02-15 |
1989-02-21 |
Georgia Oil & Gas Co., Inc. |
Nitrite-free-curing of bacon and product thereof
|
US5308839A
(en)
|
1989-12-04 |
1994-05-03 |
The Research Foundation Of State University Of New York |
Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
|
JP3016587B2
(ja)
|
1989-12-04 |
2000-03-06 |
ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク |
非ステロイド抗炎症剤及びテトラサイクリンの配合
|
US5770588A
(en)
|
1991-02-11 |
1998-06-23 |
The Research Foundation Of State University Of New York |
Non-antibacterial tetracycline compositions of the prevention and treatment of root caries
|
US5231017A
(en)
|
1991-05-17 |
1993-07-27 |
Solvay Enzymes, Inc. |
Process for producing ethanol
|
US6756365B2
(en)
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
US5258371A
(en)
|
1992-05-29 |
1993-11-02 |
Kuraray Co., Ltd. |
Method to reduce connective tissue destruction
|
US6043225A
(en)
|
1992-06-12 |
2000-03-28 |
Board Of Regents Of The University Of Washington |
Diagnosis and treatment of arterial chlamydial granuloma
|
DK0599397T3
(da)
|
1992-11-17 |
1996-09-16 |
Univ New York State Res Found |
Tetracycliner, herunder non-mikrobielle, kemisk-modificerede tetracycliner, inhiberer overdreven collagentværbinding ved diabetes
|
US6043231A
(en)
|
1993-03-02 |
2000-03-28 |
The Research Foundation Of State Univ. Of New York |
Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
|
US5523297A
(en)
|
1993-03-02 |
1996-06-04 |
The Research Foundation Of State University Of New York |
Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
|
US5668122A
(en)
|
1993-07-28 |
1997-09-16 |
Fife; Rose S. |
Method to treat cancer with tetracyclines
|
WO1995022529A1
(en)
|
1994-02-17 |
1995-08-24 |
Pfizer Inc. |
9-(substituted amino)-alpha-6-deoxy-5-oxy tetracycline derivatives, their preparation and their use as antibiotics
|
US5843925A
(en)
|
1994-12-13 |
1998-12-01 |
American Cyanamid Company |
Methods for inhibiting angiogenesis, proliferation of endothelial or tumor cells and tumor growth
|
US6165999A
(en)
|
1995-05-03 |
2000-12-26 |
Pfizer Inc |
Tetracycline derivatives
|
US5834449A
(en)
|
1996-06-13 |
1998-11-10 |
The Research Foundation Of State University Of New York |
Treatment of aortic and vascular aneurysms with tetracycline compounds
|
US5827840A
(en)
|
1996-08-01 |
1998-10-27 |
The Research Foundation Of State University Of New York |
Promotion of wound healing by chemically-modified tetracyclines
|
US5789395A
(en)
|
1996-08-30 |
1998-08-04 |
The Research Foundation Of State University Of New York |
Method of using tetracycline compounds for inhibition of endogenous nitric oxide production
|
US5919774A
(en)
|
1996-12-10 |
1999-07-06 |
Eli Lilly And Company |
Pyrroles as sPLA2 inhibitors
|
US5837696A
(en)
|
1997-01-15 |
1998-11-17 |
The Research Foundation Of State University Of New York |
Method of inhibiting cancer growth
|
US5773430A
(en)
|
1997-03-13 |
1998-06-30 |
Research Foundation Of State University Of New York |
Serine proteinase inhibitory activity by hydrophobic tetracycline
|
US5929055A
(en)
|
1997-06-23 |
1999-07-27 |
The Research Foundation Of State University Of New York |
Therapeutic method for management of diabetes mellitus
|
CA2318580A1
(en)
|
1998-01-23 |
1999-07-29 |
Mark L. Nelson |
Pharmaceutically active compounds and methods of use thereof
|
US6277061B1
(en)
|
1998-03-31 |
2001-08-21 |
The Research Foundation Of State University Of New York |
Method of inhibiting membrane-type matrix metalloproteinase
|
US6015804A
(en)
|
1998-09-11 |
2000-01-18 |
The Research Foundation Of State University Of New York |
Method of using tetracycline compounds to enhance interleukin-10 production
|
US5977091A
(en)
|
1998-09-21 |
1999-11-02 |
The Research Foundation Of State University Of New York |
Method of preventing acute lung injury
|
US5998390A
(en)
|
1998-09-28 |
1999-12-07 |
The Research Foundation Of State University Of New York |
Combination of bisphosphonate and tetracycline
|
US6256365B1
(en)
|
1999-08-16 |
2001-07-03 |
Analogic Corporation |
Apparatus and method for reconstruction of images in a computed tomography system using oblique slices
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
DE60027465T2
(de)
|
1999-09-14 |
2007-02-01 |
The Trustees Of Tufts College, Medford |
Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
US6231894B1
(en)
|
1999-10-21 |
2001-05-15 |
Duke University |
Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase
|
JP2003523963A
(ja)
|
2000-01-24 |
2003-08-12 |
トラスティーズ・オブ・タフツ・カレッジ |
クリプトスポリジウム・パルヴム関連疾患の治療のためのテトラサイクリン化合物
|
JP2004505012A
(ja)
|
2000-03-31 |
2004-02-19 |
トラスティーズ・オブ・タフツ・カレッジ |
7−および9−カルバメート、尿素、チオ尿素、チオカルバメート、およびヘテロアリール−アミノ置換テトラサイクリン化合物
|
EP2308863A1
(en)
|
2000-05-15 |
2011-04-13 |
Paratek Pharmaceuticals, Inc. |
7-substituted fused ring tetracycline compounds
|
US20020132798A1
(en)
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
WO2001098236A2
(en)
|
2000-06-16 |
2001-12-27 |
Trustees Of Tufts College |
7-phenyl-substituted tetracycline compounds
|
US20040224927A1
(en)
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
IL153639A0
(en)
|
2000-07-07 |
2003-07-06 |
Tufts College |
9-substituted minocycline compounds
|
US20050143353A1
(en)
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
US7094806B2
(en)
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
HUP0301163A3
(en)
|
2000-07-07 |
2008-08-28 |
Tufts College |
7-substituted tetracycline dervatives, pharmaceutical compositions containing them and their use
|
EP1303479B1
(en)
|
2000-07-07 |
2011-04-06 |
Trustees Of Tufts College |
7-, 8- and 9-substituted tetracycline compounds
|
AU2002250331A1
(en)
|
2001-03-13 |
2002-09-24 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
BR0116935A
(pt)
|
2001-03-13 |
2005-04-12 |
Paratek Pharm Innc |
Composto de tetraciclina, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica
|
EP1241160A1
(en)
|
2001-03-13 |
2002-09-18 |
Glaxo Group Limited |
Tetracycline derivatives and their use as antibiotic agents
|
US7553828B2
(en)
|
2001-03-13 |
2009-06-30 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl substituted minocycline compounds
|
CA2440757A1
(en)
|
2001-03-14 |
2002-09-19 |
Michael Draper |
Substituted tetracycline compounds as synergistic antifungal agents
|
US6841546B2
(en)
|
2001-03-14 |
2005-01-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
US8088820B2
(en)
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
US20060194773A1
(en)
|
2001-07-13 |
2006-08-31 |
Paratek Pharmaceuticals, Inc. |
Tetracyline compounds having target therapeutic activities
|
EP2329828A1
(en)
|
2001-07-13 |
2011-06-08 |
Paratek Pharmaceuticals, Inc. |
Tetracyclines for the treatment of ischaemia
|
WO2003055441A2
(en)
|
2001-08-02 |
2003-07-10 |
Paratek Pharmaceuticals, Inc. |
Medicaments
|
US20030069721A1
(en)
|
2001-09-10 |
2003-04-10 |
Paratek Pharmaceuticals, Inc. |
Computational method for determining oral bioavailability
|
ES2551708T3
(es)
|
2002-01-08 |
2015-11-23 |
Paratek Pharmaceuticals, Inc. |
Compuestos de 4-desdimetilamino tetraciclina
|
EA200802365A1
(ru)
|
2002-03-08 |
2009-08-28 |
Паратек Фармасьютикалс, Инк. |
Аминометилзамещенные тетрациклиновые соединения
|
EP2481723A3
(en)
|
2002-03-21 |
2013-02-13 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
CA2476792A1
(en)
*
|
2002-04-16 |
2003-10-30 |
Collagenex Pharmaceuticals, Inc. |
Methods of simultaneously treating ocular rosacea and acne rosacea
|
EA012136B1
(ru)
|
2002-07-12 |
2009-08-28 |
Пэрэтек Фамэсьютикэлс, Инк. |
Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
|
AU2003287217B2
(en)
|
2002-10-24 |
2010-03-04 |
Paratek Pharmaceuticals, Inc. |
Methods of using substituted tetracycline compounds to modulate RNA
|
WO2004064728A2
(en)
*
|
2003-01-16 |
2004-08-05 |
Paratek Pharmaceuticals, Inc. |
Use of specific tetracycline compounds in therapy
|
WO2004091513A2
(en)
|
2003-04-10 |
2004-10-28 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl substituted minocycline compounds
|
KR101228706B1
(ko)
|
2003-07-09 |
2013-02-01 |
파라테크 파마슈티컬스, 인크. |
치환된 테트라시클린 화합물
|
US20060287283A1
(en)
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
US7786099B2
(en)
|
2004-01-15 |
2010-08-31 |
Paratek Pharmaceuticals, Inc. |
Aromatic a-ring derivatives of tetracycline compounds
|
WO2005082860A1
(en)
|
2004-02-27 |
2005-09-09 |
National Research Council Of Canada |
Tetracyclines and their use as calpain inhibitors
|
US7858601B2
(en)
|
2004-10-25 |
2010-12-28 |
Paratek Pharmaceuticals, Inc. |
4-substituted tetracyclines and methods of use thereof
|
US8466132B2
(en)
*
|
2004-10-25 |
2013-06-18 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
US8088755B2
(en)
|
2005-02-04 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
WO2007014154A2
(en)
*
|
2005-07-21 |
2007-02-01 |
Paratek Pharmaceuticals, Inc. |
10-substituted tetracyclines and methods of use thereof
|
WO2007087416A2
(en)
|
2006-01-24 |
2007-08-02 |
Paratek Pharaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
EP2026776A2
(en)
|
2006-05-15 |
2009-02-25 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
DK2109602T3
(da)
|
2006-12-21 |
2014-05-19 |
Paratek Pharm Innc |
Tetracyclinderivater til behandling af bakterielle, virale og parasitiske infektioner
|
AU2008239606A1
(en)
|
2007-04-12 |
2008-10-23 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
EP2144870A2
(en)
|
2007-04-27 |
2010-01-20 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
CN101784517A
(zh)
|
2007-07-06 |
2010-07-21 |
帕拉特克药品公司 |
合成取代的四环素化合物的方法
|