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CY1121135T1 - Ενωσεις υποκατεστημενης τετρακυκλιnhς για την θεραπευτικη αγωγη φλεγμονωδων διαταραχων του δερματος - Google Patents

Ενωσεις υποκατεστημενης τετρακυκλιnhς για την θεραπευτικη αγωγη φλεγμονωδων διαταραχων του δερματος

Info

Publication number
CY1121135T1
CY1121135T1 CY181101329T CY181101329T CY1121135T1 CY 1121135 T1 CY1121135 T1 CY 1121135T1 CY 181101329 T CY181101329 T CY 181101329T CY 181101329 T CY181101329 T CY 181101329T CY 1121135 T1 CY1121135 T1 CY 1121135T1
Authority
CY
Cyprus
Prior art keywords
treatment
inflammative
cyclines
substituted
compounds
Prior art date
Application number
CY181101329T
Other languages
English (en)
Inventor
Haregewein Assefa
Beena Bhatia
Michael Draper
Laura Honeyman
Dennis P Molnar
Oak K Kim
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Publication of CY1121135T1 publication Critical patent/CY1121135T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/48Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/461,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Περιγράφονται μέθοδοι και συνθέσεις για την θεραπευτική αγωγή διαταραχών του δέρματος (π.χ., ακμή, ροδόχρους ακμή).
CY181101329T 2006-12-21 2018-12-11 Ενωσεις υποκατεστημενης τετρακυκλιnhς για την θεραπευτικη αγωγη φλεγμονωδων διαταραχων του δερματος CY1121135T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87643406P 2006-12-21 2006-12-21
PCT/US2007/026220 WO2008079363A2 (en) 2006-12-21 2007-12-21 Substituted tetracycline compounds for treatment of inflammatory skin disorders

Publications (1)

Publication Number Publication Date
CY1121135T1 true CY1121135T1 (el) 2019-12-11

Family

ID=39432968

Family Applications (1)

Application Number Title Priority Date Filing Date
CY181101329T CY1121135T1 (el) 2006-12-21 2018-12-11 Ενωσεις υποκατεστημενης τετρακυκλιnhς για την θεραπευτικη αγωγη φλεγμονωδων διαταραχων του δερματος

Country Status (13)

Country Link
US (2) US8513223B2 (el)
EP (2) EP3488853A1 (el)
AU (1) AU2007338681B2 (el)
CA (2) CA2892739A1 (el)
CY (1) CY1121135T1 (el)
DK (1) DK2120963T3 (el)
ES (1) ES2701725T3 (el)
LT (1) LT2120963T (el)
PL (1) PL2120963T3 (el)
PT (1) PT2120963T (el)
SI (1) SI2120963T1 (el)
TR (1) TR201818983T4 (el)
WO (1) WO2008079363A2 (el)

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KR20100126469A (ko) 2008-03-05 2010-12-01 파라테크 파마슈티컬스, 인크. 미노사이클린 화합물 및 이들의 사용 방법
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US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
US20130302442A1 (en) * 2012-05-14 2013-11-14 Paratek Pharmaceuticals, Inc. Methods of using (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
BR112017020358A2 (pt) 2015-03-23 2018-07-17 Biopharmx Inc composição farmacêutica de tetraciclina para uso dermatológico
RU2019113715A (ru) 2016-11-01 2020-12-03 Паратек Фармасьютикалс, Инк. 9-аминометилминоциклиновые соединения и их применение для лечениия внебольничной бактериальной пневмонии(вбп)
WO2019016609A1 (en) * 2017-07-21 2019-01-24 Allergan Pharmaceuticals International Limited TREATMENT OF NON-INFLAMMATORY LESIONS
CN110156624B (zh) * 2019-05-29 2022-03-08 河北冀衡药业股份有限公司 一种米诺环素及其衍生物的合成方法

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Also Published As

Publication number Publication date
US8513223B2 (en) 2013-08-20
LT2120963T (lt) 2019-01-10
US20130345179A1 (en) 2013-12-26
AU2007338681A1 (en) 2008-07-03
CA2673486A1 (en) 2008-07-03
CA2892739A1 (en) 2008-07-03
EP2120963B1 (en) 2018-09-12
CA2673486C (en) 2015-09-08
EP2120963A2 (en) 2009-11-25
PT2120963T (pt) 2018-12-17
AU2007338681B2 (en) 2013-09-26
US9481639B2 (en) 2016-11-01
WO2008079363A2 (en) 2008-07-03
EP3488853A1 (en) 2019-05-29
PL2120963T3 (pl) 2019-05-31
WO2008079363A3 (en) 2008-10-02
ES2701725T3 (es) 2019-02-25
SI2120963T1 (sl) 2019-02-28
US20080312193A1 (en) 2008-12-18
DK2120963T3 (en) 2019-01-14
TR201818983T4 (tr) 2019-01-21

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