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CY1113259T1 - Ιμιδαζολυλο διφαινυλο ιμιδαζολια ως αναστολεις ιου ηπατιτιδας c - Google Patents

Ιμιδαζολυλο διφαινυλο ιμιδαζολια ως αναστολεις ιου ηπατιτιδας c

Info

Publication number
CY1113259T1
CY1113259T1 CY20121101023T CY121101023T CY1113259T1 CY 1113259 T1 CY1113259 T1 CY 1113259T1 CY 20121101023 T CY20121101023 T CY 20121101023T CY 121101023 T CY121101023 T CY 121101023T CY 1113259 T1 CY1113259 T1 CY 1113259T1
Authority
CY
Cyprus
Prior art keywords
imidazolia
bisulfonyl
imidazolyl
suspensions
susceptible virus
Prior art date
Application number
CY20121101023T
Other languages
English (en)
Inventor
Carol Bachand
Makonen Belema
Daniel H Deon
Andrew C Good
Jason Goodrich
Clint A James
Rico Lavoie
Omar D Lopez
Alain Martel
Nicholas A Meanwell
Van N Nguyen
Jeffrey Lee Romine
Edward H Ruediger
Lawrence B Snyder
Laurent Denis R St
Fukang Yang
David R Langley
Gan Wang
Lawrence G Hamann
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of CY1113259T1 publication Critical patent/CY1113259T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Η παρούσα αποκάλυψη σχετίζεται με ενώσεις του τύπου (Ι), συνθέσεις και μεθόδους για την αγωγή μολύνσης από ιό ηπατίτιδας C (HCV). Επίσης αποκαλύπτονται φαρμακευτικές συνθέσεις που περιέχουν τέτοιες ενώσεις και μέθοδοι για χρήση των ενώσεων αυτών στην αγωγή HCV-μόλυνσης.
CY20121101023T 2008-02-13 2012-10-26 Ιμιδαζολυλο διφαινυλο ιμιδαζολια ως αναστολεις ιου ηπατιτιδας c CY1113259T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2008/053779 WO2009102325A1 (en) 2008-02-13 2008-02-13 Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors
EP08768910A EP2242752B1 (en) 2008-02-13 2008-02-13 Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
CY1113259T1 true CY1113259T1 (el) 2016-04-13

Family

ID=39661448

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121101023T CY1113259T1 (el) 2008-02-13 2012-10-26 Ιμιδαζολυλο διφαινυλο ιμιδαζολια ως αναστολεις ιου ηπατιτιδας c

Country Status (21)

Country Link
EP (1) EP2242752B1 (el)
JP (1) JP5312486B2 (el)
KR (1) KR101492672B1 (el)
CN (1) CN102007122B (el)
AU (1) AU2008350334B2 (el)
BR (1) BRPI0822323A2 (el)
CA (1) CA2715839C (el)
CY (1) CY1113259T1 (el)
DK (1) DK2242752T3 (el)
EA (1) EA018088B1 (el)
ES (1) ES2391600T3 (el)
HK (1) HK1144194A1 (el)
HR (1) HRP20120706T1 (el)
IL (1) IL207469A (el)
MX (1) MX2010008863A (el)
NZ (1) NZ587557A (el)
PL (1) PL2242752T3 (el)
PT (1) PT2242752E (el)
SI (1) SI2242752T1 (el)
WO (1) WO2009102325A1 (el)
ZA (1) ZA201005573B (el)

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Also Published As

Publication number Publication date
KR20100113629A (ko) 2010-10-21
JP5312486B2 (ja) 2013-10-09
ES2391600T3 (es) 2012-11-28
KR101492672B1 (ko) 2015-02-16
CA2715839A1 (en) 2009-08-20
EA201001274A1 (ru) 2011-06-30
IL207469A (en) 2016-03-31
EP2242752B1 (en) 2012-08-08
CN102007122A (zh) 2011-04-06
WO2009102325A1 (en) 2009-08-20
DK2242752T3 (da) 2012-11-19
EP2242752A1 (en) 2010-10-27
SI2242752T1 (sl) 2013-03-29
PT2242752E (pt) 2012-10-29
BRPI0822323A2 (pt) 2015-06-16
AU2008350334A1 (en) 2009-08-20
HRP20120706T1 (hr) 2012-09-30
AU2008350334B2 (en) 2013-10-17
IL207469A0 (en) 2010-12-30
EA018088B1 (ru) 2013-05-30
NZ587557A (en) 2012-04-27
CA2715839C (en) 2014-12-09
PL2242752T3 (pl) 2012-12-31
MX2010008863A (es) 2010-09-07
JP2011511833A (ja) 2011-04-14
ZA201005573B (en) 2012-01-25
HK1144194A1 (en) 2011-02-02
CN102007122B (zh) 2013-09-04

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