Nothing Special   »   [go: up one dir, main page]

CY1109154T1 - Μικροκαψουλες για την καθυστερημενη και ελεγχομενη απελευθερωση της περινδοπριλης - Google Patents

Μικροκαψουλες για την καθυστερημενη και ελεγχομενη απελευθερωση της περινδοπριλης

Info

Publication number
CY1109154T1
CY1109154T1 CY20091100632T CY091100632T CY1109154T1 CY 1109154 T1 CY1109154 T1 CY 1109154T1 CY 20091100632 T CY20091100632 T CY 20091100632T CY 091100632 T CY091100632 T CY 091100632T CY 1109154 T1 CY1109154 T1 CY 1109154T1
Authority
CY
Cyprus
Prior art keywords
perindopril
delayed
microwaits
liberty
controlled
Prior art date
Application number
CY20091100632T
Other languages
English (en)
Inventor
De Barochez Bruno Huet
Patrick Wutrich
Valérie Legrand
Catherine Castan
Rémi Meyrueix
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of CY1109154T1 publication Critical patent/CY1109154T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε μικροκάψουλες οι οποίες επιτρέπουν την καθυστερημένη και ελεγχόμενη απελευθέρωση της περινδοπρίλης, ή ενός εκ των φαρμακευτικώς αποδεκτών αλάτων της, οι οποίες προορίζονται για χορήγηση από το στόμα.
CY20091100632T 2002-06-24 2009-06-15 Μικροκαψουλες για την καθυστερημενη και ελεγχομενη απελευθερωση της περινδοπριλης CY1109154T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0207778A FR2841140B1 (fr) 2002-06-24 2002-06-24 Microcapsules pour la liberation retardee et controlee du perindopril
EP03760778A EP1515704B1 (fr) 2002-06-24 2003-06-24 Microcapsules pour la liberation retardee et controlee du perindopril

Publications (1)

Publication Number Publication Date
CY1109154T1 true CY1109154T1 (el) 2014-07-02

Family

ID=29719985

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100632T CY1109154T1 (el) 2002-06-24 2009-06-15 Μικροκαψουλες για την καθυστερημενη και ελεγχομενη απελευθερωση της περινδοπριλης

Country Status (37)

Country Link
US (1) US20060165808A1 (el)
EP (1) EP1515704B1 (el)
JP (1) JP4723243B2 (el)
KR (1) KR100722082B1 (el)
CN (1) CN100345541C (el)
AP (1) AP2029A (el)
AR (1) AR040461A1 (el)
AT (1) ATE429214T1 (el)
AU (1) AU2003260620B2 (el)
BR (1) BR0312026A (el)
CA (1) CA2491172C (el)
CR (1) CR7648A (el)
CY (1) CY1109154T1 (el)
DE (1) DE60327318D1 (el)
DK (1) DK1515704T3 (el)
EA (1) EA007571B1 (el)
EC (1) ECSP055570A (el)
ES (1) ES2326218T3 (el)
FR (1) FR2841140B1 (el)
GE (1) GEP20074212B (el)
HR (1) HRP20050055B1 (el)
IL (1) IL165896A0 (el)
IS (1) IS2679B (el)
MA (1) MA27262A1 (el)
ME (1) ME00452B (el)
MX (1) MXPA05000086A (el)
NO (1) NO20050163L (el)
NZ (1) NZ537408A (el)
OA (1) OA12875A (el)
PL (1) PL374377A1 (el)
PT (1) PT1515704E (el)
RS (1) RS50914B (el)
SI (1) SI1515704T1 (el)
TN (1) TNSN04259A1 (el)
UA (1) UA81121C2 (el)
WO (1) WO2004000286A1 (el)
ZA (1) ZA200410333B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
BRPI0615607A2 (pt) * 2005-08-30 2011-05-24 Lek Pharmaceuticals composição farmacêutica compreendendo perindopril ou seus sais
FR2891459B1 (fr) * 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
FR2897865B1 (fr) * 2006-02-28 2008-04-18 Servier Lab Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FI125776B2 (fi) 2008-06-27 2023-07-28 Metsaeliitto Osuuskunta Menetelmä puulevyn käsittelemiseksi
CN106983731A (zh) * 2017-04-20 2017-07-28 上药东英（江苏）药业有限公司 一种培哚普利控释片及其制备方法
DE102018123500A1 (de) 2018-09-25 2020-03-26 Man Energy Solutions Se Vorrichtung und Verfahren zur Einstellung der Länge einer Pleuelstange eines Zylinders einer Brennkraftmaschine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2247186A1 (de) * 1972-09-26 1974-03-28 Bayer Ag Antimykotisches mittel
JPS55129219A (en) * 1979-03-29 1980-10-06 Asahi Chem Ind Co Ltd Slow-releasing preparation
EP2036558A3 (en) * 1993-10-07 2010-04-28 Euro-Celtique S.A. Orally administrable opioid formulations having extended duration of effect
DE19724696A1 (de) 1997-06-12 1998-12-24 Hexal Ag Pharmazeutische Zubereitung mit drei Pelletarten
FR2771010B1 (fr) * 1997-11-19 2003-08-15 Adir Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires
JPH11171769A (ja) * 1997-12-05 1999-06-29 Nichiko Pharmaceutical Co Ltd ３−イソブチリル−２−イソプロピルピラゾロ〔１，５−ａ〕ピリジンの徐放性製剤及びその製法
GB9910773D0 (en) * 1999-05-11 1999-07-07 West Pharm Serv Drug Res Ltd Novel single unit coated dosage forms that can be used to minimise the effect of food on the absorption of drugs from the gastrointestinal tract
AU2001261434A1 (en) * 2000-05-11 2001-11-26 Pharmacia Corporation Aldosterone antagonist composition for release during aldosterone acrophase
BRPI0309142C1 (pt) * 2002-04-09 2021-05-25 Flamel Ireland Ltd suspensão de microcápsulas em uma fase líquida aquosa, que permite a liberação modificada de pelo menos um princípio ativo com exclusão da amoxicilina e que é destinada a ser administrada por via oral
CN1189150C (zh) * 2002-11-07 2005-02-16 张凤英 祛斑美白面膜
CN100389300C (zh) * 2004-01-17 2008-05-21 湖北清江水布垭工程建设公司 大坝面板挠度或坝体内部变形监测方法及装置

Also Published As

Publication number Publication date
DK1515704T3 (da) 2009-07-20
HRP20050055B1 (hr) 2013-11-08
RS50914B (sr) 2010-08-31
SI1515704T1 (sl) 2009-08-31
KR100722082B1 (ko) 2007-05-25
CN100345541C (zh) 2007-10-31
ECSP055570A (es) 2006-04-19
KR20050023337A (ko) 2005-03-09
WO2004000286A1 (fr) 2003-12-31
FR2841140B1 (fr) 2004-10-01
IL165896A0 (en) 2006-01-15
PL374377A1 (en) 2005-10-17
RS112904A (en) 2007-02-05
PT1515704E (pt) 2009-05-20
JP4723243B2 (ja) 2011-07-13
OA12875A (en) 2006-09-15
ZA200410333B (en) 2006-07-26
AU2003260620A1 (en) 2004-01-06
CN1665491A (zh) 2005-09-07
FR2841140A1 (fr) 2003-12-26
AU2003260620B2 (en) 2008-07-31
NO20050163L (no) 2005-01-12
US20060165808A1 (en) 2006-07-27
GEP20074212B (en) 2007-10-10
BR0312026A (pt) 2005-03-22
ATE429214T1 (de) 2009-05-15
JP2005533079A (ja) 2005-11-04
NZ537408A (en) 2006-07-28
UA81121C2 (en) 2007-12-10
TNSN04259A1 (fr) 2007-03-12
ME00452B (me) 2011-10-10
CA2491172A1 (fr) 2003-12-31
AP2004003193A0 (en) 2004-12-31
ES2326218T3 (es) 2009-10-05
IS2679B (is) 2010-09-15
DE60327318D1 (de) 2009-06-04
IS7634A (is) 2005-01-07
EP1515704B1 (fr) 2009-04-22
MXPA05000086A (es) 2005-04-08
AR040461A1 (es) 2005-04-06
AP2029A (en) 2009-08-24
HRP20050055A2 (en) 2005-02-28
CR7648A (es) 2005-07-18
CA2491172C (fr) 2011-02-15
EP1515704A1 (fr) 2005-03-23
EA007571B1 (ru) 2006-12-29
MA27262A1 (fr) 2005-03-01
EA200500030A1 (ru) 2005-06-30

Similar Documents

Publication Publication Date Title
CY1123050T1 (el) Φαρμακα ινδολιδονης για την θεραπεια ή προληψη ινωτικων ασθενειων
CY1109154T1 (el) Μικροκαψουλες για την καθυστερημενη και ελεγχομενη απελευθερωση της περινδοπριλης
CY1121350T1 (el) Απο του στοματος φαρμακοτεχνικες μορφες αναλογων κυτιδινης και μεθοδοι χρησης αυτων
CY1106674T1 (el) Αζαδικυκλικοι ετεροκυκλοι σαν ρυθμιστες υποδοχεα κανναβινοειδους
LTC1608344I2 (lt) Per burną vartojamos kladribino kompozicijos
CY1107383T1 (el) Αναστολεις της φωσφολιπασης α2 του κυτοπλασμικου διαλυματος
CY1113963T1 (el) Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν ανταγωνιστες ακτιβινης-actriia και χρηση αυτων στην προληψη η' θεραπευτικη αγωγη πολλαπλου μυελωματος
CY1106679T1 (el) Αζαδικυκλικες ετεροκυκλικες ενωσεις ως τροποποιητες κανναβινοειδους υποδοχεα
CY1107506T1 (el) Μεθοδος για σταθεροποιηση ενωσεων βενζιμιδαζολης
CY1108625T1 (el) Φαρμακευτικες συνθεσεις για τη χορηγηση απο το στομα ηπαρινης ή παραγωγων της
CY1105655T1 (el) Φαρμακευτικη οροδιασπειρομενη συνθεση περινδοπριλης
CY1107729T1 (el) Φαρμακευτικες συνθεσεις
PT1185253E (pt) Forma de administracao oral para administracao de uma combinacao fixa de tramadol e diclofenac
DE60312736D1 (de) 1,2,4-triaminobenzolderivate zur behandlung von erkrankungen des zentralnervensystems
TNSN06012A1 (en) Emulsifying systems containing azetidine derivatives
CY1112173T1 (el) Η χρηση της cilobradine ή των φαρμακευτικα αποδεκτων αλατων αυτης για την θεραπεια ή την προληψη της καρδιακης ανεπαρκειας
EA200600898A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
EA200501925A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
CY1105699T1 (el) Νεες φαρμακευτικες ενωσεις με αλφα2υποδοχεα δραστηριοτητας
EA200600456A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
EA200600454A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
CY1106540T1 (el) Ετεροκυλικα υποκατεστημενες στη θεση 3 πιπεριδινο-2,6-διονες
AR031972A1 (es) Composicion farmaceutica solida termoformable para la liberacion controlada de perindopril
EA200600250A1 (ru) Новый способ синтеза периндоприла и его фармацевтически приемлемых солей
DE60323470D1 (de) Aminomethyl substituiertes thiazolobenzimidazolderivat