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CY1108597T1 - Συνθεσεις που περιεχουν παραγοντα συνδεσης υποδοχεα οχ-40 ή νουκλεϊνικο οξυ που κωδικοποιει αυτον και μεθοδοι για αυξηση της αντιγονου-ειδικης ανοσοαποκρισης - Google Patents

Συνθεσεις που περιεχουν παραγοντα συνδεσης υποδοχεα οχ-40 ή νουκλεϊνικο οξυ που κωδικοποιει αυτον και μεθοδοι για αυξηση της αντιγονου-ειδικης ανοσοαποκρισης

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Publication number
CY1108597T1
CY1108597T1 CY20081101365T CY081101365T CY1108597T1 CY 1108597 T1 CY1108597 T1 CY 1108597T1 CY 20081101365 T CY20081101365 T CY 20081101365T CY 081101365 T CY081101365 T CY 081101365T CY 1108597 T1 CY1108597 T1 CY 1108597T1
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CY
Cyprus
Prior art keywords
antigen
methods
conducting
code
increasing
Prior art date
Application number
CY20081101365T
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English (en)
Inventor
Andrew D Weinberg
Original Assignee
Sisters Of Providence In Oregon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21845027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1108597(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sisters Of Providence In Oregon filed Critical Sisters Of Providence In Oregon
Publication of CY1108597T1 publication Critical patent/CY1108597T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Αποκαλύπτονται συνθέσεις και μέθοδοι για αύξηση της ανοσοαπόκρισης ενός θηλαστικού προς ένα αντιγόνο με δέσμευση του ΟΧ-40 υποδοχέα επί της επιφάνειας των Τ-κυττάρων, που περιλαμβάνουν χορήγηση σε ένα θηλαστικό μιας σύνθεσης που περιλαμβάνει καθαρισμένο παράγοντα σύνδεσης υποδοχέα ΟΧ-40 και φαρμακευτικώς αποδεκτό φορέα, όπου η εν λόγω σύνθεση χορηγείται στο θηλαστικό, έτσι ώστε ο παράγων σύνδεσης υποδοχέα ΟΧ-40 εμφανίζεται στα Τ-κύτταρα του θηλαστικού κατά τη διάρκεια ή βραχέως μετά την ενεργοποίηση των Τ-κυττάρων από το αντιγόνο. Τέτοιες συνθέσεις και μέθοδοι μπορεί να χρησιμοποιηθούν στην ανοσοποίηση και τη θεραπευτική αγωγή καρκίνου.
CY20081101365T 1998-02-24 2008-11-26 Συνθεσεις που περιεχουν παραγοντα συνδεσης υποδοχεα οχ-40 ή νουκλεϊνικο οξυ που κωδικοποιει αυτον και μεθοδοι για αυξηση της αντιγονου-ειδικης ανοσοαποκρισης CY1108597T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2871698A 1998-02-24 1998-02-24
EP99909562A EP1060247B2 (en) 1998-02-24 1999-02-23 Ox-40 receptor binding agent for use in methods for enhancing tumour antigen-specific immune response

Publications (1)

Publication Number Publication Date
CY1108597T1 true CY1108597T1 (el) 2014-04-09

Family

ID=21845027

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081101365T CY1108597T1 (el) 1998-02-24 2008-11-26 Συνθεσεις που περιεχουν παραγοντα συνδεσης υποδοχεα οχ-40 ή νουκλεϊνικο οξυ που κωδικοποιει αυτον και μεθοδοι για αυξηση της αντιγονου-ειδικης ανοσοαποκρισης

Country Status (12)

Country Link
EP (2) EP1060247B2 (el)
JP (1) JP4741074B2 (el)
AP (1) AP1261A (el)
AT (1) ATE408011T1 (el)
AU (1) AU2873999A (el)
CA (1) CA2321161C (el)
CY (1) CY1108597T1 (el)
DE (1) DE69939526D1 (el)
DK (1) DK1060247T3 (el)
ES (1) ES2315008T5 (el)
PT (1) PT1060247E (el)
WO (1) WO1999042585A1 (el)

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Also Published As

Publication number Publication date
DE69939526D1 (de) 2008-10-23
EP1060247A1 (en) 2000-12-20
EP1997893A1 (en) 2008-12-03
EP1060247B1 (en) 2008-09-10
DK1060247T3 (da) 2009-01-26
EP1060247B2 (en) 2011-10-26
CA2321161C (en) 2011-12-20
JP4741074B2 (ja) 2011-08-03
AP2000001903A0 (en) 2000-09-30
WO1999042585A9 (en) 1999-11-04
ATE408011T1 (de) 2008-09-15
JP2002504334A (ja) 2002-02-12
WO1999042585A1 (en) 1999-08-26
PT1060247E (pt) 2008-12-22
ES2315008T3 (es) 2009-03-16
AU2873999A (en) 1999-09-06
CA2321161A1 (en) 1999-08-26
AP1261A (en) 2004-03-19
ES2315008T5 (es) 2012-03-06

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