Nothing Special   »   [go: up one dir, main page]

CY1107796T1 - Ενωσεις και μεθοδοι για θεραπεια και διαγνωση χλαμυδιακης μολυνσης - Google Patents

Ενωσεις και μεθοδοι για θεραπεια και διαγνωση χλαμυδιακης μολυνσης

Info

Publication number
CY1107796T1
CY1107796T1 CY20071101457T CY071101457T CY1107796T1 CY 1107796 T1 CY1107796 T1 CY 1107796T1 CY 20071101457 T CY20071101457 T CY 20071101457T CY 071101457 T CY071101457 T CY 071101457T CY 1107796 T1 CY1107796 T1 CY 1107796T1
Authority
CY
Cyprus
Prior art keywords
polypeptides
compounds
diagnosis
methods
dna sequences
Prior art date
Application number
CY20071101457T
Other languages
English (en)
Inventor
Steven P Fling
Yasir A W Skeiky
Peter Probst
Ajay Bhatia
Original Assignee
Corixa Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/620,412 external-priority patent/US6448234B1/en
Application filed by Corixa Corporation filed Critical Corixa Corporation
Publication of CY1107796T1 publication Critical patent/CY1107796T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4648—Bacterial antigens
    • A61K39/464835—Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Αποκαλύπτονται ενώσεις και μέθοδοι για τη διάγνωση και θεραπεία Χλαμυδιακής μόλυνσης. Οι ενώσεις που παρέχονται περιλαμβάνουν πολυπεπτίδια, που περιέχουν τουλάχιστον ένα αντιγονικό τμήμα ενός αντιγόνου Chlamydia και DNA αλληλουχίες, που κωδικοποιούν τέτοια πολυπεπτίδια. Παρέχονται επίσης φαρμακευτικές συνθέσεις και εμβόλια, που περιλαμβάνουν τέτοια πολυπεπτίδια ή DNA αλληλουχίες, μαζί με αντισώματα που κατευθύνονται έναντι τέτοιων πολυπεπτιδίων. Διαγνωστικά κιτ, που περιέχουν τέτοια πολυπεπτίδια ή DNA αλληλουχίες και ένα κατάλληλο αντιδραστήριο ανίχνευσης μπορεί να χρησιμοποιηθούν για την ανίχνευση Χλαμυδιακής μόλυνσης σε ασθενείς και σε βιολογικά μείγματα.
CY20071101457T 2000-07-20 2007-11-12 Ενωσεις και μεθοδοι για θεραπεια και διαγνωση χλαμυδιακης μολυνσης CY1107796T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/620,412 US6448234B1 (en) 1998-12-08 2000-07-20 Compounds and methods for treatment and diagnosis of chlamydial infection
US09/841,132 US20020061848A1 (en) 2000-07-20 2001-04-23 Compounds and methods for treatment and diagnosis of chlamydial infection
EP01959114A EP1307564B1 (en) 2000-07-20 2001-07-20 Compounds and methods for treatment and diagnosis of chlamydial infection

Publications (1)

Publication Number Publication Date
CY1107796T1 true CY1107796T1 (el) 2013-06-19

Family

ID=27088713

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101457T CY1107796T1 (el) 2000-07-20 2007-11-12 Ενωσεις και μεθοδοι για θεραπεια και διαγνωση χλαμυδιακης μολυνσης

Country Status (25)

Country Link
US (9) US20020061848A1 (el)
EP (1) EP1307564B1 (el)
JP (1) JP2004513622A (el)
KR (1) KR20030016423A (el)
CN (1) CN100467600C (el)
AT (1) ATE373092T1 (el)
AU (2) AU2001280702B8 (el)
BR (1) BR0112602A (el)
CA (1) CA2418282A1 (el)
CY (1) CY1107796T1 (el)
CZ (1) CZ2003480A3 (el)
DE (1) DE60130468T2 (el)
DK (1) DK1307564T3 (el)
ES (1) ES2294018T3 (el)
HK (1) HK1067381A1 (el)
HU (1) HUP0400477A3 (el)
IL (2) IL153904A0 (el)
MX (1) MXPA03000564A (el)
NO (1) NO20030252L (el)
NZ (3) NZ541013A (el)
PL (1) PL209107B1 (el)
PT (1) PT1307564E (el)
RU (2) RU2410394C2 (el)
WO (1) WO2002008267A2 (el)
ZA (1) ZA200300719B (el)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
EP1105490A1 (en) 1998-08-20 2001-06-13 Aventis Pasteur Limited Nucleic acid molecules encoding inclusion membrane protein c of chlamydia
CA2340283A1 (en) 1998-08-20 2000-03-02 Aventis Pasteur Limited Nucleic acid molecules encoding pomp91a protein of chlamydia
US6686339B1 (en) 1998-08-20 2004-02-03 Aventis Pasteur Limited Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia
US6649370B1 (en) 1998-10-28 2003-11-18 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6607730B1 (en) 1998-11-02 2003-08-19 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding DNA fragments and uses thereof
EP1135501A1 (en) 1998-12-01 2001-09-26 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
ATE469222T1 (de) 1998-12-08 2010-06-15 Corixa Corp Verbindungen und verfahren zur behandlung und diagnose von chlamydia-infektionen
US20080213264A1 (en) * 1998-12-08 2008-09-04 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6555115B1 (en) * 1998-12-08 2003-04-29 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
US7297341B1 (en) 1998-12-23 2007-11-20 Sanofi Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6808713B1 (en) 1998-12-28 2004-10-26 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
EP1140998B1 (en) 1998-12-28 2008-01-23 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
GB9902555D0 (en) 1999-02-05 1999-03-24 Neutec Pharma Plc Medicament
DE60041042D1 (de) 1999-03-12 2009-01-22 Aventis Pasteur Chlamydia antigene und deren korrespondierende dna fragmente und verwendungen davon
WO2000066739A2 (en) 1999-05-03 2000-11-09 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
EP1220925B8 (en) 1999-09-20 2008-04-23 Sanofi Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
US6632663B1 (en) 1999-09-22 2003-10-14 Aventis Pasteur Limited DNA immunization against chlamydia infection
JP4864264B2 (ja) 1999-12-22 2012-02-01 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するｄｎａ断片ならびにその使用
US6919187B2 (en) * 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20030175700A1 (en) 2000-04-21 2003-09-18 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
DE60125350T2 (de) 2000-05-08 2007-07-12 Sanofi Pasteur Ltd., Toronto Chlamydia-antigene, entsprechende dns-fragmente und ihre verwendungen
AU2001276619A1 (en) 2000-07-03 2002-01-14 Chiron S.P.A. Immunisation against chlamydia pneumoniae
US7537772B1 (en) * 2000-10-02 2009-05-26 Emergent Product Development Gaithersburg Inc. Chlamydia protein, gene sequence and the uses thereof
US7731980B2 (en) * 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
US20030059896A1 (en) * 2000-12-21 2003-03-27 Shire Biochem Inc. Novel chlamydia antigens and corresponding DNA fragments
GB2370838A (en) * 2001-01-06 2002-07-10 Benedikt Timmerman Immunogenic complex
CN100515494C (zh) 2001-12-12 2009-07-22 启龙有限公司 抗沙眼衣原体的免疫
GB0203403D0 (en) 2002-02-13 2002-04-03 Chiron Spa Chlamydia cytotoxic-T cell epitopes
EP1635865A2 (en) * 2003-06-26 2006-03-22 Chiron Corporation Immunogenic compositions for chlamydia trachomatis
CA2546840A1 (en) * 2003-11-20 2005-06-02 Sanofi Pasteur Limited Immunization against chlamydia infection
US8541007B2 (en) 2005-03-31 2013-09-24 Glaxosmithkline Biologicals S.A. Vaccines against chlamydial infection
EP1868641A2 (en) * 2005-03-31 2007-12-26 GlaxoSmithKline Biologicals SA Vaccines against chlamydial infection
CN101238146A (zh) * 2005-05-12 2008-08-06 诺华疫苗和诊断有限公司 砂眼衣原体的免疫原性组合物
WO2007030879A1 (en) * 2005-09-13 2007-03-22 Diatech Pty Ltd Diagnostic markers and uses therefor
US9259463B2 (en) * 2006-01-16 2016-02-16 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Chlamydia vaccine
EP1970708A1 (de) * 2007-03-07 2008-09-17 Mikrogen Molekularbiologische Entwicklungs-GmbH Biochip und Verfahren zum selektiven Nachweis von Chlamydia trachomatis-Infektionen
EP2162460A4 (en) * 2007-06-14 2012-06-06 Emergent Product Dev Gaithersburg Inc VACCINES AGAINST CHLAMYDIA INFECTIONS
WO2009020553A2 (en) 2007-08-03 2009-02-12 President And Fellows Of Harvard College Chlamydia antigens
US8637053B2 (en) * 2007-12-03 2014-01-28 President And Fellows Of Harvard College Chlamydia antigens
AU2010220103A1 (en) 2009-03-06 2011-09-22 Novartis Ag Chlamydia antigens
WO2011118496A1 (ja) 2010-03-23 2011-09-29 和光純薬工業株式会社 クラミジア・トラコマティス検出用プライマー及びプローブ、並びにこれを用いたクラミジア・トラコマティスの検出方法
JP2013545448A (ja) * 2010-10-20 2013-12-26 ジェノセア バイオサイエンシーズ， インコーポレイテッド クラミジア抗原及びその使用
US20130095487A1 (en) * 2011-10-18 2013-04-18 University Of South Florida Interferon-Gamma Response as a Diagnostic Test for Persistent Chlamydial Infections
CN107434827B (zh) * 2012-12-05 2020-09-11 生控基因疫苗股份有限公司 用作诱导抗原特异性t细胞反应的免疫原性增强剂的融合蛋白
CN113801191B (zh) * 2021-08-18 2022-05-17 南京大学 一种检测衣原体的多肽探针及其应用

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4118469A (en) * 1976-04-27 1978-10-03 Research Corporation Antigen for trachoma lymphogranuloma venereum (LGV) and non-gonococcal urethritis (NGU)
US4497899A (en) * 1982-04-12 1985-02-05 Abbott Laboratories Immunoassay for Chlamydia trachomatis antigens
US4497900A (en) 1982-04-12 1985-02-05 Abbott Laboratories Immunoassay for Neisseria gonorrhoeae antigens
US4497863A (en) * 1984-03-07 1985-02-05 Milliken Research Corporation Laminated weft insertion fabric
DE3650571T2 (de) 1985-01-14 1997-02-27 Chiron Corp Hauptprotein der Aussenmembran von Chlamydia
US5785973A (en) 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
EP0348725A3 (en) 1988-06-29 1990-10-24 Miles Inc. Species-specific epitode of chlamydia trachomatis and antibodies that recognize the same
CA2047191A1 (en) * 1989-02-17 1990-08-18 Hendrik M. Geysen Method for the use and synthesis of peptides
US5869608A (en) 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
US5166053A (en) * 1990-02-23 1992-11-24 Miles Inc. Specimen adequacy control for chlamydia assays
JP3018553B2 (ja) * 1990-05-08 2000-03-13 日立化成工業株式会社 クラミジア・トラコマティス抗体測定方法及びクラミジア・トラコマティス感染症診断用製剤
US5725863A (en) 1991-09-06 1998-03-10 The United States Of America As Represented By The Secretary Of Agriculture Polypeptides useful in prevention of chlamydia infection
PL170980B1 (pl) * 1992-06-25 1997-02-28 Smithkline Beecham Biolog Szczepionka PL PL PL PL PL PL PL
CA2144882A1 (en) 1992-09-18 1994-03-31 Harlan D. Caldwell Synthetic peptide vaccine for chlamydia trachomatis
US5549978A (en) * 1992-10-30 1996-08-27 Kabushiki Kaisha Toshiba Magnetoresistance effect element
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
WO1996009320A1 (en) 1994-09-20 1996-03-28 Hitachi Chemical Company, Ltd. Antigenic polypeptide of chlamydia pneumoniae
GB9626864D0 (en) 1996-12-24 1997-02-12 Smithkline Beecham Biolog Vaccine
GB9506863D0 (en) 1995-04-03 1995-05-24 Smithkline Beecham Biolog Vaccines
GB9516293D0 (en) 1995-08-09 1995-10-11 Immunova Ltee Novel peptides and their use as vaccines
CN1223589A (zh) * 1996-05-06 1999-07-21 美国拜尔公司 包含鹦鹉热衣原体的猫疫苗及其制备方法
NZ334114A (en) 1996-07-12 2000-06-23 Univ Manitoba DNA immunization against chlamydia infection comprising a major outer membrane protein (MOMP) or a MOMP fragment linked to a promoter sequence
US6464979B1 (en) 1996-09-12 2002-10-15 Aventis Pasteur Limited Chlamydial vaccines and methods of preparation thereof
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
JP4249279B2 (ja) 1997-10-22 2009-04-02 デンカ生研株式会社 クラミジア・トラコマティス主要外膜蛋白質及びその製造方法、並びにクラミジア・トラコマティスの抗体測定方法及び抗体測定試薬
JP2002536958A (ja) 1997-11-21 2002-11-05 ジェンセット Ｃｈｌａｍｙｄｉａｐｎｅｕｍｏｎｉａｅゲノム配列およびポリペプチド、それらのフラグメント、ならびに特に感染症の診断、予防および治療のためのそれらの使用
ATE480625T1 (de) * 1997-11-21 2010-09-15 Merck Serono Biodevelopment Äusseres membranpolypeptid von chlamydia pneumoniae sowie fragmente davon und deren verwendung, insbesondere zur diagnose, prävention und behandlung einer infektion
US7041490B1 (en) * 1997-11-28 2006-05-09 Serono Genetics Institute, S.A. Chlamydia trachomatis polynucleotides and vectors, recombinant host cells, DNA chips or kits containing the same
KR100735652B1 (ko) * 1997-11-28 2007-07-06 세로노 제네틱스 인스티튜트 에스.에이. 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도
CA2326598C (en) 1998-04-07 2014-06-10 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1588714A2 (en) * 1998-10-16 2005-10-26 GlaxoSmithKline Biologicals S.A. Adjuvant systems and vaccines
US6607730B1 (en) * 1998-11-02 2003-08-19 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding DNA fragments and uses thereof
WO2000027994A2 (en) 1998-11-12 2000-05-18 The Regents Of The University Of California Chlamydia pneumoniae genome sequence
US6166177A (en) * 1998-12-08 2000-12-26 Corixa Corporation Compounds and methods for the treatment and diagnosis of chlamydial infection
US6432916B1 (en) * 1998-12-08 2002-08-13 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
ATE469222T1 (de) * 1998-12-08 2010-06-15 Corixa Corp Verbindungen und verfahren zur behandlung und diagnose von chlamydia-infektionen
US6448234B1 (en) * 1998-12-08 2002-09-10 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6565856B1 (en) 1998-12-08 2003-05-20 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6555115B1 (en) * 1998-12-08 2003-04-29 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20080213264A1 (en) * 1998-12-08 2008-09-04 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6447779B1 (en) * 1998-12-08 2002-09-10 Corixa Corporation Compounds for the diagnosis of Chlamydial infection
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
GB9902555D0 (en) 1999-02-05 1999-03-24 Neutec Pharma Plc Medicament
DE60041042D1 (de) 1999-03-12 2009-01-22 Aventis Pasteur Chlamydia antigene und deren korrespondierende dna fragmente und verwendungen davon
WO2000066739A2 (en) 1999-05-03 2000-11-09 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
US6811783B1 (en) 1999-09-07 2004-11-02 Aventis Pasteur Limited Immunogenic compositions for protection against chlamydial infection
EP1220925B8 (en) 1999-09-20 2008-04-23 Sanofi Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
US6632663B1 (en) 1999-09-22 2003-10-14 Aventis Pasteur Limited DNA immunization against chlamydia infection
CA2388461C (en) 1999-09-28 2013-06-11 Infectio Diagnostic (I.D.I.) Inc. Highly conserved genes and their use to generate probes and primers for the detection of microorganisms
CA2384977A1 (en) * 1999-10-14 2001-06-07 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity, high-throughput biological sensors and methods
WO2001035992A1 (en) * 1999-11-19 2001-05-25 Michigan State University Recombinant chlamydia vaccine
JP4864264B2 (ja) 1999-12-22 2012-02-01 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するｄｎａ断片ならびにその使用
US20010048927A1 (en) * 2000-02-01 2001-12-06 Richard Stephens Porin B (PorB) as a therapeutic target for prevention and treatment of infection by chlamydia
US20020146776A1 (en) * 2000-04-21 2002-10-10 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20030175700A1 (en) * 2000-04-21 2003-09-18 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6919187B2 (en) 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
DE60125350T2 (de) 2000-05-08 2007-07-12 Sanofi Pasteur Ltd., Toronto Chlamydia-antigene, entsprechende dns-fragmente und ihre verwendungen
EP1290720A1 (en) * 2000-06-16 2003-03-12 Applied Materials, Inc. Configurable single substrate wet-dry integrated cluster cleaner
AU2001276619A1 (en) 2000-07-03 2002-01-14 Chiron S.P.A. Immunisation against chlamydia pneumoniae
US6827189B2 (en) * 2000-07-20 2004-12-07 Zf Friedrichshafen Ag Electromagnetically actuated, single-surface friction coupling, without a rotor slip ring
US7731980B2 (en) * 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
US7537772B1 (en) * 2000-10-02 2009-05-26 Emergent Product Development Gaithersburg Inc. Chlamydia protein, gene sequence and the uses thereof
GB0103169D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
WO2002079244A2 (en) * 2001-03-30 2002-10-10 University Of Manitoba Chlamydial protease-like activity factor responsible for degradation of host transcription factor
US20030199438A1 (en) * 2001-04-09 2003-10-23 Shaw Allan Christian Method for identification of proteins from intracellular bacteria
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
CN100515494C (zh) * 2001-12-12 2009-07-22 启龙有限公司 抗沙眼衣原体的免疫
US7105171B2 (en) * 2002-03-07 2006-09-12 The Regents Of The University Of California Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
EP1635865A2 (en) * 2003-06-26 2006-03-22 Chiron Corporation Immunogenic compositions for chlamydia trachomatis
FR2869057B1 (fr) * 2004-04-16 2006-06-02 Piscines Desjoyaux Sa Sa Dispositif pour la realisation d'un haut de chainage d'un escalier
ES2389562T3 (es) 2004-10-25 2012-10-29 Statens Seruminstitut Antígenos de Chlamydia trachomatis para uso en vacuna y diagnóstico
US8541007B2 (en) * 2005-03-31 2013-09-24 Glaxosmithkline Biologicals S.A. Vaccines against chlamydial infection
EP1868641A2 (en) 2005-03-31 2007-12-26 GlaxoSmithKline Biologicals SA Vaccines against chlamydial infection
CN101238146A (zh) 2005-05-12 2008-08-06 诺华疫苗和诊断有限公司 砂眼衣原体的免疫原性组合物
EP1976557A2 (en) * 2005-12-22 2008-10-08 Novartis Vaccines and Diagnostics S.r.l. Chlamydial antigens
US9259463B2 (en) * 2006-01-16 2016-02-16 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Chlamydia vaccine
US20080124338A1 (en) * 2006-09-22 2008-05-29 The Scripps Research Institute Methods for treatment of inflammatory disease and chlamydia infectious disease
BRPI0719169A2 (pt) * 2006-10-04 2014-02-04 Glaxosmithkline Biolog Sa Método para o tratamento ou a prevenção de infecção ocular, composição imunogênica, e, uso de uma ou mais proteínas de chlamydia, seus fragmentos imunogênicos ou polinucleotídeos codifocadores de ditas proteínas ou de ditos fragmentos
US7892567B2 (en) * 2007-10-01 2011-02-22 Board Of Regents, The University Of Texas System Methods and compositions for immunization against chlamydial infection and disease
WO2010042206A1 (en) * 2008-10-09 2010-04-15 Board Of Regents, University Of Texas System Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease
JP2012512257A (ja) * 2008-12-17 2012-05-31 ジェノセア バイオサイエンシーズ， インコーポレイテッド クラミジア抗原およびその使用
AU2010220103A1 (en) * 2009-03-06 2011-09-22 Novartis Ag Chlamydia antigens
EP2544715A2 (en) * 2010-03-09 2013-01-16 Board Of Regents, University Of Texas System Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease

Also Published As

Publication number Publication date
DE60130468D1 (de) 2007-10-25
CA2418282A1 (en) 2002-01-31
HUP0400477A3 (en) 2010-01-28
US20080317772A1 (en) 2008-12-25
IL153904A0 (en) 2003-07-31
RU2006120003A (ru) 2007-12-27
ZA200300719B (en) 2004-10-27
EP1307564B1 (en) 2007-09-12
EP1307564A2 (en) 2003-05-07
ES2294018T3 (es) 2008-04-01
MXPA03000564A (es) 2004-12-13
IL153904A (en) 2010-04-29
NO20030252D0 (no) 2003-01-17
US20090028887A1 (en) 2009-01-29
US20120114684A1 (en) 2012-05-10
US20080181918A1 (en) 2008-07-31
US20020061848A1 (en) 2002-05-23
HUP0400477A2 (hu) 2004-05-28
NZ541013A (en) 2007-05-31
RU2003104976A (ru) 2004-07-10
RU2410394C2 (ru) 2011-01-27
NZ549873A (en) 2008-06-30
AU2001280702B8 (en) 2008-02-28
US20110142872A1 (en) 2011-06-16
DE60130468T2 (de) 2008-04-03
WO2002008267A9 (en) 2006-09-28
US20080299142A1 (en) 2008-12-04
NO20030252L (no) 2003-03-14
NZ523628A (en) 2005-08-26
DK1307564T3 (da) 2007-12-27
JP2004513622A (ja) 2004-05-13
US8263089B2 (en) 2012-09-11
PT1307564E (pt) 2007-11-21
US8052975B2 (en) 2011-11-08
KR20030016423A (ko) 2003-02-26
AU2001280702B9 (en) 2002-02-05
WO2002008267A2 (en) 2002-01-31
CN100467600C (zh) 2009-03-11
PL209107B1 (pl) 2011-07-29
HK1067381A1 (en) 2005-04-08
CN1489628A (zh) 2004-04-14
CZ2003480A3 (cs) 2003-09-17
WO2002008267A3 (en) 2003-02-27
BR0112602A (pt) 2004-02-17
ATE373092T1 (de) 2007-09-15
AU2001280702B2 (en) 2008-01-24
US20040234536A1 (en) 2004-11-25
US20090035296A1 (en) 2009-02-05
US7462357B2 (en) 2008-12-09
AU8070201A (en) 2002-02-05
PL365951A1 (en) 2005-01-24

Similar Documents

Publication Publication Date Title
CY1107796T1 (el) Ενωσεις και μεθοδοι για θεραπεια και διαγνωση χλαμυδιακης μολυνσης
NO20012812D0 (no) Forbindelser og fremgangsmåter for behandling og diagnose av chlamydiainfeksjon
HUP0203705A2 (hu) Vegyületek és eljárások Chlamydia-fertőzés kezelésére és diagnózisára
DE60133190D1 (de) Verbindungen und verfahren zur behandlung und diagnose von chlamydia-infektionen
WO2003041560A3 (en) Compounds and methods for treatment and diagnosis of chlamydial infection
CY1114722T1 (el) Αντιγονα στρεπτοκοκκου
WO2000000615A3 (en) Compounds and methods for the diagnosis and treatment of ehrlichia infection
ATE349533T1 (de) Zusammensetzung zur diagnose und behandlung von herpes simplex virusinfektionen
WO2001085949A3 (en) Compounds and methods for the diagnosis and treatment of ehrlichia infection
EP0834567A3 (en) Compounds and methods for the diagnosis and treatment of Babesia microti infection
CY1106349T1 (el) Συστηματα ανιχνευσης ανοσοπροσδιορισμου ιικου αντιγονου ηπατιτιδας c
WO2003020108A3 (en) Compositions and methods for the diagnosis and treatment of herpes simplex virus infection
WO2001085947A3 (en) Compounds and methods for the diagnosis and treatment of babesia microti infection