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CR9115A - REPLACED INDOLES, COMPOSITIONS THAT CONTAIN THEM, MANUFACTURING AND USE PROCEDURE - Google Patents

REPLACED INDOLES, COMPOSITIONS THAT CONTAIN THEM, MANUFACTURING AND USE PROCEDURE

Info

Publication number
CR9115A
CR9115A CR9115A CR9115A CR9115A CR 9115 A CR9115 A CR 9115A CR 9115 A CR9115 A CR 9115A CR 9115 A CR9115 A CR 9115A CR 9115 A CR9115 A CR 9115A
Authority
CR
Costa Rica
Prior art keywords
indoles
compositions
replaced
contain
manufacturing
Prior art date
Application number
CR9115A
Other languages
Spanish (es)
Inventor
Halley Frank
Souaille Catherine
Tabart Michel
Bacque Eric
Viviani Fabrice
Ronan Baptiste
Philippe Letallec Jean
Romme Bruno
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0412966A external-priority patent/FR2878849B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of CR9115A publication Critical patent/CR9115A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00—Racemisation; Complete or partial inversion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invencion se refiere particularmente a la preparacion de indoles sustituidos, a las composiciones que los contienen, a su procedimiento de preparacion, y a su utilizacion como medicamento, en particular como agentes anticancerigenos. Formula (I).The present invention particularly relates to the preparation of substituted indoles, to the compositions containing them, to their preparation process, and to their use as a medicament, in particular as anti-cancer agents. Formula (I).

CR9115A 2004-12-06 2007-05-09 REPLACED INDOLES, COMPOSITIONS THAT CONTAIN THEM, MANUFACTURING AND USE PROCEDURE CR9115A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0412966A FR2878849B1 (en) 2004-12-06 2004-12-06 SUBSTITUTED INDOLES, COMPOSITIONS CONTAINING SAME, METHOD OF MANUFACTURE AND USE
US65046505P 2005-02-07 2005-02-07

Publications (1)

Publication Number Publication Date
CR9115A true CR9115A (en) 2007-10-23

Family

ID=38792212

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9115A CR9115A (en) 2004-12-06 2007-05-09 REPLACED INDOLES, COMPOSITIONS THAT CONTAIN THEM, MANUFACTURING AND USE PROCEDURE

Country Status (9)

Country Link
JP (1) JP2008532926A (en)
KR (1) KR20070100277A (en)
BR (1) BRPI0515811A (en)
CR (1) CR9115A (en)
EA (1) EA012613B1 (en)
IL (1) IL183438A0 (en)
MA (1) MA29026B1 (en)
MX (1) MX2007006764A (en)
NO (1) NO20073015L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005037499A1 (en) * 2005-08-09 2007-02-15 Merck Patent Gmbh pyrazole
WO2020168963A1 (en) * 2019-02-18 2020-08-27 深圳市塔吉瑞生物医药有限公司 Substituted fused aromatic ring derivative, composition and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376529B1 (en) * 1995-06-07 2002-04-23 Peng Cho Tang Mono- and bis-indolylquinones and prophylactic and therapeutic uses thereof
MX9709442A (en) * 1995-06-07 1998-02-28 Sugen Inc Method and compositions for inhibition of adaptor protein/tyrosine kinase interactions.
EP1444204A4 (en) * 2001-10-22 2009-11-04 Univ New York State Res Found Protein kinase and phosphatase inhibitors, methods for designing them, and methods of using them
MY135686A (en) * 2002-06-24 2008-06-30 Schering Corp Indole derivatives useful as histamine h3 antagonists
FR2842526B1 (en) * 2002-07-16 2007-07-13 Aventis Pharma Sa PHARMACEUTICAL COMPOSITIONS COMPRISING A 3-GUANIDINOCARBONYL-1-HETEROARYL-INDOLE DERIVATIVE, PROCESS FOR THE PREPARATION AS MEDICAMENTS
JP2004149429A (en) * 2002-10-29 2004-05-27 Takeda Chem Ind Ltd Indole compound and application thereof

Also Published As

Publication number Publication date
IL183438A0 (en) 2007-09-20
MA29026B1 (en) 2007-11-01
BRPI0515811A (en) 2008-08-05
KR20070100277A (en) 2007-10-10
MX2007006764A (en) 2007-08-15
EA200701227A1 (en) 2007-10-26
NO20073015L (en) 2007-08-28
EA012613B1 (en) 2009-10-30
JP2008532926A (en) 2008-08-21

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