CO6862153A2 - Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv) - Google Patents

Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv)

Info

Publication number: CO6862153A2
Authority: CO; Colombia
Prior art keywords: hcv; hepatitis; infections; virus; treatment
Prior art date: 2011-08-19

Application number

CO14013113A

Other languages

English (en)

Inventor

Pek Yoke Chong

John F Miller

Andrew James Peat

John Brad Shotwell

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-08-19

Filing date

2014-01-23

Publication date

2014-02-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47746761&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6862153(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-01-23 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2014-02-10 Publication of CO6862153A2 publication Critical patent/CO6862153A2/es

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

CO14013113A 2011-08-19 2014-01-23 Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv) CO6862153A2 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201161525440P	2011-08-19	2011-08-19
US201261650681P	2012-05-23	2012-05-23

Publications (1)

Publication Number	Publication Date
CO6862153A2 true CO6862153A2 (es)	2014-02-10

Family

ID=47746761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CO14013113A CO6862153A2 (es)	2011-08-19	2014-01-23	Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv)

Country Status (37)

Country	Link
US (2)	US8927593B2 (es)
EP (2)	EP3199531A1 (es)
JP (2)	JP6367712B2 (es)
KR (1)	KR101913800B1 (es)
CN (1)	CN103732065B (es)
AR (1)	AR087563A1 (es)
AU (1)	AU2012299295B2 (es)
BR (1)	BR112014002845A2 (es)
CA (1)	CA2844086A1 (es)
CL (2)	CL2014000393A1 (es)
CO (1)	CO6862153A2 (es)
CR (1)	CR20140078A (es)
CY (1)	CY1118399T1 (es)
DK (1)	DK2744332T3 (es)
DO (1)	DOP2014000034A (es)
EA (1)	EA032841B1 (es)
ES (1)	ES2611731T3 (es)
HR (1)	HRP20161743T1 (es)
HU (1)	HUE030300T2 (es)
IL (1)	IL230487B (es)
IN (1)	IN2014CN00572A (es)
JO (1)	JO3281B1 (es)
LT (1)	LT2744332T (es)
MA (1)	MA35443B1 (es)
ME (1)	ME02588B (es)
MX (1)	MX354676B (es)
PE (1)	PE20141201A1 (es)
PL (1)	PL2744332T3 (es)
PT (1)	PT2744332T (es)
RS (1)	RS55462B1 (es)
SG (1)	SG10201606883QA (es)
SI (1)	SI2744332T1 (es)
SM (1)	SMT201700028B (es)
TW (1)	TWI538915B (es)
UY (1)	UY34274A (es)
WO (1)	WO2013028371A1 (es)
ZA (1)	ZA201401020B (es)

Families Citing this family (10)

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CN106109479A (zh)	2011-08-17	2016-11-16	葛兰素史克有限责任公司	治疗方法
PL2744332T3 (pl)	2011-08-19	2017-03-31	Glaxo Group Limited	Związki benzofuranowe do leczenia zakażeń wirusem zapalenia wątroby typu C
CN107206089A (zh) *	2014-11-10	2017-09-26	葛兰素史克知识产权第二有限公司	用于丙型肝炎的联合长效组合物和方法
MA40805A (fr) *	2014-11-10	2017-09-20	Glaxosmithkline Ip No 2 Ltd	Compositions pharmaceutiques à action prolongée contre l'hépatite c
KR20180006522A (ko)	2016-07-07	2018-01-18	삼성디스플레이 주식회사	액정 조성물 및 이를 포함하는 액정 표시 장치
US11738088B2 (en)	2016-08-01	2023-08-29	University of Pittsburgh—of the Commonwealth System of Higher Education	Boryl ethers, carbonates, and cyclic acetals as oxidatively-triggered drug delivery vehicles
MX2019010404A (es) *	2017-03-02	2019-11-21	Assembly Biosciences Inc	Compuestos sulfamida cíclicos y métodos de uso de los mismos.
EP3740489A1 (en) *	2018-01-17	2020-11-25	GlaxoSmithKline Intellectual Property Development Limited	Pi4kiiibeta inhibitors
CN114929715A (zh) *	2019-10-25	2022-08-19	住友制药株式会社	新型取代稠环型化合物
CN111026203B (zh) *	2019-12-02	2021-01-26	宁波德晶元科技有限公司	一种适用于真空热水壶的加热控制方法与系统

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EP2251344B2 (en)	2001-01-25	2024-04-24	THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES	Formulation of boronic acid compounds
UA79834C2 (en) *	2002-11-01	2007-07-25	Viropharma Inc	Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
JP2009519240A (ja)	2005-12-01	2009-05-14	ワイス	Ｃ型肝炎ウイルスの感染の治療に有用なアントラニル酸誘導体
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JP2009536660A (ja) *	2006-05-02	2009-10-15	アナコールファーマシューティカルズ，インコーポレイテッド	加水分解耐性ホウ素含有治療剤及びその使用方法
US20070286822A1 (en)	2006-06-12	2007-12-13	Anacor Pharmaceuticals Inc.	Compounds for the Treatment of Periodontal Disease
MX2009013332A (es)	2007-06-08	2010-01-25	Mannkind Corp	Inhibidores de ire-1 alfa.
GB0719366D0 (en) *	2007-10-03	2007-11-14	Smithkline Beecham Corp	Compounds
WO2009111676A2 (en)	2008-03-06	2009-09-11	Anacor Pharmaceuticals, Inc	Boron-containing small molecules as anti-inflammatory agents
CA2714254A1 (en) *	2008-02-14	2009-08-20	F. Hoffmann-La Roche Ag	Heterocyclic antiviral compounds
WO2009137493A1 (en)	2008-05-05	2009-11-12	Wyeth	2-substituted benzofuran compounds to treat infection with hepatitis c virus
WO2009137500A1 (en) *	2008-05-05	2009-11-12	Wyeth	6-substituted benzofuran compounds to treat infection with hepatitis c virus
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AU2011329486A1 (en)	2010-11-18	2013-04-18	Glaxo Group Limited	Compounds
WO2012067663A1 (en)	2010-11-18	2012-05-24	Glaxo Group Limited	Compounds
CN106109479A (zh) *	2011-08-17	2016-11-16	葛兰素史克有限责任公司	治疗方法
WO2013025975A1 (en) *	2011-08-17	2013-02-21	Glaxosmithkline Llc	Combination treatments for hepatitis c
PL2744332T3 (pl)	2011-08-19	2017-03-31	Glaxo Group Limited	Związki benzofuranowe do leczenia zakażeń wirusem zapalenia wątroby typu C

2012
- 2012-08-10 PL PL12826498T patent/PL2744332T3/pl unknown
- 2012-08-10 SI SI201230826A patent/SI2744332T1/sl unknown
- 2012-08-10 EA EA201490213A patent/EA032841B1/ru not_active IP Right Cessation
- 2012-08-10 CA CA2844086A patent/CA2844086A1/en not_active Abandoned
- 2012-08-10 JP JP2014526090A patent/JP6367712B2/ja not_active Expired - Fee Related
- 2012-08-10 RS RS20161131A patent/RS55462B1/sr unknown
- 2012-08-10 MX MX2014001989A patent/MX354676B/es active IP Right Grant
- 2012-08-10 PE PE2014000197A patent/PE20141201A1/es not_active Application Discontinuation
- 2012-08-10 PT PT128264983T patent/PT2744332T/pt unknown
- 2012-08-10 DK DK12826498.3T patent/DK2744332T3/en active
- 2012-08-10 EP EP16195408.6A patent/EP3199531A1/en not_active Withdrawn
- 2012-08-10 HU HUE12826498A patent/HUE030300T2/en unknown
- 2012-08-10 SG SG10201606883QA patent/SG10201606883QA/en unknown
- 2012-08-10 US US13/885,500 patent/US8927593B2/en not_active Expired - Fee Related
- 2012-08-10 BR BR112014002845A patent/BR112014002845A2/pt not_active Application Discontinuation
- 2012-08-10 EP EP12826498.3A patent/EP2744332B1/en active Active
- 2012-08-10 KR KR1020147007196A patent/KR101913800B1/ko active IP Right Grant
- 2012-08-10 ES ES12826498.3T patent/ES2611731T3/es active Active
- 2012-08-10 ME MEP-2016-287A patent/ME02588B/me unknown
- 2012-08-10 AU AU2012299295A patent/AU2012299295B2/en not_active Ceased
- 2012-08-10 IN IN572CHN2014 patent/IN2014CN00572A/en unknown
- 2012-08-10 WO PCT/US2012/050268 patent/WO2013028371A1/en active Application Filing
- 2012-08-10 CN CN201280040219.3A patent/CN103732065B/zh not_active Expired - Fee Related
- 2012-08-10 LT LTEP12826498.3T patent/LT2744332T/lt unknown
- 2012-08-16 AR ARP120103008A patent/AR087563A1/es unknown
- 2012-08-16 JO JOP/2012/0233A patent/JO3281B1/ar active
- 2012-08-17 TW TW101130017A patent/TWI538915B/zh not_active IP Right Cessation
- 2012-08-17 UY UY0001034274A patent/UY34274A/es not_active Application Discontinuation
2014
- 2014-01-16 IL IL230487A patent/IL230487B/en not_active IP Right Cessation
- 2014-01-23 CO CO14013113A patent/CO6862153A2/es active IP Right Grant
- 2014-02-10 ZA ZA201401020A patent/ZA201401020B/en unknown
- 2014-02-17 CL CL2014000393A patent/CL2014000393A1/es unknown
- 2014-02-18 CR CR20140078A patent/CR20140078A/es unknown
- 2014-02-19 DO DO2014000034A patent/DOP2014000034A/es unknown
- 2014-03-13 MA MA36832A patent/MA35443B1/fr unknown
- 2014-11-20 US US14/548,524 patent/US9682999B2/en not_active Expired - Fee Related
2016
- 2016-12-19 HR HRP20161743TT patent/HRP20161743T1/hr unknown
- 2016-12-22 JP JP2016249387A patent/JP2017125010A/ja active Pending
- 2016-12-27 CY CY20161101345T patent/CY1118399T1/el unknown
2017
- 2017-01-18 SM SM201700028T patent/SMT201700028B/it unknown
- 2017-02-03 CL CL2017000293A patent/CL2017000293A1/es unknown

Also Published As

Publication number	Publication date
HRP20161743T1 (hr)	2017-02-24
EA201490213A1 (ru)	2014-07-30
JO3281B1 (ar)	2018-09-16
EP2744332A4 (en)	2015-01-14
JP2017125010A (ja)	2017-07-20
JP6367712B2 (ja)	2018-08-01
BR112014002845A2 (pt)	2017-02-21
AU2012299295A1 (en)	2014-02-20
LT2744332T (lt)	2017-01-10
SI2744332T1 (sl)	2017-01-31
EP3199531A1 (en)	2017-08-02
IL230487A0 (en)	2014-03-31
IN2014CN00572A (es)	2015-04-03
PT2744332T (pt)	2017-01-24
DOP2014000034A (es)	2014-06-01
DK2744332T3 (en)	2017-01-16
EP2744332B1 (en)	2016-10-26
MX2014001989A (es)	2014-02-27
UY34274A (es)	2013-04-05
PE20141201A1 (es)	2014-10-03
CN103732065B (zh)	2016-10-26
CL2014000393A1 (es)	2014-08-01
EA032841B1 (ru)	2019-07-31
PL2744332T3 (pl)	2017-03-31
JP2014527529A (ja)	2014-10-16
US20130237501A1 (en)	2013-09-12
US20150080343A1 (en)	2015-03-19
CR20140078A (es)	2014-03-20
KR20140054287A (ko)	2014-05-08
US9682999B2 (en)	2017-06-20
ES2611731T3 (es)	2017-05-10
CL2017000293A1 (es)	2017-10-06
CN103732065A (zh)	2014-04-16
EP2744332A1 (en)	2014-06-25
KR101913800B1 (ko)	2018-11-01
ME02588B (me)	2017-06-20
SG10201606883QA (en)	2016-10-28
AU2012299295B2 (en)	2016-03-31
ZA201401020B (en)	2020-11-25
TW201321390A (zh)	2013-06-01
WO2013028371A1 (en)	2013-02-28
RS55462B1 (sr)	2017-04-28
MA35443B1 (fr)	2014-09-01
IL230487B (en)	2019-06-30
SMT201700028B (it)	2017-03-08
MX354676B (es)	2018-03-15
HUE030300T2 (en)	2017-04-28
AR087563A1 (es)	2014-04-03
CY1118399T1 (el)	2017-06-28
US8927593B2 (en)	2015-01-06
CA2844086A1 (en)	2013-02-28
TWI538915B (zh)	2016-06-21

Publication	Publication Date	Title
CO6862153A2 (es)	2014-02-10	Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv)
SMT201600325B (it)	2016-11-10	Alifani, ciclofani, eterafani, eterofani, etero-eterafani e metalloceni sostituiti utili per il trattamento di infezioni da hcv
CL2015000482A1 (es)	2015-07-10	Compuestos derivado de 6-aminoacido-heteriarildihidropirimidinas; proceso de obtención; composicion farmaceutica; y su uso para el tratamiento o profilaxis de la infección por el virus de la hepatitis b
DK3590928T3 (da)	2021-08-30	Pyrimidinderivater til behandling af virusinfektioner
CL2013001428A1 (es)	2014-06-27	Compuesto que inhibe la actividad del virus de la hepatitis c (hcv); composición farmacéutica que comprende el compuesto; método de tratamiento de hepatitis c.
CL2015000925A1 (es)	2015-08-28	Compuestos derivados de heterociclos nitrogenados; composicion farmaceutica; un metodo para tratar infecciones viricas provocadas por virus sincicial respiratorio (vsr)
HK1211589A1 (en)	2016-05-27	Compounds for the treatment of paramoxyvirus viral infections
DK2958900T3 (da)	2019-07-01	2-aminopyrimidinderivater til behandling af virusinfektioner
CR20140177A (es)	2014-08-18	Métodos para el tratamiento de vhc
DK3520805T3 (da)	2021-04-19	Sammensætninger til behandling af myelofibrose
CO6821947A2 (es)	2013-12-31	Inhibidores del virus de la hepatitis c
CO6940424A2 (es)	2014-05-09	Inhibidores del virus de la hepatitis c
BR112013012998A2 (pt)	2016-09-13	compostos para tratar infecções por vírus sincicial respiratório
CO6821952A2 (es)	2013-12-31	Inihibidores del virus de la hepatitis c
BRPI0807222A2 (pt)	2014-04-29	Análogos de neucleosídeo para tratamento de infecções virais
CR20130171A (es)	2013-07-24	Composición vacunal para el control de las infestaciones por ectoparasitos
CL2014000394A1 (es)	2014-08-01	Uso de compuestos fenil-benzofuran-sulfamido sustituidos para el tratamiento del virus de la hepatitis c (hcv); y composicion farmaceutica que comprende a estos compuestos fenil-benzofuran-sulfamido sustituidos.
DK2939665T3 (da)	2019-06-11	Farmaceutisk sammensætning til behandling af hiv-infektioner
EP2900656A4 (en)	2016-03-02	SPIRRING COMPOUNDS AS HEPATITIS C-VIRUS (HCV) INHIBITORS
DK2723336T3 (da)	2020-06-29	Sammensætninger til behandling af fragilt X-syndrom
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