CO4940439A1 - COMPOUNDS 4-AMINO-6,7-DISSTITUTED-PIRIDO- [2,3-d] PIRIMI- DINA - Google Patents
COMPOUNDS 4-AMINO-6,7-DISSTITUTED-PIRIDO- [2,3-d] PIRIMI- DINAInfo
- Publication number
- CO4940439A1 CO4940439A1 CO98020309A CO98020309A CO4940439A1 CO 4940439 A1 CO4940439 A1 CO 4940439A1 CO 98020309 A CO98020309 A CO 98020309A CO 98020309 A CO98020309 A CO 98020309A CO 4940439 A1 CO4940439 A1 CO 4940439A1
- Authority
- CO
- Colombia
- Prior art keywords
- disstituted
- pirido
- pirimi
- dina
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto y sales y amidas de él farmacéuticamente aceptablesque tienen la fórmulaen dondeR1 y R2 son independientemente H, alquilo C1 -C6 , aralquilo o acilo o pueden tomarse juntos con el átomo de nitrógeno al cual están unidos paraformar un anillo de 5- a 7- miembros que opcionalmente contienen de 1 átomo de oxígeno o nitrógeno adicional; R3 y R4 son independientemente seleccionados de un alquilo C1 -C6 , alquenilo C2 -C6 , alquinilo C2 -C6 , arilo, arilalquilo, heteroarilo o un grupo heterocíclico y las líneas punteadas indican que un doble enlace está opcionalmente presente.A pharmaceutically acceptable compound and salts and amides thereof having the formula wherein R 1 and R 2 are independently H, C 1 -C 6 -alkyl, aralkyl or acyl or may be taken together with the nitrogen atom to which they are attached to form a 5- to 7-ring members optionally containing 1 additional oxygen or nitrogen atom; R3 and R4 are independently selected from a C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, aryl, arylalkyl, heteroaryl or a heterocyclic group and the dotted lines indicate that a double bond is optionally present.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83439397A | 1997-04-16 | 1997-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4940439A1 true CO4940439A1 (en) | 2000-07-24 |
Family
ID=25266829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO98020309A CO4940439A1 (en) | 1997-04-16 | 1998-04-14 | COMPOUNDS 4-AMINO-6,7-DISSTITUTED-PIRIDO- [2,3-d] PIRIMI- DINA |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0979230A1 (en) |
| JP (1) | JP2001520649A (en) |
| KR (1) | KR20010006453A (en) |
| CN (1) | CN1259948A (en) |
| AR (1) | AR012435A1 (en) |
| AU (1) | AU744528B2 (en) |
| BG (1) | BG103861A (en) |
| BR (1) | BR9809088A (en) |
| CA (1) | CA2287465A1 (en) |
| CO (1) | CO4940439A1 (en) |
| HU (1) | HUP0001402A3 (en) |
| IL (1) | IL131892A0 (en) |
| NO (1) | NO995033L (en) |
| NZ (1) | NZ337844A (en) |
| PL (1) | PL336262A1 (en) |
| SK (1) | SK142099A3 (en) |
| TR (1) | TR199902456T2 (en) |
| TW (1) | TW458977B (en) |
| WO (1) | WO1998046603A1 (en) |
| ZA (1) | ZA982912B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001057040A1 (en) * | 2000-02-03 | 2001-08-09 | Abbott Laboratories | 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
| ATE305303T1 (en) * | 2001-02-12 | 2005-10-15 | Hoffmann La Roche | 6-SUBSTITUTED PYRIDOPYRIMIDINES |
| US20090209492A1 (en) | 2004-11-12 | 2009-08-20 | Trustees Of Tufts College | Lipase Inhibitors |
| US20100063032A1 (en) * | 2007-03-28 | 2010-03-11 | Debenham John S | Substituted pyrido[2,3-d]pyrimidine derivatives as cannabinoid-1 receptor modulators |
| WO2014055955A1 (en) * | 2012-10-05 | 2014-04-10 | Rigel Pharmaceuticals, Inc. | Gdf-8 inhibitors |
| WO2017205848A1 (en) * | 2016-05-27 | 2017-11-30 | Legacy Emanuel Hospital & Health Center | Methanocarba derivatives of pseudoribose that inhibit adenosine kinase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB774094A (en) * | 1953-01-02 | 1957-05-08 | Wellcome Found | Improvements in or relating to pyrimidine compounds |
| IL112249A (en) * | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
-
1998
- 1998-03-27 TW TW087104674A patent/TW458977B/en not_active IP Right Cessation
- 1998-04-06 ZA ZA982912A patent/ZA982912B/en unknown
- 1998-04-14 CO CO98020309A patent/CO4940439A1/en unknown
- 1998-04-15 AR ARP980101732A patent/AR012435A1/en unknown
- 1998-04-16 IL IL13189298A patent/IL131892A0/en unknown
- 1998-04-16 PL PL98336262A patent/PL336262A1/en unknown
- 1998-04-16 NZ NZ337844A patent/NZ337844A/en unknown
- 1998-04-16 CA CA002287465A patent/CA2287465A1/en not_active Abandoned
- 1998-04-16 TR TR1999/02456T patent/TR199902456T2/en unknown
- 1998-04-16 EP EP98917950A patent/EP0979230A1/en not_active Withdrawn
- 1998-04-16 JP JP54387898A patent/JP2001520649A/en active Pending
- 1998-04-16 WO PCT/US1998/004127 patent/WO1998046603A1/en not_active Application Discontinuation
- 1998-04-16 KR KR1019997009543A patent/KR20010006453A/en not_active Application Discontinuation
- 1998-04-16 SK SK1420-99A patent/SK142099A3/en unknown
- 1998-04-16 HU HU0001402A patent/HUP0001402A3/en unknown
- 1998-04-16 CN CN98806072A patent/CN1259948A/en active Pending
- 1998-04-16 AU AU70981/98A patent/AU744528B2/en not_active Ceased
- 1998-04-16 BR BR9809088-7A patent/BR9809088A/en not_active IP Right Cessation
-
1999
- 1999-10-15 NO NO995033A patent/NO995033L/en not_active Application Discontinuation
- 1999-11-05 BG BG103861A patent/BG103861A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010006453A (en) | 2001-01-26 |
| AU7098198A (en) | 1998-11-11 |
| AU744528B2 (en) | 2002-02-28 |
| TR199902456T2 (en) | 2000-07-21 |
| WO1998046603A1 (en) | 1998-10-22 |
| HUP0001402A2 (en) | 2000-10-28 |
| AR012435A1 (en) | 2000-10-18 |
| CN1259948A (en) | 2000-07-12 |
| NZ337844A (en) | 2001-11-30 |
| SK142099A3 (en) | 2000-05-16 |
| NO995033D0 (en) | 1999-10-15 |
| CA2287465A1 (en) | 1998-10-22 |
| ZA982912B (en) | 1998-10-09 |
| EP0979230A1 (en) | 2000-02-16 |
| BG103861A (en) | 2000-06-30 |
| BR9809088A (en) | 2000-08-01 |
| HUP0001402A3 (en) | 2001-01-29 |
| JP2001520649A (en) | 2001-10-30 |
| NO995033L (en) | 1999-12-15 |
| IL131892A0 (en) | 2001-03-19 |
| PL336262A1 (en) | 2000-06-19 |
| TW458977B (en) | 2001-10-11 |
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