CN220878925U

CN220878925U - Micro-liquid dispensing device

Info

Publication number: CN220878925U
Application number: CN202322636069.0U
Authority: CN
Inventors: 费敏; 曹亦峰; 卢楷烨; 请求不公布姓名
Original assignee: Suzhou Shuda Innovative Medical Technology Co ltd; Suzhou University
Current assignee: Suzhou Shuda Innovative Medical Technology Co ltd; Suzhou University
Priority date: 2023-09-27
Filing date: 2023-09-27
Publication date: 2024-05-03
Anticipated expiration: 2033-09-27

Abstract

The utility model discloses a micro liquid dispensing device which comprises a sample tube, a sealing plug, a liquid separating mechanism, a conical tube, a first control valve, a second control valve, a screw pushing and injecting mechanism and the like. The sealing plug is used for sealing an opening part formed in the upper part of the sample tube, the liquid separating mechanism comprises a liquid storage cavity, a first liquid flow channel and a second liquid flow channel, the liquid storage cavity is respectively communicated with the inner cavity of the sample tube and the conical tube through the first liquid flow channel and the second liquid flow channel, and the screw pushing and injecting mechanism is used for driving liquid in the liquid storage cavity to enter the conical tube in a screw pushing and injecting mode. The first control valve and the second control valve are respectively used for controlling the conduction and the blocking of the first liquid flow channel and the second liquid flow channel. The micro-liquid distribution device has the advantages of simple structure, convenient use and easy mass production, can be used for rapidly and accurately distributing micro-liquid and can prevent the liquid from being polluted by the environment.

Description

Micro-liquid dispensing device

Technical Field

The utility model particularly relates to a micro-liquid distribution device, and belongs to the technical field of liquid quantitative distribution.

Background

At present, in the fields of biology, chemistry and the like, detection and analysis of micro-liter or nano-scale micro-liquid are often required. In the process, if the trace liquid cannot be rapidly and accurately separated, the detection efficiency and the accuracy of the detection result are greatly affected. The traditional trace liquid sample separation is mainly completed manually by operators through equipment such as a high-precision pipetting gun, and the like, and has the advantages of high cost, low efficiency and easy error. For this reason, many researchers in the industry have proposed various improvements. For example, researchers have proposed an automated microliter liquid dosing device that includes: a fluid channel module, a drive module, and a fluid derivation module; the fluid channel module is provided with a first inflow channel, a quantitative chamber and an outflow channel, and the first inflow channel, the quantitative chamber and the outflow channel are communicated; the first inflow channel is provided with a first fluid inlet valve, and the outflow channel is internally provided with a first fluid push-out valve; a quantitative push rod is movably arranged in the quantitative cavity; the driving module is used for controlling the working states of the first fluid guide valve, the first fluid push valve and the quantitative push rod; the fluid guiding-out module is arranged at one end of the outflow channel far away from the fluid pushing-out valve so as to receive the sample flowing out of the outflow channel. Compared with the traditional micro-liquid dispensing mode, the automatic micro-liter liquid quantitative dispensing device can remarkably improve the liquid dispensing efficiency and eliminate the interference of human factors, but has the defects that samples are easy to be polluted by aerosol in the environment in the liquid dispensing process, and the accuracy of liquid dispensing is still to be improved.

Disclosure of Invention

To overcome the deficiencies of the prior art, the present utility model provides a micro-fluid dispensing device comprising: the device comprises a sample tube, a sealing plug, a liquid separation mechanism, a conical tube, a first control valve, a second control valve and a screw pushing and injecting mechanism;

the upper part of the sample tube is provided with an opening part, and the sealing plug is used for sealing the opening part and isolating the inner cavity of the sample tube from the external environment;

The liquid separation mechanism comprises a liquid storage cavity, a first liquid flow channel and a second liquid flow channel, and the liquid storage cavity is communicated with the inner cavity of the sample tube and the conical tube through the first liquid flow channel and the second liquid flow channel respectively;

the screw pushing and injecting mechanism is movably matched with the liquid separating mechanism and is used for driving liquid in the liquid storage cavity to enter the conical tube in a screw pushing and injecting mode;

The sample tube, the first control valve, the second control valve and the conical tube are respectively connected with the liquid separating mechanism, wherein the first control valve is used for controlling the conduction and the blocking of the first liquid flow channel, and the second control valve is used for controlling the conduction and the blocking of the second liquid flow channel.

In one embodiment, the opening is provided at the upper end of the sample tube, and the sealing plug is at least partially embedded in the opening, so as to seal the opening.

In one embodiment, a first clamping mechanism and an infusion hole are arranged on the outer wall of one side of the sample tube, a second clamping mechanism is arranged on the outer wall of one side of the liquid separating mechanism, and when the first clamping mechanism is fixedly clamped with the second clamping mechanism, the infusion hole is connected with the first liquid flow channel, so that the inner cavity of the sample tube is communicated with the liquid storage cavity.

In one embodiment, the first clamping mechanism comprises a first groove and a first bump which are arranged on the outer wall of one side of the sample tube at intervals, one end opening of the transfusion hole is arranged on the bottom surface of the first groove, and the other end opening is exposed in the inner cavity of the sample tube; the second clamping mechanism comprises a second groove and a second bump which are arranged on the outer wall of one side of the liquid separating mechanism at intervals, one end opening of the first liquid flow channel is arranged on the top end surface of the second bump, and the other end opening of the first liquid flow channel is connected with the liquid storage cavity; the second lug is used for being clamped with the first groove to form a sealing structure, and the second groove is used for being clamped with the first lug.

In one embodiment, the first clamping mechanism is integrally provided with the sample tube.

In one embodiment, the second clamping mechanism is integrally provided with the liquid separating mechanism.

In one embodiment, the first flow channel and the second flow channel are interdigitated.

In one embodiment, the axis of the first control valve is perpendicular to the axis of the second control valve.

In one embodiment, the liquid separating mechanism is further provided with a first valve hole, the first valve hole is arranged in a crossing manner with the first liquid flow channel, the first control valve is at least partially movably arranged in the first valve hole, and the conduction and blocking of the first liquid flow channel are realized by driving the first control valve to rotate around the axis of the first control valve and/or move along the axis of the first valve hole.

In one embodiment, the liquid separating mechanism is further provided with a second valve hole, the second valve hole is arranged in a crossing manner with the second liquid flow channel, the second control valve is at least partially movably arranged in the second valve hole and can move along the axial direction of the second valve hole, and the conduction and blocking of the second liquid flow channel are realized by driving the second control valve to move along the axial direction of the second valve hole.

In one embodiment, the second control valve comprises a valve body and two annular sealing sleeves, the valve body comprises a first annular protruding part, a second annular protruding part, a third annular protruding part and an annular concave lower part, the first annular protruding part, the annular concave lower part and the third annular protruding part are sequentially arranged along the axis of the valve body, the second annular protruding part is arranged in the annular concave lower part, the diameter of the second annular protruding part is smaller than that of the first annular protruding part, the two annular sealing sleeves are sleeved at the annular concave lower part and distributed on two sides of the second annular protruding part, the outer walls of the annular sealing sleeves are flush with the first annular protruding part and the third annular protruding part, when the second annular protruding part reaches the crossing position of the second liquid flow channel, the second liquid flow channel is conducted, and when any annular sealing sleeve reaches the crossing position of the second liquid flow channel, the second liquid flow channel is blocked.

In one embodiment, the valve body further comprises a plurality of point-shaped bulges which are discretely distributed in the annular concave lower part, the height of the point-shaped bulges along the radial direction of the valve body is smaller than that of the first annular bulge along the radial direction of the valve body, and a plurality of point-shaped grooves are distributed on the inner wall of the annular sealing sleeve, and each point-shaped groove is matched with a corresponding point-shaped bulge.

In one embodiment, the conical tube is removably coupled to the dispensing mechanism.

Compared with the prior art, the micro liquid distribution device provided by the utility model has the advantages of simple structure, convenience in use and easiness in large-scale low-cost production, can be used for rapidly and accurately distributing micro liquid, can effectively prevent the liquid from being polluted by the environment, and improves the accuracy of biological/chemical detection results.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the utility model.

FIG. 1 is a schematic perspective view of a micro-fluid dispensing device according to an embodiment of the present utility model;

FIG. 2 is a schematic cross-sectional view of the micro-fluid dispensing device of FIG. 1;

FIG. 3 is a schematic perspective view of a sample tube according to an embodiment of the present utility model;

FIG. 4 is a schematic cross-sectional view of a sample tube according to an embodiment of the present utility model;

fig. 5 is a schematic perspective view of a sealing plug according to an embodiment of the present utility model;

FIG. 6 is a schematic perspective view of a second control valve according to an embodiment of the present utility model;

FIG. 7 is a schematic perspective view of a liquid separating mechanism according to an embodiment of the present utility model;

FIG. 8 is a schematic cross-sectional view of a liquid separating mechanism according to an embodiment of the present utility model;

FIG. 9 is a schematic perspective view of a screw injection mechanism according to an embodiment of the present utility model;

FIG. 10 is a schematic cross-sectional view of a screw injection mechanism according to an embodiment of the present utility model;

FIG. 11 is a schematic perspective view of a first conical tube according to an embodiment of the present utility model;

FIG. 12 is a schematic cross-sectional view of a first conical tube according to an embodiment of the present utility model;

FIG. 13 is a schematic perspective view of a second type of tapered tube according to an embodiment of the present utility model;

FIG. 14 is a schematic cross-sectional view of a second type of tapered tube according to an embodiment of the present utility model.

Detailed Description

Other advantages and effects of the present utility model will become apparent to those skilled in the art from the following disclosure, which describes the embodiments of the present utility model with reference to specific examples. The utility model may be practiced or carried out in other embodiments that depart from the specific details, and the details of the present description may be modified or varied from the spirit and scope of the present utility model.

As described in detail in the embodiments of the present utility model, the cross-sectional view of the device structure is not partially enlarged to a general scale for convenience of explanation, and the schematic drawings are only examples, which should not limit the scope of the present utility model. In addition, the three-dimensional dimensions of length, width and depth should be included in actual fabrication.

For ease of description, spatially relative terms such as "under", "below", "beneath", "above", "upper" and the like may be used herein to describe one element or feature's relationship to another element or feature as illustrated in the figures. It will be understood that these spatially relative terms are intended to encompass other orientations of the device in use or operation in addition to the orientation depicted in the figures. Furthermore, when a layer is referred to as being "between" two layers, it can be the only layer between the two layers or one or more intervening layers may also be present.

In the context of the present utility model, a structure described as a first feature being "on" a second feature may include embodiments where the first and second features are formed in direct contact, as well as embodiments where additional features are formed between the first and second features, such that the first and second features may not be in direct contact.

It should be noted that, the illustrations provided in the present embodiment merely illustrate the basic concept of the present utility model by way of illustration, and only the components related to the present utility model are shown in the drawings rather than the number, shape and size of the components in actual implementation, and the form, number and proportion of each component in actual implementation may be arbitrarily changed, and the layout of the components may be more complex.

Referring to fig. 1-10, the micro liquid dispensing device provided in this embodiment mainly comprises a sample tube 1, a liquid separating mechanism 2, a sealing plug 3, a first control valve 4, a second control valve 5, a screw pushing and injecting mechanism 6 and a conical tube 7.

The upper end of the sample tube is provided with an opening, and the sealing plug 3 can be wholly or partially embedded into the opening, so that the opening is sealed, and the inner cavity of the sample tube is isolated from the external environment. By such a design, contamination of the sample by aerosols or the like in the external environment during liquid dispensing can be avoided. The sealing plug 3 may take the form of a rubber plug of various forms commonly known in the art, such as the one shown in fig. 5.

The liquid separating mechanism 2 comprises a liquid storage cavity 21, a first liquid flow channel 22 and a second liquid flow channel 28, wherein the liquid storage cavity 21 is communicated with the inner cavity of the sample tube and the conical tube 7 through the first liquid flow channel 22 and the second liquid flow channel 28 respectively. Wherein the diameters of the first and second fluid passages 22, 28 may be millimeter or micrometer, depending on the actual needs. For example, if a liquid of the order of micro liters is desired to be separated, the diameter of these flow channels is preferably of the order of microns.

The sample tube 1 and the liquid separating mechanism 2 can be connected with each other through a clamping mechanism or a threaded connection mechanism, etc. other connecting mechanisms which are common in the art can not be detached or can be detached. For example, in this embodiment, a first clamping mechanism and an infusion hole 11 are disposed on an outer wall of one side of the sample tube 1, a second clamping mechanism is disposed on an outer wall of one side of the liquid separation mechanism 2 opposite to the outer wall of one side of the sample tube 1, and when the first clamping mechanism and the second clamping mechanism are clamped and fixed, the infusion hole 11 is connected to the first flow channel 22, so that the inner cavity of the sample tube 1 is communicated with the liquid storage cavity 21. The first clamping mechanism comprises a first bump 12 and a first groove 13 which are arranged on the outer wall of one side of the sample tube at intervals, one end opening of the transfusion hole 11 is arranged on the bottom surface of the groove of the first groove 13, and the other end opening is exposed in the inner cavity of the sample tube 1, namely, the transfusion hole 11 penetrates through the outer wall of the sample tube 1. The second clamping mechanism comprises a second protruding block 23 and a second groove 24 which are arranged on the outer wall of one side of the liquid separating mechanism at intervals, one end opening of the first liquid flow channel 22 is a liquid inlet and is arranged on the top end face of the second protruding block 23, and the other end opening is a liquid outlet and is connected with the liquid storage cavity. The second bump 23 is configured to be engaged with the first groove 13 and form a sealing structure, and the second groove 24 is configured to be engaged with the first bump 12. By clamping the second protruding block 23 with the first groove 13 and clamping the second groove 24 with the first protruding block 12, the sample tube 1 and the liquid separating mechanism 2 can be conveniently and rapidly clamped and fixed, and meanwhile, the transfusion hole 11 can be communicated with the first liquid flow channel 22. Preferably, a plurality of micro-columns 14 protruding outwards along the radial direction can be further arranged on the outer wall of one side of the sample tube 1, a plurality of slots (not shown in the figure) recessed inwards along the radial direction can be arranged on the outer wall of one side of the liquid separation mechanism 2, the micro-columns can be tightly embedded into the corresponding micro-columns, and the combination of the micro-columns and the slots can enable the combination of the sample tube 1 and the liquid separation mechanism 2 to be firmer and more reliable. Wherein the first bump 12, the microcolumn 14, etc. may be integrally provided with the sample tube 1. The second projection 23 and the like may be provided integrally with the liquid separation mechanism 2.

With continued reference to fig. 7-8, the liquid separating mechanism in this embodiment is further provided with a first valve hole 25 and a second valve hole 26, where the first valve hole 25 is disposed to intersect the first liquid flow channel 22, and the second valve hole 26 is disposed to intersect the second liquid flow channel 28. Wherein the first fluid flow channel 22 may intersect the second fluid flow channel 28 perpendicularly, and accordingly, the axes of both the first valve bore 25 and the second valve bore 26 and the axes of both the first control valve and the second control valve may be perpendicular to each other.

The first control valve 4 is at least partially movably disposed in the first valve hole 25, and the communication and blocking of the first fluid passage 22 is achieved by driving the first control valve 4 to rotate about its own axis and/or to move along the axis of the first valve hole 25. The first control valve 4 may employ various types of valves known in the art, such as a rotary valve, a plunger valve, a shut-off valve, etc. From the standpoint of cost saving and ease of operation, the first control valve 4 may preferably be a spool valve with a handle as shown in fig. 1 and 2, which includes a valve body and a packing fitted over the valve body, the first flow passage 22 being blocked when the packing moves to a position crossing the first flow passage 22, and the first flow passage 22 being conducted when the packing moves away from the position crossing the first flow passage 22, so that the conduction and blocking of the first flow passage 22 can be controlled conveniently by driving the first control valve 4 to move along the axis of the first valve hole 25.

The second control valve 5 is at least partially movably disposed in the second valve hole 26 and is movable in an axial direction of the second valve hole, and the communication and blocking of the second fluid passage 28 is achieved by driving the second control valve 5 to move along the axial direction of the second valve hole 28. The second control valve 5 may be a plunger valve or the like as is conventional in the art. In some cases, the second control valve 5 may also be a common rotary valve, a shut-off valve, or the like.

Preferably, this embodiment may employ the second control valve 5 shown in fig. 6, which includes a valve body and two annular sealing sleeves 57 matched therewith, where the valve body may include a first portion and a second portion distributed along an axial direction thereof, where the first portion is configured to be placed into the second valve hole 26, and may include a first annular protruding portion 51, a second annular protruding portion 54, a third annular protruding portion 53, and an annular concave portion 52, where the first annular protruding portion, the annular concave portion, and the third annular protruding portion are sequentially disposed along an axis of the valve body, where the second annular protruding portion is disposed in the annular concave portion, and where the first annular protruding portion and the third annular protruding portion are each capable of being movably sealed and matched with the second valve hole, and where a diameter of the second annular protruding portion is smaller than a diameter of the first annular protruding portion. The two ends of the annular sealing sleeve 57 are open, and a plurality of dot-shaped grooves 58 are distributed on the inner wall. More preferably, the valve body further comprises a plurality of dot-like projections 55 discretely distributed in a lower portion of the annular recess 52, and a height of the dot-like projections in a radial direction of the valve body is smaller than a height of the first annular projections in the radial direction of the valve body. When two annular sealing sleeves 57 are sleeved at the annular concave lower part of the valve body, each point-shaped protruding part 55 is embedded into the corresponding point-shaped groove 58, so that the annular sealing sleeves are combined with the valve body more tightly, and the outer walls of the annular sealing sleeves 57 are basically flush with the outer walls of the first annular protruding part 51 and the third annular protruding part 53. By moving the second control valve 5 in the axial direction of the second control valve 5 and causing the second annular protrusion 54 to reach the position crossing the second flow passage 28, the second flow passage 28 is conducted, and when any one of the annular seal sleeves 57 is brought to the position crossing the second flow passage 28, the second flow passage 28 is blocked. Therefore, by moving the second control valve 5 in the axial direction, the conduction and blocking of the second flow channel 28 can be controlled, which is convenient and quick. The second portion may be considered the aft portion of the valve body and may include a handle structure disposed outside of the second valve bore 26 for operator manipulation.

The screw pushing and injecting mechanism 6 in this embodiment is movably matched with the liquid separating mechanism, and is used for driving the liquid in the liquid storage cavity to enter the conical tube 7 through the second liquid flow channel 28 in a screw pushing and injecting mode. Specifically, the liquid storage chamber 21 of the liquid separating mechanism 2 further has a connection port 27. The structure of the screw pushing and injecting mechanism is shown in fig. 9-10, and the screw pushing and injecting mechanism consists of a body 61 with an external thread structure at the head and a sealing ring 62 sleeved at the tail of the body 61, wherein the external thread structure is movably and hermetically matched with an internal thread structure at the upper part of the connecting port 27, and the tail of the screw pushing and injecting mechanism is slidably and hermetically matched with the inner wall at the middle lower part of the connecting port 27. When the screw pushing mechanism 6 is moved axially in the reservoir chamber 21 and presses the liquid in the reservoir chamber 21, the liquid can be made to enter the conical tube 7 through the second liquid flow passage 28. The use of the screw bolus mechanism 6 allows for a more accurate and controlled volume of liquid to be dispensed each time than a piston-type pushing mechanism.

The conical tube 7 in this embodiment is detachably connected to the dispensing mechanism, and the structure thereof can be seen in fig. 11-12. Or alternatively, the conical tube 7' shown in fig. 13-14, or other types of conical tubes as are conventional in the art. In some cases, it is possible to form a cone-shaped structure, similar in structure and function to the cone-shaped tube 7, integrally in the lower part of the liquid dividing structure, and also to provide a liquid flow channel in the cone-shaped structure.

The components or portions of the micro-fluid dispensing device of this embodiment may be made of plastic such as polyethylene, by processes known in the art such as injection molding, machining, and the like, and are not limited thereto.

The method for dispensing trace liquid by using the trace liquid dispensing device can be as follows: the liquid sample is introduced into the inner cavity of the sample tube 1 through the opening part of the sample tube (the sample tube can be pre-stored with a cracking reagent, a buffer solution and the like), and then the opening part is sealed by the sealing plug 3, and in the process, the first liquid flow channel 22 and the second liquid flow channel 28 are blocked by the first control valve 4 and the second control valve 5 respectively. Thereafter, the first control valve 4 is adjusted to make the first flow channel 22 conductive, so that the liquid sample in the sample tube 1 is sucked into the liquid storage chamber 21 under the negative pressure action in the liquid storage chamber 21 (the negative pressure action can be formed by previously evacuating the liquid storage chamber 21 or by moving the screw pushing mechanism 6 to form in the liquid storage chamber 21), and the second flow channel 28 is kept blocked during this process. Then, the first control valve 4 is regulated again to block the first flow channel 22, the second control valve 5 is regulated to conduct the second flow channel 28, and the screw pushing mechanism 6 is moved by a corresponding distance according to the volume of the liquid sample to be distributed, so that the liquid storage cavity 21 is pushed to enter the conical tube 7 through the second flow channel 28. The liquid separation process is simple to operate, good in controllability and high in accuracy, and can well meet the requirements of practical application.

The above embodiments are merely illustrative of the principles of the present utility model and its effectiveness, and are not intended to limit the utility model. Modifications and variations may be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the utility model. Accordingly, it is intended that all equivalent modifications and variations of the utility model be covered by the claims, which are within the ordinary skill of the art, be within the spirit and scope of the present disclosure.

Claims

1. A micro-fluid dispensing device, comprising: the device comprises a sample tube, a sealing plug, a liquid separation mechanism, a conical tube, a first control valve, a second control valve and a screw pushing and injecting mechanism;

2. The micro-fluid dispensing device of claim 1, wherein: the opening part is arranged at the upper end of the sample tube, and the sealing plug is at least partially embedded into the opening part, so that the opening part is sealed.

3. The micro-fluid dispensing device of claim 1, wherein: be equipped with first joint mechanism and transfusion hole on the outer wall of one side of sample cell, be equipped with second joint mechanism on the outer wall of one side of liquid dividing mechanism, work as first joint mechanism and second joint mechanism joint are fixed, the transfusion hole is connected with first liquid flow channel to communicate the inner chamber and the stock solution chamber of sample cell.

4. A micro-fluid dispensing device as claimed in claim 3, wherein: the first clamping mechanism comprises a first groove and a first bump which are arranged on the outer wall of one side of the sample tube at intervals, one end opening of the transfusion hole is arranged on the bottom surface of the groove of the first groove, and the other end opening is exposed in the inner cavity of the sample tube; the second clamping mechanism comprises a second groove and a second bump which are arranged on the outer wall of one side of the liquid separating mechanism at intervals, one end opening of the first liquid flow channel is arranged on the top end surface of the second bump, and the other end opening of the first liquid flow channel is connected with the liquid storage cavity; the second lug is used for being clamped with the first groove to form a sealing structure, and the second groove is used for being clamped with the first lug.

5. The micro-fluid dispensing device of claim 4, wherein: the first clamping mechanism and the sample tube are integrally arranged; and/or the second clamping mechanism and the liquid separating mechanism are integrally arranged; and/or, the first flow channel and the second flow channel are intersected with each other.

6. The micro-fluid dispensing device of claim 1, wherein: the liquid separation mechanism is also provided with a first valve hole, the first valve hole is crossed with the first liquid flow channel, the first control valve is at least partially movably arranged in the first valve hole, and the conduction and the blocking of the first liquid flow channel are realized by driving the first control valve to rotate around the axis of the first control valve and/or move along the axis of the first valve hole.

7. The micro-fluid dispensing device of claim 1, wherein: the liquid separation mechanism is also provided with a second valve hole, the second valve hole and the second liquid flow channel are arranged in a crossing way, the second control valve is at least partially movably arranged in the second valve hole and can axially move along the second valve hole, and the conduction and the blocking of the second liquid flow channel are realized by driving the second control valve to move along the axis of the second valve hole.

8. The micro-fluid dispensing device of claim 7, wherein: the second control valve comprises a valve body and two annular sealing sleeves, the valve body comprises a first annular protruding portion, a second annular protruding portion, a third annular protruding portion and an annular concave portion, the first annular protruding portion, the annular concave portion and the third annular protruding portion are sequentially arranged along the axis of the valve body, the second annular protruding portion is arranged in the annular concave portion, the diameter of the second annular protruding portion is smaller than that of the first annular protruding portion, the two annular sealing sleeves are sleeved at the annular concave portion and distributed on two sides of the second annular protruding portion, the outer wall of the annular sealing sleeve is flush with the first annular protruding portion and the third annular protruding portion, when the second annular protruding portion reaches the position crossing the second flow channel, the second flow channel is conducted, and when any annular sealing sleeve reaches the position crossing the second flow channel, the second flow channel is blocked.

9. The micro-fluid dispensing device of claim 8, wherein: the valve body further comprises a plurality of point-shaped protruding parts which are discretely distributed in the annular concave lower part, the height of the point-shaped protruding parts protruding along the radial direction of the valve body is smaller than that of the first annular protruding part protruding along the radial direction of the valve body, a plurality of point-shaped grooves are distributed on the inner wall of the annular sealing sleeve, and each point-shaped groove is matched with a corresponding point-shaped protruding part.

10. The micro-fluid dispensing device of claim 1, wherein: the axis of the first control valve is perpendicular to the axis of the second control valve; and/or the conical tube is detachably connected with the liquid separating mechanism.