CN220413372U - Disposable cell filtration collector and cell filtration collection device using same - Google Patents

Abstract

The utility model belongs to the technical field of physical separation of biological tissue blocks in medical technology, and particularly relates to a disposable cell filtration collector and a cell filtration collection device using the same, wherein the cell filtration collector comprises a filter body and an auxiliary support body; the filter body comprises a tube body, an inlet stripping structure, an outlet stripping structure and a vibrating ball group; the auxiliary support body is integrally formed on the outer wall of the pipe body, the auxiliary support body is provided with a clamping and positioning structure and a fool-proof structure, and the auxiliary support body is provided with a support plane for supporting the pipe body to be horizontally placed. The cell filtration collection device comprises a cell filtration collector, a clamping support frame and a closed cavity. The method is used for separating, filtering and collecting the cell tissues, is convenient for extracting and processing the fragmented adipose tissue micro-fragments of the biological tissue blocks, ensures that the fragmentation and filtering operations of adipose tissues are simpler and more convenient, and the operations are carried out in a relatively closed cavity environment which is sterilized in advance, so that the probability of microbial and bacterial pollution can be reduced to the greatest extent.

Description

Disposable cell filtration collector and cell filtration collection device using same

Technical Field

The utility model belongs to the technical field of physical separation of biological tissue blocks in medical technology, and particularly relates to a disposable cell filtration collector and a cell filtration collection device using the same.

Background

Cell differentiation is the process by which stability differences occur in morphology, structure and physiological function in multicellular organisms, resulting from proliferation of one or more cells. When stem cells divide, their daughter cell gene expression is regulated to produce populations of cells that proliferate into different populations. Adipose tissue is an important energy balance regulating organ in the human body, and is classified into white fat, brown fat and beige fat according to functions. White fat is used to store energy, while brown and beige fats increase energy loss and release heat mainly through mitochondrial uncoupling protein action. Adipose stem cells can be isolated from adipose tissue, and the adipose tissue also contains a large amount of pericytes, mesenchymal stem cells, hematopoietic stem cells, exosomes, various growth factors, and the like. The adipose tissue is fragmented to separate adipose tissue micro-fragments containing a plurality of effective products, and then the adipose tissue micro-fragments are subjected to further specific treatment and then are subjected to autologous transplantation, so that the repair treatment of autologous biological tissues can play good roles in regenerating cells of cell groups at transplantation positions, repairing defects, activating functional environments, improving the functional environments and the like.

In the prior art, the main method for acquiring the effective stem cells and other effective substances in adipose tissue is to cut the extracted adipose tissue manually or by other mechanical means by medical staff, filter the cut adipose tissue, and separate various components of adipose tissue fragments by rotary centrifugation to further acquire the effective adipose tissue micro-fragments. In the extraction process, a plurality of effective functional components are lost or damaged, the acquisition quality of the final fat micro-segment is greatly related to the earlier-stage fat tissue shearing operation, the extraction of the effective functional components can be influenced by the excessive large fat tissue blocks, and the survival rate of stem cells and other functional cells and the integrity of other effective functional components can be influenced by the excessive small fat tissue blocks. Moreover, this procedure is not only time-consuming and laborious, but it does not guarantee that the size of the pieces processed is substantially the same in the treatment of the preliminary fragmentation of adipose tissue, which also makes a considerable difference between the quality and the effective quantity of the final product obtained by the different personnel operations. At the same time, most of the operation procedures are performed manually and exposed to air in the whole operation flow, so that the problem of pollution of the final product by microorganisms and bacteria in the air is highlighted.

Therefore, based on the problems, the disposable processing device for separating, filtering and collecting the cell tissues is designed to facilitate the extraction and treatment of the fragmented adipose tissue micro-fragments of the biological tissue blocks, so that the fragmentation and filtering operations of the adipose tissues are simpler and more convenient, the probability of the tissues not being polluted can be ensured, and the adipose tissue micro-fragments have important practical significance.

Disclosure of Invention

The utility model aims to solve the problems in the prior art, and provides a disposable cell filtration collector for separating, filtering and collecting cells and a cell filtration collection device using the same, which are convenient for extracting and processing fragmented adipose tissue micro-fragments of a biological tissue block, and enable the fragmentation and filtration operation of adipose tissues to be simpler and more convenient.

The technical scheme adopted by the utility model for solving the problem is as follows:

a disposable cell filtration harvester comprising:

the filter body comprises a tube body, an inlet stripping structure arranged at the input end of the tube body, an outlet stripping structure arranged at the output end of the tube body, and a vibrating ball group which is contained in the tube body and is positioned between the inlet stripping structure and the outlet stripping structure;

the auxiliary support body is integrally formed on the outer wall of the pipe body, the auxiliary support body is provided with a clamping and positioning structure and a fool-proof structure, and the auxiliary support body is also provided with a support plane for supporting the pipe body to be horizontally placed.

Preferably, the inlet stripping structure comprises an upper end cover and an inlet stripping net, wherein the upper end cover is assembled at the input end of the pipe body, and the inlet stripping net is assembled between the upper end cover and the pipe body.

Further preferably, the outlet end stripping structure comprises a lower end cover and an outlet end stripping net, wherein the lower end cover is assembled at the output end of the pipe body, and the outlet end stripping net is assembled between the lower end cover and the pipe body.

Further preferably, after the tube body is assembled and sealed with the upper end cover and the lower end cover, a relatively sealed cylindrical cavity structure is formed.

Further preferably, the upper end cover and the lower end cover are both provided with reinforcing ribs on one side facing the pipe body.

It is further preferred that both the upper and lower end caps have three directional access ports, including, in addition to access ports to the interior of the filter body, an axial standard luer lock fitting and a radial fluid port.

Further preferably, the mesh openings of the entrance end stripping net and the exit end stripping net are uniform honeycomb shapes, and the mesh opening of the exit end stripping net is smaller than that of the entrance end stripping net.

Further preferably, the entry end peel web and the exit end peel web have a degree of rigidity and toughness.

Further preferably, the oscillating ball group comprises a plurality of metal oscillating balls.

Further preferably, the auxiliary support body comprises a vertical rib extending along the axial direction of the pipe body and a plurality of parallel transverse ribs which are arranged at equal intervals, the transverse ribs are mutually perpendicular to the vertical ribs, the vertical ribs are positioned on the central axis of the transverse ribs, and the side surfaces of the vertical ribs and the transverse ribs, which are far away from the pipe body, jointly form a support plane.

Further preferably, the clamping and positioning structure includes a positioning groove formed between the vertical rib and the lateral rib and clamping grooves formed at both sides of the lateral rib, and the fool-proof structure includes fool-proof clamping notches formed at edges of the lateral rib at the uppermost/lower ends.

The second utility model of the present utility model aims at: the utility model provides a cell filtration collection system, including foretell disposable cell filtration collector, still include centre gripping support frame and seal the cavity, disposable cell filtration collector is installed in seal the cavity by the vertical centre gripping of forward/reverse through the centre gripping support frame.

Preferably, the clamping support frame comprises a support backrest and two clamping arms symmetrically assembled on two sides of the support backrest and provided with opposite openings, and an elastic piece is arranged between the two clamping arms and the support backrest.

Further preferably, the front surface of the supporting backrest is provided with a positioning protrusion which is inserted in the positioning groove in an adapting way.

Further preferably, the front surface of the supporting backrest is provided with fool-proof clamping protrusions which are adaptively clamped at fool-proof clamping gaps.

Further preferably, the opening end of the clamping arm is provided with a clamping protrusion which is adapted to be clamped on the clamping groove.

Further preferably, the back of the supporting backrest is connected with the fixed supporting seat through a connecting piece, a pair of fixed arms are symmetrically arranged on the back of the fixed supporting seat, and the fixed arms are connected through a bolt and nut assembly.

The utility model has the advantages and positive effects that:

1. the utility model is a treatment device for separating, filtering and collecting the cell tissues, which is convenient for extracting and treating the fragmented adipose tissue micro-fragments of the biological tissue blocks, and ensures that the fragmentation and filtering operations of adipose tissues are simpler and more convenient.

2. In the utility model, the manual workload of medical staff in repeated operations of shearing and filtering tissue blocks is completely replaced by the cell filtering collector, thus the workload of staff in the original tissue micro-segment extraction process can be reduced to the greatest extent, and the operation period is also shortened greatly.

3. The operation of the utility model is carried out in a relatively closed cavity environment which is sterilized in advance, and the probability of microbial and bacterial pollution can be reduced to the greatest extent.

4. In the utility model, the auxiliary support body can play an auxiliary supporting role, so that the cell filtration collector can be stably and transversely placed and can be stably and vertically placed.

5. According to the utility model, when the cell filtration collector is required to vertically stand still, the cell filtration collector is fixed with the clamping support frame through the auxiliary support body, so that the cell filtration collector is vertically clamped and installed in the closed cavity in the forward direction or the reverse direction, and through the arrangement of the fool-proof clamping notch, the forward and reverse directions of the cell filtration collector can be rapidly and accurately identified, and the cell filtration collector can be prevented from being installed on the clamping support frame in the wrong reverse direction.

6. The size of the fragments of the fragmented tissue blocks finally obtained by the operation of the utility model and the separation quality can be ensured to a certain extent, and the substance components after separation and filtration can be directly obtained in the final step.

Drawings

The technical solution of the present utility model will be described in further detail below with reference to the accompanying drawings and examples, but it should be understood that these drawings are designed for the purpose of illustration only and thus are not limiting the scope of the present utility model. Moreover, unless specifically indicated otherwise, the drawings are intended to conceptually illustrate the structural configurations described herein and are not necessarily drawn to scale.

FIG. 1 is a schematic view showing the structure of a cell filtration collector, a holding support frame and a support rod in the assembled state in example 2;

FIG. 2 is a schematic diagram of the explosive structure of the cell filtration collector in example 1;

FIG. 3 is a front view of the cell filtration collector of example 1;

FIG. 4 is a schematic axial cross-section of the cell filtration collector of example 1;

FIG. 5 is a schematic diagram showing the assembly of the cell filtration collector of example 1 with its auxiliaries during the implementation;

FIG. 6 is a schematic view of an exploded structure of the cell filtration collector and the clamping frame in example 2;

FIG. 7 is an enlarged schematic view of the structure of the portion X in FIG. 6;

FIG. 8 is a schematic view of the structure of FIG. 6 in another angular state;

FIG. 9 is a schematic view showing a partial structure of a cell filtration collector and a holding frame in example 2;

FIG. 10 is a top view of the clamp support bracket;

fig. 11 is a front view of the clamp support bracket.

In the figure: 1. an upper end cap; 2. an in-end stripping net; 3. a tube body; 4. an outlet end stripping net; 5. a lower end cap; 6. a metal oscillating ball; 7. an auxiliary support body; 701. vertical ribs; 702. transverse ribs; 703. a support plane; 704. a positioning groove; 705. a clamping groove; 706. fool-proof clamping notch; 8. reinforcing ribs; 9. clamping the supporting frame; 901. a support backrest; 902. a clamping arm; 903. positioning the bulge; 904. fool-proof clamping protrusions; 905. clamping the protrusion; 10. a connecting piece; 11. fixing the supporting seat; 12. a fixed arm; 13. a bolt and nut assembly; 14. and (5) supporting the rod.

I, a process injector; II, collecting a syringe; III, a physiological saline bag and a liquid path hose thereof; IV, a waste collection bag and a liquid path hose thereof; v, feeding a liquid path clamp; VI, a liquid outlet clip.

Detailed Description

First, it should be noted that the following detailed description of the specific structure, characteristics, advantages, and the like of the present utility model will be given by way of example, however, all descriptions are merely illustrative, and should not be construed as limiting the present utility model in any way. Furthermore, any single feature described or implied in the embodiments mentioned herein, or any single feature shown or implied in the figures, may nevertheless be continued in any combination or pruning between these features (or equivalents thereof) to obtain still further embodiments of the utility model that may not be directly mentioned herein. In addition, for the sake of simplicity of the drawing, identical or similar features may be indicated at one point in the same drawing.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "configured," "connected," "secured," "screwed," and the like are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intermediaries, or in communication with each other or in interaction with each other, unless explicitly defined otherwise, the meaning of the terms described above in this application will be understood by those of ordinary skill in the art in view of the specific circumstances. The present utility model will be described in detail with reference to the accompanying drawings.

Example 1:

a disposable cell filtration harvester comprising: the filter body comprises a tube body 3, an inlet stripping structure arranged at the input end of the tube body 3, an outlet stripping structure arranged at the output end of the tube body 3 and a vibrating ball group which is contained in the tube body 3 and is positioned between the inlet stripping structure and the outlet stripping structure; the auxiliary support body 7 is integrally formed on the outer wall of the pipe body 3, the auxiliary support body 7 is provided with a clamping and positioning structure and a fool-proof structure, and the auxiliary support body 7 is also provided with a support plane for supporting the pipe body to be horizontally placed.

In this embodiment, as shown in fig. 1 to 11, the disposable cell filtration collector comprises a tube body 3, an inlet stripping structure installed at the input end of the tube body 3, an outlet stripping structure installed at the output end of the tube body 3, a vibrating ball group contained in the tube body 3 and an auxiliary support body 7 integrally formed on the outer wall of the tube body 3. The auxiliary support body 7 can play an auxiliary supporting role, not only can assist the stable transverse placement of the cell filtration collector, but also can assist the stable vertical placement of the cell filtration collector. The inlet stripping structure comprises an upper end cover 1 and an inlet stripping net 2, the outlet stripping structure comprises a lower end cover 5 and an outlet stripping net 4, and after the pipe body 3 is assembled and sealed with the upper end cover 1 and the lower end cover 5, a relatively sealed cylindrical cavity structure is formed. The inlet stripping net 2 is assembled on one side of the upper end cover of the pipe body 3, the outlet stripping net 4 is assembled on one side of the lower end cover of the pipe body 3, the meshes of the inlet stripping net 2 and the outlet stripping net 4 are uniform honeycomb, the mesh hole diameter of the outlet stripping net 4 is smaller than the mesh hole diameter of the inlet stripping net 2, and the whole tissue block is uniformly separated and cut; the upper end cover 1 and the lower end cover 5 are respectively assembled at two sides of the pipe body 3, and the metal oscillating ball 6 is arranged in the pipe body 3 and is used for further crashing and separating tissue blocks through stirring of the metal oscillating ball during oscillating operation.

The concrete work is as follows: through a process injector I; collecting a syringe II; physiological saline bag and liquid path hose III; a waste collection bag and a liquid path hose IV; a liquid feeding path clamp V; the auxiliary collection of the final required components is completed by the lower liquid path clamp VI. As shown in fig. 5, the axial interface a of the process injector i and the upper end cover 1 is movably connected through a luer connector, the axial interface B of the collection injector ii and the lower end cover 5 is movably connected through a luer connector, the physiological saline bag and the liquid path hose iii thereof are fixedly and hermetically connected with the radial interface C of the upper end cover 1, the waste collection bag and the liquid path hose iv thereof are fixedly and hermetically connected with the radial interface D of the lower end cover 5, the upper liquid path clamp v is positioned on the hose of the physiological saline bag and the liquid path hose iii thereof to control the opening and closing of the loop thereof, and the lower liquid path clamp vi is positioned on the hose of the waste collection bag and the liquid path hose iv thereof to control the opening and closing of the loop thereof.

In this embodiment, the processing device is required to process human adipose tissue, and the operation procedure of injecting the fat into the disposable cell filtration collector may be:

s1, opening an upper liquid path clamp V and a lower liquid path clamp VI, injecting normal saline into a closed cavity of a device main body through a normal saline bag and a liquid path hose III thereof, filling up, and then closing the upper liquid path clamp V;

s2, injecting the extracted adipose tissue into a closed cavity through a process injector I which is movably connected with an axial connector A through a luer connector, wherein in the process, an inlet stripping net 2 positioned at an input end can uniformly cut and separate the passed adipose tissue for the first time;

s3, ensuring that the upper liquid path clamp V and the lower liquid path clamp VI are in an open state, and fully shaking a cylindrical closed cavity formed by the pipe body 3, the upper end cover 1, the inlet end stripping net 2, the outlet end stripping net 4 and the lower end cover 5 up and down along the axial direction, wherein in the operation process, the metal oscillating ball 6 can continuously move in the cavity to strike the adipose tissue blocks in the cavity to further separate and crush adipose tissues;

s4, until the adipose tissue in the cavity is light yellow transparent liquid, namely, a target substance fat micro-segment is obtained, the 180-degree reverse input end of the disposable cell filtration collector is downward, and the disposable cell filtration collector can be kept in a vertical state and kept stand for a short time by arranging the auxiliary support body 7 on the tube body 3 on the clamping support frame, so that the fragmented adipose tissue is layered near the lower end cover 5 positioned at the upper part at the moment;

s5, opening the upper liquid passage clamp V, closing the lower liquid passage clamp VI, extracting a certain amount of liquid by the injector I in the using process, and then closing the upper liquid passage clamp V; and the liquid in the injector I is injected in the process of pushing, meanwhile, because of the relation of internal pressure, adipose tissue positioned at the upper layer can be jacked into the collecting injector II connected with the axial connector B of the lower end cover 5 through a luer connector, when the adipose tissue passes through the outlet stripping net 4 with the mesh size smaller than that of the inlet stripping net 2, the outlet stripping net 4 can integrally cut and separate the adipose tissue again, and thus the collection of fragmented adipose tissue micro-fragments is completed.

By the operation of the specific implementation technical scheme, the manual workload of medical staff in repeated operations of shearing and filtering tissue blocks is completely replaced by the technical scheme of the utility model, the workload of staff in the original tissue micro-segment extraction process can be reduced to the greatest extent, and meanwhile, the operation period is also shortened greatly. The size of the segment volume and the separation quality of the fragmented tissue blocks finally obtained through the operation of the specific implementation technical scheme designed by the utility model can be ensured to a certain extent, and the substance components after separation and filtration can be directly obtained in the final step of the technical scheme of the utility model.

It should be noted that: based on the above technical solution, the process injector i, the collecting injector ii, the physiological saline bag and the liquid path hose iii thereof, the waste collecting bag and the liquid path hose iv thereof, the upper liquid path clip v, and the lower liquid path clip vi are only used as functional auxiliary parts for assisting the patent of the present utility model to complete the specific implementation, and the specific connection mode refers to the assembly schematic diagram of the present utility model and the auxiliary parts thereof in the specific implementation process of the present utility model in fig. 5.

Still further, it may be considered in this embodiment that the upper end cover 1 is assembled at the input end of the pipe body 3, the inlet stripping net 2 is assembled between the upper end cover 1 and the pipe body 3, the side of the upper end cover 1 facing the pipe body 3 is provided with reinforcing ribs 8, the reinforcing ribs arranged at the inner side of the upper end cover 1 form a skeleton supporting surface for supporting the inlet stripping net 2 at the corresponding position, and are used for correspondingly supporting the inlet stripping net 2 to avoid the excessive bending effect function or damage to the product structure when separating and filtering tissue blocks and continuously impacting by the metal oscillating ball 6.

Still further, it may be considered in this embodiment that the lower end cover 5 is assembled at the output end of the tube body 3, the outlet end stripping net 4 is assembled between the lower end cover 5 and the tube body 3, the side of the lower end cover 5 facing the tube body 3 is provided with reinforcing ribs 8, the reinforcing ribs arranged on the inner side of the lower end cover 5 form a skeleton supporting surface for supporting the outlet end stripping net 4 at the corresponding position, so as to correspondingly support the outlet end stripping net 4 to avoid the excessive bending influence function or damage to the product structure when separating and filtering tissue blocks and continuously impacting by the metal oscillating ball 6.

Furthermore, in this embodiment, it may be considered that the sealed cavity formed by assembling and sealing the tube body 3 with the upper end cover 1 and the lower end cover 5 is cylindrical, the inner side walls of the upper end cover 1 and the lower end cover 5 are fixedly connected with the outer side walls of the two ends of the tube body 3 in a sealing manner, and one end of the tube body 3 assembled with the upper end cover 1 is an input end; the one end that body 3 and lower extreme cover 5 assembled is the output, by upper end cover 1, the entry strip net 2 and the up end of the airtight cavity that body 3 constitutes, the lower terminal surface of the airtight cavity that body 3 constitutes by lower extreme cover 5, exit strip net 4 can bear the inside five metal of body 3 and shake the continuous striking of ball 6 when the operation, through the setting of entry strip net and exit strip net, can carry out an integral and even separation cutting when the tissue piece passes through.

Furthermore, it is also contemplated in this embodiment that both the upper end cap 1 and the lower end cap 5 have three directional ports, including, in addition to the port a/B to the interior of the filter body, an axial standard luer lock fitting and a radial fluid port C/D.

Further, it is also contemplated in this embodiment that the mesh openings of the entrance stripping net 2 and the exit stripping net 4 are both uniform honeycomb, and the mesh opening of the exit stripping net 4 is smaller than the mesh opening of the entrance stripping net 2.

Furthermore, it is also contemplated in this embodiment that the entry end and exit end stripping webs should have a certain rigidity and toughness in order to ensure the separation effect on the tissue mass.

Still further, it may be considered in this embodiment that the oscillating ball group includes a plurality of metal oscillating balls 6, taking this embodiment as an example, the oscillating ball group includes five metal oscillating balls, and the metal oscillating balls are located inside the pipe body and located between the inlet stripping net and the outlet stripping net, and during operation, the oscillating balls will oscillate in the cavity of the pipe body.

Still further, it may be considered in this embodiment that the auxiliary supporting body 7 includes a vertical rib 701 extending along an axial direction of the tube body 3 and a plurality of parallel and equally spaced transverse ribs 702, the transverse ribs 702 are perpendicular to the vertical ribs 701, the vertical ribs 701 are located on a central axis of the transverse ribs 702, and the sides of the vertical ribs 701 and the transverse ribs 702 far away from the tube body 3 together form a supporting plane 703, when the cell filtration collector needs to be placed flat, the cell filtration collector can be effectively prevented from rolling by placing the supporting plane 703 on a table board.

Still further, it is also considered in the present embodiment that the holding and positioning structure includes a positioning groove 704 formed between the vertical rib 701 and the lateral rib 702 and holding grooves 705 formed at both sides of the lateral rib 702, and the fool-proof structure includes fool-proof catching notches 706 formed at edges of the lateral rib 702 located at the uppermost/lower ends, and the placement direction of the product is ensured by fool-proof catching.

Example 2:

the cell filtration collection system of embodiment 1, including disposable cell filtration collector still includes centre gripping support frame 9 and closed cavity, disposable cell filtration collector is installed in closed cavity by the vertical centre gripping of forward/reverse through centre gripping support frame 9. Through setting up the sealed cavity to install the bracing piece of vertical setting in the sealed cavity, fix centre gripping support frame 9 on the bracing piece, when the vertical cell filtration collector of standing of needs, the cell filtration collector is fixed with centre gripping support frame 9 through auxiliary stay body 7, makes the cell filtration collector by the vertical centre gripping of forward/reverse install in the sealed cavity, because the concrete implementation operation of whole technical scheme all is going on in the relatively sealed cavity environment of sterilizing in advance, can furthest reduce microorganism and bacterial contamination's probability.

Still further, it may be considered that in this embodiment, the holding support 9 includes a support backrest 901 and two holding arms 902 symmetrically assembled on two sides of the support backrest 901 and having opposite openings, an elastic member is installed between the two holding arms 902 and the support backrest 901, a positioning protrusion 903 adapted to be inserted into the positioning groove 704 and a foolproof clamping protrusion 904 adapted to be clamped at the foolproof clamping notch 706 are provided on the front surface of the support backrest 901, and a holding protrusion 905 adapted to be clamped on the holding groove 705 is provided on the open end of the holding arm 902. When the cell filtration collector needs to vertically stand, the auxiliary support body 7 is aligned to the clamping support frame 9 for insertion, the positioning protrusion 903 is just inserted in the positioning groove 704, the fool-proof clamping protrusion 904 is just inserted in the fool-proof clamping notch 706, a fool-proof positioning effect is achieved, the product placement direction is guaranteed, meanwhile, the clamping protrusion 905 of the clamping arm 902 is just clamped on the clamping groove 705, the adaptation installation of the auxiliary support body 7 and the clamping support frame 9 is realized, the positive and negative directions of the cell filtration collector can be rapidly and accurately identified, and the cell filtration collector can be prevented from being installed on the clamping support frame 9 in the wrong reverse direction.

Furthermore, it is also contemplated in this embodiment that the back of the support backrest 901 is connected to the fixed support seat 11 through the connecting member 10, the connecting member 10 may be, but not limited to, a commercially available rotating shaft structure with a locking function, the back of the fixed support seat 11 is symmetrically provided with a pair of fixing arms 12, the fixing arms 12 are connected by a bolt-nut assembly 13, and the fixing arms can be fixed on the support rod 14 by rotating the bolt-nut assembly 13.

The technical scheme of the embodiment of the utility model solves the problem that the manual workload of medical staff in repeated operations of shearing and filtering tissue blocks in the process of fragmenting adipose tissues in the prior art is completely replaced by the technical scheme of the utility model, reduces the manual workload and greatly shortens the working period, and because the specific implementation operation of the whole technical scheme is carried out in a relatively closed cavity environment which is sterilized in advance, the probability of microbial and bacterial pollution is reduced to the greatest extent.

The foregoing examples illustrate the utility model in detail, but are merely preferred embodiments of the utility model and are not to be construed as limiting the scope of the utility model. All equivalent changes and modifications within the scope of the present utility model are intended to be covered by the present utility model.

Claims (10)

1. A disposable cell filtration collector, characterized in that: comprising the following steps:

the filter body comprises a tube body (3), an inlet stripping structure arranged at the input end of the tube body (3), an outlet stripping structure arranged at the output end of the tube body (3) and a vibrating ball group which is arranged inside the tube body (3) and is positioned between the inlet stripping structure and the outlet stripping structure;

the auxiliary support body (7) is integrally formed on the outer wall of the pipe body (3), the auxiliary support body (7) is provided with a clamping and positioning structure and a fool-proof structure, and the auxiliary support body (7) is also provided with a support plane for supporting the pipe body (3) to be horizontally placed.

2. A disposable cell filtration harvester according to claim 1, wherein: the inlet stripping structure comprises an upper end cover (1) and an inlet stripping net (2), wherein the upper end cover (1) is assembled at the input end of the pipe body (3), and the inlet stripping net (2) is assembled between the upper end cover (1) and the pipe body (3).

3. A disposable cell filtration harvester according to claim 2, wherein: the outlet stripping structure comprises a lower end cover (5) and an outlet stripping net (4), wherein the lower end cover (5) is assembled at the output end of the pipe body (3), and the outlet stripping net (4) is assembled between the lower end cover (5) and the pipe body (3).

4. A disposable cell filtration harvester according to claim 3, wherein: the upper end cover (1) and the lower end cover (5) are provided with three channel ports, and the filter comprises an axial standard luer lock connector and a radial liquid channel connector besides the channel port leading to the inside of the filter body.

5. A disposable cell filtration harvester according to claim 3, wherein: the mesh openings of the inlet end stripping net (2) and the outlet end stripping net (4) are uniform honeycomb, and the mesh opening of the outlet end stripping net (4) is smaller than the mesh opening of the inlet end stripping net (2).

6. A disposable cell filtration harvester according to claim 1, wherein: the auxiliary support body (7) comprises a vertical rib (701) extending along the axial direction of the pipe body (3) and a plurality of parallel equally-spaced transverse ribs (702), the transverse ribs (702) are perpendicular to the vertical rib (701), the vertical rib (701) is located on the central axis of the transverse rib (702), and the side surfaces, away from the pipe body (3), of the vertical rib (701) and the transverse rib (702) jointly form a support plane (703).

7. The disposable cell filtration harvester of claim 6, wherein: the clamping and positioning structure comprises positioning grooves (704) formed between the vertical ribs (701) and the transverse ribs (702) and clamping grooves (705) formed on two sides of the transverse ribs (702);

the fool-proof structure includes fool-proof detent notches (706) formed at edges of the transverse ribs (702) at the uppermost/lower ends.

8. A cell filtration collection device, characterized in that: comprising the disposable cell filtration collector according to any one of claims 1-7, further comprising a clamping support (9) and a closed cavity, wherein the disposable cell filtration collector is mounted in the closed cavity by being clamped vertically forward/vertically backward by the clamping support (9).

9. The cell filtration and collection device of claim 8 wherein: the clamping support frame (9) comprises:

a support backrest (901) with clamping arms (902) with opposite openings symmetrically arranged on two sides;

the positioning protrusions (903) are arranged on the front surface of the support backrest (901) and are correspondingly inserted in the positioning grooves (704) in a one-to-one fit manner;

the fool-proof clamping position protrusion (904) is arranged on the front surface of the supporting backrest (901) and is adaptively clamped at the fool-proof clamping position notch (706);

and a clamping protrusion (905) arranged at the opening end of the clamping arm (902) and adapted to be clamped in the clamping groove (705).

10. The cell filtration and collection device of claim 9, wherein: the back of the support backrest (901) is connected with a fixed support seat (11) through a connecting piece (10), a pair of fixed arms (12) are symmetrically arranged on the back of the fixed support seat (11), and the fixed arms (12) are connected through a bolt and nut assembly (13).