CN217338517U - Broad Spectrum Fluorescence Endoscopy Device - Google Patents

Abstract

The utility model discloses a wide-spectrum fluorescence endoscope device. The broad spectrum fluorescence endoscope apparatus includes: the device comprises a shell capable of being held and a flexible detection tube, wherein a first end of the detection tube is connected with the shell, a second end of the detection tube is a detection end capable of being placed in a region to be detected, and the second end of the detection tube is provided with more than two imaging objective lenses; the infrared light source, the visible light source, the image detection mechanism and the control mechanism are arranged in the shell, the infrared light source and the visible light source are respectively connected with at least one imaging objective lens through optical fiber cables, and the control mechanism is respectively connected with the image detection mechanism, the display mechanism, the infrared light source and the visible light source. The embodiment of the utility model provides a wide spectrum fluorescence endoscope device can realize higher space-time resolution.

Description

Broad Spectrum Fluorescence Endoscopy Device

technical field

The utility model relates to an endoscope device, in particular to a broad-spectrum fluorescence endoscope device, which belongs to the technical field of detection equipment.

Background technique

Medical endoscopes have been widely used in clinical testing and surgery, integrating optics, imaging, ergonomics and other disciplines, providing a reliable image basis for clinical diagnosis that is difficult to provide in vitro diagnosis, and for the digestive tract, It provides solutions for the diagnosis and treatment of various diseases such as vascular system, ENT, and celiac system diseases.

After a hundred years of development, in addition to the continuous improvement of the imaging resolution of endoscopes, many brands such as Japan's Olympus and Germany's Xion have proposed many advanced endoscope design solutions. For example, Olympus's two-color narrow-band endoscopes limit light of different wavelengths, leaving only red, green, and blue narrow-band light waves. The use of narrow-band light waves to penetrate the gastrointestinal mucosa at different depths enables the penetration of blood vessels of different depths. Xion's 3D imaging hard mirror in Germany realizes real-time 3D image imaging through dual optical path design, which improves the stereoscopic effect of endoscopic images and is beneficial for clinicians to observe the depth of tissues in endoscopic images.

However, the current endoscopic optical imaging wavelengths are basically based on the visible light region (400-650nm), and a very small part is based on traditional infrared (650-900nm). It is also affected by the absorption and scattering of photons, and is also seriously interfered by tissue autofluorescence, so it is difficult to achieve high penetration depth and high spatial resolution imaging of tissue. And short-wave infrared (900-2500nm) fluorescence imaging has lower tissue scattering and absorption, higher penetration depth, so the short-wave infrared endoscope optical imaging system has higher spatiotemporal resolution and detection depth, with better and wider application prospects.

Utility model content

The main purpose of the present invention is to provide a broad-spectrum fluorescence endoscope device to overcome the deficiencies in the prior art.

In order to realize the purpose of the aforementioned utility model, the technical scheme adopted by the present utility model includes:

The embodiment of the present utility model provides a broad-spectrum fluorescence endoscope device, including:

A shell that can be held and a flexible detection tube, the first end of the detection tube is connected to the outer shell, the second end is a detection end that can be placed in the area to be detected, and the second end of the detection tube is provided with Two or more imaging objectives;

Infrared light source, visible light source, image detection mechanism, control mechanism and display mechanism, the infrared light source, visible light source, image detection mechanism and control mechanism are arranged in the casing, and the infrared light source and visible light source are respectively connected with the optical fiber cable. at least one imaging objective lens is connected, and the control mechanism is respectively connected with the image detection mechanism, the display mechanism, the infrared light source and the visible light source;

The image detection mechanism can correspondingly convert the short-wave infrared fluorescence formed by the area to be detected under the irradiation of infrared excitation light and the visible light reflected by the area to be detected into a short-wave infrared fluorescence image signal and a visible light image signal; The visible light image signal and the short-wave infrared fluorescent image signal are displayed in a way visible to the human eye; the control mechanism is used for regulating and controlling the infrared light source and the visible light source.

Compared with the prior art, the advantages of the present utility model include: a broad-spectrum fluorescence endoscope device provided by the embodiment of the present utility model is simple in structure and easy to operate; An endoscope device, using an infrared light source that can provide infrared excitation light and a visible light source that can provide visible light as light sources, can achieve higher spatial and temporal resolution; The device adopts a flexible detection tube with a retractable corrugated tube structure, so that the specific operation can be more flexible, and the detection depth is further improved.

Description of drawings

1 is a schematic structural diagram of a broad-spectrum fluorescence endoscope device provided in a typical implementation case of the present utility model;

2 is a schematic structural diagram of the cooperation principle of a light source, an optical fiber cable and a controller in a broad-spectrum fluorescence endoscope device provided in a typical implementation case of the present invention;

FIG. 3 is a schematic flowchart of imaging with a broad-spectrum fluorescence endoscope device provided in a typical implementation case of the present invention.

Detailed ways

In view of the deficiencies in the prior art, the inventor of the present application has been able to propose the technical solution of the present invention after long-term research and extensive practice. The technical solution, its implementation process and principle will be further explained as follows.

The embodiment of the present invention provides a broad-spectrum fluorescence endoscope device, wherein the broad-spectrum fluorescence refers to the wavelength of 350-2500nm, preferably 350-1700nm. The maximum outer diameter of the detection tube is 1.2-15mm) into the cavity to be detected, so that the detected part marked by the fluorescent probe can achieve fluorescence excitation in the 350-2500nm band, and the excited 350-2500nm (preferably Fluorescence in the 350-1700 nm) band was imaged and presented as an image.

An endoscope is a device used by doctors to observe a patient's body without performing exploratory surgery. Generally, an endoscope is an imaging device with an insertion tube that is inserted into the patient's body through a small incision. The imaging device extends from the tip of the insertion tube ( The "distal end") provides a view, and the view is displayed on, for example, a doctor's monitor, the distal end may be opposite the hand-held portion ("proximal end") of the endoscope, and the imaging system may provide the viewer with a view of the region of interest view.

Indocyanine green (ICG) is a dye that binds to proteins in plasma. When excited with light around 808nm, ICG emits fluorescence with a wavelength range of 810nm-1400nm. The ICG can be injected into the bloodstream, and during surgery, the ICG can be imaged fluorescence to show blood perfusion and vasculature. In endoscopic surgery, the surgeon inserts an endoscope (with a camera and illumination source at the distal end of the endoscope) to image the surgical area of interest in real time. The broad-spectrum fluorescence endoscope device provided by the embodiment of the present invention can help solve the problem of obtaining a high-penetration depth and high-resolution short-wave infrared fluorescence image to show the spatial distribution of ICG while obtaining a regular visible reflection image in real time. question. ICG near-infrared region II fluorescence images can provide contrasting information that surgeons can use to better distinguish differences between various body structures. ICG can also be replaced by other clinically used fluorescent probes with near-infrared II region fluorescence.

In the following description, embodiments of the present invention are set forth in numerous specific details in order to provide a thorough understanding of the embodiments. One skilled in the relevant art will recognize, however, that the techniques described herein may be practiced without one or more of the specific details or with other methods, components, materials, etc. In other instances, well-known structures, materials, or operations have not been shown or described in detail to avoid obscuring certain aspects.

Throughout this specification, reference to "an embodiment" means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. Thus, appearances of the phrases "in one embodiment" or "in an embodiment" in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures or characteristics may be combined in any suitable manner in one or more embodiments.

The embodiment of the present utility model provides a broad-spectrum fluorescence endoscope device, including:

A shell that can be held and a flexible detection tube, the first end of the detection tube is connected to the outer shell, the second end is a detection end that can be placed in the area to be detected, and the second end of the detection tube is provided with Two or more imaging objectives;

Infrared light source, visible light source, image detection mechanism, control mechanism and display mechanism, the infrared light source, visible light source, image detection mechanism and control mechanism are arranged in the casing, and the infrared light source and visible light source are respectively connected with the optical fiber cable. at least one imaging objective lens is connected, and the control mechanism is respectively connected with the image detection mechanism, the display mechanism, the infrared light source and the visible light source;

The image detection mechanism can correspondingly convert the short-wave infrared fluorescence formed by the area to be detected under the irradiation of infrared excitation light and the visible light reflected by the area to be detected into a short-wave infrared fluorescence image signal and a visible light image signal; The visible light image signal and the short-wave infrared fluorescent image signal are displayed in a way visible to the human eye; the control mechanism is used for regulating and controlling the infrared light source and the visible light source.

In a specific embodiment, the visible light source and the infrared light source are independently connected to the control mechanism, and can be independently controlled.

In a specific embodiment, the optical fiber cable includes a light guide and an image transmission beam arranged in parallel in the detection tube, and the light guide and the image transmission beam can transmit optical signals in a wavelength range of 350-2500 nm.

In a specific embodiment, the imaging objective lens includes a plurality of microlenses arranged in sequence along the light transmission direction, wherein the imaging objective lens has a diameter of 0.4-10 mm.

In a specific embodiment, the first end of the detection tube has an internal thread structure, the housing has an external thread structure matching the internal thread structure, and the first end of the detection tube passes through the housing. threaded connection.

In a specific embodiment, the portion of the detection tube close to the first end has a corrugated tube structure that can be stretched and restored along its own length direction under the action of an external force.

In a specific embodiment, the second end of the detection pipe is provided with a detection head, and the detection head is connected with the detection pipe by means of screw connection and can be disassembled, wherein the detection head is provided with a plurality of There are two cylindrical accommodating cavities arranged in parallel, and each imaging objective lens is correspondingly embedded in a accommodating cavity.

In a specific embodiment, the image detection mechanism includes a camera, and the camera is a broad-spectrum sensing camera capable of simultaneously detecting visible light and short-wave infrared fluorescence, or the image detection mechanism includes a visible light image camera for detecting visible light and SWIR imaging camera for detecting SWIR fluorescence.

In a specific embodiment, the camera includes a detector, an imaging optical device and a filtering mechanism arranged at the receiving end of the detector, the filtering mechanism is at least used to filter out the infrared excitation light, and the imaging optical device is at least used to collect the The reflected visible and short-wave infrared fluorescence is reflected, and the collected reflected visible and short-wave infrared fluorescence is focused on a detector to form an optical image.

In a specific embodiment, the display mechanism includes a display for displaying a visible light image and a short wave infrared fluorescence image.

The technical solution, its implementation process and principle will be further explained below in conjunction with specific implementation cases and accompanying drawings. Unless otherwise specified, the controllers, lasers, displays, optical fibers used in the embodiments of the present invention Cables, optical lenses, cameras, and the like can all be known to those skilled in the art, and can be obtained commercially, and their specific structures and models are not limited here.

The embodiment of the present invention provides a broad-spectrum fluorescence endoscope device, the distal end of the broad-spectrum fluorescence endoscope device (the end is inserted into the surgical area) has two discrete laser sources and a 350-2500nm wavelength band A slender tube imaging device for fluorescence imaging (including a flexible detector tube and an imaging objective lens), and having at least one detector at the proximal end, the detectors include at least one 900-2500nm photosensitive detector (preferably a 900-1700nm detector) ); the light of 350-2500nm can be transmitted from the discrete laser source at the proximal end to the distal end (the transmission wavelength is preferably 350-1700nm) through the optical fiber cable.

The embodiments of the present utility model provide a broad-spectrum fluorescence endoscope device for processing data output by a detector and sending the data to a computer monitor, display software, laser, imaging lens, image detector, etc. All can be obtained from the market, and no special limitation or description is made here. It should be noted that the embodiments of the present utility model are intended to explain the structure and composition of the broad-spectrum fluorescence endoscope device, and its imaging principle and imaging. The process is basically the same as the existing endoscope device known to those skilled in the art, wherein the broad-spectrum fluorescence endoscope device provided by the embodiment of the present invention can be used for the purpose of diagnosis and treatment or non-diagnosis.

Example 1

Referring to FIG. 1 , a broad-spectrum fluorescence endoscope device includes a main body 10 that can be held, a flexible detection tube 17 , an optical fiber cable 11 , a visible light source 12 , an infrared light source 13 , an image detector 14 , and a controller 15 and a computer system 16, the main body 10 includes a hard case, the visible light source 12, the infrared light source 13, the image detector 14, and the controller 15 are packaged inside the hard case, and the optical fiber cable 11 is provided in the In the flexible detection tube 17, one end of the optical fiber cable 11 is connected to the visible light source 12 and the infrared light source 13, and the other end is connected to the imaging objective lens located in the detection tube 17. The controller 15 is respectively It is connected with the image detector 14 , the display, the computer system 16 , the visible light source 12 and the infrared light source 13 .

In this embodiment, the image detector 14 can respectively convert the short-wave infrared fluorescence formed by the area to be detected under the irradiation of infrared excitation light and the visible light reflected by the area to be detected into short-wave infrared fluorescence image signals and visible light image signals respectively; The controller 14 is used for regulating and controlling the infrared light source and the visible light source.

In this embodiment, the broad-spectrum fluorescence endoscope device includes a proximal end (hand-held) and a distal end (the end of the fiber optic cable 11 opposite to the proximal end), and the visible light source 12 and the infrared light source 13 are optically coupled to The proximal end of the optical fiber cable 11 is used to emit the light provided by the visible light source 12 and the infrared light source 13 into the optical fiber cable 11 and output from the far end; wherein, the optical fiber cable 11 is configured as a dual optical fiber and can simultaneously Both visible light and infrared excitation light are transmitted, and the wavelength of the infrared excitation light is outside the wavelength spectrum of visible light.

In this embodiment, the infrared light source 13 and the visible light source 12 can be an infrared laser and a visible light laser with a wavelength of about 808 nm, respectively, and the infrared light source 13 can also be replaced with other wavelength lasers, such as: 750 nm, 760 nm, 780 nm, 980nm, 1064nm, 1200nm, 1250nm, 1530nm and other wavelength lasers. The filter blocks almost all excitation light at wavelengths around 808nm, but lets other wavelengths through. Excitation light with a wavelength of about 808 nm and visible wavelength excitation light work simultaneously. The excitation light with a wavelength of about 808nm can make the ICG dye in the surgical area of interest fluoresce in the short-wave infrared region, and the visible light is reflected by the organs in the surgical area (ie, the area to be detected, the same below); the visible light is imaged by a visible light detector , SWIR fluorescence is imaged by a SWIR fluorescence detector, and the two imaging images can be separated or superimposed by a software algorithm. It is worth noting that visible light and SWIR fluorescence can be detected by separate detectors or by a broad spectrum For camera detection, the wide-spectrum camera’s sensitive range includes visible light and short-wave infrared light. If a wide-spectrum camera is used, the picture taken is the superposition of visible light and short-wave infrared light, and the two kinds of light can be decomposed by software algorithms. It should be noted that the software algorithm and the like can be obtained commercially.

It should be noted that different wavelengths of fluorescent probes and excitation light wavelengths can be used. In addition, more detectors of the same type can be used in the broad-spectrum fluorescence endoscope device for stereo imaging.

In this embodiment, the image detector 14 is coupled to the optical fiber cable 11, and can receive the visible light reflected from the area to be detected and the short-wave infrared fluorescence that is blocked by the filter to reach the image detector 14 from the infrared excitation light. Most of the reflected visible and short wave infrared fluorescence is passed to the image detector 14 .

Please refer to FIG. 2. FIG. 2 shows the structure of the light source in the embodiment of the present invention. The light source includes a visible light source 12 and an infrared light source 13. The visible light source 12 may include one or more visible light lasers. Light source 13 may include one or more infrared lasers from which visible light is emitted, and infrared excitation light emitted from one or more infrared lasers, the infrared excitation light having a wavelength longer than the wavelength spectrum of visible light, visible light lasers and The infrared laser may be a single laser diode capable of emitting light at multiple wavelengths or may be multiple independent laser diodes, each laser diode emitting light at a different wavelength.

In this embodiment, as shown in FIG. 2 , the light source can be optically coupled to the fiber optic cable 11 to guide visible light and infrared excitation light to the proximal end of the fiber optic cable 11 . Thus, the light is transmitted into the fiber optic cable 11 and the light is totally internally reflected within the fiber optic cable 11 until it reaches the far end from which it was emitted.

In this embodiment, the controller 15 is coupled to the visible light source 12 and the infrared light source 13 to adjust the outputs of the visible light source 12 and the infrared light source 13, wherein the controller 15 may be a part of the processor system, or, The controller 15 can be an independent controller for controlling the output of the visible light source 12 and the infrared light source 13; the controller 15 can independently control the intensity of each laser source to balance the amount of infrared excitation light and visible light emitted In one embodiment, the visible light source 12 and the infrared light source 13 may have any number of light sources (including lasers and/or light emitting diodes).

In this embodiment, the fiber optic cable 11 may include a cladding to facilitate total internal reflection (eg, the cladding may include a reflective metal, or a material having a lower index of refraction than the body of the fiber optic cable 11 ) or contain multiple fibers.

In this embodiment, the optical fiber cable 11 includes a light guide and an image transmission beam arranged in parallel in the detection tube, and the light guide and the image transmission beam can transmit optical signals in the 350-2500 nm band.

In this embodiment, the first end of the detection tube has an internal thread structure, the housing has an external thread structure matching the internal thread structure, and the first end of the detection tube and the housing are threaded The part of the detection tube close to the first end has a bellows structure that can be stretched and restored along its own length direction under the action of external force. When in use, the detection tube can be stretched to facilitate the The length of the detection tube can be extended, so as to improve the detection depth and detection range without increasing the overall volume of the broad-spectrum fluorescence endoscope device, so that the manipulation of the detection tube is more flexible and changeable.

It should be noted that the bellows structure is a part of the detection pipe body, and the bellows structure may be provided with one segment or multiple segments arranged at intervals.

In this embodiment, the second end of the detection pipe is provided with a detection head, and the detection head is connected with the detection pipe by means of screw connection and can be disassembled, wherein the detection head is provided with a plurality of The cylindrical accommodating cavities are arranged in parallel, and an imaging objective lens is arranged in each accommodating cavity, and the imaging objective lens is coupled with the optical fiber cable.

In this embodiment, the imaging objective lens includes a plurality of microlenses arranged in sequence along the light transmission direction, wherein the imaging objective lens has a diameter of 0.4-10 mm.

In this embodiment, the wavelength of the short-wave infrared fluorescence is 900-2500 nm, and the infrared excitation light can be any light with lower energy than the short-wave infrared fluorescence. It is worth noting that although in the depicted embodiment, the infrared excitation light and Short-wave infrared fluorescence is relatively monochromatic, but in other embodiments, the emission profiles of these light sources may be broader, such that they include multiple wavelengths of light (and may even include multiple emission peaks).

In this embodiment, the reflected visible light and short-wave infrared fluorescence form image data in the image detector 14, and the image data can be separated into visible image data and short-wave infrared fluorescence image data in real time by the processing system. The data is substantially consistent with reflected visible light received by image detector 14 , and the short-wave infrared fluorescence image data is substantially consistent with short-wave infrared fluorescence received by image detector 14 .

In this embodiment, if a broad-spectrum camera is used, the combined image data can be separated into visible image data and short-wave infrared fluorescence image data; and if a combination of a visible light camera and a short-wave infrared camera is used, the visible image data can be separated by a software algorithm. Fusion and overlay with short-wave infrared fluorescence image data.

It should be noted that those of ordinary skill in the art will understand that the depicted method and all parts of the process may take place in a processor/controller coupled to or included in the endoscopic device. Additionally, the endoscope may communicate with a local or remote processor via wireless or wired communication. In some embodiments, the processor/controller may be a distributed system (eg, in embodiments where large amounts of data need to be processed, eg, high-definition video). It should be understood that the depicted embodiment illustrates the case where the infrared excitation light is around 808 nm and the short-wave infrared fluorescence is 900-2500 nm, but in other embodiments, other wavelengths of infrared excitation light sources may be used.

FIG. 3 shows a method for performing medical imaging with a broad-spectrum fluorescence endoscopic device according to an embodiment of the present invention, and the order in which some or all of the methods shown in FIG. 3 appear should not be regarded as limiting . Rather, one of ordinary skill in the art having the benefit of the present embodiments will appreciate that some of the methods may be performed in various orders not shown or even in parallel.

A method of medical imaging with a broad spectrum fluorescence endoscopic device may include:

1) Simultaneous emission of visible light and infrared excitation light from the distal end of the fiber optic cable of the endoscope, in one embodiment, the excitation light has a wavelength outside the wavelength spectrum of visible light (eg, the excitation light has a longer wavelength than visible light; );

2) Using the image detector to receive the reflected visible light, in one embodiment, the infrared excitation light is blocked by the filter and not absorbed by the image detector. In some embodiments it may be a notch filter, or any other wavelength selective filtering;

3) Using an image detector to receive short-wave infrared fluorescence emitted from a plurality of dye molecules, and the short-wave infrared fluorescence is emitted in response to absorption of infrared excitation light by the plurality of dye molecules. Short-wave infrared fluorescence can have longer wavelengths than visible light or excitation light. The image detector receives both reflected visible light and shortwave infrared fluorescence. The reflected visible light and short-wave infrared fluorescence simultaneously form combined image data in the image detector;

4) separating the combined image data into visible image data; the visible image data is commensurate with the reflected visible light received by the image detector;

5) Separate the combined image data into short-wave infrared fluorescence image data; the short-wave infrared fluorescence image data is commensurate with the short-wave infrared fluorescence light received by the image detector. In one embodiment, if a broad-spectrum camera is used, the combined image data is separated into Visible image data and SWIR fluorescence image data. In one embodiment, if a combination of a visible light camera and a short-wave infrared camera is used, the visible image data and the short-wave infrared fluorescence image data can be fused and superimposed through a software algorithm.

In embodiments, the visible image data and the short wave infrared fluorescence image data may be utilized to form segmented images or overlay images, which allow the physician to clearly identify different areas of the body during surgery.

The broad-spectrum fluorescence endoscope device provided by the embodiment of the present invention has a simple structure and simple operation; the broad-spectrum fluorescent endoscope device provided by the embodiment of the present invention adopts an infrared light source that can provide infrared excitation light. and a visible light source that can provide visible light as a light source, which can achieve higher temporal and spatial resolution; and, a broad-spectrum fluorescence endoscope device provided by the embodiment of the present invention adopts a flexible detection tube with retractable corrugations The tube structure makes it more flexible in specific operations and further improves the depth of detection.

The above description of illustrated embodiments of the invention, including what is described in the Abstract, is not intended to be exhaustive or to limit the invention to the precise form disclosed. While specific embodiments of, and examples for, the invention are described herein for illustrative purposes, various modifications are possible within the scope of the invention, as those skilled in the relevant art will recognize.

It should be understood that the above-mentioned embodiments are only to illustrate the technical concept and characteristics of the present invention, and its purpose is to enable those who are familiar with the technology to understand the content of the present invention and implement accordingly, and cannot limit the protection of the present invention. scope. All equivalent changes or modifications made according to the spirit of the present invention shall be included within the protection scope of the present invention.

Claims (10)

1. A broad spectrum fluorescence endoscopic device, comprising:

the device comprises a shell capable of being held and a flexible detection tube, wherein a first end of the detection tube is connected with the shell, a second end of the detection tube is a detection end capable of being placed in a region to be detected, and the second end of the detection tube is provided with more than two imaging objective lenses;

the infrared light source, the visible light source, the image detection mechanism, the control mechanism and the display mechanism are arranged in the shell, the infrared light source and the visible light source are respectively connected with at least one imaging objective lens through optical fiber cables, and the control mechanism is respectively connected with the image detection mechanism, the display mechanism, the infrared light source and the visible light source;

the image detection mechanism can respectively and correspondingly convert short wave infrared fluorescence formed by the to-be-detected region under the irradiation of the infrared exciting light and visible light reflected by the to-be-detected region into a short wave infrared fluorescence image signal and a visible light image signal; the display mechanism is used for displaying the visible light image signal and the short wave infrared fluorescence image signal in a human eye visible mode; the control mechanism is used for regulating and controlling the infrared light source and the visible light source.

2. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the visible light source and the infrared light source are respectively and independently connected with the control mechanism and can be independently controlled.

3. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the optical fiber cable comprises a light guide beam and an image transmission beam which are arranged in parallel in the detection pipe, and the light guide beam and the image transmission beam can transmit optical signals in the wave band of 350-2500 nm.

4. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the imaging objective lens comprises a plurality of micro lenses which are sequentially arranged along the transmission direction of light, wherein the diameter of the imaging objective lens is 0.4-10 mm.

5. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the first end of detecting tube has internal thread structure, the shell have with internal thread structure assorted external screw thread structure, the first end of detecting tube with the shell passes through threaded connection's mode and is connected.

6. The broad spectrum fluorescence endoscope apparatus of claims 1 or 5, wherein: the part of the detection tube close to the first end is provided with a corrugated tube structure which can be stretched and restored along the length direction of the detection tube under the action of external force.

7. The broad spectrum fluorescence endoscope apparatus of claims 1 or 5, wherein: the second end of the detecting tube is provided with a detecting head, the detecting head is connected with the detecting tube in a threaded connection mode and can be detached, a plurality of cylindrical containing cavities which are arranged in parallel are arranged in the detecting head, and each imaging objective lens is correspondingly embedded in one containing cavity.

8. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the image detection mechanism comprises a camera, the camera is a wide-spectrum sensing camera capable of detecting visible light and short-wave infrared fluorescence simultaneously, or the image detection mechanism comprises a visible light image camera for detecting visible light and a short-wave infrared image camera for detecting short-wave infrared fluorescence.

9. The broad spectrum fluorescence endoscopic device of claim 8, wherein: the camera comprises a detector, and an imaging optical device and a filtering mechanism which are arranged at the receiving end of the detector, wherein the filtering mechanism is at least used for filtering infrared exciting light, the imaging optical device is at least used for collecting reflected visible light and short wave infrared fluorescence, and focusing the collected reflected visible light and short wave infrared fluorescence on the detector to form an optical image.

10. The broad spectrum fluorescence endoscopic device of claim 1, wherein: the display mechanism comprises a display, and the display is used for displaying a visible light image and a short wave infrared fluorescence image.

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