CN201476980U

CN201476980U - Device for sampling and testing

Info

Publication number: CN201476980U
Application number: CN 200920188718
Authority: CN
Inventors: 王滨
Original assignee: SUZHOU R-PROTAGEN Co Ltd
Current assignee: Suzhou DiagVita Biotechnology Co., Ltd.
Priority date: 2009-08-20
Filing date: 2009-08-20
Publication date: 2010-05-19
Anticipated expiration: 2019-08-20

Abstract

The utility model discloses a device for sampling and testing, which comprises a reactor and a reaction tube which are sleeved with each other and can be separated, wherein the reactor comprises an outer case with an inner cavity, the outer case can be extruded to deform, the inner cavity of the outer case is provided with a liquid storage bag capable of being extruded to break, and the outer case is also provided with a hole communicated with the inner cavity and is connected with a sampling tube communicated with the hole; the outer case is provided with a sampler communicated with the tube cavity of the sampling tube, the liquid storage bag is extruded to break when extruding the outer case, the stored liquid flows out and flows to the sampling tube through the hole, and then reaches to the sampler with sample, the stored liquid reacts with the liquid in the liquid storage bag, in this way, the test result can be immediately obtained on the sampling site, or the sample can be pre-processed on the sampling site, and then is sent to the laboratory for further analysis, so the performance change or degradation of the sample caused by the instability is effectively avoided.

Description

The device of sample collecting and testing

Technical field

The utility model relates to a kind of device of chemical analysis chemical examination, is specifically related to a kind of device of sample collecting and testing.

Background technology

In medical domain, the conventional method that carries out chemical analysis chemical examination be clinical or spot sampling after deliver to the laboratory again and do further analytical test, in this process, guarantee the quality of sample, precise results not contaminated and chemical examination is very difficult behind the sample collecting, in addition, because temporal delay will cause sample test result's accuracy and reliability to reduce, and to directly obtain result of laboratory test at the scene, perhaps after collecting sample, in time sample is carried out pre-service, and then be sent to the laboratory and carry out further assay, present apparatus also is difficult to finish.

Summary of the invention

The purpose of this utility model be to provide a kind of can on-the-spot device to sample collecting, processing, chemical examination, can directly obtain experimental result by this device, perhaps on instrument, read the result by further analysis.

In order to reach above purpose, the technical solution adopted in the utility model is: a kind of device of sample collecting and testing, this device comprises socket-connect also separable reactor and reaction tube, described reactor comprises the shell body with inner chamber, but described shell body is crimp, be equipped with in the inner chamber of described shell body and can push damaged reservoir, described shell body is provided with the perforate with described intracavity inter-connection, be connected with the sampling pipe that is connected with described perforate on the described shell body, has the sampling thief that is connected with this sampling pipe tube chamber on the described sampling pipe, when described reactor and described reaction tube socket-connected together, described sampling thief placed described reaction tube.

Described shell body comprises that the bottom has the web member that the cover of opening, upper end are sealed described opening, the described reservoir that pushes breakage places in the described cover, but described cover is crimp, offer described perforate on the lower surface of described web member, described sampling pipe inserts described perforate regularly, and described reaction tube is enclosed within on the lower end of described web member separably.

The upper surface of described web member in described cover is V-shaped, and the minimum point of this V-arrangement upper surface is provided with opening, and this opening has formed the last aperture of described perforate.

Around a circle flank is arranged, between the bottom of a described circle flank and described web member spatial accommodation is arranged on the bottom of described web member, when described reaction tube was enclosed within the lower end of described web member, the mouth of pipe of described reaction tube was arranged in described spatial accommodation.

Described sampling thief is a swab, and this swab places on the termination of described sampling pipe.

Described sampling thief is a spiral sampling awl, and this spiral sampling awl places on the termination of described sampling pipe.

Described reservoir is to be made by the material of cracky.

The material of described cracky is rigid plastic or glass.

Described cover is to be made by soft plastic.

Described reaction tube is a transparent tube.

Because the utility model has adopted above technical scheme, its advantage is: in the device of sample collecting and testing, but can push damaged reservoir and place the shell body of crimp, then push shell body, reservoir is crushed, the liquid that stores flows out, flow in the sampling pipe through perforate, arrive on the sampling thief then, gathering on the sampling thief has sample, and then sample can react with the liquid in the reservoir, just can immediately obtain experimental result at the sample collecting scene like this, perhaps earlier sample is carried out pre-service at collection site, be sent to the laboratory then and further analyze, can avoid effectively like this that sample is unstable, and performance change or degraded take place, when reactor and reaction tube socket-connect, sampling thief places reaction tube, so on the one hand, can avoid effectively sampling thief transportation or carry in the process contaminated, on the other hand in some occasion, the reaction of liquid is carried out in reaction tube in sample and the reservoir, can guarantee the accurate of experimental result.

Description of drawings

Accompanying drawing 1 is the cross-sectional schematic of the utility model embodiment one, and wherein sampling thief adopts swab;

Accompanying drawing 2 is the cross-sectional schematic of the utility model embodiment two, and wherein sampling thief adopts spiral sampling awl.

Embodiment

Further set forth concrete structure of the present utility model below in conjunction with accompanying drawing.

Referring to illustrated in figures 1 and 2, a kind of device of sample collecting and testing, this device comprises socket-connect also separable reactor 1 and reaction tube 2, reactor 1 comprises the shell body 11 with inner chamber 12, be equipped with in the inner chamber of shell body and can push damaged reservoir 13, but shell body 11 is crimp, by extruding shell body 11, reservoir 13 stressed breakages, the liquid that stores in the reservoir 13 flows out in the shell body 11, shell body 11 is provided with the perforate 14 that is connected with inner chamber 12, be connected with the sampling pipe 15 that is connected with perforate 14 on the shell body 11, then after reservoir 13 breakages, liquid in the reservoir 13 flow in the tube chamber 16 of sampling pipe 15 through perforate 14, has the sampling thief 17 that is connected with sampling pipe tube chamber 16 on the sampling pipe 15, when reactor 1 and reaction tube 2 socket-connect together, sampling thief 17 places reaction tube 2, sampling thief 17 is used to gather sample, then the liquid in the reservoir 13 is when the tube chamber 16 of sampling pipe 15 flow on the sampling thief 17, liquid in the reservoir 13 can react with the sample that collects, in order to guarantee the accurate of result of laboratory test, reaction is carried out in reaction tube 2, simultaneously, sampling thief 17 places reaction tube 2, can avoid sampling thief 17 transporting or carrying in the process contaminated effectively.By sample collecting and testing device of the present utility model; can detect sample is on-the-spot; in time obtain experimental result, perhaps by the liquid in the reservoir 13 to sample pretreatment, can do next step analysis in the laboratory later on; can reduce the chance of sample secondary pollution so widely; and can avoid sample unstable generation performance change or degraded effectively, for example, RNA is easy to degraded; mix behind the spot sampling at once, can stop the degraded of RNA with protective agent in the reservoir 13.

In specific embodiment one and two, shell body 11 designs are following structure, shell body 11 is had the cover 111 of opening by the bottom, the upper end is sealed the web member 112 of cover 111 upper sheds and is formed, can push damaged reservoir 13 places in the cover 111, but cover 111 is crimp, cover 111 integral body or part are made by flexible material, for example, can make by soft plastic, reservoir 13 can be made by the material of cracky, for example, can be made by rigid plastic or glass, preferably, can be made by transparent rigid plastic, web member 112 can adopt rubber or plastics or timber or metal to make, and offers perforate 14 on the lower surface of web member 112, sampling pipe 15 inserts perforate 14 regularly, and reaction tube 2 is enclosed within on the lower end of web member 112 separably.In specific embodiment one, sampling thief 17 is a swab, and this swab places on the termination of sampling pipe 15, swab by absorbent cotton, do not have medical materials such as imitative cloth, sponge and make, swab generally is applicable to the sample on surfaces such as gathering microorganism or tableware, medicine equipment; In specific embodiment two, sampling thief 17 is spiral sampling awl, and this spiral sampling awl places on the termination of sampling pipe 15, and spiral sampling awl is applicable to gathering solid sample such as ight soil.Reaction tube 2 can be open or sealing away from the lower end of web member 112, this can decide according to the actual requirements, the lower end of reaction tube 2 is designed to seal, and as shown in Figure 1, the reaction that can guarantee liquid in the sample gathered and the reservoir 13 effectively is to carry out in the space of sealing, reduce and disturb, if the lower end of reaction tube 2 is designed to open, as shown in Figure 2, then in some application scenario, can or connect test strips at the following termination test tube of reaction tube 2, can further analyze.

In order to guarantee that the liquid in the reservoir 13 can successfully all flow on the sampling thief 17, the upper surface of web member 112 in cover 111 is V-shaped, and the minimum point of this V-arrangement upper surface is provided with opening, and this opening has formed the last aperture of perforate 14.After reservoir 13 fragmentations, liquid wherein can successfully converge to the opening at minimum point place through the V-arrangement face, thereby all flows in the sampling pipe 15.

In order to prevent that reaction tube 2 from being polluted, center on the bottom of web member 112 a circle flank 113 is arranged, between the bottom of one circle flank 113 and web member 112 spatial accommodation 114 is arranged, when reaction tube 2 is enclosed within the lower end of web member 112, the mouth of pipe of reaction tube 2 is arranged in spatial accommodation 114, by flank 113, but blocks dust or other foreign material enter the mouth of pipe of reaction tube 2.

In some occasion, reaction tube 2 is designed to transparent tube, and direct observation experiment result in chromogenic reaction perhaps in fluorescence reaction, can be communicated with reaction tubes 2 with sampling thief 17 and put into instrument, observed result like this.

To sum up, the apparatus structure of sample collecting and testing of the present utility model is simple, can finish collection continuously, handle, react, obtain a result, step such as sample transhipment, can be widely used in biochemical enzymes (as luciferase, blood sample analysis, DNA sampling, body fluid, ight soil sampling etc.), microbe culture and sample transhipment, food microorganisms, germ detection, the fields such as the germ detection of clinical sample analyzed alive.

The use of the utility model device is described with regard to different application scenarios below:

1, the detection of microbe culture

Reactor 1 is separated with reaction tube 2, gather micro-biological samples with 17 swabs of the sampling thief on the reactor 1, then reactor 1 and reaction tube 2 are overlapped again and connect, extruding shell body 11, reservoir 13 is crushed, and liquid flows out, through flowing to behind perforate 14 and the sampling pipe 15 on sampling thief 17 swabs, example reaction with gathering can detect the microbial growth situation.

2, the detection of microbial contamination and surface cleanliness

The ATP quick detection reagent of in reservoir 13, packing into solution, with reservoir squeeze broken after, reagent solution arrives on sampling thief 17 swabs, behind the wetting swab, solution enters in the reaction tube 2, then reactor 1 and reaction tube 2 are separated, gather the sample on microorganism or tableware surface with wetting swab, then again reactor 1 and reaction tube 2 are reconnected, shake reaction tube 2 gently, make the abundant mixing reaction of sample and reactant liquor, observed result, the principle of ATP fast detecting can produce fluorescence when being this firefly luciferase oxyluciferin, and this reaction needed ATP provide energy, and ATP is a kind of important energy chemical substance in the biosome (comprising microorganism), when firefly luciferase and fluorescein are all excessive, the concentration of the generation of fluorescence and ATP is directly proportional in certain concentration range, just can detect ATP concentration by detecting fluorescence like this, thereby detect the contamination by micro situation.

3, the processing of solid sample

Separate reactor 1 and reaction tube 2 are gathered solid sample such as ight soil with the sampling thief 17 spiral sampling awls of reactor 1, and reactor 1 and reaction tube 2 are reconnected, and squeeze broken reservoir 13, and liquid flows out on the sampling awl, reacts with fixed sample.

4, the collection of DNA, RNA, blood sample, microbiological specimens and transhipment

Separate reactor 1 and reaction tube 2; sampling thief 17 swabs with reactor 1 are gathered blood, saliva, seminal fluid, cell equal samples; reactor 1 and reaction tube 2 are reconnected; for unsettled sample, reservoir 13 is crowded broken, the protective agent liquid of storage and sample reaction; thereby the sample of gathering is protected; for stable sample, also can directly the sample of gathering be sent to and detect the ground detection, this device relatively is fit to occasions such as legal medical expert, medical test.

5, the medicine equipment cleaning performance is estimated

Separate reactor 1 and reaction tube 2, the medical apparatus surface that cleaned with the sampling thief 17 swab wipings of reactor 1, after having gathered sample, reactor 1 and reaction tube 2 are reconnected, squeeze reservoir 13 broken, liquid that stores such as hydration indenes three bronze medals, copper sulphate, arrive on the sampling thief,, observe change in color with example reaction, and with color board contrast, detect the situation of residual protein on the medicine equipment.

Claims

1. the device of a sample collecting and testing, it is characterized in that: this device comprises socket-connect also separable reactor and reaction tube, described reactor comprises the shell body with inner chamber, but described shell body is crimp, be equipped with in the inner chamber of described shell body and can push damaged reservoir, described shell body is provided with the perforate with described intracavity inter-connection, be connected with the sampling pipe that is connected with described perforate on the described shell body, has the sampling thief that is connected with this sampling pipe tube chamber on the described sampling pipe, when described reactor and described reaction tube socket-connected together, described sampling thief placed described reaction tube.

2. the device of sample collecting and testing according to claim 1, it is characterized in that: described shell body comprises that the bottom has the web member that the cover of opening, upper end are sealed described opening, the described reservoir that pushes breakage places in the described cover, but described cover is crimp, offer described perforate on the lower surface of described web member, described sampling pipe inserts described perforate regularly, and described reaction tube is enclosed within on the lower end of described web member separably.

3. the device of sample collecting and testing according to claim 2, it is characterized in that: the upper surface of described web member in described cover is V-shaped, and the minimum point of this V-arrangement upper surface is provided with opening, and this opening has formed the last aperture of described perforate.

4. according to the device of claim 2 or 3 described sample collecting and testings, it is characterized in that: centering on the bottom of described web member has a circle flank, between the bottom of a described circle flank and described web member spatial accommodation is arranged, when described reaction tube was enclosed within the lower end of described web member, the mouth of pipe of described reaction tube was arranged in described spatial accommodation.

5. the device of sample collecting and testing according to claim 1, it is characterized in that: described sampling thief is a swab, and this swab places on the termination of described sampling pipe.

6. the device of sample collecting and testing according to claim 1 is characterized in that: described sampling thief is a spiral sampling awl, and this spiral sampling awl places on the termination of described sampling pipe.

7. the device of sample collecting and testing according to claim 1, it is characterized in that: described reservoir is to be made by the material of cracky.

8. the device of sample collecting and testing according to claim 7, it is characterized in that: the material of described cracky is rigid plastic or glass.

9. the device of sample collecting and testing according to claim 2, it is characterized in that: described cover is to be made by soft plastic.

10. the device of sample collecting and testing according to claim 1, it is characterized in that: described reaction tube is a transparent tube.