CN201211189Y - Watch type no-wound optical acoustic blood-sugar monitoring instrument - Google Patents
Watch type no-wound optical acoustic blood-sugar monitoring instrument Download PDFInfo
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- CN201211189Y CN201211189Y CNU2008201130924U CN200820113092U CN201211189Y CN 201211189 Y CN201211189 Y CN 201211189Y CN U2008201130924 U CNU2008201130924 U CN U2008201130924U CN 200820113092 U CN200820113092 U CN 200820113092U CN 201211189 Y CN201211189 Y CN 201211189Y
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Abstract
The utility model relates to a watch type non-invasive optical acoustic blood sugar monitor. The inside of a watch type shell is provided with a display screen, a control button, a controller, a battery and a measuring box, an acoustic insulated layer, an acoustic backing, a semiconductor laser tube, a Fourier lens, a light transmission protective film and a hollow multi-ring array sensor are all-in-one packaged in the measuring box so as to form an integrated coaxial confocal structure. The watch type shell is provided with a watch belt worn on a wrist of a detector, and an optical acoustic excitation source and an optical path lens system generate a focused laser beam to pass through the hollow multi-ring array sensor and irradiate blood vessels in the wrist, thereby realizing the optical acoustic blood sugar detection with continuous A type dynamic focus scanning and providing optical acoustic blood sugar results of a plurality of points along the depth direction of the wrist. The monitor has the advantages of small structure, convenient carrying, simple operation, the realization of the real time monitoring of the optical acoustic blood sugar, no wound during detection, unnecessary blood extraction and test paper supply and the avoidance of cross infection and environmental influence.
Description
Technical field
This utility model relates to biomedical measurement and technical field of medical instruments, is specifically related to a kind of watch type non-invasive light sound blood sugar monitoring instrument.
Background technology
Blood sugar test still generally adopts the mediatory type means that wound or Wicresoft are arranged at present, this mode needs micro-end blood and corresponding reagent paper slightly, and the development in future direction should be the Woundless blood sugar detection technique of non-mediatory type, for example optical instruments such as optoacoustic analytic process, spectra methods, Raman spectrum analysis method, light scattering Zymography and light polarization Zymography.Also there are a lot of difficulties in current optoacoustic analytical method, and as owing to need accomplish the detection that can't harm, the energy of incident laser can not surpass threshold values, and the launching efficiency that therefore effectively improves optoacoustic is a problem that needs solution in a hurry.In addition, be to adopt solid state laser more than the optoacoustic detection as excitaton source, there is certain difficulty in the integrated and miniaturization of system.
Calendar year 2001 Z.Zhao and R.Myllyla, " Photoacoustic dete rmination ofglucose concentration in whole blood by a near-infrared laser diode " Proc.SPIE, 4256,77-83,2001. reported the measuring method of the light sound blood sugar concentration that excites based on the near-infrared laser diode, but it is clinical that the detection method of this forward mode is difficult to be applied to, and fail to realize confocal arrangement, the sensitivity of system is very low, and the photoacoustic signal that collects needs average thousands of times.A.A.Bednov in 2003, E.V.Savateeva, A.A.Oraevsky, " Glucose monitoring in wholeblood by measuring laser-induced acoustic profiles " Proc.SPIE, 4960,21-29,2003. reported light sound blood sugar detection method based on the side direction detection mode, adopted high-power Nd:YAG laser instrument as excitaton source, the photoacoustic signal that collects needs on average hardly, but the solid state laser of large volume can't be realized real miniaturization and practicality [non-patent literature 2].And also all there is a problem in said method, owing to be that single detector is as transducing part all, photo-acoustic excitation and sensing fail to realize the coaxial confocal structure, therefore the efficient of photo-acoustic excitation and detection is not high, need more powerful solid state laser that the optoacoustic excitation energy is provided, or need thousands of signals on average just improve signal to noise ratio, and the solid state laser of large volume can't realize encouraging the integrated and miniaturization with sensing, signal averaging repeatedly greatly reduces the temporal resolution of system, forward direction and edgewise detection mode all lack the convenience of practical operation, and actual popularizing application prospect has been subjected to very big restriction.
Summary of the invention
The technical problems to be solved in the utility model provide a kind of structure small and exquisite, be easy to carry, watch type non-invasive blood sugar monitoring instrument easy and simple to handle, the light sound blood sugar monitoring result in a plurality of sites of wrist depth direction can be provided simultaneously.
For solving the problems of the technologies described above, the technical solution of the utility model is: a kind of watch type non-invasive light sound blood sugar monitoring instrument, it is characterized in that: be provided with display screen and control knob on the surface of shell, the bottom surface of shell is the multi-layered bonded plate, measuring box is placed on the multi-layered bonded plate, is provided with the acoustics insulating barrier and the sound absorption pad of hollow in measuring box; Top at the acoustics insulating barrier is provided with semiconductor laser tube, is provided with fourier transform lens below semiconductor laser tube, and the below of fourier transform lens is provided with light transmission protecting film and is installed in hollow multi-ring array pick off on the multi-layered bonded plate; The center of semiconductor laser tube, fourier transform lens, light transmission protecting film and hollow multi-ring array pick off all is positioned on the same axis, integrated being packaged in the measuring box, constitute incorporate coaxial confocal structure, improve investigation depth when can effectively reduce the laser energy requirement; Be provided with controller and battery in the side of measuring box, each ring of hollow multi-ring array pick off is connected with the binding post of controller respectively by lead.Described shell is a watch style, and the watchband that is worn on detected personnel's wrist is housed.Described semiconductor laser tube is the quasiconductor pulsed laser diode, is operated in the one or more wavelength of ultraviolet to the infra-red range.Described semiconductor laser tube and fourier transform lens form the photo-acoustic excitation source and the light path lens combination produces the laser beam that focuses on, and passes the hollow internal ring of light transmission protecting film and hollow multi-ring array pick off, the blood vessel in the directive wrist.Planar array that described hollow multi-ring array pick off is a hollow or concavo-convex battle array adopt piezoelectric, comprise Lithium metaniobate, composite, piezoelectric ceramics or the making of PVDF thin film; Hollow multi-ring array pick off adopts dorsad that the serial or parallel of pattern receives photoacoustic signal in real time, realizes that the light sound blood sugar of continuous A type dynamic focusing scanning is surveyed, and the light sound blood sugar result in a plurality of sites of wrist depth direction is provided.
Work process of the present utility model is: under controller triggers, the semiconductor laser tube excitation produces pulse laser, its wavelength, pulsewidth and repetition rate can be selected as required, after laser energy focuses on by the light path collimated, see through protecting film and be radiated blood vessel wrist skin under, functional groups such as blood glucose absorption luminous energy excites the generation photoacoustic signal; Controller triggers multi-ring array pick off mode detection photoacoustic signal dorsad simultaneously, realizes exciting and sensing of photoacoustic signal; By the optoacoustic data that certain algorithm process collects, can realize the continuous A type dynamic focusing scanning probe of light sound blood sugar at depth direction, obtain the light sound blood sugar result in a plurality of sites of wrist depth direction.
The beneficial effects of the utility model are:
1) this utility model method with the receiving mode dorsad of optoacoustic, excite and sensing integrated processing, effectively realized the watch style system structure of miniaturization and practicability, have structure small and exquisite, be easy to carry, easy and simple to handle, the real-time monitoring that can realize light sound blood sugar, do not have wound, need not extract blood and reagent paper is provided, avoid the advantage of the influence of cross infection and environment when detecting.
2) this utility model forms the coaxial confocal structure with photo-acoustic excitation source, light path lens combination and multi-ring array pick off, can greatly improve exciting and sensing efficient of optoacoustic, effectively reduce and improve investigation depth when laser energy requires, realize the continuous A type dynamic focusing scanning probe of light sound blood sugar, the light sound blood sugar result in a plurality of sites of wrist depth direction is provided.
3) this utility model adopts cheap semiconductor laser tube to realize the light sound blood sugar monitoring, and the cost of each assembly is lower, so the cost of single unit system is also relatively low, is easy to application.
Description of drawings
Fig. 1 is this utility model structural upright sketch map.
Fig. 2 is this utility model structure (the A-A section of Fig. 1) sketch map.
Fig. 3 is the wiring schematic diagram of multi-ring array pick off.
Fig. 4 is worn on the sketch map of wrist for this utility model.
The specific embodiment
Be described further of the present utility model below in conjunction with drawings and Examples.
Embodiment: a kind of watch type non-invasive light sound blood sugar
Monitor is provided with display screen 11 and control knob 18 on the surface of watch style shell 13, the bottom surface of shell 13 is a multi-layered bonded plate 12, and measuring box 7 is placed on the multi-layered bonded plate 12.In measuring box 7, be provided with the acoustics insulating barrier 6 and the sound absorption pad 5 of hollow.Be provided with quasiconductor pulsed laser diode 155G4S14X at the top of acoustics insulating barrier 6, Laser Components1, operation wavelength is 1550nm, and peak power is 45W, and pulsewidth is 150ns, and single pulse energy is about 6.75uJ, and dutycycle DF is 0.1%.Be provided with fourier transform lens 2 below quasiconductor pulsed laser diode 1, the below of fourier transform lens 2 is provided with light transmission protecting film 3 and is installed in hollow multi-ring array pick off 4 on the multi-layered bonded plate 12; The center of semiconductor laser tube 1, fourier transform lens 2, light transmission protecting film 3 and hollow multi-ring array pick off 4 all is positioned on the same axis 15, and integrated being packaged in the measuring box 7 constitutes incorporate coaxial confocal structure.Hollow multi-ring array pick off 4 is the planar array or the concavo-convex battle array of hollow, the employing piezoelectric ceramics is made, the work centre frequency is 2.5MHz, the number of ring is 6, be designed to the equally spaced planar rings battle array of the homalographic structure of hollow, ring spacing is not more than half-wavelength, and wherein the velocity of sound is decided to be 1500m/s, each ring is connected with the binding post 20 of controller 9 respectively by lead 19, realizes the sensing and the processing of photoacoustic signal.Light transmission protecting film 3 has printing opacity and water-proof function, can protect inner optics; Acoustics insulating barrier 6 is used to prevent that ultrasonic energy from reaching shell 13 and causing the reflection interference signal.Be provided with controller 9 and battery 10 in the side of measuring box 7.
Watch style shell 13 is equipped with the watchband 17 that is worn on detected personnel's wrist 8, quasiconductor pulsed laser diode 1 and fourier transform lens 2 are formed the laser beam 14 of photo-acoustic excitation source and light path lens combination generation focusing, pass the hollow internal ring of light transmission protecting film 3 and hollow multi-ring array pick off 4, the blood vessel 16 in the directive wrist 8; Hollow multi-ring array pick off 4 adopts dorsad that the serial or parallel of pattern receives photoacoustic signal in real time, realizes that the light sound blood sugar of continuous A type dynamic focusing scanning is surveyed, and the light sound blood sugar result in a plurality of sites of wrist depth direction is provided.
Claims (4)
1. watch type non-invasive light sound blood sugar monitoring instrument, it is characterized in that: be provided with display screen (11) and control knob (18) on the surface of shell (13), the bottom surface of shell (13) is multi-layered bonded plate (12), measuring box (7) is placed on the multi-layered bonded plate (12), is provided with the acoustics insulating barrier (6) and the sound absorption pad (5) of hollow in measuring box (7); Be provided with semiconductor laser tube (1) at the top of acoustics insulating barrier (6), be provided with fourier transform lens (2) in the below of semiconductor laser tube (1), the below of fourier transform lens (2) is provided with light transmission protecting film (3) and is installed in hollow multi-ring array pick off (4) on the multi-layered bonded plate (12); The center of semiconductor laser tube (1), fourier transform lens (2), light transmission protecting film (3) and hollow multi-ring array pick off (4) all is positioned on the same axis (15), and integrated being packaged in the measuring box (7) constitutes incorporate coaxial confocal structure; Be provided with controller (9) and battery (10) in the side of measuring box (7), each ring of hollow multi-ring array pick off (4) is connected with the binding post (20) of controller (9) respectively by lead (19); Hollow multi-ring array pick off (4) adopts pattern reception photoacoustic signal dorsad, realizes that the light sound blood sugar of continuous A type dynamic focusing scanning is surveyed, and the light sound blood sugar result in wrist (8) a plurality of sites of depth direction is provided.
2. watch type non-invasive light sound blood sugar monitoring instrument according to claim 1 is characterized in that: described shell (13) is a watch style, and the watchband (17) that is worn on detected personnel's wrist (8) is housed.
3. watch type non-invasive light sound blood sugar monitoring instrument according to claim 1 is characterized in that: described semiconductor laser tube (1) is the quasiconductor pulsed laser diode, is operated in the one or more wavelength of ultraviolet to the infra-red range.
4. watch type non-invasive light sound blood sugar monitoring instrument according to claim 1 is characterized in that: described hollow multi-ring array pick off (4) is the planar array of hollow or concavo-convex battle array.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008201130924U CN201211189Y (en) | 2008-07-03 | 2008-07-03 | Watch type no-wound optical acoustic blood-sugar monitoring instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008201130924U CN201211189Y (en) | 2008-07-03 | 2008-07-03 | Watch type no-wound optical acoustic blood-sugar monitoring instrument |
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| CN201211189Y true CN201211189Y (en) | 2009-03-25 |
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| CNU2008201130924U Expired - Lifetime CN201211189Y (en) | 2008-07-03 | 2008-07-03 | Watch type no-wound optical acoustic blood-sugar monitoring instrument |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100558297C (en) * | 2008-07-03 | 2009-11-11 | 江西科技师范学院 | Watch type non-invasive light sound blood sugar monitoring instrument |
| CN102018517A (en) * | 2009-09-17 | 2011-04-20 | 林紫谊 | Non-invasive glucometer |
| CN102113883A (en) * | 2010-01-05 | 2011-07-06 | 精工爱普生株式会社 | Biological information detector and biological information measuring device |
| ES2538040A1 (en) * | 2013-12-16 | 2015-06-16 | Ineuron Health Systems, S.L. | Device, system and method for the non-invasive measurement of physiological data (Machine-translation by Google Translate, not legally binding) |
| CN105559794A (en) * | 2016-02-23 | 2016-05-11 | 杨立峰 | Wearable noninvasive dynamic blood glucose monitor based on photo-acoustic spectrometry features |
| CN107320113A (en) * | 2017-07-27 | 2017-11-07 | 上海交通大学 | The differential type non-invasive glucose monitor and method of environmental disturbances and vibration can be resisted |
| WO2024167465A1 (en) * | 2023-02-09 | 2024-08-15 | Agency For Science, Technology And Research | Device and method for externally measuring blood flow |
-
2008
- 2008-07-03 CN CNU2008201130924U patent/CN201211189Y/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100558297C (en) * | 2008-07-03 | 2009-11-11 | 江西科技师范学院 | Watch type non-invasive light sound blood sugar monitoring instrument |
| CN102018517A (en) * | 2009-09-17 | 2011-04-20 | 林紫谊 | Non-invasive glucometer |
| CN102113883A (en) * | 2010-01-05 | 2011-07-06 | 精工爱普生株式会社 | Biological information detector and biological information measuring device |
| CN102113883B (en) * | 2010-01-05 | 2015-02-18 | 精工爱普生株式会社 | Biological information detector and biological information measuring device |
| ES2538040A1 (en) * | 2013-12-16 | 2015-06-16 | Ineuron Health Systems, S.L. | Device, system and method for the non-invasive measurement of physiological data (Machine-translation by Google Translate, not legally binding) |
| CN105559794A (en) * | 2016-02-23 | 2016-05-11 | 杨立峰 | Wearable noninvasive dynamic blood glucose monitor based on photo-acoustic spectrometry features |
| CN105559794B (en) * | 2016-02-23 | 2018-03-23 | 杨立峰 | A kind of Wearable hurtless measure Dynamic Blood Glucose Monitoring instrument based on optoacoustic spectrum signature |
| CN107320113A (en) * | 2017-07-27 | 2017-11-07 | 上海交通大学 | The differential type non-invasive glucose monitor and method of environmental disturbances and vibration can be resisted |
| WO2024167465A1 (en) * | 2023-02-09 | 2024-08-15 | Agency For Science, Technology And Research | Device and method for externally measuring blood flow |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Effective date of abandoning: 20080703 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |