CN208721691U - A kind of luminescent chemical immunity analysis instrument - Google Patents

Abstract

The utility model discloses a kind of luminescent chemical immunity analysis instruments, including reagent sample device, sample incubation detection device, being arranged between reagent sample device and sample incubation detection device from top to bottom has the first turntable, the sampling clamp portion of liftable rotation and the second turntable, crawl station is provided on first turntable, interactive station is provided on second turntable, the first turntable and the second turntable can rotate；The rotatable spy of the handgrip in sampling clamp portion get be located at crawl station reaction tube, positioned at interaction station reaction tube and disk can be incubated for by being transferred in sample incubation detection device added with the reaction tube of reagent sample.The utility model is able to ascend by cooperating the space layout between reagent sample device, sample incubation detection device, the first turntable, the second turntable and sampling clamp portion the cooperation efficiency of all parts in detection process, promotes detection speed.

Description

A kind of luminescent chemical immunity analysis instrument

Technical field

The utility model relates to immunoassay fields, and in particular to a kind of luminescent chemical immunity analysis instrument.

Background technique

Immunology detection is mainly a kind of means detected using the specific reaction of antigen and antibody, since it can Detection signal is amplified and be shown using isotope, enzyme, chemiluminescent substance etc., therefore it is commonly used for detecting albumen The micro substances such as matter, hormone.Since the sixties in last century, immunoassay is just widely used in scientific research and clinical field.From The radioimmunology most started gradually develops to enzyme-linked immunization, the Chemiluminescence immunoassay until being widely used at present.

Chemiluminescence immune assay is to combine chemiluminescence or bioluminescence with immune response, micro anti-for detecting A kind of former or antibody novel markings immunoassay.Chemiluminescent mechanism is certain compounds (luminous agent or luminous bottom Object) can use one chemical reaction generate energy make its product molecule or Intermediates molecule rise to electronics swash state. When this product molecule or intermediate state molecule fail to ground state, is released energy and (shone) in the form of emitting photon.It is immune to survey It surely is the method that micro substance in sample is measured using antigen precursor reactant.

The more traditional radio-immunity environmental protection of Chemiluminescence Immunoassay, safety, compared with enzyme linked immunological high sensitivity, detection range It is wide.The features such as chemiluminescence immunoassay detection is environmentally friendly, quick, accurate has obtained the generally approval of people, it has also become clinic is exempted from present The main means of epidemic disease diagnosis.

The detection speed of luminescent chemical immunity analysis instrument instantly is not high now, existing to solve the problems, such as detection speed Technology introduces the channels such as a plurality of parallel sense channel, incubation, liquid feeding to improve detection speed, however because each channel can Different errors are introduced, as soon as cause sample that will introduce error when handling through every process channel, the thus presence of multichannel The problem of biggish accumulated error can be generated, cause speed and detection accuracy that can not and deposit.

For this purpose, solving inspection the utility model proposes a kind of Full-automatic chemiluminescence analyzer for improving detection speed The not high problem of degree of testing the speed, while also solving a plurality of sense channel or incubation and liquid feeding channel difference and lead to asking for error Topic.

Utility model content

The purpose of this utility model is to provide a kind of luminescent chemical immunity analysis instruments, solve the above problems.

The utility model is achieved through the following technical solutions:

A kind of luminescent chemical immunity analysis instrument, including having the reagent sample of reagent storage unit and sample storage unit dress simultaneously It sets, sample incubation detection device, being arranged between reagent sample device and sample incubation detection device from top to bottom has sample-adding originally The sampling clamp portion and magnetic bead and reagent will be added to be used for after the completion instead that the first turntable, the liftable of reaction tube transfer afterwards rotate Should pipe transfer the second turntable, be provided with crawl station on the first turntable, interactive station be provided on the second turntable, One turntable and the second turntable can rotate；The reaction for being located at crawl station is got in the rotatable spy of the handgrip in sampling clamp portion Pipe, positioned at interaction station reaction tube and can will be transferred in sample incubation detection device added with the reaction tube of reagent sample, When implementation, when the reaction tube on the first turntable turns to crawl station, the handgrip in sampling clamp portion will be located at crawl station The reaction tube be transferred to the second turntable, when the reaction tube on the second turntable be located at interaction station when, by the reaction tube Crawl carries out incubation detection into this incubation detection device.

The utility model is by by reagent sample device, sample incubation detection device, the first turntable, the second turntable Space layout cooperation between sampling clamp portion, is able to ascend the cooperation efficiency of all parts in detection process, promotes detection Speed.It actually further include existing in the utility model for controlling the control system of all parts operation, control system and each A corresponding component connection that need to be controlled.

Reagent sample device in the utility model means that reagent and sample are integrated in one and separate the device of storage, In one embodiment, reagent sample device has reagent storage unit and sample storage unit, reagent storage unit and sample storage unit simultaneously It is arranged at by being capable of relative motion on different motor-driven different turntables.

Sample incubation detection device means the device that incubation, detection function are integrated.

Sampling clamp portion further includes pedestal, and rotary shaft is provided on pedestal, and the upper end of rotary shaft is arranged in handgrip, and sampling is grabbed Hand is grabbed the cleaning disk, the incubation disk of sample incubation test section, the first turntable of sample incubation test section by rotary shaft Interaction station, the useless pipe blanking station on the first turntable connect on station, the second turntable.Wherein sampling clamp can only Reaction tube is caught from the first turntable, cleaning disk interaction position, and sampling clamp can only abandon mouth toward the useless pipe of the first turntable and put the Useless pipe after one turntable diluted sample, the interaction position for being incubated for disk and the second turntable can pass in and out reaction tube, wherein in second Turntable interaction position is fixed, and being incubated for disk interaction position is that a camber line has multiple interaction locations.Compared with prior art, so arranged Advantage is to connect the first turntable and the second turntable and sample incubation test section by sampling clamp portion, Make its several component function single, stability is better, more conducively improves the efficiency of various pieces.

Other three stations are evenly arranged with also along its circumferential direction in addition to grabbing station in the turntable body of first turntable: Sample waiting station plus Sample Dilution mix station；In the turntable body of second turntable in addition to the interaction station of setting, edge is gone back Its circumferential direction be evenly arranged with other three stations: reagent needle liquid feeding station, ultrasonic needle liquid feeding station, reagent mix station；The The hole offered on each station for placing response pipe is corresponded on one turntable and the second turntable.

It further include the feeding dress for being placed on blank reaction tube on the first turntable to further increase detection speed It sets, feeding device is positioned close at the first turntable.First turntable is by feeding device, and passes through specimen needle portion for sample Storage unit and reagent storage unit special reagent contact, and are then connected in the crawl process in sampling clamp portion by interaction station Face.

Further, luminescent chemical immunity analysis instrument further includes for extracting reagent from reagent storage unit and being put in reagent In the reaction tube and reagent needle portion of rotatable lifting；For extract sample from sample storage unit and sample is put in reaction tube and The specimen needle portion of rotatable lifting；For extracting the ultrasonic needle portion of magnetic bead reagent and rotatable lifting from reagent storage unit；Sample The periphery that needle portion, reagent needle portion and ultrasonic needle portion are close to reagent sample device is arranged from top to bottom.

Further, specimen needle portion is arranged between the first turntable and reagent sample device, and the setting of reagent needle portion is the Between one turntable and sampling clamp portion, ultrasonic needle portion is arranged between the second turntable and reagent sample device.This is practical new Reagent needle portion in type, specimen needle portion and ultrasonic needle portion are the prior art, and the effect in both reagent needle portion or specimen needle portion is Sample, reagent in sample reagent device is drawn out, is put into reaction tube, then cleans, then passes through sample reagent device In reagent storage unit in dilution be added reaction tube in be diluted；The effect in ultrasonic needle portion is by the examination of reagent storage unit Agent box penetrates that magnetic bead reagent is mixed into uniform suspension in latter quick 0.5~2 second and draws out quantitative suspension and comes out, It is put into reaction tube, is then cleaned.

As application No. is a kind of liquid-transfering devices of band ultrasound of CN201720892947.7 to correspond to ultrasonic needle in the prior art Portion, application No. is a kind of technical solutions for puncturing sampler of CN201220107100.0 to correspond to reagent needle portion and specimen needle portion.

Further, luminescent chemical immunity analysis instrument further includes the detection grip of liftable rotation, sample incubation detection Device includes being incubated for disk and cleaning disk, and the inside of cleaning disk is arranged in incubation disk concentric circles and the two is able to carry out relatively independent turn Dynamic, sampling clamp portion grabs reaction tube from the interaction station of the second turntable to be incubated on disk, and detection grip is used for will The reaction tube for being incubated for disk grabs cleaning disk, and the detection grip is positioned close to the second turntable simultaneously close to sample incubation At detection device.It is consistent with the structure in sampling clamp portion that grip is detected in the utility model.It is incubated for disk and cleans the opposite of disk Self-movement is carried out according to testing process needs.The relatively independent movement for being incubated for disk and cleaning disk can two different motor drivens It realizes.

It is incubated for the incubation disk interaction position for being provided with arc line type on disk disk body along its circumferential direction, is incubated on disk interaction position along its camber line Trend is provided with multiple interaction locations.Be incubated for disk disk body on be incubated for disk interaction position setting, allow sampling clamp portion with It is incubated for disk and carries out multipoint interaction.

In order to further enhance the degree of automation in the utility model, reagent identification can be also set in reagent sample device Device and specimen discerning device, to can accurately extract required reagent and sample is detected.

Sampling clamp portion, the first turntable, the second turntable, ultrasonic needle portion, specimen needle portion, reagent needle in the utility model The operating fit system in portion is: reaction tube is placed on the first turntable, and the first turntable drives reaction tube to go to and is loaded this work Position stops operating；Specimen needle portion from sample storage unit draw sample be added in reaction tube, the first turntable drive reaction tube after The continuous crawl station that turns to stops operating, and reaction tube is grabbed the examination of the second turntable by sampling clamp portion out of first turntable Agent needle liquid feeding station, reagent needle portion draw reagent from reagent storage unit and are added in reaction tube, and the second turntable continues to rotate to When ultrasonic needle liquid feeding station, the second turntable stops operating, and ultrasonic needle portion draws reagent into reaction tube from reagent storage unit, the Two turntables drive reaction tube to continue to rotate to interaction station, and reaction tube is grabbed sample incubation detection by sampling clamp portion In the incubation disk of device.After the completion of being incubated for, crawl reaction tube is into cleaning disk from incubation disk for detection grip, using clear Detection work is completed to test section after washing.

The utility model compared with prior art, has the following advantages and benefits:

The utility model will be by by reagent sample device, sample incubation detection device, the first turntable, the second turntable Space layout cooperation between sampling clamp portion, is able to ascend the cooperation efficiency of all parts in detection process, promotes detection Speed.

Detailed description of the invention

Attached drawing described herein is used to provide to further understand the utility model embodiment, constitutes the one of the application Part does not constitute the restriction to the utility model embodiment.In the accompanying drawings:

FIG. 1 is a schematic structural view of the utility model.

Fig. 2 is the utility model structure top view；

Fig. 3 is that sample incubation detection device removes the structural schematic diagram after cover board；

Fig. 4 is the structural schematic diagram of rack and disk-like structure in sample incubation detection device；

Fig. 5 is the structural schematic diagram of sample incubation detection device detection system

Fig. 6 is plate-like structure floor schematic diagram in sample incubation detection device；

Fig. 7 is handgrip seat shell in sample incubation detection device, the interior attachment structure schematic diagram for being provided with handgrip and mandril.

Specific embodiment

For the purpose of this utility model, technical solution and advantage is more clearly understood, below with reference to embodiment and attached drawing, The utility model is described in further detail, and the exemplary embodiment and its explanation of the utility model are only used for explaining this Utility model is not intended to limit the scope of the present invention.

Embodiment 1

As shown in Figure 1, reagent sample device 1018 is turntable structure, there is reagent storage unit 1008 and sample storage simultaneously Deposit portion 1009, reagent storage unit 1008 and sample storage unit 1009 are arranged at by Bu Tong motor-driven different turntables and energy Enough relative motions, different turntables are concentric circles setting.Reagent sample device 1018 in the utility model is not limited in Fig. 1 Shown in specific structure, as long as can be realized integrate reagent storage unit 1008 and sample storage unit 1009 apparatus structure it is equal It can.More specifically, reagent storage unit, which is arranged, is circumferentially evenly distributed with several reagent positions for placing reagent in inner ring；Sample Storage unit, which is arranged, is circumferentially evenly distributed with several sample bits for placing sample in outer ring.

Sample incubation detection device is similarly turntable structure.

Being arranged between reagent sample device 1018 and sample incubation detection device from top to bottom has the reaction after being loaded originally First turntable 1016 of pipe transfer, the sampling clamp portion 1001 and magnetic bead and reagent will be added to be used for after the completion instead that liftable rotates Should pipe transfer the second turntable 1017；When implementation, the grip portion in sampling clamp portion 1001 is arranged in a liftable and rotation Rotary shaft on, with realize handgrip lifting and rotation function, sampling clamp portion 1001 close to sample incubation detection device be arranged.

It is provided with crawl station 1012 on first turntable 1016, is provided with interactive station on the second turntable 1017 1003, the first turntable 1016 and the second turntable 1017 can rotate；The rotatable spy of the handgrip in sampling clamp portion 1001 takes To be located at crawl station 1012 reaction tube, positioned at interaction station 1003 reaction tube and can will be added with the reaction of reagent sample Pipe, which is transferred in sample incubation detection device, is incubated for disk, when implementation, when the reaction tube on the first turntable 1016 turns to crawl When station 1012, the reaction tube for being located at crawl station 1012 is transferred to the second turntable by the handgrip in sampling clamp portion 1001 1017, when the reaction tube on the second turntable 1017 is located at interaction station 1003, which is grabbed to this incubation and is examined It surveys in device and carries out incubation detection.

Actually further include in the utility model it is existing for control all parts operation control system, control system and The sub-control system of all parts connects, and sub-control system is connected with the driving motor of each component.

Sampling clamp portion 1001 is the prior art, such as a kind of gripper equipment of Patent No. CN201720571783.8, or Other can be realized the device of identical function.The structure of detection grip 1002 and sampling clamp portion 1001 in the utility model It is identical.

As shown in Fig. 2, circumferential uniform also along it in addition to grabbing station 1012 in the turntable body of the first turntable 1016 Be provided with other three stations: sample waiting station 1014 plus Sample Dilution mix station 1013；Second turntable 1017 turns On disk ontology in addition to the interaction station 1003 of setting, other three stations: reagent needle liquid feeding are evenly arranged with also along its circumferential direction Station 1004, ultrasonic needle liquid feeding station 1006, reagent mix station 1005；On first turntable 1016 and the second turntable 1017 The hole for placing response pipe is offered on corresponding each station.When implementation the behaviour of corresponding station function can be carried out in different station Make, such as on the disk that reaction tube is placed on the first turntable 1016 by sample waiting station 1014 in corresponding hole, when first The reaction tube is rotated to when turntable 1016 rotates plus Sample Dilution mixes station 1013, sample is added to positioned at the station Reaction in-line dilution and mix.

It further include for extracting reagent from reagent storage unit 1008 and being put in reagent in reaction tube and rotatable lifting Reagent needle portion 1010；For extracting sample from sample storage unit and being put in sample in reaction tube and the specimen needle of rotatable lifting Portion 1011；For extracting the ultrasonic needle portion 1007 of magnetic bead reagent and rotatable lifting from reagent storage unit 1008；Specimen needle portion 1011, reagent needle portion 1010 and ultrasonic needle portion 1007 are close to reagent sample device 1018 and outer are set from upper to inner arc-shaped arrangement It sets.

Specimen needle portion 1011 is arranged between the first turntable 1016 and reagent sample device 1018, and reagent needle portion 1010 is set It sets between the first turntable 1016 and sampling clamp portion 1001, ultrasonic needle portion 1007 is arranged in the second turntable 1017 and reagent Between sample device 1018.

Reagent needle portion 1010, specimen needle portion 1011 and ultrasonic needle portion 1007 are the prior art in the utility model, such as existing Have in technology that application No. is a kind of liquid-transfering devices of band ultrasound of CN201720892947.7 to correspond to ultrasonic needle portion 1007, application number Correspond to reagent needle portion 1010 and specimen needle portion 1011 for a kind of technical solution for puncturing sampler of CN201220107100.0.

It further include the detection grip 1002 of liftable rotation, sample incubation detection device includes being incubated for disk 5 and cleaning disk 1, it is incubated for 5 concentric circles of disk and the inside of cleaning disk 1 is set and is relatively rotatable to each other, sampling clamp portion 1001 is by reaction tube from second It is grabbed on the interaction station 1003 of turntable 1017 and is incubated for disk 5, detection grip 1002 is used to grab the reaction tube for being incubated for disk 5 Cleaning disk 1 is got, the detection grip 1002 is positioned close to the second turntable 1017 simultaneously close to sample incubation detection dress Set place.In the above process, sampling clamp portion 1001, which grabs reaction tube, to be incubated on the arc line type interaction station of disk 5, and detection is grabbed Hand 1002 is also to grab on cleaning disk 1 from the reaction tube on the arc line shaped interaction station for being incubated for disk 5.

To further increase detection speed, reaction tube can also be placed on the first turntable 1016 by mechanically actuated On, i.e., in the feeding device 1015 that blank reaction tube is placed on to the first turntable 1016, feeding device is positioned close to first At turntable 1016.Feeding device can choose the structure of the prior art.

In the utility model sample reagent device 1018 in the specific implementation, in order to preferably realize the position to reaction tube Set, cast and type etc. are identified, sample reagent device 1018 is additionally provided with judgement system, and judgement system includes processor, pipe Type discriminating gear, specimen discerning device, reagent identification device and reaction tube positioning device；Processor differentiates with cast respectively to be filled It sets, specimen discerning device, reagent identification device are connected with reaction tube positioning device；Processor is also with setting in sample reagent device Outer ultrasonic needle portion 1007 connection.

Cast discriminating gear includes being respectively arranged on the sample reagent disk outer body of sample reagent device 1018 and close to sample The first reflective photoelectric sensor, the second reflective photoelectric sensor and the third reflection of this storage unit upper, middle and lower Formula photoelectric sensor；First reflective photoelectric sensor, the second reflective photoelectric sensor and third reflecting light fax Sensor is connect with processor respectively, is handled by the analysis of the signal feedback and processor of different reflective photoelectric sensors, The height of judgement sample pipe, to realize the automatic identification to the cast of different sample cells.

In order to preferably cool down to sample reagent device 1018, the utility model is the outfit of sample reagent device 1018 Water-cooling circulating system, water-cooling circulating system include refrigeration machine, cooling device and several Peltier；It is controlled and is made by processor The cryogenic temperature of cold, Peltier are connected with refrigeration machine, and the chill surface of all Peltier is attached to inner ring reagent storage unit bottom The heating position in portion, so that the purpose of cooling is played, the excessively high influence of the temperature of Peltier in order to prevent, the efficiency of cooling, Paar On the heating face of note, i.e., cooling device is arranged in the one side on ground in Peltier, sponges the heat in the heating face of Peltier To make Peltier in preferable working condition, guarantee cooling efficiency；Cooling device can be cooling coil(ed) pipe, cooling coil(ed) pipe It is connected with refrigeration machine.

Sample storage unit 1009 is reagent storage unit 1008 is outer and the circle distribution of 1008 concentric circles of reagent storage unit, reagent Reagent position circumferentially uniformly distributed is equipped with kit card slot in storage unit 1008, and each kit card slot is equipped with before and after kit Card slot and kit pre-tightening mechanism.

For being caught in kit card slot for kit energy fast reliable, setting is matched with reagent position on kit card slot Card slot and pre-tightening mechanism before and after the kit used；Pre-tightening mechanism can be the fastener being used cooperatively with reagent position；Pretightening machine Structure may be other structures fixed in advance convenient for kit.

In the utility model effect of the sample incubation detection device in luminescent chemical immunity analysis instrument be exactly to enter its In added with reagent sample reaction tube carry out immunoassay monitoring, have many devices in the prior art, as long as its incubation The interaction station for reaction tube interaction is provided on disk 5.

Specific embodiment can be with but not limited to this: as seen in figures 3-6, including rack, disk-like structure and rack-like structure.

As shown in Figure 3, Figure 4, rack includes two pieces of mounting plates 31, and reinforcement connection is provided between two pieces of mounting plates 31 Part 50.Two support columns 30 are provided on each piece of mounting plate 31, pedestal mounting plate 35 is set to 30 top of support column.

Wherein, disk-like structure is set in rack by a pedestal mounting plate 35.It includes being set to pedestal mounting plate 35 On cleaning external disk 2, be mounted on by support component on pedestal mounting plate 35 and be located at clear in cleaning the surrounded space of external disk 2 Dishwashing 1, is set to bottom at the incubation disk 5 for being set on pedestal mounting plate 35 by first driving device and being located at 1 inside of cleaning disk On seat mounting plate 35 and with the second driving device for being connected of cleaning disk 1 and it is set to the cover board 51 of cleaning 2 upper end of external disk.

Test tube hole location 52 is provided on cleaning disk 1 and incubation disk 5；Inlet pipe mouth 27, outlet pipe are provided on cover board 51 Mouth 28 is incubated for crawl mouth 29, filling opening 53 and liquid sucting port 54.Being incubated for corresponding position under crawl mouth 29 is to be incubated for disk interaction Position.

And the operation being made of sensor 10 and the code-disc 3 being set on cleaning disk 1 is also equipped in disk-like structure Timeslice detection device, as shown in Figure 4.

In addition, being provided with photon counter 6 in cleaning external disk 2.It is provided with and photon meter being incubated in cleaning disk device The Light source correction mounting base 37 that number device 6 is connected.And barn door 36 is provided with above Light source correction mounting base 37.

Support component includes 1 resilient support bearing 8 and 2 spring bearing 7；Resilient support bearing 8 and spring bearing 7 are set It is placed on pedestal mounting plate 35.

The incubation disk synchronous belt drive that first driving device includes the first driving motor 91, is connected with the first driving motor 91 Driving wheel 40, the incubation disk synchronous belt driven wheel 42 and incubation disk being connected with incubation disk synchronous belt driving wheel 40 by transmission belt The main shaft that synchronous belt driven wheel 42 is connected and the first encoder being set on main shaft.Main shaft passes through pedestal mounting plate 35 and incubates It educates disk 5 to be connected, be set on main shaft so that being incubated for disk 5.

Second driving device includes the second driving motor 92, the cleaning disk synchronous pulley being connected with the second driving motor 92 39, with cleaning disk synchronous pulley 39 be connected by transmission belt cleaning disk synchronous belt driven wheel 41, with cleaning disk synchronous belt from The drive shaft that driving wheel 41 is connected and the second encoder being set in drive shaft.One end of drive shaft passes through pedestal mounting plate 35 And it is connected by a driving gear 4 with cleaning disk 1.

The heat insulation foam 38 that a circle is fixed on pedestal mounting plate 35 is provided with being incubated for 5 lateral location of disk.And heat-insulated Heating film 33 is provided on the bottom surface of cotton 38, the bottom surface of pedestal mounting plate 35, cleaning 2 lateral surface of external disk and incubation disk 5.

It is additionally provided with magnet mounting hole on cleaning 2 lateral wall of external disk, outer ring magnet 34 is provided in magnet mounting hole. It is provided with magnet mounting base on cleaning 2 inner sidewall of external disk, inner ring magnet is provided in magnet mounting base.

As shown in Fig. 4, Fig. 5, Fig. 6, Fig. 7, rack-like structure setting is in rack comprising adding above disk-like structure Liquid mechanism, liquid sucting mechanism and grasping mechanism.

Grasping mechanism includes the handgrip fixing seat 18 being set on pedestal mounting plate 35, by the company of linear bearing guiding group 21 It connects in the push plate 22 in handgrip fixing seat 18, the push plate motor that is set in push plate 22 and is connected with linear bearing guiding group 21 44 and 3 handgrip seat shells 45 being set in handgrip fixing seat 18.

Handgrip 46 is provided in each handgrip seat shell 45.Each 45 upper end of handgrip seat shell is provided with driven synchronization 24,3 driven synchronous pulleys 24 of belt wheel are connect by synchronous belt with active synchronization belt wheel 26 respectively, active synchronization belt wheel 26 and rotation Turn driving motor 25 to be connected.Mandril 47 is connected on driven synchronous pulley 24, mandril 47 is connected with handgrip 46.

Liquid-adding device includes the first liquid feeding pin 11, the second liquid feeding pin being arranged in handgrip fixing seat 18 along clockwise direction Fixing seat 191, third liquid feeding pin fixing seat 192 and the 4th liquid feeding pin fixing seat 193.

In the second liquid feeding pin fixing seat 191, third liquid feeding pin fixing seat 192 and the 4th liquid feeding pin fixing seat 193 respectively It is provided with the second liquid feeding pin 12, third liquid feeding pin 13 and substrate liquid feeding pin 14.

Correspond to filling opening below first liquid feeding pin 11, the second liquid feeding pin 12, third liquid feeding pin 13 and substrate liquid feeding pin 14 53 and cleaning disk 1 on corresponding test tube hole location 52.

Liquid absorption device includes third driving motor and the aspirating needle mounting plate 23 being connected with third driving motor.

It is disposed with the first aspirating needle 15, the second aspirating needle 16 and along clockwise direction on aspirating needle mounting plate 23 Three aspirating needles 17.

And the first aspirating needle 15, the second aspirating needle 16 and third aspirating needle 17 add with the second liquid feeding pin 12, third respectively The previous test tube hole location 52 of liquid needle 13 and substrate liquid feeding pin 14 is corresponding.

The sample incubation detection system working principle of the utility model is as follows:

Cleaning external disk 2 is fixed on pedestal mounting plate 35, and 2 spring bearings 7 and 1 are equipped on pedestal mounting plate 35 Bearing 8 is flexibly supported, cleaning disk 1 is placed on spring bearing, drives driving gear 4 to rotate by the second driving motor 92, clearly It is fixed with code-disc 3 in dishwashing 1, runing time piece is detected by sensor 10.It is mounted with the reaction tube of reagent and sample, from inlet pipe Mouth 27 is placed into cleaning disk 1, and cleaning disk 1 is driven by cleaning disk synchronous pulley 39, will be mounted with reagent according to regular time piece Corresponding position is sent to the reaction tube of sample.

First liquid feeding pin 11 is installed in handgrip fixing seat 18, in addition there is the peace of 3 liquid feeding pin fixing seats 191,192,193 In handgrip fixing seat 18, the second liquid feeding pin 12 and third liquid feeding pin are fixed in the first two liquid feeding pin fixing seat 191,192 13, it is fixed with substrate liquid feeding pin 14 in third liquid feeding pin fixing seat 193, all corresponds to cleaning disk below all liquid feeding pins 1 corresponding test tube hole location 52.Second liquid feeding pin 12, third liquid feeding pin 13 and the corresponding cleaning disk 1 of substrate liquid feeding pin 14 are previous Hole location, respectively corresponds the first aspirating needle 15, the second aspirating needle 16 and third aspirating needle 17, and three aspirating needles are fixed on imbibition It is driven and is moved up and down by third driving motor on needle mounting plate 23.

Push plate 22 is connected in handgrip fixing seat 18 by linear bearing guiding group 21, drives straight line by push plate motor 44 Bearing guiding group 21 moves up and down.Handgrip fixing seat 18 is fixed with 3 handgrip seat shells 45, and 45 upper end of handgrip seat shell is equipped with 24,3 driven synchronous pulleys 24 of driven synchronous pulley are connect by synchronous belt with active synchronization belt wheel 26, by rotary drive motor 25 drivings, mandril 47 are passed through from driven synchronous pulley 24 and are protruded into handgrip 46, and handgrip 46 is fixed in handgrip seat shell 45, is grabbed The reaction tube picked up by handgrip 46 is pushed into cleaning 1 corresponding hole site of disk by push plate 22 by hand seat shell 45, mandril 47.

It cleans in 1 operation process of disk, in corresponding hole location to reaction tube therein is loaded in, carries out cleaning mixing.

After through outlet spout 28, reaction tube and the reaction tube reactant therein being loaded will enter incubation state, It completes to be incubated for by a regular time section, and is incubated for the reaction tube completed in the corresponding hole location detecting of photon counter 6.

It is provided with magnet mounting hole in cleaning external disk 2, inside is equipped with outer ring magnet 34, the magnetic with cleaning 1 inner ring of disk installation The inner ring magnet interaction installed in iron mounting base, increases the cleaning effect of the system.

Disk 5 is incubated for be connected on pedestal mounting plate 35 by main shaft, main shaft, which is connected to, to be incubated on disk synchronous belt driven wheel 42, It makes a circle within disk 5 weeks and heat insulation foam 38 is installed by being incubated for disk synchronous belt driving wheel 40 and the driving of the first driving motor 91, incubation, every Hot cotton 38 is mounted on pedestal mounting plate 35.The bottom surface of heat insulation foam 38, the bottom surface and cleaning 2 outer ring of external disk of pedestal mounting plate 35 are all Be provided with heating film 33 to whole system carry out temperature control, institute it is in need participate in be incubated for reaction tube from be incubated for crawl mouth 29 lead to External grasping mechanism is crossed to be grabbed.

Above-described specific embodiment, to the purpose of this utility model, technical scheme and beneficial effects carried out into One step is described in detail, it should be understood that being not used to limit the foregoing is merely specific embodiment of the present utility model Determine the protection scope of the utility model, within the spirit and principle of the utility model, any modification for being made equally is replaced It changes, improve, should be included within the scope of protection of this utility model.

Claims (7)

1. a kind of luminescent chemical immunity analysis instrument, which is characterized in that including sample incubation detection device, reagent sample device (1018), rotatable first transfer is provided between reagent sample device (1018) and sample incubation detection device from top to bottom Disk (1016), the sampling clamp portion (1001) of liftable rotation and rotatable second turntable (1017), the first turntable (1016) for the reaction tube transfer campaign after the completion of carrying out sample-adding originally, the second turntable (1017) is for carrying out reagent adding and magnetic Reaction tube transfer campaign after pearl is provided with crawl station (1012), the second turntable (1017) on the first turntable (1016) On be provided with interactive station (1003)；The rotatable spy of handgrip in sampling clamp portion (1001), which is got, is located at crawl station (1012) Reaction tube is located at the reaction tube for interacting station (1003) and can will be transferred to sample incubation inspection added with the reaction tube of reagent sample It surveys in device, when implementation, when the reaction tube on the first turntable (1016) turns to crawl station (1012), sampling clamp portion (1001) reaction tube for being located at crawl station (1012) is transferred to the second turntable (1017) by handgrip, when the second turntable (1017) when the reaction tube on is located at interaction station (1003), which is grabbed into this incubation detection device and is incubated Educate detection.

2. luminescent chemical immunity analysis instrument according to claim 1, which is characterized in that the turntable of the first turntable (1016) Other three stations: sample waiting station are evenly arranged with also along its circumferential direction in addition to grabbing station (1012) on ontology (1014), plus Sample Dilution mixes station (1013)；Except the interaction station of setting in the turntable body of second turntable (1017) (1003) outside, other three stations: reagent needle liquid feeding station (1004), ultrasonic needle liquid feeding work are evenly arranged with also along its circumferential direction Position (1006), reagent mix station (1005)；It is corresponded on each station on first turntable (1016) and the second turntable (1017) Offer the hole for placing response pipe.

3. luminescent chemical immunity analysis instrument according to claim 1, which is characterized in that reagent sample device (1018) includes It is arranged in by the reagent storage unit (1008) and sample storage unit (1009) on different motor-driven different turntables, different turntables For concentric circles setting.

4. luminescent chemical immunity analysis instrument according to claim 3, which is characterized in that further include for from reagent storage unit (1008) it extracts reagent and is put in reagent in reaction tube and the reagent needle portion (1010) of rotatable lifting；For being stored from sample It extracts sample and is put in sample in reaction tube and the specimen needle portion (1011) of rotatable lifting in portion；For from reagent storage unit (1008) the ultrasonic needle portion (1007) of magnetic bead reagent and rotatable lifting is extracted；Specimen needle portion (1011), reagent needle portion (1010) The periphery for being close to reagent sample device (1018) with ultrasonic needle portion (1007) is arranged from top to bottom.

5. luminescent chemical immunity analysis instrument according to claim 4, which is characterized in that specimen needle portion (1011) setting is the Between one turntable (1016) and reagent sample device (1018), reagent needle portion (1010) setting in the first turntable (1016) and Between sampling clamp portion (1001), ultrasonic needle portion (1007) is arranged in the second turntable (1017) and reagent sample device (1018) Between.

6. luminescent chemical immunity analysis instrument according to claim 1-5, which is characterized in that further include liftable rotation The detection grip (1002) turned, sample incubation detection device include being incubated for disk (5) and cleaning disk (1), are incubated for disk (5) concentric circles Inside in cleaning disk (1) is set and is relatively rotatable to each other, sampling clamp portion (1001) are by reaction tube from the second turntable (1017) it is grabbed on interaction station (1003) and is incubated for disk (5), detection grip (1002) is used to be incubated for the reaction of disk (5) Pipe grabs cleaning disk (1), and the detection grip (1002) is positioned close to the second turntable (1017) simultaneously close to sample It is incubated at detection device.

7. luminescent chemical immunity analysis instrument according to claim 6, which is characterized in that be incubated on disk (5) disk body along its week To the incubation disk interaction position for being provided with arc line type, it is incubated on disk interaction position and its camber line trend is provided with multiple interaction locations.