CN208161617U - A kind of controllable microlayer model generating means - Google Patents
A kind of controllable microlayer model generating means Download PDFInfo
- Publication number
- CN208161617U CN208161617U CN201820500390.2U CN201820500390U CN208161617U CN 208161617 U CN208161617 U CN 208161617U CN 201820500390 U CN201820500390 U CN 201820500390U CN 208161617 U CN208161617 U CN 208161617U
- Authority
- CN
- China
- Prior art keywords
- pipeline
- microsyringe
- micro
- fluidic chip
- model
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Micromachines (AREA)
Abstract
The utility model discloses a kind of controllable microlayer model generating means.The first microsyringe in the utility model is connected by the dispersed phase import of dispersed phase pipeline and micro-fluidic chip, and the second microsyringe is connected by the continuous phase import of continuous phase pipeline and micro-fluidic chip；The outlet of micro-fluidic chip is connect by export pipeline with receiving flask；The mechanical vibrator that the pipeline can be made to generate vibration, the vibration frequency and amplitude-controllable of mechanical vibrator are provided on the dispersed phase pipeline；First microsyringe is driven by the first syringe pump, and the second microsyringe is driven by the second syringe pump.The utility model only passes through the amplitude and frequency of control external mechanical vibrator, can reach and generate different size microlayer models, while control the purpose of drop formation frequency, can also improve the frequency of microlayer model generation.
Description
Technical field
The utility model belongs to field of fluid machinery, is related to a kind of controllable microlayer model generating means.
Background technique
In recent years, microlayer model technology is obtained by it in the great influence of scientific research field and the special applications of engineering field
Extensive concern.Researchers propose many methods for forming approximate monodisperse microlayer model, such as water dripping tap, nozzle
Release, microflow control technique etc..In these techniques, drop microfluid is a kind of most common method, can be used for food
Transmitting, drug delivery, chemical reaction, health monitoring and some other field of bioanalysis.Generally speaking, there are three types of typical
Geometry equipment can be used for generating microlayer model：T shape pipeline, flow focusing pipeline and coaxial flow duct.Wherein flow focusing pipe
Road can be realized the formation of microlayer model sequence within the scope of wider volume.A kind of typical flow focusing microfluidic device such as Fig. 1 institute
Show, it includes three entrances, and intermediate entrance injects dispersed phase, and the entrance of two sides injects continuous phase.Two kinds of unmixing fluids
It meets and is in contact with each other in narrow pipeline, then fracture is decomposed to form microlayer model.
Since microlayer model applies the required particle size in different field different, so to flowing focus type micro-fluidic chip
Higher requirements are also raised for the microlayer model of generation controlled dimensions.It is controllable to generate size for flow focusing type micro-fluidic chip at present
Microlayer model method have it is following several：First is that by the channel geometry of the micro-fluidic chip changed, for generating different rulers
Very little microlayer model, by changing channel geometry, to machining accuracy, more stringent requirements are proposed, and cost can also be substantially improved；
Second is that various sizes of microlayer model is controlled by the viscosity and surface tension of two kinds of fluids of change, but for given fluid
Property, this method is difficult to control the microlayer model size generated, therefore limits its application；Third is that passing through accurate control of fluid
Pressure controls various sizes of microlayer model, and fluid needs elevated pressures in operation, therefore also limit this method in reality
Application in the process.All more or less technically there is certain limitation and difficult point in use in the above method, and if
As soon as flow focusing type micro-fluidic chip can be controlled by applying a stable mechanical disturbance in outer portion dephasing pipeline with this
The generation of microlayer model can largely solve the above problems.
Summary of the invention
The utility model vibrates the deficiencies in the prior art, provides a kind of controllable microlayer model generating means.
The utility model technical solution adopted for solving the technical problem is：
The utility model includes micro-fluidic chip, receiving flask, export pipeline, dispersed phase pipeline, mechanical vibrator, first micro-
Measure sample injector, the first syringe pump, the second microsyringe, the second syringe pump, continuous phase pipeline；First microsyringe is by dividing
The dispersed phase import of dephasing pipeline and micro-fluidic chip connects, and the second microsyringe passes through continuous phase pipeline and micro-fluidic chip
Continuous phase import connection；The outlet of micro-fluidic chip is connect by export pipeline with receiving flask；On the dispersed phase pipeline
It is provided with the mechanical vibrator that the pipeline can be made to generate vibration, the vibration frequency and amplitude-controllable of mechanical vibrator；Described
One microsyringe is driven by the first syringe pump, and the second microsyringe is driven by the second syringe pump.
Furtherly, the micro-fluidic chip is flow focusing type micro-fluidic chip.
The utility model compared with prior art, has an advantageous effect in that：
1, existing flow focusing type micro-fluidic chip generates the process of microlayer model, can only pass through the geometry of change microchannel
The passive generation size and frequency because usually controlling microlayer model such as viscosity of structure, Fluid pressure and fluid, and cannot be actively
Control the generation frequency and size of microlayer model.The utility model by outer portion dephasing fluid circuit apply an amplitude,
The controllable mechanical vibrator of frequency can active control microlayer model generation size and frequency, greatly improve the life of drop
Produce efficiency.
2, the reason of for flow focusing type micro-fluidic chip because of external fluid flow and viscosity, so that generating microlayer model
Jet model is generated in the process, causes the non-uniform influence of microlayer model generated, it can be by being applied in dispersed phase fluid pipeline
Jet model can be transformed into drip mode, to improve under certain frequency and amplitude condition by the mechanical vibrator added
The stability of drop formation, so that the microlayer model particle size generated is consistent, the monodispersity with height.
3, the utility model mechanical vibrator controllable by application one amplitude, frequency in dispersed phase fluid pipeline,
The generation of microlayer model in flow focusing type micro-fluidic chip is controlled by changing amplitude and the frequency of mechanical vibrator, so that micro-
The generating process of drop has many advantages, such as that high degree of monodispersity, high throughput and size are controllable, realizes the efficient of microlayer model production
Rate expands the scope of application of the technology to meet the requirement of different practical applications.
Detailed description of the invention
Fig. 1 is flow focusing type micro-fluidic chip schematic diagram；
Fig. 2 is the utility model structure diagram.
Specific embodiment
The utility model is described further below in conjunction with attached drawing.
The utility model include micro-fluidic chip 13, receiving flask 4, export pipeline 5, dispersed phase pipeline 6, mechanical vibrator 7,
First microsyringe 8, the first syringe pump 9, the second microsyringe 11, the second syringe pump 12, continuous phase pipeline 12；First is micro-
It measures sample injector to connect by the dispersed phase import 2 of dispersed phase pipeline and micro-fluidic chip, the second microsyringe passes through continuous phase
The continuous phase import 3 of pipeline and micro-fluidic chip connects；The outlet 1 of micro-fluidic chip is connect by export pipeline with receiving flask；
Be provided on the dispersed phase pipeline can make the pipeline generate vibration mechanical vibrator, the vibration frequency of mechanical vibrator and
Amplitude-controllable；First microsyringe is driven by the first syringe pump, and the second microsyringe is driven by the second syringe pump.
Furtherly, when the micro-fluidic generation microlayer model of flow focusing type, pass through what is applied in outer portion dephasing pipeline
Mechanical oscillation keep the amplitude of mechanical vibrator constant, increase the vibration frequency of vibrator, can accelerate the generation speed of microlayer model
Rate, and when the vibration frequency of vibrator be greater than microlayer model situation without friction under generation frequency when, the generating rate of drop with
The vibration frequency of vibrator is synchronous, can accelerate drop formation frequency；It keeps the frequency of mechanical vibrator certain, increases vibrator
Amplitude can control microlayer model generate size, and when drop formation state be jet model when, pass through vibrator
The increase of amplitude is so that jet model becomes drip mode, the stability and monodispersity that raising microlayer model generates.
The course of work of the utility model：Push microsyringe that two kinds of Immiscible fluids is made to flow into flowing by syringe pump
In focus type micro-fluidic chip, two kinds of unmixing fluids meet and are in contact with each other in narrow pipeline, and then fracture is decomposed
Form drop.Since fluid flows, microlayer model enters in receiving flask through export pipeline, this process continuously generates microlayer model.When opening
When dynamic mechanical vibrator, change the amplitude and frequency of mechanical vibrator, can accurately control the size of microlayer model generation.
Such as：When the frequency that flow focusing type micro-fluidic chip 13 generates microlayer model is 30Hz, by outer scattered
The mechanical oscillation applied in phase pipeline 6, keeping the amplitude of mechanical vibrator 7 is 2 ㎜, changes the vibration frequency of mechanical vibrator 7,
When vibration frequency is greater than 30Hz, is less than 2kHz, the generating rate of microlayer model can be accelerated, and drop formation rate and vibration at this time
Dynamic frequency is consistent.The frequency for keeping mechanical vibrator 7 is 60Hz, changes the amplitude of mechanical vibrator 7（0cm-10cm）It can
Control the size that microlayer model generates.And when it is jet model that microlayer model, which generates state, shaken by mechanical vibrator 7
The increase of width is so that jet model becomes drip mode, the stability and monodispersity that raising microlayer model generates.
The above is only the preferred embodiment of the utility model, not imposes any restrictions to the utility model, all
According to any simple modification to the above embodiments of the utility model technical spirit, change and equivalent structural changes, still
Belong in the protection scope of technical solutions of the utility model.
Claims (2)
1. a kind of controllable microlayer model generating means, it is characterised in that：Including micro-fluidic chip, receiving flask, export pipeline, dispersed phase
Pipeline, mechanical vibrator, the first microsyringe, the first syringe pump, the second microsyringe, the second syringe pump, continuous phase pipe
Road；
First microsyringe is connected by the dispersed phase import of dispersed phase pipeline and micro-fluidic chip, and the second microsyringe is logical
The continuous phase import for crossing continuous phase pipeline and micro-fluidic chip connects；The outlet of micro-fluidic chip passes through export pipeline and receiving flask
Connection；
The mechanical vibrator that the pipeline can be made to generate vibration, the vibration frequency of mechanical vibrator are provided on the dispersed phase pipeline
Rate and amplitude-controllable；
First microsyringe is driven by the first syringe pump, and the second microsyringe is driven by the second syringe pump.
2. a kind of controllable microlayer model generating means according to claim 1, it is characterised in that：The micro-fluidic chip is
Flow focusing type micro-fluidic chip.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820500390.2U CN208161617U (en) | 2018-04-10 | 2018-04-10 | A kind of controllable microlayer model generating means |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820500390.2U CN208161617U (en) | 2018-04-10 | 2018-04-10 | A kind of controllable microlayer model generating means |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208161617U true CN208161617U (en) | 2018-11-30 |
Family
ID=64372382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820500390.2U Active CN208161617U (en) | 2018-04-10 | 2018-04-10 | A kind of controllable microlayer model generating means |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208161617U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113907058A (en) * | 2021-09-08 | 2022-01-11 | 安徽农业大学 | Pesticide spraying device based on flow focusing and operation method thereof |
-
2018
- 2018-04-10 CN CN201820500390.2U patent/CN208161617U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113907058A (en) * | 2021-09-08 | 2022-01-11 | 安徽农业大学 | Pesticide spraying device based on flow focusing and operation method thereof |
| CN113907058B (en) * | 2021-09-08 | 2022-12-13 | 安徽农业大学 | Pesticide spraying device based on flow focusing and operation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104084247B (en) | Elastic wall surface micro-fluidic chip based on T-shaped micro-channel | |
| Zhu et al. | Passive and active droplet generation with microfluidics: a review | |
| CN110052298A (en) | A method of vibration pipeline control micro-fluidic chip generates microlayer model | |
| Chong et al. | Active droplet generation in microfluidics | |
| EP2411133B1 (en) | Droplet generator | |
| CN108499500A (en) | A method of vibration pipeline control flow focusing type micro-fluidic chip generates microlayer model | |
| Cubaud et al. | Folding of viscous threads in diverging microchannels | |
| CN109701430A (en) | A method of vibration pipeline control T-type micro-fluidic chip generates microbubble | |
| Xia et al. | Nonlinear microfluidics: device physics, functions, and applications | |
| Tarchichi et al. | New regime of droplet generation in a T-shape microfluidic junction | |
| CN105413772A (en) | Single/multiple-component droplet preparation device based on integrated micro-channels and control method of single/multiple-component droplet preparation device | |
| CN108525715B (en) | Micro-channel structure, micro-fluidic chip and method for quantitatively wrapping microspheres by liquid drops | |
| CN104888875A (en) | Lower wall specified position movable micro-fluidic chip based on microchannel | |
| Ong et al. | Experimental and computational analysis of droplet formation in a high-performance flow-focusing geometry | |
| Wang et al. | Microblower-based microfluidic pump | |
| CN104826674A (en) | Reverse-Y shaped channel microfluid chip for generating droplets | |
| Jin et al. | Visualization of droplet merging in microchannels using micro-PIV | |
| CN108993622B (en) | Micro-fluidic chip for realizing collision of different combined liquid drops | |
| Cheung et al. | Characterization of acoustic droplet formation in a microfluidic flow-focusing device | |
| Mu et al. | Instability analysis of the cone–jet flow in liquid-driven flow focusing | |
| Li et al. | Perturbation-induced droplets for manipulating droplet structure and configuration in microfluidics | |
| CN208161617U (en) | A kind of controllable microlayer model generating means | |
| Liang et al. | Manipulable formation of ferrofluid droplets in Y-shaped flow-focusing microchannels | |
| Wang et al. | Droplet generation in micro-sieve dispersion device | |
| Wang et al. | A new bubble-driven pulse pressure actuator for micromixing enhancement |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |