CN206292243U - For the micro-fluidic chip of Blood grouping - Google Patents
For the micro-fluidic chip of Blood grouping Download PDFInfo
- Publication number
- CN206292243U CN206292243U CN201621385072.3U CN201621385072U CN206292243U CN 206292243 U CN206292243 U CN 206292243U CN 201621385072 U CN201621385072 U CN 201621385072U CN 206292243 U CN206292243 U CN 206292243U
- Authority
- CN
- China
- Prior art keywords
- cavity
- micro
- fluidic chip
- blood
- blood grouping
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
This case is related to a kind of micro-fluidic chip for Blood grouping, includes the microfluidic elements that disk and several uniform intervals are distributed on the disk；Opening is provided with the axle center of disk, edge of opening is provided with limiting section；Microfluidic elements include sample-adding cavity, waste liquid cavity, multiple quantitative cavity and test chamber corresponding with each quantitative cavity；Adding mouth is provided with sample-adding cavity；Throttling runner is provided between sample-adding cavity and quantitative cavity；It is quantitative that centrifugation micro-valve is provided between cavity and test chamber；Decimated streams road is provided between quantitative cavity and quantitative cavity；Waste liquid cavity is also associated with grate flow channel, and exhaust outlet is provided with grate flow channel.This case improves the detection flux of Blood grouping by the improvement to microfluidic chip structure, simplifies detection operation so that assay can trace to the source, while also improving accuracy of detection and detection efficiency.
Description
Technical field
The utility model is related to a kind of micro-fluidic chip, more particularly to a kind of micro-fluidic chip for Blood grouping.
Background technology
Micro-fluidic chip is current micro-total analysis system (Micro Total Analysis Systems, μ-TAS) development
Hot fields, it be with chip as carrier, and by and the technology such as biology, chemistry, drug screening combination, completion includes trying
The technology in interior whole process such as agent loading, separation, reaction, detection.In recent years, with the fast development of biochip technology,
Micro-fluidic chip plays more and more important effect in life science, analytical chemistry and biomedical sector.
Blood transfusion compatibility detection is to ensure that the necessary condition of clinic blood transfusion safety, and predominantly detecting content includes three parts：
The typing of blood, antibody calibrating, cross matching；According to infusion composition difference, can also be divided into erythrocyte blood type compatibility test and
Blood group of thrombocyte compatibility test.The typing of blood is to ensure that blood donor is consistent with the blood group of receptor, the red blood cell or blood of infusion
Platelet does not make receptor produce corresponding immune antiboidy；It is to detect the red blood cell for not existing and being input into receptor's serum that antibody is examined and determine
Or the corresponding specific antibody of platelet antigen；Cross matching be then directly observation receptor's serum in whether there is and infusion
With the presence or absence of small with receptor's red blood cell or blood in red blood cell or the corresponding specific antibody of blood platelet, and the blood plasma of input
The corresponding specific antibody of plate.These specific antibodies are typically all to refer to the blood group antibody for having clinical meaning, including are resisted completely
Body and incomplete antibody, it may be said that blood transfusion compatibility test is exactly mainly by blood group serology technology and related reagent group
Into.
By taking erythrocyte blood type calibrating as an example, the erythrocyte blood type for determining receptor and blood donor is checked, it is topmost to be exactly
Abo blood group and RhD blood groups are judged, because their groups compatible is maximum to safe transfusion clinical meaning.People's abo blood group be by
ABO antibodies in its red cell antigens and blood are determined that conventional calibrating is by agglutination test：Checked with anti-A and anti-B
Red cell antigens to be measured, referred to as positive definite form；The antibody in test serum, referred to as reverse type are checked with A types and Type B red blood cell, it is strong
Positive reverse type is consistent health people under normal circumstances.Have only neonate within birth 4-6 months due to blood in ABO antibodies activity too
It is weak and containing the antibody from mother, therefore neonate's blood group can only examine and determine its abo blood group with positive definite form method.Compared to it
Under, people RhD blood groups generally only detect D antigens, i.e., check red cell antigens to be measured with anti-D.It should be noted that because RhD is anti-
Former multi-epitope property, its occurrence frequency and expression in Caucasia crowd and Chinese population have very big difference, it is necessary to
Using different blood typing scheme and different antibody reagents.
Abo blood group calibrating is detected at end of donating blood to the blood group of large quantities of blood donors, general to use paper card method and microwell plate
Method, paper card method is manual operations, and Microdilution plate method is adapted to automation mechanized operation.The abo blood group calibrating side to blood donor of developed country
Method mainly uses high flux, the Microdilution plate method of automation；The country is two methods and deposits that paper card method is in blood-collecting car or outlying base
Layer place still widely uses, and it has the disadvantage manual operation, less efficient, artificial sentence read result, is disturbed more by extraneous factor, this
Outer testing result cannot trace to the source.On the other hand before blood transfusion, such as hospital is also needed to that abo blood group is carried out to check inspection with blood mechanism
Survey, it is necessary to using more reliable detection methods such as test tube method or micro-column gel agglutination assay.Test tube method is artificial operation, and step is more numerous
It is trivial, it is necessary to the multiple process such as washing, although it is more accurate than paper card method, but its defect is also similar with paper card method；Micro-column gel agglutination assay
Can automation mechanized operation, but treat that mark sheet, reagent quality and instrument requirements are very high and relatively costly, both approaches are current
At home and abroad there is use in clinical practice.For the RhD typings of blood, because its agglutinating reaction is not so good as the strong of ABO, and during reaction
Between it is slightly longer, therefore developed country do not advocate with paper card method or slide method, it is recommended to use test tube method, Microdilution plate method and micro-column gel
Method；And many places of China are also detected in application slide method.
Microwell plate solid agglutination is tested and micro-column gel immuno analytical method is all to start appearance the nineties in last century, is based on
They develop widely used Microdilution plate method and micro-column gel agglutination assay in current automation mechanized operation.Microdilution plate method is public with Immucor
The Capture R technologies of department are most well-known, and the country there is no similar product.Micro-column gel agglutination assay is earliest Switzerland's DiaMed (DiaMed)
Patent, after purchased by Bio-Rad, the rich news in the country earliest domesticize micro-column gel for 1996, the blood based on micro-column gel agglutination assay
Type detection reagent card is widely used abroad, and the country also has and largely uses, but its continuous elevated cost limits examination
Agent is stuck in the popularization in domestic and developing country market, and its range of application also has limitation.Microdilution plate method and micro-column gel agglutination assay essence
On be all immune agglutinate test, each there is fixed purposes and status, vie each other, will not be complete in a very long time
Substitution, is limited to the cost of its reagent and instrument, domestic and developing country market and clinic need badly one kind can replace paper card method and
Slide method, while cost is less than Microdilution plate method and the new product of micro-column gel agglutination assay.
Utility model content
In view of the shortcomings of the prior art, this case provides a kind of micro-fluidic chip for Blood grouping.For glass
Piece method and test tube method sensitiveness are poor, result judges to rely on manually, it is necessary to experience higher, operation are difficult to standardize and assay
The problems such as preserving and trace to the source for a long time is difficult to, this case exploitation uses micro-fluidic chip as the ABO/RhDE Blood grouping systems of carrier
Solution, it is final to realize improving detection flux, simplify operation, assay can trace to the source, and improve the mesh of accuracy of detection and efficiency
's.
To achieve the above object, this case is achieved through the following technical solutions：
A kind of micro-fluidic chip for Blood grouping, it includes disk and several uniform intervals are distributed in the disk
On microfluidic elements；Wherein, the opening for being fixed on centrifuge is provided with the axle center of the disk, the edge of opening sets
Limited location portion；
The microfluidic elements include sample-adding cavity, waste liquid cavity, multiple quantitative cavity and quantitative with each described
The one-to-one test chamber of cavity；Adding mouth is provided with the sample-adding cavity；The sample-adding cavity and the quantitative cavity it
Between be provided with throttling runner；Described quantifying is provided with centrifugation micro-valve between cavity and the test chamber；The quantitative cavity with
Decimated streams road is provided between quantitative cavity；The waste liquid cavity is also associated with grate flow channel, is provided with the grate flow channel
Exhaust outlet.
Preferably, the described micro-fluidic chip for Blood grouping, wherein, a diameter of 0.7- of the adding mouth
1.3mm。
Preferably, the described micro-fluidic chip for Blood grouping, wherein, the volume of the sample-adding cavity is 50-
150μL。
Preferably, the described micro-fluidic chip for Blood grouping, wherein, the depth of the throttling runner is 0.4-
0.8mm, width is 0.5-1.3mm.
Preferably, the described micro-fluidic chip for Blood grouping, wherein, the volume of the quantitative cavity is 10-
30μL。
Preferably, the described micro-fluidic chip for Blood grouping, wherein, the depth of the centrifugation micro-valve is 0.4-
0.8mm, width is 0.1-0.3mm.
Preferably, the described micro-fluidic chip for Blood grouping, wherein, a diameter of 3- of the test chamber
5mm, depth is 0.4-0.8mm.
Preferably, the described micro-fluidic chip for Blood grouping, wherein, the volume of the waste liquid cavity is 20-
50μL。
Preferably, the described micro-fluidic chip for Blood grouping, wherein, a diameter of 0.7- of the exhaust outlet
1.3mm。
The beneficial effects of the utility model are：This case improves Blood grouping by the improvement to microfluidic chip structure
Detection flux, simplify detection operation so that assay can trace to the source, while also improving accuracy of detection and detection efficiency.
Brief description of the drawings
Fig. 1 is the structural representation of the micro-fluidic chip for Blood grouping.
Fig. 2 is the enlarged drawing of microfluidic elements.
Specific embodiment
The utility model is described in further detail below in conjunction with the accompanying drawings, to make those skilled in the art with reference to explanation
Book word can be implemented according to this.
As depicted in figs. 1 and 2, the micro-fluidic chip for Blood grouping of an embodiment is listed in this case, and it includes circle
Disk 1 and several uniform intervals are distributed in the microfluidic elements 2 on the disk 1；Wherein, it is provided with the axle center of disk 1 for solid
Due to the opening 3 of centrifuge, 3 edges of opening are provided with limiting section 4；
Microfluidic elements 2 include sample-adding cavity 201, waste liquid cavity 202, multiple quantitative cavitys 203 and determine with each
The amount one-to-one test chamber 204 of cavity 203；Adding mouth 205 is provided with sample-adding cavity 201；Sample-adding cavity 201 and quantitative chamber
Throttling runner 206 is provided between body 203；It is quantitative that centrifugation micro-valve 207 is provided between cavity 203 and test chamber 204；It is quantitative
Decimated streams road 208 is provided between cavity 203 and quantitative cavity 203；Waste liquid cavity 202 is also associated with grate flow channel 209, exhaust
Exhaust outlet 210 is provided with runner 209.
Wherein, the diameter of adding mouth 205 is preferably 0.7-1.3mm.
Wherein, the volume of sample-adding cavity 201 is preferably 50-150 μ L.
Wherein, the depth of throttling runner 206 is preferably 0.4-0.8mm, and width is preferably 0.5-1.3mm.
Wherein, the volume of quantitative cavity 203 is preferably 10-30 μ L.
Wherein, centrifugation micro-valve 207 is throttle-type runner, and its depth is preferably 0.4-0.8mm, and width is preferably 0.1-
0.3mm。
Wherein, test chamber 204 is generally collar plate shape, and its diameter is preferably 3-5mm, and depth is preferably 0.4-0.8mm.
Wherein, the volume of waste liquid cavity 202 is preferably 20-50 μ L.
Wherein, the diameter of exhaust outlet 210 is preferably 0.7-1.3mm.
This case micro-fluidic chip is applied in the equipment of achievable centrifugal rotation, and stream is manipulated using centrifugal force, capillary force
The motion of body, and using centrifugal process twice, sample is centrifuged to quantitative cavity 203, test chamber successively from sample-adding cavity 201
Body 204, and the mixing of the quantitative and reagent of sample is realized in this whole process and receives optics in test chamber 204
Detection.Its detailed process can be described as：
1) sample is added to sample-adding cavity 201 by adding mouth 205；
2) low-speed centrifugal, rotating speed 20-600rpm, time 15-30s, sample under the action of the centrifugal force, through throttling runner
206th, successively full of quantitative cavity 203 behind decimated streams road 208.Unnecessary sample will flow into waste liquid cavity 202.
3) it is centrifuged again, rotating speed is improved to 900-1500rpm, time 5s, the sample in quantitative cavity 203 is in centrifugation masterpiece
With the lower resistance that will be overcome and micro-valve 207 is centrifuged, into test chamber 204.And mix with reagent in test chamber 204.
4) reciprocating concussion centrifugation, rotating speed 80-150rpm clockwise, time 3-5s, rotating speed 80-150rpm counterclockwise, when
Between 3-5s；Circulation 8-20 times.Now sample will fully react in the presence of earthquake power with reagent；
5) test chamber 204 receives external optical detection devices detection.
The micro-fluidic chip of this case is disposable, and using i.e. discardable after complete, its material is preferably PMMA, chip diameter
Generally 60-100mm, thickness is generally 1-2mm, is disposably machined using precision milling machine.Examination in test chamber 204
During agent can in advance deposit in test chamber 204 for lyophilized form or air-dried form.
Although embodiment of the present utility model is disclosed as above, it is not restricted in specification and implementation method
Listed utilization, it can be applied to various suitable fields of the present utility model completely, for those skilled in the art,
Other modification is easily achieved, therefore under the universal limited without departing substantially from claim and equivalency range, this reality
Specific details is not limited to new and shown here as the legend with description.
Claims (9)
1. a kind of micro-fluidic chip for Blood grouping, it is characterised in that include disk and several uniform intervals are distributed
Microfluidic elements on the disk；Wherein, the opening for being fixed on centrifuge is provided with the axle center of the disk, it is described to open
Mouth edge is provided with limiting section；
The microfluidic elements include sample-adding cavity, waste liquid cavity, multiple quantitative cavity and with quantitative cavity each described
One-to-one test chamber；Adding mouth is provided with the sample-adding cavity；Set between the sample-adding cavity and the quantitative cavity
It is equipped with throttling runner；Described quantifying is provided with centrifugation micro-valve between cavity and the test chamber；It is described to quantify cavity and quantify
Decimated streams road is provided between cavity；The waste liquid cavity is also associated with grate flow channel, and exhaust is provided with the grate flow channel
Mouthful.
2. the as claimed in claim 1 micro-fluidic chip for being used for Blood grouping, it is characterised in that the adding mouth it is a diameter of
0.7-1.3mm。
3. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the volume of the sample-adding cavity
It is 50-150 μ L.
4. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the depth of the throttling runner
It is 0.4-0.8mm, width is 0.5-1.3mm.
5. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the volume of the quantitative cavity
It is 10-30 μ L.
6. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the depth of the centrifugation micro-valve
It is 0.4-0.8mm, width is 0.1-0.3mm.
7. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the diameter of the test chamber
It is 3-5mm, depth is 0.4-0.8mm.
8. the micro-fluidic chip of Blood grouping is used for as claimed in claim 1, it is characterised in that the volume of the waste liquid cavity
It is 20-50 μ L.
9. the as claimed in claim 1 micro-fluidic chip for being used for Blood grouping, it is characterised in that the exhaust outlet it is a diameter of
0.7-1.3mm。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621385072.3U CN206292243U (en) | 2016-12-16 | 2016-12-16 | For the micro-fluidic chip of Blood grouping |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621385072.3U CN206292243U (en) | 2016-12-16 | 2016-12-16 | For the micro-fluidic chip of Blood grouping |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206292243U true CN206292243U (en) | 2017-06-30 |
Family
ID=59104692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621385072.3U Active CN206292243U (en) | 2016-12-16 | 2016-12-16 | For the micro-fluidic chip of Blood grouping |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206292243U (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247150A (en) * | 2017-08-14 | 2017-10-13 | 河北工业大学 | Blood group detection device based on micro-fluidic chip and STM32 |
| CN109954524A (en) * | 2019-03-22 | 2019-07-02 | 南京航思生物科技有限公司 | A kind of micro-fluidic chip to be shone based on homogeneous chemistry |
| CN110082526A (en) * | 2019-05-20 | 2019-08-02 | 中国科学院苏州生物医学工程技术研究所 | The exclusion chromatography new detecting method of immune complex |
| TWI685651B (en) * | 2017-12-12 | 2020-02-21 | 國立成功大學 | Micro fluid chip |
| WO2020192168A1 (en) * | 2019-03-27 | 2020-10-01 | 广州万孚生物技术股份有限公司 | Microfluidic chip and in vitro testing device containing the microfluidic chip |
| CN112500999A (en) * | 2019-09-16 | 2021-03-16 | 台达电子工业股份有限公司 | Biological detection cassette and operation method thereof |
| CN112871228A (en) * | 2021-01-11 | 2021-06-01 | 中国科学院苏州生物医学工程技术研究所 | Microfluidic detection device for blood type detection |
| CN113634295A (en) * | 2021-09-14 | 2021-11-12 | 南京岚煜生物科技有限公司 | Microfluidic blood type detection chip |
| WO2021243946A1 (en) * | 2020-06-04 | 2021-12-09 | 天津德祥生物技术有限公司 | Side-sample-adding micro-fluidic chip |
| WO2022048374A1 (en) * | 2020-09-07 | 2022-03-10 | 深圳市亚辉龙生物科技股份有限公司 | Droplet microfluidic chip and microdroplet preparation method |
| CN114324957A (en) * | 2022-03-16 | 2022-04-12 | 天津德祥生物技术有限公司 | Blood type positive and negative shaping sample adding card and sample adding assembly |
| CN114839179A (en) * | 2022-04-26 | 2022-08-02 | 华中农业大学 | Method for rapidly detecting organochlorine pesticide residues in plant matrix |
| CN115541895A (en) * | 2022-11-29 | 2022-12-30 | 天津德祥生物技术股份有限公司 | Formula liquid for improving sensitivity of micro-fluidic inverse detection card and application |
| CN116298347A (en) * | 2023-05-12 | 2023-06-23 | 北京未神生物科技有限公司 | Centrifugal microfluidic full-automatic blood type detection card and detection method thereof |
-
2016
- 2016-12-16 CN CN201621385072.3U patent/CN206292243U/en active Active
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247150B (en) * | 2017-08-14 | 2023-06-23 | 河北工业大学 | Blood group detection device based on micro-fluidic chip and STM32 |
| CN107247150A (en) * | 2017-08-14 | 2017-10-13 | 河北工业大学 | Blood group detection device based on micro-fluidic chip and STM32 |
| TWI685651B (en) * | 2017-12-12 | 2020-02-21 | 國立成功大學 | Micro fluid chip |
| CN109954524A (en) * | 2019-03-22 | 2019-07-02 | 南京航思生物科技有限公司 | A kind of micro-fluidic chip to be shone based on homogeneous chemistry |
| WO2020192168A1 (en) * | 2019-03-27 | 2020-10-01 | 广州万孚生物技术股份有限公司 | Microfluidic chip and in vitro testing device containing the microfluidic chip |
| CN110082526A (en) * | 2019-05-20 | 2019-08-02 | 中国科学院苏州生物医学工程技术研究所 | The exclusion chromatography new detecting method of immune complex |
| CN110082526B (en) * | 2019-05-20 | 2022-06-17 | 中国科学院苏州生物医学工程技术研究所 | New method for exclusion chromatography detection of immune complex |
| CN112500999A (en) * | 2019-09-16 | 2021-03-16 | 台达电子工业股份有限公司 | Biological detection cassette and operation method thereof |
| WO2021243946A1 (en) * | 2020-06-04 | 2021-12-09 | 天津德祥生物技术有限公司 | Side-sample-adding micro-fluidic chip |
| WO2022048374A1 (en) * | 2020-09-07 | 2022-03-10 | 深圳市亚辉龙生物科技股份有限公司 | Droplet microfluidic chip and microdroplet preparation method |
| EP4154980A4 (en) * | 2020-09-07 | 2024-06-26 | Shenzhen Yhlo Biotech Co., Ltd. | Droplet microfluidic chip and microdroplet preparation method |
| CN112871228A (en) * | 2021-01-11 | 2021-06-01 | 中国科学院苏州生物医学工程技术研究所 | Microfluidic detection device for blood type detection |
| CN113634295A (en) * | 2021-09-14 | 2021-11-12 | 南京岚煜生物科技有限公司 | Microfluidic blood type detection chip |
| JP7399518B2 (en) | 2021-09-14 | 2023-12-18 | 南京▲嵐▼▲ゆい▼生物科技有限公司 | Microfluidic control blood type detection chip |
| JP2023544659A (en) * | 2021-09-14 | 2023-10-25 | 南京▲嵐▼▲ゆい▼生物科技有限公司 | Microfluidic control blood type detection chip |
| CN114324957A (en) * | 2022-03-16 | 2022-04-12 | 天津德祥生物技术有限公司 | Blood type positive and negative shaping sample adding card and sample adding assembly |
| CN114324957B (en) * | 2022-03-16 | 2022-05-20 | 天津德祥生物技术有限公司 | Blood type positive and negative shaping sample adding card and sample adding assembly |
| CN114839179A (en) * | 2022-04-26 | 2022-08-02 | 华中农业大学 | Method for rapidly detecting organochlorine pesticide residues in plant matrix |
| CN115541895A (en) * | 2022-11-29 | 2022-12-30 | 天津德祥生物技术股份有限公司 | Formula liquid for improving sensitivity of micro-fluidic inverse detection card and application |
| CN116298347A (en) * | 2023-05-12 | 2023-06-23 | 北京未神生物科技有限公司 | Centrifugal microfluidic full-automatic blood type detection card and detection method thereof |
| CN116298347B (en) * | 2023-05-12 | 2023-07-25 | 北京未神生物科技有限公司 | Centrifugal microfluidic full-automatic blood type detection card and detection method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN206292243U (en) | For the micro-fluidic chip of Blood grouping | |
| CN105062866B (en) | For disposable separating chips module and the using method thereof of Peripheral Circulation tumour cell | |
| JP7399518B2 (en) | Microfluidic control blood type detection chip | |
| CN109212201A (en) | A kind of centrifugal type microfludic chip for hepatitis B five detections in serum | |
| CN103627638A (en) | Composition for lysing red cells, red cell lysing reagent and application of red cell lysing reagent | |
| US20070231834A1 (en) | Blood test kit | |
| CN108795693A (en) | A kind of micro-fluidic chip of capture blood rare cell | |
| Bhagwat et al. | Comparison between conventional and automated techniques for blood grouping and crossmatching: experience from a tertiary care centre | |
| CN203083997U (en) | ABO and RhD blood group antigen detection card | |
| US20240192109A1 (en) | Method for label-free cell activation profiling using microfluidic impedance cytometry | |
| Rey Gomez et al. | Emerging microfluidic devices for sample preparation of undiluted whole blood to enable the detection of biomarkers | |
| WO2020001662A1 (en) | Rare cell capture system and application thereof | |
| Su et al. | A low cost, membranes based serum separator modular | |
| CN109932234A (en) | A kind of micro-fluidic automatic cross matching system of whole blood and match method | |
| CN116493061B (en) | Blood detection micro-fluidic chip and detection method thereof | |
| JP6049493B2 (en) | Screening method for finding samples with antiphospholipid antibodies | |
| CN204939452U (en) | For the disposable separating chips module of Peripheral Circulation tumour cell | |
| CN212748953U (en) | Micro-fluidic reagent card | |
| Finck et al. | Performance of an automated solid-phase red cell adherence system compared with that of a manual gel microcolumn assay for the identification of antibodies eluted from red blood cells | |
| CN207866605U (en) | A kind of micro-fluidic automatic cross matching system of whole blood | |
| CN212134715U (en) | Integrated detection card for blood type and hemolytic disease of newborn | |
| CN203587414U (en) | Red blood cell pyrolysis kit for flow cytometry | |
| CN101221181B (en) | Indirect method for detecting lymphocyte subgroup with mono-clone antibody SPA hematid rosette method | |
| CN206740785U (en) | A kind of quantitative blood and haemocyte filtering sample-adding is used to detect syphilis antibody device | |
| Kharshandi et al. | A comparative study between gel card method and manual method for Coomb’s test |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |