CN204374070U - The apparatus for measuring concentration of high precision biomarker - Google Patents
The apparatus for measuring concentration of high precision biomarker Download PDFInfo
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- CN204374070U CN204374070U CN201520086599.5U CN201520086599U CN204374070U CN 204374070 U CN204374070 U CN 204374070U CN 201520086599 U CN201520086599 U CN 201520086599U CN 204374070 U CN204374070 U CN 204374070U
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- 239000000090 biomarker Substances 0.000 title claims abstract description 68
- 238000001228 spectrum Methods 0.000 claims abstract description 97
- 230000008859 change Effects 0.000 claims abstract description 14
- 239000000427 antigen Substances 0.000 claims abstract description 13
- 102000036639 antigens Human genes 0.000 claims abstract description 13
- 108091007433 antigens Proteins 0.000 claims abstract description 13
- 230000003595 spectral effect Effects 0.000 claims abstract description 8
- 239000003446 ligand Substances 0.000 claims description 34
- 238000006243 chemical reaction Methods 0.000 claims description 17
- 230000003321 amplification Effects 0.000 claims description 8
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 8
- 239000003638 chemical reducing agent Substances 0.000 claims description 2
- 238000005259 measurement Methods 0.000 abstract description 12
- 239000000463 material Substances 0.000 abstract description 4
- 230000002776 aggregation Effects 0.000 abstract description 2
- 238000004220 aggregation Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 6
- 230000006978 adaptation Effects 0.000 description 2
- 238000005842 biochemical reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 2
- 239000012491 analyte Substances 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 201000009310 astigmatism Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
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Abstract
The utility model discloses a kind of apparatus for measuring concentration of high precision biomarker, this device comprises: bio-sensing module, comprises light receiving unit and sensing unit; Light receiving unit is used for receiving and reflectance signature spectral signal, and sensing unit is in conjunction with the antigen in biomarker; Spectrum acquisition module, for receiving the characteristic spectrum signal of light receiving unit reflection, and is sent to control module by characteristic spectrum signal; Control module, for receive feature spectral signal, and controls driver module drive helical orbit resistance and spectrum acquisition block motion; And receive the output resistance of helical orbit resistance; Helical orbit resistance, moves to change output resistance under the driving of driver module; Concentration module, is arranged at the front end of spectrum acquisition module, for aggregation characteristic spectral signal.This programme avoids the type of biomarker itself and the impact of interference material, thus improves the degree of accuracy of the measurement of concetration to biomarker.
Description
Technical field
The utility model relates to life and health technical field, particularly relates to a kind of apparatus for measuring concentration of high precision biomarker.
Background technology
At present, the application of variohm widely, such as, can change the characteristic of signal generator, make lights dim, actuating motor or control its rotating speed etc.In precise hard_drawn tuhes and field of precision measurement, existing variohm is difficult to the demand meeting its precision, and the measurement of concentration for biomarker, usually the method adopted is photometric method, by in vitro the component of the humoral specimen of human body being mixed with one or more testing reagents, repeatedly determine the concentration of analyte, cause biochemical reaction thus, this makes the optical characteristics of measured object that the change that can survey occur, photometric method inspection and utilize light stream to pass light absorptive and/or the medium of astigmatism time the weakening of generation, but, this measuring method is owing to being subject to the type of sample itself and the impact of its interference material that may comprise, cause the easy generation systems mistake when measuring, make the measurement result of the concentration to biomarker not accurate enough.
Utility model content
Fundamental purpose of the present utility model is the apparatus for measuring concentration providing a kind of high precision biomarker, can improve the degree of accuracy of the measurement of concetration to biomarker.
For achieving the above object, the utility model provides a kind of apparatus for measuring concentration of high precision biomarker, and the apparatus for measuring concentration of described high precision biomarker comprises bio-sensing module, spectrum acquisition module, control module, driver module, helical orbit resistance and concentration module:
Described bio-sensing module comprises light receiving unit and sensing unit; Described light receiving unit is used for receiving and reflectance signature spectral signal, and described sensing unit is in conjunction with the antigen in biomarker;
Described spectrum acquisition module, is connected with described control module and driver module, for receiving the characteristic spectrum signal of described light receiving unit reflection, and described characteristic spectrum signal is sent to described control module;
Described control module, is electrically connected with described driver module, for receiving described characteristic spectrum signal, and controls described driver module and drives described helical orbit resistance and described spectrum acquisition block motion; And receive the output resistance of described helical orbit resistance;
Described helical orbit resistance, is electrically connected with described driver module, moves the output resistance changing described helical orbit resistance under the driving of described driver module;
Described concentration module, is arranged at the front end of described spectrum acquisition module, for assembling described characteristic spectrum signal.
Preferably, described sensing unit comprises the metallic diaphragm be arranged on described light receiving unit, and is arranged on the antibody layer on described metallic diaphragm, and this antibody layer is in conjunction with the antigen in biomarker.
Preferably, described helical orbit resistance comprises resistor main body, resistance ligand and resistive:
Described resistor main body surface is provided with the first screw thread; Described resistance ligand is set in described resistor main body, and described resistance ligand is provided with the second screw thread with described first threaded adapter; The first end of described resistive is fixed on described resistance ligand, the second end of described resistive and the surface contact of described first screw thread.
Preferably, described resistor main body is connected with described driver module, under the driving of described driver module, drive described resistance ligand to move, described resistance ligand drives described resistive to move along the surface of described first screw thread, to change the output resistance of described helical orbit resistance;
Described spectrum acquisition module is connected with described resistance ligand, and described resistor main body drives described resistance ligand to move under the driving of described driver module, to drive described spectrum acquisition block motion.
Preferably, the apparatus for measuring concentration of described high precision biomarker also comprises the slowdown module be connected with described driver module, the rotating speed that described slowdown module rotates for reducing described driver module.
Preferably, described slowdown module is first stage decelerator or multi-stage speed reducer.
Preferably, the apparatus for measuring concentration of described high precision biomarker also comprises signal processing module, the output terminal of described helical orbit resistance is electrically connected with the input end of described signal processing module, the output terminal of described signal processing module is electrically connected with described control module, and described signal processing module is used for carrying out signal conversion to described output resistance, signal amplifies and A/D conversion.
Preferably, described signal processing module comprises the resistive voltage signal conversion unit for being converted to voltage signal to described output resistance, the amplifying unit for amplifying the described voltage signal after conversion, and the described voltage signal after amplification is carried out to the A/D converting unit of A/D conversion.
The utility model receives incident light by the light receiving unit of bio-sensing module, sensing unit is in conjunction with the antigen in biomarker, light receiving unit by reflected light back to spectrum acquisition module, under the control of control module, driver module drives spectrum acquisition block motion to determine the final position of characteristic spectrum, and drives the motion of helical orbit resistance to change output resistance; After determining the final position of characteristic spectrum, control module according to the shift offset of the output resistance determination characteristic spectrum of helical orbit resistance, and according to the concentration of shift offset determination biomarker.According to the concentration of the corresponding relation determination biomarker of the output resistance of helical orbit resistance and the concentration of biomarker, avoid the type of biomarker itself and the impact of interference material, thus improve the degree of accuracy of the measurement of concetration to biomarker.
Accompanying drawing explanation
Fig. 1 is the structural representation of apparatus for measuring concentration first embodiment of the utility model high precision biomarker;
Fig. 2 is the structural representation of bio-sensing module in Fig. 1;
Fig. 3 is the structural representation of helical orbit resistance in Fig. 1;
Fig. 4 is the structural representation of the resistor main body of helical orbit resistance in Fig. 3 and the preferred implementation of resistance ligand cooperation;
Fig. 5 is the structural representation of the preferred implementation of apparatus for measuring concentration first embodiment of the utility model high precision biomarker;
Fig. 6 is the structural representation of apparatus for measuring concentration second embodiment of the utility model high precision biomarker;
Fig. 7 is the structural representation of apparatus for measuring concentration the 3rd embodiment of the utility model high precision biomarker.
The realization of the utility model object, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Embodiment
Should be appreciated that specific embodiment described herein only in order to explain the utility model, and be not used in restriction the utility model.
The utility model provides a kind of apparatus for measuring concentration of high precision biomarker, by the corresponding relation of the position of the output resistance of helical orbit resistance, output resistance and characteristic spectrum signal, and the corresponding relation of the shift offset of characteristic spectrum and the concentration of biomarker, determine the concentration of biomarker, to improve the degree of accuracy of the measurement of concetration to biomarker.
With reference to the structural representation that Fig. 1, Fig. 1 are apparatus for measuring concentration first embodiment of the utility model high precision biomarker.
In one embodiment, as shown in Figure 1, the apparatus for measuring concentration of high precision biomarker comprises bio-sensing module 10, spectrum acquisition module 20, control module 30, driver module 40, helical orbit resistance 50 and concentration module 60, wherein:
Bio-sensing module 10 comprises light receiving unit 101 and sensing unit 102; Light receiving unit 101 is for receiving and reflectance signature spectral signal, and sensing unit 102 is in conjunction with the antigen in biomarker;
Spectrum acquisition module 20, is connected with control module 30 and driver module 40, for receiving the characteristic spectrum signal that light receiving unit 101 reflects, and characteristic spectrum signal is sent to control module 30;
Control module 30, is electrically connected with driver module 40, for receive feature spectral signal, and controls driver module 40 and drives helical orbit resistance 50 and spectrum acquisition module 20 to move; And receive the output resistance of helical orbit resistance 50;
Helical orbit resistance 50, is electrically connected with driver module 40, moves the output resistance changing helical orbit resistance 50 under the driving of driver module 40;
Concentration module 60, is arranged at the front end of spectrum acquisition module 20, for aggregation characteristic spectral signal.
With further reference to the structural representation that Fig. 2, Fig. 2 are bio-sensing module in Fig. 1.In the present embodiment, bio-sensing module 10 adopts SPR (Surface Plasmon Resonance, surface plasma resonance technology) biology sensor, as shown in Figure 2, bio-sensing module 10 comprises light receiving unit 101 and sensing unit 102, received the incident light of the specific wavelength from light source by light receiving unit 101, this light receiving unit 101 is prism; Sensing unit 102 is in conjunction with the antigen in biomarker, incident light through light receiving unit 101 receive after through sensing unit 102, decay to a certain degree can be there is after sensing unit 102 absorbs, incident light after decay can reflect away, as the antigen in biomarker is combined with sensing unit 102, surface mass quality then can be caused to change, and reflected light can offset.Particularly, sensing unit 102 comprises the metallic diaphragm 1021 be arranged on light receiving unit 101, and the antibody layer 1022 be arranged on metallic diaphragm 1021, this antibody layer 1022 is in conjunction with the antigen in biomarker, metallic diaphragm 1021 adopts silverskin or golden film usually, antibody layer 1022 is can the antibody that is combined of the various types of antigens in biomarker, when the biomarker in liquid flows through antibody layer 1022, can be combined biochemical reaction occurs with the corresponding antibodies on it.
Spectrum acquisition module 20 is set to photodiode, and this photodiode can receive characteristic spectrum signal that bio-sensing module 10 reflects and be translated into electric signal, and the electric signal after transforming is sent to control module 30; In an initial condition, spectrum acquisition module 20 is arranged at the initial position of characteristic spectrum, namely the antigen in biomarker in conjunction with time reflected light place position, and in the preferred case, the center of spectrum acquisition module 20 overlaps with the center of the initial position of characteristic spectrum, just receives whole characteristic spectrum signals.In one embodiment, suppose that characteristic spectrum signal and ambient light spectrum signal are in a ratio of weak signal, then now, the characteristic spectrum signal magnitude that spectrum acquisition module 20 receives is minimum.In the present embodiment, in order to improve the resolution of systematic survey, the temporary location input aperture of spectrum acquisition module 20 is nanoscale, if the temporary location of spectrum acquisition module 20 is odd number site at the minimum of certain infrared light a bit received, then think the center position of the position of characteristic spectrum at odd number; If the temporary location of spectrum acquisition module 20 is even number site at the minimum of the infrared light that certain a bit receives, then think that the position of characteristic spectrum is in the some position, two, centre being positioned at even number site.Spectrum acquisition module 20 is connected with driver module 40, can under the driving of driver module 40, dynamic receive feature spectrum.
Driver module 40 moves for driving helical orbit resistance 50, and this driver module 40 may be selected to be motor, and be preferably stepper motor in the present embodiment, the step-length of this stepper motor is less, and measuring accuracy is higher.The requirement of the measuring precision should be considered when designing.In the present embodiment, the step-length of stepper motor can be selected to be 0.5 ° or 0.75 °, to ensure the precision measurement of the size to small measurand.
Concentration module 60 pairs of characteristic spectrum signals are assembled, the characteristic spectrum signal of scattering is gathered, to overcome the problems such as the light scattering of characteristic spectrum signal and interference, make being received by spectrum acquisition module 20 of the characteristic spectrum signal maximum of measurement, improve the degree of accuracy of measuring system.This concentration module 60 can adopt condenser, concave-convex lens and LED lamp cup etc. to have the device of optically focused effect, preferably, concentration module 60 and spectrum acquisition module 20 are integrated in one, move under the driving of driver module 40 together with spectrum acquisition module 20, improve the absorptivity of spectrum acquisition module 20 pairs of characteristic spectrum signals in whole process, thus improve measuring accuracy.
When incident light receives through light receiving unit 101, and absorb back reflection to spectrum acquisition module 20 through sensing unit 102, when spectrum acquisition module 20 is positioned at initial position, the output resistance of corresponding helical orbit resistance 50 is also initial resistivity value.Along with characteristic spectrum moves because of the change of determinand, the size of the characteristic spectrum signal that spectrum acquisition module 20 receives can change, when control module 30 judges that the size of this characteristic spectrum signal exceedes preset range, generate corresponding control signal, spectrum acquisition module 20 is driven to move to control driver module 40, until the size of characteristic spectrum signal that spectrum acquisition module 20 receives is in preset range, namely detect that characteristic spectrum signal moves to final position, this position is the present position values of characteristic spectrum signal.Simultaneously, driver module 40 drives helical orbit resistance 50 to move to change the output resistance of helical orbit resistance 50, when characteristic spectrum signal moves to final position, helical orbit resistance 50 stop motion, now the current output resistance of helical orbit resistance 50 corresponds to the present position values of characteristic spectrum signal.Control module 30 is according to the output resistance of helical orbit resistance 50, and the corresponding relation of the position of output resistance and characteristic spectrum signal, determine the present position values of characteristic spectrum signal, and determine the shift offset of characteristic spectrum further, then according to the corresponding relation of the shift offset of characteristic spectrum and the concentration of biomarker, the concentration of biomarker is determined.
Particularly, when detecting that characteristic spectrum signal moves to final position, control module 30 obtains the initial position value of characteristic spectrum and the initial resistivity value of correspondence, according to the corresponding relation of the output resistance of helical orbit resistance 50 and the positional value of characteristic spectrum, this corresponding relation is a linear relationship, because the current output resistance of helical orbit resistance 50 is known, thus the present position values of characteristic spectrum can be determined, according to the distance between the present position values of characteristic spectrum and the initial position value of characteristic spectrum, the shift offset of characteristic spectrum can be determined, then, according to the shift offset of characteristic spectrum and the corresponding relation of biomarker concentration, this corresponding relation is also a linear relationship, just can determine the concentration of biomarker thus.
The present embodiment receives incident light by the light receiving unit 101 of bio-sensing module 10, sensing unit 102 is in conjunction with the antigen in biomarker, light receiving unit 101 by reflected light back to spectrum acquisition module 20, under the control of control module 30, driver module 40 drives spectrum acquisition module 20 to move to determine the final position of characteristic spectrum, and drives helical orbit resistance 50 to move to change output resistance; After determining the final position of characteristic spectrum, control module 30 according to the shift offset of the output resistance determination characteristic spectrum of helical orbit resistance 50, and according to the concentration of shift offset determination biomarker.According to the concentration of the corresponding relation determination biomarker of the output resistance of helical orbit resistance 50 and the concentration of biomarker, avoid the type of biomarker itself and the impact of interference material, thus improve the degree of accuracy of the measurement of concetration to biomarker.
With reference to the structural representation that Fig. 3 and Fig. 4, Fig. 3 are helical orbit resistance in Fig. 1; Fig. 4 is the structural representation of the resistor main body of helical orbit resistance in Fig. 3 and the preferred implementation of resistance ligand cooperation.
Helical orbit resistance 50 comprises resistor main body 501, resistance ligand 502 and resistive 503, wherein:
Resistor main body 501 surface is provided with the first screw thread 5011; Resistance ligand 502 is set in resistor main body 501, and resistance ligand 502 is provided with the second screw thread 5021 with the first screw thread 5011 adaptation; The first end 5031 of resistive 503 is fixed on resistance ligand 502, the second end 5032 of resistive 503 and the surface contact of the first screw thread 5011.
Resistor main body 501 and resistance ligand 502 cooperatively interact, resistance ligand 502 is set in resistor main body 501, resistor main body 501 is set to screw-rod structure, resistor main body 501 surface is provided with the first screw thread 5011, resistance ligand 502 is set to nut structure, the inside surface of resistance ligand 502 is provided with and engages with the second screw thread 5021 with the second screw thread 5021, first screw thread 5011 of the first screw thread 5011 adaptation; The first end 5031 of resistive 503 and the surface contact of the first screw thread 5011 of resistor main body 501, the second end 5032 of resistive 503 is fixed on resistance ligand 502, specifically can be arranged on the second screw thread 5021.
It is the structural representation of the preferred implementation of apparatus for measuring concentration first embodiment of the utility model high precision biomarker with further reference to Fig. 5, Fig. 5.
In the utility model one preferred embodiment, resistor main body 501 is connected with driver module 40, when helical orbit resistance 50 works, resistor main body 501 is driven to rotate by driver module 40, the rotation of resistor main body 501 can drive resistance ligand 502 to move in the horizontal direction, thus drive resistive 503 to move along the surface of the first screw thread 5011, to change the output resistance of helical orbit resistance 50.In other embodiments of the present utility model, also resistance ligand 502 can be connected with driver module 40, when helical orbit resistance 50 works, rotated by driver module 40 Direct driver resistance ligand 502 and move in the horizontal direction, rotate to drive resistor main body 501, thus drive resistive 503 to move along the surface of the first screw thread 5011, to change the output resistance of helical orbit resistance 50.
As shown in Figure 5, in the utility model one preferred embodiment, spectrum acquisition module 20 is arranged on resistance ligand 502, resistor main body 501 and the driver module 40 of helical orbit resistance 50 are mechanically connected, driver module 40 drives resistor main body 501 to move, resistor main body 501 drives resistance ligand 502 to move in the horizontal direction, thus drives spectrum acquisition module 20 to move.
The resistor main body 501 and resistance ligand 502 of helical orbit resistance 50 arrange the first screw thread 5011 and the second screw thread 5021 cooperatively interacted, resistance ligand 502 is made to drive resistive 503 to move on the surface of resistance along the first screw thread 5011, thus change the output resistance of helical orbit resistance 50, in contrast to resistive of the prior art to move along resistor main body rectilinear direction, the utility model embodiment improves the precision of the output resistance of helical orbit resistance 50, meets further in precise hard_drawn tuhes and field of precision measurement the requirement of system accuracy.
With reference to the structural representation that Fig. 6, Fig. 6 are apparatus for measuring concentration second embodiment of the utility model high precision biomarker.
On the basis of above-mentioned the utility model first embodiment, in the second embodiment, the apparatus for measuring concentration of high precision biomarker also comprises:
Slowdown module 70, this slowdown module 70 is connected with driver module 40, for reducing the rotating speed that driver module 40 rotates.
In the present embodiment, slowdown module 70 can be arranged on the output terminal of driver module 40, can be one or more levels speed reduction unit; When driver module 40 works, reduced the rotating speed of driver module 40 by slowdown module 70, thus reduce the torque of driver module 40, measuring accuracy is improved, thus meet measurement demand measuring accuracy being required to higher measuring system.
With reference to the structural representation that Fig. 7, Fig. 7 are apparatus for measuring concentration the 3rd embodiment of the utility model high precision biomarker.
On the basis of above-mentioned the utility model first embodiment, in the 3rd embodiment, the apparatus for measuring concentration of high precision biomarker also comprises:
Signal processing module 80, the output terminal of helical orbit resistance 50 is electrically connected with the input end of signal processing module 80, the output terminal of signal processing module 80 is electrically connected with control module 30, and signal processing module 80 is for carrying out signal conversion, signal amplification and A/D conversion to the output resistance of helical orbit resistance 50.
In the present embodiment, signal processing module 80 specifically comprises resistive voltage signal conversion unit, signal amplification unit and A/D converting unit: resistive voltage signal conversion unit is used for the output resistance of helical orbit resistance 50 to be converted to corresponding magnitude of voltage; Signal amplification unit is used for the magnitude of voltage after to conversion and amplifies, enlargement factor determines the precision of whole system, in signal amplification unit, the enlargement factor of amplifier wants more than 500 times, is designed to multiple-stage filtering and amplification, and the linearity of amplifier interval adopted in the present embodiment is 0.7v ~ 3.6v; A/D converting unit adopts digital to analog converter, and for carrying out analog-to-digital conversion to the magnitude of voltage after amplification, wherein the figure place of digital to analog converter is higher, and measuring accuracy is higher, and the present embodiment selects the digital to analog converter of 24.Concrete circuit connecting relation, those skilled in the art are by the description to this part, then the electric circuit knowledge that combination is grasped can draw, is not repeated herein.
These are only preferred embodiment of the present utility model; not thereby the scope of the claims of the present utility model is limited; every utilize the utility model instructions and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present utility model.
Claims (8)
1. an apparatus for measuring concentration for high precision biomarker, is characterized in that, the apparatus for measuring concentration of described high precision biomarker comprises bio-sensing module, spectrum acquisition module, control module, driver module, helical orbit resistance and concentration module:
Described bio-sensing module comprises light receiving unit and sensing unit; Described light receiving unit is used for receiving and reflectance signature spectral signal, and described sensing unit is in conjunction with the antigen in biomarker;
Described spectrum acquisition module, is connected with described control module and driver module, for receiving the characteristic spectrum signal of described light receiving unit reflection, and described characteristic spectrum signal is sent to described control module;
Described control module, is electrically connected with described driver module, for receiving described characteristic spectrum signal, and controls described driver module and drives described helical orbit resistance and described spectrum acquisition block motion; And receive the output resistance of described helical orbit resistance;
Described helical orbit resistance, is electrically connected with described driver module, moves the output resistance changing described helical orbit resistance under the driving of described driver module;
Described concentration module, is arranged at the front end of described spectrum acquisition module, for assembling described characteristic spectrum signal.
2. the apparatus for measuring concentration of high precision biomarker as claimed in claim 1, it is characterized in that, described sensing unit comprises the metallic diaphragm be arranged on described light receiving unit, and is arranged on the antibody layer on described metallic diaphragm, and this antibody layer is in conjunction with the antigen in biomarker.
3. the apparatus for measuring concentration of high precision biomarker as claimed in claim 1, it is characterized in that, described helical orbit resistance comprises resistor main body, resistance ligand and resistive:
Described resistor main body surface is provided with the first screw thread; Described resistance ligand is set in described resistor main body, and described resistance ligand is provided with the second screw thread with described first threaded adapter; The first end of described resistive is fixed on described resistance ligand, the second end of described resistive and the surface contact of described first screw thread.
4. the apparatus for measuring concentration of high precision biomarker as claimed in claim 3, is characterized in that,
Described resistor main body is connected with described driver module, under the driving of described driver module, drive described resistance ligand to move, described resistance ligand drives described resistive to move along the surface of described first screw thread, to change the output resistance of described helical orbit resistance;
Described spectrum acquisition module is connected with described resistance ligand, and described resistor main body drives described resistance ligand to move under the driving of described driver module, to drive described spectrum acquisition block motion.
5. the apparatus for measuring concentration of high precision biomarker as claimed in claim 1, it is characterized in that, the apparatus for measuring concentration of described high precision biomarker also comprises the slowdown module be connected with described driver module, the rotating speed that described slowdown module rotates for reducing described driver module.
6. the apparatus for measuring concentration of high precision biomarker as claimed in claim 5, it is characterized in that, described slowdown module is first stage decelerator or multi-stage speed reducer.
7. the apparatus for measuring concentration of high precision biomarker as claimed in claim 1, it is characterized in that, the apparatus for measuring concentration of described high precision biomarker also comprises signal processing module, the output terminal of described helical orbit resistance is electrically connected with the input end of described signal processing module, the output terminal of described signal processing module is electrically connected with described control module, and described signal processing module is used for carrying out signal conversion to described output resistance, signal amplifies and A/D conversion.
8. the apparatus for measuring concentration of high precision biomarker as claimed in claim 7, it is characterized in that, described signal processing module comprises the resistive voltage signal conversion unit for being converted to voltage signal to described output resistance, the amplifying unit for amplifying the described voltage signal after conversion, and the described voltage signal after amplification is carried out to the A/D converting unit of A/D conversion.
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| CN201520086599.5U CN204374070U (en) | 2015-02-06 | 2015-02-06 | The apparatus for measuring concentration of high precision biomarker |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016123836A1 (en) * | 2015-02-06 | 2016-08-11 | 深圳市前海安测信息技术有限公司 | Device and method for measuring concentration of biological marker based on spiral resistor |
| WO2016123838A1 (en) * | 2015-02-06 | 2016-08-11 | 深圳市前海安测信息技术有限公司 | System and method for acquiring characteristic spectrum position |
-
2015
- 2015-02-06 CN CN201520086599.5U patent/CN204374070U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016123836A1 (en) * | 2015-02-06 | 2016-08-11 | 深圳市前海安测信息技术有限公司 | Device and method for measuring concentration of biological marker based on spiral resistor |
| WO2016123838A1 (en) * | 2015-02-06 | 2016-08-11 | 深圳市前海安测信息技术有限公司 | System and method for acquiring characteristic spectrum position |
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