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CN1596935A - Medicine for treating baby and child diarrhea and its preparation method - Google Patents

Medicine for treating baby and child diarrhea and its preparation method Download PDF

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Publication number
CN1596935A
CN1596935A CNA2004100124528A CN200410012452A CN1596935A CN 1596935 A CN1596935 A CN 1596935A CN A2004100124528 A CNA2004100124528 A CN A2004100124528A CN 200410012452 A CN200410012452 A CN 200410012452A CN 1596935 A CN1596935 A CN 1596935A
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medicine
kilograms
treatment
infantile diarrhea
rhizoma atractylodis
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CNA2004100124528A
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CN1264543C (en
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马卫猛
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Abstract

A Chinese medicine in the form of ointment for treating infantile diarrhea by applying it onto navel is prepared from 6 Chinese-medicinal materials including white atractylodes rhizome, evodia fruit, aucklandia root, plantain seed, etc through grinding, decocting and mixing it with matrix.

Description

A kind of medicine for the treatment of infantile diarrhea and preparation method thereof
Technical field
The invention belongs to the Chinese Traditional Medicines technical field, relate to medicine specifically by Rhizoma Atractylodis Macrocephalae (parched), Fructus Evodiae, the Radix Aucklandiae, Semen Plantaginis, Endothelium Corneum Gigeriae Galli, Semen Myristicae and other batching treatment infantile diarrhea through grinding, decoct, add the substrate stirring and processing and forming.
Diarrhoea is the common disease of the infant below 10 years old, and the mode of normal at present employing oral anti-inflammatory drug or injection is treated.Though these therapeutic modality curative effects are very fast, the side effect that medicine produced is difficult to the appraisal for the infant that health is in the stage of development.
The application for a patent for invention that application number is 96117162.6, publication number is CN1181249A discloses the Chinese herb medicine of a kind of " paste for treating child diarrhoea ", valuable drugs such as Rhizoma Coptidis, Moschus have been adopted in the Chinese herb medicine of this paste for treating child diarrhoea, and in process for preparation, also must add Colophonium and refine oil, so this medicine exists the defective of cost height and preparation process complexity.
Purpose of the present invention just provides a kind of medicine with good effect, processing technique is simple, cost is low treatment infantile diarrhea.
Second purpose of the present invention just provides the method for the medicine of the above-mentioned treatment infantile diarrhea of preparation.
The technical scheme that realizes the object of the invention is: a kind of medicine for the treatment of infantile diarrhea, and it mainly contains the Chinese herbal medicine composition of following weight portion:
Rhizoma Atractylodis Macrocephalae 5-40 Fructus Evodiae 5-40 Radix Aucklandiae 5-20
Semen Plantaginis 5-20 Endothelium Corneum Gigeriae Galli 10-35 Semen Myristicae 1-9
Treat the medicine of infantile diarrhea, preferably contain the Chinese herbal medicine composition of following weight portion:
Rhizoma Atractylodis Macrocephalae 10-30 Fructus Evodiae 10-30 Radix Aucklandiae 5-15
Semen Plantaginis 5-15 Endothelium Corneum Gigeriae Galli 15-25 Semen Myristicae 2-6
During the more serious summer-heat diarrhoea of treatment infant, in above-mentioned Chinese medicine ingredients, also should contain following parts by weight of Chinese traditional medicine composition:
Herba Pogostemonis 15-25 Rhizoma Atractylodis 5-15 Cortex Phellodendri 15 25
Radix Scutellariae 15-25 Herba Andrographis 5-15 Radix Angelicae Dahuricae 5-15
When the summer-heat diarrhoea of infant is very serious, also should contain the Galla Chinensis of 5-15 weight portion in the above-mentioned medicine;
During the more serious cold diarrhoea of treatment infant, in said medicine, also should contain following parts by weight of Chinese traditional medicine composition:
Rhizoma Zingiberis 5-10 Flos Caryophylli 2-6
Described Flos Caryophylli is a Flos Caryophylli.
The method step for preparing the medicine of above-mentioned treatment infantile diarrhea is:
The first step grinds to form fine powder with the Rhizoma Atractylodis Macrocephalae, two kinds of Chinese herbal medicine of Fructus Evodiae;
After second step decocted remaining Chinese herb medicine water, it was cool to room temperature to take concoction;
The 3rd step added the tablet vinegar of 5-15 weight portion in above-mentioned medicine juice;
The 4th step adding substrate in the medicine juice that adds tablet vinegar stirs and gets final product.
In addition: the fine powder that described Chinese herbal medicine grinds to form is the 80-120 order; The described time that decocts is 30-40 minute; Described substrate is neutral flour.
A kind of medicine for the treatment of infantile diarrhea provided by the present invention and preparation method thereof is compared with prior art and is had the following advantages: one, because medicine of the present invention is Chinese herbal medicine commonly used, the cost of the medicine of prepared one-tenth is a 0.2-0.5 unit, has the low characteristics of cost; Its two because the operation of this medicine of preparation is for grinding, decocting extracting juice and dose substrate and stir, it is simple therefore to have manufacturing procedure; Its three, utilize the diarrheal effective percentage of the infant of this Drug therapy below 10 years old to reach 98%, therefore have the high characteristics of treatment curative effect.
The specific embodiment
Embodiment 1
The first step grinds to form 80 purpose powder after getting 10 kilograms of the Rhizoma Atractylodis Macrocephalaes, 20 kilogram of two flavor of Fructus Evodiae medicine;
Second step was got 4 kilograms of 10 kilograms of the Radix Aucklandiae, 10 kilograms of Semen Plantaginiss, 20 kilograms of Endothelium Corneum Gigeriae Galli and Semen Myristicaes, put into pot and added water to the Myrrha ebuillition of heated, coolly after 30 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 10 liters in the medicine juice of obtaining stirs;
The 4th step added 80 purpose Semen Tritici aestivi powder flour and only is stirred into poultice in the medicine juice that adds tablet vinegar.
Embodiment 2
The first step grinds to form 100 purpose powder after getting 30 kilograms of the Rhizoma Atractylodis Macrocephalaes, 10 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 5 kilograms of the Radix Aucklandiae, 15 kilograms of Semen Plantaginiss, 25 kilograms of Endothelium Corneum Gigeriae Galli, Semen Myristicae and puts into pot for 2 kilograms and add water to the Myrrha ebuillition of heated, coolly after 35 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 15 liters in the medicine juice of obtaining stirs;
The 4th step adding 100 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste and get final product.
Embodiment 3
The first step grinds to form 120 purpose powder after getting 20 kilograms of Rhizoma Atractylodis Macrocephalae (parched)s, 30 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 15 kilograms of the Radix Aucklandiae, 20 kilograms of Semen Plantaginiss, 15 kilograms of Endothelium Corneum Gigeriae Galli, Semen Myristicae and puts into pot for 6 kilograms and add water to the Myrrha ebuillition of heated, coolly after 40 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 6 liters in the medicine juice of obtaining stirs;
The 4th step adding 120 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste as substrate and get final product.
Above embodiment 1-3 is the preparation of the lighter medicine of treatment symptom of diarrhea.
When treatment is diarrhea due to cold pathogen because of the diarrhoea of catching a cold, then adopt the medicine of the preparation of method shown in the embodiment 4-6.
Embodiment 4
The first step grinds to form 90 purpose powder after getting 40 kilograms of the Rhizoma Atractylodis Macrocephalaes, 5 kilogram of two flavor of Fructus Evodiae medicine;
Second step was got 5 kilograms of the Radix Aucklandiae, 20 kilograms of Semen Plantaginiss, 10 kilograms of Endothelium Corneum Gigeriae Galli, 1 kilogram of Semen Myristicae and 10 kilograms of Rhizoma Zingiberiss, Flos Caryophylli is put into pot for 2 kilograms and adds water to the Myrrha ebuillition of heated, and cold to room temperature takes concoction after 40 minutes;
The 3rd goes on foot the vinegar that adds 5 liters in the medicine juice of obtaining stirs;
The 4th step adding 90 purpose Semen Tritici aestivi flour in the medicine juice that adds tablet vinegar are stirred into paste and get final product.
Embodiment 5
The first step grinds to form 90 purpose powder after getting 5 kilograms of the Rhizoma Atractylodis Macrocephalaes, 40 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 15 kilograms of the Radix Aucklandiae, 8 kilograms of Semen Plantaginiss, 35 kilograms of Endothelium Corneum Gigeriae Galli, 7 kilograms in Fructus Amomi Rotundus of system and 8 kilograms of Rhizoma Zingiberiss, Flos Caryophylli (being preferably Flos Caryophylli) and puts into pot for 4 kilograms and add water to the Myrrha ebuillition of heated, coolly after 30 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 15 liters in the medicine juice of obtaining stirs;
The 4th step adding 90 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste and get final product.
Embodiment 6
The first step grinds to form 100 purpose powder after getting 25 kilograms of the Rhizoma Atractylodis Macrocephalaes, 25 kilogram of two flavor of Fructus Evodiae medicine;
Second step was got 20 kilograms of the Radix Aucklandiae, 5 kilograms of Semen Plantaginiss, 20 kilograms of Endothelium Corneum Gigeriae Galli, 9 kilograms of Semen Myristicaes and 5 kilograms of Rhizoma Zingiberiss, Flos Caryophylli (being preferably Flos Caryophylli) is put into pot for 6 kilograms and adds water to the Myrrha ebuillition of heated, and cold to room temperature takes concoction after 40 minutes;
The 3rd goes on foot the vinegar that adds 10 liters in the medicine juice of obtaining stirs;
The 4th step adding 100 purpose Semen Tritici aestivi flour in the medicine juice that adds tablet vinegar are stirred into paste as substrate and get final product.
When infant is because unhygienic diet, improper feeding and because the summer heat type diarrhoea of the taste deficiency-heat that external environment condition (as high temperature), bacteriovirus infection cause, dyspepsia type and symptom seriously the time, then adopt embodiment 7-11 drug prepared:
Embodiment 7
The first step grinds to form 120 purpose powder after getting 15 kilograms of the Rhizoma Atractylodis Macrocephalaes, 35 kilogram of two flavor of Fructus Evodiae medicine;
Second step was got 10 kilograms of the Radix Aucklandiae, 15 kilograms of Semen Plantaginiss, 15 kilograms of Endothelium Corneum Gigeriae Galli, 2 kilograms of Semen Myristicaes and 15 kilograms of Herba Pogostemoniss, 15 kilograms of Rhizoma Atractylodis, 5 kilograms of the Radixs Angelicae Dahuricae, 15 kilograms of Cortex Phellodendris, 25 kilograms of Radix Scutellariaes, Herba Andrographis is put into pot for 5 kilograms and added water to the Myrrha ebuillition of heated, coolly after 40 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 5 liters in the medicine juice of obtaining stirs;
The 4th step adding 120 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste as substrate and get final product.
Embodiment 8
The first step grinds to form 90 purpose powder after getting 35 kilograms of the Rhizoma Atractylodis Macrocephalaes, 20 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 5 kilograms of the Radix Aucklandiae, 10 kilograms of Semen Plantaginiss, 20 kilograms of Endothelium Corneum Gigeriae Galli, 5 kilograms in Fructus Amomi Rotundus of system and 20 kilograms of Herba Pogostemoniss, 10 kilograms of Rhizoma Atractylodis, 10 kilograms of the Radixs Angelicae Dahuricae, 20 kilograms of Cortex Phellodendris, 10 kilograms of Radix Scutellariaes, Herba Andrographis and puts into pot for 10 kilograms and add water to the Myrrha ebuillition of heated, coolly after 35 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 11 liters in the medicine juice of obtaining stirs;
The 4th step adding 90 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste as substrate and get final product.
Embodiment 9
The first step grinds to form 80 purpose powder after getting 15 kilograms of the Rhizoma Atractylodis Macrocephalaes, 15 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 8 kilograms of the Radix Aucklandiae, 5 kilograms of Semen Plantaginiss, 20 kilograms of Endothelium Corneum Gigeriae Galli, 3 kilograms in Fructus Amomi Rotundus of system and 25 kilograms of Herba Pogostemoniss, 10 kilograms of Rhizoma Atractylodis, 15 kilograms of the Radixs Angelicae Dahuricae, 25 kilograms of Cortex Phellodendris, 15 kilograms of Radix Scutellariaes, Herba Andrographis and puts into pot for 15 kilograms and add water to the Myrrha ebuillition of heated, coolly after 40 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 12 liters in the medicine juice of obtaining stirs;
The 4th step adding 80 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste and get final product.
Embodiment 10
The first step grinds to form 100 purpose powder after getting 20 kilograms of the Rhizoma Atractylodis Macrocephalaes, 30 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 9 kilograms of the Radix Aucklandiae, 8 kilograms of Semen Plantaginiss, 15 kilograms of Endothelium Corneum Gigeriae Galli, 4 kilograms in Fructus Amomi Rotundus of system and 15 kilograms of Herba Pogostemoniss, 5 kilograms of Rhizoma Atractylodis, 5 kilograms of the Radixs Angelicae Dahuricae, 15 kilograms of Cortex Phellodendris, 25 kilograms of Radix Scutellariaes, 5 kilograms of Herba Andrographis and Galla Chinensis and puts into pot for 5 kilograms and add water to the Myrrha ebuillition of heated, coolly after 35 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 8 liters in the medicine juice of obtaining stirs;
The 4th step adding 100 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste as substrate and get final product.
Embodiment 11
The first step grinds to form 120 purpose powder after getting 25 kilograms of the Rhizoma Atractylodis Macrocephalaes, 15 kilogram of two flavor of Fructus Evodiae medicine;
Second step got 15 kilograms of the Radix Aucklandiae, 7 kilograms of Semen Plantaginiss, 25 kilograms of Endothelium Corneum Gigeriae Galli, 6 kilograms of Semen Myristicaes and 15 kilograms of Herba Pogostemoniss, 5 kilograms of Rhizoma Atractylodis, 5 kilograms of the Radixs Angelicae Dahuricae, 15 kilograms of Cortex Phellodendris, 25 kilograms of Radix Scutellariaes, 5 kilograms of Herba Andrographis and Galla Chinensis and puts into pot for 15 kilograms and add water to the Myrrha ebuillition of heated, coolly after 30 minutes took concoction to room temperature;
The 3rd goes on foot the vinegar that adds 14 liters in the medicine juice of obtaining stirs;
The 4th step adding 120 purpose flour in the medicine juice that adds tablet vinegar are stirred into paste and get final product.
Utilize the method for above-mentioned prepared plaster treatment infantile diarrhea to be: during use, the cream drug of getting 2-5 gram is applied in the umbilicus place with the infant of warm water wiped clean, and the reuse adhesive plaster firm to paste it, prevents to come off, and changes one time medicine in 24 hours.Generally changing 2-3 time can fully recover, and serious changing can be fully recovered for 4-6 time.
Use for convenience, above-mentioned plaster can also be made plaster.Be about to plaster and be coated on the lining cloth of single face glue, be 1 centimeter square, thick 2-3 millimeter, with plastic foil capping ointment.During use, throw off plastic foil, subsides get final product with the infant umbilicus place of wiped clean.
The applicant adds up 1025 case histories of being treated over 5 years, and wherein that the age minimum is 45 days baby, big 10 one full year of life of less than.In these case histories, 182 of following babies of one full year of life, 351 of the childs of one full year of life to 3 year old, more than 3 years old to 492 of 10 years old children.In above case history, belong to 533 examples that amount to of summer-heat diarrhoea (diarrhea of heat type), belong to 492 examples that amount to of cold diarrhoea (cold diarrhea).Concrete case history is as shown in the table:
Character Symptom the lighter The heavier person of symptom The serious symptom person
The baby Cold diarrhea 63 examples 32 examples
Diarrhea of heat type 52 examples 25 examples 10 examples
The child Cold diarrhea 105 examples 57 examples
Diarrhea of heat type 98 examples 72 examples 19 examples
The child Cold diarrhea 175 examples 60 examples
Diarrhea of heat type 132 examples 105 examples 20 examples
In above-mentioned case history, by medication targetedly, be about to the ointment of 2 millimeters thick, 1 centimeter square size, be applied on the umbilicus of the infant of using the warm water wiped clean, live with the medical proof fabric sealing label, change one time medicine after one day.Symptom is lighter, and to change 1-2 medicine cure rate be 98%, and symptom heavier to change 3-5 cure rate be 95%, effective percentage is 100%, is 88% for the cure rate of serious symptom diarrhea of heat type, effective percentage is 98%.
To being characterized as that above-mentioned diarrhea treatment is observed:
Cure: 1-2 back of medication diarrhoea transference cure, infant is healthy as locating;
Effectively: 2-4 back of medication diarrheal number of times repeatedly is kept to below 4 times by every day, i.e. sx;
Invalid: 4 later diarrheal number of times of medication subtract hardly.
Utilize prepared plaster treatment infant's diarrhoea also to have infant no pain, the easy to use and characteristics that have no side effect.

Claims (10)

1, a kind of medicine for the treatment of infantile diarrhea, it mainly contains the Chinese herbal medicine composition of following weight portion:
Rhizoma Atractylodis Macrocephalae 5-40 Fructus Evodiae 5-40 Radix Aucklandiae 5-20
Semen Plantaginis 5-20 Endothelium Corneum Gigeriae Galli 10-35 Semen Myristicae 1-9
2, a kind of medicine for the treatment of infantile diarrhea as claimed in claim 1 is characterized by described Chinese medicine ingredients and is preferably following weight portion:
Rhizoma Atractylodis Macrocephalae 10-30 Fructus Evodiae 10-30 Radix Aucklandiae 5-15
Semen Plantaginis 5-15 Endothelium Corneum Gigeriae Galli 15-25 Semen Myristicae 2-6
3, a kind of medicine for the treatment of infantile diarrhea as claimed in claim 1 or 2 is characterized by and also includes following parts by weight of Chinese traditional medicine in the described Chinese medicinal ingredients:
Herba Pogostemonis 15-25 Rhizoma Atractylodis 5-15 Cortex Phellodendri 15-25
Radix Scutellariae 15-25 Herba Andrographis 5-15 Radix Angelicae Dahuricae 5-15
4, a kind of medicine for the treatment of infantile diarrhea as claimed in claim 3 is characterized by the Galla Chinensis that also includes the 5-15 weight portion in the described Chinese medicinal ingredients.
5, a kind of medicine for the treatment of infantile diarrhea as claimed in claim 1 or 2 is characterized by and also includes following parts by weight of Chinese traditional medicine in the described Chinese medicinal ingredients:
Rhizoma Zingiberis 5-10 Flos Caryophylli 2-6
6, a kind of medicine for the treatment of infantile diarrhea as claimed in claim 5, it is characterized by described Flos Caryophylli is Flos Caryophylli.
7, preparation a kind of method for the treatment of the medicine of infantile diarrhea as claimed in claim 1 comprises the following steps:
The first step grinds to form fine powder with the Rhizoma Atractylodis Macrocephalae, two kinds of Chinese herbal medicine of Fructus Evodiae;
After second step decocted remaining Chinese herb medicine water, it was cool to room temperature to take concoction;
The 3rd step added the tablet vinegar of 5-15 weight portion in above-mentioned medicine juice;
The 4th step adding substrate in the medicine juice that adds tablet vinegar stirs and gets final product.
8, a kind of method step for the treatment of the medicine of infantile diarrhea of preparation as claimed in claim 7, it is characterized by the fine powder that described Chinese herbal medicine grinds to form is the 80-120 order.
9, a kind of method step for the treatment of the medicine of infantile diarrhea of preparation as claimed in claim 7, it is characterized by the described time that decocts is 30-40 minute.
10, a kind of method step for the treatment of the medicine of infantile diarrhea of preparation as claimed in claim 7, it is characterized by described substrate is neutral flour.
CNB2004100124528A 2004-07-28 2004-07-28 Medicine for treating baby and child diarrhea and its preparation method Expired - Fee Related CN1264543C (en)

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CN1264543C CN1264543C (en) 2006-07-19

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102139000A (en) * 2011-04-02 2011-08-03 封秀花 External medicament for treating simple indigestion of children and preparation method thereof
CN102552425A (en) * 2012-03-07 2012-07-11 王建中 Chinese medicinal composition for treating infantile autumnal diarrhea, and preparation method and application thereof
CN103356721A (en) * 2013-07-12 2013-10-23 石强 Traditional Chinese medicinal composition
CN103690705A (en) * 2013-11-28 2014-04-02 李红冉 Traditional Chinese medicine formula for treating diarrhea
CN104069458A (en) * 2014-07-03 2014-10-01 吴晓青 Traditional Chinese medicine composition for treating infantile anorexia
CN105031570A (en) * 2015-07-04 2015-11-11 青岛云天生物技术有限公司 Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102139000A (en) * 2011-04-02 2011-08-03 封秀花 External medicament for treating simple indigestion of children and preparation method thereof
CN102552425A (en) * 2012-03-07 2012-07-11 王建中 Chinese medicinal composition for treating infantile autumnal diarrhea, and preparation method and application thereof
CN103356721A (en) * 2013-07-12 2013-10-23 石强 Traditional Chinese medicinal composition
CN103690705A (en) * 2013-11-28 2014-04-02 李红冉 Traditional Chinese medicine formula for treating diarrhea
CN104069458A (en) * 2014-07-03 2014-10-01 吴晓青 Traditional Chinese medicine composition for treating infantile anorexia
CN105031570A (en) * 2015-07-04 2015-11-11 青岛云天生物技术有限公司 Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea

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