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CN1284891A - Device for inhaling powdery substances - Google Patents

Device for inhaling powdery substances Download PDF

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Publication number
CN1284891A
CN1284891A CN98813726A CN98813726A CN1284891A CN 1284891 A CN1284891 A CN 1284891A CN 98813726 A CN98813726 A CN 98813726A CN 98813726 A CN98813726 A CN 98813726A CN 1284891 A CN1284891 A CN 1284891A
Authority
CN
China
Prior art keywords
blister pack
described device
pack spare
plate
suction pipe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98813726A
Other languages
Chinese (zh)
Inventor
艾尔弗雷德·冯·舒克曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1284891A publication Critical patent/CN1284891A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Medicinal Preparation (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)

Abstract

The invention relates to producing a blister pack (8) having an inhalation suction tube (3) held thereon in order to puncture the blister pack covering foil (5) and to draw up the content of a blister cavity (6) until it is empty. The invention also relates to a device (V) for inhaling powdery substances from the cavities (6).

Description

Device for inhaling powdery substances
The present invention relates to from the cavity of blister pack spare, inhale the device of powder, this device has on the cover film that is contained in blister pack spare, has the plate of guiding and the plug-in type suction pipe that available hands makes it to move on to from guide hole guide hole, and suction pipe punctures the cover film of blister pack spare with its front end and form the mouthpiece opening on its other end.
This device for inhaling powdery substances is disclosed in DE-OS 196 19 536.Make the suction pipe that self can repeat to insert in each cavity, do location reliably one by one by the guide hole that in fact constitutes the target mesh.In the method, the former cover film of having sealed cup-shaped recess partly is punctured.Suction pipe is leaving in the receiving compartment that keeps to the side to be provided with under the lid that time spent is not closing.
The objective of the invention is to make a kind of similar device for inhaling powdery substances that makes each parts do favourable configuration.
At first with main be to realize this purpose by similar device for inhaling powdery substances with the described feature of claim 1, on concrete arrangement, make suction pipe do detachable clamping along an edge of blister pack spare by adaptor.This just makes suction pipe can do the clamping type clamping.The adaptor that can be connected with blister pack spare makes suction pipe can do the clamping of being convenient to be installed.On the other hand, also requirement can be unclamped this clamping consciously.Arrange the favourable configuration that can obtain spatially along a side.In addition, each parts that connects together can be in stable status each other.This means and to adopt very thin wall body.In addition, adaptor is installed on the blister pack spare by slipping into formula plug-in mounting joint.This can structurally very simply, not need extra link and very economical be achieved.Advantageously: make and slip in the drop-center zone that formula plug-in mounting joint is contained in blister pack spare, bottom land is clipped in therebetween with two coluluses.This two colulus also can resemble and be shaped on adaptor simultaneously the drop-center of blister pack spare.In general, the formula that the slips into plug-in mounting joint with clamping action can meet the demands.But, had better will slip into formula plug-in mounting joint pinning.In this respect, a kind of reversible locking has the following advantages: adaptor can be contained on the new blister pack spare all the time again.But the present invention makes a kind of clamp method of life-time service simple in structure, and suction pipe is clamped in the half housing accessory of adaptor.Corresponding half hull shape shape can provide necessary elasticity or restoring force.The present invention has also made a kind of structure with original creation meaning, makes suction pipe have the flexing arm of radially drawing with respect to suction pipe, and this arm is in the state that connects with respect to plate when advancing plate following blister pack spare.Like this, suction pipe can be described as " living with strap bolt ".The above is flexible and do radially straight drawing with respect to suction pipe and make suction pipe have sufficient one-movement-freedom-degree in each is detained the scope of limiting point.In addition, in this respect, flexing arm can be tacked, specifically, can make this arm have the end of overstriking and this end is in the blister pack spare groove, and do to walk under the slit edge convex shoulder of corresponding extension with the plate groove, like this, brachium is at least about working as with the wide half-phase of plate.This is just in the wide requirement of having satisfied operation in the zone, in plate length in the zone; Slit has also satisfied requirement fully, and slit provides the end limited guide rail to adding butt end.In addition, also make the plate that the comprises adaptor folded plate type cap covers of housing, plate constitutes a middle cover in this housing.Like this, blister pack spare is protected, and does suitable clamped-in style location in housing.For obtaining suitable free charge and discharge operations, make the folded plate type lid manifest the required inlet section of dividing plate that is positioned under the plate, is used for plug-in mounting blister pack spare under the state opening.Corresponding hinge suitably is positioned at the Background Region of housing.Adaptor is positioned at the front of inlet section, is remained on the position of being convenient to take by the suction pipe of described adaptor clamping.In this respect, under the housing closing state, make the folded plate type lid surround adaptor and suction pipe and stay well-to-do protectiveness space in hinge side.In addition, the invention is characterized in: flexing arm is contained on the suction pipe by rotary connecting ring.This has improved operability.The favourable structure of suction pipe accessory is that suction pipe is just with the colulus clamping of its mouthpiece by the adaptor accessory.Another colulus of accessory is used as the surge protection body at the edge of a knife end relative with mouthpiece.This colulus is made the aligning formula and is extended in the front of the sensitivity edge of a knife.In this case, this also means in operation and can not come to harm.In addition, preferably adopt the colulus structure of symmetrical expression design, the people of this left hand easy to use operates, because the very easy reverse plug-in mounting of suction pipe.For clamping arm, also make blister pack spare be provided with spacing block body, this block body prevents that the butt end that adds of flexing arm from deviating from from the position of walking below.This is a kind of state of closure.This block body is contained on the housing by a block.For walking below as mentioned above, a colulus of adaptor has in order to sandwich the groove of flexing arm, and it be very favourable for this to determine.Like this, add butt end and the cross section part of arm just no longer are in the way.A kind of favourable modification is to make adaptor to be installed on the edge of blister pack spare by the push button joint.This relates to and constitutes corresponding button assembly in couples.In a kind of advantageous method, be molded into half button from blister pack spare one sidewall bodies material in this respect.Here it is its protuberance.Corresponding recess is made respective aligned ground and is constituted on adaptor.Preferably in blister pack spare, do not do this arrangement, because the moisture absorption plug-in unit of the blister pack spare of also must packing in the zone between cavity.In this respect, also must in forming the wall body of cavity, be molded into groove and bottom land is positioned at the center on the inner height of blister pack spare thickness plane approximately, and the vertical web that is molded into from the wall body material is stretched out from bottom land, vertically web extends to the rear wall of blister pack spare downwards always, and this rear wall is positioned at a side relative with blister pack spare cover film.This point and make blister pack spare rear wall be positioned at this measure of end of moisture absorption plug-in unit receiving compartment just can be in order to obtain the enclosed space of the moisture absorption plug-in unit of packing into.At last, also make suction pipe locking dactylozoite front end enter connecting the room and embed the locking room of guide hole in the plate guide hole with radial elastic.So just can obtain suction pipe security configuration in use.Lock out action is easy to discover, thereby the end user can assert the correct dormant state that has entered suction.Can be to suction pipe consciously with its dial-out.The locking room also is drawn into the keyed end of locking dactylozoite and connects the room.Textural, can easily form suitable structure the locking room is made of web, this web do to be parallel to the extension at guide hole edge and its thickness less than the height of guide hole.At last, make the upside of web recessed with respect to the plate upside, this is very favourable really.
Below content of the present invention is made more specific description with reference to illustrated embodiment.Among the figure:
Fig. 1 is the perspective view of device for inhaling powdery substances of the present invention, and this device is in dormant state, thereby its plate is exposed outside, and just its housing is opened,
Fig. 2 is the housing front view of closing,
Fig. 3 is its side view,
Fig. 4 is the plane graph of housing,
Fig. 5 is the bottom view of housing,
Fig. 6 is the front view of device, and its folded plate type lid is opened,
Fig. 7 is its side view,
Fig. 8 is the view that is equivalent to Fig. 6, and its blister pack spare is equipped with the adaptor of configuration,
Fig. 9 is its side view,
Figure 10 is the side view of suction pipe,
Figure 11 is its front view,
Figure 12 is the arm side view,
Figure 13 is its front view,
Figure 14 is the adaptor plane graph,
Figure 15 is its side view,
Figure 16 is a blister pack spare plane graph,
Figure 17 is its side view,
Figure 18 is the perspective enlarged drawing of monomer adaptor,
Figure 19 illustrates the corresponding link of blister pack spare,
Figure 20 is the profile of joint between adaptor and the blister pack spare,
Figure 21 be shown in the profilograph of joint,
Figure 22 is the device for inhaling powdery substances dislocation profilograph that is shown with plant suction pipe section,
Figure 23 is the device for inhaling powdery substances dislocation drawing in side sectional elevation that is shown with plant suction pipe section,
Figure 24 is the plane enlarged drawing in blister pack spare cavity district, and the pass in the cover film is shown,
Figure 25 is for comparing the suction pipe front view that has amplified with Figure 22, its front end is provided with the edge of a knife,
Figure 26 is its plane graph,
Figure 27 is the bottom view of suction pipe in edge of a knife side,
Figure 28 is the side view of Figure 25,
Figure 29 is the profilograph of Figure 28,
Figure 30 is the profilograph of Figure 25,
Figure 31 is the perspective view of suction pipe edge of a knife end,
Figure 32 is the blister pack spare decomposing section of Transform Type design,
Figure 33 is its plane graph, and the moisture absorption plug-in unit of configuration more specifically is shown,
Figure 34 is the blister pack spare end-view of combination,
Figure 35 is the plane graph of whole blister pack spare,
Figure 36 is its side view,
Figure 37 illustrates the other end of blister pack spare,
Figure 38 illustrates the corresponding adaptor that does not give tipping,
Figure 39 illustrates the adaptor that gives tipping.
Shown in device for inhaling powdery substances V have a flat substantially plate 1.This plate has the perforate of diagrid shape.Here it is pilot hole 2, layout in a row is made in the hole so that the configuration or the insertion of suction pipe 3 electing property.
Suction pipe 3 has the edge of a knife 4 of a center sheet type band side knife surface at its plant front end.The part 5 that this edge of a knife tensioning vacantly on the cover film 5 that is covered with cavity 6 ' do cutting shape punctures.
Cavity 6 is the cup-shaped recess 7 of a blister pack spare 8.The dark 4mm of being about of cup and cup footpath is about 7.5mm in the inlet region.
Blister pack spare 8 is equipped with powder in many such cavitys 6.The powder of these separating devices is medicated powder 6 for instance.Represent with point-like figure in the drawings.
Cover film 5 is made of aluminium foil.Thin film be attached to blister pack spare 8 above, for instance, can be in the above with its sealing label.
Circular-shaped, concave cavity 6 edges 6 ' the position corresponding with the guide hole 2 of described plate 1 when being contained in blister pack spare 8 usefulness mode easy to use on the plate 1 that the mask effect is seemingly arranged.
So just can insert and take out suction pipe 3 and it is moved on to next guide hole 2, take medicated powder 9 by amount with the accurate dosage that measured.Like this, can correspondingly inhale the drug delivery powder by suction pipe 3 to the predetermined area.For this reason, suction pipe 3 has a mouthpiece opening 10 at its other end.
For medicated powder is flowed, mouthpiece opening 10 is communicated with around the edge of a knife 4 that leads to suction pipe by inhaling medicine passage 11.So just can not have remaining medicated powder ground and inhale empty cavity 6.
For making the medicated powder circulation, inhale medicine passage 11 and be communicated with transversal ventilation mouth 12.This vent leads to the outer surface of suction pipe 3, provides extra air-flow to the band powder central authorities primary air of inhaling empty cavity 6.But vent is positioned at the outside wall surface of decorporating backward from the actual district that holds a writing brush or pen-write of suction pipe 3, and specially is provided with from the outwardly directed strip shape body of vent, thereby makes the unlikely transversal ventilation mouth 12 of blocking of the finger that holds a writing brush or pen-write.In addition, the district that holds a writing brush or pen-write on the outside wall surface is coarse so that strengthen the ability of holding with a firm grip, specifically, is provided with coarse annular cutting.
Suction pipe 3 is installed on the blister pack spare 8.Adaptor 13 carries out plug-in mounting as a suitable connecting plate.This adaptor extends along an edge 14 of blister pack spare 8, and is installed on it.This edge is that profile is the narrow limit or the horizontal edge of rectangular blister pack spare 8.The reference number on another narrow limit is 15.
The detachable suction pipe 3 that carries out clamping by adaptor 13 is installed in the semi-housing shape bracket 16 of adaptor 13.This is a kind of staple joint.This joint by colulus 16 ', 16 " constitute this two coluluses embowment and have identical profile.Described two coluluses are arranged apart from each other in the space, preferably are positioned at two folding corner regions at an edge 14, open towards the plane of plate 1.
Although provide two coluluses 16 ', 16 ", the colulus 16 of also available adaptor 13 supports 16 ' to suction pipe 3 only its mouthpiece end in the drawings left-hand side do to be convenient to the externally-hanging type clamping of gripping.Therefore, " what surround is in order to suction pipe 3 be inserted on that end in the mouth, form mouthpiece opening 10, be substantially cylindrical shape and recessed outer wall section by colulus 16.This is the custom to using the right hand and sinistral people to satisfy its use or be installed simultaneously just.
Also can make the edge of a knife end that is clipped in right side or left side or the edge of a knife 4 in both cases all near colulus 16 ', 16 " the space medial surface can work to have the impact protection all the time.Be positioned at the edge of a knife 4 tips 4 of central authorities ' even can put in the inside of corresponding colulus slightly.The mouthpiece recess is as the axial retention stop portion that is clipped in suction pipe 3 wherein.Corresponding colulus 16 ' or 16 " the inboard be used interchangeably.
Adaptor 13 is contained on the blister pack spare 8 by slipping into formula plug-in mounting joint.Relevant structure can especially clearly be indicated in Figure 18-21.Slipping into formula plug-in mounting joint is a drop-center 17 in the ingredient of blister pack spare one side.This groove leads to edge 14.The wall material that forms groove in drop-center 17 zones is got from the U font of flat covering 18 projections with regard to its section, and covering forms blister pack spare 8 and dark in the above the pressure or horizontal extrusion recess 7 substantially, makes it to same direction projection.
The body of U-shaped wall and two coluluses 19,20 connect with mold form.Colulus is outstanding outside the back 21 of adaptor 13 horizontal stripes 22. Colulus 19,20 connects the end regions overlap joint of side in both sides up and down with blister pack spare 8 on preposition.The bottom land 23 of drop-center 17 and groove side 24 are in the U-shaped interpolation slit 25 that is formed by two coluluses 19,20 in this respect.The U font has orientation.Can prevent to rotate.
Keep to the side 14 front end of following colulus 20 is convergent contour towards interpolation slit 25.This respective front ends to drop-center 17U shape wall has the effect of centering.Section is that the U-shaped limbs of U-shaped have 45 ° of suitable chamferings on U-shaped web and the colulus 20.Stretch into the U-shaped space of colulus 20 to the rectangle section part of last colulus 19 and reserve a slit to form an interpolation slit 25.
The front end that suspends of colulus 19 is convexity with respect to blister pack spare 8 planes in this plane on the finger-like.The one spill end 27 that connects that is positioned at drop-center 17 the inners is contained in the front that connects round 26.
The end of following colulus 20U shape limbs and the upside of horizontal stripe 22 are at a distance of certain distance, this distance equals the gross thickness of lid 18 and blister pack spare 8 cover films 5 at least, edge 14 can be bearing on the back side 21 of adaptor 13, and the while also makes blister pack spare 8 avoid lateral inclination and damages and slip into formula plug-in mounting joint.
In addition, the top edge of last colulus 19 and described horizontal stripe 22 upsides are in sustained height.Constitute the colulus 16 of above-mentioned accessory 16 ' and 16 " stretch out from the middle part of horizontal stripe 22.
As also requiring a kind of fixation except that clamping action in order to avoid member 8 and 13 is deviate from unintentionally to slipping into formula plug-in mounting joint, this just relates to latch shown in a kind of Figure 19-21.Specifically, this relates to a kind of latch convex body 28 that is positioned on the bottom land 23.Latch recess 29 is used for latch convex body 28.Described recess is positioned at the U-shaped web of colulus 20 down.Latch recess 29 forms a through hole.After constituting, this will state the basis of another function of latch.The above convergent contour of emphasizing is very favourable for the inlet that assembling the time enters interpolation slit 25.The excipuliform projection of latch convex body (do certain exaggerative diagram) is being done corresponding fashionable pressurized is shunk back and is forced to be locked in the recess with latch recess 29.Pass through add suitable pulling force and can unclamp this joint again.
Slip into the width of the plug-in mounting length of formula plug-in mounting joint greater than interpolation slit 25.Its ratio is about 2: 1.The plug-in mounting length of colulus 19,20 equal 1/5th of blister pack spare 8 length overalls.
Suction pipe 3 carries out clamping by flexing arm 30 and adaptor 13.Flexing arm holds suction pipe 3 " as the Canis familiaris L. of leading with belt ".Like this, can hold suction pipe and make in its effect " radius " and freely shift in necessity.Arm 30 is radially drawn from long tube type suction pipe 3.Notched annulus 31 is as the instrument that clamps arm 30 in the suction pipe side.Arm 30 can be installed on the waist 33 of suction pipe 3 owing to its radial indentation 32.The periphery of waist is circular, and is just similar to the inside of annulus 31.Therefore, at the following annulus that is shown rotary adapter ring 31 with form the performance that has rotation between the waist 33 of annular groove.
Opening 32 with respect to rotary adapter ring 31 on diametric(al) is connecting cord-like arm 30.On the other end of arm 30, form one and add butt end 34.Just formed a spheroid at this place.The action (referring to Figure 12 and 13) that arm 30 is entad done.
Adding butt end 34 makes arm 30 be clamped on the blister pack spare 8 or on the plate 1.Promote blister pack spare 8 plate 1 time and just can draw suitable link position when (referring to Fig. 8,9) as shown in the figure.For this reason, this plate constitutes a dividing plate 35, and this dividing plate has been considered the corresponding section configuration (referring to Figure 22) of blister pack spare 8.The pod part of guiding blister pack spare is with its parallel vertical lateral margin 8 ' in a narrow sense play a part to have dividing plate 35 leaders, these lateral margins are guiding blister pack spare and the downside of plate 1 continues into a spatial accommodation 36, the cavity 6 (referring to Figure 22 and 23) that the size of this spatial accommodation can be held this space to be formed by recess 7.
The downside of spatial accommodation 36 is a rear wall 37.Rear wall does to be parallel to the extension of plate 1.The longitudinal wall that plate 1 and rear wall 37 are fused is shown 38.Longitudinal wall at 8 one edges of the blister pack spare of making lengthy motion picture shape plug-in mounting 14 and another 15 districts, edge and cross wall 39 fuse.This just forms the housing 40 that configuration is very shallow, be similar to cigarette case.
Plate 1 comprises the adaptor 13 of housing 40, covers with folded plate type lid 41.Plate 1 is as the middle cover of device V housing 40 in this respect.
Folded plate type lid 41 is hinged in the bonding pad of adaptor 13.Corresponding hinge axes is shown 42.This axis is positioned at the end regions of this place's rear wall 37, does to be parallel to the extension of the suction pipe 3 longitudinal central axis line X-X that are clipped in the accessory 16 in the space.Under opening, the section of lid is positioned at the outside of housing section.Because hinge axes 42 arranges slightly backward from the hinge side cross wall of folded plate type lid 41, this just reserve cover side hang body 41 '.This outstanding body and function makes to open spacing block body.Opposed block body is made of the back of this place's rear wall 37.
Suction pipe 3 is clamped when blister pack spare 8 is inserted.For this reason, arm 30 resembles an arrow and is placed in the crossbow groove.Like this, with regard to configuration, form a groove 43 at the upside of top colulus 19, this groove also crosses horizontal stripe 22.The cross dimensions of described groove makes arm 30 unlikely rectangle primary section that outwards exceeds colulus 19 when in fact it stretch out as straight line.In addition, groove 43 opens wide to two ends.Arm 30 length should make under the state of being installed and add the opposite side that butt end 34 drops on drop-center 17 inner end peripheries 27.
Described end periphery becomes a cross wall to extend to the upside of blister pack spare 8.But, upwards have the slit 44 of an opening to disconnect by one than baffle element.This slit can make arm 30 therefrom pass through, and the butt end that adds of arm has a spacing block body 45 on end periphery 27 opposite sides that constitute above-mentioned cross wall, and this block body stops the butt end 34 that adds of flexing arm 30 to break away from its state that tacks (referring to Fig. 6 and 7).Drop-center 17 is shown 17 in that part of the end periphery 27 opposite sides continuity that is only disconnected by slit 44 ' and still be a groove.Groove 17 ' the degree of depth less than drop-center 17 degree of depth that are communicated with adaptor.Groove 17 ' section configuration be semicircle.Its size should make at least become spheroid add partly dropping on wherein of butt end 34.Groove 17 ' formation represents, is used to add the vertical passage of butt end 34 with double-head arrow Y.One end at groove 17 ' close blister pack spare 8 another edges 15 has a spacing block body 46 equally.
The described passage of representing with arrow Y enters housing 40 districts at upside and is stacked in extendible portion on blister pack spare 8 or its dividing plate 35 or overlapping portion is that edgewise convex shoulder 47 by plate 1 downside constitutes.The edgewise convex shoulder 47 that section respectively is 1/4th circular arc, respectively replenish part for the hemispherical passage be as shown in figure 23 be provided with in pairs and constitute a slit 48, though this slit can make arm 30 therefrom pass through, can keep upset end 34 here.When arm 30 was in the state of walking down, " bolt band " was unless make spacing block body 45 throw off can not deviate from from housing 40 again.
The slit 48 that extends in housing 40 vertical central planes provides a movable bite in housing one side for arm 30, and this bite satisfies the requirement that comes back operations fully.For being inserted guide hole 2 required operating radiuses, suction pipe 3 satisfied requirement like this, in the vertical.Equally, span also should meet the demands in the horizontal, and for this reason, the length of arm 30 is at least about equaling plate 1 width partly.
The outlet upside of slit 48 has chamfering.This also be applicable to slit keep to the side 15 end 48 ', slit is in the opposite direction, just have opening towards adaptor 13.Constitute, be shown 49 by chamfering on the slit 48 to the inclined side of external diffusion.This shape helps end 34 joints, is just led and the mobility of the spheroid joint of the clamping that is subjected to float.In addition, owing to make slit 48 be slightly wider than the section of arm 30, also strengthened mobility.
Even suction pipe 3 is in the state that is clamped in the adaptor 13, this arm also can be subjected to the protection of mechanically stressed aspect fully.Drop-center 17 and with form of grooves do straight line continuity and be shown 17 ' part be that to be molded in the wall that constitutes cavity 6 intravital quite deeply.Bottom land 23 is positioned at the planar centre-height of blister pack spare thickness place approximately.The suction pipe 3 central longitudinal axis that are clipped in the accessory 16 also extend in this plane substantially.Like this, radially the arm 30 of An Zhuaning just can not have in the groove 43 that is inserted into suitable extension lateral stressedly.
Because folded plate type lid 41 has well-to-do space 50 in hinge one side, therefore can not produce the power of doing of covering 41 aspects from folded plate type.This well-to-do space 50 can be admitted under no stress in the adaptor 13 substantially by what accessory 16 and suction pipe 3 constituted part independently is set.The collapsible opening of folded plate type lid 41 provides carries out the condition that makes things convenient for of freely taking to adaptor 13, thereby can load onto blister pack spare or take off to exist side by side with the blister pack spare of sky and promptly load onto new blister pack spare 8.Under the swing type opening, inlet section 35 ' and the zone of dividing plate 35 upper and lower sides be to open wide fully.
Although the carry limit formula supporting of blister pack spare 8 in slit 35 adds that spatial accommodation 36 has met the demands, but the modification by blister pack spare 8 shown in Figure 32 newly designs a kind of method that adopted, in the method, be provided with the vertical web 51 that is molded into from blister pack spare 8 wall material.In addition, the wall material is made angular bend along periphery in the case.The peripheral narrow wall that curves like this is shown 52.The shape that this has described blister pack spare 8 to can be described as housing rather than the shape of plate body.Vertically the narrow limit and the limit wall 52 of web 51 are in the same plane with its end.
Vertically web 51 from drop-center 17 or groove 17 ' the outside stretch out.This foaming structure of making as mould notes part has been considered above-mentioned cavity 6 equally.Used reference number is identical.
The shell mould foaming structure has rear wall 53 in the side away from plate 1.This just forms an end face with extraneous packing.Cavity 6 that medicated powder 9 is housed here is still to be sealed with cover film 5 as mentioned above.The blister pack spare of finishing 8 is shown in Figure 34,35 and 36.
In the zone on making stand-by blister pack spare 8 between cavity 6 or the cup-shaped recess 7 moisture absorption plug-in unit 54 is housed.Plug-in unit is the shape of small pieces and is contained in the gap 55 that four equidistant cavitys 6 are reserved (referring to Figure 33) by certain position.
Blister pack spare rear wall 53 is enclosed in the groove 17/17 ' both sides cavity 56 that extends in vertical central plane.Hygroscopic effect just independently distributes in the cavity at these two.The height of plug-in unit 54 is identical with cavity 56.The rear wall 53 that is made of aluminium foil just provides a kind of good supporting like this, for instance.
Rear wall 53 and vertical web 51 are bearing in the inboard or the upside of housing 40 rear walls 37.Much less, the downside of cup-shaped recess 7 also may extend into described upside or extends to the upside of blister pack spare rear wall 53.
Shown in figure 32, adaptor 13 is not to be connected with blister pack spare 8 with carvel joint, that is to say, adaptor does not overlap with the profile of blister pack spare 8.Different therewith, adaptor 13 is connected with an edge 14 by a push button joint in the case, specifically, is to utilize the limit wall 52 of edge being bent angularly to connect in the case.This can be referring to Figure 37.
One button half one 57 that constitutes protuberance is that horizontal making come from the sidewall material of described blister pack spare 8.Corresponding therewith recess is positioned at the horizontal stripe 22 of adaptor 13.The push button joint is to design from the notion that pressurization engages, thereby can consciously adaptor 13 be unloaded from the blister pack spare that connects with it.As button half one 57 of protuberance have the mushroom capitiform, laterally have groove, have the convex body of thin handle.The mushroom of a Xing Chenging thickened portion just may be stuck in behind another button half 59 necks that constitute recess on the shoulder 58 thus.In addition, adopted identical reference number for the ease of understanding; Here also leave the leeway of selection, just, the edge of a knife 4 is aimed at the right or the left side of adaptor 13 accessories 16.
The edge of a knife 4 has stent-type or frame-type blade.For the guiding and the location of the circular extension that is subjected to cavity 6, make described blade extend (referring to Figure 24) along diameter line D-D.Otch almost reach the inner edge 6 of cavity 6 '.At first, point of a knife 4 ' the thrust cover film 5 that is positioned at central authorities seal the part 5 of cavity ' central authorities." penetrate and cut, the edge of a knife outside is made the roof type ramped shaped and is fallen and do central authorities' cutting to make the outside 4 of the edge of a knife 4 then.The angle α in the edge of a knife outside 4 ", 4 " is about 120 °.Symmetrical expression extension (referring to Figure 24) is done with respect to the central longitudinal axis X-X of suction pipe 3 in the roof type slope.
The frame-type hollow space of blade is shown 60.This part lead to cutter head and with inhale powder passage 11 and do circulation with ventilation cross-drilled hole 12 and be connected.This part constitutes the dividing plate of inhaling band opening in the powder passage.
Extending plate 61 along the edge of a knife 4 both sides of diameter layout, adjacent flank ground separated by a distance with the edge of a knife, that form the edge of a knife.Plate face 61 after its impact type that suspends ' with the edge of a knife 4 on the periphery that exposes compare significantly and axially shrink back backward.Described plate 61 is separated by a distance with the side of the edge of a knife 4 and do parallel extension by the side.
Plate 61 is as the passing instrument.Plate to the cover film 5 that punctures suspend tensioning portion 5 ' the channeling conduct of joint-cutting edge, make its inner edge that stretches to cavity 6 conscientiously 6 '.This just leaves a hole that section is very big.Therefore, concerning powder 9, can very advantageously flow out cavity 6.
Therefore, as shown in figure 24, can obtain the breach of repeatability all the time.Plate 61 breaks the breach of cutting in advance and it is further pushed back the edge of a knife 4 both sides.Thereby draw outward extending paired wedge-like portion, its submarginal wedge shaped tip is shown 62.This just draw by plate 61 force the tongue shape tabs 63 that is attached on the cavity edge and by seaming and cutting cause, in wedge-like portion 65 and a triangle between the above-mentioned wedge-like portion 62 or a dihedral central flaps 64 that is on the diameter line D-D.
Plate 61 also can have sharp edge as shown in the figure, and this can be very favourable for its traction.
Spacing between the plate 61 is identical with the width that blade framework hollow space 60 is measured on bigger edge of a knife width.Headroom section obviously narrower on the suction pipe 3 joins with the big headroom internal diameter that constitutes suction powder passage U at the root of two members 60,61.Ventilation cross-drilled hole 12 also is located in and forms in the bigger part of this section.
Be provided with the spacing convex body 66 of insertion of suction pipe 3 front ends that are used for to insert guide hole 2 in lower area symmetrically at ventilation cross-drilled hole 12.Be positioned at downside, do etc. angular distribution four substantially and insert spacing convex bodys 66 and make the marginal zone in hole be positioned at the upside of plate 1 guide hole 2.On this position, just can obtain the best insertion depth of the edge of a knife 4 with respect to cavity.
For making the easier grasp of end user, suction pipe 3 has the measure that is locked on the plate 1.For this reason, the front end at suction pipe 3 forms locking dactylozoite 67.Described locking dactylozoite is parallel to that the edge of a knife 4 suspends that shape extends and its end is toward the outer side locking shape 68.Lock out action is conspicuous.
When plug-in mounting suction pipe 3, locking dactylozoite 47 also enters the guide hole 2 that constitutes on the plate 1 of covering plate.
Locking dactylozoite 67 is positioned at the outside of guide hole 2 circular sections, thereby the cross section of the distribution channel that do not account for.Connect room 69 as what the corresponding admittance cavity of locking dactylozoite 67 was provided with equal number, this locking dactylozoite enters the back of guide hole 2 peritremes.Vertically arrange as shown in Figure 1 along housing 40 with respect to guide hole in a row in the described room that connects.Connecting the room is arranged on the common diameter line of guide hole 2.This line can be used as the layout trend of the suction pipe 3 corresponding edges of a knife.Describedly connect room 69 this just is on the direction of insertion, but enter locking room 70 (referring to Figure 22) at plate 1 downside simultaneously.This locking room is by doing a side 68 of lateral arrangement ' block with respect to direction of insertion on the elongated insertion part 68 from following.Described side 68 ' and suction pipe 3 can be withdrawed from from the position that it blocks consciously more not really suddenly.Therefore, locking dactylozoite 67 is inwardly done the resilient radial action in short time in latched connects.Keyed end 68 sides 68 ' radial width equal between suction pipe 3 edge of a knife ends and locking dactylozoite 67 back sides space 71 at least to edge of a knife lateral deviation is moved.
As shown in figure 22, locking room 70 forms by web 72, and web strides across guide hole in a row connects together plate 1.These webs therefore do to be parallel to the extension at guide hole edge and its thickness less than the length or the height of guide hole 2.Locking room 70 has reduced the vertical height of web 72.At upside recess is arranged also in this respect.The upside of web 72 is recessed significantly with respect to plate 1.Like this, if the air inlet of described for a certain reason guide hole 2 is obstructed, just have the distribution network 73 that leads to adjacent passages 2.In a word, should take measures to make the periphery of the edge of a knife 4 and plate 61 to have enough suction air-flows.Flow into path accordingly based on the skew gained of corresponding wall body and in Figure 23, be shown 74.Plate 61 makes the effect that has passing and keep aspect cover film 5 appropriate sections 5 ' break and the turnover, and from then on this also find out among the figure.
With regard to described another effect of locking recess 29, what must illustrate is: recess also with another locking convex body 75 of case side interact (referring to Figure 21).This convex body from housing 40 rear walls, 37 inside protrusions and with its excipuliform structure in this enters the hole.Like this, adaptor 13 and the blister pack spare 8 that suspends on it can only be pulled out in the housing 40 of device V consciously.
Also the edge 15 that blister pack spare 8 parts can be exposed outwards promotes so that take out blister pack spare 8 from housing 4 ends at this place.This is to obtain this suitable operation by the room 76 in the plate 1, this room dividing plate 35 of spatial accommodation 36 adjacency in cross-section and this end regions plate 1 in.In addition, room 76 interacts with the convex body 78 that can suitably insert.This convex body is positioned on the folded plate type lid 41 inboard suitable positions.
78 pairs of hinge axes 42 of this joint convex body have protective effect.In addition, engage convex body 78 and also can make folded plate type lid 41 keep the lock bolt of closing in order to formation, the pairing body of its lock bolt be positioned at the corresponding site in room 76.
Form shown in Figure 1 also can make suction pipe 3 be connected with plate 1 by flexing arm (as a rope), but slave plate 1 a central fixing point is drawn (length of arm 30 is enough to reach all guide holes 2), and it is interior and be not subjected to the restriction of blister pack spare 8 also can to make spheroid 34 still be clipped in slit 49.The colulus 16 so slit 49 can be sealed at two ends ' and 16 " can be contained on the plate 1.
Spheroid 34 and so on is become movably and be clamped in the groove, preferably be clamped in the drop-center 17 of blister pack spare 8, in the case adaptor 13 also can be shifted thereupon or replace another kind of clamping device so as with suction pipe 3 in that the time spent is not fixed on the blister pack spare.
All features that disclose are being the most basic to the present invention.In addition, listed the relevant disclosure of property data (Xerox of former first to file) in advance in as extention in the present disclosure of the invention, this is for the feature in these data is also included within claims of the application.

Claims (29)

1. blister pack spare (8) has the suction pipe (3) of clamping on it, and suction pipe is in order to puncture blister pack spare cover film (5) and to inhale an empty foaming cavity (6).
2. in order to draw the device (V) of powder from the cavity (6) of blister pack spare (8), have: a plate (1) engages in blister pack spare cover film (5) top and has a guide hole (2); With an insertable suction pipe (3), available hands makes it move on to guide hole (2) and puncture blister pack spare cover film (5) with its front end from guide hole (2), suction pipe forms a mouthpiece opening (10) at its other end, it is characterized in that: suction pipe (3) is by an edge (14) the quilt separably clamping of an adaptor (13) along blister pack spare (8).
3. press the described device of claim 1, or particularly by the described device of aforementioned claim, it is characterized in that: adaptor (13) slips into formula plug-in mounting joint by one and is contained on the blister pack spare (8).
4. by one or more of in the above claim, or the described device of particularly aforementioned claim, it is characterized in that: slip into formula plug-in mounting joint be contained in blister pack spare (8) drop-center (17) the zone in and have two coluluses (19,20), at the bottom of receiving channel between this two colulus (23).
5. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: slip into formula plug-in mounting joint (28/29) and lock.
6. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: suction pipe (3) is installed in half shelly accessory (16) of adaptor (13).
7. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: suction pipe (3) has a flexing arm (30), this arm with respect to the suction pipe radial finger to, this arm enters a connection status with respect to plate (1) in the time of below blister pack spare (8) being shifted onto plate (1).
8. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: arm (30) has one and adds butt end (34), this end is inserted under blister pack spare groove (17 ') the edgewise convex shoulder (47) interior and a slit (48) in plate (1) and walks, this slit correspondingly extends with respect to groove (17 '), and the length of arm (30) is at least about equaling plate (1) width partly.
9. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: the plate (1) of packing adaptor (13) is covered by the folded plate type lid (41) of housing (40), and plate (1) constitutes an inter panel in this housing (40).
10. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: make and be positioned at plate (1) below and display opening state lower flap portion formula lid (41) in order to the entrance section (35 ') of the compartment (35) that inserts blister pack spare (8).
11. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: folded plate type lid (41) surrounds adaptor (13) and suction pipe (3) by a hinge side free space (50).
12. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: flexing arm (30) is contained on the suction pipe (3) by the ring (31) that is rotatably connected.
13., it is characterized in that by one or the described device of multinomial or particularly aforementioned claim in the above claim: suction pipe (3) only with its mouthpiece side end by a colulus of the accessory (16) of adaptor (13) (16 ' or 16 ") give clamping; One second colulus of accessory (16) (16 ' or 16 ") be set in place edge of a knife end as surge protection spare in relative part.
14. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: the groove (17 ') of blister pack spare (8) is provided with a spacing block body (45), this block body prevent flexing arm (30) add in the position that butt end (34) walks from below.
15. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: a colulus (19) of adaptor (13) has in order to insert the groove (43) of flexing arm (30).
16. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: adaptor (13) is located by the edge (14) that a push button connector clamp is held in blister pack spare (8).
17. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: button half one (57) is molded into from blister pack spare (8) side-wall material.
18. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: blister pack spare (8) has moisture absorption plug-in unit (54) in the zone between cavity (6).
19. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: groove (17,17 ') is molded in the wall body that forms cavity, the planar central authorities that bottom land (23) approximately is positioned at blister pack spare thickness highly locate, and the vertical web (51) that is molded into from the wall body material stretches out and extends to blister pack spare rear wall (53) blister pack spare rear wall (53) and be positioned at a side relative with blister pack spare cover film (5) from wall body.
20. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: blister pack spare rear wall (53) is sealed the admittance cavity (56) that is used for moisture absorption plug-in unit (54).
21. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: locking dactylozoite (67) is arranged on the front end of suction pipe (3), and this locking dactylozoite with radial elastic enters the connecting in the room (69) and snap in the locking room (70) of guide hole (2) of guide hole (2) of plate (1).
22. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: locking room (70) is made of web (72), and this web is parallel to the extension of guide hole edge and has less than guide hole (2) thickness highly.
23. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: web (72) upside is recessed with respect to the upside of plate (1).
24., it is characterized in that: engage in blister pack spare (8) top and plate (1) with guide hole (2) is connected with suction pipe (3) by flexing arm (30) by the described device of one or more of or particularly aforementioned claim in the above claim.
25. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: a fixing point of the plate side one end slave plate (1) of arm (30) stretches out.
26. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: plate side one end of arm (30) can move in vertical slit (49) of plate (1).
27. by the described device of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: mobility obtains by a slit guide groove, a spheroid that is contained in arm (30) end moves in the blocked mode of form in this slit guide groove.
28. by the described blister pack spare of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: plate side one end of flexible wall (30) is clamped in the slit of blister pack spare (8) and can moves within it.
29. by the described blister pack spare of one or more of or particularly aforementioned claim in the above claim, it is characterized in that: the end of flexing arm (30) is contained on the fixing point of blister pack spare, and the length of arm (30) equals the distance from the farthest cavity at least.
CN98813726A 1997-12-22 1998-12-22 Device for inhaling powdery substances Pending CN1284891A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19757208.1 1997-12-22
DE19757208A DE19757208A1 (en) 1997-12-22 1997-12-22 Blister pack useful for inhalation of contents

Publications (1)

Publication Number Publication Date
CN1284891A true CN1284891A (en) 2001-02-21

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CN98813726A Pending CN1284891A (en) 1997-12-22 1998-12-22 Device for inhaling powdery substances

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EP (1) EP1045711A1 (en)
JP (1) JP2001526096A (en)
KR (1) KR20010033411A (en)
CN (1) CN1284891A (en)
AU (1) AU751738B2 (en)
BR (1) BR9814371A (en)
CA (1) CA2316345A1 (en)
DE (1) DE19757208A1 (en)
EE (1) EE200000399A (en)
HU (1) HUP0100589A3 (en)
IL (1) IL136878A0 (en)
NO (1) NO20003182L (en)
NZ (1) NZ505272A (en)
PL (1) PL341319A1 (en)
SK (1) SK9542000A3 (en)
TR (1) TR200001862T2 (en)
WO (1) WO1999032179A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010029947A1 (en) * 1999-12-17 2001-10-18 Steve Paboojian Receptacles to facilitate the extraction of powders
DE19961300A1 (en) * 1999-12-18 2001-06-21 Asta Medica Ag Storage system for medicinal products in powder form and inhaler equipped with them
SE9904705D0 (en) * 1999-12-21 1999-12-21 Astra Ab An inhalation device
US7258118B2 (en) 2002-01-24 2007-08-21 Sofotec Gmbh & Co, Kg Pharmaceutical powder cartridge, and inhaler equipped with same
DE102007005724A1 (en) * 2007-01-31 2008-08-07 Behr Gmbh & Co. Kg air vents
FR2918352B1 (en) 2007-07-03 2009-10-09 Valois Sas TANK OPENING DEVICE FOR FLUID PRODUCT DISPENSING DEVICE
EP2082763A1 (en) 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhaler
DE102017106500A1 (en) * 2017-03-27 2018-09-27 Aixtron Se powder feeder

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5133454A (en) * 1990-12-06 1992-07-28 Hammer Steven G Intravenous catheter biohazard prevention packaging device
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
DE19619536A1 (en) 1996-04-25 1997-10-30 Alfred Von Schuckmann Inhaler device
RU2181603C2 (en) * 1996-04-25 2002-04-27 Астразенека Аб Inhaler

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SK9542000A3 (en) 2000-11-07
AU751738B2 (en) 2002-08-29
EP1045711A1 (en) 2000-10-25
JP2001526096A (en) 2001-12-18
NO20003182D0 (en) 2000-06-19
DE19757208A1 (en) 1999-06-24
TR200001862T2 (en) 2001-01-22
IL136878A0 (en) 2001-06-14
EE200000399A (en) 2002-02-15
WO1999032179A1 (en) 1999-07-01
NO20003182L (en) 2000-08-21
CA2316345A1 (en) 1999-07-01
HUP0100589A1 (en) 2001-06-28
BR9814371A (en) 2003-01-28
AU2163299A (en) 1999-07-12
HUP0100589A3 (en) 2001-07-30
PL341319A1 (en) 2001-04-09
KR20010033411A (en) 2001-04-25
NZ505272A (en) 2002-05-31

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