CN113855933A - But injection moulding two-chamber embedment syringe in advance - Google Patents
But injection moulding two-chamber embedment syringe in advance Download PDFInfo
- Publication number
- CN113855933A CN113855933A CN202111149536.6A CN202111149536A CN113855933A CN 113855933 A CN113855933 A CN 113855933A CN 202111149536 A CN202111149536 A CN 202111149536A CN 113855933 A CN113855933 A CN 113855933A
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- section
- liquid
- powder
- piston
- liquid section
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000001746 injection moulding Methods 0.000 title description 6
- 239000007788 liquid Substances 0.000 claims abstract description 70
- 239000000843 powder Substances 0.000 claims abstract description 49
- 238000002347 injection Methods 0.000 claims abstract description 21
- 239000007924 injection Substances 0.000 claims abstract description 21
- 230000001681 protective effect Effects 0.000 claims abstract description 6
- 238000007789 sealing Methods 0.000 claims description 7
- 230000009977 dual effect Effects 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 11
- 239000003708 ampul Substances 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 4
- 239000000284 extract Substances 0.000 abstract description 2
- 239000011521 glass Substances 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 description 3
- 238000004108 freeze drying Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000009455 aseptic packaging Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229940071643 prefilled syringe Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses an injection-moldable double-cavity pre-encapsulated injector which comprises a needle cylinder, wherein the needle cylinder consists of a powder section and a liquid section, one end of the powder section is hermetically connected with one end of the liquid section, the other end of the powder section is provided with a needle head protective cap, a piston is arranged in the liquid section, the piston is fixedly connected with one end of a push rod, and the piston is in sliding fit with the inside of the liquid section; be equipped with in the liquid section and can follow the gliding removal piston of liquid section inner wall, the one end of connecting powder section on the liquid section is equipped with 1 at least other chamber, and the inner chamber intercommunication of other chamber and liquid section, the length in other chamber is greater than the thickness of removing the piston. The invention avoids the falling scraps produced by repeatedly puncturing the rubber bottle plug by the injection needle, the glass scraps produced when opening the ampoule and the pollution of the outside air to the liquid medicine; the residue generated when the disposable plastic syringe extracts the injection and the liquid medicine is avoided; the sharpness of the injection needle is kept; simplifying the production procedure of pharmaceutical factory.
Description
Technical Field
The invention relates to a double-cavity pre-filled and sealed syringe, in particular to an injection-moldable double-cavity pre-filled and sealed syringe, and belongs to the technical field of medical syringes.
Background
The prior pharmaceutical powder injection is packaged in bottles by using injection tubes, and an ampoule for containing injection and a disposable plastic sterile injector are required to be arranged when in use. The using process is as follows: and opening the ampoule, sucking the injection by using a disposable injector, injecting the injection into an injection tube bottle to dissolve the powder into a solution, and then extracting the solution by using the injector to finally finish injection. The whole injection operation process is complicated, and secondary pollution is easily caused by repeated suction and puncture.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: how to avoid the problem of secondary pollution caused by repeated suction and puncture of the ampoule.
In order to solve the technical problems, the technical scheme of the invention is to provide an injection molding double-cavity pre-filling and sealing injector which is characterized by comprising a needle cylinder, wherein the needle cylinder consists of a powder section and a liquid section, one end of the powder section is hermetically connected with one end of the liquid section, the other end of the powder section is provided with a needle head protective cap, a piston is arranged in the liquid section, the piston is fixedly connected with one end of a push rod, and the piston is in sliding fit with the inside of the liquid section; a movable piston capable of sliding along the inner wall of the liquid section is arranged in the liquid section, at least 1 side cavity is arranged at one end of the liquid section, which is connected with the powder section, the side cavity is communicated with the inner cavity of the liquid section, and the length of the side cavity is greater than the thickness of the movable piston; a sealed cavity is formed among the movable piston, the piston and the inner wall of the liquid section.
Preferably, the powder section and the liquid section are mutually matched and connected through threads; the outer wall of one end of the liquid section is provided with an external thread, and the inner wall of one end of the powder section is provided with an internal thread matched with the external thread; and a sealing structure is arranged between the powder section and the liquid section.
Preferably, the sealing structure comprises a wedge-shaped structure concave surface and a wedge-shaped structure convex surface which are mutually matched and connected, and a wedge-shaped structure concave surface is arranged between the external thread and the inner wall of the liquid section; lie in the internal screw thread one end in the powder section and be connected with the joint design, be equipped with wedge structure convex surface between the outer wall of joint design and the powder section inner wall, be equipped with the recess that matches with wedge structure concave surface between the outer wall of internal thread and joint design, the close cover of wedge structure concave surface pastes on wedge structure convex surface.
Preferably, a sealed cavity of the liquid section is filled with liquid medicine; the powder section is filled with freeze-dried powder.
The powder section and the liquid section can be directly formed by injection molding, so that large-scale production can be realized, and the powder section and the liquid section are separately filled, so that the production efficiency can be improved. By arranging the side cavity in the liquid section, when the injection device is used, the dissolving liquid and the movable piston are pushed to the side cavity through the push rod, and the liquid medicine flows into the front powder from the side cavity and then continues to be injected.
The invention adopts a double-cavity design, integrates a tube bottle, an ampoule and a disposable plastic syringe into a whole, and is convenient for clinical application; the pollution of dropping scraps generated by repeatedly puncturing the rubber bottle plug by the injection needle, glass scraps generated when opening the ampoule and outside air to the liquid medicine is avoided; the matching dosage is more accurate, and the residue generated when the disposable plastic syringe extracts the injection and the liquid medicine is avoided; the sharpness of the injection needle is kept, the influence of repeated puncture of the needle point on the sharpness is avoided, and the pain of a patient during injection is reduced; simplifying the production procedure of pharmaceutical factory. The product is subjected to cleaning, silicification and sterilization treatment, and aseptic packaging is adopted, so that a tubular bottle cleaning and filling machine and an ampoule cleaning and filling machine are not required to be used, and the production can be finished only by a pre-filling and sealing syringe filling and packaging machine.
Drawings
FIG. 1 is a schematic illustration of an injection moldable dual chamber pre-filled syringe;
FIG. 2 is a schematic view of a powder segment;
fig. 3 is a schematic view of a liquid segment.
Detailed Description
In order to make the invention more comprehensible, preferred embodiments are described in detail below with reference to the accompanying drawings.
The invention provides an injection molding double-cavity pre-filling and sealing injector, which comprises a needle cylinder, a piston 2, a push rod 1 and a needle head protective cap 6, wherein the needle head protective cap 6 is arranged at the top end of the needle cylinder, the push rod 1 fixed with the piston 2 is arranged in the needle cylinder, and the piston 2 is in sliding fit with the interior of the needle cylinder, as shown in figures 1-3.
The cylinder is connected to form through screw thread intermeshing by powder section 5 and liquid section 4, and powder section 5 and liquid section 4 injection moulding respectively set up syringe needle safety cap 6 on the 5 top in powder section, and liquid section 4 is inside to be set up push rod 1 that is fixed with piston 2, piston 2 and the inside sliding fit of liquid section 4.
The outer wall of the liquid section 4 is provided with an external thread 41, and a wedge-shaped concave surface 42 is arranged between the external thread 41 and the inner wall of the liquid section 4. The inner cavity of the liquid section 4 is internally provided with a movable piston 3, the movable piston 3 can slide up and down along the inner wall of the liquid section 4, the movable piston 3 and the piston 2 seal the inner cavity of the liquid section 4 up and down, and liquid medicine 8 can be placed. At least 1 side cavity 43 is arranged on the inner pipe wall of the end of the liquid section 4 close to the movable piston 3, the side cavity 43 is communicated with the inner cavity of the liquid section 4, and the length of the side cavity 43 is slightly larger than the thickness of the movable piston 3. When the movable piston 3 moves to the side cavity 43, two ends of the side cavity 43 are respectively arranged at two sides of the movable piston 3 and are respectively communicated with the powder section 5 and the liquid section 4. The powder section 5 is provided with an internal thread 51, and a wedge-shaped convex surface 52 for being matched with the wedge-shaped concave surface 42 of the liquid section 4 is arranged in the powder section 5. Lie in the one end of internal thread 51 on powder section 5 and be connected with joint design 53, be equipped with wedge structure convex surface 52 between joint design 53's outer wall and 5 inner walls of powder section, be equipped with the recess that matches with wedge structure concave surface 42 between internal thread 51 and joint design 53's the outer wall, wedge structure concave surface 42 closely overlaps pastes on wedge structure convex surface 52, reaches sealed effect. The wedge-shaped structure on the powder segment 5 is. The powder section 5 and the liquid section 4 are respectively filled with freeze-dried powder 7 and liquid medicine 8.
In this embodiment, the number of the side cavities 43 is 2; when the movable piston 3 is pushed to one side of the side cavity 43, a passage is formed at the two ends, so that the liquid medicine 8 can flow in conveniently.
Before the needle is used, the needle head protective cap 6 can be pre-installed on the needle head at the top end of the powder section 5, then liquid filling is carried out in the powder section 5, freeze-drying is carried out to form freeze-dried powder 7, and the powder section 5 and the liquid section 4 are assembled together after freeze-drying is finished.
When the injection is used, the liquid medicine 8 and the movable piston 3 are pushed to the side cavity 43 through the push rod 1, the liquid medicine 8 flows into the front from the side cavity 43, the freeze-dried powder 7 is dissolved, and then the injection is continuously carried out.
The invention is equally applicable to other compositions, for example, where two different gases are placed in the powder section 5 and the liquid section 4, respectively, and then mixed by the invention.
Claims (4)
1. The injection-moldable double-cavity pre-filled and sealed injector is characterized by comprising a needle cylinder, wherein the needle cylinder consists of a powder section (5) and a liquid section (4), one end of the powder section (5) is hermetically connected with one end of the liquid section (4), the other end of the powder section (5) is provided with a needle head protective cap (6), a piston (2) is arranged inside the liquid section (4), the piston (2) is fixedly connected with one end of a push rod (1), and the piston (2) is in sliding fit with the inside of the liquid section (4); a movable piston (3) capable of sliding along the inner wall of the liquid section (4) is arranged in the liquid section (4), at least 1 bypass cavity (43) is arranged at one end of the liquid section (4) connected with the powder section (5), the bypass cavity (43) is communicated with the inner cavity of the liquid section (4), and the length of the bypass cavity (43) is greater than the thickness of the movable piston (3); a sealed cavity is formed among the movable piston (3), the piston (2) and the inner wall of the liquid section (4).
2. The injection-moldable double-chamber pre-filled and sealed syringe as claimed in claim 1, wherein the powder segment (5) and the liquid segment (4) are connected by screw thread fit; the outer wall of one end of the liquid section (4) is provided with an external thread (41), and the inner wall of one end of the powder section (5) is provided with an internal thread (51) matched with the external thread (41); a sealing structure is arranged between the powder section (5) and the liquid section (4).
3. An injection moldable dual chamber pre-filled and sealed syringe as claimed in claim 2, characterized in that the sealing structure comprises a wedge structure concave surface (42) and a wedge structure convex surface (52) which are connected with each other, the wedge structure concave surface (42) is arranged between the external thread (41) and the inner wall of the liquid segment (4); the one end that lies in internal thread (51) on powder section (5) is connected with joint design (53), is equipped with wedge structure convex surface (52) between the outer wall of joint design (53) and powder section (5) inner wall, is equipped with the recess that matches with wedge structure concave surface (42) between the outer wall of internal thread (51) and joint design (53), and closely the cover of wedge structure concave surface (42) is pasted on wedge structure convex surface (52).
4. An injection moldable dual chamber pre-filled and sealed syringe as claimed in claim 1, wherein the sealed chamber of said liquid segment (4) is filled with a liquid (8); the powder section (5) is filled with freeze-dried powder (7).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111149536.6A CN113855933A (en) | 2021-09-29 | 2021-09-29 | But injection moulding two-chamber embedment syringe in advance |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202111149536.6A CN113855933A (en) | 2021-09-29 | 2021-09-29 | But injection moulding two-chamber embedment syringe in advance |
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CN113855933A true CN113855933A (en) | 2021-12-31 |
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CN202111149536.6A Pending CN113855933A (en) | 2021-09-29 | 2021-09-29 | But injection moulding two-chamber embedment syringe in advance |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0144551A1 (en) * | 1983-09-28 | 1985-06-19 | Becton Dickinson and Company | Two-component medication syringe assembly |
US4613326A (en) * | 1985-07-12 | 1986-09-23 | Becton, Dickinson And Company | Two-component medication syringe assembly |
CN201921234U (en) * | 2010-12-10 | 2011-08-10 | 山东省药用玻璃股份有限公司 | Double-cavity pre-encapsulated syringe |
KR20130081481A (en) * | 2012-01-09 | 2013-07-17 | 백우인 | Syringe |
CN103285454A (en) * | 2012-02-29 | 2013-09-11 | 山东威高集团医用高分子制品股份有限公司 | Double-chamber multifunctional pre-encapsulation injector |
CN108065999A (en) * | 2016-11-11 | 2018-05-25 | 贺利氏医疗有限公司 | For storing and mixing the device and method of bone cement |
CN110496274A (en) * | 2019-09-24 | 2019-11-26 | 山东威高普瑞医药包装有限公司 | A kind of molten medicinal pre-encapsulated injector and a kind of dispenser |
-
2021
- 2021-09-29 CN CN202111149536.6A patent/CN113855933A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0144551A1 (en) * | 1983-09-28 | 1985-06-19 | Becton Dickinson and Company | Two-component medication syringe assembly |
US4613326A (en) * | 1985-07-12 | 1986-09-23 | Becton, Dickinson And Company | Two-component medication syringe assembly |
CN201921234U (en) * | 2010-12-10 | 2011-08-10 | 山东省药用玻璃股份有限公司 | Double-cavity pre-encapsulated syringe |
KR20130081481A (en) * | 2012-01-09 | 2013-07-17 | 백우인 | Syringe |
CN103285454A (en) * | 2012-02-29 | 2013-09-11 | 山东威高集团医用高分子制品股份有限公司 | Double-chamber multifunctional pre-encapsulation injector |
CN108065999A (en) * | 2016-11-11 | 2018-05-25 | 贺利氏医疗有限公司 | For storing and mixing the device and method of bone cement |
CN110496274A (en) * | 2019-09-24 | 2019-11-26 | 山东威高普瑞医药包装有限公司 | A kind of molten medicinal pre-encapsulated injector and a kind of dispenser |
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Application publication date: 20211231 |