CN112881735A - Sample frame management and conveying device and biochemical immunization assembly line - Google Patents
Sample frame management and conveying device and biochemical immunization assembly line Download PDFInfo
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- CN112881735A CN112881735A CN202110363631.XA CN202110363631A CN112881735A CN 112881735 A CN112881735 A CN 112881735A CN 202110363631 A CN202110363631 A CN 202110363631A CN 112881735 A CN112881735 A CN 112881735A
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- 238000002649 immunization Methods 0.000 title claims abstract description 6
- 230000003053 immunization Effects 0.000 title claims abstract description 6
- 230000007246 mechanism Effects 0.000 claims abstract description 119
- 238000001514 detection method Methods 0.000 claims abstract description 73
- 230000005540 biological transmission Effects 0.000 claims abstract description 32
- 230000000903 blocking effect Effects 0.000 claims description 16
- 238000005070 sampling Methods 0.000 claims description 14
- 238000009434 installation Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 230000000712 assembly Effects 0.000 claims description 3
- 238000000429 assembly Methods 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims description 2
- 238000010168 coupling process Methods 0.000 claims description 2
- 238000005859 coupling reaction Methods 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 238000011084 recovery Methods 0.000 abstract description 5
- 230000001360 synchronised effect Effects 0.000 description 12
- 230000007723 transport mechanism Effects 0.000 description 8
- 238000012360 testing method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 239000002699 waste material Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/0092—Scheduling
- G01N35/0095—Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
- G01N2035/00831—Identification of carriers, materials or components in automatic analysers nature of coded information identification of the sample, e.g. patient identity, place of sampling
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a sample rack management and conveying device and a biochemical immunization assembly line, wherein the sample rack management and conveying device comprises a mounting structure, a sample rack management structure, a sample rack carrying mechanism, an information reading structure and a sample rack force transmission system, and the sample rack force transmission system comprises a bearing piece; the sample frame rail-changing mechanism is provided with a rail-changing rail and a guide rail; and a sample rack transfer mechanism having a first and a second transfer mechanism. The sample rack carrying mechanism carries the sample rack into the rail transfer track, and the rail transfer track pushes the sample rack to the first conveying mechanism and conveys the sample rack downwards in a relay way through the first conveying mechanism; the second conveying mechanism conveys the returned sample rack to the orbital transfer track or the guide track, so that relay conveying and recovery of the sample rack among different detecting instruments are realized, online detection efficiency is improved, online detection requirements of clinical high-throughput samples are effectively met, and waiting time of patients is shortened.
Description
Technical Field
The invention relates to a biochemical immunization assembly line, in particular to a sample rack management and conveying device and a biochemical immunization assembly line comprising the sample rack management and conveying device.
Background
The sample transmission mode in the full-automatic in-vitro diagnosis analyzer (such as nucleic acid analyzer, full-automatic luminescence chemical immunity analyzer, etc.) in the market mainly includes two sample tray sample introduction modes and sample rack track sample introduction modes.
The sample tray advances a kind mode and places the sample in the sample tray, comes the transport of sample through rotating the sample tray when detecting, however because the sample tray is circular structure, it can't load and unload the sample in the testing process, can't realize the transport of sample between different detecting instrument, and then can't satisfy biochemical immune assembly line's continuous detection demand. Therefore, the existing high-end fully automatic detection instruments (such as biochemical immune flow lines) mostly adopt a sample rack rail sample injection mode to ensure the continuous detection of high-throughput samples.
The conventional sample rack transmission system comprises three major parts, namely a sample rack management structure, a sample carrying mechanism and a bar code reading structure, wherein the sample management structure is provided with an emergency treatment groove and a storage groove (used for storing a sample rack), and the emergency treatment groove can be used for emergency samples so as to meet the emergency treatment requirement of the emergency samples in clinic; the sample handling mechanism is provided with a handling groove for containing a sample rack and a pushing handle driven by a three-axis transmission mechanism, the pushing handle pushes the sample rack capable of being stored in the handling groove into the handling groove and pushes the sample rack in the handling groove into a scanning position on one side of the bar code reading structure, so that a detection instrument can conveniently sample after reading information, and then detection and analysis of a certain detection item are realized. However, the sample rack transport system cannot meet the online detection requirements of more than two high-throughput detection instruments (including biochemical instruments and immunity instruments).
In order to solve the problems, some enterprises adjust the installation positions of the online equipment and the sample rack transmission system, two or more detection instruments are arranged on one side of the sample rack management structure side by side, the sample rack is pushed to the scanning position corresponding to the first detection instrument during detection, the sample rack is pushed to the scanning position of the second detection instrument after sampling, and the like is carried out until all online equipment finishes sampling work and then pushes the sample rack to the initial storage position or the waste position. However, although the sample rack transmission system realizes the pipeline detection of a plurality of detection instruments, the online instruments are required to sample one by one, so that the waiting sampling time of each detection instrument is long, the detection efficiency is low, and the detection requirement of clinical high-throughput samples cannot be met; in addition, when the number of on-line detection devices is large, the sample rack transmission system needs a long movement space to meet the on-line detection requirement, occupies a large space, and is expensive.
Disclosure of Invention
In view of the above, the present invention provides a sample rack management and transportation device, and further provides a biochemical immunoassay assembly line including the sample rack management and transportation device, so as to implement flexible relay transmission and recovery of sample racks, implement online detection of samples, and improve online detection efficiency of the biochemical immunoassay assembly line.
In order to achieve the purpose, the invention adopts the following technical scheme:
the sample rack management and conveying device comprises a mounting structure, a sample rack management structure with an emergency treatment groove and a storage groove, a sample rack conveying mechanism with a pushing handle and a conveying groove, and an information reading structure; also comprises a sample frame relay transmission system, the sample frame relay transmission system comprises
The supporting piece is horizontally arranged on the right side of the information reading structure, and the left end part of the supporting piece is used for reading code bits;
the sample frame track changing mechanism is arranged on the rear side of the supporting piece and is provided with a track changing track and a guide track which horizontally move on the upper surface of the supporting piece, the track changing track and the guide track are arranged along the front and rear directions, the track changing track is positioned at the code reading position, and the guide track is positioned at the second conveying mechanism; and
the sample rack conveying mechanism is arranged on the right side of the supporting piece and is provided with a first conveying mechanism and a second conveying mechanism which are used for conveying the sample rack to the next detection instrument, and the first conveying mechanism and the second conveying mechanism are arranged at left and right intervals;
the sample rack conveying mechanism conveys the sample rack stored in the storage groove to a first detection instrument, the sample rack conveying mechanism conveys the sample rack after primary sampling into the orbital transfer track, and the orbital transfer track pushes the sample rack to the first conveying mechanism and conveys the sample rack to the next detection instrument through the first conveying mechanism; the second transfer mechanism transfers the returned sample rack to the track transfer rail or the guide rail.
In a preferred embodiment of the present invention, the scanning is located at the left end portion in the supporting bracket, the inlet end of the scanning position has an inlet guide rail, and the supporting member corresponding to the scanning position is provided with a through slot matched with the pushing handle of the sample rack carrying mechanism, and the pushing handle pushes the sample rack into and out of the scanning position along the through slot.
In a preferred embodiment of the present invention, a sample rack positioning structure is disposed at an inlet end of the scanning position, and the sample rack positioning structure has a torsion spring and a positioning roller vertically penetrating through one end of the torsion spring; one side plate of the inlet guide track is provided with a notch, and the positioning roller is positioned in the notch and positions the sample rack entering the scanning position.
In a preferred embodiment of the present invention, the sample rack rail-changing mechanism includes a first base disposed along the left-right direction, a first connecting assembly driven by a linear power source is disposed on the first base, the rail-changing rail is disposed on the upper portion of the first connecting assembly and arranged along the front-rear direction, an initial station of the rail-changing rail is located at the scanning position, and an initial station of the guide rail is located at the second conveying mechanism;
still be provided with reset spring on the first base, reset spring's one end with the second coupling assembling of guide rail tip is connected, and reset spring's the other end sets up on being close to orbital first base of becoming the rail.
In a preferred embodiment of the present invention, the sample rack transport mechanism further includes a rack disposed on a right side of the sample rack management structure, and the first transport mechanism and the second transport mechanism are disposed on the rack at a left-right interval.
In a preferred embodiment of the present invention, the first conveyor mechanism includes a first conveyor belt driven by a first power source, the second conveyor mechanism includes a second conveyor belt driven by a second power source, the first conveyor belt and the second conveyor belt are spaced apart from each other in the left-right direction, and the upper conveying sections of the first conveyor belt and the second conveyor belt are arranged in the front-rear direction.
In a preferred embodiment of the present invention, the front portion of the upper conveying section of the first conveyor belt and the front portion of the upper conveying section of the second conveyor belt both extend forward to form the support, a first conveying track for limiting the sample rack is arranged on the rack corresponding to the front portion of the upper conveying section of the first conveyor belt, and a second conveying track for limiting the sample rack is arranged on the rack corresponding to the front portion of the upper conveying section of the second conveyor belt.
In a preferred embodiment of the present invention, a first blocking structure for preventing the sample rack from being accumulated is provided at an entrance end of the first conveying track, and a second blocking structure for preventing the sample rack from being accumulated is provided at an exit end of the second conveying track.
In a preferred embodiment of the present invention, the sample rack transport mechanism further includes a pair of tension members disposed on the floor of the rack, the mounting member of the tension member has a horizontally disposed tension spring, and the elastic portion of the tension spring abuts against the first power source or the second power source.
The biochemical immune assembly line comprises at least two online detection instruments, wherein a sample rack pipeline and a conveying device which are novel in practical use are arranged on one side of one detection instrument and between every two adjacent detection instruments, so that online transmission of a sample rack can be realized, online detection of samples is further realized, and online detection efficiency is improved; meanwhile, the number of the storage tanks can be doubled, the detection requirement of a high-flux detection instrument is met, and a foundation is laid for improving the online detection efficiency of the biochemical immune assembly line.
The invention realizes the relay transmission of the sample rack between different detecting instruments and the recovery of the sample after online sampling (convenient for retesting) by arranging the sample rack management and conveying device at one side of one detecting instrument and between every two adjacent online detecting instruments, improves the online detecting efficiency by more than three times, effectively meets the online detecting requirement of high-flux samples in clinic and shortens the waiting time of patients. Specifically, the method comprises the following steps:
the sample rack carrying mechanism can directly push the sample rack to the sample conveying mechanism of the first detection instrument, so that the sample can be scanned and sampled; during online detection, the sample rack carrying mechanism can push the sampled sample rack to the sample rack connecting force transmission system, the sample rack sampled by the first detection instrument is pushed to the relay conveying mechanism of the first detection instrument through the sample rack connecting force transmission system, and the sample rack is pushed to the sample rack management and conveying device between the first detection instrument and the second detection instrument through the relay conveying mechanism, so that relay transmission and sampling detection of the sample rack are realized, and the detection efficiency of the sample is improved. Meanwhile, during actual installation, a sample rack management and conveying device can be installed between any two adjacent detection instruments, relay transmission of the sample rack between any two adjacent detection instruments is achieved, the number of storage grooves can be multiplied, the sample rack management and conveying device is suitable for high-flux detection instruments, sample transmission and detection efficiency is improved, and waiting time of detection reports is shortened.
Drawings
Fig. 1 is a schematic structural view of a sample rack management and transport apparatus according to the present invention.
Fig. 2 is an enlarged schematic view of a portion a in fig. 1.
Fig. 3 is an isometric view of the specimen rack transport mechanism of fig. 1 (omitting the first timing belt drive mechanism).
Fig. 4 is an installation view of the driving motor and the push handle in fig. 3.
Fig. 5 is an isometric view of the information reading structure of fig. 1.
Fig. 6 is a schematic diagram of the sample rack force transfer system of fig. 1.
Fig. 7 is a schematic structural diagram of the sample rack orbital transfer track in fig. 6.
Fig. 8 is a schematic structural view of the specimen rack transport mechanism in fig. 6.
Fig. 9 is an enlarged schematic view of the portion C in fig. 8.
Fig. 10 is an enlarged schematic view of a portion B in fig. 8.
Detailed Description
It should be noted that all the directional indicators (such as up, down, left, right, front, and back … …) in the embodiment of the present invention are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture, if the specific posture is changed, the directional indicator is changed accordingly.
It should also be noted that the description herein as relating to "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying any relative importance or implicit indication of the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature.
The following describes embodiments of the present invention in detail with reference to the drawings, which are implemented on the premise of the technical solution of the present invention, and detailed embodiments and specific operation procedures are provided, but the scope of the present invention is not limited to the following embodiments.
As shown in fig. 1-2, the specimen rack management and transport apparatus of the present invention includes a mounting structure having a second base 100 disposed in a left-right direction;
as shown in fig. 1, the sample rack management structure is erected above the second base 100, and has a plurality of storage slots 200 arranged from left to right (each storage slot 200 has a through slot on the bottom wall thereof, so that a pushing handle 307 described later can pass through and push the sample rack in the storage slot 200 into a carrying slot 311 described later or push the sample rack in the carrying slot 311 into the storage slot 200 described later), and the storage slot on the left side is an emergency position F, so that the rapid detection of an emergency sample can be realized, and the detection requirement of a clinical emergency sample can be met;
as shown in fig. 1 and fig. 3 to 4, the sample rack carrying mechanism has a mounting base 301 slidably disposed on a first guide rail 303 of the second base 100 and a first synchronous belt transmission mechanism 302 disposed on the second base 100, and the first synchronous belt transmission mechanism 302 drives the mounting base 301 to horizontally move left and right along the first guide rail 303; the mounting base 301 is also provided with a sliding base 304 which is arranged in the mounting base 301 in a sliding manner, a second synchronous belt transmission mechanism 305 is also arranged in the mounting base 301, and the second synchronous belt transmission mechanism 305 drives the sliding base 304 to horizontally move back and forth along a second guide rail 306 on the mounting base 301; the device is also provided with a push handle 307 arranged on the sliding seat 304, the sliding seat 304 is provided with a power source for driving the push handle 307 to lift, the power source comprises a first motor 308 and a cam 309 driven by the first motor 308, one end of the push handle 307 is provided with a roller 310 tangent to the cam 309, and the first motor 308 drives the push handle 307 to ascend and descend through the cam 309 and the roller 310 so as to realize the height adjustment of the push handle 307 and meet different operation requirements; the sample rack carrying mechanism further comprises a carrying groove 311 arranged at the upper part of the mounting seat 301 (a guide groove for the push handle 307 to pass through is formed in the bottom wall of the carrying groove 311);
as shown in fig. 5, the information reading structure 40 has a base plate 401 vertically disposed at the right side of the sample rack management structure, a bar code scanner 402 disposed on the base plate 401 (for scanning information for reading the sample rack and the sample), and a high cup sensor 403 (for detecting the height of the cuvettes), a low cup sensor 404 (for detecting the height of the cuvettes) disposed on the base plate 401; and
a sample rack force transfer system, wherein: as shown in FIGS. 1 and 7, the sample rack force transfer system includes
The supporting piece is a supporting plate 501.1 horizontally arranged on the right side of the information reading structure 40, the left end part of the supporting plate 501.1 close to the information reading structure 40 is a scanning position, and the information of the sample is read when the sample rack moves to the scanning position;
the sample frame rail transfer mechanism is provided with a rail transfer track 502.1 and a guide track 502.2 which are driven by a linear power source, the rail transfer track 502.1 and the guide track 502.2 are arranged along the front and back directions, and the rail transfer track 502.1 can move left and right on a bearing plate 501.1 to realize the transfer of the sample frame;
the sample rack conveying mechanism is arranged on the right side of the bearing plate 501.1 and is provided with a first conveying mechanism and a second conveying mechanism, a first conveying belt 503.1 of the first conveying mechanism and a second conveying belt 503.2 of the second conveying mechanism are arranged at intervals left and right, and the heights of the upper surfaces of the first conveying belt 503.1 and the second conveying belt 503.2 are consistent with the height of the upper surface of the bearing plate 501.1, so that a sample rack can be moved among the bearing plate 501.1, the first conveying belt 503.1 and the second conveying belt 503.2;
the initial position of the orbital transfer track 502.1 is located at a scanning position, and a sample rack at the scanning position can be limited; the initial position of the guide track 502.2 is located at the rear part of the second conveyor belt 503.2, when detecting, the sample racks are stored in the storage tank 200 in sequence, the carrying tank 311 corresponds to the storage tank 200 in front and back, the push handle 307 penetrates out of the through groove of the storage tank 200 upwards to push the sample racks in the storage tank 200 into the carrying tank 311, the sample rack carrying mechanism moves horizontally rightwards to enable the carrying tank 311 to correspond to the scanning position of the bearing plate 501.1 in front and back, the push handle 307 pushes the sample racks in the carrying tank 311 into the track transfer track 502.1, the barcode scanner 402 scans sample information, and a detection instrument records the information of each sample;
after information is read, the orbital transfer track 502.1 horizontally pushes the sample frame to the right onto the first conveyor belt 503.1, and the first conveyor belt 503.1 conveys the sample frame to a conveyor belt matched with a next detection instrument, so that relay conveying of the sample is realized, and a foundation is laid for online detection of the detection instrument; the sample rack after on-line detection can return to the second conveying mechanism and is pushed by the orbital transfer track 502.1 to move leftwards to the scanning position, the sample rack carrying mechanism pushes the waste sample rack into the initial storage tank 200, the on-line detection of the sample in the production line is realized, and simultaneously, the sample rack after on-line detection is sequentially returned into the storage tank 200, so that the retest is facilitated.
As shown in fig. 2 and fig. 6, an inlet guide track 501.2 is provided at the front of the supporting plate 501.1 corresponding to the scanning position, so that the sample rack on the sample rack carrying mechanism can enter the scanning position from the inlet guide track 501.2 under the action of the pushing handle 307, and the information reading structure 40 reads the sample;
as shown in fig. 1 and 6, a through groove 501.3 is formed in the supporting plate 501.1 corresponding to the scanning position in the front-back direction, when the sample after on-line detection is returned to the scanning position, the push handle 307 of the sample rack conveying mechanism pushes the detected sample rack into the conveying groove 311 of the sample rack conveying mechanism from the rear end of the through groove 501.3, and then the sample rack is conveyed to the initial storage position by the sample rack conveying mechanism, so that the recovery management of the sample rack is realized.
As shown in fig. 2, the left side plate of the inlet guide track 501.2 has a notch 504.3; one side of import guide rail 501.2 still is provided with the sample frame location structure that advances line location to the sample frame that gets into the scanning position, and sample frame location structure includes the installation axle 504.1 of a vertical setting, and the cover is equipped with a torsion spring 504.2 on the installation axle 504.1, and the one end level of torsion spring 504.2 extends to vertical upwards bending type behind breach 504.3 department and forms vertical installation section, wears to be equipped with a location gyro wheel 504.4 on the vertical installation section, and location gyro wheel 504.4 is located breach 504.3 department. When the sample rack passes through the positioning roller 504.4, the elasticity of the torsion spring 504.2 is applied to the sample rack through the positioning roller 504.4, and the sample rack is subjected to deviation rectification and positioning.
As shown in fig. 6-7, the sample rack rail-changing mechanism includes a first base 502.3 disposed along the left-right direction, the linear power source (being a third synchronous belt transmission mechanism 502.4) is mounted on a vertical plate of the first base 502.3, and a third guide rail 502.5 extending along the left-right direction is further disposed on the vertical plate; the sample rack rail-changing mechanism further comprises a first connecting assembly 502.6 and a second connecting assembly 502.7 which are arranged on the third guide rail 502.5 in a sliding mode, the lower portion of the first connecting assembly 502.6 is fixedly connected to the ascending section of the synchronous belt of the linear power source, the middle portion of the first connecting assembly 502.6 is provided with a sliding block clamped on the third guide rail 502.5, and the rail-changing track 502.1 is horizontally arranged on the upper portion of the first connecting assembly 502.6; the second connecting assembly 502.7 moves along the third guide rail 502.5 through the slider, and the upper part of the second connecting assembly 502.7 is horizontally provided with a guide rail 502.2 horizontally extending in the front-rear direction, and the guide rail 502.2 and the track changing rail 502.1 are arranged at intervals left and right;
a horizontally arranged return spring 502.8 (preferably a tension spring) is further arranged on the vertical plate, one end of the return spring 502.8 is positioned on the vertical plate corresponding to the initial position of the track transfer rail 502.1, and the other end of the return spring 502.8 is connected with the second connecting component 502.7; the initial position of the guide track 502.2 is located at the second conveyor belt 503.2, the initial position of the orbital transfer track 502.1 is located at the scanning position, and the sample rack at the scanning position is guided and limited; when the on-line detection is performed, the orbital transfer track 502.1 pushes the sample rack at the scanning position to the first conveyor belt 503.1, the sample rack is conveyed to the relay conveying mechanism of the next detecting instrument by the first conveyor belt 503.1, the sample rack returned by the detecting instrument is conveyed to the second conveyor belt 503.2, and the sample rack is guided to the relay conveying mechanism of another detecting instrument by the guide track 502.2 (of course, the sample rack can also be recovered to the storage tank 200 by the orbital transfer track 502.1 and the sample rack conveying mechanism); the sample rack sampled by another detecting instrument can be conveyed to the second conveyor belt 503.2 by the return conveying mechanism, at this time, the track changing track 502.1 moves to the second conveyor belt 503.2 and pushes the guide track 502.2 open, the track changing track 502.1 pushes the waste sample rack to the scanning position, and the guide track 502.2 automatically resets under the action of the return spring 502.8.
As shown in fig. 6 and 8, the sample rack conveying mechanism further includes a rack 503.3 disposed on the right side of the sample rack management structure, the first conveying mechanism and the second conveying mechanism are disposed on the rack 503.3 at a left-right interval, and the first conveyor belt 503.1 of the first conveying mechanism and the second conveyor belt 503.2 of the second conveying mechanism are disposed at a left-right interval;
the first conveying mechanism comprises a second motor 503.4 which is arranged on the bottom plate of the frame 503.3; a plurality of first belt pulleys arranged on the frame 503.3, wherein one first belt pulley is arranged on a motor shaft of the second motor 503.4; the first conveyor belt 503.1 (an annular conveyor belt) is wound on a first belt wheel, and an upper conveying section of the first conveyor belt 503.1 is horizontally arranged along the front-back direction so as to meet the horizontal conveying requirement of the sample rack; a pair of supporting grooves are formed in a top plate of the rack 503.3 at intervals, an upper conveying section of the first conveying belt 503.1 is located in one supporting groove, and the height of the top surface of the groove wall of the supporting groove is consistent with the height of the upper surface of the supporting plate 501.1 and the height of the upper surface of the first conveying belt 503.1, so that the track transfer track 502.1 can push a sample rack at a scanning position to the first conveying belt 503.1; the middle front part of the upper conveying section of the first conveyor belt 503.1 is located at the front side of the supporting plate 501.1, and the two sides of the middle front part of the upper conveying section of the first conveyor belt 503.1 are provided with first conveying rails 503.5 for guiding and limiting the sample rack, so that the sample rack is ensured to enter a conveying mechanism matched with a detection instrument, and the relay conveying of the sample rack is realized.
The second transport mechanism comprises a third motor 503.6, arranged on the bottom plate of the frame 503.3; a plurality of second belt pulleys arranged on the second frame 503.3, wherein one second belt pulley is arranged on a motor shaft of the third motor 503.6; a second conveyor belt 503.2 (an endless conveyor belt) wound around a plurality of second pulleys, wherein an upper conveying section of the second conveyor belt 503.2 is horizontally arranged along the front-rear direction; the upper conveying section of the second conveyor belt 503.2 is located in another supporting groove of the rack 503.3, and the bottom surface of the supporting groove supports the second conveyor belt 503.2, so that the conveying stability of the sample rack is improved; the height of the upper surface of the second conveyor belt 503.2 is consistent with that of the upper surface of the support plate 501.1, so that the orbital transfer rail 502.1 and the guide rail 502.2 can move to the second conveyor belt 503.2, and the sample rack is transferred; the middle front part of the upper conveying section of the second conveyor belt 503.2 is located at the front side of the support plate 501.1, and the middle front part of the upper conveying section of the second conveyor belt 503.2 is provided with a second conveying rail 503.7 for guiding and limiting the sampled sample rack.
As shown in fig. 8 to 9, the sample rack transport mechanism further includes a pair of tensioning assemblies disposed on the floor of the rack 503.3, the two tensioning assemblies have the same structure and each include a base 505.1 disposed on the bottom plate of the rack 503.3, and a tensioning spring 505.2 is horizontally disposed on the base 505.1; the elastic part of the tension spring 505.2 of one tension assembly abuts against the second motor 503.4 (preferably a stepping motor), and the elastic part of the other tension spring 505.2 abuts against the third motor 503.6; the motor base of the third motor 503.6 and the motor base of the second motor 503.4 are both sliding bases with guide grooves, two linear guide rails 505.3 are arranged on the bottom plate of the frame 503.3 at intervals, the motor base of the third motor 503.6 is clamped on one of the linear guide rails 505.3, and the motor base of the second motor 503.4 is clamped on the other linear guide rail 505.3. In the operation process of the first conveying mechanism and the second conveying mechanism, the elastic part of the tension spring 505.2 is always abutted against the second motor 503.4 or the third motor 503.6, so that the second motor 503.4 or the third motor 503.6 slides linearly along the linear guide 505.3 under the action of the tension spring 505.2, the first conveyor belt 503.1 and the second conveyor belt 503.2 are always in a tension state, and the conveying stability of the sample rack is improved.
As shown in fig. 6 and 8, the entrance end of the first conveyor track 503.5 is provided with a first blocking structure 506 for preventing the sample rack from accumulating, and the exit end of the second conveyor track 503.2 is provided with a second blocking structure 507 for preventing the sample rack from accumulating, and the first blocking structure 506 and the second blocking structure 507 have the same structure. Taking the first blocking structure 506 as an example: as shown in fig. 10, the first blocking structure 506 includes a mounting bracket 506.1 disposed on the frame 503.3; a driving motor 506.2 arranged on the mounting frame 506.1; a baffle 506.3 arranged on the motor shaft of the driving motor 506.2, wherein the baffle 506.3 is provided with a release position (the baffle 506.3 is in a vertical state and releases the sample rack) and a blocking position (the baffle 506.3 is in a horizontal state and is positioned above the first conveying track 503.5 and blocks the sample rack from entering the first conveying track 503.5); the first blocking structure 506 further comprises an origin sensor 506.4 arranged at the upper part of the mounting frame 506.1, the mounting part of the baffle 506.3 is provided with a trigger piece 506.5 for triggering the origin sensor 506.4, the state of the baffle 506.3 is mastered, the sample rack is flexibly switched between the release position and the blocking position, and the sample rack is prevented from being accumulated;
the second blocking structure 507 is arranged at the output end of the second conveyor belt 503.2, and not only can block a sample rack entering the next detecting instrument for a preset time to convey the sample rack according to a preset interval, but also can block the sample rack during recovery and relay conveyance, and the sample rack does not move forward under the resistance of the second blocking structure 507 after moving to a preset position, so that the rail transfer track 502.1 can push the recovered sample rack to a scanning position.
In another embodiment of the invention: the invention also provides a biochemical immune assembly line, which comprises three detecting instruments (certainly, two detecting instruments or four or more detecting instruments can be used), wherein one side of the first detecting instrument is provided with a sample rack managing and conveying device, and a sample rack managing and conveying device is respectively arranged between every two adjacent detecting instruments so as to realize online detection. The specific on-line detection process is as follows:
placing the sample frames containing the samples in the storage tank 200 one by one, moving a push handle 307 of the sample frame carrying mechanism to the storage tank 200, moving the push handle 307 to the rear side of the storage tank 200 by a second synchronous belt transmission mechanism 305, enabling the push handle 307 to extend upwards out of a through groove at the bottom of the storage tank 200 by the operation of a first motor 308, driving the push handle 307 to move by the second synchronous belt transmission mechanism 305, pushing the sample frames into a carrying groove 311 by the push handle 307 in the moving process, and carrying the sample frames to a preset position by the sample frame carrying mechanism;
after the sample rack carrying mechanism reaches a preset position, the second synchronous belt transmission mechanism 305 moves the push handle 307 to the rear side of the carrying groove 311, the first motor 308 works to enable the push handle 307 to extend upwards out of the through groove on the bottom wall of the carrying groove 311, the second synchronous belt transmission mechanism 305 drives the push handle 307 to move forwards, the sample rack is pushed to a sample conveying mechanism of the first detection instrument, and then sampling operation is carried out; after sampling, the sample conveying mechanism of the first detection instrument pushes the sample rack into the carrying groove 311;
after the first detecting instrument samples, if the sample does not need to be processed online, the sample rack carrying mechanism conveys the sample rack in the carrying groove 311 into the storage groove 200, and the sample is recovered so as to be convenient for retesting;
after the first detecting instrument samples, if the sample needs to be operated online, the sample rack carrying mechanism moves to the front and back alignment of the carrying groove 311 and the inlet guide track 501.2, the push handle 307 moves to the front side of the carrying groove 311 and enables the sample rack in the carrying groove 311 to enter the orbital transfer track 502.1 at the scanning position through the inlet guide track 501.2, the bar code scanner 402 reads the information of the sample and detects the height of a reaction cup containing the sample, and the sampling height of a sampling needle of each detecting instrument is further ensured;
after the sample information is successfully read, the third synchronous belt transmission mechanism 502.4 drives the orbital transfer track 502.1 and the sample rack to move to the first conveying belt 503.1 of the first conveying mechanism, the orbital transfer track 502.1 and the first conveying track 503.5 are aligned front and back, and the sample rack is guided, so that the sample rack is conveyed to a relay conveying mechanism (provided with two conveying belts arranged at intervals to meet the relay conveying and relay returning requirements of the sample rack) of the first detecting instrument under the action of the first conveying belt 503.1; in the process of detecting the sample rack assembly line, the first blocking structure 506 at the inlet of the first conveying track 503.5 blocks the sample rack to stop the sample rack for a preset time, so as to prevent the sample rack from accumulating on the relay conveying mechanism of the first detecting instrument;
after the sample rack is moved in place, the relay conveying mechanism pushes the sample rack into a track transfer track of a second sample rack management and conveying device (at the moment, the track transfer track of the sample rack management and conveying device is aligned with a second first conveying track 503.5 front and back), then a second third synchronous belt transmission mechanism 502.4 drives the track transfer track 502.1 and the sample rack to make the second track transfer track aligned with a second inlet guide track 501.2 front and back (at the moment, a conveying groove 311 of a second sample rack conveying mechanism is aligned with an inlet guide track 501.2 front and back), after information is read by a second information reading mechanism 40, a pushing handle 307 of the second sample rack conveying mechanism pushes the sample rack into the conveying groove 311, and the sample rack is pushed to a sample conveying mechanism of a second detection instrument through the conveying groove, and then sampling operation is carried out; after sampling is finished, the sample conveying mechanism of the second detection instrument pushes the sample rack into the conveying groove of the second sample rack conveying mechanism, and online operation of the two detection instruments is finished;
after the second detecting instrument finishes sampling, if online detection is still needed, repeating the relay transmission process of the second detecting instrument and the first detecting instrument, and transmitting the sample frame to a sample conveying mechanism of a third detecting instrument; after the second testing apparatus samples, if the sample does not need to be tested on-line, the second testing apparatus pushes the sample rack to the second track-changing track 502.1, the track-changing track 502.1 changes the sample rack to the second conveyor 503.2, the sample rack is conveyed to the relay conveying mechanism of the first testing apparatus connected to the second testing apparatus, when the relay conveying mechanism of the first testing apparatus pushes the sample rack to the first second conveying track 503.7 connected to the first testing apparatus, the first track-changing track 502.1 is aligned with the second conveying track 503.7, the sampled sample rack is pushed to the scanning position of the first sample rack management and conveying apparatus, and is pushed into the corresponding conveying groove 311 by the first pushing hand 307, and is pushed into the initial storage groove 200 of the sample rack by the sample rack conveying mechanism.
It should be emphasized that the above-described embodiments are merely exemplary embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive various equivalent modifications, substitutions, improvements, etc. within the technical scope of the present invention, and these modifications and improvements should be covered by the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. A sample rack management and conveying device comprises a mounting structure, a sample rack management structure with an emergency treatment groove and a storage groove, a sample rack conveying mechanism with a pushing handle and a conveying groove, and an information reading structure; the method is characterized in that: also comprises a sample frame relay transmission system, the sample frame relay transmission system comprises
The supporting piece is horizontally arranged on the right side of the information reading structure, and the left end part of the supporting piece is used for reading code bits;
the sample frame track changing mechanism is arranged on the rear side of the supporting piece and is provided with a track changing track and a guide track which horizontally move on the upper surface of the supporting piece, the track changing track and the guide track are arranged along the front and rear directions, the track changing track is positioned at the code reading position, and the guide track is positioned at the second conveying mechanism; and
the sample rack conveying mechanism is arranged on the right side of the supporting piece and is provided with a first conveying mechanism and a second conveying mechanism which are used for conveying the sample rack to the next detection instrument, and the first conveying mechanism and the second conveying mechanism are arranged at left and right intervals;
the sample rack conveying mechanism conveys the sample rack stored in the storage groove to a first detection instrument, the sample rack conveying mechanism conveys the sample rack after primary sampling into the orbital transfer track, and the orbital transfer track pushes the sample rack to the first conveying mechanism and conveys the sample rack to the next detection instrument through the first conveying mechanism; the second transfer mechanism transfers the returned sample rack to the track transfer rail or the guide rail.
2. The specimen rack management and transport device of claim 1, wherein: the scanning is positioned at the left end part in the bearing bracket, the inlet end of the scanning position is provided with an inlet guide rail, the bearing piece at the position corresponding to the scanning position is provided with a through groove matched with the pushing handle of the sample frame carrying mechanism, and the pushing handle pushes the sample frame to enter and exit the scanning position along the through groove.
3. The specimen rack management and transport device of claim 2, wherein: a sample frame positioning structure is arranged at the inlet end of the scanning position, and the sample frame positioning structure is provided with a torsion spring and a positioning roller vertically penetrating through one end part of the torsion spring; one side plate of the inlet guide track is provided with a notch, and the positioning roller is positioned in the notch and positions the sample rack entering the scanning position.
4. The specimen rack management and transport device of claim 1, wherein: the sample frame rail transfer mechanism comprises a first base arranged along the left-right direction, a first connecting assembly driven by a linear power source is arranged on the first base, a rail transfer rail is arranged on the upper portion of the first connecting assembly and is arranged along the front-back direction, an initial station of the rail transfer rail is located at the scanning position, and an initial station of the guide rail is located at the second conveying mechanism;
still be provided with reset spring on the first base, reset spring's one end with the second coupling assembling of guide rail tip is connected, and reset spring's the other end sets up on being close to orbital first base of becoming the rail.
5. The specimen rack management and transport device of claim 1, wherein: the sample rack conveying mechanism further comprises a rack arranged on the right side of the sample rack management structure, and the first conveying mechanism and the second conveying mechanism are arranged on the rack at left and right intervals.
6. The specimen rack management and transport device of claim 5, wherein: the first conveying mechanism is provided with a first conveying belt driven by a first power source, the second conveying mechanism is provided with a second conveying belt driven by a second power source, the first conveying belt and the second conveying belt are arranged at left and right intervals, and an upper conveying section of the first conveying belt and an upper conveying section of the second conveying belt are arranged along the front-back direction.
7. The specimen rack management and transport device of claim 6, wherein: the front part of the upper conveying section of the first conveying belt and the front part of the upper conveying section of the second conveying belt extend forwards to form the bearing piece, a first conveying track for limiting the sample rack is arranged on the rack corresponding to the front part of the upper conveying section of the first conveying belt, and a second conveying track for limiting the sample rack is arranged on the rack corresponding to the front part of the upper conveying section of the second conveying belt.
8. The specimen rack management and transport device of claim 7, wherein: the inlet end of the first conveying track is provided with a first blocking structure for preventing the sample racks from accumulating, and the output end of the second conveying track is provided with a second blocking structure for preventing the sample racks from accumulating.
9. The specimen rack management and transport device of claim 7, wherein: the sample rack conveying mechanism further comprises a pair of tensioning assemblies arranged on the rack floor, a horizontally arranged tensioning spring is arranged on an installation part of each tensioning assembly, and an elastic part of each tensioning spring abuts against the first power source or the second power source.
10. A biochemical immunization pipeline, which is characterized in that: the sample rack pipeline and conveying device comprises at least two online detection instruments, wherein the sample rack pipeline and the conveying device are arranged on one side of one detection instrument and between two adjacent detection instruments, and the sample rack pipeline and the conveying device are arranged according to any one of claims 1 to 9.
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| CN113533763A (en) * | 2021-06-30 | 2021-10-22 | 深圳普门科技股份有限公司 | Conveying device, detection equipment and sampling method |
| CN114152766A (en) * | 2022-02-10 | 2022-03-08 | 深圳市帝迈生物技术有限公司 | Sample analyzer and manual sample feeding assembly thereof |
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